Ligand ID: TZN


Drugbank ID:
DB01162
(Terazosin)


Indication:
For the treatment of symptomatic BPH and mild to moderate hypertension.

Get human targets for TZN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'TZN'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY B 104
LEU B 103
PHE B  75
LEU B 112
VAL B 110
0.98A15.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY B 104
LEU B 103
PHE B  75
LEU B 112
VAL B 110
1.00A16.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 138
GLY B   2
THR B 285
GLY A 170
VAL A 171
1.31A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		1uw7 NSP9
(SARS-COV
HKU-39849)		5 / 12
GLY A 100
PHE A  90
LEU A  42
LEU A 106
GLY A 104
1.16A16.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		1uw7 NSP9
(SARS-COV
HKU-39849)		5 / 12
GLY A 100
PHE A  90
LEU A  42
LEU A 106
GLY A 104
1.24A16.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		6 / 12
GLY C 229
GLY C 228
MET C 243
LEU C 235
GLY C 230
VAL C 231
1.58A17.68
GOL  C1009 (-4.0A)
GOL  C1009 (-3.4A)
None
None
GOL  C1005 ( 3.7A)
GOL  C1005 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
GLY B 230
ALA B 234
GLY B 229
GLY B 233
THR C 195
1.18A18.18
None
None
GOL  B1004 (-4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2ajf ACE2
(Homo
sapiens)		5 / 12
ALA A 264
THR A 276
PHE A 452
GLY A 486
VAL A 485
1.23A23.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY B 146
GLY B  29
THR B  35
PHE B  66
LEU B  87
VAL B  42
1.79A19.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY B 146
GLY B  29
THR B  35
PHE B  66
LEU B  87
VAL B  42
1.76A18.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 137
THR H 193
LEU H 138
LEU H 159
GLY H 162
VAL H 163
1.60A17.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 137
THR H 193
LEU H 138
LEU H 159
GLY H 162
VAL H 163
1.64A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		6 / 12
GLY B  48
GLY B  47
MET B  62
LEU B  54
GLY B  49
VAL B  50
1.62A15.27
APR  B 477 (-3.6A)
APR  B 477 (-3.7A)
None
None
APR  B 477 (-3.5A)
APR  B 477 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA C  51
GLY C  47
GLY C  48
PHE C 133
GLY B 104
1.27A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY C  29
GLY C  33
PHE C  32
THR C  11
VAL C  42
1.24A23.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		6 / 12
GLY X 121
ALA X  54
GLY X  52
THR X 101
PHE X 110
GLY X 127
1.78A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
GLY A 116
GLY A   1
GLY A   1
LEU A 112
VAL A   3
1.30A15.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
GLY A  71
GLY A  71
GLY A  71
LEU A  66
VAL A  74
1.17A15.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
GLY A 116
GLY A 116
THR A  68
LEU A  66
GLY A 116
1.21A15.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2ghw SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 12
GLY A 368
ALA A 371
LEU A 374
PHE A 364
LEU A 499
GLY A 418
1.77A17.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 12
GLY A 246
GLY A 238
GLY A 247
MET A 251
LEU A 254
1.34A23.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.28A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.29A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
GLY B 174
ALA B 173
THR D   1
LEU B 167
VAL B 186
1.29A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2qc2 3C-LIKE PROTEINASE
(-)		6 / 12
GLY B 146
GLY B  29
THR B  35
PHE B  66
LEU B  87
VAL B  42
1.77A18.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.33A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
GLY B 246
GLY B 238
GLY B 247
MET B 251
LEU B 254
1.21A23.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
GLY B 246
GLY B 238
GLY B 247
MET B 251
LEU B 254
1.22A23.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		2wct NSP3
(SARSr-CoV)		5 / 12
ALA D 620
GLY D 609
PHE B 406
GLY D 614
VAL D 611
1.34A21.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3atw 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY B 146
GLY B  29
THR B  35
PHE B  66
LEU B  87
VAL B  42
1.77A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3bgf F26G19 FAB
(Mus
musculus)		5 / 12
GLY H  42
GLY H  44
LEU H  45
PHE H  91
VAL H  89
1.26A18.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A 264
THR A 276
PHE A 452
GLY A 486
VAL A 485
1.21A23.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B 264
THR B 276
LEU B 267
GLY B 486
VAL B 485
1.25A23.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY A 146
GLY A  29
THR A  35
PHE A  66
LEU A  87
VAL A  42
1.79A19.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3e9s NSP3
(SARSr-CoV)		5 / 12
GLY A  29
GLY A  33
PHE A  32
THR A  11
VAL A  42
1.22A23.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY A 143
PHE A 150
MET A  17
LEU A 115
GLY A 124
VAL A 125
1.79A19.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLY A 146
GLY A  29
THR A  35
LEU A  87
VAL A  42
1.30A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY A 146
GLY A  29
THR A  35
PHE A  66
LEU A  87
VAL A  42
1.69A19.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
GLY A  29
GLY A  33
PHE A  32
THR A  11
VAL A  42
1.28A23.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
GLY A  29
GLY A  33
PHE A  32
THR A  11
VAL A  42
1.16A23.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3scj ACE2
(Homo
sapiens)		5 / 12
ALA B 264
THR B 276
PHE B 452
GLY B 486
VAL B 485
1.20A23.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
THR B 593
LEU B 595
