Results

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	RMSD	Seq. Identity (%)	HETATM
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1ssk	NUCLEOCAPSID PROTEIN (SARSr-CoV)	3 / 3	THR A 143 THR A 144 PHE A 149	1.22A	13.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1uk3	3C-LIKE PROTEINASE (SARSr-CoV)	5 / 12	LEU A 262 THR A 225 THR A 224 ASN A 221 TYR A 209	1.77A	20.51	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1wnc	E2 GLYCOPROTEIN (SARSr-CoV)	5 / 12	ILE F1164 ASP F1165 ALA A 938 ALA A 940 ASN A 937	1.69A	15.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	1wnc	E2 GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 932 GLN F 939 ALA D1155 ALA F 940 ASN D1154	1.59A	13.85	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1x7q	HLA, A-11 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.79A	17.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	1z1j	3C-LIKE PROTEINASE (SARSr-CoV)	4 / 4	ASN B1221 LEU B1262 PHE B1219 TYR B1209	1.77A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	1zva	E2 GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP A 60 ASN A 54 PHE A 27	0.85A	13.87	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2ajf	ACE2 SPIKE PROTEIN (Homo sapiens; SARSr-CoV)	3 / 3	ASN B 33 LEU F 443 PHE B 28	1.07A	21.02	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ajf	SPIKE PROTEIN (SARSr-CoV)	5 / 12	ASP E 385 SER E 386 THR E 363 ALA E 422 TYR E 410	1.70A	19.70	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2cjr	NUCLEOCAPSID PROTEIN (SARS-COV TW1)	5 / 12	ILE A 321 TYR A 334 SER A 319 ALA B 312 ALA A 309	1.71A	12.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.62A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN S 427 PHE S 483 TYR S 494	1.31A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.67A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.67A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2dd8	IGG HEAVY CHAIN SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP S 392 THR H 70 THR H 68 TRP H 47 TYR S 491	1.65A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2fav	REPLICASE POLYPROTEIN 1AB (PP1AB) (ORF1AB) (SARSr-CoV)	5 / 12	SER C 30 ALA C 90 TYR C 153 ASN C 5 TYR C 10	1.78A	16.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2fe8	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN B 14 LEU B 65 PHE B 9	0.82A	19.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2fe8	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.80A	23.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2fyg	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	5 / 12	ASP A 64 ALA A 54 TYR A 126 ASN A 114 CYH A 103	1.76A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ga6	ORF1A POLYPROTEIN (SARSr-CoV)	3 / 3	ASP I 91 ASN G 85 PHE G 89	1.33A	17.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ga6	ORF1A POLYPROTEIN (SARSr-CoV)	5 / 12	ASP D 64 ALA D 54 TYR D 126 ASN D 114 CYH D 103	1.74A	17.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 54 TYR D 53 SER D 52 ALA C 430 ASN C 427	1.71A	21.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	3 / 3	THR D 134 THR D 135 PHE D 230	1.20A	19.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 54 TYR D 53 SER D 56 ALA C 430 ASN C 427	1.71A	21.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	5 / 12	SER D 163 THR D 229 THR D 134 ALA D 157 TYR D 103	1.62A	23.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2ghw	ANTI-SCFV ANTIBODY, 80R (Homo sapiens)	5 / 12	ASP B 202 SER B 154 THR B 134 THR B 135 TRP B 167	1.56A	23.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2ghw	ANTI-SCFV ANTIBODY, 80R SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	ASP B 182 TYR A 442 SER B 163 ASN A 457 TYR A 440	1.70A	19.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2h85	PUTATIVE ORF1AB POLYPROTEIN (SARSr-CoV)	3 / 3	ASN A 277 LEU A 254 PHE A 279	0.95A	21.05	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2k87	NSP3 OF REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASP A 61 ASN A 59 PHE A 54	1.46A	12.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2ofz	NUCLEOCAPSID PROTEIN (SARS-COV Tor2)	3 / 3	ASN A 155 PHE A 54 TYR A 112	1.32A	16.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	2og3	NUCLEOCAPSID PROTEIN (SARS-COV Tor2)	3 / 3	THR A 158 THR A 55 PHE A 111	0.91A	14.96	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2ozk	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN C 277 LEU C 254 PHE C 279	1.18A	21.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2pwx	3C-LIKE PROTEINASE (SARS-COV BJ01)	3 / 3	ASN A 221 PHE A 219 TYR A 209	1.24A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2pwx	3C-LIKE PROTEINASE (SARS-COV BJ01)	4 / 4	ASN A 221 LEU A 262 PHE A 219 TYR A 209	1.61A	20.26	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2q6g	POLYPEPTIDE CHAIN REPLICASE POLYPROTEIN 1AB (SARS-COV BJ01)	5 / 12	SER C 7 LEU A 86 THR A 175 TYR A 54 CYH A 44	1.80A	3.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN F 277 LEU F 254 PHE F 279	0.99A	21.51	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASP A 282 ASN B 163 PHE A 268	1.40A	21.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2rhb	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARSr-CoV)	3 / 3	ASN F 277 LEU F 254 PHE F 279	0.90A	21.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2w2g	NSP3 (SARSr)	3 / 3	ASN B 427 PHE B 414 TYR B 487	1.43A	20.47	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	19.46	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.71A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyq	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.66A	20.71	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	19.46	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyq	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.59A	20.71	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyq	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	19.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyr	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.66A	20.28	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.64A	19.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	20.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	2xyr	NSP10 PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.59A	20.28	None None None None ZN B1132 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	NSP10 (SARSr-CoV)	5 / 12	ASP B 64 ALA B 54 TYR B 126 ASN B 114 CYH B 103	1.76A	16.45	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.67A	20.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	2xyr	PUTATIVE 2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.70A	19.87	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3bgf	F26G19 FAB SPIKE PROTEIN S1 (Mus musculus; SARSr-CoV)	5 / 12	ILE H 97 ASP S 392 ALA L 51 ALA L 50 TYR S 491	1.70A	16.99	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3bgf	SPIKE PROTEIN S1 (SARSr-CoV)	5 / 12	TYR A 436 ASN A 437 THR A 433 THR A 431 TYR S 338	1.78A	16.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3bgf	F26G19 FAB SPIKE PROTEIN S1 (Mus musculus; SARSr-CoV)	3 / 3	THR B 31 THR B 30 PHE A 360	1.10A	18.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0g	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.07A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0g	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.75A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0h	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.77A	19.49	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3d0h	ACE2 SPIKE GLYCOPROTEIN (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN B 33 LEU F 443 PHE B 28	0.96A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3d0i	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.74A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3e91	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	THR A 226 THR A 225 PHE A 223	1.29A	20.78	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3e91	3C-LIKE PROTEINASE (SARSr-CoV)	5 / 12	ILE B 200 TRP B 207 ALA B 285 ALA B 284 TYR B 239	1.64A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3e9s	NSP3 (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.95A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3f9g	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	THR A 226 THR A 225 PHE A 223	1.24A	22.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.73A	18.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.70A	17.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.67A	17.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3i6k	HLA, A-2 (Homo sapiens)	5 / 12	ASP A 119 TYR A 118 THR A 80 ALA A 139 ASN A 86	1.71A	19.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3mj5	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.89A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3mj5	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.86A	23.13	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	20.