Ligand ID: 30Z


Drugbank ID:
DB00179
(Masoprocol)


Indication:
Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).

Get human targets for 30Z in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '30Z'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.36A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
LEU B  45
ALA B  30
LEU B  29
SER B  13
1.37A16.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU F 930
ALA F 926
LEU F 927
SER F 924
THR F 922
1.37A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		1wyy E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU A 930
ALA A 926
LEU A 927
SER A 924
THR A 922
1.75A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU K  30
ALA K  26
LEU K  27
SER K  24
THR K  22
1.65A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		4 / 6
GLY B 241
ASN B 240
LEU C 351
GLU B 246
1.13A20.70
GOL  B1001 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
PRO E 470
ASN E 473
LEU E 472
GLU A  75
1.45A19.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU C 930
ALA C 926
LEU C 927
SER C 924
THR C 922
1.66A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		2bez SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU C 930
ALA C 926
LEU C 927
SER C 924
THR C 922
1.73A15.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2bx4 3C-LIKE PROTEINASE
(SARS-COV
Sin2774)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.37A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 6
LYS G 262
THR G 264
ALA H 314
SER H 319
1.21A21.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H 123
GLY H 139
LEU H 138
GLU H 212
1.46A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
LEU C  81
ALA C  69
LEU C  59
SER C  61
1.28A21.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
PRO D 107
GLY D 109
LEU D 112
ASN D 114
1.42A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 6
GLY A  71
ASN A  69
LEU A  66
ASN A  69
1.28A20.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
PRO E 324
GLY E 326
ASN E 330
LEU E 355
1.04A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		2kqv NSP3
(SARSr-CoV)		5 / 7
LEU A 105
THR A   6
ALA A 109
LEU A  74
THR A  83
1.74A24.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU A 263
THR A 285
ALA A 283
LEU A 200
1.27A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LYS C 109
THR C  98
ALA C 108
SER C 114
1.34A18.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
LEU B 205
THR B 224
ALA B 266
LEU B 268
1.36A18.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		2w2g NSP3
(SARSr-CoV)		4 / 6
PRO A 630
ASN A 597
LEU A 627
GLU A 524
1.14A20.49
None
SO4  A1653 (-4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
LEU A  85
THR A 110
ALA A 107
LEU A  89
1.36A23.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3atw 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.36A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
LYS B  68
LEU B  39
ALA B  65
SER B  44
1.12A15.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.38A17.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.37A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
LEU A  85
THR A 110
ALA A 107
LEU A  89
1.36A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
LYS A  68
LEU A  39
ALA A  65
SER A  44
1.07A15.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		4m0w UBIQUITIN
(Bos
taurus)		4 / 6
LYS B  48
LEU B  50
ALA B  46
LEU B  67
1.35A16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		4 / 6
LEU A  81
ALA A  69
LEU A  59
SER A  61
1.37A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		4 / 6
LEU A 113
ALA A 115
LEU A 104
SER A 103
1.21A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
LEU D 109
THR D 122
ALA D 119
LEU D 117
1.19A16.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		5c8t GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 6
PRO C   8
ASN C  40
LEU D  27
GLU D   2
1.27A20.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
LEU D 109
THR D 122
ALA D 119
LEU D 117
1.18A16.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 6
LEU A 109
THR A 122
ALA A 119
LEU A 117
1.26A14.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.63A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.63A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.43A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.61A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A  87
THR A  25
LEU A  89
THR A  21
1.69A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.40A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.68A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.59A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
LEU B  81
ALA B  69
LEU B  59
SER B  61
1.19A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5x4r S PROTEIN
(MERS-CoV)		4 / 6
LYS A 308
THR A 139
ALA A 138
SER A 135
1.28A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		5x4r S PROTEIN
(MERS-CoV)		4 / 6
PRO A 196
GLY A 198
ASN A 199
GLU A 188
1.43A22.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		5x59 S PROTEIN
(MERS-CoV)		4 / 6
PRO B 196
GLY B 198
ASN B 199
GLU B 188
1.45A11.66
None
None
None
NAG  B1410 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 7
LEU C 745
THR B 991
LEU C 986
SER C 985
THR C 988
1.56A8.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
THR B 669
ALA B 671
LEU B 673
SER B 660
1.10A8.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU A 636
ALA A 595
LEU A 597
