Ligand ID: 6ZP


Drugbank ID:
DB08883
(Perampanel)


Indication:
Used in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.

Get human targets for 6ZP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '6ZP'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.43A17.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
PHE A 103
ASP A 176
ASN A  84
LEU A  86
SER A 147
1.38A17.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER A  10
TYR A 126
SER A 121
SER B1113
1.27A17.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.33A17.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
PHE A 103
ASP A 176
ASN A  84
LEU A  86
SER A 147
1.40A17.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER A  10
TYR A 126
SER A 121
SER B 113
1.36A17.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
SER C 246
TYR C 306
SER C 116
ASN C 263
1.42A18.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 7
PRO N 100
TYR N 126
PHE N  68
ASN N 105
1.30A10.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 9
SER D 163
SER D 160
LEU D 136
PHE D 203
ASN D 225
1.79A14.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.38A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 8
ASP A 133
PRO A 134
SER A  98
SER A 175
1.41A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		2xyr NSP10
(SARSr-CoV)		4 / 7
PRO B 100
TYR B 126
PHE B  68
ASN B 105
1.45A9.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 8
ASP A 133
PRO A 134
SER A  98
SER A 175
1.30A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3atw 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.34A17.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		4 / 8
TYR A 352
PHE A 361
SER A 386
SER A 358
1.40A13.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 352
PHE F 361
SER F 386
SER F 358
1.37A12.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.41A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.42A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
SER A 147
ASN A 142
LEU A 141
SER A 121
ASN A  28
1.69A16.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
PHE A 103
ASP A 176
ASN A  84
LEU A  86
SER A 147
1.52A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		3i6g BETA-2-MICROGLOBULIN
HLA, A-2
(Homo
sapiens)		5 / 10
SER D  38
PHE D  22
ASP D  37
LEU E  54
SER D  13
1.78A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		3i6l BETA-2-MICROGLOBULIN
HLA, A-24
(Homo
sapiens)		5 / 10
SER D  38
PHE D  22
ASP D  37
LEU E  54
SER D  13
1.70A15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.41A17.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 8
SER A 201
TYR A 228
ASN A 198
SER A 175
1.41A17.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		3r24 NSP10 AND NSP11
(SARSr-CoV)		4 / 7
PRO B 100
TYR B 126
PHE B  68
ASN B 105
1.50A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 8
TYR F 491
PHE B  40
ASN B  33
SER B  44
1.41A14.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3scj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 352
PHE F 361
SER F 386
SER F 358
1.43A11.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		3vb4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER A  10
TYR A 126
SER A 121
SER B 113
1.37A17.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER A  10
TYR A 126
SER A 121
SER B 113
1.36A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		4 / 7
SER A 115
PRO A  97
PHE A  96
ASN A 111
1.50A18.50
OCS  A 112 ( 4.3A)
None
None
OCS  A 112 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
SER A  10
TYR A 126
SER A 121
SER B 113
1.35A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
SER B 418
PHE B 506
SER B 407
ASN B 410
1.51A21.51
None
G3A  B 606 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
SER D 418
PHE D 506
SER D 407
ASN D 410
1.43A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5c8u NSP10
(SARSr-CoV)		4 / 8
PRO C 100
TYR C 126
PHE C  68
ASN C 105
1.40A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
SER A 418
PHE A 506
SER A 407
ASN A 410
1.36A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
PRO P 100
TYR P 126
PHE P  68
ASN P 105
1.33A10.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
SER B 503
PHE B 506
ASN B 408
LEU B 409
SER B 307
1.78A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.65A12.72
None
DMS  A 402 (-3.8A)
None
DMS  A 402 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
SER B 115
PRO B  97
PHE B  96
ASN B 111
1.44A17.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5x4r S PROTEIN
(MERS-CoV)		4 / 7
PRO A 196
TYR A 201
PHE A 228
SER A 294
1.41A16.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 10
SER A 165
ASP A 166
PHE A 168
SER A 120
ASN A 122
1.65A22.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 7
SER A 165
ASP A 166
PHE A 168
ASN A 122
1.28A22.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		5x5f S PROTEIN
(MERS-CoV)		4 / 7
PRO C 196
TYR C 201
PHE C 228
SER C 294
1.41A20.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR B 352
PHE B 361
SER B 386
SER B 358
1.25A21.93
TYR  B 352 ( 1.3A)
PHE  B 361 ( 1.3A)
SER  B 386 ( 0.0A)