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3r24	2'-O-METHYL TRANSFERASE NSP10 AND NSP11 (SARSr-CoV)	5 / 12	ASP A 102 THR A 82 ALA A 83 ALA A 107 CYH B 77	1.61A	20.91	None None None None ZN B 998 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.68A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.69A	20.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.66A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	3r24	2'-O-METHYL TRANSFERASE (SARSr-CoV)	5 / 12	TYR A 228 TRP A 231 THR A 195 ALA A 10 TRP A 190	1.73A	20.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sck	ACE2 SPIKE GLYCOPROTEIN (Paguma larvata; Homo sapiens; SARSr-CoV)	5 / 12	ASP A 355 TYR A 41 THR E 433 ALA A 65 ASN A 49	1.70A	22.48	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3sck	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP F 385 SER F 386 THR F 363 ALA F 422 TYR F 410	1.73A	20.19	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sck	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	5 / 12	ASP A 225 THR A 519 TRP A 566 TYR A 207 ASN A 397	1.64A	22.48	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASP B 216 ASN B 578 PHE B 400	1.29A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.15A	22.85	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	3scl	ACE2 (Paguma larvata; Homo sapiens; SARSr-CoV)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.10A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	3sna	3C-LIKE PROTEINASE (SARSr-CoV)	3 / 3	ASN A 221 PHE A 219 TYR A 209	1.37A	22.57	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	3snc	3C-LIKE PROTEINASE PEPTIDE ALDEHYDE INHIBITOR AC-NSTSQ-H (SARSr-CoV)	5 / 12	ASP A 187 SER H 4 GLN A 189 ALA A 46 TYR A 54	1.73A	21.47	None ECC H 5 ( 4.9A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	4m0w	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.92A	22.43	None GOL A 405 (-4.2A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4m0w	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.91A	23.36	None GOL A 405 (-4.2A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	4ow0	PAPAIN-LIKE PROTEASE (SARS-COV Urbani)	4 / 4	ASN A 14 LEU A 88 PHE A 56 TYR A 36	1.78A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4rna	PAPAIN-LIKE PROTEASE (Human betacoronavirus 2c EMC/2012)	3 / 3	ASN A 114 LEU A 170 PHE A 269	1.16A	24.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	4wme	MERS-COV 3CL PROTEASE (MERS-CoV)	3 / 3	ASN B 226 LEU B 272 PHE D 106	1.45A	24.24	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.42A	20.78	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.45A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 499 LEU D 468 PHE D 445 TYR D 446	1.45A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	5 / 12	ASP C 29 SER C 33 THR C 12 ASN D 71 TYR D 69	1.80A	16.54	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ILE B 510 TYR B 498 ALA B 308 TRP B 385 CYH B 399	1.60A	21.93	None None None G3A B 606 ( 4.1A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.97A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ASP B 449 TYR B 447 THR B 516 ALA B 323 ASN B 521	1.74A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN B 334 TRP B 348 LEU B 321 PHE B 384	1.77A	21.12	SAH B 605 (-4.1A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8s	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	3 / 3	ASP B 390 ASN B 388 PHE B 431	1.32A	22.59	None G3A B 606 (-3.8A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN A 40 LEU B 18 PHE B 8	1.23A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN B 63 LEU B 7 PHE A 16	1.48A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.99A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN C 40 LEU D 18 PHE D 8	0.87A	14.53	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8t	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.35A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR B 368 THR B 378 ALA B 394 ALA B 396 ASN B 438	1.55A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.39A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	ASP B 449 TYR B 447 THR B 516 ALA B 323 ASN B 521	1.70A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 499 LEU D 468 PHE D 445 TYR D 446	1.59A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.15A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5c8u	GUANINE-N7 METHYLTRANSFERASE NSP10 (SARSr-CoV)	3 / 3	ASN D 63 LEU D 7 PHE C 16	1.15A	23.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	3 / 3	ASP D 432 ASN D 388 PHE D 401	0.98A	22.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	4 / 4	ASN D 334 TRP D 348 LEU D 321 PHE D 384	1.64A	21.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5c8u	GUANINE-N7 METHYLTRANSFERASE (SARSr-CoV)	5 / 12	TYR D 368 ALA D 394 ALA D 396 TYR D 370 ASN D 438	1.36A	20.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5e6j	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 4	ASN A 14 LEU A 88 PHE A 56 TYR A 36	1.55A	23.13	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5e6j	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN D 14 LEU D 65 PHE D 9	1.02A	22.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	TYR C 368 ALA C 394 ALA C 396 TYR C 370 ASN C 438	1.62A	20.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	4 / 4	ASN A 334 TRP A 348 LEU A 321 PHE A 384	1.77A	20.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	3 / 3	ASP C 211 ASN C 228 PHE C 233	1.22A	22.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	ASP O 64 ALA O 54 TYR O 126 ASN O 114 CYH O 103	1.74A	16.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	TYR A 368 ALA A 394 ALA A 396 TYR A 370 ASN A 438	1.61A	20.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	5 / 12	ILE A 510 TYR A 498 ALA A 308 TRP A 385 CYH A 399	1.49A	21.93	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5nfy	POLYPROTEIN 1AB (SARS-COV Frankfurt 1)	3 / 3	ASN M 40 LEU A 18 PHE A 8	1.16A	16.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5rfc	3C-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	THR A 226 THR A 225 PHE A 223	1.80A	15.72	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	4 / 4	ASN B 14 LEU B 88 PHE B 56 TYR B 36	1.75A	22.65	SO4 B 402 (-4.2A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN D 14 LEU D 65 PHE D 9	0.82A	22.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5tl6	REPLICASE POLYPROTEIN 1AB (SARSr-CoV)	3 / 3	ASN B 14 LEU B 65 PHE B 9	0.81A	23.37	SO4 B 402 (-4.2A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.65A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP A 757 SER A 712 THR A 856 ALA A1037 ALA A1038	1.80A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	4 / 4	ASN C 960 LEU C 978 PHE B 558 TYR C 723	1.71A	17.82	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5wrg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 385 SER C 386 THR C 363 ALA C 422 TYR C 410	1.71A	15.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x29	ENVELOPE SMALL MEMBRANE PROTEIN (SARSr-CoV)	5 / 12	TYR D 57 SER D 60 THR E 35 ALA E 40 ALA E 43	1.67A	11.34	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4r	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.00A	21.38	NAG A 503 ( 4.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x4r	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.03A	21.64	NAG A 503 ( 4.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x4r	S PROTEIN (MERS-CoV)	5 / 12	ILE A 245 ASP A 248 THR A 139 ALA A 309 ALA A 311	1.66A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x4r	S PROTEIN (MERS-CoV)	5 / 12	ASP A 83 TYR A 85 GLN A 37 ALA A 103 TYR A 293	1.64A	20.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.51A	23.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.49A	23.08	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.49A	20.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.63A	18.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x4s	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN A 189 PHE A 187 TYR A 197	1.29A	20.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASP A 727 ASN A 721 PHE C 305	1.21A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.59A	17.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x58	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN C 505 PHE C 501 TYR C 383	0.90A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x59	S PROTEIN (MERS-CoV)	5 / 12	THR B 798 THR B 797 ALA B1096 ALA B1099 TYR B 947	1.77A	15.