Ligand ID: P1Z


Drugbank ID:
DB00812
(Phenylbutazone)


Indication:
For the treatment of backache and ankylosing spondylitis

Get human targets for P1Z in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'P1Z'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.52A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.12A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 6
THR A 190
MET A 165
LYS A 180
PHE A 181
1.77A24.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		6 / 12
PHE B  90
LEU B  45
LEU B   9
ALA A 108
SER A 105
ALA B 107
1.42A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		1ssk NUCLEOCAPSID PROTEIN
(SARSr)		4 / 7
TYR A  65
LEU A 137
ASN A  53
TYR A  87
1.31A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.10A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		1uw7 NSP9
(SARS-COV
HKU-39849)		6 / 12
LEU A  51
HIS A  48
LEU A  44
ALA A  30
SER A  13
ALA A  15
1.54A11.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
ILE A 213
PHE A   3
MET A   6
LEU B 141
LEU A  -2
1.51A23.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 213
PHE A   3
LEU B 141
LEU A  -2
0.91A23.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.10A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		1xak ORF7A ACCESSORY
PROTEIN
(SARSr-CoV)		5 / 10
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.65A12.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		1xak ORF7A ACCESSORY
PROTEIN
(SARSr-CoV)		5 / 8
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.71A12.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.72A23.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.51A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.14A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU K  44
LEU I  48
ILE H   2
ILE H   5
ALA G  40
1.46A6.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE D   5
LEU A  44
VAL A  45
LEU A  41
1.09A6.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 6
THR B 190
MET B 165
LYS B 180
PHE B 181
1.77A24.59
None
AZP  B 307 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.15A18.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 10
ILE C 335
PHE C 298
TYR C 191
LEU C 305
VAL C 216
1.73A17.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 12
LEU C  64
LEU G  96
LEU G 100
ILE G 112
ILE C  73
1.48A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 8
ILE H 112
LEU D  18
VAL D  21
LEU D  64
1.07A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		2ajf ACE2
(Homo
sapiens)		4 / 6
ASP B  38
TYR B  41
PHE B  32
LEU B 391
1.39A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2ajf ACE2
(Homo
sapiens)		5 / 10
TYR A 207
TYR A 516
ILE A 513
TYR A 217
LEU A 520
1.73A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.56A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.16A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LYS D1148
LEU C 944
LEU A 944
LEU B 941
ILE E1154
1.32A6.29
ACE  D1147 ( 2.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE E1151
LEU A 948
VAL A 945
LEU A 944
0.96A7.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE C 916
LEU B 920
VAL D1171
LEU D1175
1.11A8.50
ACE  C 913 ( 4.1A)
None
None
ACE  B 913 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2bx3 MAIN PROTEINASE
(SARS-COV
Sin2774)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.46A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.50A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		5 / 9
GLU H  46
LEU H  82
ARG H  83
LEU H  82
ALA H  88
1.71A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
TYR A  72
LEU A 151
ASN A 147
ASP A 144
1.68A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
PHE C 128
LEU C 118
VAL C 117
LEU C 121
1.14A20.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 12
LEU M  14
PHE R  19
LEU M  75
ILE M  81
ALA M  20
1.29A13.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR C 352
PHE C 325
LEU C 421
VAL C 497
LEU C 499
1.70A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
TYR C 352
PHE C 325
LEU C 421
VAL C 497
LEU C 499
1.65A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.51A18.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 6
GLU A 201
MET A 251
LYS A 204
PHE A 203
1.78A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2liz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.51A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.13A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.51A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
GLU C 201
MET C 251
LYS C 204
PHE C 203
1.39A22.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
LEU A 299
PHE A 302
LEU A 227
ILE A 306
ILE A 235
1.26A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.58A19.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.71A23.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.54A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.13A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.13A18.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.13A18.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
GLU C 201
MET C 251
LYS C 204
PHE C 203
1.65A22.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.14A18.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		2wct NSP3
(SARSr-CoV)		4 / 6
THR D 612
GLU B 403
MET D 606
ILE D 549
1.30A22.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr)		4 / 7
ASN A 143
LYS A 139
TYR A 132
LYS A 146
1.49A20.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 9
GLU A 217
LEU A 180
LEU A 183
HIS A 186
ALA A 209
1.67A18.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
TYR A 181
ILE A 219
LEU A 206
VAL A 169
LEU A 180
1.68A20.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
TYR A 181
ILE A 219
LEU A 206
VAL A 169
LEU A 180
1.68A20.71
None
CL  A1296 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
PHE A 187
LEU A 126
ILE A 157
SER A 129
ALA A 168
1.48A17.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 9
GLU A 217
LEU A 180
LEU A 183
HIS A 186
ALA A 209
1.64A17.32
None
None
None
None
CL  A1299 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.71A24.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.11A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		5 / 10
TYR S 338
ILE S 455
TYR A 484
TYR A 436
LEU S 478
1.50A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
GLU C 123
VAL B 121
GLY B 141
GLU B 213
ILE B 212
1.77A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
TYR F 408
TYR B  34
LEU F 443
TYR F 440
1.14A20.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ASP B 509
TYR B 510
TYR B 180
LEU B 456
1.47A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
TYR E 408
TYR A  34
LEU E 443
TYR E 440
1.11A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
TYR F 408
TYR B  34
LEU F 443
TYR F 440
1.08A20.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.71A24.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.50A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.71A23.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		3e9s NSP3
(SARSr-CoV)		4 / 8
PHE A 128
LEU A 118
VAL A 117
LEU A 121
1.11A19.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.13A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.52A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR B 209
ILE B 259
PHE B 219
VAL B 204
LEU B 208
1.72A23.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.16A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		6 / 12
LEU D 208
PHE D 219
LEU D 205
ALA B 260
ILE B 259
ALA B 266
1.50A12.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
LEU D 208
LEU D 205
ALA B 260
ILE B 259
ALA B 266
1.13A12.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		6 / 12
LEU D  51
HIS D  48
LEU D  44
ALA D  30
SER D  13
ALA D  15
1.56A11.60
None
GOL  D 127 (-3.8A)
None
None
