 |
| Ligand ID: DP0 Drugbank ID: DB00280(Disopyramide) Indication:For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias. It is a Class Ia antiarrhythmic drug. |
| DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
View | Interface | RMSD | Seq. Identity (%) |
HETATM | Dock | |
|---|---|---|---|---|---|---|---|---|---|---|
 Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 1uj1 | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | PHE A 150VAL A 13PHE B 150ALA A 7SER A 113 | 1.72A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 1uj1 | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | VAL A 125PHE A 291PHE A 3ARG A 298PHE B 140 | 1.57A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2a5k | 3C-LIKE PEPTIDASE (SARSr-CoV) | 5 / 12 | PHE A 150VAL A 13PHE B 150ALA A 7SER A 113 | 1.72A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2ajf | SPIKE PROTEIN (SARSr-CoV) | 5 / 12 | VAL F 382ILE F 345PHE F 364LEU F 421TYR F 352 | 1.63A | 19.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2ajf | SPIKE PROTEIN (SARSr-CoV) | 5 / 12 | PHE E 501VAL E 382ILE E 345PHE E 329PHE E 361 | 1.65A | 19.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2amd | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | PHE A 150VAL A 13PHE B 150ALA A 7SER A 113 | 1.72A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2d2d | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | VAL A 125PHE A 291PHE A 3ARG A 298ALA B 116 | 1.67A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2ghw | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | VAL C 394ILE C 397PHE C 329PHE C 360SER C 362 | 1.67A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2k87 | NSP3 OF REPLICASEPOLYPROTEIN 1A (SARSr) | 5 / 12 | PHE A 74ILE A 7GLU A 4SER A 73TYR A 2 | 1.30A | 21.24 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2ofz | NUCLEOCAPSID PROTEIN (SARS-COVTor2) | 5 / 12 | ILE A 75PHE A 111ALA A 139SER A 79TYR A 113 | 1.55A | 18.23 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2ofz | NUCLEOCAPSID PROTEIN (SARS-COVTor2) | 5 / 12 | ILE A 75PHE A 111ALA A 139SER A 79TYR A 113 | 1.57A | 18.23 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2q6g | REPLICASEPOLYPROTEIN 1AB (SARS-COVBJ01) | 5 / 12 | ILE B 106PHE B 291GLN B 110ARG B 298ALA B 7 | 1.58A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2q6g | REPLICASEPOLYPROTEIN 1AB (SARS-COVBJ01) | 5 / 12 | PHE A 150PHE B 150ALA A 7SER A 113SER A 10 | 1.73A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2qc2 | 3C-LIKE PROTEINASE (-) | 5 / 12 | VAL A 13LEU B 115GLU B 14ALA B 7SER A 113 | 1.61A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2rhb | URIDYLATE-SPECIFICENDORIBONUCLEASE (SARSr-CoV) | 5 / 12 | PHE A 43VAL A 51ILE E 26GLU E 3ALA A 59 | 1.58A | 20.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 2vj1 | MAIN PROTEINASE (SARSr-CoV) | 5 / 12 | PHE A 112GLU A 290PHE A 140SER A 139TYR A 126 | 1.68A | 22.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3aw1 | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | PHE A 150VAL A 13PHE B 150ALA A 7SER A 113 | 1.72A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3bgf | F26G19 FAB (Musmusculus) | 5 / 12 | TYR C 91ILE C 2GLU C 28ALA C 50TYR C 71 | 1.52A | 21.52 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3bgf | SPIKE PROTEIN S1 (SARSr-CoV) | 5 / 12 | PHE A 329VAL A 497PHE A 501PHE A 379ALA A 350 | 1.66A | 19.18 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3f9f | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | PHE B 150VAL B 13PHE A 150ALA B 7SER B 113 | 1.70A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3f9g | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | VAL B 125PHE B 291PHE B 3ARG B 298ALA A 116 | 1.56A | 21.36 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3m3v | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | VAL A 125PHE A 291PHE A 3ARG A 298ALA B 116 | 1.63A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3m3v | 3C-LIKE PROTEINASE (SARSr-CoV) | 5 / 12 | PHE B 150VAL B 13PHE A 150ALA B 7SER B 113 | 1.71A | 20.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3scj | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | VAL E 382ILE E 345PHE E 364LEU E 421TYR E 352 | 1.54A | 21.76 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 3sck | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | VAL E 382ILE E 345PHE E 364LEU E 421TYR E 352 | 1.67A | 22.