Ligand ID: HQE


Drugbank ID:
DB09526
(Hydroquinone)


Indication:
Hydroquinone is used as an OTC topical lightening agent for disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots and freckles.

Get human targets for HQE in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'HQE'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.10A19.80
MPD  A 307 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.47A22.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		1yo4 HYPOTHETICAL PROTEIN
X4
(SARSr-CoV)		5 / 10
LEU A  16
LEU A  62
THR A  44
THR A  46
VAL A  14
1.46A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
LEU B1250
VAL B1261
LEU B1202
THR B1201
VAL B1247
1.47A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 7
HIS A 268
HIS A 276
ASN A 219
ALA A 271
1.64A19.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 7
HIS A 268
HIS A 276
ASN A 219
ALA A 271
1.62A19.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 10
VAL C  16
LEU F  96
THR F  94
THR F  98
VAL B  21
1.46A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 10
VAL G 164
LEU G 189
VAL G 191
THR G 146
VAL G 137
1.32A22.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		2ajf ACE2
(Homo
sapiens)		4 / 7
HIS A 373
ASN A 546
HIS A 417
ALA A 412
1.42A17.77
None
NAG  A1546 (-1.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		2ajf ACE2
(Homo
sapiens)		4 / 7
HIS A 373
ASN A 546
HIS A 417
ALA A 412
1.38A17.77
None
NAG  A1546 (-1.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.12A21.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL B  77
PHE B  66
LEU B  89
VAL B  91
VAL B  36
1.46A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 7
HIS A  87
HIS A  95
ASN A  38
ALA A  90
1.66A18.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		4 / 7
HIS B  87
HIS B  46
ASN B  38
HIS B  95
1.63A18.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
PHE E 364
LEU C 377
LEU E 499
PHE E 501
ASP E 376
1.56A19.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE E 345
PHE E 329
LEU E 421
PHE E 364
1.10A19.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
PHE E 379
LEU E 499
LEU E 421
THR E 363
VAL E 498
1.35A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 10
LEU B 165
VAL B 161
LEU B 136
THR B 134
THR B 135
1.47A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.13A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		5 / 10
VAL A  52
PHE A  54
VAL A  62
LEU A  36
VAL A  86
1.30A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A23.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 8
ILE A 222
LEU A 227
LEU A 299
PHE A 302
1.18A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
ILE A  71
PRO A  67
LEU A  75
LEU A 122
ASP A  78
1.74A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
ILE B 200
TYR B 239
LEU B 242
PHE B 230
1.18A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.20A20.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A23.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A23.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.21A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
PHE C 232
LEU C 227
TYR C 225
LEU C 299
ASP C 212
1.75A21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 7
ASN B 142
HIS B 163
VAL B 171
ALA B 173
1.78A19.34
None
XP1  B1304 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
ILE B 200
TYR B 239
LEU B 242
PHE B 230
1.13A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 7
ASN B 142
HIS B 163
VAL B 171
ALA B 173
1.79A19.34
None
XP1  B1304 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		2z3d REPLICASE
POLYPROTEIN 1AB
(PP1AB)
(SARSr-CoV)		4 / 7
HIS A  41
HIS A 164
HIS A 163
ALA I 904
1.53A20.37
OCQ  I 905 (-3.5A)
None
OCQ  I 905 (-3.8A)
OCQ  I 905 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		2z3d REPLICASE
POLYPROTEIN 1AB
(PP1AB)
(SARSr-CoV)		4 / 7
HIS A  41
HIS A 164
HIS A 163
ALA I 904
1.50A20.37
OCQ  I 905 (-3.5A)
None
OCQ  I 905 (-3.8A)
OCQ  I 905 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
HIS A 239
ASN A 601
VAL A 604
ALA A 242
1.38A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
HIS A 373
ASN A 546
HIS A 417
ALA A 412
1.35A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3e9s NSP3
(SARSr-CoV)		5 / 10
VAL A 206
PHE A 242
LEU A 179
LEU A 174
THR A 171
1.38A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE B 200
TYR B 239
LEU B 242
PHE B 230
1.12A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.13A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
ILE B 200
TYR D 239
LEU D 242
PHE D 230
1.14A13.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 172
HIS B 163
ASN B  28
ALA B 140
1.51A20.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 172
HIS B 163
ASN B  28
ALA B 140
1.48A20.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.13A20.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.44A23.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 172
HIS B 163
ASN B  28
ALA B 140
1.63A21.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 172
HIS B 163
ASN B  28
ALA B 140
