Ligand ID: 30B


Drugbank ID:
DB06290
(Simeprevir)


Indication:
Indicated for the treatment of adults with chronic hepatitis C virus (HCV) infection: typically in combination with sofosbuvir in patients with HCV genotype 1 without cirrhosis or with compensated cirrhosis and in combination with peginterferon alfa (Peg-IFN-alfa) and ribavirin (RBV) in patients with HCV genotype 1 or 4 without cirrhosis or with compensated cirrhosis.

Get human targets for 30B in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '30B'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.58A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.20A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.53A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		1x7q BETA-2-MICROGLOBULIN
HLA, A-11
(Homo
sapiens)		3 / 3
PHE B  56
TYR A   9
LEU B  65
1.31A17.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		1z1i 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.26A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		1z1i 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.25A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		1z1i 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.23A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B1138
GLY B1170
ARG B1131
ALA B1194
ASP B1197
1.51A22.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
GLY B 120
GLY B 146
PHE B 140
ALA B 116
CYH B 128
1.59A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2ajf ACE2
(Homo
sapiens)		3 / 3
PHE B 356
TYR B 381
LEU B 359
1.08A15.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.56A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.25A22.73
CY6  A1145 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.28A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
GLY H 296
GLY G 317
PHE G 316
ALA H 306
ALA H 309
1.35A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
GLY B 296
GLY A 317
PHE A 316
ALA B 306
ALA B 309
1.29A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 120
GLY B 146
PHE B 140
ALA B 116
CYH B 128
1.59A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
HIS H 164
SER L 138
PHE L 140
ALA L 175
ALA L 176
1.56A23.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
HIS H 164
SER L 138
PHE L 140
ALA L 175
ALA L 176
1.49A23.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2dd8 SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE S 501
TYR S 367
LEU S 504
1.19A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
GLY S 490
VAL H  37
GLY H  50
ALA H  93
ASP H 101
1.25A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		2fxp SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A  15
VAL C   8
GLY C  11
SER C  14
ASP B  12
1.45A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
HIS A  70
GLY A  71
ALA A  65
ALA A  65
ASP A  64
1.20A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
HIS A   2
GLY A   1
ALA A  65
ALA A  65
ASP A  64
1.35A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
GLY A  71
ARG A  62
ALA A  65
ALA A  65
ASP A  64
1.05A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
HIS A  70
GLY A  71
ARG A  62
ALA A  65
ASP A  64
1.13A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
GLY A  71
SER A  67
ALA A  65
ALA A  65
ASP A  64
1.16A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
HIS A   2
GLY A   1
GLY A  71
SER A  67
ARG A 113
1.35A22.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 12
GLN D 170
GLY D  42
ARG D  38
ALA D  92
ASP D  90
1.51A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.24A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_2
(GENOME POLYPROTEIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 4
GLN A   0
PHE A  15
TYR A   7
VAL A  51
1.52A19.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
GLY B 296
GLY A 317
PHE A 316
ALA B 306
ALA B 309
1.35A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
GLY B 296
GLY A 317
PHE A 316
ALA B 306
ALA B 309
1.33A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2kaf NSP3
(SARSr-CoV)		3 / 3
PHE A  50
TYR A  16
LEU A  28
1.40A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2kqw NSP3
(SARSr-CoV)		3 / 3
PHE A 181
TYR A 147
LEU A 159
1.33A20.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.31A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
GLY B 120
GLY B 146
PHE B 140
ALA B 116
CYH B 128
1.58A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 4
PHE D 329
TYR D 193
VAL B 275
LEU B 248
1.42A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
PHE B 240
TYR B 237
LEU B 245
1.41A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
GLN D   6
GLY B 174
PHE B 185
ALA B 193
ALA B 194
1.43A6.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2qc2 3C-LIKE PROTEINASE
(-)		3 / 3
PHE A 291
TYR B 126
LEU A 287
1.33A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
PHE A   3
TYR A 126
LEU A 287
1.37A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.29A23.10
CYV  A 302 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
PHE A 341
TYR A 230
LEU A 248
1.37A20.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
GLY A  81
GLY A  71
ARG A  86
ALA A 107
ASP A 108
1.49A21.69
SFG  A1298 (-3.5A)
SFG  A1298 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.26A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.30A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.28A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