GOL  D 126 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.15A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.54A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.53A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
THR A 111
GLU A 290
LYS B   5
ILE A 136
1.77A24.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
GLU B 166
LYS A   2
PHE A   3
ILE B 136
1.58A24.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 230
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.54A18.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.14A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.52A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.59A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.14A19.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.55A19.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 8
PHE A 128
TYR A  84
LEU A 118
VAL A 117
LEU A 121
1.78A20.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
TYR A 181
ILE A 219
LEU A 206
VAL A 169
LEU A 180
1.64A20.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		4 / 6
LEU B  14
ASN B  10
LYS A  76
ASP A  75
1.79A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
LYS B 353
TYR F 436
ASN F 479
ASP F 393
1.54A19.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 7
TYR F 484
LEU B  39
LYS B  68
TYR F 436
1.60A22.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
TYR E 408
TYR A  34
LEU E 443
TYR E 440
1.06A20.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
TYR B 207
TYR B 516
ILE B 513
TYR B 217
LEU B 520
1.71A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ASP B 509
TYR B 510
TYR B 180
LEU B 456
1.50A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
TYR E 408
TYR A  34
LEU E 443
TYR E 440
1.10A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 230
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.50A18.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		3vb3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.68A24.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.13A18.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 8
PHE A 128
TYR A  84
LEU A 118
VAL A 117
LEU A 121
1.80A21.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.59A19.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		4 / 7
TYR B 306
LEU B 217
ASN B 216
TYR B 311
1.74A20.57
DMS  B 907 (-4.6A)
None
None
NA  B 903 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		6 / 10
PHE A 128
MET A 170
TYR A  84
LEU A 118
VAL A 117
LEU A 121
1.75A20.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		7 / 12
TRP A 243
LEU A 120
PHE A 148
LEU A 170
HIS A 171
LEU A 169
ILE A 152
1.78A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 8
ILE A  40
LEU A  20
VAL A  18
LEU A  30
1.10A23.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 10
TYR A  26
ILE A  40
LEU A  20
VAL A  18
LEU A  30
1.22A23.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.32A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
PHE B 219
LEU B 205
ILE B 259
ALA B 266
1.41A18.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.16A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
LEU B 208
PHE B 219
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.54A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 6
THR A   5
GLU A   6
MET B  57
PHE B  60
1.62A16.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 9
GLU B 284
LEU B 185
ARG B  76
ALA B  79
ALA B 281
1.72A21.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
TYR D 306
LEU D 217
ASN D 216
TYR D 311
1.63A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
LEU D 133
HIS D 176
LEU D 173
SER D 156
ALA D 154
1.41A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
ASP A 303
TYR A 274
TYR A 297
PHE A 259
1.56A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		6 / 10
PHE D 128
MET D 170
TYR D  84
LEU D 118
VAL D 117
LEU D 121
1.79A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5f22 NSP8
NSP7
(SARSr-CoV)		4 / 8
ILE B 112
LEU A  18
VAL A  21
LEU A  64
1.06A17.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		5f22 NSP7
(SARSr-CoV)		4 / 6
THR A  51
GLU A  52
MET A   8
ILE A  44
1.62A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 6
THR P   5
GLU P   6
MET C  57
PHE C  60
1.60A16.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		5r7y 3C-LIKE PROTEINASE
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.51A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		5r7z 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.12A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5r82 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.67A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A 239
LEU A 242
VAL A 202
LEU A 205
1.60A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 230
LEU A 250
VAL A 202
LEU A 205
1.72A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.54A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.12A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PHE A 230
LEU A 208
VAL A 204
LEU A 268
1.70A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.72A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.23A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 259
LEU A 205
VAL A 202
LEU A 250
1.75A18.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.60A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
TYR D  72
LEU D 151
ASN D 147
ASP D 144
1.78A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
PHE B 128
LEU B 118
VAL B 117
LEU B 121
1.14A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
TYR B  36
LEU B  88
ASN B  89
LYS B  92
1.31A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl6 UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens)		4 / 6
TYR A 140
LEU A 137
LYS A 108
ASP A 119
1.61A10.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
ASP D 144
TYR D 138
PHE D 148
LEU D 133
1.49A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
PHE B 128
MET B 170
LEU B 118
VAL B 117
LEU B 121
1.47A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5x4r S PROTEIN
(MERS-CoV)		5 / 10
TYR A 243
PHE A 254
LEU A 284
VAL A 263
LEU A 265
1.69A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ILE A 219
PHE A 187
TYR A 163
LEU A 222
LEU A 194
1.62A21.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP A  85
TYR A 197
PHE A 103
LEU A 194
1.46A21.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
THR A  92
GLU A  93
LYS A 175
ILE A  72
1.50A21.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ILE A 219
PHE A 187
TYR A 163
LEU A 222
LEU A 194
1.59A21.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 8
ILE C 219
PHE C 187
TYR C 163
LEU C 222
LEU C 194
1.77A14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		5x59 S PROTEIN
(MERS-CoV)		4 / 6
ASP C  54
TYR C  58
PHE C  75
LEU C 325
1.33A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 10
ILE B  87
PHE B 103
TYR B  88
VAL B 196
LEU B 194
1.62A14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
THR A 616
VAL A 307
GLY B 726
MET B 722
PHE A 578
1.78A14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
GLU B 755
LEU C 994
ARG B1001
ALA B1002
ALA B 997
1.70A17.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 7
TYR A 356
LEU A 374
ASN A 375
LYS A 566
1.65A14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		5x5c S PROTEIN
(MERS-CoV)		5 / 9
THR C 948
VAL C1127
GLY C 953
PHE C 865
ILE C 955
1.64A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
LEU A 415
PHE A 423
LEU A 414
ILE A 433
ILE A 573
1.34A18.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5x5f S PROTEIN
(MERS-CoV)		5 / 10
ILE B 573
PHE B 385
TYR B 438
LEU B 415
LEU B 414
1.66A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR C  42
ILE C 272
TYR C  53
LEU C  58
1.07A14.48
TYR  C  42 ( 1.3A)
ILE  C 272 ( 0.7A)
TYR  C  53 ( 1.3A)
LEU  C  58 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR B 723
ILE B 724
LEU B 959
VAL B 958
LEU B 978
1.66A14.48