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 4m0w | REPLICASEPOLYPROTEIN 1A (SARSr-CoV) | 5 / 12 | VAL A 206PHE A 128PHE A 148GLN A 175ALA A 120 | 1.65A | 22.42 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5c8s | GUANINE-N7METHYLTRANSFERASE (SARSr-CoV) | 5 / 12 | TYR B 498VAL B 316ILE B 397PHE B 436PHE B 431 | 1.67A | 16.16 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5c8u | GUANINE-N7METHYLTRANSFERASE (SARSr-CoV) | 5 / 12 | VAL B 199ILE B 201GLU B 204ARG B 213ALA B 85 | 1.33A | 16.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5c8u | GUANINE-N7METHYLTRANSFERASE (SARSr-CoV) | 5 / 12 | PHE B 183VAL B 199ILE B 201GLU B 204ALA B 85 | 1.58A | 16.33 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5nfy | POLYPROTEIN 1AB (SARS-COVFrankfurt1) | 5 / 12 | VAL A 269PHE A 89PHE A 198GLU A 191ALA A 119 | 1.66A | 15.93 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5nfy | POLYPROTEIN 1AB (SARS-COVFrankfurt1) | 5 / 12 | VAL D 199ILE D 201GLU D 204ARG D 213ALA D 85 | 1.43A | 15.93 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5tl6 | REPLICASEPOLYPROTEIN 1AB (SARSr-CoV) | 5 / 12 | VAL D 206PHE D 128PHE D 148GLN D 175ALA D 120 | 1.66A | 20.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x4r | S PROTEIN (MERS-CoV) | 5 / 12 | TYR A 87VAL A 102ILE A 35PHE A 164ALA A 146 | 1.38A | 18.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x4r | S PROTEIN (MERS-CoV) | 5 / 12 | VAL A 263ILE A 290PHE A 228LEU A 187PHE A 183 | 1.54A | 18.13 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x58 | SPIKE GLYCOPROTEIN (SARS-COVBJ01) | 5 / 12 | PHE C 187VAL C 196ILE C 219PHE C 168ALA C 91 | 1.59A | 9.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x59 | S PROTEIN (MERS-CoV) | 5 / 12 | TYR A 87VAL A 102ILE A 35PHE A 164ALA A 146 | 1.36A | 8.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x5b | SPIKE GLYCOPROTEIN (SARS-COVBJ01) | 5 / 12 | PHE C 880PHE C 784GLN C 902ALA C 912PHE C 909 | 1.67A | 9.53 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5x5f | S PROTEIN (MERS-CoV) | 5 / 12 | ILE B1165ALA C 969PHE B 778SER B1151TYR B1153 | 1.44A | 8.97 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5xlr | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | ILE B 878PHE B 888LEU B1031GLN B 883ALA B 906 | 1.61A | 9.98 | ILE B 878 ( 0.6A)PHE B 888 ( 1.3A)LEU B1031 ( 0.6A)GLN B 883 ( 0.6A)ALA B 906 ( 0.0A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 5y3q | REPLICASEPOLYPROTEIN 1A (SARSr-CoV) | 5 / 12 | VAL A 206PHE A 128PHE A 148GLN A 175ALA A 120 | 1.66A | 22.15 | NoneNoneNoneNone NA A 404 ( 3.8A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6acd | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | TYR B1049PHE B1091VAL B 893ILE B 891PHE B 782 | 1.47A | 9.98 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6acg | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | VAL B 893ILE B 891PHE B1034GLN B1018PHE B 909 | 1.27A | 9.98 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6cs0 | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | ILE B 891PHE B1034GLN B1018ALA B 906PHE B 909 | 1.34A | 9.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6cs1 | SPIKEGLYCOPROTEIN,FIBRITIN (SARSr-CoV) | 5 / 12 | PHE B 545ILE C 46PHE B 558PHE C 837SER B 541 | 1.21A | 9.30 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6jyt | HELICASE (SARSr-CoV) | 5 / 12 | ILE A 376LEU A 417ARG A 409ALA A 123SER A 424 | 1.47A | 14.93 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6lzg | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE B 347VAL B 401ILE B 402PHE B 429ALA B 397 | 1.38A | 23.75 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m0j | ACE2 (Homosapiens) | 5 / 12 | TYR A 587PHE A 438ILE A 446GLU A 406ALA A 412 | 1.66A | 14.83 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m17 | RECEPTOR BINDINGDOMAIN (SARS-CoV-2) | 5 / 12 | PHE E 515VAL E 395ILE E 358PHE E 342PHE E 374 | 1.72A | 21.37 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m17 | SODIUM-DEPENDENTNEUTRAL AMINO ACIDTRANSPORTER B(0)AT1 (Homosapiens) | 5 / 12 | ILE C 309PHE C 74LEU C 75ALA C 318PHE C 58 | 1.52A | 12.82 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | PHE A 112GLU A 290SER C 1SER A 139TYR A 126 | 1.78A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | PHE C 150VAL C 13PHE A 150ALA C 7SER C 113 | 1.71A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | PHE A 150VAL A 13PHE C 150ALA A 7SER A 113 | 1.74A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | PHE D 150VAL D 13PHE B 150ALA D 7SER D 113 | 1.73A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m2n | 3CL PROTEASE (SARS-CoV-2) | 5 / 12 | PHE B 150VAL B 13PHE D 150ALA B 7SER B 113 | 1.75A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m3m | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE D 75PHE D 111ALA D 139SER D 79TYR D 113 | 1.60A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m3m | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE D 75PHE D 111ALA D 139SER D 79TYR D 113 | 1.63A | 20.00 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726ALA A 43 | 1.70A | 11.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 785PHE A 471PHE A 741LEU A 727GLN A 468 | 1.75A | 11.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6m71 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726PHE A 471 | 1.68A | 11.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6nb6 | SPIKE GLYCOPROTEIN (SARSr-CoV) | 5 / 12 | VAL A 382ILE A 345PHE A 329PHE A 361ALA A 371 | 1.65A | 9.74 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6nb8 | S230 ANTIGEN-BINDING(FAB) FRAGMENT,LIGHT CHAIN (Homosapiens) | 5 / 12 | VAL L 13ILE L 111GLU L 86ARG L 66TYR L 91 | 1.47A | 19.47 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vsb | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE A 896PHE A 906LEU A1049GLN A 901ALA A 924 | 1.60A | 9.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vsb | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | TYR B1067PHE B1109VAL B 911ILE B 909PHE B 800 | 1.51A | 9.72 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vxx | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE A 347VAL A 401ILE A 402PHE A 429ALA A 397 | 1.42A | 9.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vxx | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE A 909PHE A1052GLN A1036ALA A 924PHE A 927 | 1.26A | 9.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vyb | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE A 347VAL A 401ILE A 402PHE A 429ALA A 397 | 1.35A | 9.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vyb | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE B 909PHE B1052GLN B1036ALA B 924PHE B 927 | 1.23A | 9.68 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vyo | NUCLEOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE C 74PHE C 110ALA C 138SER C 78TYR C 112 | 1.48A | 17.30 | NoneNoneNoneGOL C 203 (-4.2A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6vyo | NUCLEOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE C 74PHE C 110ALA C 138SER C 78TYR C 112 | 1.50A | 17.30 | NoneNoneNoneGOL C 203 (-4.2A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w02 | NSP3 (SARS-CoV-2) | 5 / 12 | VAL B 100ILE B 106PHE B 116ALA B 39SER B 128 | 1.61A | 17.89 | NoneNoneNoneNoneAPR B 201 (-4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w02 | NSP3 (SARS-CoV-2) | 5 / 12 | VAL B 100ILE B 106PHE B 116ALA B 39SER B 128 | 1.67A | 17.89 | NoneNoneNoneNoneAPR B 201 (-4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w41 | SPIKE PROTEIN S1 (SARS-CoV-2) | 5 / 12 | PHE C 347VAL C 401ILE C 402PHE C 429ALA C 397 | 1.38A | 22.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w41 | SPIKE PROTEIN S1 (SARS-CoV-2) | 5 / 12 | VAL C 401ILE C 402PHE C 429LEU C 425ALA C 397 | 1.50A | 22.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w63 | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 125PHE A 291PHE A 3GLN A 127ARG A 298 | 1.73A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6w6y | NSP3 (SARS-CoV-2) | 5 / 12 | VAL B 100ILE B 106PHE B 116ALA B 38SER B 128 | 1.79A | NoneNoneNoneMES B 201 ( 3.4A)MES B 201 ( 4.5A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wcf | NSP3 (SARS-CoV-2) | 5 / 12 | VAL A 100ILE A 106PHE A 116ALA A 39SER A 128 | 1.56A | NoneNoneNoneMES A 201 ( 4.7A)MES A 201 (-4.4A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wcf | NSP3 (SARS-CoV-2) | 5 / 12 | VAL A 100ILE A 106PHE A 116ALA A 39SER A 128 | 1.61A | 20.62 | NoneNoneNoneMES A 201 ( 4.7A)MES A 201 (-4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wcf | NSP3 (SARS-CoV-2) | 5 / 12 | VAL A 100ILE A 106PHE A 116ALA A 38SER A 128 | 1.78A | NoneNoneNoneMES A 201 (-3.6A)MES A 201 (-4.4A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wiq | NSP7NSP8 (SARS-CoV-2) | 5 / 12 | ILE B 119PHE B 92LEU B 95ALA B 110SER A 61 | 1.79A | 20.