Ligand ID: CED


Drugbank ID:
DB04133
(Degraded Cephaloridine)


Indication:

Get human targets for CED in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'CED'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
ALA B 116
TYR B 118
ASN B  28
GLY B 124
ARG A 298
1.74A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA B  54
TYR B  87
THR B  18
GLY B  17
ALA B  16
1.62A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA A  16
HIS A  48
ASN A  27
ALA A  15
ARG A  55
1.71A19.70
None
SO4  A 693 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 144
TYR B 161
SER B 147
ILE B 136
GLY B 143
1.74A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.57A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.59A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.42A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A  28
GLY A 124
ALA A 116
TYR A 126
1.41A24.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.39A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 144
SER B 147
ASN B  28
ASN B 119
GLY B 143
1.58A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		1uw7 NSP9
(SARS-COV
HKU-39849)		5 / 12
ALA A  16
HIS A  48
ASN A  27
ALA A  15
ARG A  55
1.70A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 11
ALA B 232
TYR B 250
SER B 247
ASN B 219
ALA B 221
1.74A21.05
GOL  B1004 (-3.5A)
None
None
None
GOL  B1004 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.63A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.63A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.64A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA B 294
ASN B 299
SER B 262
GLY B 260
ALA B 293
1.64A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
SER F 156
ASN F 114
ASN F 110
ALA F 157
ARG F 195
1.52A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 12
SER F 156
ASN F 114
ASN F 110
ALA F 157
ARG F 195
1.52A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2ajf ACE2
(Homo
sapiens)		5 / 12
ALA B  46
SER B  47
ASN B  51
ILE B  54
SER B  43
1.65A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
ALA F 314
SER F 313
TYR E 269
GLY F 317
ARG E 278
1.63A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
LYS L 167
ASN L 172
GLU L  83
ALA L  84
TYR L  86
1.50A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ASN C 100
ASN B 100
ASN C  41
GLY C  47
ALA C  51
1.59A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA A 113
ASN A 118
SER A  81
GLY A  79
ALA A 112
1.62A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 11
ALA B  51
TYR B  69
SER B  66
ASN B  38
ALA B  40
1.74A21.18
APR  B 477 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA A 113
ASN A 118
SER A  81
GLY A  79
ALA A 112
1.61A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ASN C 100
ASN B 100
ASN C  41
GLY C  47
ALA C  51
1.59A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER C 246
ASN C 263
THR C 211
GLY C 210
ALA C 247
1.75A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER C 246
ASN C 263
THR C 211
GLY C 210
ALA C 247
1.73A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER B 246
ASN B 263
THR B 211
GLY B 210
ALA B 247
1.67A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  33
SER B  52
ASN B  74
SER B  56
ARG A 426
1.61A21.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  33
SER B  52
ASN B  74
SER B  56
ARG A 426
1.58A21.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.38A23.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.44A23.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.71A23.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 142
GLY A 124
ALA A 116
TYR A 126
1.69A23.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.72A22.42
SAH  A1293 (-4.1A)
SAH  A1293 (-4.8A)
SAH  A1293 (-3.8A)
SAH  A1293 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2xyq NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.79A23.16
None
SAH  A1293 (-4.1A)
SAH  A1293 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		2xyr NSP10
PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.78A21.24
None
SFG  A1298 ( 4.2A)
SFG  A1298 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.70A22.29
SFG  A1298 ( 4.2A)
SFG  A1298 (-4.6A)
SFG  A1298 (-3.5A)
SFG  A1298 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  65
ASN B  58
TYR B  50
SER B  47
GLY B  66
1.48A18.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B  65
ASN B  58
TYR B  50
SER B  47
GLY B  66
1.48A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER A 105
SER A 113
ASN A 117
SER A 106
GLY A 104
1.63A18.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.68A22.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.66A23.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 11
ALA A  16
ASN A  27
THR A  18
GLY A  17
ALA A  22
1.74A18.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ALA B  28
SER B  46
HIS B  48
ASN B  27
ALA B  16
1.76A18.66
None
None