TYR  B 723 ( 1.3A)
ILE  B 724 ( 0.6A)
LEU  B 959 ( 0.6A)
VAL  B 958 ( 0.6A)
LEU  B 978 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
PHE B 253
GLU B 184
GLY B 255
PHE B  89
ILE B  87
1.79A14.48
PHE  B 253 ( 1.3A)
GLU  B 184 ( 0.5A)
GLY  B 255 ( 0.0A)
PHE  B  89 ( 1.3A)
ILE  B  87 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
PHE A 128
MET A 170
LEU A 118
VAL A 117
LEU A 121
1.38A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 7
TYR A 306
LEU A 217
ASN A 216
TYR A 311
1.78A20.81
GOL  A 408 (-4.9A)
None
None
NA  A 403 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
THR B 236
PHE B 137
VAL B  97
GLY B 246
PHE B  76
1.53A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
TYR C 723
ILE C 724
LEU C 959
VAL C 958
LEU C 978
1.56A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
THR C 509
GLU C 502
PHE C 501
ILE C 345
1.69A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6acj ACE2
(Homo
sapiens)		4 / 6
ASP D  38
TYR D  41
PHE D  32
LEU D 391
1.16A19.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
LEU C 846
LEU A 597
ILE A 299
ILE A 650
ALA A 658
1.36A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASP B  85
TYR B 195
PHE B 103
LEU B 224
1.32A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ILE C  87
PHE C 103
TYR C  88
VAL C 196
LEU C 194
1.43A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 8
TYR C 723
ILE C 724
LEU C 959
VAL C 958
LEU C 978
1.65A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASP B  85
TYR B 197
PHE B 103
LEU B 194
1.28A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
LEU B 222
ILE B 228
SER B 113
ILE B 226
ALA B 127
1.47A17.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
THR C 921
GLU C 918
LYS C 911
ILE C 916
1.74A13.83
None
None
NAG  C1313 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
TYR B 819
LEU B 941
ASN B 942
ASP A 557
1.48A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
THR C  92
GLU C  93
LYS C 175
ILE C  72
1.33A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 8
TYR C 723
ILE C 724
LEU C 959
VAL C 958
LEU C 978
1.61A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
LEU A 222
ILE A 228
SER A 113
ILE A 226
ALA A 127
1.31A17.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASP C  85
TYR C 195
PHE C 187
LEU C 194
1.21A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
GLU A 184
VAL A 186
GLY A 255
PHE A 253
ILE A  87
1.80A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ILE C  87
PHE C 103
TYR C  88
VAL C 196
LEU C 194
1.38A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
TYR C 352
LEU C 421
ASN C 330
TYR C 356
1.75A13.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6cs2 ACE2
(Homo
sapiens)		4 / 6
ASP D  38
TYR D  41
PHE D  32
LEU D 391
1.45A20.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6jyt HELICASE
(SARSr-CoV)		5 / 12
LEU A 317
PHE A 357
HIS A 290
LEU A 295
ILE A 304
1.28A21.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6jyt HELICASE
(SARSr-CoV)		5 / 8
PHE B 200
TYR B 217
LEU B 219
VAL B 154
LEU B 163
1.71A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		6 / 12
SER D 968
GLN D 965
LEU E 959
LEU F 959
ILE E1172
ILE E1169
1.54A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
LEU F 948
LEU D 945
ILE D1179
SER E 940
ALA E 942
1.48A11.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 8
ILE D1169
LEU F 966
VAL F 963
LEU F 962
0.99A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.18A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.11A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.16A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.62A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.77A24.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE B 400
ARG B 408
ILE B 402
ILE B 418
ALA B 419
1.27A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.15A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.09A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.77A24.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.18A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 8
PHE C 403
TYR C 316
TYR C 231
LEU C 427
LEU C 424
1.67A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
PHE C 514
ARG C  97
LEU C  96
ILE C  92
SER C 291
1.44A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		6m17 ACE2
(Homo
sapiens)		5 / 9
TYR D 633
GLU D 639
LEU D 717
ARG B 710
ALA B 714
1.48A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 9
GLU D 312
VAL D 316
MET D 376
PHE D 308
GLU D 310
1.76A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6m1d ACE2
(Homo
sapiens)		4 / 6
GLU D 312
MET D 376
PHE D 327
ILE D 307
1.77A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
GLU C 501
MET C 542
PHE C 499
ILE C 496
1.44A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6m1d ACE2
(Homo
sapiens)		4 / 6
ASP B 509
TYR B 510
TYR B 127
TYR B 180
1.50A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		6m1d ACE2
(Homo
sapiens)		4 / 7
TYR B 633
LEU B 717
ASN B 712
TYR D 649
1.32A18.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.53A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.59A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
TYR C 209
ILE C 259
PHE C 219
VAL C 204
LEU C 208
1.75A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
GLN A 256
LEU A 220
ILE A 281
ALA A 211
1.71A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 208
PHE B 219
LEU B 205
ILE B 259
ALA B 266
1.60A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU D 208
LEU D 205
ALA D 260
ILE D 259
ALA D 266
1.11A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN D 244
LEU D 205
LEU D 250
ALA D 255
ALA D 260
1.73A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE C 230
PHE C 219
LEU C 287
ILE C 281
ALA C 206
1.46A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
LEU A 205
LEU A 250
ALA A 255
ALA A 260
1.79A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE D 230
PHE D 219
LEU D 287
ILE D 281
ALA D 206
1.46A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.07A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU D 208
LEU D 205
ALA D 260
ILE D 259
ALA D 266
1.18A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
TYR B 209
ILE B 259
PHE B 219
VAL B 204
LEU B 208
1.79A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN B 244
LEU B 205
LEU B 250
ALA B 255
ALA B 260
1.76A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 208
LEU B 205
ALA B 260
ILE B 259
ALA B 266
1.11A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE C 230
LEU C 268
LEU C 287
ILE C 281
ALA C 206
1.16A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE B 219
LEU B 268
LEU B 287
ILE B 281
ALA B 206
1.63A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 271
LEU A 272
ALA A 234
ALA A 266
1.41A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU B 208
LEU B 271
LEU B 272
ALA B 234
ALA B 266
1.41A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		6 / 12
PHE B 230
PHE B 219
LEU B 268
LEU B 287
ILE B 281
ALA B 206
1.50A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C 208
LEU C 205
ALA C 260
ILE C 259
ALA C 266
1.23A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
TYR D 209
ILE D 259
PHE D 219
VAL D 204
LEU D 208
1.73A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU D 208
PHE D 219
LEU D 205
ILE D 259
ALA D 266
1.65A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.63A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.77A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C 208
LEU C 205
ALA C 260
ILE C 259
ALA C 266
1.14A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		6 / 12
PHE A 230
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.50A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU C 208
LEU C 271
LEU C 272
ALA C 234
ALA C 266
1.49A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE D 230
LEU D 268
LEU D 287
ILE D 281
ALA D 206
