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| Ligand ID (Go to PDB) | DrugBank ID (Go to DrugBank) | Drug Name | Indication | View Results |
|---|---|---|---|---|
| 010 | DB06770(Benzyl alcohol) | Ulesfia (benzyl alcohol) lotion is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia Lotion does not have ovicidal activity. | View | |
| 017 | DB01264(Darunavir) | Darunavir, co-administered with ritonavir, and with other antiretroviral agents, is indicated for the treatment of human immunodeficiency virus (HIV) infection in antiretroviral treatment-experienced adult patients, such as those with HIV-1 strains resistant to more than one protease inhibitor. | View | |
| 032 | DB08881(Vemurafenib) | Vemurafenib is approved since 2011 for the treatment of metastatic melanoma with a mutation on BRAF in the valine located in the exon 15 at codon 600, this mutation is denominated as V600E.[A31270] The V600E mutation, a substitution of glutamic acid for valine, accounts for 54% of the cases of cutaneous melanoma.[A31271] | View | |
| 06X | DB00381(Amlodipine) | For the treatment of hypertension and chronic stable angina. | View | |
| 08D | DB01015(Sulfamethoxazole) | For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections. | View | |
| 08H | DB00404(Alprazolam) | For the management of anxiety disorder or the short-term relief of symptoms of anxiety and for the treatment of panic disorder, with or without agoraphobia. | View | |
| 08J | DB00683(Midazolam) | The midazolam injection is indicated for preoperative sedation/anziolysis/amnesia. It is also an agent for sedation/anziolysis/amnesia prior to or during diagnostic, therapeutic, or endoscopic procedures. Midazolam can also be given intravenously for induction of general anaesthesia. | View | |
| 08Y | DB01200(Bromocriptine) | For the treatment of galactorrhea due to hyperprolactinemia, prolactin-dependent menstrual disorders and infertility, prolactin-secreting adenomas, prolactin-dependent male hypogonadism, as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases, as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. | View | |
| 097 | DB00786(Marimastat) | For the treatment of various cancers | View | |
| 0HK | DB01409(Tiotropium) | Used in the management of chronic obstructive pulmonary disease (COPD). | View | |
| 0LA | DB00821(Carprofen) | For use as a pain reliever in the treatment of joint pain and post-surgical pain. | View | |
| 0LI | DB08901(Ponatinib) | Ponatinib is indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy or Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) that is resistant or intolerant to prior tyrosine kinase inhibitor therapy. | View | |
| 0RN | DB09324(Sulbactam) | Sulbactam is currently available in combination products with ampicillin. Within this formulation it is indicated for the treatment of infections due to susceptible strains of the designated microorganisms in the conditions listed below. | View | |
| 0TX | DB00608(Chloroquine) | For the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis | View | |
| 0U9 | DB01128(Bicalutamide) | For treatment (together with surgery or LHRH analogue) of advanced prostatic cancer. | View | |
| 0WM | DB08916(Afatinib) | Afatinib is a kinase inhibitor indicated as monotherapy [L2937] for the first-line [FDA Label] treatment of (a) Epidermal Growth Factor Receptor (EGFR) TKI (tyrosine kinase inhibitor)-naive adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumours have non-resistant EGFR mutations as detected by an FDA-approved test [FDA Label], and (b) adult patients with locally advanced or metastatic NSCLC of squamous histology progressing on or after platinum-based chemotherapy [FDA Label, L2937]. | View | |
| 115 | DB01095(Fluvastatin) | To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia. | View | |
| 117 | DB01076(Atorvastatin) | May be used as primary prevention in individuals with multiple risk factors for coronary heart disease (CHD) and as secondary prevention in individuals with CHD to reduce the risk of myocardial infarction (MI), stroke, angina, and revascularization procedures. May be used to reduce the risk of cardiovascular events in patients with acute coronary syndrome (ACS). May be used in the treatment of primary hypercholesterolemia and mixed dyslipidemia, homozygous familial hypercholesterolemia, primary dysbetalipoproteinemia, and/or hypertriglyeridemia as an adjunct to dietary therapy to decrease serum total and low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB), and triglyceride concentrations, while increasing high-density lipoprotein cholesterol (HDL-C) levels. | View | |
| 142 | DB00190(Carbidopa) | For treatment of the symptoms of idiopathic Parkinson's disease (paralysis agitans), post-encephalitic parkinsonism | View | |
| 15M | DB00905(Bimatoprost) | For the reduction of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication. | View | |
| 15U | DB00278(Argatroban) | Argatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention. | View | |
| 198 | DB01128(Bicalutamide) | For treatment (together with surgery or LHRH analogue) of advanced prostatic cancer. | View | |
| 1E8 | DB09053(Ibrutinib) | Ibrutinib acquired an accelerated approval for the treatment of mantle cell lymphoma who have received at least one prior therapy.[FDA label] Mantle cell lymphoma (MCL) is a B-cell non-Hodgkin lymphoma that develops in the outer edge of a lymph node. MCL is usually diagnosed at late stages and it is easily spread into bone marrow, spleen, liver and gastrointestinal tract.[L1929] | View | |
| 1FL | DB00861(Diflunisal) | For symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis. | View | |
| 1GN | DB01296(Glucosamine) | Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question. | View | |
| 1KX | DB01048(Abacavir) | For the treatment of HIV-1 infection, in combination with other antiretroviral agents. | View | |
| 1LD | DB01099(Flucytosine) | For the treatment (in combination with amphotericin B) of serious infections caused by susceptible strains of Candida (septicemia, endocarditis and urinary system infections) and/or Cryptococcus (meningitis and pulmonary infections). | View | |
| 1N1 | DB01254(Dasatinib) | For the treatment of adults with chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia with resistance or intolerance to prior therapy. Also indicated for the treatment of adults with Philadelphia chromosome-positive acute lymphoblastic leukemia with resistance or intolerance to prior therapy. | View | |
| 1PC | DB03575(Phencyclidine) | View | ||
| 1PQ | DB01087(Primaquine) | For the treatment of malaria. | View | |
| 1UN | DB00220(Nelfinavir) | Used in combination with other antiviral drugs in the treatment of HIV in both adults and children. | View | |
| 1WE | DB00182(Amphetamine);DB01576(Dextroamphetamine) | For treatment of Attention Deficit Disorder with Hyperactivity (ADDH), narcolepsy, and exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction for patients refractory to alternative therapy.;Used to treat attention deficit hyperactivity disorder (ADHD). | View | |
| 1X9 | DB01034(Cerulenin) | For use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals | View | |
| 1YN | DB01167(Itraconazole) | For the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis. | View | |
| 20J | DB01119(Diazoxide) | Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma. | View | |
| 210 | DB00282(Pamidronate) | For the treatment of moderate or severe hypercalcemia associated with malignancy | View | |
| 212 | DB00630(Alendronic acid) | For the treatment and prevention of osteoporosis in women and Paget's disease of bone in both men and women. | View | |
| 21B | DB00540(Nortriptyline) | Primarily indicated for the relief of symptoms of depression. | View | |
| 225 | DB01023(Felodipine) | For the treatment of mild to moderate essential hypertension. | View | |
| 27R | DB00963(Bromfenac) | For the treatment of postoperative inflammation in patients who have undergone cataract extraction. | View | |
| 29E | DB00476(Duloxetine) | For the acute and maintenance treatment of major depressive disorder (MDD), as well as acute management of generalized anxiety disorder. Also used for the management of neuropathic pain associated with diabetic peripheral neuropathy, and fibromyalgia. Has been used in the management of moderate to severe stress urinary incontinence (SUI) in women. | View | |
| 29J | DB06700(Desvenlafaxine) | Desvenlafaxine is indicated for the treatment of major depressive disorder in adults. | View | |
| 29Q | DB00579(Mazindol) | Used in short-term (a few weeks) treatment of exogenous obesity in conjunction with a regimen of weight reduction based on caloric restriction, exercise, and behavior modification in patients with a body mass index of 30 kg of body weight per height in meters squared (kg/m<sup>2</sup>) or in patients with a body mass index of 27 kg/m<sup>2</sup> in the presence of risk factors such as hypertension, diabetes, or hyperlipidemia. | View | |
| 29S | DB06401(Bazedoxifene) | Investigated for use/treatment in osteoporosis and menopause. | View | |
| 2C0 | DB00181(Baclofen) | For the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. | View | |
| 2DI | DB00900(Didanosine) | For use, in combination with other antiretroviral agents, in the treatment of HIV-1 infection in adults. | View | |
| 2FA | DB01073(Fludarabine) | For the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen | View | |
| 2GM | DB00320(Dihydroergotamine) | For the acute treatment of migraine headaches with or without aura and the acute treatment of cluster headache episodes. | View | |
| 2PM | DB01075(Diphenhydramine) | For the treatment of symptoms associated with Vertigo/Meniere's disease, nausea and vomiting, motion sickness and insect bite. | View | |
| 2PP | DB00313(Valproic Acid) | For treatment and management of seizure disorders, mania, and prophylactic treatment of migraine headache. In epileptics, valproic acid is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome. | View | |
| 2TN | DB00335(Atenolol) | For the management of hypertention and long-term management of patients with angina pectoris | View | |
| 2UO | DB06693(Mevastatin) | Not used therapeutically due to its many side effects. | View | |
| 308 | DB00915(Amantadine) | For the chemoprophylaxis, prophylaxis, and treatment of signs and symptoms of infection caused by various strains of influenza A virus. Also for the treatment of parkinsonism and drug-induced extrapyramidal reactions. | View | |
| 30B | DB06290(Simeprevir) | Indicated for the treatment of adults with chronic hepatitis C virus (HCV) infection: typically in combination with sofosbuvir in patients with HCV genotype 1 without cirrhosis or with compensated cirrhosis and in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis. | View | |
| 30Z | DB00179(Masoprocol) | Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated). | View | |
| 356 | DB08882(Linagliptin) | Linagliptin is used for the management of type 2 diabetes mellitus. | View | |
| 377 | DB01043(Memantine) | For the treatment of moderate to severe dementia of the Alzheimer's type. | View | |
| 37T | DB01412(Theobromine) | theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. | View | |
| 3CJ | DB00550(Propylthiouracil) | Used to manage hyperthyroidism which is due to an overactive thyroid gland (Grave's disease). | View | |
| 3QB | DB01627(Lincomycin) | Lincomycin is an antibiotic used in the treatment of staphylococcal, streptococcal, and <i>Bacteroides fragilis</i> infections. | View | |
| 3TC | DB00709(Lamivudine) | For the treatment of HIV infection and chronic hepatitis B (HBV). | View | |
| 3WF | DB00977(Ethinyl Estradiol) | For treatment of moderate to severe vasomotor symptoms associated with the menopause, female hypogonadism, prostatic carcinoma-palliative therapy of advanced disease, breast cancer, as an oral contraceptive, and as emergency contraceptive. | View | |
| 40L | DB09054(Idelalisib) | Idelalisib is indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other co-morbidities, while in the treatment of FL and SLL it is intended to be used in patients who have received at least two prior systemic therapies. | View | |
| 41X | DB00234(Reboxetine) | For the treatment of clinical depression. | View | |
| 478 | DB00701(Amprenavir) | For the treatment of HIV-1 infection in combination with other antiretroviral agents. | View | |
| 486 | DB00834(Mifepristone) | For the medical termination of intrauterine pregnancy through 49 days' pregnancy. Also indicated to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and are not candidates for surgery or have had unsuccessful surgery. | View | |
| 4AP | DB06637(Dalfampridine) | Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS). | View | |
| 4AX | DB00260(Cycloserine) | Used in combination with up to 5 other drugs as a treatment for Mycobacterium avium complex (MAC) and is also used to treat tuberculosis (TB). | View | |
| 4CH | DB13154(Parachlorophenol) | Used as an intermediate in organic synthesis of dyes and drugs. Local antibacterial agent in root canal therapy, as topical antiseptic in ointments | View | |
| 4DY | DB06774(Capsaicin) | The capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain. | View | |
| 4KO | DB00274(Cefmetazole) | For the treatment of infections caused by susceptible organisms. | View | |
| 4LE | DB00753(Isoflurane) | For induction and maintenance of general anesthesia. | View | |
| 4MK | DB09063(Ceritinib) | Ceritinib is a kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. This indication is approved under accelerated approval based on tumor response rate and duration of response. An improvement in survival or disease-related symptoms has not been established. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. | View | |
| 4PZ | DB01213(Fomepizole) | Antizol is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysis | View | |
| 4TX | DB01241(Gemfibrozil) | For treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet. | View | |
| 4YH | DB00661(Verapamil) | For the treatment of hypertension, angina, and cluster headache prophylaxis. | View | |
| 505 | DB00379(Mexiletine) | For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation. | View | |
| 51G | DB00798(Gentamicin) | For treatment of serious infections caused by susceptible strains of the following microorganisms: <i>P. aeruginosa</i>, <i>Proteus</i> species (indole-positive and indole-negative), <i>E. coli</i>, <i>Klebsiella-Enterobactor-Serratia</i> species, <i>Citrobacter</i> species and <i>Staphylococcus</i> species (coagulase-positive and coagulase-negative). | View | |
| 5AE | DB00928(Azacitidine) | For treatment of patients with the following French-American-British myelodysplastic syndrome subtypes: refractory anemia or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts, refractory anemia with excess blasts in transformation (now classified as acute myelogenous leukemia with multilineage dysplasia), and chronic myelomonocytic leukemia. | View | |
| 5CH | DB01628(Etoricoxib) | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. | View | |
| 5D5 | DB08834(Tauroursodeoxycholic acid) | Used in the treatment of cholesterol gallstones. Tauroursodeoxycholic acid is also being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis. | View | |
| 5FW | DB01064(Isoprenaline) | For the treatment of mild or transient episodes of heart block that do not require electric shock or pacemaker therapy also used in management of asthma and chronic bronchitis | View | |
| 5OG | DB05015(Belinostat) | Belinostat is indicated for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL) with manageable safety profile. It is a potential alternative therapy for patients who did not experience adequate response to first-line drugs for PTCL. It can be used in patients with baseline thrombocytopenia [A19161]. | View | |
| 657 | DB00740(Riluzole) | For the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's Disease) | View | |
| 65B | DB06414(Etravirine) | Indicated as an adjunct therapy in the treatment of adult HIV-1 infections resistant to therapy with other NNRTIs and antiretroviral agents. | View | |