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	THR B 71 THR B 75 PHE B 22	0.80A	18.66	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN A 960 LEU C 503 PHE C 529	1.16A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	3 / 3	ASN A 910 LEU A 898 PHE A 779	1.15A	17.83	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	ASP B1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.74A	18.66	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	TRP C 245 THR C 71 THR C 247 ALA C 237 ASN C 78	1.47A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5b	SPIKE GLYCOPROTEIN (SARS-COV BJ01)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.64A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5x5c	S PROTEIN (MERS-CoV)	3 / 3	ASN A 226 LEU A 179 PHE A 228	1.02A	16.88	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5x5c	S PROTEIN (MERS-CoV)	5 / 12	ASP C 83 TYR C 85 GLN C 37 ALA C 103 TYR C 293	1.64A	17.41	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5x5c	S PROTEIN (MERS-CoV)	3 / 3	ASN B 226 LEU B 179 PHE B 228	1.00A	15.27	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x5c	S PROTEIN (MERS-CoV)	4 / 4	ASN C1169 LEU C1155 PHE C 778 TYR C 777	1.53A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5x5f	S PROTEIN (MERS-CoV)	3 / 3	ASN C 619 PHE C 617 TYR C 642	1.34A	15.03	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	5x5f	S PROTEIN (MERS-CoV)	5 / 12	ILE C 245 ASP C 248 THR C 139 ALA C 309 ALA C 311	1.67A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	5xlr	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN C 189 PHE C 187 TYR C 197	1.10A	15.90	ASN C 189 ( 0.6A) PHE C 187 ( 1.3A) TYR C 197 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5xlr	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP C 376 ASN C 530 PHE C 527	1.23A	15.92	ASP C 376 ( 0.6A) ASN C 530 ( 0.6A) PHE C 527 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	5y3e	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 81 PHE A 56	1.10A	23.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5y3q	REPLICASE POLYPROTEIN 1A (SARSr-CoV)	3 / 3	ASN A 14 LEU A 65 PHE A 9	0.90A	22.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	5zvm	PAN-COV INHIBITORY PEPTIDE EK1 SPIKE GLYCOPROTEIN (SARSr-CoV; synthetic construct)	3 / 3	ASN B 907 LEU a 39 PHE B 909	0.91A	11.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN C 960 LEU A 504 PHE A 527	0.94A	18.39	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 23 TRP C 245 THR C 71 THR C 247 ALA C 237	1.74A	18.39	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C 23 TRP C 245 THR C 71 THR C 247 ALA C 237	1.65A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6acd	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER C1012 THR C 760 ALA C1004 ALA C1007 ASN C1005	1.63A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN B 721 LEU B 749 PHE B 741	0.99A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ILE B1000 THR A1009 ALA A1004 ALA A1002 ASN A 759	1.63A	17.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6acg	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	THR C 487 THR C 485 ALA C 430 TRP C 423 TYR C 494	1.73A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6acj	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP A1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.67A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASN A 427 PHE A 483 TYR A 494	0.97A	15.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6ack	ACE2 SPIKE GLYCOPROTEIN (Homo sapiens; SARSr-CoV)	5 / 12	TYR D 41 THR C 431 THR C 485 ALA C 430 TYR C 436	1.79A	21.57	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	ASP B 454 ASN A 158 PHE A 130	1.04A	15.84	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ack	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	THR B 71 THR B 75 PHE B 22	0.93A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	THR C1058 THR C1059 PHE C1085	1.30A	19.04	None None NAG C1308 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP B 245 THR B 75 THR B 247 ALA B 237 ASN B 78	1.53A	17.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.44A	16.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.42A	16.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ASP B1023 SER C1012 ALA C1004 ALA C1007 ASN C1005	1.70A	19.04	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.70A	17.60	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP C 245 THR C 75 THR C 247 ALA C 237 ASN C 78	1.43A	16.37	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crv	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER B1012 THR B 760 ALA B1004 ALA B1007 ASN B1005	1.75A	16.37	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crw	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	SER C1012 THR C 760 ALA C1004 ALA C1007 ASN C1005	1.62A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crw	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 189 PHE A 187 TYR A 197	1.05A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ASP C1023 SER A1012 ALA A1004 ALA A1007 ASN A1005	1.68A	18.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.48A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.58A	17.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.47A	15.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6crx	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	TRP A 245 THR A 75 THR A 247 ALA A 237 ASN A 78	1.50A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6crz	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 901 LEU A1031 PHE A1091	0.82A	17.40	NAG A1311 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6cs0	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	5 / 12	ILE C 674 THR A 848 ALA C 654 ALA C 633 TYR C 677	1.55A	17.17	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs0	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASN A 901 LEU A1031 PHE A1091	0.98A	16.01	NAG A1311 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6cs1	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	THR A 693 THR A1059 PHE A1079	0.82A	18.61	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs2	SPIKE GLYCOPROTEIN,FIBRITI N (SARSr-CoV)	3 / 3	ASP B 727 ASN B 721 PHE A 305	1.04A	16.01	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6cs2	ACE2 SPIKE GLYCOPROTEIN,FIBRITI N (Homo sapiens; SARSr-CoV)	5 / 12	ASP D 355 THR B 433 THR B 431 ALA B 430 TYR D 41	1.71A	21.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6iex	BETA-2-MICROGLOBULIN MHC CLASS I ANTIGEN (Homo sapiens)	5 / 12	SER B 52 THR A 240 ALA A 236 TYR B 26 TYR B 63	1.77A	12.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6jyt	HELICASE (SARSr-CoV)	3 / 3	ASN B 381 PHE B 422 TYR B 421	1.40A	20.97	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6jyt	HELICASE (SARSr-CoV)	3 / 3	THR B 550 THR B 549 PHE B 475	1.30A	21.81	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr-CoV)	3 / 3	ASP A 32 ASN A 102 PHE A 133	1.32A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr)	3 / 3	ASN B 9 LEU B 132 PHE B 24	1.33A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6jyt	HELICASE (SARSr-CoV)	5 / 12	ILE A 20 SER B 38 THR B 104 ALA B 108 ALA B 110	1.23A	21.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6jyt	HELICASE (SARSr)	3 / 3	ASN A 9 LEU A 132 PHE A 24	1.30A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6lxt	SPIKE PROTEIN S2 (SARS-CoV-2)	5 / 12	ASP B 936 SER B 940 THR A 941 ALA A 942 ASN A1187	1.68A	18.65	ZN B1301 (-2.4A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6lxt	SPIKE PROTEIN S2 (SARS-CoV-2)	3 / 3	ASN C 925 LEU B1200 PHE C 927	0.88A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6lzg	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.73A	18.48	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6lzg	ACE2 (Homo sapiens)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.12A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6lzg	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.66A	20.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6lzg	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.62A	20.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6lzg	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.77A	22.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6lzg	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.56A	20.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m0j	ACE2 (Homo sapiens)	3 / 3	ASN A 572 LEU A 529 PHE A 555	1.12A	22.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m0k	VIRAL PROTEASE (SARS-CoV-2)	3 / 3	THR A 226 THR A 225 PHE A 223	1.46A	20.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	4 / 4	ASN C 310 LEU C 427 PHE C 48 TYR C 129	1.39A	20.40	None None LEU C 707 (-4.7A) LEU C 707 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN C 54 LEU C 254 PHE C 312	0.82A	21.11	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m17	RECEPTOR BINDING DOMAIN (SARS-CoV-2)	5 / 12	ASP F 398 SER F 399 THR F 376 ALA F 435 TYR F 423	1.71A	21.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m17	RECEPTOR BINDING DOMAIN (SARS-CoV-2)	5 / 12	ASP F 442 SER F 438 ASN F 440 TRP F 436 ASN F 343	1.58A	19.70	None None None None NAG F1401 (-2.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m17	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN C 54 LEU C 254 PHE C 312	0.84A	21.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m17	RECEPTOR BINDING DOMAIN (SARS-CoV-2)	5 / 12	ASP F 442 SER F 438 ASN F 440 TRP F 436 ASN F 343	1.42A	19.70	None None None None NAG F1401 (-2.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m18	ACE2 (Homo sapiens)	5 / 12	TYR D 649 SER D 707 ALA B 714 ALA D 714 TYR B 633	1.44A	18.