1.60A21.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.45A23.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.44A23.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.15A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.40A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL B  77
PHE B  66
LEU B  89
VAL B  91
VAL B  36
1.46A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE B 200
TYR B 239
LEU B 242
PHE B 230
1.10A18.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE B 200
TYR B 239
LEU B 242
PHE B 230
1.12A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
VAL A 117
PHE A 148
LEU A 121
LEU A 173
THR A 171
1.46A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
HIS A 239
ASN A 601
VAL A 604
ALA A 242
1.31A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
HIS A 239
ASN A 601
VAL A 604
ALA A 242
1.29A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A23.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		3to2 MHC CLASS I ANTIGEN
(Homo
sapiens)		4 / 7
HIS A  70
HIS A  74
VAL A  67
ALA A  24
1.49A20.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		3to2 MHC CLASS I ANTIGEN
(Homo
sapiens)		4 / 7
HIS A  70
HIS A  74
VAL A  67
ALA A  24
1.48A20.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		3vb6 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.09A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.18A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 176
HIS B  74
ASN B 129
ALA B 132
1.65A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		4 / 7
HIS B 176
HIS B  74
ASN B 129
ALA B 132
1.66A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL B  77
PHE B  66
LEU B  89
VAL B  91
VAL B  36
1.44A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		4twy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.17A19.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.47A23.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
ILE A 200
TYR A 239
LEU A 242
PHE A 230
1.18A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
HIS B 148
ASN B 266
VAL B 269
ALA B 270
1.70A19.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
HIS B 148
ASN B 266
VAL B 269
ALA B 270
1.66A19.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 5
ILE B  14
GLN B  22
ARG B  53
GLU B 128
1.73A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 7
HIS A  80
HIS A  83
ASN B 130
ALA A  71
1.50A20.69
None
ZN  A 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
HIS B 148
ASN B 266
VAL B 269
ALA B 270
1.49A19.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 7
HIS B 148
ASN B 266
VAL B 269
ALA B 270
1.54A19.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
HIS D 176
HIS D  74
ASN D 129
ALA D 132
1.65A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
HIS D 176
HIS D  74
ASN D 129
ALA D 132
1.64A19.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5f22 NSP8
(SARSr-CoV)		5 / 10
VAL B 164
LEU B 189
VAL B 191
THR B 146
VAL B 137
1.40A21.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
ASN A 104
HIS M   0
VAL A 101
ALA M   1
1.48A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 7
HIS B 148
ASN B 266
VAL B 269
ALA B 270
1.77A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.45A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.53A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
LEU A  30
VAL A  18
LEU A  32
THR A  98
VAL A  36
1.78A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A  74
LEU A  89
VAL A  91
VAL A  36
TRP A  31
1.69A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.79A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
HIS B 176
HIS B  74
ASN B 129
ALA B 132
1.72A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
VAL B 206
PHE B 242
LEU B 179
LEU B 174
THR B 171
1.38A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
ASN C 627
HIS C 641
VAL C 675
ALA C 676
1.60A13.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
ASN C 627
HIS C 641
VAL C 675
ALA C 676
1.61A13.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
ILE A 637
LEU A 597
LEU A 615
PHE A 305
1.16A16.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		5x5c S PROTEIN
(MERS-CoV)		4 / 7
ASN C 342
HIS C 670
VAL C 661
ALA C 671
1.63A11.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		5x5c S PROTEIN
(MERS-CoV)		4 / 7
ASN C 342
HIS C 670
VAL C 661
ALA C 671
1.63A11.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
ILE A 962
ASP A 961
LEU A 966
LEU B 377
PHE B 379
1.62A16.93
ILE  A 962 ( 0.7A)
ASP  A 961 ( 0.5A)
LEU  A 966 ( 0.6A)
LEU  B 377 ( 0.6A)
PHE  B 379 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 10
VAL C 497
PHE C 329
LEU C 421
VAL C 496
LEU C 499
VAL C 420
1.77A12.14
VAL  C 497 ( 0.6A)
PHE  C 329 ( 1.3A)
LEU  C 421 ( 0.5A)
VAL  C 496 ( 0.6A)
LEU  C 499 ( 0.6A)
VAL  C 420 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE A 962
ASP A 961
LEU A 966
LEU B 377
PHE B 379
1.65A16.93
ILE  A 962 ( 0.7A)
ASP  A 961 ( 0.5A)
LEU  A 966 ( 0.6A)
LEU  B 377 ( 0.6A)
PHE  B 379 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE A 962
ASP A 961
LEU A 966
LEU B 377
PHE B 379
1.64A16.93
ILE  A 962 ( 0.7A)
ASP  A 961 ( 0.5A)
LEU  A 966 ( 0.6A)
LEU  B 377 ( 0.6A)
PHE  B 379 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 10
VAL A 206
PHE A 242
LEU A 179
LEU A 174
THR A 171