| 68H | DB01001(Salbutamol);DB13139(Levosalbutamol) | For symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, and other chronic bronchopulmonary disorders such as COPD. ;Levosalbutamol's bronchodilator properties give it indications in treatment of COPD (chronic obstructive pulmonary disease, also known as chronic obstructive lung disease) and asthma. | View | |
| 68P | DB00215(Citalopram);DB01175(Escitalopram) | For the treatment of depression. Off-label indications include: treatment of mild dementia-associated agitation in nonpsychotic patients, smoking cessation, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label]. ;Labeled indications include major depressive disorder (MDD) and generalized anxiety disorder (GAD). Unlabeled indications include treatment of mild dementia-associated agitation in nonpsychotic patients. | View | |
| 6EL | DB01041(Thalidomide) | For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. | View | |
| 6J3 | DB09218(Clonixin) | Used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. | View | |
| 6JP | DB01094(Hesperetin) | For lowering cholesterol and, possibly, otherwise favorably affecting lipids. <i>In vitro</i> research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase activity, as well as activity again. | View | |
| 6K9 | DB08871(Eribulin) | For the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic cancer. | View | |
| 6LH | DB06795(Mafenide) | Mafenide is indicated in the treatment of severe burns. | View | |
| 6T0 | DB00724(Imiquimod) | For the topical treatment of clinically typical, nonhyperkeratotic, nonhypertrophic actinic keratoses on the face or scalp in immunocompetent adults. Also indicated for the treatment of external genital and perianal warts/condyloma acuminata in individuals 12 years old and above. | View | |
| 6U9 | DB00393(Nimodipine) | For use as an adjunct to improve neurologic outcome following subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms by reducing the incidence and severity of ischemic deficits. | View | |
| 6UB | DB00381(Amlodipine) | For the treatment of hypertension and chronic stable angina. | View | |
| 6V8 | DB09570(Ixazomib) | Ixazomib is indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy. | View | |
| 6ZP | DB08883(Perampanel) | Used in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures. | View | |
| 6ZZ | DB11730(Ribociclib) | Kisqali (ribociclib) is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins, when over-activated, can enable cancer cells to grow and divide too quickly. Targeting CDK4/6 with enhanced precision may play a role in ensuring that cancer cells do not continue to replicate uncontrollably. | View | |
| 715 | DB01261(Sitagliptin) | For use as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Also for use in patients with type 2 diabetes mellitus to improve glycemic control in combination with metformin or a PPARγ agonist (e.g., thiazolidinediones) when the single agent alone, with diet and exercise, does not provide adequate glycemic control. | View | |
| 7V7 | DB00813(Fentanyl) | For the treatment of cancer patients with severe pain that breaks through their regular narcotic therapy. | View | |
| 803 | DB00227(Lovastatin) | For management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease. | View | |
| 84G | DB06696(Arbekacin) | Arbekacin is used for the short term treatment of multi-resistant bacterial infections, such as methicillin-resistant <i>Staphylococcus aureus</i> (MRSA). | View | |
| 8CV | DB00914(Phenformin) | For the reatment of type II diabetes mellitus. | View | |
| 8LX | DB09198(Lobeglitazone) | Lobeglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. As an agonist for both PPARα and PPARγ, it works as an insulin sensitizer by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It was approved by the Ministry of Food and Drug Safety (Korea) in 2013, and the postmarketing surveillance is on progress until 2019. | View | |
| 8MO | DB00553(Methoxsalen) | For the treatment of psoriasis and vitiligo | View | |
| 8N6 | DB01132(Pioglitazone) | Pioglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [FDA Label]. | View | |
| 8NU | DB00734(Risperidone) | For the treatment of schizophrenia in adults and in adolescents, ages 13 to 17, and for the short-term treatment of manic or mixed episodes of bipolar I disorder in children and adolescents ages 10 to 17. May also be used to manage symptoms of inappropriate behavior due to aggression and/or psychosis in patients with severe dementia. | View | |
| 8PR | DB00715(Paroxetine) | Labeled indications include: major depressive disorder (MDD), panic disorder with or without agoraphobia, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Unlabeled indications include: eating disorders, impulse control disorders, vasomotor symptoms of menopause, obsessive-compulsive disorder (OCD) in children, and mild dementia-associated agitation in nonpsychotic individuals. Brisdelle, which consists of paroxetine mesylate is indicated for the treatment of moderate to severe vasomotor symptoms (like hot flashes) associated with menopause. | View | |
| 8QP | DB00749(Etodolac) | For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain. | View | |
| 8QS | DB00749(Etodolac) | For acute and long-term management of signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as for the management of pain. | View | |
| 8W5 | DB01222(Budesonide) | The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. | View | |
| 95E | DB00330(Ethambutol) | For use, as an adjunct, in the treatment of pulmonary tuberculosis. | View | |
| 95Z | DB01296(Glucosamine) | Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question. | View | |
| 9CR | DB00523(Alitretinoin) | For topical treatment of cutaneous lesions in patients with AIDS-related Kaposi's sarcoma. | View | |
| 9DC | DB06782(Dimercaprol) | For the treatment of arsenic, gold and mercury poisoning. Indicated in acute lead poisoning when used concomitantly with edetate calcium disodium (DB00974). | View | |
| 9F2 | DB01212(Ceftriaxone) | For the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph | View | |
| 9KL | DB09214(Dexketoprofen) | For short-term treatment of mild to moderate pain, including dysmenorrhoea. | View | |
| 9PL | DB01085(Pilocarpine) | For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome. | View | |
| 9RA | DB00307(Bexarotene) | Used orally for the treatment of skin manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. Also used topically for the treatment of skin lesions in early (stage IA and IB) CTCL in patients who experience refractory or persistent disease with the use of other therapies or are intolerant of other therapies. | View | |
| 9SC | DB01238(Aripiprazole) | For the treatment of schizophrenia and related psychotic disorders. | View | |
| 9TP | DB00444(Teniposide) | Teniposide is used for the treatment of refractory acute lymphoblastic leukaemia | View | |
| 9UQ | DB00357(Aminoglutethimide) | For the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast. | View | |
| 9V2 | DB00593(Ethosuximide) | For the treatment of petit mal epilepsy. | View | |
| 9WT | DB01413(Cefepime) | For the treatment of pneumonia (moderate to severe) caused by <i>Streptococcus pneumoniae</i>, including cases associated with concurrent bacteremia, <i>Pseudomonas aeruginosa</i>, <i>Klebsiella pneumoniae</i>, or <i>Enterobacter</i> species. Also for empiric treatment of febrile neutropenic patients and uncomplicated and complicated urinary tract infections (including pyelonephritis) caused by <i>Escherichia coli</i> or <i>Klebsiella pneumoniae</i>, when the infection is severe, or caused by <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, or <i>Proteus mirabilis</i>, when the infection is mild to moderate, including cases associated with concurrent bacteremia with these microorganisms. Also for the treatment of uncomplicated skin and skin structure infections caused by <i>Staphylococcus aureus</i> (methicillin-susceptible strains only) or <i>Streptococcus pyogenes</i> and complicated intra-abdominal infections (used in combination with metronidazole) caused by <i>Escherichia coli</i>, viridans group streptococci, <i>Pseudomonas aeruginosa</i>, <i>Klebsiella pneumoniae</i>, <i>Enterobacter</i> species, or <i>Bacteroides fragilis</i>. | View | |
| A80 | DB04942(Tamibarotene) | Investigated for use/treatment in leukemia (unspecified). | View | |
| AB1 | DB01601(Lopinavir) | Indicated in combination with other antiretroviral agents for the treatment of HIV-infection. | View | |
| AC2 | DB00787(Aciclovir) | View | ||
| ACA | DB00513(Aminocaproic Acid) | For use in the treatment of excessive postoperative bleeding. | View | |
| ACH | DB03128(Acetylcholine) | Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required. | View | |
| ACR | DB00284(Acarbose) | For treatment and management of diabetes type II (used in combination therapy as a second or third line agent) | View | |
| ACT | DB03166(Acetic acid) | Used to treat infections in the ear canal. | View | |
| ADN | DB00640(Adenosine) | Used as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST), including that associated with accessory bypass tracts, and is a drug of choice for terminating stable, narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately, as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined, stable, narrow-complex SVT. | View | |
| AEG | DB09352(Hydroxyamphetamine) | Mydriatic agent (eye pupil dilatation) for diagnosis of ophthalmic nerve lesions. | View | |
| AER | DB05812(Abiraterone) | Used in combination with prednisone for the treatment of metastatic, castration-resistant prostate cancer. | View | |
| AG2 | DB08838(Agmatine) | Agmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety, schizophrenia, and cognition). As an investigational drug, agamatine is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy. | View | |
| AGG | DB00775(Tirofiban) | For treatment, in combination with heparin, of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy. | View | |
| AIC | DB00415(Ampicillin) | For treatment of infection (Respiratory, GI, UTI and meningitis) due to E. coli, P. mirabilis, enterococci, Shigella, S. typhosa and other Salmonella, nonpenicillinase-producing N. gononhoeae, H. influenzae, staphylococci, streptococci including streptoc | View | |
| AIN | DB00945(Acetylsalicylic acid) | For use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris. | View | |
| AKN | DB00479(Amikacin) | For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species. Amikacin may also be used to treat Mycobacterium avium and Mycobacterium tuberculosis infections. | View | |
| ALE | DB00668(Epinephrine) | Used to treat anaphylaxis and sepsis. Also one of the body's main adrenergic neurotransmitters. | View | |
| AM2 | DB04626(Apramycin) | For the treatment of bacterial infections in animals. | View | |
| AMH | DB00302(Tranexamic Acid) | For use in patients with hemophilia for short term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. It can also be used for excessive bleeding in menstruation, surgery, or trauma cases. | View | |
| AMJ | DB06218(Lacosamide) | Lacosamide is indicated for adjunctive therapy for partial onset seizures in patients with epilepsy over 17 years old. Injection is indicated for short term use when oral therapy is not feasible. | View | |
| AMR | DB00594(Amiloride) | For use as adjunctive treatment with thiazide diuretics or other kaliuretic-diuretic agents in congestive heart failure or hypertension. | View | |
| ANW | DB01025(Amlexanox) | Used as a paste in the mouth to treat aphthous ulcers (canker sores). | View | |
| AOQ | DB01117(Atovaquone) | For the treatment or prevention of <i>Pneumocystis carinii</i> pneumonia in patients who are intolerant to trimethoprim-sulfamethoxazole (TMP-SMX). Also indicated for the acute oral treatment of mild to moderate PCP in patients who are intolerant to TMP-SMX. | View | |
| AQ4 | DB00530(Erlotinib) | For the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of at least one prior chemotherapy regimen. Also for use, in combination with gemcitabine, as the first-line treatment of patients with locally advanced, unresectable or metastatic pancreatic cancer. | View | |
| AR3 | DB00987(Cytarabine) | For the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia. | View | |
| ASC | DB00126(Vitamin C) | Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent. | View | |
| ASD | DB01536(4-Androstenedione) | View | ||
| ASR | DB03006(Arsanilic acid) | An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] | View | |
| ASW | DB00276(Amsacrine) | For treatment of acute myeloid leukaemia. | View | |
| AVL | DB05266(Ibudilast) | For the treatment of multiple sclerosis, asthma, and cerebrovascular disease. | View | |
| AWY | DB06594(Agomelatine) | Agomelatine is indicated for the treatment of major depressive episodes in adults. | View | |
| AXI | DB06626(Axitinib) | Used in kidney cell cancer and investigated for use/treatment in pancreatic and thyroid cancer. | View | |
| AY6 | DB06155(Rimonabant) | For use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m<sup>2</sup>, or patients wih a BMI greater than 27 kg/m<sup>2</sup> with associated risk factors, such as type 2 diabetes or dyslipidaemia. | View | |
| AZ1 | DB00548(Azelaic Acid) | For the topical treatment of mild-to-moderate inflammatory acne vulgaris. | View | |
| AZM | DB00819(Acetazolamide) | For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma | View | |
| AZZ | DB00495(Zidovudine) | Used in combination with other antiretroviral agents for the treatment of human immunovirus (HIV) infections. | View | |
| B40 | DB01577(Methamphetamine) | For the treatment of Attention Deficit Disorder with Hyperactivity (ADHD) and exogenous obesity. | View | |
| B41 | DB01454(3,4-Methylenedioxymethamphetamine) | View | ||
| B49 | DB01268(Sunitinib) | For the treatment of advanced renal cell carcinoma as well as the treatment of gastrointestinal stromal tumor after disease progression on or intolerance to imatinib mesylate. | View | |
| BAX | DB00398(Sorafenib) | Sorafenib is indicated for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinoma. | View | |
| BBI | DB01118(Amiodarone) | Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia. | View | |
| BCZ | DB06614(Peramivir) | Investigated for use/treatment in influenza. | View | |
| BEP | DB01244(Bepridil) | For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). | View | |
| BEZ | DB03793(Benzoic Acid) | A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads to excretion of these amino acids and a decrease in ammonia levels. Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia. Total Positive and Negative Syndrome Scale scores dropped by 21% compared to placebo. | View | |
| BFQ | DB00710(Ibandronate) | For the treatment and prevention of osteoporosis in postmenopausal women. | View | |
| BHA | DB00233(Aminosalicylic Acid) | For the treatment of tuberculosis | View | |
| BHS | DB00360(Sapropterin) | For the treatment of tetrahydrobiopterin (BH4) deficiency. | View | |
| BJM | DB06335(Saxagliptin) | Treatment of type 2 diabetes mellitus to improve glycemic control in combination with other agents or as monotherapy. | View | |
| BL1 | DB00808(Indapamide) | For the treatment of hypertension, alone or in combination with other antihypertensive drugs, as well as for the treatment of salt and fluid retention associated with congestive heart failure or edema from pregnancy (appropriate only in the management of edema of pathologic origin during pregnancy when clearly needed). Also used for the management of edema as a result of various causes. | View | |
| BO2 | DB00188(Bortezomib) | For treatment of multiple myeloma in patients who have not been successfully treated with at least two previous therapies. | View | |
| BQ1 | DB08903(Bedaquiline) | Bedaquiline is indicated as part of combination therapy in adults (≥ 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB). | View | |
| BRL | DB00412(Rosiglitazone) | Rosiglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | View | |
| BUW | DB00392(Ethopropazine) | For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine. | View | |