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m18	ACE2 (Homo sapiens)	5 / 12	TYR D 649 SER D 707 ALA B 714 ALA D 714 TYR B 633	1.49A	20.10	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASN B 572 LEU B 529 PHE B 555	0.96A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	3 / 3	ASN A 258 PHE A 255 TYR A 322	1.29A	20.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	5 / 12	SER D 502 THR D 125 THR D 129 ASN D 508 TYR D 180	1.76A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	5 / 12	ASP A 486 SER A 487 THR A 121 ALA A 590 TYR A 128	1.72A	20.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	SODIUM-DEPENDENT NEUTRAL AMINO ACID TRANSPORTER B(0)AT1 (Homo sapiens)	5 / 12	ASP A 486 SER A 487 THR A 121 ALA A 590 TYR A 128	1.79A	21.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	5 / 12	SER D 502 THR D 125 THR D 129 ASN D 508 TYR D 180	1.77A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASN B 572 LEU B 529 PHE B 555	1.05A	19.30	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m1d	ACE2 (Homo sapiens)	3 / 3	ASP B 67 ASN B 61 PHE B 40	1.28A	18.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m3m	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	SER A 80 THR A 136 ALA A 135 ALA A 139 TYR A 113	1.74A	16.45	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m3m	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN B 155 PHE B 54 TYR B 112	1.32A	16.45	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m3m	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR C 166 THR C 167 PHE C 172	1.02A	14.07	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	4 / 4	ASN A 416 LEU A 437 PHE A 422 TYR A 884	1.51A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.53A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	5 / 12	TYR A 149 THR A 123 ALA A 185 ASN A 215 TYR A 69	1.79A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 705 LEU A 630 PHE A 782	1.75A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	THR A 686 ALA A 690 ALA A 634 ASN A 691 CYH A 622	1.78A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 805 PHE A 753	1.48A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.18A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.52A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	5 / 12	THR A 680 TYR A 456 ASN A 459 TYR A 453 CYH A 395	1.47A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.28A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	5 / 12	THR A 680 TYR A 456 ASN A 459 TYR A 453 CYH A 395	1.51A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.14A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASP A 454 ASN A 459 PHE A 165	1.22A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.50A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	THR A 686 ALA A 690 ALA A 634 ASN A 691 CYH A 622	1.75A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.43A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 247 PHE A 793	0.90A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.11A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.48A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP8 (SARS-CoV-2)	3 / 3	ASP D 101 ASN D 108 PHE D 92	1.16A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.70A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU D 91 PHE C 49	1.72A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	THR A 686 ALA A 690 ALA A 634 ASN A 691 CYH A 622	1.72A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	1.12A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASP A 761 ASN A 691 PHE A 480	1.78A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 146 PHE A 793	1.70A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU A 544 PHE A 441	1.61A	11.63	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 172 PHE A 793	0.69A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 636 PHE A 348	1.73A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m71	NSP12 (SARS-CoV-2)	3 / 3	THR A 393 THR A 394 PHE A 396	1.21A	19.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	5 / 12	TYR A 149 THR A 123 ALA A 185 ASN A 215 TYR A 69	1.75A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.91A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 791 LEU A 131 PHE A 793	1.61A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 135 SER A 784 THR A 710 ALA A 706 TYR A 129	1.77A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 838 PHE A 422	1.53A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 636 PHE A 348	1.59A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 723 PHE A 753	1.17A	19.98	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	TYR A 149 THR A 123 ALA A 185 ASN A 215 TYR A 69	1.61A	20.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU C 13 PHE A 440	1.33A	10.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.13A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.80A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 79 PHE A 219 TYR A 217	1.77A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6m71	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU D 91 PHE C 49	1.56A	16.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 PHE A 422 TYR A 884	1.33A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 554 TYR A 453 TYR A 456	1.70A	19.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.44A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	5 / 12	TYR A 149 THR A 123 ALA A 185 ASN A 215 TYR A 69	1.64A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6m71	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.57A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6m71	NSP12 (SARS-CoV-2)	3 / 3	ASN A 713 PHE A 35 TYR A 32	1.52A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nb6	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	ASP C1023 SER B1012 ALA B1004 ALA B1007 ASN B1005	1.79A	18.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	3 / 3	THR A1098 THR A1099 PHE A1103	1.16A	18.77	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.56A	16.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.62A	16.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6nb7	SPIKE GLYCOPROTEIN (SARSr-CoV)	5 / 12	SER A1012 THR A 760 ALA A1004 ALA A1007 ASN A1005	1.54A	17.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6nur	NSP12 (SARSr-CoV)	3 / 3	THR A 393 THR A 394 PHE A 396	1.12A	19.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.03A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6nur	NSP12 (SARSr-CoV)	3 / 3	ASN A 705 LEU A 630 PHE A 471	0.90A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6nur	NSP12 (SARSr-CoV)	5 / 12	ASP A 390 ASN A 447 TYR A 453 TYR A 674 CYH A 669	1.64A	19.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	4 / 4	ASN A 168 LEU A 146 PHE A 793 TYR A 787	1.73A	20.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.76A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6nur	NSP12 (SARSr-CoV)	5 / 12	SER A 759 ALA A 634 ALA A 690 TYR A 619 CYH A 622	1.72A	18.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6nur	NSP12 (SARSr)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.91A	18.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C1041 SER A1030 ALA A1022 ALA A1025 ASN A1023	1.62A	16.69	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN B 801 LEU B 878 PHE B 817	0.82A	16.75	NAG B1309 (-1.8A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.53A	18.02	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASP A1139 ASN A1119 PHE A1103	1.42A	16.75	None None NAG A1311 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.48A	17.82	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR C 572 THR C 573 PHE A 43	1.16A	18.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C1041 SER A1030 ALA A1022 ALA A1025 ASN A1023	1.69A	18.15	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.42A	18.02	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	SER C1030 THR C 778 ALA C1022 ALA C1025 ASN C1023	1.60A	16.69	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 440 PHE A 497 TYR A 505	1.11A	16.69	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vsb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.78A	16.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vww	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASP A 129 ASN A 83 PHE A 123	0.91A	20.27	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C 796 THR B1077 THR B1076 ASN B1074 TYR B 707	1.58A	18.18	None None None NAG B1316 (-1.9A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ILE C 794 ASP C 796 THR B1077 ASN B1074 TYR B 707	1.51A	17.73	None None None NAG B1316 (-1.9A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	SER A1030 THR A 778 ALA A1022 ALA A1025 ASN A1023	1.63A	16.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.46A	18.18	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.47A	18.18	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR A 393 THR A 523 PHE A 329	1.10A	18.