SER A 582
0.86A8.59
LEU  A 636 ( 0.6A)
ALA  A 595 ( 0.0A)
LEU  A 597 ( 0.6A)
SER  A 582 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU A 636
ALA A 595
LEU A 597
SER A 582
0.75A8.59
LEU  A 636 ( 0.6A)
ALA  A 595 ( 0.0A)
LEU  A 597 ( 0.6A)
SER  A 582 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN C 721
LEU C 735
ASN C 733
GLU C 730
1.11A11.83
ASN  C 721 ( 0.6A)
LEU  C 735 ( 0.6A)
ASN  C 733 ( 0.6A)
GLU  C 730 ( 0.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU B 930
ALA B 926
LEU B 927
SER B 924
THR B 922
1.74A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN C 721
LEU C 735
ASN C 733
GLU C 730
1.15A11.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
LEU A 636
ALA A 595
LEU A 597
SER A 582
0.77A8.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU A 636
ALA A 595
LEU A 597
SER A 582
0.87A8.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 721
LEU A 735
ASN A 733
GLU A 730
1.30A11.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
LEU B 636
ALA B 595
LEU B 597
SER B 582
0.75A8.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
LEU B 636
ALA B 595
LEU B 597
SER B 582
0.85A8.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 721
LEU A 735
ASN A 733
GLU A 730
1.25A11.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
LEU B 636
ALA B 595
LEU B 597
SER B 582
0.63A8.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
LEU B 636
ALA B 595
LEU B 597
SER B 582
0.67A8.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6lu7 MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.38A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.48A19.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.62A19.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.57A19.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.68A19.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.45A19.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.68A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.41A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.37A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.63A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.63A19.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m18 ACE2
(Homo
sapiens)		4 / 6
LYS D  68
LEU D  39
ALA D  65
SER D  44
1.06A11.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.38A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU D 205
THR D 224
ALA D 266
LEU D 268
1.40A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU B 268
THR B 225
ALA B 266
LEU B 271
1.58A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.60A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU D 205
THR D 225
ALA D 266
LEU D 208
1.60A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU C 268
THR C 225
ALA C 266
LEU C 271
1.61A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU B 205
THR B 225
ALA B 266
LEU B 208
1.63A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU B 268
THR B 225
ALA B 266
LEU B 271
1.56A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU D 205
THR D 224
ALA D 266
LEU D 268
1.35A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU D 268
THR D 225
ALA D 266
LEU D 271
1.61A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU B 205
THR B 224
ALA B 266
LEU B 268
1.38A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.58A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.35A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU B 205
THR B 224
ALA B 266
LEU B 268
1.34A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.62A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.42A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.46A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.65A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.62A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 576
ALA A 580
SER A 578
THR A 582
1.56A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 131
ALA A 130
LEU A 127
THR A 141
1.50A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 128
THR A 402
ALA A 400
LEU A 387
1.68A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
LEU A 372
THR A 538
ALA A 376
LEU A 371
1.63A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 248
ALA A 250
THR A 246
1.52A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 128
THR A 402
ALA A 400
SER A 397
1.60A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 246
ALA A 250
THR A 252
1.59A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 103
ALA B 125
LEU B  98
SER A 384
1.66A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 721
LEU B 735
ASN B 733
GLU B 730
1.34A11.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 7
LEU C 745
THR A 991
LEU C 986
SER C 985
THR C 988
1.66A8.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H 137
GLY H 153
LEU H 152
GLU H 226
1.47A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		4 / 6
LEU H 138
THR H 197
ALA H 151
SER H 141
1.06A19.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6nus NSP12
(SARSr-CoV)		5 / 7
LYS A 391
LEU A 389
THR A 394
LEU A 388
SER A 672
1.80A9.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU A 650
ALA A 609
LEU A 611
SER A 596
0.98A8.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
PRO B 600
GLY B 601
LEU B 296
ASN B 606
1.38A11.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU A 650
ALA A 609
LEU A 611
SER A 596
1.08A8.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6vw1 ACE2
