Ligand ID: 9KL


Drugbank ID:
DB09214
(Dexketoprofen)


Indication:
For short-term treatment of mild to moderate pain, including dysmenorrhoea.

Get human targets for 9KL in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '9KL'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
SER D 321
ILE D 288
TYR D 295
LEU D 282
ALA D 311
1.28A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 12
TYR H 154
SER H 156
ILE H 112
LEU D  65
ALA H 155
1.61A17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
TYR D 334
PHE D 315
ILE C 338
GLY C 317
ALA C 314
1.49A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER A 319
TYR B 334
PHE B 315
ILE A 338
ALA A 314
1.68A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
PHE L  62
ILE L  58
TYR L  86
ARG L  61
GLY L  81
1.25A20.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2dd8 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE S 325
ILE S 345
LEU S 499
GLY S 512
LEU S 374
1.50A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
PHE A 117
LEU A 127
GLY A  79
ALA A 113
LEU A 110
1.62A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
SER C 140
ILE C 107
TYR C 114
LEU C 101
ALA C 130
1.26A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
TYR B 334
PHE B 315
ILE A 338
GLY A 317
ALA A 314
1.58A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2jzd REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
TYR A 644
ILE A 608
LEU A 627
ALA A 621
LEU A 648
1.64A17.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2jzd REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
TYR A 644
ILE A 608
LEU A 627
ALA A 621
LEU A 648
1.67A17.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE D 306
TYR D 237
LEU D 331
GLY D 253
LEU D 248
1.49A23.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		2wct NSP3
(SARSr-CoV)		5 / 12
TYR B 644
ILE B 608
LEU B 627
ALA B 621
LEU B 648
1.56A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2wct NSP3
(SARSr-CoV)		5 / 12
TYR D 644
ILE D 608
LEU D 627
ALA D 621
LEU D 648
1.60A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A 145
ILE A 171
LEU A 206
HIS A 225
ALA A 178
1.53A19.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A 145
ILE A 171
LEU A 206
HIS A 225
ALA A 178
1.55A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER B  77
PHE B  32
LEU B 391
ALA B  80
LEU B  97
1.55A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 446
TYR B 515
LEU B 410
GLY B 399
ALA B 403
1.57A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		3i6k HLA, A-2
MEMBRANE
GLYCOPROTEIN PEPTIDE
(Homo
sapiens;
SARS-COV
TJF)		5 / 12
TYR E  99
PHE G   4
LEU G   6
HIS E 114
LEU G   1
1.44A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		3i6k HLA, A-2
MEMBRANE
GLYCOPROTEIN PEPTIDE
(Homo
sapiens;
SARS-COV
TJF)		6 / 12
TYR E  99
PHE G   4
LEU G   6
HIS E 114
GLY E 100
LEU G   1
1.80A19.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
SER A 145
ILE A 171
LEU A 206
HIS A 225
ALA A 178
1.55A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		3scj ACE2
(Homo
sapiens)		5 / 12
ILE B 436
TYR B 587
LEU B 595
ALA B 443
LEU B 240
1.59A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		3scj ACE2
(Homo
sapiens)		5 / 12
ILE B 436
TYR B 587
LEU B 595
ALA B 443
LEU B 240
1.59A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
SER A  77
PHE A  32
LEU A 391
ALA A  80
LEU A  97
1.60A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 446
TYR B 515
LEU B 410
GLY B 399
ALA B 403
1.61A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ILE A 277
LEU A 283
HIS A 276
GLY A 288
LEU A 291
1.64A19.61
None
None
None
NHE  A 403 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
TYR B 511
PHE B 326
ILE B 397
ALA B 323
LEU B 322
1.63A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
TYR B 511
PHE B 326
ILE B 397
ALA B 323
LEU B 322
1.62A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
TYR B 511
PHE B 326
ILE B 397
ALA B 323
LEU B 322
1.60A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
TYR B 511
PHE B 326
ILE B 397
ALA B 323
LEU B 322
1.59A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
TYR D 511
PHE D 326
ILE D 397
ALA D 323
LEU D 322
1.59A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
TYR D 511
PHE D 326
ILE D 397
ALA D 323
LEU D 322
1.58A21.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
TYR C 598
LEU A 846
GLY C 634
ALA C 633
LEU A 843
1.37A15.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE B 325
ILE B 345
LEU B 499
GLY B 512
LEU B 374
1.27A16.16
PHE  B 325 ( 1.3A)
ILE  B 345 ( 0.7A)
LEU  B 499 ( 0.6A)
GLY  B 512 ( 0.0A)
LEU  B 374 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 500
TYR C 410
PHE C 387
ILE C 397
LEU C 421
1.37A16.16
SER  C 500 ( 0.0A)
TYR  C 410 ( 1.3A)
PHE  C 387 ( 1.3A)
ILE  C 397 ( 0.7A)
LEU  C 421 ( 0.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 500
TYR C 410
PHE C 387
ILE C 397
LEU C 421
1.27A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE C 325
ILE C 345
LEU C 499
GLY C 512
LEU C 374
1.40A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE C 800
LEU C 920
GLY C1041
ALA C1038
LEU C 927
1.39A16.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE C 800
LEU C 920
GLY C1041
ALA C1038
LEU C 927
1.45A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 500
TYR B 410
PHE B 387
ILE B 397
LEU B 421
1.57A16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6cs2 ACE2
(Homo
sapiens)		5 / 12
TYR D 510
TYR D 515
PHE D 512
ARG D 460
LEU D 503
1.64A21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		5 / 12
PHE E 338
ILE E 358
LEU E 513
GLY E 526
LEU E 387
1.64A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6m17 ACE2
(Homo
sapiens)		5 / 12
TYR B 633
ILE B 622
LEU B 717
ALA B 632
LEU B 628
1.28A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6m17 ACE2
(Homo
sapiens)		5 / 12
TYR B 633
ILE B 622
LEU B 717
ALA B 632
LEU B 628