1.43A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
PHE B 364
LEU B 355
TYR B 352
LEU B 499
PHE B 501
1.52A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6acg ACE2
(Homo
sapiens)		4 / 7
HIS D 239
ASN D 601
VAL D 604
ALA D 242
1.25A17.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		6acg ACE2
(Homo
sapiens)		5 / 9
ILE D 256
PRO D 490
LEU D 266
LEU D 162
ASP D 157
1.67A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6acg ACE2
(Homo
sapiens)		4 / 7
HIS D 239
ASN D 601
VAL D 604
ALA D 242
1.25A17.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE C 702
PHE C 888
LEU C1031
LEU C 898
1.09A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
ILE B 979
PHE B 741
LEU B 735
LEU B 986
ASP B 719
1.48A16.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
ILE C 687
PRO A 774
PHE A 779
LEU A 776
1.14A16.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6cs2 ACE2
(Homo
sapiens)		5 / 9
ILE D 256
PRO D 490
LEU D 266
LEU D 162
ASP D 157
1.75A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		6cs2 ACE2
(Homo
sapiens)		5 / 9
ILE D 256
PRO D 490
LEU D 266
LEU D 162
ASP D 157
1.75A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6cs2 ACE2
(Homo
sapiens)		4 / 7
HIS D 378
HIS D 374
VAL D 404
ALA D 403
1.52A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6cs2 ACE2
(Homo
sapiens)		4 / 7
HIS D 378
HIS D 374
VAL D 404
ALA D 403
1.51A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.48A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.53A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.53A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.47A22.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 8
ASP E 364
PHE E 338
LEU E 368
PHE E 515
1.20A20.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
ILE A 309
PHE A 279
LEU A  78
PHE A  74
0.93A21.01
3PH  A 708 ( 4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 9
ILE A  83
PHE A 279
LEU A  78
LEU A 281
PHE A 276
1.78A21.01
3PH  A 708 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6m1d ACE2
(Homo
sapiens)		4 / 7
HIS B 378
HIS B 374
VAL B 404
ALA B 403
1.55A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m1d ACE2
(Homo
sapiens)		4 / 8
ILE D 256
LEU D 248
TYR D 252
LEU D 267
1.20A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6m1d ACE2
(Homo
sapiens)		4 / 7
HIS B 378
HIS B 374
VAL B 404
ALA B 403
1.55A16.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  20
PHE A  66
LEU A  89
LEU A  87
VAL A  36
1.62A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL B  20
PHE B  66
LEU B  89
LEU B  87
VAL B  36
1.62A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL B 261
LEU B 205
LEU B 242
THR B 243
VAL B 202
1.58A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL D  20
PHE D  66
LEU D  89
LEU D  87
VAL D  36
1.64A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL D 261
LEU D 205
LEU D 242
THR D 243
VAL D 202
1.59A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL D  77
PHE D  66
LEU D  89
VAL D  91
VAL D  36
1.50A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL C 261
LEU C 205
LEU C 242
THR C 243
VAL C 202
1.57A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL C  20
PHE C  66
LEU C  89
LEU C  87
VAL C  36
1.60A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL B  77
PHE B  66
LEU B  89
VAL B  91
VAL B  36
1.47A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.58A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.56A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.35A20.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.54A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
THR D  89
THR D  93
1.67A14.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.48A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
NSP7
(SARS-CoV-2)		4 / 8
PHE A 843
LEU A 437
LEU C  40
PHE A 442
1.61A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.48A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 246
VAL A 182
1.38A14.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 286
LEU A 316
PHE A 317
1.30A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 741
LEU A 723
LEU A 707
THR A 710
VAL A 720
1.57A14.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.53A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 248
THR A 246
1.57A14.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
PRO A 627
PHE A 694
LEU A 786
LEU A 630
1.50A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.51A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		5 / 9
ILE A 201
PRO A 232
PHE A 192
LEU A  90
LEU A 205
1.79A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.52A14.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE B 119
PRO A 323
LEU A 270
PHE A 275
1.51A15.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE A 333
PRO A 339
LEU B  95
PHE B  92
1.56A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 837
PHE A 419
LEU A 883
PHE A 428
1.56A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 238
LEU A 316
PHE A 313
1.53A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
LEU D  95
THR D  93
1.58A14.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
ILE A 244
LEU A 247
TYR A 175
PHE A 134