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B 442 SER B 438 TRP B 436 ALA B 435 TYR B 451	1.55A	18.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	TYR B 396 SER B 514 THR B 523 ALA B 522 TYR C 200	1.57A	16.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 928 LEU A 916 PHE A 797	1.07A	18.18	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN B 801 LEU B 878 PHE B 817	0.71A	16.64	NAG B1314 (-1.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASP C1139 ASN C1119 PHE C1121	1.44A	16.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vxx	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.60A	16.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 796 THR C1077 THR C1076 ASN C1074 TYR C 707	1.60A	18.18	None None None NAG C1315 (-1.9A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	TYR C 396 SER C 514 THR C 523 ALA C 522 TYR A 200	1.59A	16.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	SER C1030 THR C 778 ALA C1022 ALA C1025 ASN C1023	1.63A	16.71	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASP A1139 ASN A1119 PHE A1121	1.44A	16.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	SER C1030 THR C 778 ALA C1022 ALA C1025 ASN C1023	1.58A	17.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR A 393 THR A 523 PHE A 329	1.11A	18.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP B1041 SER C1030 ALA C1022 ALA C1025 ASN C1023	1.77A	18.12	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_C_0HKC2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 796 THR C1077 THR C1076 ASN C1074 TYR C 707	1.60A	18.18	None None None NAG C1315 (-1.9A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 801 LEU A 878 PHE A 817	0.72A	16.64	NAG A1314 (-1.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN B 928 LEU B 916 PHE B 797	1.06A	18.18	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vyb	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 936 SER A 940 THR A 723 THR A 724 ALA A 944	1.65A	16.64	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	THR B 165 THR B 166 PHE B 171	0.92A	15.17	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 154 PHE A 53 TYR A 111	1.36A	16.88	MES A 201 (-3.2A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	4 / 4	ASN B 77 LEU A 167 PHE A 53 TYR A 87	1.77A	15.65	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN D 77 LEU C 64 PHE C 53	1.13A	15.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN B 77 LEU A 64 PHE A 53	1.19A	15.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	5 / 12	SER D 79 THR D 135 ALA D 134 ALA D 138 TYR D 112	1.73A	16.88	ZN D 201 ( 4.1A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN C 154 PHE C 53 TYR C 111	1.36A	16.88	MES B 202 (-2.8A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN D 154 PHE D 53 TYR D 111	1.37A	16.88	MES C 204 (-3.2A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6vyo	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	ASN B 154 PHE B 53 TYR B 111	1.38A	16.88	MES A 203 (-3.1A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w01	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 278 LEU B 255 PHE B 280	0.91A	20.27	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w01	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN A 278 LEU A 255 PHE A 280	1.00A	21.22	PEG A 405 (-3.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w37	PROTEIN 7A (SARS-CoV-2)	3 / 3	THR A 12 THR A 13 PHE A 44	1.75A	8.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w37	PROTEIN 7A (SARS-CoV-2)	3 / 3	THR A 13 THR A 12 PHE A 44	1.51A	8.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w37	PROTEIN 7A (SARS-CoV-2)	3 / 3	THR A 13 THR A 42 PHE A 39	1.50A	8.38	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.53A	14.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.58A	14.35	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w41	CR3022 FAB LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 72 THR L 20 PHE L 62	1.58A	16.24	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.76A	16.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.61A	16.42	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.56A	16.42	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	3 / 3	ASN C 370 LEU C 387 PHE C 374	1.72A	16.42	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	5 / 12	ASP C 442 SER C 438 TRP C 436 ALA C 435 TYR C 451	1.76A	14.76	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w41	CR3022 FAB HEAVY CHAIN CR3022 FAB LIGHT CHAIN (Homo sapiens)	5 / 12	SER H 99 THR L 53 ALA L 51 ALA L 34 ASN L 31	1.31A	14.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w41	SPIKE PROTEIN S1 (SARS-CoV-2)	3 / 3	THR C 523 THR C 393 PHE C 515	1.47A	14.76	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w4b	NSP9 (SARS-CoV-2)	5 / 12	ASP B 48 SER B 47 THR B 25 ALA B 23 ALA B 17	1.79A	14.43	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w4h	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A	20.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w4h	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.75A	19.95	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w4h	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.72A	20.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w4h	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A	20.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w4h	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.72A	20.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w61	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	5 / 12	ASP A6900 THR A6880 ALA A6881 ALA A6905 CYH B4330	1.71A		None None None None ZN B4403 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w61	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	5 / 12	ASP A6900 THR A6880 ALA A6881 ALA A6905 CYH B4330	1.64A		None None None None ZN B4403 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w61	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	3 / 3	ASN B4293 LEU A6834 PHE B4321	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.65A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w61	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.75A	16.90	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.70A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP10 (SARS-CoV-2)	5 / 12	ASP B4317 ALA B4307 TYR B4379 ASN B4367 CYH B4356	1.79A	17.00	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.67A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.66A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.72A	19.31	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP10 NSP16 (SARS-CoV-2)	3 / 3	ASN D4293 LEU C6834 PHE D4321	1.74A	13.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.67A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.73A	16.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.67A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.72A	15.80	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.68A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.71A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.76A	16.09	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP10 NSP16 (SARS-CoV-2)	3 / 3	ASN B4293 LEU A6834 PHE B4321	1.69A	13.92	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.66A	15.80	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A	19.31	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.73A	16.09	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w75	NSP10 NSP16 (SARS-CoV-2)	5 / 12	ASP C6900 THR C6880 ALA C6881 ALA C6905 CYH D4330	1.61A	16.90	None None None None ZN D4401 ( 2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.69A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.69A	19.31	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w75	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A	15.80	None None None None FMT A7111 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 64 PHE B 55	1.25A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 64 PHE B 8	1.04A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 64 PHE C 8	1.14A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ASP B 134 ALA B 153 ALA B 149 TYR B 72 TYR B 71	1.77A	17.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 64 PHE C 8	0.93A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ILE C 14 THR C 90 ALA C 145 ALA C 139 TYR C 56	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 PHE A 55 TYR A 35	1.61A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 64 PHE B 55	1.34A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 80 PHE C 55	1.43A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 87 PHE B 55	1.12A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 PHE C 55 TYR C 35	1.51A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	THR B 311 THR B 312 PHE B 216	1.78A	17.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	TYR B 273 THR B 168 ALA B 116 ALA B 114 CYH B 260	1.73A		None None None CL B 502 ( 3.8A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 80 PHE C 55	1.27A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 36 PHE A 8	1.43A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 8	0.