(Homo
sapiens)		4 / 6
LYS B  68
LEU B  39
ALA B  65
SER B  44
1.27A15.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU B 650
ALA B 609
LEU B 611
SER B 596
0.93A8.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU B 650
ALA B 609
LEU B 611
SER B 596
0.83A8.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
GLY C 199
ASN C 196
ASN C 234
GLU B 465
1.18A11.02
None
None
NAG  C1303 (-1.9A)
NAG  C1303 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 6
PRO B 600
GLY B 601
ASN B 603
ASN B 606
GLU B 607
1.73A11.02
None
None
NAG  B1307 (-1.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU C 650
ALA C 609
LEU C 611
SER C 596
0.82A8.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU C 650
ALA C 609
LEU C 611
SER C 596
0.92A8.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L 135
ALA H 137
SER L 114
THR H 135
1.56A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
THR H 108
ALA H  88
SER H  85
THR H  87
1.45A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L 179
LEU L 181
SER L 182
THR L 129
1.78A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR H 100
LEU C 513
SER C 514
THR C 430
1.52A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H 123
GLY H 139
LEU H 138
GLU H 212
1.49A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 7
LEU L 136
THR L 172
LEU L 175
SER L 162
THR L 164
1.75A21.08
None
None
None
GOL  L 301 (-3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
LEU H 138
THR H 135
ALA H 136
SER H 128
1.57A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
LYS H  12
LEU H  82
SER H  85
THR H  87
1.72A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
THR L  72
LEU L  27
SER L  27
THR L  69
1.56A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L  11
THR L  74
ALA L  19
SER L  14
1.49A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 7
LEU C 513
THR C 376
SER C 383
THR H  31
1.58A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 7
LEU H 138
THR H 135
ALA H 136
SER H 128
1.56A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
THR A6908
ALA A6905
LEU A6887
1.36A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
LEU A6834
THR A6993
ALA A6843
THR A6846
1.63A19.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LYS A7075
LEU A7072
THR A6856
LEU A7078
1.75A19.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A7013
GLY A7011
LEU A7010
GLU A7015
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.59A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LYS A 137
ALA A 129
SER A 113
THR A 111
1.52A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.46A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.41A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
LEU A 122
THR A 146
LEU A  93
SER A  80
1.78A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
LEU B 153
THR B 149
LEU B 140
THR B 146
1.76A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w6y NSP3
(SARS-CoV-2)		4 / 7
LEU A 153
THR A 149
LEU A 140
THR A 146
1.77A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
LEU A 122
THR A 146
LEU A  93
SER A  80
1.79A23.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
THR A6908
ALA A6905
LEU A6887
1.38A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LEU C6883
THR C6908
ALA C6905
LEU C6887
1.36A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
LEU C6834
THR C6993
ALA C6843
THR C6846
1.64A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C7013
GLY C7011
LEU C7010
GLU C7015
1.65A19.55
None
NA  C7103 ( 4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
LEU C6892
THR C6880
ALA C6905
THR C6908
1.71A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
LEU A6892
THR A6880
ALA A6905
THR A6908
1.78A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
LYS A7075
LEU A7072
THR A6856
LEU A7078
1.71A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		4 / 7
LEU A6834
THR A6993
ALA A6843
THR A6846
1.63A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4360
GLY B4362
LEU B4365
ASN B4367
1.46A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU B 120
THR B 259
LEU B 117
SER B 103
1.54A20.75
None
None
None
CL  B 502 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU C 117
ALA C 116
LEU C 113
THR C 168
1.46A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU C 117
THR C 168
ALA C 116
LEU C 118
1.17A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LYS A 292
LEU A 290
THR A 281
THR A 277
1.24A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 117
THR A 168
ALA A 116
LEU A 118
1.17A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LYS C 274
THR C 115
LEU C 282
SER C 278
1.62A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 120
THR A 259
LEU A 117
SER A 103
1.57A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU B 117
THR B 168
ALA B 116
LEU B 118
1.08A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 117
THR A 168
ALA A 116
LEU A 118
1.10A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU C 117
THR C 168
ALA C 116
LEU C 118
1.24A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU B 117
THR B 168
ALA B 116
LEU B 118
1.13A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
THR B 119
ALA B 116
LEU B 113
THR B 115
1.55A20.75
None
None
None
CL  B 502 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU C 120
THR C 259
LEU C 117
SER C 103
1.56A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
LEU A  88
THR A  77
SER A 105
THR A 109