PHE B 588
LEU B 236
VAL B 447
1.30A23.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A 264
THR A 276
PHE A 452
GLY A 486
VAL A 485
1.22A23.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		3vb4 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
GLY B 146
GLY B  29
THR B  35
PHE B  66
LEU B  87
VAL B  42
1.73A19.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
GLY A  29
GLY A  33
PHE A  32
THR A  11
VAL A  42
1.24A22.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY D  29
GLY D  33
PHE D  32
THR D  11
VAL D  42
1.23A22.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.42A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A  29
GLY A 120
THR A  24
LEU A  27
VAL A  68
1.60A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.69A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 210
THR A 280
LEU A 282
LEU A 287
VAL A 204
1.64A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A  70
LEU A  75
LEU A  89
GLY A  29
VAL A  20
1.61A17.07
DMS  A 403 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.67A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.47A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A  70
LEU A  75
LEU A  89
GLY A  29
VAL A  20
1.65A17.07
DMS  A 403 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A  29
GLY A 120
THR A  24
LEU A  27
VAL A  68
1.60A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLY D  29
GLY D  33
PHE D  32
THR D  11
VAL D  42
1.22A23.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA A 926
PHE A 805
LEU A 804
GLY A1041
VAL A1042
1.18A15.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA A 926
PHE A 805
LEU A 804
GLY A1041
VAL A1042
1.25A15.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 350
GLY B 512
PHE B 316
PHE B 379
LEU B 377
1.20A16.33
ALA  B 350 ( 0.0A)
GLY  B 512 ( 0.0A)
PHE  B 316 ( 1.3A)
PHE  B 379 ( 1.3A)
LEU  B 377 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA B 350
GLY B 512
PHE B 316
PHE B 379
LEU B 377
1.22A16.32
ALA  B 350 ( 0.0A)
GLY  B 512 ( 0.0A)
PHE  B 316 ( 1.3A)
PHE  B 379 ( 1.3A)
LEU  B 377 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
GLY A  29
GLY A  33
PHE A  32
THR A  11
VAL A  42
1.26A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 350
GLY A 512
PHE A 316
PHE A 379
LEU A 377
1.28A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 350
GLY A 512
PHE A 316
PHE A 379
LEU A 377
1.28A16.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY A 871
GLY A 867
THR C 693
LEU A 876
GLY A 862
1.28A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY B 873
ALA B 875
GLY B 871
LEU B 859
VAL B 767
1.29A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6cs2 ACE2
(Homo
sapiens)		5 / 12
ALA D 264
THR D 276
PHE D 452
GLY D 486
VAL D 485
1.23A23.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6cs2 ACE2
(Homo
sapiens)		6 / 12
ALA D 264
THR D 276
LEU D 267
PHE D 452
GLY D 486
VAL D 485
1.41A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6lzg ACE2
(Homo
sapiens)		5 / 12
ALA A 264
THR A 276
LEU A 267
GLY A 486
VAL A 485
1.23A23.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m0j ACE2
(Homo
sapiens)		5 / 12
ALA A 264
THR A 276
LEU A 267
GLY A 486
VAL A 485
1.23A23.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
GLY A 438
GLY A 285
GLY A 284
PHE A 277
GLY A 434
1.22A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
GLY C  68
ALA C  69
GLY C  67
GLY C  66
LEU C  61
1.24A20.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY D 146
GLY D  29
PHE D  66
LEU D  87
VAL D  42
1.44A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY C   2
THR C 280
GLY A 170
VAL A 171
1.35A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY C 146
GLY C  29
THR C  98
LEU C  30
GLY C 120
1.43A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY C 146
GLY C  29
THR C  98
LEU C  30
GLY C 120
1.38A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY C 138
GLY A   2
THR A 280
GLY C 170
VAL C 171
1.39A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 138
GLY C   2
THR C 280
GLY A 170
VAL A 171
1.36A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY B 138
GLY D   2
THR D 280
GLY B 170
VAL B 171
1.37A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY D 146
GLY D  29
THR D  98
LEU D  30
GLY D 120
1.38A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY B 138
GLY D   2
THR D 280
GLY B 170
VAL B 171
1.39A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY B 146
GLY B  29
THR B  98
LEU B  30
GLY B 120
1.40A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.44A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY D 146
GLY D  29
THR D  98
LEU D  30
GLY D 120
1.43A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY B 146
GLY B  29
THR B  98
LEU B  30
GLY B 120
1.44A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.40A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY D 138
GLY B   2
THR B 280
GLY D 170
VAL D 171
1.41A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY C 138
GLY A   2
THR A 280
GLY C 170
VAL C 171
1.42A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.40A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.45A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6m71 NSP12
(SARS-CoV-2)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.54A18.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 151
THR H 207
LEU H 152
LEU H 173
GLY H 176
VAL H 177
1.67A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 151