SER  B 358 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
SER A 246
TYR A 306
SER A 116
ASN A 263
1.38A18.53
None
GOL  A 408 (-4.9A)
NA  A 404 (-3.7A)
NA  A 404 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
SER A 949
ASP B 557
TYR A  53
SER C 740
1.22A21.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR C 352
PHE C 361
SER C 386
SER C 358
1.20A21.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ASP C 191
TYR C 195
ASN C 189
PHE A 451
SER A 500
1.64A21.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
SER C 556
ASP C 557
ASN A 838
SER A 950
1.36A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
SER A 949
ASP C 557
TYR A  53
SER B 740
1.24A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
SER B 798
ASP B 802
ASN B 806
LEU B 920
SER B 914
1.70A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
ASP A 191
PRO C 413
PHE C 416
SER C 380
1.15A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR B 365
PHE B 374
SER B 399
SER B 371
1.39A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER B 438
ASP B 442
PHE B 497
ASN B 437
1.46A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		5 / 10
SER E 438
ASP E 442
TYR E 495
ASN E 450
PHE E 347
1.27A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		5 / 9
SER E 438
ASP E 442
TYR E 495
PHE E 347
SER E 375
1.51A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		5 / 9
SER F 438
ASP F 442
TYR F 495
PHE F 347
SER F 375
1.71A15.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m18 ACE2
(Homo
sapiens)		4 / 8
SER D 721
TYR D 633
SER D 709
ASN D 712
1.34A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER B 123
TYR B 126
SER D 301
SER D 113
1.72A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR C 239
PHE C 219
SER C 284
SER C 267
1.72A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER D 113
PHE D 305
SER D 158
SER B 123
1.46A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER C  10
TYR C 126
SER C 121
SER A 113
1.37A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PRO D   9
PHE D   8
SER D 301
SER D 113
1.70A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER B  10
TYR B 126
SER B 121
SER D 113
1.36A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ASP D 295
PHE D 294
SER D 158
ASN D 151
1.79A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER C 113
PHE C 305
SER C 158
SER A 123
1.45A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR A 126
PHE C   8
SER C 301
SER C 113
1.74A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PRO A   9
SER A 158
ASN A 151
SER C 121
1.68A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
TYR B 126
PHE D   8
SER D 301
SER D 113
1.76A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
ASP A 295
PHE A 294
SER A 158
ASN A 151
1.77A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
PRO C   9
PHE C   8
SER C 301
SER C 113
1.70A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER D  10
TYR D 126
SER D 121
SER B 113
1.61A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
SER A  10
TYR A 126
SER A 121
SER C 113
1.36A17.31

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
SER A 784
TYR A 129
SER A 778
ASN A 781
1.75A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		5 / 9
SER A 434
SER A 835
ASP A 833
PRO A 832
LEU A 869
1.54A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
SER A 564
PRO A 537
TYR A 346
SER A 681
1.39A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
SER A 835
ASP A 833
PRO A 832
SER A 433
1.75A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 664
PHE A 326
ASN A 628
SER A 325
1.51A22.26

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 8
SER A 343
TYR A 273
PHE A 348
ASN A 356
1.43A22.26

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6m71 NSP12
(SARS-CoV-2)		4 / 7
ASP A 477
TYR A 746
PHE A 480
SER A 578
1.78A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
TYR C 197
PHE C 193
SER A 380
ASN A 505
1.13A22.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6nur NSP12
(SARSr-CoV)		5 / 9
SER A 434
SER A 835
ASP A 833
PRO A 832
LEU A 869
1.56A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6nur NSP12
(SARSr-CoV)		5 / 10
SER A 318
PHE A 317
TYR A 294
ASN A 297
PHE A 275
1.78A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6nur NSP12
(SARSr-CoV)		4 / 8
SER A 343
TYR A 273
PHE A 348
ASN A 356
1.36A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6nus NSP12
(SARSr-CoV)		4 / 7
SER A 564
PRO A 537
TYR A 346
SER A 681
1.41A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER A 438
ASP A 442
TYR A 495
ASN A 450
PHE A 347
1.57A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER B1051
SER B1030
LEU B1024
PHE B1062
SER B1037
1.78A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
PHE A 497
ASN A 437
1.38A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 810
ASP A 808
PRO A 807
SER A 803
1.39A21.99
None
None
None
NAG  A1307 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 365
PHE E 374
SER E 399
SER E 371
1.40A15.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASP A 442
PHE A 347
SER A 375
ASN A 437
1.26A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER C 438