| BZ1 | DB01194(Brinzolamide) | For the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. | View | |
| BZM | DB00676(Benzyl Benzoate) | Used to kill lice and the mites responsible for the skin condition scabies. | View | |
| C04 | DB00671(Cefixime) | For use in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: (1) uncomplicated urinary tract infections caused by <i>Escherichia coli</i> and <i>Proteus mirabilis</i>, (2) otitis media caused by <i>Haemophilus influenzae</i> (beta-lactamase positive and negative strains), <i>Moraxella catarrhalis</i> (most of which are beta-lactamase positive), and <i>S. pyogenes</i>, (3) pharyngitis and tonsillitis caused by <i>S. pyogenes</i>, (4) acute bronchitis and acute exacerbations of chronic bronchitis caused by <i>Streptococcus pneumoniae</i> and <i>Haemophilus influenzae</i> (beta-lactamase positive and negative strains), and (5) uncomplicated gonorrhea (cervical/urethral) caused by <i>Neisseria gonorrhoeae</i> (penicillinase- and non-penicillinase-producing strains). | View | |
| C2F | DB11256(Levomefolic acid) | Treatment and prevention of folate deficiency Antidote against folic acid antagonists | View | |
| C3D | DB06202(Lasofoxifene) | Investigated for use/treatment in osteoporosis and female hormonal deficiencies/abnormalities. | View | |
| C41 | DB09026(Aliskiren) | For the treatment of hypertension, to lower blood pressure. | View | |
| C5E | DB09028(Cytisine) | Indicated for use in smoking cessation. | View | |
| C7H | DB00434(Cyproheptadine) | For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine. | View | |
| CA4 | DB04839(Cyproterone acetate) | For the palliative treatment of patients with advanced prostatic carcinoma. | View | |
| CAM | DB01744(Camphor) | A bicyclic monoterpene ketone found widely in plants, especially cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. [PubChem] | View | |
| CBL | DB00291(Chlorambucil) | For treatment of chronic lymphatic (lymphocytic) leukemia, childhood minimal-change nephrotic syndrome, and malignant lymphomas including lymphosarcoma, giant follicular lymphoma, Hodgkin's disease, non-Hodgkin's lymphomas, and Waldenström’s Macroglobulinemia. | View | |
| CCS | DB04339(Carbocisteine) | Used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis. | View | |
| CDX | DB00380(Dexrazoxane) | For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin hydrochloride dose of 300 mg/m^2 and would benefit from continued doxorubicin therapy. Also approved for the treatment of extravasation from intravenous anthracyclines. | View | |
| CE3 | DB00493(Cefotaxime) | Used to treat gonorrhoea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery. | View | |
| CE9 | DB06811(Polidocanol) | Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins and uncomplicated reticular veins in the lower extremity. | View | |
| CED | DB04133(Degraded Cephaloridine) | View | ||
| CEL | DB00482(Celecoxib) | For the relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis [FDA label]. | View | |
| CFB | DB00631(Clofarabine) | For the treatment of pediatric patients 1 to 21 years old with relapsed or refractory acute lymphocytic (lymphoblastic) leukemia after at least two prior regimens. It is designated as an orphan drug by the FDA for this use. | View | |
| CFF | DB00201(Caffeine) | For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants. | View | |
| CFX | DB01331(Cefoxitin) | For the treatment of serious infections caused by susceptible strains microorganisms. | View | |
| CGE | DB00758(Clopidogrel) | For the reduction of atherosclerotic events (myocardial infarction, stroke, and vascular death) in patients with atherosclerosis documented by recent stroke, recent myocardial infarction, or established peripheral arterial disease. | View | |
| CHC | DB05990(Obeticholic acid) | Investigated for use/treatment in liver disease. | View | |
| CHD | DB02659(Cholic Acid) | Oral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea or complications from decreased fat soluble vitamin absorption. | View | |
| CIA | DB00820(Tadalafil) | Used for the treatment of erectile dysfunction. | View | |
| CIL | DB01597(Cilastatin) | Combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. | View | |
| CIO | DB03849(Cilomilast) | Investigated for use/treatment in chronic obstructive pulmonary disease (COPD). | View | |
| CL6 | DB00257(Clotrimazole) | For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch. | View | |
| CL9 | DB00242(Cladribine) | For the treatment of active hairy cell leukemia (leukemic reticuloendotheliosis) as defined by clinically significant anemia, neutropenia, thrombocytopenia, or disease-related symptoms. Also used as an alternative agent for the treatment of chronic lymphocytic leukemia (CLL), low-grade non-Hodgkin's lymphoma, and cutaneous T-cell lymphoma. | View | |
| CLM | DB00446(Chloramphenicol) | Used in treatment of cholera, as it destroys the vibrios and decreases the diarrhea. It is effective against tetracycline-resistant vibrios. It is also used in eye drops or ointment to treat bacterial conjunctivitis. | View | |
| CLQ | DB00608(Chloroquine) | For the suppressive treatment and for acute attacks of malaria due to P. vivax, P.malariae, P. ovale, and susceptible strains of P. falciparum, Second-line agent in treatment of Rheumatoid Arthritis | View | |
| CLS | DB00456(Cefalotin) | Used to prevent infection during surgery and to treat many kinds of infections of the blood, bone or joints, respiratory tract, skin, and urinary tract. | View | |
| CLU | DB00575(Clonidine) | May be used as an adjunct in the treatment of hypertension, as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone, for differential diagnosis of pheochromocytoma in hypertensive patients, prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD). | View | |
| CLW | DB00356(Chlorzoxazone) | For the relief of discomfort associated with acute painful musculoskeletal conditions. | View | |
| CLY | DB01190(Clindamycin) | For the treatment of serious infections caused by susceptible anaerobic bacteria, including Bacteroides spp., Peptostreptococcus, anaerobic streptococci, Clostridium spp., and microaerophilic streptococci. May be useful in polymicrobic infections such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, aspiration pneumonia and dental infections. May also be used to treat MSSA and respiratory infections caused by S. pneumoniae and S. pyogenes in patients who are intolerant to other indicated antibiotics or who are infected with resistant organism. May be used vaginally to treat vaginosis caused by Gardnerella vaginosa. Clindamycin reduces the toxin producing effects of S. aureus and S. pyogenes and as such, may be particularly useful for treating necrotizing fasciitis. May be used topically to treat acne. | View | |
| COC | DB00907(Cocaine) | For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities. | View | |
| COX | DB00580(Valdecoxib) | For the treatment of osteoarthritis and dysmenorrhoea | View | |
| CP0 | DB00762(Irinotecan) | For the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combination with cisplatin for the treatment of extensive small cell lung cancer. Irinotecan is currently under investigation for the treatment of metastatic or recurrent cervical cancer. Also used in combination with fluorouracil and leucovorin for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. | View | |
| CP6 | DB00205(Pyrimethamine) | For the treatment of toxoplasmosis and acute malaria; For the prevention of malaria in areas non-resistant to pyrimethamine | View | |
| CPF | DB00537(Ciprofloxacin) | For the treatment of the following infections caused by susceptible organisms: urinary tract infections, acute uncomplicated cystitis, chronic bacterial prostatitis, lower respiratory tract infections, acute sinusitis, skin and skin structure infections, bone and joint infections, complicated intra-abdominal infections (used in combination with metronidazole), infectious diarrhea, typhoid fever (enteric fever), uncomplicated cervical and urethral gonorrhea, and inhalational anthrax (post-exposure). | View | |
| CQA | DB00613(Amodiaquine) | For treatment of acute malarial attacks in non-immune subjects. | View | |
| CQL | DB04815(Clioquinol) | Used as a topical antifungal treatment. | View | |
| CQN | DB01244(Bepridil) | For the treatment of hypertension, and chronic stable angina (classic effort-associated angina). | View | |
| CRN | DB00148(Creatine) | For nutritional supplementation, also for treating dietary shortage or imbalance. | View | |
| CSC | DB03313(Cephalosporin C) | View | ||
| CTC | DB09093(Chlortetracycline) | Chlortetracycline is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered in 1945 by Benjamin Minge Duggar working at Lederle Laboratories under the supervision of Yellapragada Subbarow. Duggar identified the antibiotic as the product of an actinomycete he cultured from a soil sample collected from Sanborn Field at the University of Missouri. The organism was named Streptomyces aureofaciens and the isolated drug, Aureomycin, because of their golden color. | View | |
| CTX | DB00675(Tamoxifen) | Tamoxifen is indicated for the treatment of metastatic breast cancer in women and men and ductal carcinoma in Situ. | View | |
| CTY | DB01211(Clarithromycin) | An alternative medication for the treatment of acute otitis media caused by <i>H. influenzae, M. catarrhalis, or S. pneumoniae</i> in patients with a history of type I penicillin hypersensitivity. Also for the treatment of pharyngitis and tonsillitis caused by susceptible <i>Streptococcus pyogenes</i>, as well as respiratory tract infections including acute maxillary sinusitis, acute bacterial exacerbations of chronic bronchitis, mild to moderate community-acquired pneuomia, Legionnaires' disease, and pertussis. Other indications include treatment of uncomplicated skin or skin structure infections, helicobacter pylori infection, duodenal ulcer disease, bartonella infections, early Lyme disease, and encephalitis caused by <i>Toxoplasma gondii</i> (in HIV infected patients in conjunction with pyrimethamine). Clarithromycin may also decrease the incidence of cryptosporidiosis, prevent the occurence of α-hemolytic (viridans group) streptococcal endocarditis, as well as serve as a primary prevention for <i>Mycobacterium avium</i> complex (MAC) bacteremia or disseminated infections (in adults, adolescents, and children with advanced HIV infection). | View | |
| CU9 | DB01336(Metocurine) | Metocurine is a muscle relaxant. | View | |
| CVD | DB01136(Carvedilol) | For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. | View | |
| CVI | DB00406(Gentian Violet) | For the treatment of bacterial and fungal infections inside the mouth (thrush) and skin, also for the prevention of transmission of Chagas' disease (as a blood additive). | View | |
| CWB | DB00889(Granisetron) | For the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy (including high dose cisplatin), postoperation, and radiation (including total body irradiation and daily fractionated abdominal radiation). | View | |
| CXQ | DB00245(Benzatropine) | For use as an adjunct in the therapy of all forms of parkinsonism and also for use in the control of extrapyramidal disorders due to neuroleptic drugs. | View | |
| CXX | DB01242(Clomipramine) | May be used to treat obsessive-compulsive disorder and disorders with an obsessive-compulsive component (e.g. depression, schizophrenia, Tourette’s disorder). | View | |
| CYS | DB00151(L-Cysteine) | For the prevention of liver damage and kidney damage associated with overdoses of acetaminophen | View | |
| CYZ | DB00606(Cyclothiazide) | Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. | View | |
| CZE | DB00341(Cetirizine) | For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria | View | |
| D16 | DB00293(Raltitrexed) | For the treatment of malignant neoplasm of colon and rectum | View | |
| D27 | DB07615(Tranilast) | For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | View | |
| D2V | DB00153(Ergocalciferol) | For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism, as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia, vitamin D dependent rickets, rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy, early renal osteodystrophy, osteoporosis (in conjunction with calcium), and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis). | View | |
| D7V | DB01142(Doxepin) | **Oral: ** | View | |
| D8Z | DB06697(Artemether) | Artemether and lumefantrine combination therapy is indicated for the treatment of acute uncomplicated malaria caused by <i>Plasmodium falciparum</i>, including malaria acquired in chloroquine-resistant areas. May also be used to treat uncomplicated malaria when the <i>Plasmodium</i> species has not been identified. Indicated for use in adults and children greater than 5 kg. | View | |
| D95 | DB09274(Artesunate) | For the treatment of severe malaria caused by *Plasmodium falciparum* in adults and children [L891] | View | |
| DAH | DB01235(Levodopa) | For the treatment of idiopathic Parkinson's disease (Paralysis Agitans), postencephalitic parkinsonism, symptomatic parkinsonism which may follow injury to the nervous system by carbon monoxide intoxication, and manganese intoxication. | View | |
| DB8 | DB06616(Bosutinib) | Treatment of chronic, accelerated, or blast phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) with resistance or intolerance to prior therapy in adult patients. | View | |
| DCF | DB00552(Pentostatin) | For the treatment of hairy cell leukaemia refractory to alpha interferon. | View | |
| DCK | DB00583(L-Carnitine) | For treatment of primary systemic carnitine deficiency, a genetic impairment of normal biosynthesis or utilization of levocarnitine from dietary sources, or for the treatment of secondary carnitine deficiency resulting from an inborn error of metabolism such as glutaric aciduria II, methyl malonic aciduria, propionic acidemia, and medium chain fatty acylCoA dehydrogenase deficiency. Used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. Parenteral levocarnitine is indicated for the prevention and treatment of carnitine deficiency in patients with end-stage renal disease. | View | |
| DES | DB00255(Diethylstilbestrol) | Used in the treatment of prostate cancer. Previously used in the prevention of miscarriage or premature delivery in pregnant women prone to miscarriage or premature delivery. | View | |
| DEX | DB00443(Betamethasone);DB01234(Dexamethasone) | Topical use (cream, lotion and ointment): for relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. ;<B>Injection:</B> for the treatment of endocrine disorders, rheumatic D=disorders, collagen diseases, dermatologic diseases, allergic statesc, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, cerebral edema. | View | |
| DGX | DB00390(Digoxin) | For the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. | View | |
| DHI | DB00117(L-Histidine) | The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol. | View | |
| DIF | DB00586(Diclofenac) | For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis. | View | |
| DLU | DB08930(Dolutegravir) | Dolutegravir is indicated in combination with other antiretroviral agents for the treatment of patients with HIV-1 infection that comply with the characteristics of being adults or children aged 12 years and older and present at least a weight of 40 kg.[A7520] The FDA combination therapy approval of dolutegravir and rilpivirine is indicated for adults with HIV-1 infections whose virus is currently suppressed (< 50 copies/ml) on a stable regimen for at least six months, without history of treatment failure and no known substitutions associated to resistance to any of the two components of the therapy.[L1031] | View | |
| DM1 | DB00694(Daunorubicin) | For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults. | View | |