THR H 207
LEU H 152
LEU H 173
GLY H 176
VAL H 177
1.63A18.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6nur NSP12
(SARSr-CoV)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.56A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 363
GLY B 526
PHE B 329
PHE B 515
LEU B 390
1.29A16.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY A  97
GLY A  78
LEU A 109
PHE A 116
GLY A  79
VAL A  95
1.71A
None
None
None
None
SO4  A 201 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxs NSP3
(SARS-CoV-2)		6 / 12
GLY B  97
GLY B  78
LEU B 109
PHE B 116
GLY B  79
VAL B  95
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 363
GLY A 526
PHE A 329
PHE A 392
LEU A 390
1.30A16.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 363
GLY A 526
PHE A 329
PHE A 392
LEU A 390
1.30A16.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 363
GLY A 526
PHE A 329
PHE A 515
LEU A 390
1.25A16.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w02 NSP3
(SARS-CoV-2)		5 / 12
ALA A  39
GLY A  46
LEU A  53
GLY A  48
VAL A  49
1.28A18.86
None
APR  A 201 (-3.7A)
None
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w02 NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.17A18.77
None
APR  A 201 ( 3.7A)
EDO  A 202 (-3.8A)
APR  A 201 (-3.4A)
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ALA H  93
GLY H  95
GLY H  94
THR H  77
LEU H   4
1.64A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ALA H  93
GLY H  95
GLY H  94
THR H  77
GLY H  97
1.55A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		6 / 12
ALA H 137
THR H 193
LEU H 138
LEU H 159
GLY H 162
VAL H 163
1.71A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		6 / 12
ALA H 137
THR H 193
LEU H 138
LEU H 159
GLY H 162
VAL H 163
1.64A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
GLY H  35
GLY H  95
GLY H  94
LEU H   4
PHE H  29
1.61A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ALA L  34
THR L  69
LEU L  33
LEU L   4
GLY L  99
1.61A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
GLY H  95
GLY H  94
LEU L  46
PHE L  98
GLY H  35
1.46A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
GLY L 200
ALA L 112
THR L 164
LEU L 136
VAL L 196
1.77A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
GLY H  35
GLY H  95
GLY H  94
LEU H   4
PHE H  29
1.51A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ALA H  93
GLY H  95
GLY H  94
THR H  77
LEU H   4
1.56A15.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
GLY L 200
ALA L 112
THR L 164
LEU L 136
VAL L 196
1.76A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w4b NSP9
(SARS-CoV-2)		5 / 12
GLY B 105
LEU B 104
PHE B  76
LEU B 113
VAL B 111
1.09A16.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w4b NSP9
(SARS-CoV-2)		5 / 12
GLY B 105
LEU B 104
PHE B  76
LEU B 113
VAL B 111
1.10A16.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6959
LEU A6924
1.71A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
GLY B4322
GLY B4347
GLY B4323
LEU B4345
VAL A6902
1.78A16.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4305
THR B4354
PHE B4363
GLY B4380
1.66A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
GLY A7006
THR A6854
LEU A6857
GLY A6963
1.58A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6843
PHE A7003
PHE A7048
GLY A6879
VAL A6882
1.53A16.55
None
None
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6959
LEU A6924
1.73A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
GLY A6871
ALA A6877
GLY A6869
THR A6846
LEU A6883
1.79A16.55
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.44A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 NSP10
(SARS-CoV-2)		5 / 12
GLY B4374
ALA B4307
THR B4354
PHE B4363
GLY B4380
1.76A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6986
GLY A6962
LEU A7010
LEU A7072
GLY A7076
1.67A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6963
THR A6856
LEU A7010
GLY A7011
1.80A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6870
GLY A6869
PHE A6868
LEU A6909
GLY A6911
1.64A16.55
None
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
GLY A7006
THR A6854
LEU A6857
GLY A6963
1.68A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4380
THR B4354
PHE B4363
GLY B4378
1.67A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6857
GLY A7076
1.63A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6881
GLY B4323
GLY B4322
THR B4292
VAL A6902
1.52A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6870
GLY A6869
PHE A6868
LEU A6909
GLY A6911
1.62A16.55
None
SAM  A7104 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4380
THR B4354
PHE B4363
GLY B4378
1.66A16.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6881
GLY B4323
GLY B4322
THR B4292
VAL A6902
1.58A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 134
GLY B 130
GLY B 133
PHE B 132
LEU B 127
1.72A16.82
None
MES  B 201 ( 3.4A)
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
ALA B 134
LEU B 109
LEU B 126
GLY B 130
1.62A17.38
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.68A16.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  79
LEU B  93
PHE B 116
LEU B 127
GLY B  78
1.79A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.50A17.38
None
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  52
GLY B  47
GLY B  48
GLY B  46
1.74A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 130
PHE B 132
LEU B 127
GLY B  48
VAL B  49
1.53A17.38
MES  B 201 ( 3.4A)