1.44A25.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
LEU A 103
ALA A 107
SER A 105
THR A 109
1.56A25.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 6
PRO A  -1
GLY A  -2
LEU A   4
ASN A   2
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 6
LEU A  59
THR B  89
LEU A  13
SER A  10
1.63A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
LYS B 261
THR B 263
ALA A 313
SER A 318
1.30A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS F 261
THR F 263
ALA E 313
SER E 318
1.29A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
LYS E 261
THR E 263
ALA F 313
SER F 318
1.32A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS E 261
THR E 263
ALA F 313
SER F 318
1.26A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS D 261
THR D 263
ALA C 313
SER C 318
1.24A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
LYS D 261
THR D 263
ALA C 313
SER C 318
1.31A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS A 261
THR A 263
ALA B 313
SER B 318
1.29A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS B 261
THR B 263
ALA A 313
SER A 318
1.24A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LYS C 261
THR C 263
ALA D 313
SER D 318
1.31A22.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU C6883
THR C6908
ALA C6905
LEU C6887
1.40A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6883
THR A6908
ALA A6905
LEU A6887
1.38A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C7013
GLY C7011
LEU C7010
GLU C7015
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6888
GLY A6890
ASN C7096
ASN A6862
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wjt NSP10
(SARS-CoV-2)		4 / 6
PRO B4360
GLY B4362
LEU B4365
ASN B4367
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C6888
GLY C6890
ASN A7096
ASN C6862
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LEU A  56
ALA A 173
SER B  78
THR B  76
1.40A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
THR B  54
LEU B 104
SER B 105
THR B  57
1.58A21.60
None
None
None
ZN  C 201 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LEU A 161
ALA A 173
LEU A 159
THR B  76
1.59A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 7
LEU C  56
ALA C 173
SER D  78
THR D  76
1.36A21.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO C7013
GLY C7011
LEU C7010
GLU C7015
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6888
GLY A6890
ASN C7096
ASN A6862
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU C6883
THR C6908
ALA C6905
LEU C6887
1.36A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
LEU A6883
THR A6908
ALA A6905
LEU A6887
1.37A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wkq NSP10
(SARS-CoV-2)		4 / 6
PRO B4360
GLY B4362
LEU B4365
ASN B4367
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wkq NSP16
(SARS-CoV-2)		4 / 6
GLY A6890
ASN C7096
LEU A6892
ASN A6862
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
PRO A  24
LEU A   3
ASN A   5
GLU A  22
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.38A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.68A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.60A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.42A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.65A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A7013
GLY A7011
LEU A7010
GLU A7015
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
LEU A6883
THR A6908
ALA A6905
LEU A6887
1.41A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
PRO B4360
GLY B4362
LEU B4365
ASN B4367
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU C  41
THR B  89
ALA B  86
THR B  84
1.42A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		4 / 6
THR C  46
ALA C  48
LEU C  40
SER C  10
1.49A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		4 / 7
THR C  46
ALA C  48
LEU C  40
SER C  10
1.51A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
LEU A  59
THR B  89
LEU A  13
SER A  10
1.62A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		4 / 6
LEU C  40
THR C  45
ALA C  42
LEU C  41
1.53A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU C  59
THR D  89
LEU C  13
SER C  10
1.58A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		4 / 7
LYS A  51
ALA A  48
SER A   4
THR A  45
1.57A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 7
LEU A  41
THR D  89
ALA D  86
THR D  84
1.45A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 6
LEU C  59
THR D  89
LEU C  13
SER C  10
1.59A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		4 / 7
LEU C  40
THR C  45
ALA C  42
LEU C  41
1.55A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.62A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.47A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.43A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 7
LEU A 117
THR A 168
ALA A 116
LEU A 118
1.12A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
LEU A 117
THR A 168
ALA A 116
LEU A 118
1.17A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
LEU A 120
THR A 259
LEU A 117
SER A 103
1.54A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 6
LYS A 217
LEU A 234
THR A 313
LEU A 185
1.63A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A  87
THR A  25
LEU A  89
THR A  21