ASP C 442
ASN C 450
PHE C 497
ASN C 439
1.78A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER C 555
SER A  45
TYR A  38
LEU C 560
PHE C 559
1.61A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR C 365
PHE C 374
SER C 399
SER C 371
1.29A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
SER H 130
PRO H 126
SER L 114
SER H 188
1.80A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 365
PHE C 374
SER C 399
SER C 371
1.64A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
ASP H 101
PRO H 100
TYR L  91
SER H  96
1.58A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
SER C 438
ASP C 442
SER C 375
ASN C 437
1.59A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
SER C 438
ASP C 442
PHE C 497
ASN C 437
1.60A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
SER C 438
ASP C 442
TYR C 495
SER C 399
1.72A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
PRO L 120
TYR L 186
PHE L 118
SER H 128
1.72A11.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
SER H 120
ASP H 144
SER H 203
SER H 173
1.69A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
SER C 438
ASP C 442
PHE C 497
ASN C 437
1.48A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
SER H  85
ASP H  86
SER H 113
SER H  82
1.68A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 9
SER C 438
ASP C 442
TYR C 495
PHE C 347
SER C 375
1.58A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 7
SER C 438
ASP C 442
TYR C 495
PHE C 347
1.56A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w4h NSP16
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.40A16.89
ACT  A7103 (-2.6A)
None
ACT  A7103 (-3.3A)
ACT  A7104 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6973
TYR A6979
SER A6999
SER A6927
1.63A11.57
EDO  A7102 ( 4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASP A6931
PRO A6932
SER A6896
SER A6973
1.30A11.57
EDO  A7102 (-4.6A)
None
None
EDO  A7102 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w61 NSP10
(SARS-CoV-2)		4 / 7
PRO B4353
TYR B4379
PHE B4321
ASN B4358
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.38A11.57
None
None
None
EDO  A7102 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ASP A 295
PHE A 294
SER A 158
ASN A 151
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C6973
TYR C6979
SER C6999
SER C6927
1.65A11.75
None
None
FMT  C7108 ( 2.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A6973
TYR A6979
SER A6999
SER A6927
1.66A11.75
None
None
FMT  A7104 ( 2.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP A6931
PRO A6932
SER A6896
SER A6973
1.45A11.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6931
PRO C6932
SER C6896
SER C6973
1.35A11.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP10
(SARS-CoV-2)		4 / 7
PRO D4353
TYR D4379
PHE D4321
ASN D4358
1.61A10.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.40A11.75
FMT  A7104 ( 2.9A)
None
FMT  A7104 ( 3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP10
(SARS-CoV-2)		4 / 7
PRO B4353
TYR B4379
PHE B4321
ASN B4358
1.56A10.38
None
None
None
NA  B4403 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
SER C6999
TYR C7026
ASN C6996
SER C6973
1.39A11.75
FMT  C7108 ( 2.7A)
None
FMT  C7108 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ASP C6931
PRO C6932
ASN C6899
SER C6973
1.42A11.75
None
None
SAM  C7105 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
SER B 245
TYR B 273
PHE B 304
SER B 170
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
SER A 245
TYR A 273
PHE A 304
SER A 170
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
SER A 245
TYR A 273
PHE A 304
SER A 170
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
SER C 245
TYR C 273
PHE C 304
SER C 170
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wey NSP3
(SARS-CoV-2)		4 / 8
ASP A 349
TYR A 317
PHE A 372
ASN A 219
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
SER E 318
PHE F 314
SER E 312
SER F 318
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
SER B 318
PHE A 314
SER B 312
SER A 318
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.40A
FMT  A7104 (-3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6973
TYR A6979
SER A6999
SER A6927
1.66A
None
None
FMT  A7104 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER C6999
TYR C7026
ASN C6996
SER C6973
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER C6973
TYR C6979
SER C6999
SER C6927
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wjt NSP10
(SARS-CoV-2)		4 / 7
PRO B4353
TYR B4379
PHE B4321
ASN B4358
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
SER D 105
TYR D 109
PHE D 171
SER A  79
1.59A
None
None
None
ZN  A 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
SER B 105
TYR B 109
PHE B 171
SER C  79
1.52A
None
None
None
ZN  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP10
(SARS-CoV-2)		4 / 7
PRO B4353
TYR B4379
PHE B4321
ASN B4358
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6931
PRO C6932
ASN C6899
SER C6973
1.58A
None
None
SFG  C7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
SER C6999
TYR C7026
ASN C6996
SER C6973
1.38A
FMT  C7110 ( 3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.41A