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE C 130PHE C 110PHE C 53LEU C 159ALA C 50 | 1.77A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE B 74PHE B 110ALA B 138SER B 78TYR B 112 | 1.60A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE D 130PHE D 110PHE D 53LEU D 159ALA D 50 | 1.78A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE D 74PHE D 110ALA D 138SER D 78TYR D 112 | 1.60A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE A 74PHE A 110ALA A 138SER A 78TYR A 112 | 1.54A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE C 74PHE C 110ALA C 138SER C 78TYR C 112 | 1.61A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE C 74PHE C 110ALA C 138SER C 78TYR C 112 | 1.58A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE B 74PHE B 110ALA B 138SER B 78TYR B 112 | 1.58A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE A 74PHE A 110ALA A 138SER A 78TYR A 112 | 1.52A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wkp | NUCLEOCAPSID PROTEIN (SARS-CoV-2) | 5 / 12 | ILE D 74PHE D 110ALA D 138SER D 78TYR D 112 | 1.57A | 17.84 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wlc | URIDYLATE-SPECIFICENDORIBONUCLEASE (SARS-CoV-2) | 5 / 12 | VAL B 295PHE B 214PHE B 222GLU B 211PHE B 233 | 1.79A | 18.80 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL B 100ILE B 106PHE B 116ALA B 39SER B 128 | 1.66A | 21.00 | NoneNoneNoneNoneAPR B 201 (-4.5A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL D 100ILE D 106PHE D 116ALA D 39SER D 128 | 1.69A | 21.00 | NoneNoneNoneNoneAPR D 201 (-4.3A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL C 100ILE C 106PHE C 116ALA C 39SER C 128 | 1.72A | 21.00 | NoneNoneNoneNoneAPR C 201 (-4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 100ILE A 106PHE A 116ALA A 39SER A 128 | 1.70A | 21.00 | NoneNoneNoneNoneAPR A 201 (-4.4A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL D 100ILE D 106PHE D 116ALA D 39SER D 128 | 1.62A | NoneNoneNoneNoneAPR D 201 (-4.3A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL C 100ILE C 106PHE C 116ALA C 39SER C 128 | 1.66A | NoneNoneNoneNoneAPR C 201 (-4.4A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL B 100ILE B 106PHE B 116ALA B 39SER B 128 | 1.60A | NoneNoneNoneNoneAPR B 201 (-4.5A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6woj | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 100ILE A 106PHE A 116ALA A 39SER A 128 | 1.63A | NoneNoneNoneNoneAPR A 201 (-4.4A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wqd | NSP7NSP8 (SARS-CoV-2) | 5 / 12 | ILE D 119PHE D 92LEU D 95ALA D 110SER C 61 | 1.77A | 20.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wqd | NSP7NSP8 (SARS-CoV-2) | 5 / 12 | ILE B 119PHE B 92LEU B 95ALA B 110SER A 61 | 1.74A | 20.35 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6wqf | 3C-LIKE PROTEINASE (SARS-CoV-2) | 5 / 12 | VAL A 125PHE A 291PHE A 3GLN A 127ARG A 298 | 1.74A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6y2g | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | PHE B 150VAL B 13PHE A 150ALA B 7SER B 113 | 1.71A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yb7 | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 125PHE A 291PHE A 3GLN A 127ARG A 298 | 1.80A | 19.30 | NoneNoneNoneDMS A 403 (-3.4A)DMS A 403 (-3.9A) | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yhu | REPLICASEPOLYPROTEIN 1A (SARS-CoV-2) | 5 / 12 | ILE D 119PHE D 92LEU D 95ALA D 110SER C 61 | 1.71A | 21.23 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yi3 | NUCLEOPROTEIN (SARS-CoV-2) | 5 / 12 | TYR A 46ILE A 90PHE A 70PHE A 13ALA A 10 | 1.76A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yi3 | NUCLEOPROTEIN (SARS-CoV-2) | 5 / 12 | ILE A 90PHE A 70PHE A 13LEU A 119ALA A 10 | 1.79A | 20.51 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE A 347VAL A 401ILE A 402PHE A 429ALA A 397 | 1.33A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL E 401ILE E 402PHE E 429LEU E 425ALA E 397 | 1.47A | 24.