| DM2 | DB00445(Epirubicin);DB00997(Doxorubicin) | For use as a component of adjuvant therapy in patients with evidence of axillary node tumor involvement following resection of primary breast cancer.;Doxorubicin is used to produce regression in disseminated neoplastic conditions like acute lymphoblastic leukemia, acute myeloblastic leukemia, Wilms’ tumor, neuroblastoma, soft tissue and bone sarcomas, breast carcinoma, ovarian carcinoma, transitional cell bladder carcinoma, thyroid carcinoma, gastric carcinoma, Hodgkin’s disease, malignant lymphoma and bronchogenic carcinoma in which the small cell histologic type is the most responsive compared to other cell types. Doxorubicin is also indicated for use as a component of adjuvant therapy in women with evidence of axillary lymph node involvement following resection of primary breast cancer. | View | |
| DM5 | DB01177(Idarubicin) | For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7. | View | |
| DME | DB01245(Decamethonium) | For use as a skeletal muscle relaxant | View | |
| DMO | DB06243(Eflornithine) | Eflornithine is indicated in the treatment of facial hirsutism (excessive hair growth). | View | |
| DOL | DB01764(Dalfopristin) | For the treatment of bacterial infections (usually in combination with quinupristin). | View | |
| DP0 | DB00280(Disopyramide) | For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias. It is a Class Ia antiarrhythmic drug. | View | |
| DR7 | DB01072(Atazanavir) | Used in combination with other antiretroviral agents for the treatment of HIV-1 infection, as well as postexposure prophylaxis of HIV infection in individuals who have had occupational or nonoccupational exposure to potentially infectious body fluids of a person known to be infected with HIV when that exposure represents a substantial risk for HIV transmission. | View | |
| DSF | DB01189(Desflurane) | For use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults. | View | |
| DSM | DB01151(Desipramine) | For relief of symptoms in various depressive syndromes, especially endogenous depression. It has also been used to manage chronic peripheral neuropathic pain, as a second line agent for the management of anxiety disorders (e.g. panic disorder, generalized anxiety disorder), and as a second or third line agent in the ADHD management. | View | |
| DVA | DB00161(L-Valine) | Promotes mental vigor, muscle coordination, and calm emotions. May also be of use in a minority of patients with hepatic encephalopathy and in some with phenylketonuria. | View | |
| DX2 | DB00384(Triamterene) | For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and the nephrotic syndrome; also in steroid-induced edema, idiopathic edema, and edema due to secondary hyperaldosteronism. | View | |
| DX4 | DB00352(Tioguanine) | For remission induction and remission consolidation treatment of acute nonlymphocytic leukemias. | View | |
| DXC | DB03619(Deoxycholic Acid) | For improvement in appearance of moderate to severe fullness associated with submental fat in adults. | View | |
| DXT | DB00254(Doxycycline) | Doxycycline is indicated for use in respiratory tract infections caused by Mycoplasma pneumoniae, Haemophilus influenzae, Streptococcus pneumoniae, Legionella spp., or Klebsiella spp. It is also used for prophylaxis of malaria. Doxycycline is indicated for a variety of bacterial infections, from Mycobacterium fortuitum and M. marinum, to susceptible E. coli and Brucella spp. It can be used as an alternative to treating plague, tetanus, Campylobacter fetus | View | |
| DZP | DB00829(Diazepam) | Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome. | View | |
| E20 | DB00843(Donepezil) | For the palliative treatment of mild to moderate dementia of the Alzheimer's type. | View | |
| EAA | DB00903(Etacrynic acid) | For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure. | View | |
| ECL | DB01127(Econazole) | For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by <i>Trichophyton rubrum</i>, <i>Trichophyton mentagrophytes</i>, <i>Trichophyton tonsurans</i>, <i>Microsporum canis</i>, <i>Microsporum audouini</i>, <i>Microsporum gypseum</i>, and <i>Epidermophyton floccosum</i>, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor. | View | |
| ECN | DB01127(Econazole) | For topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by <i>Trichophyton rubrum</i>, <i>Trichophyton mentagrophytes</i>, <i>Trichophyton tonsurans</i>, <i>Microsporum canis</i>, <i>Microsporum audouini</i>, <i>Microsporum gypseum</i>, and <i>Epidermophyton floccosum</i>, in the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor. | View | |
| EDP | DB00599(Thiopental) | For use as the sole anesthetic agent for brief (15 minute) procedures, for induction of anesthesia prior to administration of other anesthetic agents, to supplement regional anesthesia, to provide hypnosis during balanced anesthesia with other agents for analgesia or muscle relaxation, for the control of convulsive states during or following inhalation anesthesia or local anesthesia, in neurosurgical patients with increased intracranial pressure, and for narcoanalysis and narcosynthesis in psychiatric disorders. | View | |
| EDR | DB01010(Edrophonium) | For the differential diagnosis of myasthenia gravis and as an adjunct in the evaluation of treatment requirements in this disease. It may also be used for evaluating emergency treatment in myasthenic crises. | View | |
| EDT | DB00974(Edetic Acid) | For the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults. | View | |
| EF2 | DB01041(Thalidomide) | For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. | View | |
| EFZ | DB00625(Efavirenz) | For use in combination treatment of HIV infection (AIDS) | View | |
| ELV | DB09101(Elvitegravir) | Elvitegravir in combination with an HIV protease inhibitor coadministered with ritonavir and with other antiretroviral drug(s) is indicated for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. | View | |
| EMH | DB11363(Alectinib) | Alectinib is a kinase inhibitor indicated for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive, metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. This indication is approved under accelerated approval based on tumor response rate and duration of response. Continued approval for this indication may be contingent upon verification and description of clinical benefit in confirmatory trials. | View | |
| EPA | DB00159(Icosapent) | EPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy. | View | |
| EQI | DB02187(Equilin) | For the treatment of moderate to severe vasomotor symptoms associated with the menopause, atrophic vaginitis, osteoporosis, hypoestrogenism due to hypogonadism, castration, primary ovarian failure, breast cancer (for palliation only), and Advanced androgen-dependent carcinoma of the prostate (for palliation only) | View | |
| ERM | DB00696(Ergotamine) | For use as therapy to abort or prevent vascular headache, e.g., migraine, migraine variants, or so called "histaminic cephalalgia". | View | |
| ERY | DB00199(Erythromycin) | For use in the treatment of infections caused by susceptible strains of microorganisms in the following diseases: respiratory tract infections (upper and lower) of mild to moderate degree, pertussis (whooping cough), as adjunct to antitoxin in infections due to <i>Corynebacterium diphtheriae</i>, in the treatment of infections due to <i>Corynebacterium minutissimum</i>, intestinal amebiasis caused by <i>Entamoeba histolytica</i>, acute pelvic inflammatory disease caused by <i>Neisseria gonorrhoeae</i>, skin and soft tissue infections of mild to moderate severity caused by <i>Streptococcus pyogenes</i> and <i>Staphylococcus aureus</i>, primary syphilis caused by <i>Treponema pallidum</i>, infections caused by <i>Chlamydia trachomatis</i>, nongonococcal urethritis caused by <i>Ureaplasma urealyticum</i>, and Legionnaires' disease caused by <i>Legionella pneumophila</i>. | View | |
| ESL | DB04573(Estriol) | Used as a test to determine the general health of an unborn fetus. | View | |
| EST | DB00783(Estradiol) | Estradiol is indicated for the treatment of moderate to severe vasomotor symptoms and vulvar and vaginal atrophy due to menopause, for the treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure, and for the prevention of post-menopausal osteoarthritis. It is also used for the treatment of breast cancer (for palliation only) in appropriately selected women and men with metastatic disease, and for the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only). | View | |
| ETS | DB00869(Dorzolamide) | For the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Also used prophylatically for the inhibition of perioperative IOP increase (before neodynium yttrium aluminum garnet laser posterior capsulotomy). | View | |
| ETV | DB00879(Emtricitabine) | Indicated, in combination with other antiretroviral agents, for the treatment of HIV-1 infection in adults and for postexposure prophylaxis of HIV infection in health care workers and others exposed occupationally or nonoccupationally via percutaneous injury or mucous membrane or nonintact skin contact with blood, tissues, or other body fluids associated with risk for transmission of the virus. | View | |
| EU7 | DB00478(Rimantadine) | For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults. | View | |
| EUI | DB05239(Cobimetinib) | For the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation. Cobimetinib is used in combination with vemurafenib, a BRAF inhibitor. | View | |
| EV1 | DB01113(Papaverine) | For the treatment of impotence and vasospasms. | View | |
| EVP | DB00773(Etoposide) | For use in combination with other chemotherapeutic agents in the treatment of refractory testicular tumors and as first line treatment in patients with small cell lung cancer. Also used to treat other malignancies such as lymphoma, non-lymphocytic leukemia, and glioblastoma multiforme. | View | |
| EXM | DB00990(Exemestane) | For the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy. | View | |
| EY4 | DB11371(Alfaxalone) | Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic. It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. Along with alfadolone, it is also one of the constituents of anesthetic drug mixture althesin. | View | |
| EZL | DB00311(Ethoxzolamide) | For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. | View | |
| F9E | DB01610(Valganciclovir) | Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections. | View | |
| FCN | DB00828(Fosfomycin) | For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of <i>Escherichia coli</i> and <i>Enterococcus faecalis</i>. | View | |
| FFO | DB11596(Levoleucovorin) | Levoleucovorin is indicated for use as rescue therapy following high-dose methotrexate in the treatment of osteosarcoma or for diminishing the toxicity associated with inadvertent overdosage of folic acid antagonists. Levoleucovorin, as the product Fusilev (FDA, dosed at one-half the usual dose of racemic d,l-leucovorin), has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer (although they should not be mixed in the same infusion as a precipitate may form). | View | |
| FI8 | DB08874(Fidaxomicin) | Treatment of Clostridium difficile-associated diarrhea | View | |
| FIT | DB01216(Finasteride) | For the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate to: Improve symptoms, reduce the risk of acute urinary retention, reduce the risk of the need for surgery including transurethral resection of the prostate. Also used for the stimulation of regrowth of hair in men with mild to moderate androgenetic alopecia (male pattern alopecia, hereditary alopecia, common male baldness). | View | |
| FJQ | DB01007(Tioconazole) | For the local treatment of vulvovaginal candidiasis (moniliasis). | View | |
| FK5 | DB00864(Tacrolimus) | For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis. | View | |
| FL7 | DB00690(Flurazepam) | For short-term and intermittent use in patients with recurring insomnia and poor sleeping habits | View | |
| FLP | DB00712(Flurbiprofen) | Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis. | View | |
| FLR | DB00712(Flurbiprofen) | Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis. | View | |
| FMM | DB01259(Lapatinib) | Indicated in combination with capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress the human epidermal receptor type 2 (HER2) protein and who have received prior therapy including an anthracycline, a taxane, and trastuzuma. | View | |
| FOL | DB00158(Folic Acid) | For treatment of folic acid deficiency, megaloblastic anemia and in anemias of nutritional supplements, pregnancy, infancy, or childhood. | View | |
| FOZ | DB11596(Levoleucovorin) | Levoleucovorin is indicated for use as rescue therapy following high-dose methotrexate in the treatment of osteosarcoma or for diminishing the toxicity associated with inadvertent overdosage of folic acid antagonists. Levoleucovorin, as the product Fusilev (FDA, dosed at one-half the usual dose of racemic d,l-leucovorin), has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer (although they should not be mixed in the same infusion as a precipitate may form). | View | |
| FRD | DB00182(Amphetamine) | For treatment of Attention Deficit Disorder with Hyperactivity (ADDH), narcolepsy, and exogenous obesity as a short term (a few weeks) adjunct in a regimen of weight reduction based on caloric restriction for patients refractory to alternative therapy. | View | |
| FUA | DB02703(Fusidic Acid) | For the treatment of bacterial infections. | View | |
| FUN | DB00695(Furosemide) | For the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents. | View | |
| FVS | DB00947(Fulvestrant) | For the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. | View | |
| FVT | DB00855(Aminolevulinic acid) | Aminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp. | View | |
| FVX | DB00176(Fluvoxamine) | Indicated predominantly for the management of depression and for Obsessive Compulsive Disorder (OCD) [FDA Label]. Has also been used in the management of bulimia nervosa [A250]. | View | |
| FY5 | DB04574(Estrone sulfate) | Estropipate is used for the treatment of moderate to severe vasomotor symptoms associated with the monopause, and moderate to severe symptoms of vulval and vaginal atrophy associated with the menopause. It is also used to treat hypoestrogenism due to hypogonadism, castration or primary ovarian failure, and prevent postmenopausal osteoporosis. | View | |
| FYP | DB01205(Flumazenil) | For the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, and where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures. Also for the management of benzodiazepine overdose as an adjunct for appropriate supportive and symptomatic measures. | View | |
| GA2 | DB01004(Ganciclovir) | For induction and maintenance in the treatment of cytomegalovirus (CMV) retinitis in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). Also used in the treatment of severe cytomegalovirus (CMV) disease, including CMV pneumonia, CMV gastrointestinal disease, and disseminated CMV infections, in immunocompromised patients. | View | |
| GAI | DB00536(Guanidine) | For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis. | View | |
| GAW | DB09048(Netupitant) | Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. | View | |
| GBM | DB01016(Glyburide) | Indicated as an adjunct to diet to lower the blood glucose in patients with NIDDM whose hyperglycemia cannot be satisfactorily controlled by diet alone. | View | |
| GBN | DB00996(Gabapentin) | For the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy. | View | |
| GBQ | DB00673(Aprepitant) | For the prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy, including high-dose cisplatin (in combination with other antiemetic agents). | View | |
| GCS | DB01296(Glucosamine) | Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question. | View | |
| GEO | DB00441(Gemcitabine) | Gemcitabine is indicated for the treatment of advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy; metastatic ovarian cancer; inoperable, locally advanced (Stage IIIA or IIIB), or metastatic (Stage IV) non-small cell lung cancer; and locally advanced (nonresectable Stage II or Stage III) or metastatic (Stage IV) adenocarcinoma of the pancreas. | View | |
| GFN | DB01044(Gatifloxacin) | For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin infections (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes | View | |