FMT  A7106 ( 3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ASP C6931
PRO C6932
SER C6896
SER C6973
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
SER A6973
TYR A6979
SER A6999
SER A6927
1.65A
None
None
FMT  A7106 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP16
(SARS-CoV-2)		4 / 8
SER C6973
TYR C6979
SER C6999
SER C6927
1.64A
None
None
FMT  C7110 ( 3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wkq NSP10
(SARS-CoV-2)		4 / 7
PRO D4353
TYR D4379
PHE D4321
ASN D4358
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP B 324
TYR B 179
ASN B  74
SER B 198
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ASP A 324
TYR A 179
ASN A  74
SER A 198
1.58A
None
None
EDO  A 406 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
ASP A 295
PHE A 294
SER A 158
ASN A 151
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASP A 145
TYR A 113
PHE A 168
ASN A  15
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASP D 145
TYR D 113
PHE D 168
ASN D  15
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6973
TYR A6979
SER A6999
SER A6927
1.63A
None
None
GTA  A7102 (-2.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
SER A6999
TYR A7026
ASN A6996
SER A6973
1.40A
GTA  A7102 (-2.5A)
None
GTA  A7102 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
SER A 245
TYR A 273
PHE A 304
SER A 170
1.52A
None
GOL  A 508 (-4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
SER A 245
TYR A 273
PHE A 304
SER A 170
1.59A
None
GOL  A 508 (-4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
SER B  10
TYR B 126
SER B 121
SER A 113
1.32A17.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.69A12.34
None
DMS  A 403 (-3.8A)
None
DMS  A 403 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 239
PHE A 219
SER A 284
SER A 267
1.52A12.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER E 438
ASP E 442
TYR E 495
ASN E 448
SER E 399
1.76A14.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
SER A 366
ASP A 364
PRO A 527
SER L  62
1.72A
None
None
None
MLI  B 303 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
PHE L 124
SER L 180
ASN L 143
SER H 131
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER E 438
ASP E 442
TYR E 495
PHE E 347
SER E 375
1.64A14.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP H 107
PRO H 105
TYR L  97
SER H 100
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 530
PRO A 527
TYR A 365
ASN A 334
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP C 191
TYR C 198
SER C 162
ASN C 164
1.72A
MLI  C 305 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
SER H  89
TYR H  94
SER H  85
SER H  63
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
TYR A 495
PHE A 347
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
SER A 375
ASN A 437
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
TYR E 495
SER E 399
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
TYR E 495
PHE E 347
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP L 191
TYR L 198
SER L 162
ASN L 164
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 365
PHE E 374
SER E 399
SER E 371
1.44A
None
DMS  E 901 (-4.4A)
None
DMS  E 901 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
PHE A 497
ASN A 437
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
SER B  89
TYR B  94
SER B  85
SER B  63
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP B 107
PRO B 105
TYR C  97
SER B 100
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER A 438
ASP A 442
TYR A 495
PHE A 347
SER A 375
1.63A14.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
SER E 375
ASN E 437
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 438
ASP A 442
TYR A 495
SER A 399
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 365
PHE A 374
SER A 399
SER A 371
1.51A
None
DMS  A 901 (-4.3A)
None
DMS  A 901 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 438
ASP A 442
PHE A 497
ASN A 437
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
PRO B  53
TYR B  52
SER L 174
SER B  71
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
SER B 124
ASP B 148
SER B 207
SER B 177
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
SER E 366
ASP E 364
PRO E 527
SER C  62
1.72A
None
None
None
MLI  B 303 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 365
PHE E 374
SER E 399
SER E 371
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER E 438
ASP E 442
TYR E 495
PHE E 347
SER E 375
1.59A14.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER E 438
ASP E 442
TYR E 495
ASN E 448
SER E 399
1.77A14.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
PHE L 124
SER L 180
ASN L 143
SER H 131
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
TYR E 495
SER E 399
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP H 107
PRO H 105
TYR L  97
SER H 100
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
SER H  89
TYR H  94
SER H  85
SER H  63
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
PRO L 126
TYR L 192
PHE L 124
SER H 132
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
TYR E 495
PHE E 347