1.18A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.12A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.15A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.74A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.08A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.20A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.62A17.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 888
PHE A 419
VAL A 880
LEU A 883
1.22A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.74A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
TYR A 237
SER A 236
LEU A 131
ILE A 145
ALA A 125
1.72A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  91
LEU C  59
ALA D 110
ILE C  68
ILE D 107
1.59A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
LEU A 575
ILE A 579
ILE A 589
ALA A 688
1.51A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 10
TYR A 732
PHE A 471
TYR A 788
LEU A 708
LEU A 727
1.79A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU D  91
VAL C  16
LEU C  13
1.40A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 453
ILE A 450
LEU A 388
VAL A 398
1.41A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ALA A 580
ILE A 579
ALA A 688
1.30A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  95
LEU C  56
LEU C  59
ILE C  68
ALA D 110
1.54A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ILE A 579
ILE A 589
ALA A 688
1.50A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		6 / 12
PHE A 157
TRP A 162
LEU A 142
LEU A 146
LEU A 178
ILE A 244
1.77A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 157
LEU A 131
LEU A 142
1.34A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 10
TYR A 453
ILE A 450
MET A 666
LEU A 388
VAL A 398
1.65A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
ILE A 579
ILE A 589
ALA A 688
1.58A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
PHE A 745
TYR A 732
LEU A 708
LEU A 707
1.39A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A 479
ILE A 696
TYR A 483
VAL A 605
1.41A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
PHE A 480
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.63A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 575
PHE A 480
LEU A 576
SER A 759
ALA A 690
1.45A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ASP A 218
TYR A 217
TYR A  87
LEU A  90
1.01A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.36A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
TYR A 723
ILE A 724
LEU A 959
VAL A 958
LEU A 978
1.63A14.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR A 723
ILE A 724
LEU A 959
VAL A 958
LEU A 978
1.66A14.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		4 / 8
TYR L 178
TYR L 145
LEU L  15
VAL L  83
0.96A23.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		6nur NSP12
(SARSr)		4 / 7
TYR A 237
LEU A 207
ASN A 209
TYR A 732
1.47A17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6nur NSP7
(SARSr-CoV)		4 / 6
GLU C  47
MET C   3
LYS C  43
ILE C  39
1.74A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6nur NSP12
(SARSr-CoV)		4 / 6
GLU A 370
MET A 380
PHE A 340
ILE A 333
1.68A17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6nur NSP12
NSP7
NSP8
(SARSr-CoV)		5 / 8
ILE C  39
PHE C  49
TYR A 420
LEU D  95
LEU D 103
1.71A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6nus NSP12
(SARSr-CoV)		4 / 6
ASP A 623
TYR A 456
TYR A 619
LEU A 630
1.44A17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6nus NSP12
(SARSr-CoV)		5 / 12
LEU A 638
LEU A 575
ILE A 579
ILE A 589
ALA A 688
1.41A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6nus NSP12
(SARSr-CoV)		6 / 12
SER A 682
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.49A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
LEU B 226
PHE B 175
LEU B 229
ILE B 128
ILE B 119
1.41A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxs NSP3
(SARS-CoV-2)		4 / 6
THR A 149
GLU A 120
LYS A   3
PHE A   6
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxs NSP3
(SARS-CoV-2)		4 / 8
ILE A 137
LEU A  12
VAL A  16
LEU A 153
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxs NSP3
(SARS-CoV-2)		4 / 8
ILE B 137
LEU B  12
VAL B  16
LEU B 153
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxs NSP3
(SARS-CoV-2)		4 / 8
ILE B 137
TYR B 161
LEU B 153
VAL B  16
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 365
PHE A 392
TYR A 369
VAL A 382
LEU A 390
1.53A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
TYR A 365
PHE A 392
TYR A 369
VAL A 382
LEU A 390
1.68A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LYS C 854
TYR C1007
ASN C 960
ASP B 568
1.73A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
ILE A 434
PHE A 429
TYR A 369
LEU A 387
VAL A 382
1.69A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B  29
PHE B  65
GLY B 268
PHE B  92
GLU B 191
1.68A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 10
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.69A13.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w37 PROTEIN 7A
(SARS-CoV-2)		5 / 8
TYR A  60
PHE A  39
TYR A   5
VAL A  14
LEU A  41
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 347
TRP C 436
PHE C 338
ILE C 358
SER C 514
1.64A12.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
PHE C 342
TYR C 423
VAL C 395
LEU C 513
1.66A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 400
LEU C 425
ALA C 411
ILE C 410
ALA C 419
1.44A12.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
TYR L  92
ILE L   2
TYR L  91
TYR L  96
1.55A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ILE L   2
TYR L  91
TYR L  32
LEU L  27
1.62A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ILE L   2
PHE L  71
TYR L  96
LEU L  27
1.49A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE C 342
TYR H  52
VAL C 512
LEU C 513
1.75A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
TYR L  86
GLN L  37
LEU L  15
LEU L  78
ALA L  12
1.72A13.33
None
SO4  L 302 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 8
ILE H  51
PHE H  29
TYR L  96
VAL H 102
LEU H   4
1.72A19.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
TYR L 173
TYR L 140
VAL L  13
LEU L  78
1.59A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR L  49
TYR L  91
TYR L  32
LEU C 390
1.64A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 358
PHE C 342
VAL C 367
LEU C 368
1.71A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR C 380
ILE H  98
TYR L  27
TYR L  32
1.63A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 374
LEU C 513
PHE C 515
LEU C 368
ALA C 363
1.76A12.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A6950
VAL A6865
LEU A6924
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6926
LEU A6857
VAL A6859
LEU A7050
1.62A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6845
ILE A6926
PHE A7003
LEU A6852
1.63A19.05
SAM  A7104 (-4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 NSP10
(SARS-CoV-2)		4 / 8
TYR B4283
LEU B4365
VAL B4361
LEU B4328
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.76A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A7026
ILE A7027
TYR A6813
LEU A6825
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
TYR A7009
LEU A6981
LEU A6978
1.60A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TRP A6886
LEU A6857
LEU A6924
LEU A6959
ALA A6966
1.52A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6845
LEU A6887
VAL A6865
LEU A6893
1.43A
SAM  A7104 (-4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7005
TYR A6845
LEU A6924
LEU A6857
1.63A19.05
None
SAM  A7104 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TRP A6886
LEU A6924
LEU A6959
ALA A6960
ALA A6858
1.76A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.74A12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6951
PHE A6868
LEU A6959
1.73A19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
ASN A6941
LYS A6936
TYR A6930
LYS A6944
1.51A19.05
None