MES  B 201 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  97
GLY B  78
PHE B 116
GLY B  79
VAL B  95
1.51A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  46
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.52A16.82
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  46
GLY B  47
PHE B 132
1.72A16.82
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  97
GLY A  78
PHE A 116
GLY A  79
VAL A  95
1.51A16.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 133
ALA B 134
LEU B 109
LEU B 126
GLY B 130
1.47A16.82
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  97
THR A 146
LEU A 109
PHE A 116
VAL A  95
1.75A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
GLY B  47
GLY B  48
PHE B 132
GLY B  46
1.53A16.82
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 129
GLY B 130
PHE B 132
GLY B  48
VAL B  49
1.34A
None
MES  B 201 ( 3.4A)
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.34A
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.43A
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.62A
None
None
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A 134
GLY A 130
GLY A 133
PHE A 132
LEU A 127
1.64A16.82
None
AMP  A 201 ( 3.5A)
None
AMP  A 201 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  78
ALA A 112
GLY A  97
PHE A 132
LEU A 127
1.52A17.38
None
None
None
AMP  A 201 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  79
LEU A  93
PHE A 116
LEU A 127
GLY A  78
1.79A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  78
ALA B 112
GLY B  97
PHE B 132
LEU B 127
1.57A17.38
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 130
PHE A 132
LEU A 127
GLY A  48
VAL A  49
1.72A17.38
AMP  A 201 ( 3.5A)
AMP  A 201 ( 4.3A)
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  78
ALA B 112
GLY B  97
PHE B 132
LEU B 127
1.66A16.82
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A 134
GLY A 130
GLY A 133
PHE A 132
LEU A 127
1.75A17.38
None
AMP  A 201 ( 3.5A)
None
AMP  A 201 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
GLY B  47
GLY B  48
PHE B 132
GLY B  46
1.49A17.38
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  46
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.50A17.38
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
ALA A 134
LEU A 109
LEU A 126
GLY A 130
1.45A
None
None
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 130
PHE A 132
LEU A 127
GLY A  48
VAL A  49
1.72A16.82
AMP  A 201 ( 3.5A)
AMP  A 201 ( 4.3A)
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.62A
None
None
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  52
GLY B  47
GLY B  48
GLY B  46
1.79A16.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  97
GLY B  78
PHE B 116
GLY B  79
VAL B  95
1.51A16.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  46
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.53A17.38
None
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 129
GLY B 130
PHE B 132
GLY B  48
VAL B  49
1.30A
None
MES  B 201 ( 3.4A)
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  78
ALA A 112
GLY A  97
PHE A 132
LEU A 127
1.63A16.82
None
None
None
AMP  A 201 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  52
GLY A  47
GLY A  48
GLY A  46
1.72A16.82
None
AMP  A 201 ( 4.0A)
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  97
GLY A  78
PHE A 116
GLY A  79
VAL A  95
1.52A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B 130
PHE B 132
LEU B 127
GLY B  48
VAL B  49
1.52A16.82
MES  B 201 ( 3.4A)
MES  B 201 ( 3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  46
GLY B  47
PHE B 132
1.66A17.38
None
MES  B 201 ( 3.7A)
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY B  97
THR B 146
LEU B 109
PHE B 116
VAL B  95
1.77A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A 133
ALA A 134
LEU A 109
LEU A 126
GLY A 130
1.58A17.38
None
None
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  46
ALA A  50
GLY A  47
GLY A  51
LEU A  53
1.70A16.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  46
GLY A  47
PHE A 132
1.80A17.38
None
None
None
None
AMP  A 201 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A  46
ALA A  50
GLY A  47
GLY A  51
LEU A  53
1.74A17.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4380
THR B4354
PHE B4363
GLY B4378
1.74A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
GLY B4347
ALA B4324
GLY B4322
THR B4292
VAL B4350
1.79A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA D4307
GLY D4305
THR D4354
PHE D4363
GLY D4380
1.72A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
GLY B4322
GLY B4347
GLY B4323
LEU B4345
VAL A6902
1.75A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
GLY A7006
THR A6854
LEU A6857
GLY A6963
1.73A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6857
GLY A7076
1.56A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
GLY D4347
ALA D4324
GLY D4322
THR D4292
VAL D4350
1.78A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6986
GLY C6962
LEU C7010
LEU C7072
GLY C7076
1.63A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
THR A6889
LEU A6887
PHE A7048
GLY A6879
VAL A6882
1.62A16.67
None
None
None
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6881
GLY D4323
GLY D4322
THR D4292
VAL C6902
1.53A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6870
GLY C6869
PHE C6868
LEU C6909
GLY C6911
1.64A16.67
None
SAM  C7105 ( 3.8A)
None
None
NA  C7104 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
GLY A7006
THR A6854
LEU A6857