SARSr-CoV)		5 / 12
GLN B  99
GLY A 488
LYS A 390
GLY A 391
PHE A 483
1.35A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE F 387
TYR F 494
LEU F 478
1.36A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
PHE A 356
TYR A 381
LEU A 359
1.15A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE F 387
TYR F 494
LEU F 478
1.37A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_2
(GENOME POLYPROTEIN)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 4
GLN A  76
PHE A  32
TYR E 442
LEU A  85
1.75A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_2
(GENOME POLYPROTEIN)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 4
GLN B  37
PHE B 390
TYR B 385
VAL F 404
1.79A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.62A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.44A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.29A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.37A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.35A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
HIS B 172
GLY B 170
GLY A   2
SER A   1
ALA B 116
1.39A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.36A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.46A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3i6k HLA, A-2
(Homo
sapiens)		5 / 12
ASP E  39
LYS E  68
PHE E  22
ARG E  21
ALA E  24
1.51A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
PHE A 291
TYR B 126
LEU A 287
1.36A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 120
GLY B 146
PHE B 140
ALA B 116
CYH B 128
1.62A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
PHE A   3
TYR A 126
LEU A 287
1.35A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
SER A   1
ARG B 131
ASP B 197
1.29A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
SER A   1
ARG B 131
ALA B 194
ASP B 197
1.29A22.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
GLY A  81
GLY A  71
ARG A  86
ALA A 107
ASP A 108
1.45A19.94
SAM  A 302 (-3.4A)
SAM  A 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
GLY A  81
GLY A  71
ARG A  86
ALA A 107
ASP A 108
1.46A19.94
SAM  A 302 (-3.4A)
SAM  A 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
GLY A  81
GLY A  71
ARG A  86
ALA A 107
ASP A 108
1.45A19.94
SAM  A 302 (-3.4A)
SAM  A 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3sci ACE2
(Homo
sapiens)		3 / 3
PHE A 356
TYR A 381
LEU A 359
1.14A14.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLN B 325
GLY B 326
GLY F 488
ALA B 386
ASP B 382
1.53A13.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
PHE A 356
TYR A 381
LEU A 359
1.10A13.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.40A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.47A23.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
HIS A 172
GLY A 170
GLY B   2
SER B   1
ALA A 116
1.62A23.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.49A23.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		5 / 12
HIS B 192
VAL B 188
GLY B 194
ARG B 229
ALA B 231
1.54A21.05
 ZN  B 901 ( 4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.30A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.37A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY B 138
GLY B 170
ARG B 131
ALA B 194
ASP B 197
1.40A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5c5o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.27A22.73
SDJ  B 401 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
PHE D 240
TYR D 237
LEU D 177
1.07A17.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
PHE D 240
TYR D 237
LEU D 177
1.03A17.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
HIS C  80
ASP D 126
ARG D  53
ALA C   4
ASP D  10
1.49A25.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
HIS C  80
ASP D 126
ARG D  53
ALA C   4
ASP D  10
1.43A25.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
PHE B 240
TYR B 237
LEU B 177
1.07A17.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
HIS N  80
ASP B 126
ARG B  53
ALA N   4
ASP B  10
1.41A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
HIS N  80
ASP B 126
ARG B  53
ALA N   4
ASP B  10
1.47A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
VAL C   4
GLY C  59
SER C  56
ALA P   4
ASP C  10
1.41A17.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5r82 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.23A23.55
DMS  A1005 ( 3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.66A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.68A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.66A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.75A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.34A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.72A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A1041
ASP A 849
VAL A 860
ALA A 853
ALA A 857
1.31A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A1041
ASP A 849
VAL A 860
ALA A 853
ALA A 857
1.29A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE A 231
TYR A  88
LEU A 224
1.44A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		3 / 3
PHE A 501
TYR A 367
LEU A 504
1.27A9.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
ASP B 771
GLY C 953
SER C 858
ALA C 969
ALA C 968
1.36A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
ASP B 771
GLY C 953
SER C 858
ALA C 969
ALA C 968