KCX  A6935 ( 3.5A)
KCX  A6935 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
TYR A6950
VAL A6865
LEU A6924
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
PHE A6985
TYR A6950
LEU A6981
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TYR A6845
HIS A6867
ILE A6951
ILE A6967
ALA A6966
1.32A
SAM  A7104 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.74A23.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 271
LEU A 272
ALA A 234
ALA A 266
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE B 116
TYR B   9
VAL B  34
LEU B  93
1.73A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR A 113
LEU A  93
VAL A  36
LEU A 122
1.76A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR B 113
LEU B  93
VAL B  36
LEU B 122
1.75A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 126
LEU A 140
ILE A 137
ALA A 134
1.60A
None
AMP  A 201 ( 4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE A 168
TYR B 152
TYR B  17
VAL A  16
1.50A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE A 168
TYR A 152
LEU A 153
LEU A 140
1.75A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.66A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE A 168
TYR A   9
LEU A 153
LEU A 140
1.77A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 10
TYR B 161
TYR B   9
ILE B  18
VAL A 165
LEU A  10
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR A  42
ILE A  69
VAL A  96
LEU A  75
1.48A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR B   9
LEU A  12
VAL A 165
LEU A  10
1.73A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR B  42
ILE B  69
LEU B  75
VAL B  77
1.58A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR A 161
ILE A  18
VAL B 165
LEU B  10
1.74A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.55A13.76
None
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR B  42
ILE B  69
VAL B  96
LEU B  75
1.46A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR A  42
ILE A  69
LEU A  75
VAL A  77
1.64A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE B 116
TYR B   9
LEU B 126
LEU B 127
1.52A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.67A13.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
ARG A 141
LEU A 140
LEU A 126
ALA A 129
1.76A13.76
None
None
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.70A13.76
None
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PHE B 168
TYR B 152
LEU B 153
LEU B 140
1.78A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 126
LEU A 140
ILE A 137
ALA A 134
1.60A13.76
None
AMP  A 201 ( 4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR B 161
ILE B  18
VAL A 165
LEU A  10
1.45A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w6y NSP3
(SARS-CoV-2)		4 / 8
TYR A 152
TYR A  17
VAL B  16
LEU B  12
1.71A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
TYR C6950
VAL C6865
LEU C6924
1.27A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 8
PHE D4272
LEU B4365
VAL B4361
LEU B4328
1.24A16.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 8
PHE B4272
LEU D4365
VAL D4361
LEU D4328
1.20A16.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 8
TYR B4283
LEU B4365
VAL B4361
LEU B4328
1.37A16.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C6950
ILE C6951
PHE C6868
LEU C6959
1.71A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A7026
ILE A7027
TYR A6813
LEU A6825
1.27A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7005
TYR A6845
LEU A6924
LEU A6857
1.64A18.44
None
SAM  A7102 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
ILE C6955
SER C6927
ALA C6966
1.59A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TYR A6845
HIS A6867
ILE A6951
ILE A6967
ALA A6966
1.30A13.08
SAM  A7102 ( 4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TRP A6886
LEU A6924
LEU A6959
ALA A6960
ALA A6858
1.77A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 8
TYR D4283
LEU D4365
VAL D4361
LEU D4328
1.30A16.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7005
TYR C6845
LEU C6924
LEU C6857
1.62A18.44
None
SAM  C7105 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
SER C6927
ILE C6967
ALA C6966
1.49A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TRP A6886
LEU A6857
LEU A6924
LEU A6959
ALA A6966
1.53A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6926
LEU A6857
VAL A6859
LEU A7050
1.59A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.70A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TRP C6886
LEU C6924
LEU C6959
ALA C6960
ALA C6858
1.78A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6955
TYR A6950
VAL A6865
LEU A6924
1.29A18.44
None
FMT  A7109 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
THR A7032
MET A6818
LYS A6814
ILE A7027
1.75A18.44
None
None
FMT  A7111 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
LYS D4346
PHE C6868
LEU C6893
LEU C6892
ILE C7088
1.76A12.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.67A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6967
PHE C6985
TYR C6950
LEU C6981
1.43A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
ILE C6955
SER C6927
ALA C6966
1.57A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.47A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A6887
LEU A7050
LEU A6852
ILE A6926
SER A6964
1.49A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.49A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.50A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6926
LEU C6857
VAL C6859
LEU C7050
1.59A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6967
TYR C7026
LEU C6848
LEU C6852
1.51A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6925
TYR A7009
LEU A6981
LEU A6978
1.62A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.47A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.58A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TRP C6886
LEU C6857
LEU C6924
LEU C6959
ALA C6966
1.54A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6951
PHE A6868
LEU A6959
1.76A18.44
FMT  A7109 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A7026
LEU A6848
LEU A6852
1.53A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C7026
ILE C7027
TYR C6813
LEU C6825
1.44A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6925
TYR C7009
LEU C6981
LEU C6978
1.62A18.44
None
NA  C7103 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
PHE A6985
TYR A6950
LEU A6981
1.40A18.44
None
None
FMT  A7109 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6967
TYR C6950
VAL C6865
LEU C6924
1.31A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.55A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C7073
LEU C7078
LEU C7060
ILE C7065
ALA C6960
1.64A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A6950
VAL A6865
LEU A6924
1.30A18.44
None
FMT  A7109 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C6959
PHE C6985
SER C6927
ILE C6967
ALA C6966
1.78A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
LEU C7073
LEU C7078
LEU C7060
ILE C7065
ALA C6960
1.67A13.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
TYR C6845
HIS C6867
ILE C6951
ILE C6967
ALA C6966
1.31A13.08
SAM  C7105 ( 4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ILE C 123
TYR C 213
LEU C 178
VAL C 202
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ILE A 123
PHE A 173
TYR A 213
LEU A 178
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU B 117
LEU B 120
LEU B 172
ILE B 151
ALA B 135
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASP C 164
TYR C 171
TYR C 112
LEU C 172
1.59A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
ASP A 164
TYR A 171
TYR A 112
LEU A 172
1.68A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
TYR C  95
LEU C 113
ASN C 110
ASP C 286
1.77A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 262
LEU A 152
ALA A 144
ILE A 104
ALA A 114
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
PHE C 216
LEU C 199
VAL C 184