PO4  B 122 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA B 140
SER B 144
TYR B 161
SER B 147
ILE B 136
1.77A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LYS A   2
SER B 139
ASN A 214
ILE A 213
ARG A 298
1.79A20.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 116
SER A 144
ASN A  28
GLY A 143
TYR A 161
1.69A23.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.54A23.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.50A24.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 123
ASN A 119
GLY A 124
ALA A 116
TYR A 126
1.52A24.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.43A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 123
ASN B 142
GLY B 124
ALA B 116
TYR B 126
1.41A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER B 246
ASN B 263
THR B 211
GLY B 210
ALA B 247
1.69A22.22
None
None
None
GRM  A 801 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ASN B 129
SER A  79
THR B 201
GLY B 202
ALA B 182
1.66A21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ASN B 129
SER A  79
THR B 201
GLY B 202
ALA B 182
1.69A21.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 10
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.75A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.72A23.77
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 11
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.76A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.79A23.58
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.77A23.58
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A  74
TYR A  47
ASN A  43
GLY A  73
ALA A  72
1.75A24.49
SAM  A 302 ( 4.4A)
SAM  A 302 (-4.5A)
SAM  A 302 (-3.5A)
SAM  A 302 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
NSP10 AND NSP11
(SARSr-CoV)		5 / 12
ALA A  79
SER A  74
ASN A  43
GLY A  77
ARG B  78
1.77A24.49
None
SAM  A 302 ( 4.4A)
SAM  A 302 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER B 105
SER B 113
ASN B 117
SER B 106
GLY B 104
1.54A18.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A  65
ASN A  58
TYR A  50
SER A  47
GLY A  66
1.64A18.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
ALA A  65
TYR A  50
SER A  47
ASN A  61
GLY A  66
1.54A18.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A  65
ASN A  58
TYR A  50
SER A  47
GLY A  66
1.50A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER A 246
ASN A 263
THR A 211
GLY A 210
ALA A 247
1.67A21.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		4mm3 PAPAIN-LIKE
PROTEINASE
(SARSr-CoV)		5 / 12
SER B 181
ASN B 129
ASN B 178
GLU B 180
ALA B 182
1.75A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		4tww 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
ILE A 136
SER A 123
GLY A 124
ARG B 298
1.78A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.76A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.78A17.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ALA B 270
SER B 271
ASN B 266
GLY B 110
ALA B 274
1.78A18.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
ALA D 150
TYR D  36
SER D  86
THR D 159
ALA D 154
1.78A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.62A20.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.61A20.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.58A19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5f22 NSP8
(SARSr-CoV)		5 / 12
SER B 156
ASN B 114
ASN B 110
ALA B 157
ARG B 195
1.58A19.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
ALA D 270
SER D 271
ASN D 266
GLY D 110
ALA D 274
1.78A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA D  40
TYR D  28
ILE D  45
SER D  86
GLY D  39
1.55A22.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 753
SER B 750
TYR A 300
ILE A 299
SER B 717
1.58A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.29
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.29
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 11
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.34A21.01
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A20.73
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.33A21.01
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ALA A 311
SER A 126
ASN A 125
ALA A 122
ARG A  46
1.35A20.73
None
None
NAG  A 502 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
LYS A1100
SER A 852
ASN A 848
SER C1114
GLY C1115
1.37A11.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 11
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.44A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.45A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 861
TYR A 689
THR B 863
GLY B 862
ALA B 866
1.45A12.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA C 753
SER C 750
TYR B 598
ILE B 299
SER C 717
1.51A11.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ASN C1090
THR A 863
GLY A 867
ALA A 866
TYR A 771