1.36A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
ASP B 771
GLY C 953
SER C 858
ALA C 969
ALA C 968
1.37A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
GLY C1041
ASP C 849
VAL C 860
ALA C 853
ALA C 857
1.27A9.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
GLY B 512
ASP B 376
ALA B 371
CYH B 366
ASP C 967
1.52A9.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
GLY C1041
ASP C 849
VAL C 860
ALA C 853
ALA C 857
1.25A9.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5x5c S PROTEIN
(MERS-CoV)		3 / 3
PHE C 254
TYR C 243
LEU C 251
1.42A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		5x5f S PROTEIN
(MERS-CoV)		6 / 12
GLY C 864
VAL C 958
GLY C 953
SER C 859
ALA C 969
ALA C 968
1.70A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		5x5f S PROTEIN
(MERS-CoV)		4 / 4
PHE A 323
TYR A  71
VAL A 356
LEU A 347
1.62A9.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A  39
GLY A 199
PHE A 185
ALA A  90
ALA A  91
1.36A10.14
GLY  A  39 ( 0.0A)
GLY  A 199 ( 0.0A)
PHE  A 185 ( 1.3A)
ALA  A  90 ( 0.0A)
ALA  A  91 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY A  39
GLY A 199
PHE A 185
ALA A  90
ALA A  91
1.36A10.14
GLY  A  39 ( 0.0A)
GLY  A 199 ( 0.0A)
PHE  A 185 ( 1.3A)
ALA  A  90 ( 0.0A)
ALA  A  91 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE C 185
TYR C 200
LEU C 257
1.35A10.14
PHE  C 185 ( 1.3A)
TYR  C 200 ( 1.3A)
LEU  C 257 ( 0.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY B1041
ARG B 797
ALA B 853
ALA B 854
ASP B 850
1.42A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY B1041
ARG B 797
ALA B 853
ALA B 854
ASP B 850
1.38A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLY B1041
ARG B 797
ALA B 853
ALA B 854
ASP B 850
1.37A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE A 187
TYR A 252
LEU A  58
1.25A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY A  39
GLY A 199
PHE A 185
ALA A  90
ALA A  91
1.25A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY A  39
GLY A 199
PHE A 185
ALA A  90
ALA A  91
1.26A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
PHE B 379
TYR B 383
LEU B 374
1.15A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY C1041
ASP C 849
VAL C 860
ALA C 853
ALA C 857
1.23A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6cs2 ACE2
(Homo
sapiens)		3 / 3
PHE D 356
TYR D 381
LEU D 359
0.87A13.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY C1041
ASP C 849
VAL C 860
ALA C 853
ALA C 857
1.25A9.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.74A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.55A22.30
ICB  D   1 ( 3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN B 498
GLY B 496
GLY A 352
PHE A 390
ALA A  36
1.43A24.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		3 / 3
PHE E 515
TYR E 380
LEU E 518
1.18A24.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.74A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.51A23.55
DMS  A 402 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m17 ACE2
(Homo
sapiens)		3 / 3
PHE D 356
TYR D 381
LEU D 359
1.14A11.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
GLY A 438
GLY A 115
SER A 118
ALA A 282
ALA A 498
1.36A14.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
VAL C 207
GLY C 428
SER C 430
PHE C 433
ALA C 222
1.32A14.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m18 ACE2
(Homo
sapiens)		5 / 12
HIS B 417
ASP B 543
VAL B 293
GLY B 422
SER B 420
1.44A11.30
NAG  B 910 ( 4.6A)
NAG  B 910 ( 4.9A)
None
None
NAG  B 910 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
VAL C 207
GLY C 428
SER C 430
PHE C 433
ALA C 222
1.30A14.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
GLY A 438
GLY A 115
SER A 118
ALA A 282
ALA A 498
1.35A14.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
PHE D   3
TYR B 126
LEU D 286
1.35A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
PHE C 219
TYR C 209
LEU C 286
1.76A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY C 120
GLY C 146
PHE C 140
ALA C 116
CYH C 128
1.66A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN B 189
VAL B 171
PHE B 185
ALA B 193
ALA B 194
1.49A23.55
3WL  B 401 (-4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
PHE A   3
TYR C 126
LEU A 286
1.34A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.68A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
PHE D 219
TYR D 209
LEU D 286
1.71A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY D 120
GLY D 146
PHE D 140
ALA D 116
CYH D 128
1.66A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY B 120
GLY B 146
PHE B 140
ALA B 116
CYH B 128
1.68A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
PHE C   3
TYR A 126
LEU C 286
1.40A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.29A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.76A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.65A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.33A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.64A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.33A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.65A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.72A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 258
VAL A 296
ALA A 211
ALA A 210
ASP A 216
1.73A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
PHE A 192
TYR A  87
LEU A 187
1.44A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ASP A 477