LEU C 185
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
ILE B 123
PHE B 173
TYR B 213
LEU B 178
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 117
LEU C 120
LEU C 172
ILE C 151
ALA C 135
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
LEU A  51
LEU A  44
ALA A  30
SER A  13
ALA A  15
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 126
LEU A 140
ILE A 137
ALA A 134
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6wen NSP3
(SARS-CoV-2)		4 / 6
THR A 149
GLU A 120
LYS A   3
PHE A   6
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wen NSP3
(SARS-CoV-2)		4 / 8
PHE A 116
TYR A   9
LEU A 126
LEU A 127
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
LEU A 364
LEU A 368
ILE A 341
SER A 343
ALA A 338
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
LEU A 364
LEU A 368
ILE A 341
SER A 343
ALA A 338
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU A  59
LEU B  91
LEU B  95
ILE B 107
ILE A  68
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
LEU A  59
ALA B 110
ILE A  68
ILE B 107
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  16
LEU A  59
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
LEU A  56
LEU A  60
ALA B 110
ILE A  68
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  12
LEU B  91
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU B  91
VAL A  16
LEU A  13
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  95
LEU A  56
LEU A  60
ALA B 110
ILE A  68
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 9
GLU A  50
LEU B 128
ARG B 190
ALA B 191
ALA B 152
1.56A10.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  95
LEU A  56
LEU A  59
ILE A  68
ALA B 110
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU A 291
LEU A 352
LEU A 353
ILE B 320
ALA A 305
1.67A
None
None
None
None
CL  A 401 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU E 291
LEU E 352
LEU E 353
ILE F 320
ALA E 305
1.67A
None
None
None
None
CL  E 401 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU D 291
LEU D 352
LEU D 353
ILE C 320
ALA D 305
1.65A
None
None
None
None
CL  D 401 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR C7026
ILE C7027
TYR C6813
LEU C6825
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TYR C6845
HIS C6867
ILE C6951
ILE C6967
ALA C6966
1.30A
SAH  C7102 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6967
PHE C6985
TYR C6950
LEU C6981
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C7073
LEU C7078
LEU C7060
ILE C7065
ALA C6960
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
TYR A6950
VAL A6865
LEU A6924
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
THR A7032
MET A6818
LYS A6814
ILE A7027
1.74A
None
None
FMT  A7105 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
SER C6927
ILE C6967
ALA C6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A7026
ILE A7027
TYR A6813
LEU A6825
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6887
LEU A7050
LEU A6852
ILE A6926
SER A6964
1.51A
None
FMT  A7107 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 8
TYR B4283
LEU B4365
VAL B4361
LEU B4328
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6967
TYR C6950
VAL C6865
LEU C6924
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
ILE C6955
SER C6927
ALA C6966
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A6950
VAL A6865
LEU A6924
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 8
TYR D4283
LEU D4365
VAL D4361
LEU D4328
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6955
TYR C6950
VAL C6865
LEU C6924
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TYR A6845
HIS A6867
ILE A6951
ILE A6967
ALA A6966
1.30A
SAH  A7102 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
PHE A6985
TYR A6950
LEU A6981
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ASP B  82
TYR A 172
PHE B  53
TYR B 112
1.77A15.95
 ZN  B 202 (-2.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 109
LEU C 159
ASN D  77
ASP D  82
1.74A15.95
MES  D 201 (-4.6A)
None
None
ZN  D 202 (-2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR A 109
LEU A 159
ASN B  77
ASP B  82
1.77A15.95
MES  B 201 (-4.3A)
None
None
ZN  B 202 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU A 167
PHE A 171
LEU A 161
LEU A 159
ALA A  55
1.52A
None
None
None
None
MES  B 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR A 109
LEU A  56
ASN B  77
ASP B  82
1.72A15.95
MES  B 201 (-4.3A)
None
None
ZN  B 202 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
TYR C 109
LEU C  56
ASN D  77
ASP D  82
1.79A15.95
MES  D 201 (-4.6A)
None
None
ZN  D 202 (-2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LEU B 167
PHE B 171
LEU B 161
LEU B 159
ALA B  55
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
SER C6927
ILE C6967
ALA C6966
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6967
PHE C6985
TYR C6950
LEU C6981
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C7073
LEU C7078
LEU C7060
ILE C7065
ALA C6960
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6955
TYR A6950
VAL A6865
LEU A6924
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
TYR C6845
HIS C6867
ILE C6951
ILE C6967
ALA C6966
1.30A
SFG  C7103 ( 4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A6887
LEU A7050
LEU A6852
ILE A6926
SER A6964
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR C7026
ILE C7027
TYR C6813
LEU C6825
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
LEU C6924
ILE C6955
SER C6927
ALA C6966
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A6950
VAL A6865
LEU A6924
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
PHE A6985
TYR A6950
LEU A6981
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
TYR A6845
HIS A6867
ILE A6951
ILE A6967
ALA A6966
1.31A
SFG  A7103 ( 4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR A7026
ILE A7027
TYR A6813
LEU A6825
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 8
TYR B4283
LEU B4365
VAL B4361
LEU B4328
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6955
TYR C6950
VAL C6865
LEU C6924
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C6887
LEU C7050
LEU C6852
ILE C6926
SER C6964
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 8
TYR D4283
LEU D4365
VAL D4361
LEU D4328
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU C6883
ILE C6866
SER C6927
ILE C6925
ALA C6966
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
THR A7032
MET A6818
LYS A6814
ILE A7027
1.76A
None
None
FMT  A7107 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6967
TYR C6950
VAL C6865
LEU C6924
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
LEU A6887
LEU A7050
LEU A6852
ILE A6926
SER A6964
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ASP B 220
TYR B 226
PHE B 233
TYR B 238
1.77A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
TYR B 226
TYR B 238
PHE B 303
LEU B 251
1.64A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PHE A 135
TYR A 325
VAL A 149
LEU A 152
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ASP A 220
TYR A 226
PHE A 233
TYR A 238
1.79A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
TYR B 238
PHE B 214
VAL B 304
LEU B 300
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PHE B 135
TYR B 325
VAL B 149
LEU B 152
1.34A
None
None
ACT  B 408 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A  97
LEU A  50
VAL A  54
LEU A  58
1.40A
None
None
EDO  A 403 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		6 / 12
PHE A 230
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 219
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.61A
None
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 126
LEU D 140
ILE D 137
ALA D 134
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 126
LEU C 140
ILE C 137
ALA C 134
1.65A
None
APR  C 201 (-4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.43A
None
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.59A