1.77A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.31A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.30A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.30A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.31A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ALA B 311
SER B 126
ASN B 125
ALA B 122
ARG B  46
1.29A11.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN B1116
HIS B1065
GLY B1113
ALA B1062
TYR A 899
1.77A12.22
ASN  B1116 ( 0.6A)
HIS  B1065 ( 1.0A)
GLY  B1113 ( 0.0A)
ALA  B1062 ( 0.0A)
TYR  A 899 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA C 866
ASN A1056
THR C 869
GLY C 867
ALA C 875
1.70A12.02
ALA  C 866 ( 0.0A)
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 875 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA C 866
ASN A1056
THR C 869
GLY C 867
ALA C 875
1.72A12.22
ALA  C 866 ( 0.0A)
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 875 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN A1056
THR C 869
GLY C 867
ALA C 866
TYR C 771
1.22A12.22
ASN  A1056 ( 0.6A)
THR  C 869 ( 0.8A)
GLY  C 867 ( 0.0A)
ALA  C 866 ( 0.0A)
TYR  C 771 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
ALA A 858
SER A 861
TYR B 689
THR A 863
GLY A 862
1.73A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A1052
GLU A1054
GLY C 873
ALA C 874
TYR C 771
1.48A12.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
ALA B 639
TYR B 598
THR B 624
GLY B 638
ALA B 595
1.70A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 111
ASN A 129
ILE B 455
GLN A 112
GLY A 104
1.65A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 639
TYR B 598
THR B 624
GLY B 638
ALA B 595
1.69A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B1093
ASN B 896
GLU C1074
THR B1087
ARG B1073
1.67A12.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ASN A1056
THR C 869
GLY C 867
ALA C 866
TYR C 771
1.51A12.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ALA C 590
SER C 591
SER C 592
THR C 588
GLY C 587
1.74A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER A 861
TYR C 689
THR A 863
GLY A 862
ALA A 866
1.78A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 590
SER B 591
SER B 592
THR B 588
GLY B 587
1.71A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 954
SER B 956
GLN B 974
SER B 957
ARG B 982
1.54A11.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 680
SER B 645
GLU B 647
GLY B 682
ALA B 683
1.58A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
SER C 861
TYR B 689
THR C 863
GLY C 862
ALA C 866
1.62A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA A 875
TYR A 886
GLY A 871
ALA A 872
TYR C1029
1.48A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.55A12.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.57A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 237
ASN B 135
ASN B  78
THR B 247
GLY B 246
1.57A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
ALA B 858
SER B 861
TYR A 689
THR B 863
GLY B 862
1.63A12.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 12
SER D 105
SER D 113
ASN D 117
SER D 106
GLY D 104
1.76A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ALA B 379
ASN B 124
TYR B 120
ASN B 423
ALA B 407
1.73A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
SER F 967
ASN D 969
GLN D 965
SER F1170
GLY F1171
1.50A23.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER A  19
TYR A  83
GLY B 476
ALA B 475
TYR B 489
1.61A17.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m0j ACE2
(Homo
sapiens)		5 / 12
SER A 105
SER A 113
ASN A 117
SER A 106
GLY A 104
1.73A18.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
TYR D  83
GLU D  23
THR F 478
GLY F 476
ALA F 475
1.50A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ALA C 117
SER C 118
ILE C 496
SER C 100
GLY C 115
1.38A16.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6m18 ACE2
(Homo
sapiens)		5 / 12
SER D 105
SER D 113
ASN D 117
SER D 106
GLY D 104
1.65A16.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 12
ALA B  65
SER B  43
ASN B  49
ASN B  61
GLY B  66
1.71A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 12
ALA B  65
SER B  43
ASN B  49
ASN B  61
GLY B  66
1.67A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA D 153
TYR A 112
ASN D 154
GLY A 121
ALA A 120
1.62A20.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.44A15.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 11
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.51A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.38A11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.39A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 861
TYR C 689
THR B 863
GLY B 862
ALA B 866
1.41A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B1105
TYR A 899
ASN A 896
GLY B1106
ALA B1069
1.78A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 938
ASN A 838
ASN A 942
ALA A 940
ARG A 996
1.65A11.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.37A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6nur NSP8