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	TYR C 273 THR C 168 ALA C 116 ALA C 114 CYH C 260	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	THR C 311 THR C 312 PHE C 216	1.78A	17.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 8	0.90A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 80 PHE B 55	1.37A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 64 PHE C 55	1.32A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ASP A 134 ALA A 153 ALA A 149 TYR A 72 TYR A 71	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ASP C 134 ALA C 153 ALA C 149 TYR C 72 TYR C 71	1.77A	17.94	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 55	1.21A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ASP C 134 ALA C 153 ALA C 149 TYR C 72 TYR C 71	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 87 PHE B 55	1.44A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ASP B 134 ALA B 153 ALA B 149 TYR B 72 TYR B 71	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 36 PHE B 8	1.30A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 64 PHE B 8	0.86A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 PHE B 55 TYR B 35	1.43A	21.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 36 PHE B 8	1.35A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	SER C 170 THR C 115 THR C 119 ALA C 116 CYH C 155	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	SER A 170 THR A 115 THR A 119 ALA A 116 CYH A 155	1.65A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN B 13 LEU B 80 PHE B 55	1.08A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	SER C 170 THR C 115 THR C 119 ALA C 116 CYH C 155	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN C 13 LEU C 64 PHE C 55	1.28A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 55	1.28A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	ILE A 14 THR A 90 ALA A 145 ALA A 139 TYR A 56	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6w9c	PAPAIN-LIKE PROTEINASE (SARS-CoV-2)	5 / 12	SER B 170 THR B 115 THR B 119 ALA B 116 CYH B 155	1.80A		None CL B 502 ( 4.9A) None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wcf	NSP3 (SARS-CoV-2)	3 / 3	ASN A 150 LEU A 12 PHE A 6	1.53A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP A 288 ASN A 354 PHE A 307	1.78A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP D 288 ASN D 285 PHE D 274	1.58A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN B 285 LEU B 291 PHE A 314	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP C 288 ASN C 285 PHE C 274	1.56A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP F 288 ASN F 354 PHE F 307	1.79A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP B 288 ASN B 285 PHE B 274	1.58A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP F 288 ASN F 285 PHE F 274	1.58A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP A 288 ASN A 285 PHE A 274	1.55A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP E 288 ASN E 285 PHE E 274	1.59A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASP C 288 ASN C 354 PHE C 307	1.77A	18.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN F 285 LEU F 291 PHE E 314	1.58A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR C 263 THR C 296 PHE D 315	1.51A	15.30	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wji	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	ILE B 320 TYR B 333 SER B 318 ALA A 311 ALA B 308	1.77A		None None None CL B 401 ( 3.7A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.66A		FMT A7107 (-3.7A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A		FMT A7107 (-3.7A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	5 / 12	ASP C6900 THR C6880 ALA C6881 ALA C6905 CYH D4330	1.65A		None None None None ZN D4401 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TRP C7029 THR C6993 ALA C7002 ALA C6990 CYH C6823	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.65A		FMT A7107 (-3.7A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.76A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.74A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	NSP10 (SARS-CoV-2)	5 / 12	ASP B4317 ALA B4307 TYR B4379 ASN B4367 CYH B4356	1.78A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	3 / 3	ASN B4293 LEU A6834 PHE B4321	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.71A		FMT A7107 (-3.7A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wjt	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A		None None None None FMT A7105 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR A 165 THR A 166 PHE A 171	1.25A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR C 166 THR C 165 PHE C 171	1.67A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	SER C 79 THR C 135 ALA C 134 ALA C 138 TYR C 112	1.73A		ZN C 201 (-3.5A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	SER D 79 THR D 135 ALA D 134 ALA D 138 TYR D 112	1.69A		ZN D 202 ( 4.1A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR B 165 THR B 166 PHE B 171	1.24A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	SER A 79 THR A 135 ALA A 134 ALA A 138 TYR A 112	1.75A		ZN A 201 (-3.3A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR C 165 THR C 166 PHE C 171	1.25A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN C 154 PHE C 53 TYR C 111	1.52A	17.50	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN D 154 PHE D 53 TYR D 111	1.31A	17.50	MES D 201 (-3.8A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	THR D 165 THR D 166 PHE D 171	1.20A	14.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN B 77 LEU A 64 PHE A 53	1.38A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN B 77 LEU A 64 PHE A 53	1.20A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	5 / 12	SER B 79 THR B 135 ALA B 134 ALA B 138 TYR B 112	1.71A		ZN B 202 (-3.2A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN B 154 PHE B 53 TYR B 111	1.39A	17.50	MES B 201 (-3.2A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkp	NUCLEOCAPSID PROTEIN (SARS-CoV-2)	3 / 3	ASN D 77 LEU C 64 PHE C 53	1.28A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6883 PHE C6991	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP10 (SARS-CoV-2)	5 / 12	ASP B4317 ALA B4307 TYR B4379 ASN B4367 CYH B4356	1.78A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.70A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP10 NSP16 (SARS-CoV-2)	3 / 3	ASN B4293 LEU A6834 PHE B4321	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.71A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkq	NSP10 NSP16 (SARS-CoV-2)	5 / 12	ASP C6900 THR C6880 ALA C6881 ALA C6905 CYH D4330	1.61A		None None None None ZN D4401 ( 2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.76A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR C7026 TRP C7029 THR C6993 ALA C6808 TRP C6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wkq	NSP16 (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.74A		None None None None FMT A7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN C6853 LEU C6924 PHE C6991	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wkq	NSP16 (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASP A 129 ASN A 83 PHE A 123	0.97A	20.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASP B 129 ASN B 83 PHE B 123	0.94A	20.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 278 LEU B 255 PHE B 280	1.13A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 12 LEU B 43 PHE B 16	1.53A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 140 LEU B 190 PHE B 124	1.59A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN A 278 LEU A 255 PHE A 280	0.99A	20.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN A 140 LEU A 190 PHE A 124	1.61A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN A 278 LEU A 255 PHE A 280	1.12A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 278 LEU B 249 PHE B 280	1.70A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN A 12 LEU A 43 PHE A 16	1.53A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASN B 278 LEU B 255 PHE B 280	0.97A	20.