| GG2 | DB06605(Apixaban) | Apixaban is to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It has also been used to lower the risk of developing venous thrombosis post-orthopedic surgical procedures. | View | |
| GJZ | DB00752(Tranylcypromine) | For the treatment of major depressive episode without melancholia. | View | |
| GLY | DB00145(Glycine) | Supplemental glycine may have antispastic activity. Very early findings suggest it may also have antipsychotic activity as well as antioxidant and anti-inflammatory activities. | View | |
| GM4 | DB00652(Pentazocine) | For the relief of moderate to severe pain. | View | |
| GMJ | DB00502(Haloperidol) | For the management of psychotic disorders (eg. schizophrenia) and delirium, as well as to control tics and vocal utterances of Tourette's syndrome (Gilles de la Tourette's syndrome). Also used for the treatment of severe behavioural problems in children with disrubtive behaviour disorder or ADHD (attention-deficit hyperactivity disorder). Haloperidol has been used in the prevention and control of severe nausea and vomiting. | View | |
| GMR | DB00222(Glimepiride) | For concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. | View | |
| GNT | DB00674(Galantamine) | For the treatment of mild to moderate dementia of the Alzheimer's type. Has also been investigated in patients with mild cognitive impairment who did not meet the diagnostic criteria for Alzheimer's disease. | View | |
| GW6 | DB08906(Fluticasone furoate) | Fluticasone furoate nasal spray is indicated for the treatment of the symptoms of seasonal and perennial allergic rhinitis in patients aged 2 years and older. | View | |
| H3P | DB00756(Hexachlorophene) | For use as a surgical scrub and a bacteriostatic skin cleanser. It may also be used to control an outbreak of gram-positive infection where other infection control procedures have been unsuccessful. | View | |
| H4B | DB00360(Sapropterin) | For the treatment of tetrahydrobiopterin (BH4) deficiency. | View | |
| H4C | DB09166(Etizolam) | Etizolam (marketed under the brand name Etilaam, Etizola, Sedekopan, Etizest, Pasaden or Depas) is a benzodiazepine analog. The etizolam molecule differs from a benzodiazepine in that the benzene ring has been replaced by a thiophene ring, making the drug a thienodiazepine. It possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Etizolam is not authorized for medical use in the U.S. However, it currently remains unscheduled and is legal for research purposes. | View | |
| H8D | DB00353(Methylergometrine) | For the prevention and control of excessive bleeding following vaginal childbirth | View | |
| H8G | DB00589(Lisuride) | For the management of Parkinson's Disease | View | |
| H8J | DB00247(Methysergide) | For the treatment of vascular headache | View | |
| H98 | DB01274(Arformoterol) | A bronchodilator used for the long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. | View | |
| HAE | DB00551(Acetohydroxamic Acid) | Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections. | View | |
| HCY | DB00741(Hydrocortisone) | For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Also used to treat endocrine (hormonal) disorders (adrenal insufficiency, Addisons disease). It is also used to treat many immune and allergic disorders, such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease. | View | |
| HCZ | DB00999(Hydrochlorothiazide) | For the treatment of high blood pressure and management of edema. | View | |
| HFG | DB04866(Halofuginone) | For the treatment of scleroderma, cancer, and restenosis. | View | |
| HFZ | DB00774(Hydroflumethiazide) | Used as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Also used in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. | View | |
| HIS | DB00117(L-Histidine) | The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol. | View | |
| HLT | DB01159(Halothane) | For the induction and maintenance of general anesthesia | View | |
| HLZ | DB01275(Hydralazine) | For the treatment of essential hypertension, alone or as an adjunct. Also for the management of severe hypertension when the drug cannot be given orally or when blood pressure must be lowered immediately, congestive heart failure (in combination with cardiac glycosides and diuretics and/or with isosorbide dinitrate), and hypertension secondary to pre-eclampsia/eclampsia. | View | |
| HNQ | DB01422(Nitroxoline) | Nitroxoline is an antibiotic agent. | View | |
| HQE | DB09526(Hydroquinone) | Hydroquinone is used as an OTC topical lightening agent for disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots and freckles. | View | |
| HSM | DB05381(Histamine) | Histamine phosphate is indicated as a diagnostic aid for evaluation of gastric acid secretory function. | View | |
| HU5 | DB08873(Boceprevir) | Boceprevir, when used in combination with [DB00811], [DB00008], and [DB00022] is indicated for use in the treatment of chronic HCV genotype 1 infection in adults [FDA Label]. | View | |
| I7A | DB01144(Diclofenamide) | For adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure | View | |
| IBP | DB01050(Ibuprofen) | For symptomatic treatment of rheumatoid arthritis, juvenile rheumatoid arthritis and osteoarthritis. May be used to treat mild to moderate pain and for the management of dysmenorrhea. May be used to reduce fever. Has been used with some success for treating ankylosing spondylitis, gout and psoriatic arthritis. May reduce pain, fever and inflammation of pericarditis. May be used IV with opiates to relieve moderate to severe pain. Ibuprofen lysine may be used IV to treat patent ductus arteriosus (PDA) in premature neonates. | View | |
| ICF | DB00753(Isoflurane) | For induction and maintenance of general anesthesia. | View | |
| ID2 | DB00249(Idoxuridine) | For use in keratoconjunctivitis and keratitis caused by herpes simplex virus. | View | |
| ID8 | DB00784(Mefenamic acid) | For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever. | View | |
| IL2 | DB01088(Iloprost) | Used for the treatment of pulmonary arterial hypertension. | View | |
| ILE | DB00167(L-Isoleucine) | The branched-chain amino acids may have antihepatic encephalopathy activity in some. They may also have anticatabolic and antitardive dyskinesia activity. | View | |
| IMN | DB00328(Indomethacin) | For moderate to severe rheumatoid arthritis including acute flares of chronic disease, ankylosing spondylitis, osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis. | View | |
| IPB | DB02513(Thymol) | A phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed) | View | |
| IPH | DB03255(Phenol) | Phenol is primarily indicated for minor sore throat pain, sore mouth, minor mouth irritation, and pain associated with canker sores. Additionally, phenol is indicated in the treatment of focal spasticity. | View | |
| IRE | DB00317(Gefitinib) | For the continued treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of either platinum-based or docetaxel chemotherapies. | View | |
| IU5 | DB01586(Ursodeoxycholic acid) | The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. | View | |
| IVM | DB00602(Ivermectin) | A broad-spectrum anti-parasite medication. It was first marketed under the name Stromectol® and used against worms (except tapeworms), but, in 2012, it was approved for the topical treatment of head lice infestations in patients 6 months of age and older, and marketed under the name Sklice™ as well. Ivermectin is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis). | View | |
| IXX | DB00458(Imipramine) | For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older [FDA Label]. | View | |
| IZP | DB01050(Ibuprofen) | For symptomatic treatment of rheumatoid arthritis, juvenile rheumatoid arthritis and osteoarthritis. May be used to treat mild to moderate pain and for the management of dysmenorrhea. May be used to reduce fever. Has been used with some success for treating ankylosing spondylitis, gout and psoriatic arthritis. May reduce pain, fever and inflammation of pericarditis. May be used IV with opiates to relieve moderate to severe pain. Ibuprofen lysine may be used IV to treat patent ductus arteriosus (PDA) in premature neonates. | View | |
| J01 | DB00766(Clavulanate) | For use with Amoxicillin, clavulanic acid is suitable for the treatment of infections with <i>Staph. aureus</i> and <i>Bacteroides fragilis</i>, or with beta-lactamase producing <i>H. influenzae</i> and <i>E. coli</i>. | View | |
| J3Z | DB00655(Estrone) | For management of perimenopausal and postmenopausal symptoms. | View | |
| JMS | DB00939(Meclofenamic acid) | For the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis. | View | |
| JN3 | DB01586(Ursodeoxycholic acid) | The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. | View | |
| JTZ | DB00866(Alprenolol) | For the treatment of hypertension, angina, and arrhythmia | View | |
| K1S | DB09283(Trapidil) | Used to treat patients with ischemic coronary heart, liver, and kidney disease. | View | |
| K4D | DB01195(Flecainide) | Flecainide is is a class Ic antiarrhythmic agent and as such, it is used for the prevention of paroxysmal supraventricular tachycardias (PSVT), including atrioventricular nodal reentrant tachycardia, atrioventricular reentrant tachycardia and other supraventricular tachycardias of unspecified mechanism associated with disablin. | View | |
| K5Y | DB00938(Salmeterol) | For the treatment of asthma and chronic obstructive pulmonary disease (COPD). | View | |
| K86 | DB00559(Bosentan) | Used in the treatment of pulmonary arterial hypertension (PAH), to improve exercise ability and to decrease the rate of clinical worsening (in patients with WHO Class III or IV symptoms). | View | |
| KAN | DB01172(Kanamycin) | For treatment of infections where one or more of the following are the known or suspected pathogens: <i>E. coli</i>, <i>Proteus</i> species (both indole-positive and indole-negative), <i>E. aerogenes, K. pneumoniae, S. marcescens,</i> and <i>Acinetobacter</i> species. | View | |
| KKK | DB01026(Ketoconazole) | For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. | View | |
| KLN | DB01026(Ketoconazole) | For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. | View | |
| KLT | DB00310(Chlorthalidone) | For management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. | View | |
| KOV | DB01112(Cefuroxime) | For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections. | View | |
| KTN | DB01026(Ketoconazole) | For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. | View | |
| KTR | DB00465(Ketorolac) | For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. | View | |
| L8P | DB00369(Cidofovir) | For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) | View | |
| LAX | DB00154(Dihomo-gamma-linolenic acid) | For nutritional supplementation, also for treating dietary shortage or imbalance | View | |
| LBH | DB06603(Panobinostat) | Panobinostat is indicated in the treatment of multiple myeloma in combination with dexamethasone and bortezomib in patients who have received 2 previous treatment regimens including bortezomib and an immunomodulatory agent. This indication is approved by accelerated approval based on progression free survival as of February 23, 2015. | View | |
| LCR | DB00341(Cetirizine);DB06282(Levocetirizine) | For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria;Levocetirizine is indicated for the relief of symptoms associated with allergic rhinitis (seasonal and perennial) in adults and children 6 years of age and older. | View | |
| LDP | DB00988(Dopamine) | For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure | View | |
| LEI | DB00859(Penicillamine) | For treatment of Wilson's disease, cystinuria and active rheumatoid arthritis. | View | |
| LEU | DB00149(L-Leucine) | Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress. | View | |
| LEV | DB09078(Lenvatinib) | Lenvatinib is indicated for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer. | View | |
| LF7 | DB04876(Vildagliptin) | Used to reduce hyperglycemia in type 2 diabetes mellitus. | View | |
| LFX | DB01137(Levofloxacin);DB01165(Ofloxacin) | For the treatment of bacterial conjunctivitis caused by susceptible strains of the following organisms: <i>Corynebacterium</i> species, <i>Staphylococus aureus</i>, <i>Staphylococcus epidermidis</i>, <i>Streptococcus pneumoniae</i>, <i>Streptococcus</i> (Groups C/F/G), Viridans group streptococci, <i>Acinetobacter lwoffii</i>, <i>Haemophilus influenzae</i>, <i>Serratia marcescens</i>.;For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea. | View | |
| LLL | DB04729(GENTAMICIN C1A) | View | ||
| LLT | DB01265(Telbivudine) | For the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease. | View | |
| LNL | DB00132(Alpha-Linolenic Acid) | For nutritional supplementation and for treating dietary shortage or imbalance. | View | |
| LNR | DB00368(Norepinephrine) | Mainly used to treat patients in vasodilatory shock states such as septic shock and neurogenic shock and has shown a survival benefit over dopamine. Also used as a vasopressor medication for patients with critical hypotension. | View | |
| LOC | DB01394(Colchicine) | For treatment and relief of pain in attacks of acute gouty arthritis. | View | |
| LPR | DB00722(Lisinopril) | For the treatment of hypertension and symptomatic congestive heart failure. May be used in conjunction with thrombolytic agents, aspirin and/or β-blockers to improve survival in hemodynamically stable individuals following myocardial infarction. May be used to slow the progression of renal disease in hypertensive patients with diabetes mellitus and microalbuminuria or overt nephropathy. | View | |
| LQQ | DB09073(Palbociclib) | Palbociclib is indicated in combination with letrozole for the treatment of postmenopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer as initial endocrine-based therapy for their metastatic disease. This indication is approved under accelerated approval based on progression-free survival (PFS). Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial. | View | |
| LQZ | DB00281(Lidocaine) | For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks. | View | |
| LSN | DB00678(Losartan) | May be used as a first line agent to treat uncomplicated hypertension, isolated systolic hypertension and left ventricular hypertrophy. May be used as a first line agent to delay progression of diabetic nephropathy. Losartan may be also used as a second line agent in the treatment of congestive heart failure, systolic dysfunction, myocardial infarction and coronary artery disease in those intolerant of ACE inhibitors. | View | |
| LUR | DB01283(Lumiracoxib) | For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults. | View | |
| LVY | DB00480(Lenalidomide) | Lenalidomide is indicated for the treatment of multiple myeloma in combination with dexamethasone. It is also indicated for the treatment of patients with transfusion-dependent anemia due to low- or intermediate- risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities. | View | |
| LYA | DB00642(Pemetrexed) | Used in combination with cisplatin for the treatment of malignant pleural mesothelioma in adults whose disease is unresectable or who otherwise are not candidates for potentially curative surgery. Also used as a monotherapy for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) after prior chemotherapy | View | |
| LZU | DB00679(Thioridazine) | For the treatment of schizophrenia and generalized anxiety disorder. | View | |
| MC9 | DB02300(Calcipotriol) | For the treatment of moderate plaque psoriasis in adults. | View | |
| MEM | DB00760(Meropenem) | For use as single agent therapy for the treatment of the following infections when caused by susceptible isolates of the designated microorganisms: <b>complicated skin and skin structure infections</b> due to <i>Staphylococcus aureus</i> (b-lactamase and non-b-lactamase producing, methicillin-susceptible isolates only), <i>Streptococcus pyogenes</i>, <i>Streptococcus agalactiae</i>, viridans group streptococci, <i>Enterococcus faecalis</i> (excluding vancomycin-resistant isolates), <i>Pseudomonas aeruginosa</i>, <i>Escherichia coli</i>, <i>Proteus mirabilis</i>, <i>Bacteroides fragilis</i> and <i>Peptostreptococcus</i> species; <b>complicated appendicitis and peritonitis</b> caused by viridans group streptococci, <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i>, <i>Pseudomonas aeruginosa</i>, <i>Bacteroides fragilis</i>, <i>B. thetaiotaomicron</i>, and <i>Peptostreptococcus</i> species. Also for use in the treatment of bacterial meningitis caused by <i>Streptococcus pneumoniae</i>, <i>Haemophilus influenzae</i> (b-lactamase and non-b-lactamase-producing isolates), and <i>Neisseria meningitidis</i>. | View | |