GLY A6963
1.63A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6843
THR D4300
LEU D4298
PHE C7043
GLY C6837
1.34A16.67
None
None
None
None
FMT  D4404 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
GLY C7006
THR C6854
LEU C6857
GLY C6963
1.71A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.42A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6986
GLY A6962
LEU A7010
LEU A7072
GLY A7076
1.63A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
GLY B4322
GLY B4347
GLY B4323
LEU B4345
VAL A6902
1.71A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6870
GLY A6869
PHE A6868
LEU A6909
GLY A6911
1.66A18.28
None
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA D4307
GLY D4380
THR D4354
PHE D4363
GLY D4378
1.72A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
GLY D4322
GLY D4347
GLY D4323
LEU D4345
VAL C6902
1.68A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6870
GLY C6869
PHE C6868
LEU C6909
GLY C6911
1.66A18.28
None
SAM  C7105 ( 3.8A)
None
None
NA  C7104 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6960
GLY C6962
GLY C6963
LEU C6959
LEU C6924
1.72A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6881
GLY B4323
GLY B4322
THR B4292
VAL A6902
1.61A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6881
GLY D4323
GLY D4322
THR D4292
VAL C6902
1.58A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6960
GLY C6962
GLY C6963
LEU C6959
LEU C6924
1.69A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6959
LEU A6924
1.69A18.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4305
THR B4354
PHE B4363
GLY B4380
1.76A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6870
GLY A6869
PHE A6868
LEU A6909
GLY A6911
1.64A16.67
None
SAM  A7102 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
GLY C7006
THR C6854
LEU C6857
GLY C6963
1.60A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6881
GLY B4323
GLY B4322
THR B4292
VAL A6902
1.56A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.32A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6960
GLY A6962
GLY A6963
LEU A6959
LEU A6924
1.71A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
GLY D4322
GLY D4347
GLY D4323
LEU D4345
VAL C6902
1.72A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA B4307
GLY B4380
THR B4354
PHE B4363
GLY B4378
1.75A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6843
PHE C7003
PHE C7048
GLY C6879
VAL C6882
1.52A16.67
None
None
None
SAM  C7105 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ALA D4307
GLY D4380
THR D4354
PHE D4363
GLY D4378
1.72A16.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6843
THR D4300
LEU D4298
PHE C7043
GLY C6837
1.46A18.28
None
None
None
None
FMT  D4404 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6843
PHE A7003
PHE A7048
GLY A6879
VAL A6882
1.52A16.67
None
None
None
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY C  28
GLY C  32
PHE C  31
THR C  10
VAL C  41
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A  28
GLY A  32
PHE A  31
THR A  10
VAL A  41
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A  28
GLY A  32
PHE A  31
THR A  10
VAL A  41
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY B  28
GLY B  32
PHE B  31
THR B  10
VAL B  41
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY B  28
GLY B  32
PHE B  31
THR B  10
VAL B  41
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLY C  28
GLY C  32
PHE C  31
THR C  10
VAL C  41
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
GLY A 100
PHE A  90
LEU A  42
LEU A 106
GLY A 104
0.87A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
GLY A 100
PHE A  90
LEU A  42
LEU A 106
GLY A 104
0.83A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.70A
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.31A
None
MES  A 201 (-3.2A)
MES  A 201 (-2.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.28A
None
MES  A 201 (-3.2A)
MES  A 201 (-2.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.39A
MES  A 202 (-3.3A)
MES  A 201 ( 3.0A)
MES  A 202 (-3.4A)
None
MES  A 201 (-2.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.71A
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.30A
MES  A 202 (-3.3A)
MES  A 201 ( 3.0A)
MES  A 202 (-3.4A)
None
MES  A 201 (-2.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wcf NSP3
(SARS-CoV-2)		6 / 12
GLY A  97
GLY A  78
LEU A 109
PHE A 116
GLY A  79
VAL A  95
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wey NSP3
(SARS-CoV-2)		6 / 12
GLY A 301
GLY A 282
LEU A 313
PHE A 320
GLY A 283
VAL A 299
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wey NSP3
(SARS-CoV-2)		5 / 12
GLY A 250
ALA A 254
GLY A 251
GLY A 252
PHE A 336
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wey NSP3
(SARS-CoV-2)		6 / 12
GLY A 251
GLY A 250
MET A 265
LEU A 257
GLY A 252
VAL A 253
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wey NSP3
(SARS-CoV-2)		6 / 12
GLY A 251
GLY A 250
MET A 265
LEU A 257
GLY A 252
VAL A 253
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wey NSP3
(SARS-CoV-2)		5 / 12
GLY A 255
ALA A 254
GLY A 251
GLY A 252
PHE A 336
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA C6843
THR D4300
LEU D4298
PHE C7043
GLY C6837
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.34A
None
None
FMT  B4403 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA C 173
LEU C 159
PHE C  66
LEU C  64
GLY C 170
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA C6843