1.46A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE B 979
PHE B 741
LEU B 735
LEU B 986
ASP B 719
1.33A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
ILE B 979
PHE B 741
LEU B 735
LEU B 986
1.05A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE A 787
PRO A1035
LEU A 788
LEU A 859
PHE A 870
1.76A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOD_A_HQEA1173_1
(FMN-BINDING PROTEIN)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		4 / 7
TYR L  37
HIS L  98
ASP L  33
HIS H 109
1.55A23.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.35A20.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6nur NSP12
(SARSr-CoV)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.54A14.94
 ZN  A1002 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6nus NSP12
(SARSr-CoV)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 246
VAL A 182
1.35A13.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6nus NSP12
(SARSr-CoV)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.56A14.94
 ZN  A1002 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
ILE A 434
PRO A 384
LEU A 368
LEU A 387
PHE A 515
1.78A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASP C 979
PHE B 565
LEU B 546
LEU B 518
1.19A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
ILE A 434
PRO A 384
LEU A 368
LEU A 387
PHE A 515
1.79A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		6 / 10
GLN B 118
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		6 / 10
GLN A 118
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6vxs NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE C 666
PRO A 862
LEU C 611
LEU A 861
1.22A15.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE C 666
PRO A 862
LEU C 611
LEU A 861
1.20A15.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w02 NSP3
(SARS-CoV-2)		6 / 10
GLN B 118
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.63A23.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
PRO C 384
LEU C 513
LEU C 387
PHE C 392
1.70A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 358
PHE C 342
TYR C 365
LEU C 513
1.77A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
PHE C 515
LEU C 387
LEU C 513
PHE C 338
1.37A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 10
VAL L  27
PHE L  71
LEU L  33
LEU L   4
THR L  97
1.78A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 434
PRO C 384
LEU C 368
LEU C 387
1.57A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
LEU A6959
LEU A6981
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 10
GLN B 118
LEU B  93
LEU B 122
THR B 149
VAL B  36
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.70A
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.71A
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.68A
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.67A
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B  93
LEU B 127
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B 127
LEU B 153
1.73A16.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL A  95
LEU A  93
VAL A  36
THR A 149
VAL A  34
1.79A24.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 10
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		6 / 10
GLN A 118
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
LEU A6959
LEU A6981
1.39A15.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
LEU C6959
LEU C6981
1.41A15.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  60
VAL B  11
ALA B  68
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  15
VAL B  66
ALA B  68
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS C  17
ASN C  60
VAL C  11
ALA C  68
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  15
VAL B  66
ALA B  68
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  60
VAL B  11
ALA B  68
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  15
VAL B  66
ALA B  68
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS B  17
ASN B  60
VAL B  11
ALA B  68
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
HIS C  17
ASN C  60
VAL C  11
ALA C  68
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.68A
None
None
None
MES  A 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
None
None
MES  A 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
None
None
MES  A 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wcf NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		6 / 10
GLN A 118
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
PRO A 136
LEU A 109
TYR A 113
LEU A 126
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wen NSP3
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 298
ASN A 241
ALA A 293
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 249
ASN A 241
HIS A 298
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		6 / 10
GLN A 322
LEU A 297
VAL A 299
LEU A 326
THR A 353
VAL A 240
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 298
ASN A 241
ALA A 293
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 249
ASN A 241
HIS A 298
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 298
HIS A 249
ASN A 258
ALA A 242
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 298
HIS A 249
ASN A 258