| MF8 | DB00331(Metformin) | For use as an adjunct to diet and exercise in adult patients (18 years and older) with NIDDM. May also be used for the management of metabolic and reproductive abnormalities associated with polycystic ovary syndrome (PCOS). Jentadueto is for the treatment of patients when both linagliptin and metformin is appropriate. | View | |
| MFX | DB00218(Moxifloxacin) | For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye). | View | |
| MI1 | DB08895(Tofacitinib) | For the treatment of moderate to severe rheumatoid arthritis which is resistant or intolerant to methotrexate therapy. It may also be used as an adjunct to methotrexate therapy, or other non-biologic disease-modifying antirheumatic drugs (DMARDS), when methotrexate alone is not sufficient. | View | |
| MIG | DB00491(Miglitol) | For use as an adjunct to diet to improve glycemic control in patients with non-insulin-dependent diabetes mellitus (NIDDM) whose hyperglycemia cannot be managed with diet alone. | View | |
| MII | DB01603(Meticillin) | Used to treat infections caused by susceptible Gram-positive bacteria, particularly beta-lactamase-producing organisms such as <i>Staphylococcus aureus</i> that would otherwise be resistant to most penicillins. | View | |
| MIL | DB00235(Milrinone) | Indicated for the treatment of congestive heart failure. | View | |
| MIT | DB00278(Argatroban) | Argatroban is indicated for prevention and treatment of thrombosis caused by heparin induced thrombocytopenia (HIT). It is also indicated for use in patients with, or at risk for, HIT who are undergoing percutaneous coronary intervention. | View | |
| MIX | DB01204(Mitoxantrone) | For the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis | View | |
| MIY | DB01017(Minocycline) | For the treatment of infections caused by susceptible strains of microorganisms, such as Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsial pox and tick fevers caused by Rickettsiae, upper respiratory tract infections caused by <i>Streptococcus pneumoniae</i> and for the treatment of asymptomatic carriers of <i>Neisseria meningitidis</i>. | View | |
| MK1 | DB00224(Indinavir) | Indinavir is an antiretroviral drug for the treatment of HIV infection. | View | |
| ML1 | DB01065(Melatonin) | Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for this use. A number of studies have shown that melatonin may be effective for treating sleep-wake cycle disturbances in children and adolescents with mental retardation, autism, and other central nervous system disorders. It appears to decrease the time to fall asleep in children with developmental disabilities, such as cerebral palsy, autism, and mental retardation. It may also improve secondary insomnia associated with various sleep-wake cycle disturbances. Other possible uses for which there is some evidence for include: benzodiazepine withdrawal, cluster headache, delayed sleep phase syndrome (DSPS), primary insomnia, jet lag, nicotine withdrawal, preoperative anxiety and sedation, prostate cancer, solid tumors (when combined with IL-2 therapy in certain cancers), sunburn prevention (topical use), tardive dyskinesia, thrombocytopenia associated with cancer, chemotherapy and other disorders. | View | |
| MMS | DB01055(Mimosine) | View | ||
| MMZ | DB00763(Methimazole) | For the treatment of hyperthyroidism, goiter, Graves disease and psoriasis. | View | |
| MN9 | DB00141(N-Acetyl-D-glucosamine) | For the treatment and prevention of osteoarthritis, by itself or in combination with chondroitin sulfate. | View | |
| MOA | DB01024(Mycophenolic acid) | For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids. | View | |
| MOI | DB00295(Morphine) | For the relief and treatment of severe pain. | View | |
| MRC | DB00410(Mupirocin) | For the treatment of <i>Staphylococci</i> nasal carriers. | View | |
| MRV | DB04835(Maraviroc) | For treatment-experienced adult patients infected with only CCR5-tropic HIV-1 detectable, who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents. | View | |
| MTK | DB00471(Montelukast) | For the treatment of asthma | View | |
| MTL | DB00742(Mannitol) | Used for the promotion of diuresis before irreversible renal failure becomes established, the reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances. | View | |
| MTX | DB00563(Methotrexate) | Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non-Hodgkin’s lymphomas. Methotrexate is indicated in the symptomatic control of severe, recalcitrant, disabling psoriasis. Methotrexate is indicated in the management of selected adults with severe, active rheumatoid arthritis (ACR criteria), or children with active polyarticular-course juvenile rheumatoid arthritis. | View | |
| MV2 | DB09357(Dexpanthenol) | Injection: Prophylactic use immediately after major abdominal surgery to minimize the possibility of paralytic ileus. Intestinal atony causing abdominal distention; postoperative or postpartum retention of flatus, or postoperative delay in resumption of intestinal motility; paralytic ileus. | View | |
| MXD | DB00350(Minoxidil) | For the treatment of severe hypertension and in the topical treatment (regrowth) of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia. | View | |
| MXM | DB00814(Meloxicam) | For symptomatic treatment of arthritis and osteoarthritis. | View | |
| MYT | DB01011(Metyrapone) | Used as a diagnostic drug for testing hypothalamic-pituitary ACTH function. Occasionally used in Cushing's syndrome. | View | |
| MZM | DB00703(Methazolamide) | For treatment of chronic open-angle glaucoma and acute angle-closure glaucoma | View | |
| NBO | DB00461(Nabumetone) | For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis. | View | |
| NBV | DB00419(Miglustat) | For the treatment of adult patients with mild to moderate type 1 (nonneuropathic) Gaucher's disease for whom enzyme replacement therapy is not a therapeutic option (e.g. due to constraints such as allergy, hypersensitivity, or poor venous access). Now approved in some countries for the treatment of progressive neurological symptoms in adult and pediatric patients with Niemann-Pick disease type C (NP-C). | View | |
| NCA | DB02701(Nicotinamide) | An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem] | View | |
| NCT | DB00184(Nicotine) | For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. | View | |
| NDR | DB00717(Norethisterone) | For the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as submucous fibroids or uterine cancer. | View | |
| NFL | DB04552(Niflumic Acid) | Used in the treatment of rheumatoid arthritis. | View | |
| NFN | DB00607(Nafcillin) | Indicated in the treatment of infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug. | View | |
| NFZ | DB00336(Nitrofural) | For the treatement of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms. | View | |
| NHY | DB01005(Hydroxyurea) | For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia. | View | |
| NIL | DB04868(Nilotinib) | For the potential treatment of various leukemias, including chronic myeloid leukemia (CML). | View | |
| NIM | DB04743(Nimesulide) | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. | View | |
| NIO | DB00627(Niacin) | For the treatment of type IV and V hyperlipidemia. It is indicated as ajunctive therapy. | View | |
| NIZ | DB00951(Isoniazid) | For the treatment of all forms of tuberculosis in which organisms are susceptible. | View | |
| NMY | DB00452(Framycetin);DB00994(Neomycin) | For the treatment of bacterial blepharitis, bacterial bonjunctivitis, corneal injuries, corneal ulcers and meibomianitis. For the prophylaxis of ocular infections following foreign body removal;Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC). | View | |
| NOG | DB00367(Levonorgestrel);DB09389(Norgestrel) | For the treatment of menopausal and postmenopausal disorders and alone or in combination with other hormones as an oral contraceptive.;Norgestrel in combination with ethinyl estradiol is indicated for the prevention of pregnancy in women who elect to use this product as a method of contraception. | View | |
| NOV | DB01051(Novobiocin) | For the treatment of infections due to staphylococci and other susceptible organisms | View | |
| NPS | DB00788(Naproxen) | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also for the relief of mild to moderate pain and the treatment of primary dysmenorrhea. | View | |
| NPU | DB00397(Phenylpropanolamine) | For the treatment of nasal congestion, control of urinary incontinence, priapism and obesity. | View | |
| NTI | DB00507(Nitazoxanide) | For the treatment of diarrhea in adults and children caused by the protozoa <i>Giardia lamblia</i>, and for the treatment of diarrhea in children caused by the protozoan, <i>Cryptosporidium parvum</i> [FDA label]. | View | |
| NVP | DB00238(Nevirapine) | For use in combination with other antiretroviral drugs in the ongoing treatment of HIV-1 infection. | View | |
| OAQ | DB01096(Oxamniquine) | For treatment of Schistosomiasis caused by <i>Schistosoma mansoni</i> | View | |
| OBN | DB01092(Ouabain) | For the treatment of atrial fibrillation and flutter and heart failure | View | |
| OHB | DB08797(Salicylamide) | Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies | View | |
| OIN | DB00424(Hyoscyamine);DB00572(Atropine) | For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease and rhinitis.;For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides. | View | |
| OLM | DB00275(Olmesartan) | For the treatment of hypertension. | View | |
| OQR | DB01096(Oxamniquine) | For treatment of Schistosomiasis caused by <i>Schistosoma mansoni</i> | View | |
| OTC | DB00595(Oxytetracycline) | Oxytetracycline is indicated for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including <i>Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae</i> (respiratory infections), and <i>Diplococcus pneumoniae</i>. | View | |
| P06 | DB08912(Dabrafenib) | Tafinlar is a kinase inhibitor that was initially indicated as a single agent for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test [FDA label]. | View | |
| P1B | DB01132(Pioglitazone) | Pioglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus [FDA Label]. | View | |
| P1Z | DB00812(Phenylbutazone) | For the treatment of backache and ankylosing spondylitis | View | |
| P2E | DB00917(Dinoprostone) | For the termination of pregnancy during the second trimester (from the 12th through the 20th gestational week as calculated from the first day of the last normal menstrual period), as well as for evacuation of the uterine contents in the management of missed abortion or intrauterine fetal death up to 28 weeks of gestational age as calculated from the first day of the last normal menstrual period. Also used in the management of nonmetastatic gestational trophoblastic disease (benign hydatidiform mole). Other indications include improving the cervical inducibility (cervical "ripening") in pregnant women at or near term with a medical or obstetrical need for labor induction, and the management of postpartum hemorrhage. | View | |
| P2Z | DB00420(Promazine) | Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly. | View | |
| P77 | DB00433(Prochlorperazine) | For the symptomatic management of psychotic disorders, short term management of nonpsychotic anxiety in patients with generalized anxiety disorder, and for the control of severe nausea and vomiting of various causes. | View | |
| PA1 | DB01296(Glucosamine) | Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question. | View | |
| PAC | DB09269(Phenylacetic acid) | For use as adjunctive therapy for the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle. | View | |
| PAR | DB01421(Paromomycin) | For the treatment of acute and chronic intestinal amebiasis (it is not effective in extraintestinal amebiasis). Also for the management of hepatic coma as adjunctive therapy. | View | |
| PAU | DB01783(Pantothenic acid) | Studied for the treatment of many uses such as treatment of testicular torsion, diabetic ulceration, wound healing, acne, obesity, diabetic peripheral polyneuropathy. It has also been investigated for its hypolipidemic effects and as cholesterol lowering agent. | View | |
| PCF | DB09114(Colfosceril palmitate) | Colfosceril palmitate is a drug used as a pulmonary surfactant. It is a drug that is used in surfactant deficient conditions such as IRDS in newborns. | View | |
| PE2 | DB00299(Penciclovir) | Used to treat recurrent cold sores on the lips and face from various herpesvirus invections. | View | |
| PEM | DB01393(Bezafibrate) | For the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus). | View | |
| PFL | DB00818(Propofol) | Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus. | View | |
| PFN | DB00573(Fenoprofen) | For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain. | View | |
| PM6 | DB01033(Mercaptopurine) | For remission induction and maintenance therapy of acute lymphatic leukemia. | View | |
| PNN | DB01053(Benzylpenicillin) | For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required such as in the treatment of septicemia, meningitis, pericarditis, endocarditis and severe pneumonia. | View | |
| PNT | DB00738(Pentamidine) | For the treatment of pneumonia due to <i>Pneumocystis carinii</i>. | View | |
| PNV | DB00417(Phenoxymethylpenicillin) | For the treatment of mild to moderately severe infections (e.g. dental infection, infections in the heart, middle ear infections, rheumatic fever, scarlet fever, skin infections, upper and lower respiratory tract infections) due to microorganisms. | View | |
| PNX | DB00806(Pentoxifylline) | For the treatment of patients with intermittent lameness or immobility arising from chronic occlusive arterial disease of the limbs. | View | |
| POD | DB01179(Podofilox) | For treatment of external genital warts (<i>Condyloma acuminatum</i>). | View | |
| PPF | DB00529(Foscarnet) | For the treatment of CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) and for treatment of acyclovir-resistant mucocutaneous HSV infections in immunocompromised patients. | View | |
| PQN | DB01022(Phylloquinone) | For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia. | View | |
| PRL | DB01123(Proflavine) | Topical antiseptic used mainly in wound dressings. | View | |
| PX9 | DB09345(Pramocaine) | It is indicated for temporary relief of pain and pruritus from minor lip and skin irritations as well as for temporary relief from pain, burning, itching and discomfort associated with hemorrhoids and other anorectal/anogenital disorders. | View | |
| PXB | DB08439(Parecoxib) | Used for short term perioperative pain control. | View | |
| PXL | DB00147(Pyridoxal) | Pyridoxal is one of the natural forms available of vitamin B6, therefore, it is used for nutritional supplementation and for treating dietary shortage or imbalances. | View | |
| PZA | DB00339(Pyrazinamide) | For the initial treatment of active tuberculosis in adults and children when combined with other antituberculous agents. | View | |
| PZE | DB00592(Piperazine) | Used as alternative treatment for ascariasis caused by <i>Ascaris lumbricoides</i> (roundworm) and enterobiasis (oxyuriasis) caused by <i>Enterobius vermicularis</i> (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children. | View | |
| PZI | DB09210(Piracetam) | For the treatment of myoclonus (brief, involuntary twitching of a muscle or a group of muscles). | View | |
| PZQ | DB01058(Praziquantel) | For the treatment of infections due to all species of schistosoma. | View | |
| QDN | DB00908(Quinidine) | For the treatment of ventricular pre-excitation and cardiac dysrhythmias | View | |
| QEL | DB08954(Ifenprodil) | View | ||
| QI9 | DB00468(Quinine) | For the treatment of malaria and leg cramps | View | |