THR D4300
LEU D4298
PHE C7043
GLY C6837
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D  51
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.20A
None
APR  D 201 ( 3.7A)
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B 129
GLY B 130
PHE B 132
GLY B  48
VAL B  49
1.44A
APR  B 201 (-3.7A)
APR  B 201 (-3.3A)
APR  B 201 (-3.6A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY A  97
GLY A  78
LEU A 109
PHE A 116
GLY A  79
VAL A  95
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B  39
GLY B  46
LEU B  53
GLY B  48
VAL B  49
1.35A
None
APR  B 201 (-3.7A)
None
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.64A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
None
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B  39
GLY B  46
LEU B  53
GLY B  48
VAL B  49
1.28A
None
APR  B 201 (-3.7A)
None
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C 129
GLY C 130
PHE C 132
GLY C  48
VAL C  49
1.42A
APR  C 201 (-3.7A)
APR  C 201 (-3.0A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D  46
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.42A
APR  D 201 (-3.8A)
APR  D 201 ( 3.7A)
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.27A
None
APR  B 201 (-3.3A)
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C  39
GLY C  46
LEU C  53
GLY C  48
VAL C  49
1.27A
None
APR  C 201 (-3.9A)
None
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D 129
GLY D 130
PHE D 132
GLY D  48
VAL D  49
1.41A
APR  D 201 (-3.7A)
APR  D 201 (-3.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C  51
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.21A
None
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  39
GLY A  46
LEU A  53
GLY A  48
VAL A  49
1.37A
None
APR  A 201 (-3.9A)
None
APR  A 201 (-3.5A)
APR  A 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.64A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
None
APR  A 201 (-3.5A)
APR  A 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B 129
GLY B 130
PHE B 132
GLY B  48
VAL B  49
1.42A
APR  B 201 (-3.7A)
APR  B 201 (-3.3A)
APR  B 201 (-3.6A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY B  46
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.37A
APR  B 201 (-3.7A)
APR  B 201 (-3.3A)
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D  39
GLY D  46
LEU D  53
GLY D  48
VAL D  49
1.36A
None
APR  D 201 (-3.8A)
None
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  39
GLY A  46
LEU A  53
GLY A  48
VAL A  49
1.30A
None
APR  A 201 (-3.9A)
None
APR  A 201 (-3.5A)
APR  A 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D  39
GLY D  46
LEU D  53
GLY D  48
VAL D  49
1.29A
None
APR  D 201 (-3.8A)
None
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY D  51
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.33A
None
APR  D 201 ( 3.7A)
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.15A
None
APR  B 201 (-3.3A)
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.61A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
None
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.67A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
None
APR  A 201 (-3.5A)
APR  A 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  46
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.36A
APR  A 201 (-3.9A)
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.29A
None
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C  39
GLY C  46
LEU C  53
GLY C  48
VAL C  49
1.35A
None
APR  C 201 (-3.9A)
None
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.63A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
None
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.66A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
None
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.18A
None
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C  46
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.43A
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.63A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
None
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY C  51
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.33A
None
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.62A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
None
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  46
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.37A
APR  A 201 (-3.9A)
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C 129
GLY C 130
PHE C 132
GLY C  48
VAL C  49
1.39A
APR  C 201 (-3.7A)
APR  C 201 (-3.0A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
APR  C 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D 129
GLY D 130
PHE D 132
GLY D  48
VAL D  49
1.42A
APR  D 201 (-3.7A)
APR  D 201 (-3.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.5A)
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA A6843
THR B4300
LEU B4298
PHE A7043
GLY A6837
1.34A
None
SO4  B4403 (-3.2A)
None
None
SO4  A7108 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
GLY A  28
GLY A  32
PHE A  31
THR A  10
VAL A  41
1.26A
None
None
None
CL  A 506 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
GLY A  28
GLY A  32
PHE A  31
THR A  10
VAL A  41
1.39A
None
None
None
CL  A 506 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 138
GLY B   2
THR B 280
GLY A 170
VAL A 171
1.31A20.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 138
GLY B   2
THR B 280
GLY A 170