GLY A 485
ARG A 640
ALA A 639
ASP A 304
1.57A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 708
0.92A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.67A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 205
1.39A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 129
LEU A 205
1.50A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.66A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
PHE A 313
TYR A 286
LEU A 351
1.51A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
GLY A 345
VAL A 398
GLY A 327
ALA A 379
ALA A 382
1.78A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.77A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 4
PHE A  35
TYR A 129
VAL A 233
LEU A 205
1.60A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
GLY A 345
VAL A 398
GLY A 327
ALA A 379
ALA A 382
1.77A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ASP A 477
GLY A 485
ARG A 640
ALA A 639
ASP A 304
1.62A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 4
PHE A  45
TYR A 788
VAL A 233
LEU A 205
1.59A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.76A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_2
(GENOME POLYPROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
GLN C 769
PHE C 870
TYR C 855
VAL A1050
1.67A10.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		3 / 3
PHE H  59
TYR H 106
LEU H  48
1.25A24.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6nur NSP12
(SARSr-CoV)		4 / 4
PHE A 326
TYR A 273
VAL A 662
LEU A 663
1.75A11.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
PHE B 194
TYR B 265
LEU B  54
1.32A9.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
PHE C  92
TYR C 269
VAL C 227
LEU C 226
1.65A9.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6vw1 ACE2
(Homo
sapiens)		5 / 12
HIS A 417
ASP A 543
VAL A 293
GLY A 422
SER A 420
1.49A15.24
None
None
None
None
NAG  A 707 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6vw1 ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN B 325
GLY B 326
GLY F 502
ALA B 386
ASP B 382
1.45A15.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
PHE E 515
TYR E 380
LEU E 518
1.37A21.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
PHE B 123
TYR B 180
LEU B 120
1.20A20.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
PHE B  92
TYR B 269
VAL B 227
LEU B 226
1.56A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
PHE C  92
TYR C 269
LEU C 226
1.41A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
PHE C 194
TYR C 265
LEU C  54
1.29A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
PHE B  92
TYR B 269
VAL B 227
LEU B 226
1.56A9.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
PHE L  71
TYR L  92
LEU L  47
0.80A20.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
GLN C 409
GLY C 416
ARG C 457
ALA C 352
ASP C 467
1.60A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
PHE C 515
TYR C 380
LEU C 518
1.22A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
PHE H 166
TYR L 173
LEU H 170
1.39A20.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.50A21.88
SAM  A7102 (-3.4A)
SAM  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.46A21.88
SAM  A7102 (-3.4A)
SAM  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w4h NSP16
(SARS-CoV-2)		3 / 3
PHE A7048
TYR A6845
LEU A7052
1.38A21.88
None
SAM  A7102 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.51A21.88
SAM  A7102 (-3.4A)
SAM  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
PHE A7048
TYR A6845
LEU A7052
1.39A
None
SAM  A7104 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.49A
SAM  A7104 (-3.6A)
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.73A
None
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.76A
None
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.54A
SAM  A7104 (-3.6A)
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.53A
SAM  A7104 (-3.6A)
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
HIS B4336
GLY B4341
VAL B4361
ALA B4324
ASP A6904
1.66A
 ZN  B4403 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
PHE A 219
TYR A 209
LEU A 286
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.37A
X77  A 401 ( 3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.66A
None
None
MES  B 201 ( 4.5A)
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.61A
None
None
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.67A
None
None
MES  B 201 ( 4.5A)
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.78A
None
None
None
AMP  A 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.70A
None
None
None
AMP  A 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.60A
None
None
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.43A22.55
SAM  C7105 ( 3.4A)
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.75A22.55
 NA  C7104 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.76A22.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A22.55
None
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP A6928
GLY A6875
SER A6872
PHE A6901
ALA A6870
1.80A22.55
SAM  A7102 ( 3.7A)
None
SAM  A7102 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS B4336
GLY B4341
VAL B4361
ALA B4324
ASP A6904
1.59A21.35
 ZN  B4401 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.49A22.55
SAM  C7105 ( 3.4A)
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP C6928
GLY C6875
SER C6872
PHE C6901