(SARSr-CoV)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.59A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
SER A 709
ASN A 703
ASN A 781
ARG A 132
TYR A 788
1.52A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6nur NSP8
(SARSr-CoV)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.58A22.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 11
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.43A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 892
SER B 884
GLU A1072
GLY B 891
TYR A1047
1.59A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA C 879
ASN B 703
ILE C 788
SER C 884
GLY C 880
1.68A11.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 703
SER B 884
THR B 887
GLY B 891
ALA B 892
1.45A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 703
SER B 884
THR B 887
GLY B 891
ALA B 892
1.39A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
ALA A 653
TYR A 612
LYS A 640
GLY A 652
ALA A 609
1.72A12.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN A 703
SER B 884
THR B 887
GLY B 891
ALA B 892
1.41A11.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER F 477
THR F 478
GLY F 476
ALA F 475
TYR F 489
1.58A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA C 879
ASN B 703
SER C 884
THR C 881
ALA C 876
1.72A11.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 879
ASN A 703
SER B 884
THR B 881
ALA B 876
1.75A11.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN C 703
SER A 884
THR A 887
GLY A 891
ALA A 892
1.71A11.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 879
ASN A 703
SER B 884
THR B 881
ALA B 876
1.71A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN C 703
SER A 884
THR A 887
GLY A 891
ALA A 892
1.66A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN C 703
SER A 884
THR A 887
GLY A 891
ALA A 892
1.73A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
SER B 884
ASN A 703
THR B 887
GLY B 891
ALA B 892
1.78A12.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w02 NSP3
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.65A23.60
APR  A 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6w02 NSP3
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.72A23.60
APR  A 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ALA L  51
SER L  52
ASN L  29
ASN L  31
THR L  53
1.33A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
SER C 477
THR C 478
GLY C 476
ALA C 475
TYR C 489
1.74A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6w4b NSP9
(SARS-CoV-2)		5 / 11
ALA B  17
ASN B  28
THR B  19
GLY B  18
ALA B  23
1.70A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6w4b NSP9
(SARS-CoV-2)		5 / 12
ALA B  17
ASN B  28
THR B  19
GLY B  18
ALA B  23
1.69A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w4b NSP9
(SARS-CoV-2)		5 / 12
ALA B  17
ASN B  28
THR B  19
GLY B  18
ALA B  23
1.66A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6w4h NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6877
SER A6872
ASN A6841
GLY A6875
ARG B4331
1.80A20.27
None
SAM  A7102 ( 4.5A)
SAM  A7102 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6w4h NSP16
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.75A20.69
SAM  A7102 ( 4.5A)
SAM  A7102 (-4.5A)
SAM  A7102 (-3.6A)
SAM  A7102 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.71A
SAM  A7104 (-4.4A)
SAM  A7104 (-4.6A)
SAM  A7104 (-3.3A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6877
SER A6872
ASN A6841
GLY A6875
ARG B4331
1.75A
None
SAM  A7104 (-4.4A)
SAM  A7104 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.71A
SAM  A7104 (-4.4A)
SAM  A7104 (-4.6A)
SAM  A7104 (-3.3A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.68A
MES  B 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6w6y NSP3
(SARS-CoV-2)		5 / 11
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.75A
MES  B 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6877
SER C6872
ASN C6841
GLY C6875
ARG D4331
1.79A19.92
None
SAM  C7105 ( 4.4A)
SAM  C7105 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.76A19.69
SAM  A7102 ( 4.6A)
SAM  A7102 ( 4.5A)
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.75A19.69
SAM  A7102 ( 4.6A)
SAM  A7102 ( 4.5A)
SAM  A7102 ( 3.4A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER C6872
TYR C6845
ASN C6841
GLY C6871
ALA C6870
1.74A19.69
SAM  C7105 ( 4.4A)
SAM  C7105 ( 4.5A)
SAM  C7105 ( 3.7A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER C6872
TYR C6845
ASN C6841
GLY C6871
ALA C6870
1.74A19.69
SAM  C7105 ( 4.4A)
SAM  C7105 ( 4.5A)
SAM  C7105 ( 3.7A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 136
GLU A 143
THR A 102
GLY A 142
ALA A 141
1.55A20.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ASN C 146
GLU C 143
THR C 102
GLY C 142
ALA C 141
1.68A20.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR C 136
GLU C 143
THR C 102
GLY C 142
ALA C 141
1.53A20.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA B 114
SER B 103
ASN B 110