1.71A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.64A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.72A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.64A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.60A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.43A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.40A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.67A21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
LEU A  41
THR D  89
ALA D  86
THR D  84
1.46A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 7
LEU C  41
THR B  89
ALA B  86
THR B  84
1.46A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU C  59
THR D  89
LEU C  13
SER C  10
1.64A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU A  59
THR B  89
LEU A  13
SER A  10
1.63A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU C  11
THR C  80
ALA C  19
SER C  14
1.40A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
LEU B 128
THR B 187
ALA B 141
SER B 131
1.48A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU H 128
THR H 187
ALA H 141
SER H 131
1.24A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR L 178
LEU L 141
SER L 182
THR L 170
1.31A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR H 104
LEU E 513
SER E 514
THR E 430
1.54A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B 127
GLY B 143
LEU B 142
GLU B 216
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
LEU C  11
THR C  80
ALA C  19
SER C  14
1.48A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU H 142
THR H 139
ALA H 140
SER H 131
1.38A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU E 517
ALA E 522
LEU E 518
THR E 523
1.59A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H 123
GLY H 122
LEU H 179
GLU H 152
1.75A
None
None
MLI  H 301 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
LEU H 128
THR H 187
ALA H 141
SER H 131
1.19A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L  11
THR L  80
ALA L  19
SER L  14
1.43A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
LEU L  11
THR L  80
ALA L  19
SER L  14
1.52A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR B 104
LEU A 513
SER A 514
THR A 430
1.57A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
THR B 114
ALA B  92
SER B  89
THR B  91
1.46A21.10
MLI  B 304 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 7
THR H 114
ALA H  92
SER H  89
THR H  91
1.49A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H 127
GLY H 143
LEU H 142
GLU H 216
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
LEU H 128
THR H 187
ALA H 141
SER H 131
1.24A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 7
THR H 114
ALA H  92
SER H  89
THR H  91
1.52A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR H 104
LEU E 513
SER E 514
THR E 430
1.56A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H 127
GLY H 143
LEU H 142
GLU H 216
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
LEU H 128
THR H 187
ALA H 141
SER H 131
1.19A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L  39
THR L  59
ALA L  57
SER L  73
1.52A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L 181
ALA L 150
LEU L 142
THR L 203
1.35A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU E 517
ALA E 522
LEU E 518
THR E 523
1.58A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR L 178
LEU L 141
SER L 182
THR L 170
1.39A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
THR L 115
ALA L 117
SER L 180
THR L 178
1.33A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L  11
THR L  80
ALA L  19
SER L  14
1.42A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.61A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.49A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.62A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LYS A 137
ALA A 129
SER A 113
THR A 111
1.49A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.65A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
LEU H 128
THR H 187
ALA H 141
SER H 131
1.18A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU B 128
THR B 187
ALA B 141
SER B 131
1.24A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
LEU L  11
THR L  80
ALA L  19
SER L  14
1.43A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
LEU C  11
THR C  80
ALA C  19
SER C  14
1.44A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU H 128
THR H 187
ALA H 141
SER H 131
1.24A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU H 142
THR H 139
ALA H 140
SER H 131
1.38A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
LEU B 128
THR B 187
ALA B 141
SER B 131
1.19A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR H 104
LEU E 513
SER E 514
THR E 430
1.55A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
THR L 178
LEU L 141
SER L 182
THR L 170
1.32A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H 123
GLY H 122
LEU H 179
GLU H 152
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
THR B 114
ALA B  92
SER B  89
THR B  91
1.49A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
LEU L  11
THR L  80
ALA L  19
SER L  14
1.52A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B 127
GLY B 143
LEU B 142
GLU B 216
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 6
LEU C  11
THR C  80
ALA C  19
SER C  14
1.52A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
THR C 178
LEU C 141
SER C 182
THR C 170
1.32A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H 127
GLY H 143
LEU H 142
GLU H 216
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU A 517
ALA A 522
LEU A 518
THR A 523
1.59A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
LEU E 517
ALA E 522
LEU E 518
THR E 523