ALA C6870
1.78A22.55
SAM  C7105 ( 3.7A)
None
SAM  C7105 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.73A22.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.69A22.55
None
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.50A22.55
SAM  A7102 ( 3.4A)
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
PHE C7048
TYR C6845
LEU C7052
1.40A22.55
None
SAM  C7105 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.72A22.55
None
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP C6928
GLY C6875
SER C6872
PHE C6901
ALA C6870
1.76A22.55
SAM  C7105 ( 3.7A)
None
SAM  C7105 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.44A22.55
SAM  A7102 ( 3.4A)
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.72A22.55
 NA  C7104 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP A6928
GLY A6875
SER A6872
PHE A6901
ALA A6870
1.78A22.55
SAM  A7102 ( 3.7A)
None
SAM  A7102 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.49A22.55
SAM  A7102 ( 3.4A)
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS D4333
ASP C6900
VAL D4295
ALA C6877
ASP C6897
1.79A21.35
None
None
None
None
SAM  C7105 ( 2.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP C6928
GLY C6875
SER C6872
PHE C6901
ALA C6870
1.75A22.55
SAM  C7105 ( 3.7A)
None
SAM  C7105 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ASP D4317
VAL D4369
GLY D4378
PHE D4363
ALA D4307
1.72A21.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.68A22.55
None
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS D4336
GLY D4341
VAL D4361
ALA D4324
ASP C6904
1.61A21.35
 ZN  D4401 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
PHE A7048
TYR A6845
LEU A7052
1.38A22.55
None
SAM  A7102 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A22.55
None
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASP C6928
GLY C6875
SER C6872
PHE C6901
ALA C6870
1.78A22.55
SAM  C7105 ( 3.7A)
None
SAM  C7105 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.48A22.55
SAM  C7105 ( 3.4A)
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.73A22.55
None
SAM  C7105 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY B  38
GLY B  81
SER B  85
ALA B 149
ALA B 153
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY C  38
GLY C  81
SER C  85
ALA C 149
ALA C 153
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
PHE A 241
TYR A 213
LEU A 118
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
PHE B 241
TYR B 213
LEU B 118
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY B  38
GLY B  81
SER B  85
ALA B 149
ALA B 153
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A  38
GLY A  81
SER A  85
ALA A 149
ALA A 153
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
PHE C 241
TYR C 213
LEU C 118
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.71A
None
None
MES  A 201 (-4.4A)
MES  A 201 (-3.6A)
MES  A 201 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.72A
None
None
MES  A 201 (-4.4A)
MES  A 201 (-3.6A)
MES  A 201 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
GLY A 337
VAL A 245
SER A 332
ALA A 242
ALA A 243
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
GLY A 337
VAL A 245
SER A 332
ALA A 242
ALA A 243
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY C 316
GLY D 295
SER C 312
ALA D 305
ALA B 267
1.71A
None
None
None
CL  D 401 ( 4.6A)
CL  D 401 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY C 316
GLY D 295
SER C 312
ALA D 305
ALA B 267
1.72A
None
None
None
CL  D 401 ( 4.6A)
CL  D 401 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY E 295
GLY F 316
PHE F 315
ALA E 305
ALA E 308
1.21A
None
None
None
CL  E 401 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY C 316
GLY D 295
SER C 312
ALA D 305
ALA B 267
1.69A
None
None
None
CL  D 401 ( 4.6A)
CL  D 401 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY D 275
GLY D 278
PHE D 363
ALA D 359
ASP D 288
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY C 316
GLY D 295
SER C 312
ALA D 305
ALA B 267
1.70A
None
None
None
CL  D 401 ( 4.6A)
CL  D 401 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY D 295
GLY C 316
PHE C 315
ALA D 305
ALA D 308
1.27A
None
None
None
CL  D 401 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY B 275
GLY B 278
PHE B 363
ALA B 359
ASP B 288
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLY E 275
GLY E 278
PHE E 363
ALA E 359
ASP E 288
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.78A
FMT  C7107 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.68A
None
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A
None
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.75A
FMT  C7107 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.48A
SAH  A7102 (-3.5A)
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.53A
SAH  A7102 (-3.5A)
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
HIS D4333
ASP C6900
VAL D4295
ALA C6877
ASP C6897
1.77A
None
None
None
None
SAH  C7102 (-2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.69A
None
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.53A
SAH  A7102 (-3.5A)
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.73A
None
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
PHE A7048
TYR A6845
LEU A7052
1.39A
None
SAH  A7102 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.51A
SAH  C7102 (-3.5A)
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