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASP A 324 ASN A 74 PHE A 123	1.45A	20.59	None EDO A 406 (-4.5A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wlc	URIDYLATE-SPECIFIC ENDORIBONUCLEASE (SARS-CoV-2)	3 / 3	ASP B 324 ASN B 74 PHE B 123	1.46A	20.59	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wq3	2'-O-METHYLTRANSFERA SE NSP10 (SARS-CoV-2)	5 / 12	ASP A6900 THR A6880 ALA A6881 ALA A6905 CYH B4330	1.63A		None None None None ZN B4401 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wq3	NSP10 (SARS-CoV-2)	3 / 3	ASN B4358 LEU B4284 PHE B4363	1.36A		SO4 A7107 (-4.0A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6924 PHE A6991	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	3 / 3	ASN A6853 LEU A6883 PHE A6991	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wq3	2'-O-METHYLTRANSFERA SE (SARS-CoV-2)	5 / 12	TYR A7026 TRP A7029 THR A6993 ALA A6808 TRP A6988	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wqd	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU C 60 PHE C 49	1.63A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wqd	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU D 91 PHE C 49	1.65A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	5 / 12	ASP A 134 ALA A 153 ALA A 149 TYR A 72 TYR A 71	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 PHE A 55 TYR A 35	1.59A	21.99	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	5 / 12	SER A 170 THR A 115 THR A 119 ALA A 116 CYH A 155	1.69A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 36 PHE A 8	1.43A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	5 / 12	SER A 170 THR A 115 THR A 119 ALA A 116 CYH A 155	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 8	0.89A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 8	0.88A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 55	1.22A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	THR A 311 THR A 312 PHE A 216	1.79A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	5 / 12	ASP A 134 ALA A 153 ALA A 149 TYR A 72 TYR A 71	1.79A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	3 / 3	ASN A 13 LEU A 64 PHE A 55	1.24A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6wrh	PEPTIDASE C16 (SARS-CoV-2)	5 / 12	ILE A 300 ASP A 302 SER A 262 ALA A 114 CYH A 260	1.62A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6wrh	NSP3 (SARS-CoV-2)	3 / 3	ASN A 308 LEU A 234 PHE A 241	0.93A	21.32	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xdc	PROTEIN 3A (SARS-CoV-2)	3 / 3	ASN A 82 LEU B 53 PHE A 87	1.07A	21.29	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xdc	PROTEIN 3A (SARS-CoV-2)	3 / 3	ASN B 82 LEU A 53 PHE B 87	1.14A	21.29	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xdc	PROTEIN 3A (SARS-CoV-2)	3 / 3	ASN A 82 LEU B 53 PHE A 56	1.30A	21.29	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xdc	PROTEIN 3A (SARS-CoV-2)	3 / 3	ASN B 82 LEU A 53 PHE B 56	1.37A	21.29	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xez	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.88A	17.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6xez	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 247 PHE A 793	1.05A	17.36	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6xez	NSP13 (SARS-CoV-2)	3 / 3	ASN F 381 PHE F 422 TYR F 421	1.47A	21.13	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yb7	REPLICASE POLYPROTEIN 1AB (SARS-CoV-2)	3 / 3	THR A 196 THR A 198 PHE A 134	1.64A	15.72	DMS A 404 (-4.8A) DMS A 404 (-3.8A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yhu	REPLICASE POLYPROTEIN 1A (SARS-CoV-2)	3 / 3	ASP B 101 ASN B 108 PHE B 92	1.57A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yi3	NUCLEOPROTEIN (SARS-CoV-2)	3 / 3	THR A 125 THR A 126 PHE A 131	1.01A	13.56	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR E 523 THR E 393 PHE E 515	1.68A	17.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN E 388 LEU E 335 PHE E 392	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.65A		None None DMS A 901 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.58A		None None DMS A 901 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	LIGHT CHAIN (Homo sapiens)	3 / 3	THR C 78 THR C 20 PHE C 68	1.71A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.78A		None None DMS A 901 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.72A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.63A		None None DMS E 901 ( 3.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN E 388 LEU E 335 PHE E 392	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.75A	17.14	None None DMS A 901 (-3.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.77A		None None DMS E 901 ( 3.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.75A	17.14	None None DMS E 901 ( 3.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yla	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.57A		None None DMS E 901 ( 3.9A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.61A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN E 388 LEU E 335 PHE E 392	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.74A	17.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ym0	LIGHT CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.71A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR E 523 THR E 393 PHE E 515	1.67A	17.14	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	6ym0	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.65A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ynq	REPLICASE POLYPROTEIN 1AB (SARS-CoV-2)	3 / 3	THR A 26 THR A 25 PHE A 66	1.79A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ynq	REPLICASE POLYPROTEIN 1AB (SARS-CoV-2)	3 / 3	THR A 24 THR A 25 PHE A 66	1.62A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6ynq	REPLICASE POLYPROTEIN 1AB (SARS-CoV-2)	3 / 3	THR A 25 THR A 26 PHE A 66	1.50A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN E 388 LEU E 335 PHE E 392	1.73A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.74A	18.72	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.57A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.56A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	IGG L CHAIN (Homo sapiens)	3 / 3	THR L 78 THR L 20 PHE L 68	1.72A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.80A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 388 LEU A 335 PHE A 392	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	IGG L CHAIN (Homo sapiens)	3 / 3	THR C 78 THR C 20 PHE C 68	1.72A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN A 388 LEU A 335 PHE A 392	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR A 523 THR A 393 PHE A 515	1.68A	18.72	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.75A	18.72	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	THR E 523 THR E 393 PHE E 515	1.68A	18.72	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP A 442 SER A 438 TRP A 436 ALA A 435 TYR A 451	1.63A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	5 / 12	ASP E 442 SER E 438 TRP E 436 ALA E 435 TYR E 451	1.62A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6yor	SPIKE GLYCOPROTEIN (SARS-CoV-2)	3 / 3	ASN E 388 LEU E 335 PHE E 392	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	6ywk	NSP3 MACRODOMAIN (SARS-CoV-2)	3 / 3	ASN C 150 LEU C 12 PHE C 6	1.51A		EDO C 204 ( 4.5A) None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6ywl	NSP3 MACRODOMAIN (SARS-CoV-2)	3 / 3	ASN B 59 LEU E 164 PHE E 156	1.27A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6zsl	SARS-COV-2 HELICASE NSP13 (SARS-CoV-2)	3 / 3	ASN A 9 LEU A 130 PHE A 24	1.33A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6zsl	SARS-COV-2 HELICASE NSP13 (SARS-CoV-2)	3 / 3	ASN B 489 LEU B 526 PHE B 546	0.99A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6zsl	SARS-COV-2 HELICASE NSP13 (SARS-CoV-2)	3 / 3	ASN A 489 LEU A 526 PHE A 546	0.94A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	6zsl	SARS-COV-2 HELICASE NSP13 (SARS-CoV-2)	3 / 3	ASN A 9 LEU A 132 PHE A 24	1.34A	23.06	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bqy	MAIN PROTEASE (SARS-CoV-2)	3 / 3	THR A 226 THR A 225 PHE A 223	1.66A	20.55	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 657 LEU A 372 PHE A 528	1.35A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 247 PHE A 793	1.44A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.48A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7btf	NSP12 (SARS-CoV-2)	3 / 3	THR A 393 THR A 394 PHE A 396	1.13A	19.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASP A 761 ASN A 691 PHE A 480	1.78A	17.91	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.09A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.09A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 713 PHE A 35 TYR A 32	1.48A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 636 PHE A 694	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 805 PHE A 753	1.50A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 79 PHE A 219 TYR A 217	1.71A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 791 LEU A 131 PHE A 793	1.60A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.90A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 448 TYR A 453 TYR A 456	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 146 PHE A 793	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.44A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU D 91 PHE C 49	1.66A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.20A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 39 LEU A 708 PHE A 35	1.25A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 247 PHE A 793	0.95A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	1.02A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7btf	NSP12 NSP8 (SARS-CoV-2)	3 / 3	THR B 89 THR B 93 PHE A 340	1.67A	15.73	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP8 (SARS-CoV-2)	