| QMR | DB01273(Varenicline) | For use as an aid in smoking cessation. | View | |
| QPS | DB00284(Acarbose) | For treatment and management of diabetes type II (used in combination therapy as a second or third line agent) | View | |
| QUN | DB01103(Quinacrine) | For the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions. | View | |
| RAB | DB00194(Vidarabine) | For treatment of chickenpox - varicella, herpes zoster and herpes simplex | View | |
| RAL | DB00481(Raloxifene) | For the prevention and treatment of osteoporosis in post-menopausal women, as well as prevention and treatment of corticosteroid-induced bone loss. Also for the reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis or have a high risk for developing breast cancer. | View | |
| RAP | DB00877(Sirolimus) | For the prophylaxis of organ rejection in patients receiving renal transplants. | View | |
| RAU | DB01367(Rasagiline) | For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa. | View | |
| RAV | DB00312(Pentobarbital) | For the short-term treatment of insomnia. | View | |
| RBF | DB00140(Riboflavin) | For the treatment of ariboflavinosis (vitamin B2 deficiency). | View | |
| RBT | DB00615(Rifabutin) | For the prevention of disseminated <i>Mycobacterium avium</i> complex (MAC) disease in patients with advanced HIV infection. | View | |
| RBV | DB00811(Ribavirin) | Indicated for the treatment of chronic Hepatitis C virus (HCV) infection in combination with other antiviral agents with the intent to cure or achieve a sustained virologic response (SVR). Typically added to improve SVR and reduce relapse rates [A19644]. | View | |
| RCX | DB00533(Rofecoxib) | For the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. | View | |
| REA | DB00755(Tretinoin) | For the the induction of remission in patients with acute promyelocytic leukemia (APL), French-American-British (FAB) classification M3 (including the M3 variant); For the topical treatment of acne vulgaris, flat warts and other skin conditions (psoriasis, ichthyosis congenita, icthyosis vulgaris, lamellar icthyosis, keratosis palmaris et plantaris, epidermolytic hyperkeratosis, senile comedones, senile keratosis, keratosis follicularis (Darier's disease), and basal cell carcinomas.); For palliative therapy to improve fine wrinkling, mottled hyperpigmentation, roughness associated with photodamage. | View | |
| REM | DB00212(Remikiren) | For the treatment of hypertension and heart failure | View | |
| RFP | DB01045(Rifampicin) | For the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections. | View | |
| RFX | DB00472(Fluoxetine) | Labeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon. | View | |
| RGZ | DB00412(Rosiglitazone) | Rosiglitazone is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | View | |
| RIM | DB00478(Rimantadine) | For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults. | View | |
| RIO | DB03615(Ribostamycin) | A broad-spectrum antimicrobial isolated from <i>Streptomyces ribosifidicus</i>. Ribostamycin, along with other aminoglycosides with the DOS (2-deoxystreptamine) subunit, is an important broad-spectrum antibiotic with important use against human immunodeficiency virus and is considered a critically important antimicrobial by the World Health Organization. | View | |
| RIS | DB00884(Risedronate) | For the treatment of Paget's disease of the bone (osteitis deformans), postmenopausal and glucocorticoid-induced osteoporosis | View | |
| RIT | DB00503(Ritonavir) | Indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. | View | |
| RIV | DB06228(Rivaroxaban) | Rivaroxaban is indicated for the prevention of venous thromboembolic events (VTE) in patients who have undergone total hips replacements and total knee replacement surgery; prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE); to reduce risk of recurrent DVT and/or PE. Due to a lack of safety studies, it is not recommended for use in those under 18 years old. Its use is also not recommended in those with severe renal impairment (<30mL/min). | View | |
| RKE | DB01221(Ketamine) | Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior other general anesthetic agents and as a supplement of low potency agents.[L1336, FDA label] | View | |
| RLT | DB06817(Raltegravir) | For the treatment of HIV-1 infection in conjunction with other antiretrovirals. | View | |
| RO7 | DB08915(Aleglitazar) | Investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. | View | |
| ROC | DB01232(Saquinavir) | For the treatment of HIV-1 with advanced immunodeficiency together with antiretroviral nucleoside analogues. | View | |
| ROF | DB01656(Roflumilast) | Roflumilast is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations. Roflumilast is not a bronchodilator and is not indicated for the relief of acute bronchospasm. | View | |
| RPB | DB12332(Rucaparib) | Indicated as monotherapy for the treatment of patients with deleterious BRCA mutation (germline and/or somatic) associated advanced ovarian cancer who have been treated with two or more chemotherapies. Select patients for therapy based on an FDA-approved companion diagnostic for rucaparib. | View | |
| RPT | DB01201(Rifapentine) | For the treatment of pulmonary tuberculosis. | View | |
| RTL | DB00162(Vitamin A) | For the treatment of vitamin A deficiency. | View | |
| RTZ | DB00679(Thioridazine) | For the treatment of schizophrenia and generalized anxiety disorder. | View | |
| RWF | DB00682(Warfarin) | For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis. | View | |
| RXM | DB01220(Rifaximin) | Rifaximin has multiple indications by the FDA: for the treatment of patients (≥12 years of age) with traveller's diarrhea caused by noninvasive strains of Escherichia coli; for the reduction of overt hepatic encephalopathy recurrence in patients ≥18 years of age; and in May 2015 it was approved for irritable bowel syndrome with diarrhea (IBS-D) treatment in adult men and women. | View | |
| RXT | DB08877(Ruxolitinib) | Treatment of intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera (post-PV) myelofibrosis and post-essential thrombocythemia (post-ET) myelofibrosis. [Lexicomp] Myeolofibrosis is the proliferation of abnormal bone marrow stem cells which cause fibrosis (the excessive formation of connective tissue). | View | |
| RZX | DB01129(Rabeprazole) | For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use. | View | |
| SAL | DB00936(Salicylic acid) | Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts. | View | |
| SAM | DB00118(S-Adenosylmethionine) | S-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as a dietary supplement for the support of bone and joint health, as well as mood and emotional well being. | View | |
| SAN | DB00259(Sulfanilamide) | For the treatment of vulvovaginitis caused by <i>Candida albicans</i>. | View | |
| SAS | DB00795(Sulfasalazine) | For the treatment of Crohn's disease and rheumatoid arthritis as a second-line agent. | View | |
| SC2 | DB06151(Acetylcysteine) | Acetylcysteine is used mainly as a mucolytic and in the management of paracetamol (acetaminophen) overdose. | View | |
| SCK | DB00202(Succinylcholine) | Used in surgical procedures where a rapid onset and brief duration of muscle relaxation is needed (includes intubation, endoscopies, and ECT) | View | |
| SFX | DB00472(Fluoxetine) | Labeled indication include: major depressive disorder (MDD), moderate to severe bulimia nervosa, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic disorder with or without agoraphobia, and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism, mild dementia-associated agitation in nonpsychotic patients, post-traumatic stress disorder (PTSD), social anxiety disorder, chronic neuropathic pain, fibromyalgia, and Raynaud's phenomenon. | View | |
| SFY | DB00891(Sulfapyridine) | For the treatment of dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum | View | |
| SHH | DB02546(Vorinostat) | For the treatment of cutaneous manifestations in patients with cutaneous T-cell lymphoma who have progressive, persistent or recurrent disease on or following two systemic therapies. | View | |
| SMX | DB01326(Cefamandole) | For the treatment of serious infections caused by susceptible strains of microorganisms. | View | |
| SNL | DB00421(Spironolactone) | Used primarily to treat low-renin hypertension, hypokalemia, and Conn's syndrome. | View | |
| SNP | DB00571(Propranolol) | For the prophylaxis of migraine. | View | |
| SOR | DB01638(Sorbitol) | Used as a non-stimulant laxative via an oral suspension or enema. | View | |
| SPM | DB00127(Spermine) | For nutritional supplementation, also for treating dietary shortage or imbalance | View | |
| SPP | DB00705(Delavirdine) | For the treatment of HIV-1 infection in combination with appropriate antiretroviral agents when therapy is warranted | View | |
| SPR | DB06145(Spiramycin) | Macrolide antibiotic for treatment of various infections. | View | |
| SRE | DB01104(Sertraline) | For the management of major depressive disorder (MDD), posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), panic disorder (PD) with or without agoraphobia, premenstrual dysphoric disorder (PMDD), and social anxiety disorder (SAD) [FDA Label]. | View | |
| SRY | DB01082(Streptomycin) | For the treatment of tuberculosis. May also be used in combination with other drugs to treat tularemia (Francisella tularensis), plague (Yersia pestis), severe M. avium complex, brucellosis, and enterococcal endocarditis (e.g. E. faecalis, E. faecium). | View | |
| STI | DB00619(Imatinib) | For the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST). | View | |
| STR | DB00396(Progesterone) | For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer. | View | |
| STZ | DB00428(Streptozocin) | For the treatment of malignant neoplasms of pancreas (metastatic islet cell carcinoma). | View | |
| SUE | DB11575(Grazoprevir) | Grazoprevir is indicated in combination with [DB11574] (as the fixed dose combination product Zepatier) with or without [DB00811] for treatment of chronic HCV genotypes 1a, 1b, or 4 infection in adults. | View | |
| SUV | DB09034(Suvorexant) | Suvorexant is indicated for the treatment of insomnia characterized by difficulties with sleep onset and/or sleep maintenance. | View | |
| SUZ | DB00605(Sulindac) | For acute or long-term use in the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute painful shoulder (acute subacromial bursitis/supraspinatus tendinitis), and acute gouty arthritis. | View | |
| SVR | DB04786(Suramin) | For treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms. | View | |
| SWF | DB00682(Warfarin) | For the treatment of retinal vascular occlusion, pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, transient cerebral ischaemia, arterial embolism and thrombosis. | View | |
| T0R | DB00539(Toremifene) | For the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or receptor-unknown tumors. Toremifene is currently under investigation as a preventative agent for prostate cancer in men with high-grade prostatic intraepithelial neoplasia and no evidence of prostate cancer. | View | |
| T1C | DB00560(Tigecycline) | For the treatment of infections caused by susceptible strains of the designated microorganisms in the following conditions: Complicated skin and skin structure infections caused by <i>Escherichia coli</i>, <i>Enterococcus faecalis</i> (vancomycin-susceptible isolates only), <i>Staphylococcus aureus</i> (methicillin-susceptible and -resistant isolates), <i>Streptococcus agalactiae</i>, <i>Streptococcus anginosus</i> grp. (includes <i>S. anginosus</i>, <i>S. intermedius</i>, and <i>S. constellatus</i>), <i>Streptococcus pyogenes</i> and <i>Bacteroides fragilis</i>. Complicated intra-abdominal infections caused by <i>Citrobacter freundii</i>, <i>Enterobacter cloacae</i>, <i>Escherichia coli</i>, <i>Klebsiella oxytoca</i>, <i>Klebsiella pneumoniae</i>, <i>Enterococcus faecalis</i> (vancomycin-susceptible isolates only), <i>Staphylococcus aureus</i> (methicillin-susceptible isolates only), <i>Streptococcus anginosus</i> grp. (includes <i>S. anginosus</i>, <i>S. intermedius</i>, and <i>S. constellatus</i>), <i>Bacteroides fragilis</i>, <i>Bacteroides thetaiotaomicron</i>, <i>Bacteroides uniformis</i>, <i>Bacteroides vulgatus</i>, <i>Clostridium perfringens</i>, and <i>Peptostreptococcus micros</i>. | View | |
| T22 | DB06203(Alogliptin) | Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. | View | |
| T27 | DB08864(Rilpivirine) | Rilpivirine, in combination with other agents, is indicated for the treatment of HIV-1 infections in antiretroviral treatment-naive patients with HIV-1 RNA ≤100,000 copies/mL and CD4+ cell count >200 cells/mm3.[L1030] The FDA combination therapy approval of rilpivirine and dolutegravir is indicated for adults with HIV-1 infections whose virus is currently suppressed (< 50 copies/ml) on a stable regimen for at least six months, without history of treatment failure and no known substitutions associated to resistance to any of the two components of the therapy.[L1031] | View | |
| T44 | DB00451(Levothyroxine);DB00509(Dextrothyroxine) | For use alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.;Used to lower high cholesterol levels in the blood. | View | |
| T98 | DB04787(Tanaproget) | View | ||
| TA1 | DB01229(Paclitaxel) | Used in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast. Abraxane® is specfically indicated for the treatment of metastatic breast cancer and locally advanced or metastatic non-small cell lung cancer. | View | |
| TAC | DB00759(Tetracycline) | Used to treat bacterial infections such as Rocky Mountain spotted fever, typhus fever, tick fevers, Q fever, rickettsialpox and Brill-Zinsser disease. May be used to treat infections caused by Chlamydiae spp., B. burgdorferi (Lyme disease), and upper respiratory infections caused by typical (S. pneumoniae, H. influenzae, and M. catarrhalis) and atypical organisms (C. pneumoniae, M. pneumoniae, L. pneumophila). May also be used to treat acne. Tetracycline may be an alternative drug for people who are allergic to penicillin. | View | |
| TAZ | DB01606(Tazobactam) | Used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action. | View | |
| TC9 | DB01199(Tubocurarine) | Used as a diagnosis agent for myasthenia gravis, and also to facilitate the intubation after induction of anesthesia in surgical procedure | View | |
| TCI | DB00470(Dronabinol) | For the treatment of anorexia associated with weight loss in patients with AIDS, and nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments | View | |
| TCW | DB00323(Tolcapone) | Used as an adjunct to levodopa/carbidopa therapy for the symptomatic treatment of Parkinson's Disease. This drug is generally reserved for patients with parkinsonian syndrome receiving levodopa/carbidopa who are experiencing symptom fluctuations and are not responding adequately to or are not candidates for other adjunctive therapies. | View | |
| TDZ | DB00197(Troglitazone) | For the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise. | View | |
| TE4 | DB09085(Tetracaine) | The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures. | View | |
| TEI | DB04854(Febuxostat) | For the treatment of hyperuricemia in patients with gout. | View | |
| TEP | DB00277(Theophylline) | For the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, such as emphysema and chronic bronchitis. | View | |
| TES | DB00624(Testosterone) | To be used as hormone replacement or substitution of diminished or absent endogenous testosterone. Use in males: For management of congenital or acquired hypogonadism, hypogonadism associated with HIV infection, and male climacteric (andopause). Use in females: For palliative treatment of androgen-responsive, advanced, inoperable, metastatis (skeletal) carcinoma of the breast in women who are 1-5 years postmenopausal; testosterone esters may be used in combination with estrogens in the management of moderate to severe vasomotor symptoms associated with menopause in women who do not respond to adequately to estrogen therapy alone. | View | |
| TF4 | DB08809(Dichloroacetic Acid) | View | ||
| TFO | DB00300(Tenofovir) | View | ||
| TFP | DB00831(Trifluoperazine) | For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation. | View | |