GLY B 287
TYR A 268
1.78A
 CL  B 502 ( 3.8A)
CL  B 502 ( 4.4A)
None
CL  B 502 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA B 114
SER B 103
ASN B 110
GLY B 287
TYR A 268
1.78A
 CL  B 502 ( 3.8A)
CL  B 502 ( 4.4A)
None
CL  B 502 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6wcf NSP3
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.73A
MES  A 201 ( 3.0A)
None
None
None
MES  A 201 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.67A
MES  A 201 ( 3.0A)
None
None
None
MES  A 201 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wen NSP3
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6wen NSP3
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wey NSP3
(SARS-CoV-2)		5 / 12
ALA A 254
TYR A 272
SER A 269
ASN A 241
ALA A 243
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6wey NSP3
(SARS-CoV-2)		5 / 11
ALA A 254
TYR A 272
SER A 269
ASN A 241
ALA A 243
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6wiq NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.70A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wiq NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6wiq NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.67A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6wiq NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.66A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA E 313
SER E 312
TYR F 268
GLY E 316
ARG F 277
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER C6872
TYR C6845
ASN C6841
GLY C6871
ALA C6870
1.79A
SAH  C7102 (-4.7A)
SAH  C7102 (-4.6A)
SAH  C7102 (-3.7A)
SAH  C7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA C6877
SER C6872
ASN C6841
GLY C6875
ARG D4331
1.77A
None
SAH  C7102 (-4.7A)
SAH  C7102 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.77A
SAH  A7102 ( 4.6A)
SAH  A7102 (-4.6A)
SAH  A7102 (-3.6A)
SAH  A7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.78A
SAH  A7102 ( 4.6A)
SAH  A7102 (-4.6A)
SAH  A7102 (-3.6A)
SAH  A7102 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6877
SER A6872
ASN A6841
GLY A6875
ARG B4331
1.78A
None
SAH  A7102 ( 4.6A)
SAH  A7102 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA B 156
ASN C 150
ASN C 154
LYS A 156
ALA B 155
1.72A18.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA B 156
ASN C 150
ASN C 154
LYS A 156
ALA B 155
1.72A18.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.77A
SFG  A7103 ( 4.5A)
SFG  A7103 ( 4.6A)
FMT  A7104 ( 3.1A)
SFG  A7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6877
SER C6872
ASN C6841
GLY C6875
ARG D4331
1.79A
None
SFG  C7103 ( 4.5A)
FMT  C7112 ( 3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C6872
TYR C6845
ASN C6841
GLY C6871
ALA C6870
1.76A
SFG  C7103 ( 4.5A)
SFG  C7103 ( 4.5A)
FMT  C7112 ( 3.3A)
SFG  C7103 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C6872
TYR C6845
ASN C6841
GLY C6871
ALA C6870
1.76A
SFG  C7103 ( 4.5A)
SFG  C7103 ( 4.5A)
FMT  C7112 ( 3.3A)
SFG  C7103 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.76A
SFG  A7103 ( 4.5A)
SFG  A7103 ( 4.6A)
FMT  A7104 ( 3.1A)
SFG  A7103 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.71A
APR  D 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.66A
APR  C 201 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.73A
APR  C 201 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.67A
APR  B 201 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.64A
APR  D 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.64A
APR  A 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.71A
APR  A 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.74A
APR  B 201 (-3.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.74A
SO4  A7109 (-4.5A)
SAH  A7101 (-4.5A)
SO4  A7109 ( 3.2A)
SAH  A7101 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6872
TYR A6845
ASN A6841
GLY A6871
ALA A6870
1.75A
SO4  A7109 (-4.5A)
SAH  A7101 (-4.5A)
SO4  A7109 ( 3.2A)
SAH  A7101 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6877
SER A6872
ASN A6841
GLY A6875
ARG B4331
1.77A
None
SO4  A7109 (-4.5A)
SO4  A7109 ( 3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.55A20.00
None
None
EDO  B 301 (-3.9A)
EDO  B 302 ( 4.3A)
EDO  B 302 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.60A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.58A20.00
None
None
EDO  B 301 (-3.9A)
EDO  B 302 ( 4.3A)
EDO  B 302 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.55A20.00
None
None
EDO  B 301 (-3.9A)
EDO  B 302 ( 4.3A)
EDO  B 302 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.60A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.63A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER B 151
ASN B 109
ASN B 105
ALA B 152
ARG B 190
1.58A
None
None
EDO  B 301 (-3.9A)
EDO  B 302 ( 4.3A)
EDO  B 302 (-2.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
TYR D 149
ASN D 105
ALA D 152
ARG D 190