VAL A 171
1.34A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  70
LEU A  75
LEU A  89
GLY A  29
VAL A  20
1.66A17.07
DMS  A 406 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.66A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.42A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
THR A 190
PHE A 185
LEU A 167
GLY A 170
VAL A 171
1.68A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  29
GLY A 120
THR A  24
LEU A  27
VAL A  68
1.61A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 210
THR A 280
LEU A 282
LEU A 287
VAL A 204
1.66A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.47A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  70
LEU A  75
LEU A  89
GLY A  29
VAL A  20
1.62A17.07
DMS  A 406 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A  29
GLY A 120
THR A  24
LEU A  27
VAL A  68
1.62A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
PHE A  66
LEU A  87
VAL A  42
1.64A17.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		6 / 12
GLY B  28
GLY B  26
PHE L  68
LEU L  53
GLY L  63
VAL L  64
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA B 141
THR B 197
LEU B 142
LEU B 163
GLY B 166
VAL B 167
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		6 / 12
GLY H  28
GLY H  26
PHE C  68
LEU C  53
GLY C  63
VAL C  64
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA B 141
THR B 197
LEU B 142
LEU B 163
GLY B 166
VAL B 167
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		6 / 12
GLY B  28
GLY B  26
PHE L  68
LEU L  53
GLY L  63
VAL L  64
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		6 / 12
GLY H  28
GLY H  26
PHE C  68
LEU C  53
GLY C  63
VAL C  64
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
GLY H  35
LEU H   4
PHE H  29
MET H   2
GLY H  99
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ym0 HEAVY CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
ALA B 141
THR B 197
LEU B 142
LEU B 163
GLY B 166
VAL B 167
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
ALA B 141
THR B 197
LEU B 142
LEU B 163
GLY B 166
VAL B 167
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yor IGG H CHAIN
(Homo
sapiens)		6 / 12
ALA H 141
THR H 197
LEU H 142
LEU H 163
GLY H 166
VAL H 167
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 146
GLY A  29
THR A  98
LEU A  30
GLY A 120
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  48
ALA B  52
GLY B  46
GLY B  51
GLY E 133
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
GLY E 133
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.66A
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
None
EDO  D 209 ( 4.7A)
EDO  D 209 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY E  47
GLY E  46
MET E  61
LEU E  53
GLY E  48
VAL E  49
1.68A
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
None
EPE  E 202 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY E  47
GLY E  46
MET E  61
LEU E  53
GLY E  48
VAL E  49
1.69A
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
None
EPE  E 202 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.64A
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
None
EDO  D 209 ( 4.7A)
EDO  D 209 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E  51
ALA E  50
GLY E  47
GLY E  48
PHE E 132
1.38A
None
EPE  E 202 (-3.1A)
EPE  E 202 (-4.3A)
EPE  E 202 ( 4.8A)
EPE  E 202 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.37A
None
None
None
None
EDO  A 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  48
ALA B  52
GLY B  46
GLY B  51
GLY E 133
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.66A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
None
APR  C 201 (-3.5A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D  51
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.31A
None
APR  D 201 (-3.6A)
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.60A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
None
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  39
GLY B  46
LEU B  53
GLY B  48
VAL B  49
1.38A
None
EDO  B 202 (-3.9A)
None
APR  B 201 (-3.5A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D  51
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.19A
None
APR  D 201 (-3.6A)
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C  51
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.34A
None
APR  C 201 (-3.6A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.66A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
None
EDO  D 204 ( 3.4A)
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  39
GLY A  46
LEU A  53
GLY A  48
VAL A  49
1.37A
None
APR  A 201 (-4.2A)
None
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA D  39
GLY D  46
LEU D  53
GLY D  48
VAL D  49
1.37A
None
APR  D 201 (-3.8A)
None
EDO  D 204 ( 3.4A)
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E  51
ALA E  50
GLY E  47
GLY E  48
PHE E 132
1.29A
None
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY D  47
GLY D  46
MET D  61
LEU D  53
GLY D  48
VAL D  49
1.64A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
None
EDO  D 204 ( 3.4A)
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  39
GLY C  46
LEU C  53
GLY C  48
VAL C  49
1.40A
None
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.37A
None
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
GLY E 133
1.27A
None
APR  B 201 (-3.5A)
APR  B 201 (-3.6A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C  51