1.59A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 7
THR B 104
LEU A 513
SER A 514
THR A 430
1.55A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
LEU B 142
THR B 139
ALA B 140
SER B 131
1.39A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 7
THR H 114
ALA H  92
SER H  89
THR H  91
1.49A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B 123
GLY B 122
LEU B 179
GLU B 152
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LYS A 137
ALA A 129
SER A 113
THR A 111
1.58A18.77
None
None
None
CL  A 406 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.67A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.47A18.77
None
IMD  A 402 (-3.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.63A18.77
None
IMD  A 402 (-3.1A)
None
PEG  A 404 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.66A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.43A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.66A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.59A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.39A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.62A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.57A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU A 387
ALA B 152
LEU B 128
THR B 148
1.58A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 252
ALA A 250
THR A 248
1.57A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 131
ALA A 130
LEU A 127
THR A 141
1.52A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 372
THR A 538
ALA A 376
LEU A 371
1.60A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 389
THR A 324
LEU A 388
SER A 672
1.65A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 576
ALA A 580
SER A 578
THR A 582
1.56A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 931
THR A 926
ALA A 923
SER A 913
1.66A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 246
ALA A 250
THR A 252
1.54A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 248
ALA A 250
THR A 246
1.55A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 372
THR A 538
ALA A 376
LEU A 371
1.60A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7btf NSP7
(SARS-CoV-2)		4 / 6
LYS C  51
THR C  46
ALA C  48
LEU C  40
1.68A20.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
LEU B 103
ALA B 125
LEU B  98
SER A 384
1.67A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A  19
THR A  28
LEU A   8
THR A  24
1.59A10.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 224
ALA A 266
LEU A 272
1.62A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LYS A 236
LEU A 232
ALA A 234
THR A 201
1.60A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 268
THR A 225
ALA A 266
LEU A 271
1.61A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.43A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 224
ALA A 266
LEU A 268
1.39A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
LEU A 205
THR A 225
ALA A 266
LEU A 208
1.68A19.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
LEU A 131
ALA A 130
LEU A 127
THR A 141
1.55A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 638
THR A 586
LEU A 575
SER A 578
1.57A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 372
THR A 538
ALA A 376
LEU A 371
1.52A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
LEU C  59
THR D  93
LEU C  13
SER C  10
1.67A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 207
THR A 248
LEU A 240
SER A 239
1.58A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
LEU A 207
THR A 248
LEU A 240
SER A 239
1.58A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		4 / 7
LEU C  40
THR C  45
ALA C  42
LEU C  41
1.56A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		4 / 7
THR C  46
ALA C  48
LEU C  40
SER C  10
1.57A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ASN A 790
LEU A 630
ASN A 628
GLU A 350
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU A 387
ALA B 152
LEU B 128
THR B 148
1.56A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		4 / 6
LEU C  40
THR C  45
ALA C  42
LEU C  41
1.54A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		4 / 6
LYS C  51
THR C  46
ALA C  48
LEU C  40
1.67A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
THR A 870
ALA A 866
LEU A 862
SER A 861
1.68A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 7
LYS A 391
LEU A 389
THR A 394
LEU A 388
SER A 672
1.78A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		4 / 6
THR C  46
ALA C  48
LEU C  40
SER C  10
1.54A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
LEU A 131
ALA A 130
LEU A 127
THR A 141
1.55A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 372
THR A 538
ALA A 376
LEU A 371
1.56A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 207
THR A 248
LEU A 240
SER A 239
1.61A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 6
LEU A 575
THR A 643
ALA A 639
LEU A 638
SER A 635
1.65A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
LEU A 186
THR A 252
LEU A 187
THR A 259
1.58A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
LEU A 387
ALA B 152
LEU B 128
THR B 148
1.53A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv2 NSP7
(SARS-CoV-2)		4 / 6
LEU C  40
THR C  45
ALA C  42
LEU C  41
1.58A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		7bv2 NSP7
(SARS-CoV-2)		4 / 6
THR C  46
ALA C  48
LEU C  40
SER C  10
1.51A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ASN A 790
LEU A 630
ASN A 628
GLU A 350
1.56A
None