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.59A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.62A17.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
SER D 151
ASN D 109
ASN D 105
ALA D 152
ARG D 190
1.59A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.74A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER C  73
ASN C  35
ASN C  37
GLY C  72
ALA C  57
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 530
ASN A 334
ASN A 532
GLY A 526
ALA A 363
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA C  57
SER C  58
ASN C  35
THR C  59
TYR C  97
1.76A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 477
THR A 478
GLY A 476
ALA A 475
TYR A 489
1.57A24.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER E 477
THR E 478
GLY E 476
ALA E 475
TYR E 489
1.61A24.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  73
ASN L  35
ASN L  37
GLY L  72
ALA L  57
1.61A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.75A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ALA L  57
SER L  58
ASN L  35
THR L  59
TYR L  97
1.73A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER E 477
THR E 478
GLY E 476
ALA E 475
TYR E 489
1.61A24.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ALA C  57
SER C  58
ASN C  35
THR C  59
TYR C  97
1.73A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 477
THR A 478
GLY A 476
ALA A 475
TYR A 489
1.61A24.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.77A
EDO  D 206 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.71A
EDO  D 206 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  50
TYR E  68
SER E  65
ASN E  37
ALA E  39
1.68A
EPE  E 202 (-3.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA E  50
TYR E  68
SER E  65
ASN E  37
ALA E  39
1.75A
EPE  E 202 (-3.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.78A
APR  D 201 (-3.6A)
EDO  D 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.71A
APR  B 201 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA D  50
TYR D  68
SER D  65
ASN D  37
ALA D  39
1.71A
APR  D 201 (-3.6A)
EDO  D 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.77A
APR  A 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.67A
APR  C 201 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.70A
APR  A 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.74A
APR  C 201 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA E  50
TYR E  68
SER E  65
ASN E  37
ALA E  39
1.75A
APR  E 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  50
TYR E  68
SER E  65
ASN E  37
ALA E  39
1.68A
APR  E 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.78A
APR  B 201 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.69A
MES  A 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.77A
MES  C 201 ( 3.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA A  50
TYR A  68
SER A  65
ASN A  37
ALA A  39
1.76A
MES  A 201 ( 3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
ALA B  50
TYR B  68
SER B  65
ASN B  37
ALA B  39
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  50
TYR C  68
SER C  65
ASN C  37
ALA C  39
1.70A
MES  C 201 ( 3.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ASN A 507
ASN A 543
GLY A 559
ALA A 558
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
HIS A 381
GLY A 385
ALA A 399
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
HIS A 381
GLY A 385
ALA A 399
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
LYS B  97
GLY A 385
ALA A 399
1.77A15.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 11
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
LYS B  97
GLY A 385
ALA A 382
1.65A15.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ASN A 507
ASN A 543
GLY A 559
ALA A 558
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ASN A 507
ASN A 543
GLY A 559
ALA A 558
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
SER A 501
ASN A 507
ASN A 543
GLY A 559
ALA A 558
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ASN A 507
ASN A 543
GLY A 559
ALA A 558
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		7bv2 NSP8
(SARS-CoV-2)		5 / 11
ALA B 102
ASN B 109
ASN B 105
THR B 123
ARG B 190
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 660
ASN A 534
SER A 343
ASN A 356
ASN A 657
1.54A15.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.61A
None
U  T   9 ( 3.7A)
None
U  T  10 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
HIS A 381
GLY A 385
ALA A 399
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 383
SER A 384
HIS A 381
GLY A 385
ALA A 399
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 660
ASN A 534
SER A 343
ASN A 356
ASN A 657
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
TYR A 453
ASN A 543
THR A 540
GLY A 559
ALA A 558
1.69A
None
U  T   9 ( 3.7A)
None
U  T  10 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		7bv2 NSP8
(SARS-CoV-2)		5 / 10
ALA B 102
ASN B 109
ASN B 105
THR B 123
ARG B 190
1.79A20.65
None