ALA A 242
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 298
ASN A 241
ALA A 293
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 298
HIS A 249
ASN A 258
ALA A 242
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
PRO A 329
PHE A 320
LEU A 297
LEU A 331
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wey NSP3
(SARS-CoV-2)		4 / 7
HIS A 290
HIS A 249
ASN A 241
HIS A 298
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL A  12
LEU A  13
VAL A  16
LEU B  95
THR B  93
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE E 351
PHE E 346
LEU E 339
PHE E 307
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE C 351
PHE C 346
LEU C 339
PHE C 307
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE B 351
PHE B 346
LEU B 339
PHE B 307
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE F 351
PHE F 346
LEU F 339
PHE F 307
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE D 351
PHE D 346
LEU D 339
PHE D 307
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE A 351
PHE A 346
LEU A 339
PHE A 307
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
HIS A6917
HIS C6917
VAL C7087
ALA C6919
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 5
HIS A6917
HIS C6917
VAL C7087
ALA C6919
1.53A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
HIS A6917
HIS C6917
VAL C7087
ALA C6919
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
LEU A6959
LEU A6981
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
HIS A6917
HIS C6917
VAL C7087
ALA C6919
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
LEU C6959
LEU C6981
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO A 168
PHE A  66
LEU A  56
LEU A 167
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO D 168
PHE D  66
LEU D  56
LEU D 167
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO B 168
PHE B  66
LEU B  56
LEU B 167
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO C 168
PHE C  66
LEU C  56
LEU C 167
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6925
PHE C6985
LEU C6959
LEU C6981
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
LEU A6959
LEU A6981
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO B  68
LEU B  76
TYR B 325
PHE B 195
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A 223
LEU A 228
LEU A 300
PHE A 303
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B 223
LEU B 228
LEU B 300
PHE B 303
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO A  68
LEU A  76
TYR A 325
PHE A 195
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.67A
None
None
None
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.65A
None
None
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO D 125
PHE D 116
LEU D  93
LEU D 127
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 10
GLN C 118
LEU C  93
VAL C  95
LEU C 122
THR C 149
VAL C  36
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 10
GLN A 118
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
None
None
APR  B 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 10
GLN B 118
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.67A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.68A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.64A
None
None
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.65A
None
None
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO C 125
PHE C 116
LEU C  93
LEU C 127
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.66A
None
None
None
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.66A
None
None
None
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
PHE A   6
LEU A 123
VAL A  34
THR A 149
VAL A  36
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B  93
LEU B 127
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
PHE C   6
LEU C 123
VAL C  34
THR C 149
VAL C  36
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
PHE D   6
LEU D 123
VAL D  34
THR D 149
VAL D  36
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.68A
None
None
None
APR  B 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.69A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
None
None
APR  B 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6925
PHE A6985
LEU A6959
LEU A6981
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE A  68
PHE B  92
LEU A  71
LEU A  59
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
LEU D  95
THR D  93
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL A  12
LEU A  13
VAL A  16
LEU B  95
THR B  93
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
GLN B  88
VAL A  16
VAL A  12
LEU C  40
VAL C  11
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE B 106
PHE B  92
LEU A  56
LEU A  71
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
ILE D 106
PHE D  92
LEU C  56
LEU C  71
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
HIS A  17
ASN A  60
VAL A  11
ALA A  68
1.48A
 CL  A 506 ( 4.7A)
None
CL  A 506 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
HIS A  17
ASN A  60
VAL A  11
ALA A  68
1.42A
 CL  A 506 ( 4.7A)
None
CL  A 506 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
HIS A  17
ASN A  60
VAL A  11
ALA A  68
1.47A
 CL  A 506 ( 4.7A)
None