HIS D4336
GLY D4341
VAL D4361
ALA D4324
ASP C6904
1.62A
 ZN  D4401 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.72A
None
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
HIS B4336
GLY B4341
VAL B4361
ALA B4324
ASP A6904
1.59A
 ZN  B4401 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.47A
SAH  C7102 (-3.5A)
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A
None
SAH  A7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
PHE C7048
TYR C6845
LEU C7052
1.41A
None
SAH  C7102 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.51A
SAH  C7102 (-3.5A)
SAH  C7102 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.73A
None
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.69A
None
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.74A
 NA  C7102 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.49A
SFG  C7103 ( 3.5A)
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP10
(SARS-CoV-2)		5 / 12
ASP D4317
VAL D4369
GLY D4378
PHE D4363
ALA D4307
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS D4336
GLY D4341
VAL D4361
ALA D4324
ASP C6904
1.61A
 ZN  D4401 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.54A
SFG  A7103 ( 3.5A)
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
GLY C6869
ASP C6895
ALA C6881
ASP C6904
1.72A
None
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
PHE A7048
TYR A6845
LEU A7052
1.38A
None
SFG  A7103 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.68A
None
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS D4333
ASP C6900
VAL D4295
ALA C6877
ASP C6897
1.77A
None
None
None
None
SFG  C7103 ( 2.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.53A
SFG  A7103 ( 3.5A)
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.44A
SFG  C7103 ( 3.5A)
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY C6911
VAL C6902
SER C6896
ALA C6870
ALA C6877
1.77A
 NA  C7102 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.75A
 NA  A7102 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A
None
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY C6879
GLY C6869
ARG C6884
ALA C6905
ASP C6906
1.48A
SFG  C7103 ( 3.5A)
SFG  C7103 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.49A
SFG  A7103 ( 3.5A)
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
PHE C7048
TYR C6845
LEU C7052
1.40A
None
SFG  C7103 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.78A
 NA  A7102 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
HIS B4336
GLY B4341
VAL B4361
ALA B4324
ASP A6904
1.58A
 ZN  B4401 ( 3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.72A
None
SFG  A7103 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
PHE B 342
TYR B 194
LEU B 249
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
PHE A 123
TYR A 180
LEU A 120
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
PHE B 123
TYR B 180
LEU B 120
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
PHE A 342
TYR A 194
LEU A 249
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
PHE A 219
TYR A 209
LEU A 286
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.72A
None
None
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.72A
None
None
APR  B 201 (-4.5A)
APR  B 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.73A
None
None
APR  A 201 (-4.4A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.70A
None
None
None
APR  D 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.67A
None
None
None
APR  C 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.76A
None
None
None
APR  D 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.74A
None
None
None
APR  C 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.72A
None
None
APR  D 201 (-4.3A)
APR  D 201 (-3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.71A
None
None
APR  B 201 (-4.5A)
APR  B 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.71A
None
None
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.71A
None
None
APR  D 201 (-4.3A)
APR  D 201 (-3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.74A
None
None
APR  A 201 (-4.4A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.64A
None
None
None
APR  C 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.70A
None
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.50A
SAH  A7101 (-3.5A)
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
HIS B4336
GLY B4341
VAL B4361
ALA B4324
ASP A6904
1.60A
 ZN  B4401 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.51A
SAH  A7101 (-3.5A)
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.73A
None
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6879
GLY A6869
ARG A6884
ALA A6905
ASP A6906
1.46A
SAH  A7101 (-3.5A)
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
GLY A6869
ASP A6895
ALA A6881
ASP A6904
1.74A
None
SAH  A7101 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6911
VAL A6902
SER A6896
ALA A6870
ALA A6877
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 258
VAL A 296
ALA A 211
ALA A 210
ASP A 216
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		3 / 3
PHE A 241
TYR A 213
LEU A 118
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6y2e REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.24A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6y2e REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.20A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6y2e REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.24A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