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.21A
None
APR  C 201 (-3.6A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
GLY E 133
1.55A
None
APR  B 201 (-3.5A)
APR  B 201 (-3.6A)
APR  B 201 (-3.5A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.61A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
None
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA D  39
GLY D  46
LEU D  53
GLY D  48
VAL D  49
1.30A
None
APR  D 201 (-3.8A)
None
EDO  D 204 ( 3.4A)
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E 129
GLY E 130
PHE E 132
GLY E  48
VAL E  49
1.43A
APR  E 201 (-3.5A)
APR  E 201 (-3.2A)
APR  E 201 (-3.5A)
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.58A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
None
None
APR  B 201 (-3.5A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY E  47
GLY E  46
MET E  61
LEU E  53
GLY E  48
VAL E  49
1.64A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
None
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.60A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
None
None
APR  B 201 (-3.5A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C  46
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.33A
APR  C 201 (-4.3A)
APR  C 201 (-3.6A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E  46
ALA E  50
GLY E  47
GLY E  48
PHE E 132
1.35A
APR  E 201 (-3.9A)
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C  46
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.36A
APR  C 201 (-4.3A)
APR  C 201 (-3.6A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.39A
None
APR  B 201 (-3.5A)
APR  B 201 (-3.6A)
APR  B 201 (-3.5A)
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  39
GLY E  46
LEU E  53
GLY E  48
VAL E  49
1.28A
None
APR  E 201 (-3.9A)
None
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.41A
APR  A 201 ( 3.7A)
APR  A 201 ( 3.2A)
APR  A 201 (-3.7A)
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.43A
APR  A 201 ( 3.7A)
APR  A 201 ( 3.2A)
APR  A 201 (-3.7A)
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.64A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
None
APR  C 201 (-3.5A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D  46
ALA D  50
GLY D  47
GLY D  48
PHE D 132
1.37A
APR  D 201 (-3.8A)
APR  D 201 (-3.6A)
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E 129
GLY E 130
PHE E 132
GLY E  48
VAL E  49
1.42A
APR  E 201 (-3.5A)
APR  E 201 (-3.2A)
APR  E 201 (-3.5A)
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY E  51
ALA E  50
GLY E  47
GLY E  48
PHE E 132
1.17A
None
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  48
ALA B  52
GLY B  46
GLY B  51
GLY E 133
1.26A
APR  B 201 (-3.5A)
APR  B 201 ( 4.0A)
EDO  B 202 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY E  47
GLY E  46
MET E  61
LEU E  53
GLY E  48
VAL E  49
1.66A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
None
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  48
ALA B  52
GLY B  46
GLY B  51
GLY E 133
1.34A
APR  B 201 (-3.5A)
APR  B 201 ( 4.0A)
EDO  B 202 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  39
GLY C  46
LEU C  53
GLY C  48
VAL C  49
1.33A
None
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  39
GLY E  46
LEU E  53
GLY E  48
VAL E  49
1.35A
None
APR  E 201 (-3.9A)
None
APR  E 201 (-3.4A)
APR  E 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.26A
None
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-3.4A)
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY B  51
ALA B  50
GLY B  47
GLY B  48
PHE B 132
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.36A
None
MES  A 201 ( 3.7A)
MES  A 201 ( 4.8A)
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY A  51
ALA A  50
GLY A  47
GLY A  48
PHE A 132
1.44A
None
MES  A 201 ( 3.7A)
MES  A 201 ( 4.8A)
None
MES  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.66A
MES  C 201 ( 4.9A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.35A
None
MES  A 201 (-3.1A)
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C 129
GLY C 130
PHE C 132
GLY C  48
VAL C  49
1.42A
None
MES  C 201 (-3.3A)
MES  C 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY B  47
GLY B  46
MET B  61
LEU B  53
GLY B  48
VAL B  49
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.68A
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY C  51
ALA C  50
GLY C  47
GLY C  48
PHE C 132
1.41A
None
MES  C 201 ( 3.8A)
MES  C 201 ( 4.9A)
None
MES  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY C  47
GLY C  46
MET C  61
LEU C  53
GLY C  48
VAL C  49
1.64A
MES  C 201 ( 4.9A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
GLY A  47
GLY A  46
MET A  61
LEU A  53
GLY A  48
VAL A  49
1.66A
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A 129
GLY A 130
PHE A 132
GLY A  48
VAL A  49
1.30A
None
MES  A 201 (-3.1A)
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7btf NSP12
(SARS-CoV-2)		5 / 12
GLY A 839
ALA A 840
GLY A 841
LEU A 862
VAL A 844
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7btf NSP12
(SARS-CoV-2)		5 / 12
GLY A 839
ALA A 840
GLY A 841
LEU A 862
VAL A 844
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O3F_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.33A
None
U  P  18 ( 3.4A)
None
None
U  P  17 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
GLY A 839
ALA A 840
GLY A 841
PHE A 859
LEU A 862
VAL A 844
1.37A
None
U  P  18 ( 3.4A)
None
None
U  P  17 ( 4.9A)
None