None
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.59A
None
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.41A
None
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.45A
None
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.58A
None
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.43A
None
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6887
LEU A7050
LEU A6852
ILE A6926
SER A6964
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
TYR A6950
VAL A6865
LEU A6924
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A7073
LEU A7078
LEU A7060
ILE A7065
ALA A6960
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6883
ILE A6866
SER A6927
ILE A6925
ALA A6966
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6955
TYR A6950
VAL A6865
LEU A6924
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
TYR A6845
HIS A6867
ILE A6951
ILE A6967
ALA A6966
1.30A
SAH  A7101 (-4.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wq3 NSP10
(SARS-CoV-2)		4 / 8
TYR B4283
LEU B4365
VAL B4361
LEU B4328
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
LEU A6924
ILE A6955
SER A6927
ALA A6966
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A7026
ILE A7027
TYR A6813
LEU A6825
1.40A
None
None
None
GTA  A7102 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU D  91
VAL C  16
LEU C  13
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE C  39
PHE C  49
LEU D  95
LEU D 103
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  16
LEU A  59
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
PHE B  92
LEU A  17
LEU A  20
SER A  61
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  91
PHE D  92
LEU C  17
LEU C  20
SER C  61
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU C  13
VAL C  12
LEU D  91
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU B  91
PHE B  92
LEU A  17
LEU A  20
ALA A  65
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  95
PHE D  92
LEU C  13
LEU C  17
SER C  61
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU C  13
VAL C  16
LEU C  59
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  12
LEU B  91
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
TYR D 149
VAL C  58
LEU C  59
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 107
LEU B  91
VAL A  16
LEU A  13
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 230
PHE A 219
LEU A 287
ILE A 281
ALA A 206
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
LEU A 205
LEU A 250
ALA A 255
ALA A 260
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
ILE A 123
PHE A 173
TYR A 213
LEU A 178
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A 117
LEU A 120
LEU A 172
ILE A 151
ALA A 135
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A 152
LEU A 113
ALA A 114
ILE A 104
SER A 111
1.28A
None
None
None
None
PO4  A 502 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
ILE A 123
TYR A 213
LEU A 178
VAL A 202
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
SER A 262
LEU A 152
ALA A 144
ILE A 104
ALA A 114
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
PHE A 127
TYR A  95
LEU A 117
LEU A 120
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.60A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.54A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ILE A 259
LEU A 205
VAL A 202
LEU A 250
1.77A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.13A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 126
PHE A 140
LEU A 115
VAL A 148
1.79A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PHE A 230
LEU A 208
VAL A 204
LEU A 268
1.71A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 239
LEU A 242
VAL A 202
LEU A 205
1.60A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PHE A 230
LEU A 250
VAL A 202
LEU A 205
1.73A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.25A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.74A19.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE D 107
LEU C  13
VAL C  16
LEU C  59
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE D 107
LEU C  13
VAL C  12
LEU D  91
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  12
LEU B  91
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  59
LEU D  91
ARG D  96
LEU D  95
ILE D 107
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE D 107
LEU D  91
VAL C  16
LEU C  13
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 107
LEU A  13
VAL A  16
LEU A  59
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 107
LEU B  91
VAL A  16
LEU A  13
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
TYR L  92
GLN L  43
LEU L  15
LEU L  84
ALA L  12
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 8
ILE B  51
PHE B  29
TYR C 102
VAL B 108
LEU B   4
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
TYR C  92
GLN C  43
LEU C  15
LEU C  84
ALA C  12
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 400
LEU A 425
ALA A 411
ILE A 410
ALA A 419
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 400
LEU E 425
ALA E 411
ILE E 410
ALA E 419
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 8
ILE H  51
PHE H  29
TYR L 102
VAL H 108
LEU H   4
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 347
TRP A 436
PHE A 338
ILE A 358
SER A 514
1.51A
None
DMS  A 901 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 347
TRP E 436
PHE E 338
ILE E 358
SER E 514
1.52A
None
DMS  E 901 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 8
ILE H  51
PHE H  29
TYR L 102
VAL H 108
LEU H   4
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 400
LEU E 425
ALA E 411
ILE E 410
ALA E 419
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 347
TRP E 436
PHE E 338
ILE E 358
SER E 514
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 8
ILE H  51
PHE H  29
TYR L 102
VAL H 108
LEU H   4
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 8
ILE B  51
PHE B  29
TYR C 102
VAL B 108
LEU B   4
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
TYR L  92
GLN L  43
LEU L  15
LEU L  84
ALA L  12
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
TYR C  92
GLN C  43
LEU C  15
LEU C  84
ALA C  12
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TYR C 179
TYR C 146
VAL C  13
LEU C  84
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 400
LEU E 425
ALA E 411
ILE E 410
ALA E 419
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
TYR L 179
TYR L 146
VAL L  13
LEU L  84
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 400
LEU A 425
ALA A 411
ILE A 410
ALA A 419
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 347
TRP A 436
PHE A 338
ILE A 358
SER A 514
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.22A
None
None
PEG  A 404 (-2.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.42A
None
None
None
None
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.44A
None
None
None
None
EDO  C 208 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 126
LEU D 140
ILE D 137
ALA D 134
1.64A
None
None
None
None
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.53A
None
None
None
None
EDO  D 211 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.55A
None
None
None
None
EDO  C 208 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.66A
None
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 126
LEU A 140
ILE A 137
ALA A 134
1.65A
None
APR  A 201 (-4.8A)
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 134
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.46A
None
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.42A
None
None
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.66A
None
APR  B 201 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 126
LEU C 140
ILE C 137
ALA C 134
1.64A
None
APR  C 201 (-4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 129
1.65A
None
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 129
1.47A
None