PHE A   3
TYR B 126
LEU A 286
1.35A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.72A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.75A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.72A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ASP A 197
GLY A 183
PHE A 185
ALA A 194
ALA A 193
1.75A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.66A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.34A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 258
VAL A 296
ALA A 211
ALA A 210
ASP A 216
1.76A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.66A25.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN E 409
GLY E 416
ARG E 457
ALA E 352
ASP E 467
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE H 170
TYR L 179
LEU H 174
1.40A
None
None
MLI  H 304 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE C  77
TYR C  98
LEU C  53
0.72A
None
DMS  C 303 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE L  77
TYR L  98
LEU L  53
0.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 409
GLY A 416
ARG A 457
ALA A 352
ASP A 467
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE L  77
TYR L  98
LEU L  53
0.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN E 409
GLY E 416
ARG E 457
ALA E 352
ASP E 467
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  36
GLY A 146
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
HIS A 164
GLY A 174
ASP A 187
VAL A  20
GLY A 146
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE B 170
TYR C 179
LEU B 174
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN E 409
GLY E 416
ARG E 457
ALA E 352
ASP E 467
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE L  77
TYR L  98
LEU L  53
0.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 409
GLY A 416
ARG A 457
ALA A 352
ASP A 467
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE C  77
TYR C  98
LEU C  53
0.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE H 170
TYR L 179
LEU H 174
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.63A
None
None
None
EDO  D 205 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.77A
None
None
EDO  D 211 (-3.7A)
EDO  D 205 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 103
GLY E  97
ALA E 134
ALA E 129
ASP E 135
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 103
GLY B  97
ALA B 134
ALA B 129
ASP B 135
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 103
GLY E  97
ALA E 134
ALA E 129
ASP E 135
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.69A
None
None
EDO  A 202 (-4.3A)
EDO  A 202 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.63A
None
None
None
EDO  D 205 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 133
VAL E  41
SER E 128
ALA E  38
ALA E  39
1.66A
None
None
EPE  E 202 (-4.6A)
EPE  E 202 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.68A
None
None
EDO  A 202 (-4.3A)
EDO  A 202 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.75A
None
None
EDO  C 208 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 133
VAL E  41
SER E 128
ALA E  38
ALA E  39
1.67A
None
None
EPE  E 202 (-4.6A)
EPE  E 202 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 103
GLY B  97
ALA B 134
ALA B 129
ASP B 135
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.67A
None
None
None
APR  D 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.72A
EDO  A 205 (-3.4A)
None
APR  A 201 (-4.4A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.73A
None
None
EDO  A 204 ( 3.9A)
APR  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.74A
None
None
None
APR  D 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.70A
None
None
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 103
GLY B  97
ALA B 134
ALA B 129
ASP B 135
1.75A
None
None
None
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 103
GLY B  97
ALA B 134
ALA B 129
ASP B 135
1.68A
None
None
None
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 103
GLY E  97
ALA E 134
ALA E 129
ASP E 135
1.70A
None
None
None
APR  E 201 (-3.5A)
EDO  B 202 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.69A
None
None
APR  D 201 (-4.3A)
APR  D 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 103
GLY E  97
ALA E 134
ALA E 129
ASP E 135
1.63A
None
None
None
APR  E 201 (-3.5A)
EDO  B 202 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 133
VAL E  41
SER E 128
ALA E  38
ALA E  39
1.72A
None
None
APR  E 201 (-4.4A)
APR  E 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 103
GLY D  97
ALA D 134
ALA D 129
ASP D 135
1.64A
None
None
None
APR  D 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 133
VAL E  41
SER E 128
ALA E  38
ALA E  39
1.73A
None
None
APR  E 201 (-4.4A)
APR  E 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.67A
None
None
None
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E 103
GLY E  97
ALA E 134
ALA E 129
ASP E 135
1.59A
None
None
None
APR  E 201 (-3.5A)
EDO  B 202 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.70A
None
None
APR  C 201 (-4.4A)
APR  C 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.75A
None
None
None
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.68A
None
None
APR  B 201 (-4.3A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.71A
EDO  A 205 (-3.4A)