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
SER E 375
ASN E 437
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
ASP L 191
TYR L 198
SER L 162
ASN L 164
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
SER H 124
ASP H 148
SER H 207
SER H 177
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 375
SER E 438
ASN E 437
SER E 371
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
ASP A 295
PHE A 294
SER A 158
ASN A 151
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR H 149
PHE A 486
SER H 176
SER H 119
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
SER B  89
TYR B  94
SER B  85
SER B  63
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 438
ASP A 442
PHE A 497
ASN A 437
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 8
ASP B 107
PRO B 105
TYR C  97
SER B 100
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
PHE A 497
ASN A 437
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER A 438
ASP A 442
TYR A 495
SER A 399
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER E 438
ASP E 442
TYR E 495
PHE E 347
SER E 375
1.64A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 365
PHE E 374
SER E 399
SER E 371
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
ASP L 191
TYR L 198
SER L 162
ASN L 164
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 8
ASP C 191
TYR C 198
SER C 162
ASN C 164
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
SER A 438
ASP A 442
TYR A 495
PHE A 347
SER A 375
1.65A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
SER H  89
TYR H  94
SER H  85
SER H  63
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER A 438
ASP A 442
TYR A 495
ASN A 448
SER A 399
1.76A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 365
PHE A 374
SER A 399
SER A 371
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
SER E 375
ASN E 437
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
SER E 438
ASP E 442
TYR E 495
ASN E 448
SER E 399
1.75A14.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
TYR E 495
SER E 399
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 8
PHE L 124
SER L 180
ASN L 143
SER H 131
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
SER E 438
ASP E 442
PHE E 497
ASN E 437
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
TYR A 495
PHE A 347
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 8
PHE C 124
SER C 180
ASN C 143
SER B 131
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER E 438
ASP E 442
TYR E 495
PHE E 347
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 8
ASP H 107
PRO H 105
TYR L  97
SER H 100
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
SER A 438
ASP A 442
SER A 375
ASN A 437
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
TYR A 239
PHE A 219
SER A 284
SER A 267
1.57A
PEG  A 404 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO A   9
PHE A   8
SER A 301
SER A 113
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASP D 145
TYR D 113
PHE D 168
ASN D  15
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASP E 145
TYR E 113
PHE E 168
ASN E  15
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASP E  14
TYR E  17
PHE D   6
ASN D 150
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASP A 145
TYR A 113
PHE A 168
ASN A  15
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASP C 145
TYR C 113
PHE C 168
ASN C  15
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		7btf NSP12
(SARS-CoV-2)		5 / 9
SER A 434
SER A 835
ASP A 833
PRO A 832
LEU A 869
1.42A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
ASP A 235
TYR A  38
ASN A 734
SER A 239
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		7btf NSP12
(SARS-CoV-2)		4 / 7
SER A 564
PRO A 537
TYR A 346
SER A 681
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_D_6ZPD902_1
(GLUTAMATE RECEPTOR 2)		7btf NSP12
(SARS-CoV-2)		5 / 10
SER A 318
PHE A 317
TYR A 294
ASN A 297
PHE A 275
1.80A22.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7btf NSP12
(SARS-CoV-2)		4 / 8
SER A 664
PHE A 326
ASN A 628
SER A 325
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
SER A 664
PHE A 326
ASN A 628
SER A 325
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
SER A 564
PRO A 537
TYR A 346
SER A 681
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_B_6ZPB902_1
(GLUTAMATE RECEPTOR 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
SER A 434
SER A 835
ASP A 833
PRO A 832
LEU A 869
1.57A21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv1 NSP12
NSP7
NSP8
(SARS-CoV-2)		4 / 8
SER B 164
ASP B 163
ASN A 404
SER C  24
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
SER A 343
TYR A 273
PHE A 348
ASN A 356
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 343
TYR A 273
PHE A 348
ASN A 356
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 564
PRO A 537
TYR A 346
SER A 681
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
SER A 784
TYR A 129
SER A 778
ASN A 781
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
SER A 564
PRO A 537
TYR A 346
SER A 681
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
SER A 664
PHE A 326
ASN A 628
SER A 325
1.60A
None