CL  A 506 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6xez NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.32A21.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.53A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
LEU A  30
VAL A  18
LEU A  32
THR A  98
VAL A  36
1.77A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A  74
LEU A  89
VAL A  91
VAL A  36
TRP A  31
1.70A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 106
PHE B  92
LEU A  60
LEU A  71
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 10
VAL A  12
LEU A  13
VAL A  16
LEU B  95
THR B  93
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE A  68
PHE B  92
LEU A  71
LEU A  60
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 10
GLN B  88
VAL A  16
VAL A  12
LEU C  40
VAL C  11
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE D 106
PHE D  92
LEU C  56
LEU C  71
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
ILE B 106
PHE B  92
LEU A  56
LEU A  71
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
LEU D  95
THR D  93
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 515
LEU E 387
LEU E 513
PHE E 338
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PRO E 384
LEU E 513
LEU E 387
PHE E 392
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 434
PRO E 384
LEU E 368
LEU E 387
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 515
LEU A 387
LEU A 513
PHE A 338
1.33A
None
DMS  A 905 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE A 434
PRO A 384
LEU A 368
LEU A 387
1.49A
None
None
None
DMS  A 905 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 434
PRO E 384
LEU E 368
LEU E 387
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 515
LEU E 387
LEU E 513
PHE E 338
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PRO E 384
LEU E 513
LEU E 387
PHE E 392
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PRO E 384
LEU E 513
LEU E 387
PHE E 392
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 515
LEU E 387
LEU E 513
PHE E 338
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 434
PRO E 384
LEU E 368
LEU E 387
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE A 434
PRO A 384
LEU A 368
LEU A 387
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PRO A 384
LEU A 513
LEU A 387
PHE A 392
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 515
LEU A 387
LEU A 513
PHE A 338
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A  74
LEU A  89
VAL A  91
VAL A  36
TRP A  31
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.51A
None
None
None
None
PEG  A 405 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
None
None
EDO  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.69A
None
None
None
EPE  E 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.41A
None
None
None
EDO  A 202 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B  93
LEU B 127
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.62A
None
None
None
EDO  A 203 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.70A
None
None
None
EDO  D 205 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU E  93
VAL E  95
LEU E 122
THR E 149
VAL E  36
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.71A
None
None
None
EPE  E 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
PHE D   6
LEU D 123
VAL D  34
THR D 149
VAL D  36
1.71A
None
None
None
EDO  D 203 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU C  93
VAL C  95
LEU C 122
THR C 149
VAL C  36
1.59A
None
None
None
EDO  C 206 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.70A
None
None
None
EPE  E 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN B 118
LEU B  93
LEU B 122
THR B 149
VAL B  36
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU D  93
VAL D  95
LEU D 122
THR D 149
VAL D  36
1.60A
None
None
None
EDO  D 203 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.71A
None
None
None
EDO  D 205 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN C 118
LEU C  93
LEU C 122
THR C 149
VAL C  36
1.63A
None
None
None
EDO  C 206 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO C 125
PHE C 116
LEU C  93
LEU C 127
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN D 118
LEU D  93
LEU D 122
THR D 149
VAL D  36
1.64A
EDO  D 201 ( 4.4A)
None
None
EDO  D 203 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN A 118
LEU A  93
LEU A 122
THR A 149
VAL A  36
1.63A
EDO  D 201 ( 4.5A)
None
None
EDO  A 203 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO D 136
LEU D 109
TYR D 113
LEU D 126
1.61A
None
EDO  D 204 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.70A
None
None
None
EDO  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO D 125
PHE D 116
LEU D  93
LEU D 127
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.69A
None
None
None
EDO  D 205 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.71A
None
None
None
EDO  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN E 118
LEU E  93
LEU E 122
THR E 149
VAL E  36
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO E 125
PHE E 116
LEU E  93
LEU E 127
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.70A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO E 125