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.49A
None
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.55A
None
None
None
None
EDO  A 204 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 129
1.65A
None
None
None
None
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 129
1.48A
None
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 164
ILE D 137
SER D 139
ALA D 129
1.67A
None
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.48A
None
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 160
LEU D 126
LEU D 140
ILE D 137
ALA D 134
1.67A
None
APR  D 201 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 129
1.66A
None
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 160
LEU E 164
ILE E 137
SER E 139
ALA E 134
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 126
LEU B 140
ILE B 137
ALA B 134
1.63A
None
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.44A
None
None
EDO  A 206 (-4.6A)
None
EDO  A 205 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PHE A 156
TYR B 161
LEU B 140
VAL B 144
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.53A
EDO  C 203 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.40A
None
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 160
LEU C 164
ILE C 137
SER C 139
ALA C 134
1.41A
EDO  C 203 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 160
LEU B 164
ILE B 137
SER B 139
ALA B 134
1.51A
None
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 160
LEU A 164
ILE A 137
SER A 139
ALA A 134
1.57A
None
None
EDO  A 206 (-4.6A)
None
EDO  A 205 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		6 / 12
LEU A 208
PHE A 219
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
PHE A 219
LEU A 205
ILE A 259
ALA A 266
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 134
LEU A 146
LEU A 142
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP7
(SARS-CoV-2)		4 / 6
THR C  46
GLU C  47
MET C   3
ILE C  39
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU C  13
VAL C  12
LEU D  91
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
LEU A 576
ILE A 589
ALA A 688
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
PHE A 745
TYR A 732
LEU A 708
LEU A 707
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
PHE A 222
TYR A 238
VAL A  96
LEU A  90
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 479
ILE A 696
TYR A 483
VAL A 605
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 10
TYR A 453
ILE A 450
MET A 666
LEU A 388
VAL A 398
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
ASP A 218
TYR A 217
TYR A  87
LEU A  90
1.14A17.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU D  91
VAL C  16
LEU C  13
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 7
TYR A 237
LEU A 207
ASN A 209
TYR A 732
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ILE A 579
ILE A 589
ALA A 688
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
ILE A 579
ILE A 589
ALA A 688
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE C  39
PHE C  49
LEU D  95
LEU D 103
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		6 / 12
PHE A 157
TRP A 162
LEU A 142
LEU A 146
LEU A 178
ILE A 244
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 157
LEU A 131
LEU A 142
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 480
LEU A 576
ALA A 580
ILE A 579
ALA A 688
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 480
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 10
TYR A 732
PHE A 471
TYR A 788
LEU A 708
LEU A 727
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ALA A 580
ILE A 579
ALA A 688
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 589
PHE A 480
LEU A 576
LEU A 575
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A 884
PHE A 419
TYR A 921
LEU A 891
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
TYR A 209
ILE A 259
PHE A 219
VAL A 204
LEU A 208
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 230
LEU A 268
LEU A 287
ILE A 281
ALA A 206
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
LEU A 208
LEU A 205
ALA A 260
ILE A 259
ALA A 266
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 134
LEU A 146
LEU A 142
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ALA A 580
ILE A 579
ALA A 688
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
TYR A 237
LEU A 207
ASN A 209
TYR A 732
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
LEU A 576
ILE A 579
ILE A 589
ALA A 688
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
LEU A 247
ARG A 249
ILE A 171
ALA A 176
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
TYR A 453
ILE A 450
MET A 666
LEU A 388
VAL A 398
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_B_P1ZB2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
TYR A 149
LEU A 131
LEU A 127
ARG A 181
ALA A 185
1.80A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 527
LEU A 372
ALA A 502
ILE A 562
ALA A 376
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU D  95
LEU C  13
LEU C  59
SER C  57
ILE D 106
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
PHE A 222
TYR A 238
VAL A  96
LEU A  90
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 107
LEU D  91
VAL C  16
LEU C  13
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
PHE A 157
TRP A 162
LEU A 142
LEU A 146
LEU A 178
ILE A 244
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 479
ILE A 696
TYR A 483
VAL A 605
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
SER A 682
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASP A 484
PHE A 480
TYR A 483
LEU A 638
1.70A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 157
LEU A 131
LEU A 142
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
SER A 236
LEU A 723
LEU A 707
ILE A 715
ALA A  43
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 575
PHE A 480
LEU A 576
SER A 759
ALA A 690
1.55A
None
None
None
U  P  20 ( 2.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 171
PHE A 134
LEU A 146
LEU A 142
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
PHE A 157
TRP A 162
LEU A 142
LEU A 146
LEU A 178
ILE A 244
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
ILE A 579
ILE A 589
ALA A 688
1.46A
 U  T  10 (-2.9A)
None
None
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
SER A 682
LEU A 638
LEU A 576
ILE A 589
ALA A 688
1.62A
 U  T  10 (-2.9A)
None
None
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 453
ILE A 450
LEU A 388
VAL A 398
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
TYR A 884
LEU A 885
LYS A 890
ASP A 893
1.80A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		6 / 12
PHE A 506
LEU B  91
PHE A 340
ILE A 333
SER A 343
ALA A 379
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
SER A 682
LEU A 638
ALA A 580
ILE A 579
ILE A 589
ALA A 688
1.59A
 U  T  10 (-2.9A)
None
A  T  13 ( 3.7A)
None
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 480
LEU A 576
ALA A 580
ILE A 579
ALA A 688
1.49A
None
None
A  T  13 ( 3.7A)
None
F86  P 102 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 745
TYR A 732
LEU A 708
LEU A 707
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 479
ILE A 696
TYR A 483
VAL A 605
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ASP A 484
PHE A 480
TYR A 483
LEU A 638
1.65A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
LEU A 247
ARG A 249
ILE A 171
ALA A 176
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 222
TYR A 237
VAL A  96
LEU A  90
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 450
TYR A 455
LEU A 544
VAL A 410
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
TYR A 453
ILE A 450
MET A 666
LEU A 388
VAL A 398
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
TYR A 237
LEU A 207
ASN A 209
TYR A 732
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 638
PHE A 480
ALA A 580
ILE A 579
ALA A 688
1.25A
None
None
A  T  13 ( 3.7A)
None
F86  P 102 ( 4.1A)