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE E 347VAL E 401ILE E 402PHE E 429ALA E 397 | 1.36A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE E 515VAL E 395ILE E 358PHE E 342PHE E 374 | 1.75A | NoneNoneNoneNoneDMS E 901 (-4.4A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yla | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL A 401ILE A 402PHE A 429LEU A 425ALA A 397 | 1.49A | 24.34 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ym0 | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE E 347VAL E 401ILE E 402PHE E 429ALA E 397 | 1.37A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ynq | REPLICASEPOLYPROTEIN 1AB (SARS-CoV-2) | 5 / 12 | VAL A 125PHE A 291PHE A 3GLN A 127ARG A 298 | 1.76A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL E 401ILE E 402PHE E 429LEU E 425ALA E 397 | 1.46A | 22.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE A 515VAL A 395ILE A 358PHE A 342PHE A 374 | 1.75A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE E 515VAL E 395ILE E 358PHE E 342PHE E 374 | 1.74A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE E 347VAL E 401ILE E 402PHE E 429ALA E 397 | 1.36A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | PHE A 347VAL A 401ILE A 402PHE A 429ALA A 397 | 1.36A | None | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6yor | SPIKE GLYCOPROTEIN (SARS-CoV-2) | 5 / 12 | VAL A 401ILE A 402PHE A 429LEU A 425ALA A 397 | 1.46A | 22.73 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_2 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywk | NSP3 MACRODOMAIN (SARS-CoV-2) | 4 / 4 | VAL A 144ARG A 141HIS A 138PHE A 168 | 1.34A | 20.71 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_2 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywk | NSP3 MACRODOMAIN (SARS-CoV-2) | 4 / 4 | VAL C 144ARG C 141HIS C 138PHE C 168 | 1.33A | 20.71 | NoneNoneEDO C 208 ( 4.9A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_2 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywl | NSP3 MACRODOMAIN (SARS-CoV-2) | 4 / 4 | VAL C 144ARG C 141HIS C 138PHE C 168 | 1.33A | 20.71 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_2 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywl | NSP3 MACRODOMAIN (SARS-CoV-2) | 4 / 4 | VAL A 144ARG A 141HIS A 138PHE A 168 | 1.32A | 20.71 | NoneNoneEDO A 204 ( 4.0A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywm | NSP3 MACRODOMAIN (SARS-CoV-2) | 5 / 12 | VAL C 100ILE C 106PHE C 116ALA C 38SER C 128 | 1.78A | NoneNoneNoneMES C 201 (-3.5A)MES C 201 (-4.6A) | |||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_A_DP0A190_2 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 6ywm | NSP3 MACRODOMAIN (SARS-CoV-2) | 4 / 4 | VAL A 144ARG A 141HIS A 138PHE A 168 | 1.33A | 20.71 | NoneEDO A 206 (-4.2A)EDO A 205 (-3.9A)None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bqy | MAIN PROTEASE (SARS-CoV-2) | 5 / 12 | VAL A 125PHE A 291PHE A 3GLN A 127ARG A 298 | 1.76A | 19.87 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7btf | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 785PHE A 471PHE A 741LEU A 727GLN A 468 | 1.76A | 11.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7btf | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 317LEU A 282GLU A 254ARG A 285PHE A 287 | 1.65A | 11.57 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bv1 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726PHE A 471 | 1.71A | 11.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bv1 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726ALA A 43 | 1.76A | 11.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bv1 | NSP12 (SARS-CoV-2) | 5 / 12 | VAL A 785PHE A 471PHE A 741LEU A 727GLN A 468 | 1.78A | 11.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bv2 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726ALA A 43 | 1.70A | 11.67 | None | ||
| Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3APW_B_DP0B190_1 (ALPHA-1-ACIDGLYCOPROTEIN 2) | 7bv2 | NSP12 (SARS-CoV-2) | 5 / 12 | PHE A 745LEU A 723GLU A 744ARG A 726PHE A 471 | 1.72A | 11.67 | None |