PHE E 116
LEU E  93
LEU E 127
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
None
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.70A
None
None
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.69A
None
None
None
APR  E 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO D 136
LEU D 109
TYR D 113
LEU D 126
1.62A
None
None
None
APR  D 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU D  93
VAL D  95
LEU D 122
THR D 149
VAL D  36
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.70A
None
None
None
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO D 125
PHE D 116
LEU D  93
LEU D 127
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
None
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
None
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  45
ASN D  37
HIS D  94
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.68A
None
None
None
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  86
HIS D  94
ASN D  37
ALA D  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.69A
None
None
None
APR  E 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B  93
LEU B 127
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU C  93
VAL C  95
LEU C 122
THR C 149
VAL C  36
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN A 118
LEU A  93
LEU A 122
THR A 149
VAL A  36
1.60A
EDO  D 203 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.68A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  94
HIS E  45
ASN E  54
ALA E  38
1.70A
None
None
None
APR  E 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN E 118
LEU E  93
LEU E 122
THR E 149
VAL E  36
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.71A
None
None
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN D 118
LEU D  93
LEU D 122
THR D 149
VAL D  36
1.59A
EDO  A 207 ( 4.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO C 125
PHE C 116
LEU C  93
LEU C 127
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  45
ASN E  37
HIS E  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS E  86
HIS E  94
ASN E  37
ALA E  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 10
GLN B 118
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.69A
None
None
None
APR  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS D  94
HIS D  45
ASN D  54
ALA D  38
1.69A
None
None
None
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.70A
None
None
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN C 118
LEU C  93
LEU C 122
THR C 149
VAL C  36
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU E  93
VAL E  95
LEU E 122
THR E 149
VAL E  36
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.68A
None
None
None
MES  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.69A
None
None
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  59
HIS A  86
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  59
HIS A  86
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.69A
None
None
None
MES  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  59
HIS A  86
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.70A
None
None
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU C  93
VAL C  95
LEU C 122
THR C 149
VAL C  36
1.61A
None
None
None
EDO  C 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  45
ASN B  37
HIS B  94
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO C 125
PHE C 116
LEU C  93
LEU C 127
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO B 125
PHE B 116
LEU B  93
LEU B 127
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  45
ASN A  37
HIS A  94
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  94
HIS C  45
ASN C  54
ALA C  38
1.70A
None
None
None
MES  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  45
ASN C  37
HIS C  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  86
HIS A  94
ASN A  37
ALA A  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 10
GLN B 118
LEU B  93
VAL B  95
LEU B 122
THR B 149
VAL B  36
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  86
HIS B  94
ASN B  37
ALA B  89
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
LEU A  93
VAL A  95
LEU A 122
THR A 149
VAL A  36
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS A  94
HIS A  45
ASN A  54
ALA A  38
1.68A
None
None
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN A 118
LEU A  93
LEU A 122
THR A 149
VAL A  36
1.63A
EDO  A 202 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS B  94
HIS B  45
ASN B  54
ALA B  38
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO B 136
LEU B 109
TYR B 113
LEU B 126
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
PRO A 125
PHE A 116
LEU A  93
LEU A 127
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
HIS C  86
HIS C  94
ASN C  37
ALA C  89
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
GLN C 118
LEU C  93
LEU C 122
THR C 149
VAL C  36
1.62A
EDO  A 204 (-4.1A)
None
None
EDO  C 204 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 837
PHE A 419
LEU A 838
LEU A 883
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.64A
 ZN  A1002 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
LEU D  95
THR D  93