None
APR  A 201 (-4.4A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.69A
None
None
APR  B 201 (-4.3A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.69A
None
None
EDO  A 204 ( 3.9A)
APR  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 103
GLY C  97
ALA C 134
ALA C 129
ASP C 135
1.64A
None
None
None
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D 133
VAL D  41
SER D 128
ALA D  38
ALA D  39
1.70A
None
None
APR  D 201 (-4.3A)
APR  D 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.64A
None
None
EDO  A 204 ( 3.9A)
APR  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.62A
None
None
MES  C 201 (-4.6A)
MES  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 103
GLY B  97
ALA B 134
ALA B 129
ASP B 135
1.75A
None
None
EDO  B 204 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.66A
None
None
MES  A 201 (-4.4A)
MES  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.77A
None
None
EDO  A 205 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B 133
VAL B  41
SER B 128
ALA B  38
ALA B  39
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A   8
ARG B 141
ALA A  21
ALA A 154
ASP A  22
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C 133
VAL C  41
SER C 128
ALA C  38
ALA C  39
1.63A
None
None
MES  C 201 (-4.6A)
MES  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 133
VAL A  41
SER A 128
ALA A  38
ALA A  39
1.65A
None
None
MES  A 201 (-4.4A)
MES  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ASP B 145
GLY A   8
ALA A  21
ALA A 154
ASP A  22
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ASP B 145
GLY A   8
ALA A  21
ALA A 154
ASP A  22
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ASP B 145
GLY A   8
ALA A  21
ALA A 154
ASP A  22
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A 103
GLY A  97
ALA A 134
ALA A 129
ASP A 135
1.72A
None
None
EDO  A 205 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A   8
ARG B 141
ALA A  21
ALA A 154
ASP A  22
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A   8
ARG B 141
ALA A  21
ALA A 154
ASP A  22
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 120
GLY A 146
PHE A 140
ALA A 116
CYH A 128
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A 192
TYR A  87
LEU A 187
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A 313
TYR A 286
LEU A 351
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 4
PHE A  45
TYR A 788
VAL A 233
LEU A 205
1.60A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A 741
TYR A 748
LEU A 470
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 205
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 129
LEU A 205
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A  45
TYR A 788
LEU A 205
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 4
PHE A  35
TYR A 129
VAL A 233
LEU A 205
1.56A12.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 708
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
GLN A 541
GLY A 503
SER A 561
ALA A 375
ASP A 377
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
VAL A 296
GLY A 302
ALA A 211
ALA A 210
ASP A 216
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY A 170
ARG A 131
ALA A 194
ASP A 197
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 189
VAL A 171
PHE A 185
ALA A 193
ALA A 194
1.52A
DMS  A 405 (-2.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
GLY A 345
VAL A 398
GLY A 327
ALA A 379
ALA A 382
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ASP A 421
VAL A 435
GLY A 839
PHE A 419
ALA A 423
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A 741
TYR A 748
LEU A 470
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A  45
TYR A 788
LEU A 205
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
GLY A 345
VAL A 398
GLY A 327
ALA A 379
ALA A 382
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 4
PHE A  35
TYR A 129
VAL A 233
LEU A 205
1.54A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A 192
TYR A  87
LEU A 187
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
GLY A 683
GLY A 503
SER A 501
ALA A 512
ASP A 499
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 4
PHE A  45
TYR A 788
VAL A 233
LEU A 205
1.61A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 708
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ASP A 421
VAL A 435
GLY A 839
PHE A 419
ALA A 423
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 129
LEU A 205
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 205
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 4
PHE A  35
TYR A 129
VAL A 204
LEU A 205
1.77A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
PHE A 192
TYR A  87
LEU A 187
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 4
PHE A  45
TYR A 788
VAL A 233
LEU A 205
1.61A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
PHE A 741
TYR A 748
LEU A 470
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 4
PHE A  35
TYR A 129
VAL A 233
LEU A 205
1.62A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 708
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
PHE A 313
TYR A 286
LEU A 351
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 535
SER A 649
PHE A 652
ARG A 651
ALA A 656
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
PHE A  35
TYR A 122
LEU A 205
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
GLN A 357
GLY A 345
PHE A 348
ALA A 656
ALA A 660
1.71A
None