| THA | DB00382(Tacrine) | For the palliative treatment of mild to moderate dementia of the Alzheimer's type. | View | |
| THH | DB11256(Levomefolic acid) | Treatment and prevention of folate deficiency Antidote against folic acid antagonists | View | |
| THR | DB00156(L-Threonine) | L-Threonine makes up collagen, elastin, and enamel protein. It aids proper fat metabolism in the liver, helps the digestive and intestinal tracts function more smoothly, and assists in metabolism and assimilation. | View | |
| TIC | DB00208(Ticlopidine) | Used in patients, who have had a stroke or stroke precursors and who cannot take aspirin or aspirin has not worked, to try to prevent another thrombotic stroke. | View | |
| TIM | DB00373(Timolol) | In its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma. | View | |
| TIQ | DB08816(Ticagrelor) | For the prevention of thrombotic events (for example stroke or heart attack) in patients with acute coronary syndrome or myocardial infarction with ST elevation. | View | |
| TKT | DB11699(Tropisetron) | For the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative. | View | |
| TLF | DB09216(Tolfenamic Acid) | For the treatment of migraine. | View | |
| TLS | DB00966(Telmisartan) | Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors). | View | |
| TLT | DB00500(Tolmetin) | For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis. | View | |
| TMG | DB00730(Thiabendazole) | For the treatment of strongyloidiasis (threadworm), cutaneous larva migrans (creeping eruption), visceral larva migrans, and trichinosis. | View | |
| TMI | DB04794(Bifonazole) | Used for the treatment of various topical fungal infections, including athlete's foot (tinea pedis). | View | |
| TMQ | DB01157(Trimetrexate) | For use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii</i> pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer. | View | |
| TNG | DB00727(Nitroglycerin) | For the prevention of angina | View | |
| TOP | DB00440(Trimethoprim) | For the treatment of urinary tract infections, uncomplicated pyelonephritis (with sulfamethoxazole) and mild acute prostatitis. May be used as pericoital (with sulfamethoxazole) or continuous prophylaxis in females with recurrent cystitis. May be used as an alternative to treat asymptomatic bacteriuria during pregnancy (only before the last 6 weeks of pregnancy). Other uses include: alternative agent in respiratory tract infections (otitis, sinusitus, bronchitis and pneumonia), treatment of Pneumocystis jirovecii pneumonia (acute or prophylaxis), Nocardia infections, and traveller's diarrhea. | View | |
| TOR | DB00273(Topiramate) | Used for the treatment and control of partial seizures and severe tonic-clonic (grand mal) seizures and also for the prevention of migraine headaches. In children it is also used for treatment of Lennox-Gastaut syndrome. Qsymia® is indicated for the treatment and management of obesity. | View | |
| TOY | DB00684(Tobramycin) | For the treatment of pseudomonas aeruginosa lung infections. Also being investigated for use in the treatment of sinus infections. | View | |
| TP0 | DB00321(Amitriptyline) | - Indicated for the treatment of major depressive disorder in adults | View | |
| TPA | DB00752(Tranylcypromine) | For the treatment of major depressive episode without melancholia. | View | |
| TPF | DB00196(Fluconazole) | For the treatment of fungal infections. | View | |
| TPV | DB00932(Tipranavir) | For combination antiretroviral treatment of HIV-1 infected adult patients with evidence of viral replication, who are highly treatment-experienced or have HIV-1 strains resistant to multiple protease inhibitors. | View | |
| TR6 | DB00685(Trovafloxacin) | For treatment of infections caused by susceptible strains of the designated microorganisms in uncomplicated urethral gonorrhea in males and endocervical and rectal gonorrhea in females caused by <i>Neisseria gonorrhoeae</i> as well as non gonoccocal urethritis and cervicitis due to <i>Chlamydia trachomatis</i>. | View | |
| TRP | DB00150(L-Tryptophan) | Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight. | View | |
| TRU | DB01021(Trichlormethiazide) | Used in the treatment of oedema (including that associated with heart failure) and hypertension. | View | |
| TTC | DB01030(Topotecan) | For the treatment of advanced ovarian cancer in patients with disease that has recurred or progressed following therapy with platinum-based regimens. Also used as a second-line therapy for treatment-sensitive small cell lung cancer, as well as in combination with cisplatin for the treatment of stage IV-B, recurrent, or persistent cervical cancer not amenable to curative treatment with surgery and/or radiation therapy. | View | |
| TUB | DB01199(Tubocurarine) | Used as a diagnosis agent for myasthenia gravis, and also to facilitate the intubation after induction of anesthesia in surgical procedure | View | |
| TXC | DB00577(Valaciclovir) | For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals. | View | |
| TXL | DB01248(Docetaxel) | For the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in the treatment of patients with locally advanced or metastatic non-small cell lung cancer after failure of prior platinum-based chemotherapy. It is also used in combination with prednisone, in the treatment of patients with androgen independent (hormone refractory) metastatic prostate cancer. Furthermore, docetaxel has uses in the treatment of gastric adenocarinoma and head and neck cancer. | View | |
| TYL | DB00316(Acetaminophen) | For temporary relief of fever, minor aches, and pains. | View | |
| TZN | DB01162(Terazosin) | For the treatment of symptomatic BPH and mild to moderate hypertension. | View | |
| UEG | DB00165(Pyridoxine) | Pyridoxine is indicated for the treatment of vitamin B6 deficiency and for the prophylaxis of [DB00951]-induced peripheral neuropathy. It is also approved by Health Canada for the treatment of nausea and vomiting in pregnancy in a combination product with [DB00366] (as the commercially available product Diclectin). | View | |
| URF | DB00544(Fluorouracil) | For the topical treatment of multiple actinic or solar keratoses. In the 5% strength it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. Fluorouracil injection is indicated in the palliative management of some types of cancer, including colon, esophageal, gastric, rectum, breast, biliary tract, stomach, head and neck, cervical, pancreas, renal cell, and carcinoid. | View | |
| V2H | DB06410(Doxercalciferol) | Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. | View | |
| VD3 | DB00169(Cholecalciferol) | For the treatment of vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or corticosteroid-induced osteoporosis. | View | |
| VDN | DB00862(Vardenafil) | Used for the treatment of erectile dysfunction | View | |
| VDX | DB00136(Calcitriol) | Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or corticosteroid-induced osteoporosis. | View | |
| VDY | DB00146(Calcidiol) | Used to treat vitamin D deficiency or insufficiency, refractory rickets (vitamin D resistant rickets), familial hypophosphatemia and hypoparathyroidism, and in the management of hypocalcemia and renal osteodystrophy in patients with chronic renal failure undergoing dialysis. Also used in conjunction with calcium in the management and prevention of primary or corticosteroid-induced osteoporosis. | View | |
| VGH | DB08865(Crizotinib) | Crizotinib is used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic-lymphoma kinase (ALK)-positive as detected by a FDA-approved test. | View | |
| VIA | DB00203(Sildenafil) | For the treatment of erectile dysfunction and to relieve symptoms of pulmonary arterial hypertension (PAH). | View | |
| VIB | DB00152(Thiamine) | For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis. | View | |
| VIS | DB08828(Vismodegib) | Vismodegib is used for treating locally advanced or metastatic basal cell carcinoma in patients whose carcinoma has recurred after surgery, and in patients who are not candidates for surgery or radiation. | View | |
| VIV | DB00163(Vitamin E) | Vitamin E, known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. It may be of limited benefit in some with asthma and rheumatoid arthritis. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. It may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. It may help relieve some muscle cramps. | View | |
| VK3 | DB00170(Menadione) | The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. | View | |
| VLB | DB00570(Vinblastine) | For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. | View | |
| VOG | DB04878(Voglibose) | For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications. | View | |
| VOR | DB00582(Voriconazole) | For the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by <i>Scedosporium apiospermum</i> and <i>Fusarium</i> spp. | View | |
| VPX | DB09030(Vorapaxar) | Vorapaxar is indicated for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or peripheral arterial disease (PAD). It is usually co-administered with acetylsalicylic acid (ASA) and/or clopidogrel, and should therefore be administered as an addition to these medications as it has not been studied alone. | View | |
| W9T | DB00581(Lactulose) | For the treatment of constipation and hepatic encephalopathy. | View | |
| WJZ | DB06823(Tiopronin) | Tiopronin is indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria consisting of a urinary cystine concentration greater than 500 mg/day, and who have failed treatment with non-pharmacological measures of increased fluid intake, decreased sodium and protein intake, and urine alkalinization. | View | |
| WPP | DB00319(Piperacillin) | For the treatment of polymicrobial infections. | View | |
| X0T | DB00651(Dyphylline) | For relief of acute bronchial asthma and for reversible bronchospasm associated with chronic bronchitis and emphysema. | View | |
| X2N | DB01263(Posaconazole) | For prophylaxis of invasive <em>Aspergillus</em> and <em>Candida</em> infections in patients, 13 years of age and older, who are at high risk of developing these infections due to being severely immunocompromised as a result of procedures such as hematopoietic stem cell transplant (HSCT) recipients with graft-versus-host disease (GVHD), or due to hematologic malignancies with prolonged neutropenia from chemotherapy. Also for the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole. Posaconazole is used as an alternative treatment for invasive aspergillosis, <em>Fusarium</em> infections, and zygomycosis in patients who are intolerant of, or whose disease is refractory to, other antifungals. | View | |
| X6X | DB01296(Glucosamine) | Glucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question. | View | |
| X89 | DB01110(Miconazole) | For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by <i>Trichophyton rubrum</i>, <i>Trichophyton mentagrophytes</i>, and <i>Epidermophyton floccosum</i>, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor. | View | |
| X8Z | DB01197(Captopril) | For the treatment of essential or renovascular hypertension (usually administered with other drugs, particularly thiazide diuretics). May be used to treat congestive heart failure in combination with other drugs (e.g. cardiac glycosides, diuretics, β-adrenergic blockers). May improve survival in patients with left ventricular dysfunction following myocardial infarction. May be used to treat nephropathy, including diabetic nephropathy. | View | |
| XIN | DB09079(Nintedanib) | Nintedanib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF). | View | |
| XPG | DB00770(Alprostadil) | For palliative, not definitive, therapy to temporarily maintain the patency of the ductus arteriosus until corrective or palliative surgery can be performed in neonates who have congenital heart defects and who depend upon the patent ductus for survival. Also for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology. | View | |
| XRA | DB00457(Prazosin) | For treatment of hypertension, symptomatic benign prostatic hyperplasia, and severe congestive heart failure. May also be used alone or in combination with β-blockers in the preoperative management of signs and symptoms of pheochromocytoma. | View | |
| Y00 | DB00841(Dobutamine) | For inotropic support in the short- term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures | View | |
| Y70 | DB08910(Pomalidomide) | Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy. | View | |
| YMZ | DB00358(Mefloquine) | For the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of <i>Plasmodium falciparum</i> (both chloroquine-susceptible and resistant strains) or by <i>Plasmodium vivax</i>. Also for the prophylaxis of <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> malaria infections, including prophylaxis of chloroquine-resistant strains of <i>Plasmodium falciparum</i>. | View | |
| YNU | DB00700(Eplerenone) | For improvement of survival of stable patients with left ventricular systolic dysfunction (ejection fraction <40%) and clinical evidence of congestive heart failure after an acute myocardial infarction. | View | |
| YTZ | DB06147(Sulfathiazole) | Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. | View | |
| YY3 | DB09330(Osimertinib) | Osimertinib is indicated for the treatment of patients with metastatic epidermal growth factor receptor (EGFR) T790M mutation-positive non-small cell lung cancer (NSCLC), as detected by an FDA- approved test, who have progressed on or after EGFR-TKI therapy. | View | |
| Z80 | DB00477(Chlorpromazine) | For the treatment of schizophrenia; to control nausea and vomiting; for relief of restlessness and apprehension before surgery; for acute intermittent porphyria; as an adjunct in the treatment of tetanus; to control the manifestations of the manic type of manic-depressive illness; for relief of intractable hiccups; for the treatment of severe behavioral problems in children (1 to 12 years of age) marked by combativeness and/or explosive hyperexcitable behavior (out of proportion to immediate provocations), and in the short-term treatment of hyperactive children who show excessive motor activity with accompanying conduct disorders consisting of some or all of the following symptoms: impulsivity, difficulty sustaining attention, aggressivity, mood lability, and poor frustration tolerance. | View | |
| ZD6 | DB05294(Vandetanib) | Vandetanib is currently approved as an alternative to local therapies for both unresectable and disseminated disease. Because Vandetanib can prolong the Q-T interval, it is contraindicated for use in patients with serious cardiac complications such as congenital long QT syndrome and uncompensated heart failure. | View | |
| ZIT | DB00207(Azithromycin) | For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions: <i>H. influenzae</i>, <i>M. catarrhalis</i>, <i>S. pneumoniae</i>, <i>C. pneumoniae</i>, <i>M. pneumoniae</i>, <i>S. pyogenes</i>, <i>S. aureus</i>, <i>S. agal</i> | View | |
| ZK5 | DB00687(Fludrocortisone) | For partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome. | View | |
| ZLD | DB00601(Linezolid) | For the treatment of bacterial infections caused by susceptible strains of vancomycin resistant <i>Enterococcus faecium</i>, <i>Staphylococcal aureus</i> (methicillin resistant and susceptible strains), <i>Streptococcus pneumoniae</i>, <i>Streptococcus pyogenes</i>, <i>Streptococcus agalactiae</i>. | View | |
| ZMR | DB00558(Zanamivir) | For the prevention and treatment of influenza A and B. | View | |
| ZOL | DB00399(Zoledronic acid) | For the treatment of hypercalcemia of malignancy. Also for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. In May of 2007, the drug was approved for treatment of Paget’s Disease. | View | |
| ZON | DB00909(Zonisamide) | For use as adjunctive treatment of partial seizures in adults with epilepsy. | View | |
| ZOT | DB09225(Zotepine) | For the treatment of acute and chronic schizophrenia. | View | |
| ZPC | DB00402(Eszopiclone);DB01198(Zopiclone) | For the treatment of insomnia;For the short-term treatment of insomnia. | View | |
| T3 | DB00279(Liothyronine) | Used as replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis. | View |