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE B 119
PRO A 323
LEU A 270
PHE A 275
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 286
LEU A 316
PHE A 317
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A  66
PHE A  70
TYR A  69
LEU A  19
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE A 539
PRO A 328
LEU A 673
LEU B 117
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL A 330
LEU B 117
VAL B 115
THR B 123
THR B 124
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
PRO A 627
PHE A 694
LEU A 786
LEU A 630
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 10
PHE A 741
LEU A 723
LEU A 707
THR A 710
VAL A 720
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE A 333
PRO A 339
LEU B  95
PHE B  92
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.63A
 ZN  A1002 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		5 / 9
ILE A 201
PRO A 232
PHE A 192
LEU A 205
ASP A 218
1.74A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 238
LEU A 316
PHE A 313
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 246
VAL A 182
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7btf NSP8
(SARS-CoV-2)		5 / 10
VAL D 167
LEU D 184
VAL D 159
THR D 145
VAL D 186
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		5 / 9
ILE A 201
PRO A 232
PHE A 192
LEU A 205
ASP A 218
1.72A19.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.63A
 ZN  A1002 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
ILE A 244
LEU A 247
TYR A 175
PHE A 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7btf NSP12
(SARS-CoV-2)		5 / 8
ILE A 201
PRO A 232
PHE A 192
LEU A  90
LEU A 205
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A 261
LEU A 205
LEU A 242
THR A 243
VAL A 202
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  77
PHE A  66
LEU A  89
VAL A  91
VAL A  36
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  20
PHE A  66
LEU A  89
LEU A  87
VAL A  36
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE A 333
PRO A 339
LEU B  95
PHE B  92
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_B_HQEB503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
ILE A 201
PRO A 232
PHE A 192
LEU A  90
LEU A 205
1.76A19.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_A_HQEA503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
ILE A 201
PRO A 232
PHE A 192
LEU A  90
LEU A 205
1.74A19.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.63A
 ZN  A1002 (-3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.61A
 ZN  A1002 (-3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.61A
 ZN  A1002 (-3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL C  12
LEU C  13
VAL C  16
LEU D  95
THR D  93
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 741
LEU A 723
LEU A 707
THR A 710
VAL A 720
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL A 330
LEU B 117
VAL B 115
THR B 123
THR B 124
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ILE A 539
PRO A 328
LEU A 673
LEU B 117
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
PRO A 627
PHE A 694
LEU A 786
LEU A 630
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 8
ILE A 201
PRO A 232
PHE A 192
LEU A  90
LEU A 205
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ASP A 833
PRO A 832
LEU A 838
LEU A 869
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 286
LEU A 316
PHE A 317
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 246
VAL A 182
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 248
THR A 246
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
ILE A 244
LEU A 247
TYR A 175
PHE A 134
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 238
LEU A 316
PHE A 313
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
ASP A 336
PHE A 340
LEU A 366
PHE B  92
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 244
LEU A 247
TYR A 175
PHE A 134
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.56A
 ZN  A1002 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
NSP7
(SARS-CoV-2)		4 / 8
PHE A 843
LEU A 437
LEU C  40
PHE A 442
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 741
LEU A 723
LEU A 707
THR A 710
VAL A 720
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 248
THR A 246
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
LEU A 186
TYR A 238
LEU A 316
PHE A 313
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL A 330
LEU B 117
VAL B 115
THR B 123
THR B 124
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 201
PRO A 232
LEU A  90
LEU A 205
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ILE A 837
PHE A 419
LEU A 883
PHE A 428
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 287
LEU A 186
LEU A 245
THR A 246
VAL A 182
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
VAL A 330
LEU B 103
THR B 124
VAL A 341
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PRO A 627
PHE A 694
LEU A 786
LEU A 630
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.54A
 ZN  A1002 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
HIS A 642
ASN A 568
HIS A 572
ALA A 639
1.54A
 ZN  A1002 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
HIS A  99
ASN A 209
VAL A  96
ALA A  97
1.70A
None