3 / 3	ASP D 134 ASN D 140 PHE D 147	1.58A	18.20	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 723 PHE A 753	1.16A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.62A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.54A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 695 LEU A 749 PHE A 480	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.47A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN A 552 LEU C 35 PHE A 440	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 172 PHE A 793	0.80A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7btf	NSP12 (SARS-CoV-2)	3 / 3	THR A 929 THR A 926 PHE A 594	1.42A	19.90	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.22A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.53A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.58A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7btf	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU A 544 PHE A 441	1.65A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 636 PHE A 348	1.62A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.35A	18.33	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7btf	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 554 TYR A 453 TYR A 456	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU C 60 PHE C 49	1.64A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7btf	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 636 PHE A 348	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7buy	VIRUS MAIN PROTEASE (SARS-CoV-2)	3 / 3	ASN A 221 LEU A 262 PHE A 219	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASP A 454 ASN A 459 PHE A 165	1.29A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.58A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP7 NSP8 (SARS-CoV-2)	5 / 12	ILE D 120 SER C 54 THR C 9 ALA C 48 ASN D 100	1.78A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 247 PHE A 793	0.95A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 723 PHE A 753	1.14A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.28A	18.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bv1	NSP12 NSP8 (SARS-CoV-2)	3 / 3	THR B 89 THR B 93 PHE A 340	1.73A	16.86	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.15A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP7 NSP8 (SARS-CoV-2)	3 / 3	ASN D 104 LEU D 91 PHE C 49	1.64A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.54A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	1.14A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.51A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 135 SER A 784 THR A 710 ALA A 706 TYR A 129	1.71A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 247 PHE A 793	1.49A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.18A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.51A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.60A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 135 SER A 784 THR A 710 ALA A 706 TYR A 129	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.67A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN A 552 LEU C 35 PHE A 440	1.49A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.59A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 791 LEU A 131 PHE A 793	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 805 PHE A 753	1.54A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 554 TYR A 453 TYR A 456	1.64A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	THR A 393 THR A 394 PHE A 396	1.07A	19.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 554 TYR A 453 TYR A 456	1.62A	19.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU C 13 PHE A 440	1.37A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 636 PHE A 694	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.52A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U14_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	THR A 686 ALA A 690 ALA A 634 ASN A 691 CYH A 622	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN A 552 LEU C 35 PHE A 440	1.59A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU A 544 PHE A 441	1.76A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 705 LEU A 630 PHE A 471	0.95A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.16A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 657 LEU A 372 PHE A 528	1.47A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 135 SER A 784 THR A 710 ALA A 706 TYR A 129	1.72A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.18A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP8 (SARS-CoV-2)	3 / 3	ASN B 140 PHE B 147 TYR B 149	1.66A	19.62	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv1	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.79A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 705 LEU A 630 PHE A 471	1.02A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 172 PHE A 793	0.90A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.95A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv1	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.62A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	SER A 343 ALA A 656 ALA A 660 TYR A 653 ASN A 657	1.73A	19.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 623 ALA A 449 ALA A 554 TYR A 453 TYR A 456	1.68A		POP A1003 ( 3.5A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.15A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.53A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 247 PHE A 793	1.48A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 791 LEU A 131 PHE A 793	1.58A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	THR A 393 THR A 394 PHE A 396	1.16A	19.52	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 215 PHE A 192 TYR A 237	1.39A	18.40	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_A_0HKA2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	THR A 680 TYR A 456 ASN A 459 TYR A 453 CYH A 395	1.57A		F86 P 102 ( 4.9A) None None None None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 657 LEU A 372 PHE A 528	1.39A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 125 TYR A 728 TYR A 732	1.74A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 705 LEU A 630 PHE A 471	0.91A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 723 PHE A 753	1.13A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_A_0HKA2001_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	SER A 759 ALA A 634 ALA A 690 TYR A 619 CYH A 622	1.79A		U P 20 ( 2.8A) None None None F86 P 102 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 126 THR A 189 ALA A 185 TYR A 217 ASN A 215	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 172 PHE A 793	0.76A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASP A 608 ASN A 611 PHE A 766	1.76A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.51A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	0.94A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 314 LEU A 251 PHE A 275	1.10A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 348	1.52A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.18A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 469 PHE A 782	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.64A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_B_0HKB1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASP A 454 ASN A 459 PHE A 165	1.28A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 168 LEU A 460 PHE A 793	1.18A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	SER A 343 ALA A 656 ALA A 660 TYR A 653 ASN A 657	1.68A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 705 LEU A 630 PHE A 471	0.89A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU C 13 PHE A 440	1.39A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4U15_B_0HKB1201_1 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3,LYSOZYME,MUSCARIN IC ACETYLCHOLINE RECEPTOR M3)	7bv2	NSP12 (SARS-CoV-2)	5 / 12	ASP A 465 THR A 206 ALA A 34 TYR A 728 TYR A 732	1.42A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN A 552 LEU C 35 PHE A 440	1.55A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 862 PHE A 422	1.66A		None U P 17 ( 4.9A) None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 636 PHE A 694	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 767 LEU A 805 PHE A 753	1.54A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN A 552 LEU C 35 PHE A 440	1.56A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 416 LEU A 437 PHE A 422	1.12A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU A 544 PHE A 441	1.77A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 628 LEU A 308 PHE A 694	1.75A		None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 (SARS-CoV-2)	3 / 3	ASN A 790 LEU A 247 PHE A 793	0.88A	17.75	None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DSG_A_0HKA1201_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M4,ENDOLYSIN,ENDOLYS IN,MUSCARINIC ACETYLCHOLINE RECEPTOR M4)	7bv2	NSP12 NSP7 (SARS-CoV-2)	3 / 3	ASN C 37 LEU C 55 PHE A 440	1.31A		None