1.30A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
TYR C 509
SER C 504
ILE C  92
LEU C  96
LEU C  11
1.73A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE A 325
ILE A 345
LEU A 499
GLY A 512
LEU A 374
1.36A16.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
TYR A 200
PHE A 168
ILE A 231
TYR A 170
ARG C 357
1.61A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE C 338
ILE C 358
LEU C 513
GLY C 526
LEU C 387
1.36A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vw1 ACE2
(Homo
sapiens)		5 / 12
TYR A 158
ILE A 256
LEU A 248
ALA A 264
LEU A 267
1.71A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6vw1 ACE2
(Homo
sapiens)		5 / 12
ILE B 446
TYR B 515
LEU B 410
GLY B 399
ALA B 403
1.62A21.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
TYR B 279
SER B 294
PHE B 269
ILE B 270
LEU B 266
1.54A24.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vxs NSP3
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vxs NSP3
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C1055
ILE C 818
LEU C 938
ALA C1056
LEU C 945
1.32A15.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 818
LEU B 938
GLY B1059
ALA B1056
LEU B 945
1.39A15.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 338
ILE A 358
LEU A 513
GLY A 526
LEU A 387
1.43A15.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
TYR C 266
SER C  94
ILE C 210
LEU C 212
ALA C 264
1.63A15.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 12
TYR C 369
ILE C 434
TYR H  52
LEU C 513
LEU C 387
1.67A15.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 338
ILE C 358
LEU C 513
GLY C 526
LEU C 387
1.77A15.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 12
TYR C 369
ILE C 434
TYR H  52
LEU C 513
LEU C 387
1.69A15.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w4h NSP16
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.60A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w6y NSP3
(SARS-CoV-2)		5 / 12
TYR B 113
SER B 111
ILE B 106
ALA B 112
LEU B 127
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w6y NSP3
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w6y NSP3
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.49A
None
None
None
None
AMP  A 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER C6943
ILE C6969
LEU C7004
HIS C7023
ALA C6976
1.53A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.56A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.66A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.70A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.66A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w75 NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.71A16.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR A 305
ARG A 183
LEU A 234
GLY A 209
LEU A 185
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR B 305
ARG B 183
LEU B 234
GLY B 209
LEU B 185
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
TYR C 305
ARG C 183
LEU C 234
GLY C 209
LEU C 185
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wcf NSP3
(SARS-CoV-2)		5 / 12
PHE A 116
LEU A 126
GLY A  78
ALA A 112
LEU A 109
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wcf NSP3
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wen NSP3
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wey NSP3
(SARS-CoV-2)		5 / 12
TYR A 317
SER A 315
ILE A 310
ALA A 316
LEU A 331
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wey NSP3
(SARS-CoV-2)		5 / 12
PHE A 320
LEU A 330
GLY A 282
ALA A 316
LEU A 313
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wey NSP3
(SARS-CoV-2)		5 / 12
SER A 343
ILE A 310
TYR A 317
HIS A 342
ALA A 333
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 318
TYR B 333
PHE B 314
ILE A 337
ALA A 313
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR F 333
PHE F 314
ILE E 337
GLY E 316
ALA E 313
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR C 333
PHE C 314
ILE D 337
GLY D 316
ALA D 313
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D 315
ILE C 304
HIS C 356
GLY D 321
LEU C 339
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR A 333
PHE A 314
ILE B 337
GLY B 316
ALA B 313
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR E 333
PHE E 314
ILE F 337
GLY F 316
ALA F 313
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR D 333
PHE D 314
ILE C 337
GLY C 316
ALA C 313
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 318
TYR F 333
PHE F 314
ILE E 337
ALA E 313
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
TYR B 333
PHE B 314
ILE A 337
GLY A 316
ALA A 313
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C 315
ILE D 304
HIS D 356
GLY C 321
LEU D 339
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER C6943
ILE C6969
LEU C7004
HIS C7023
ALA C6976
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.56A
FMT  A7108 (-2.6A)
None
None
None
FMT  A7108 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C6943
ILE C6969
LEU C7004
HIS C7023
ALA C6976
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE C6985
ILE C6955
LEU C6959
ALA C6966
LEU C6924
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wkq NSP16
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.46A
None
None
None
None
APR  A 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER C 139
ILE C 106
TYR C 113
HIS C 138
ALA C 129
1.44A
None
None
None
None
APR  C 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.50A
None
None
None
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER D 139
ILE D 106
TYR D 113
HIS D 138
ALA D 129
1.45A
None
None
None
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
PHE A6985
ILE A6955
LEU A6959
ALA A6966
LEU A6924
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6943
ILE A6969
LEU A7004
HIS A7023
ALA A6976
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wqd NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ILE D 120
ARG D 190
LEU D 128
ALA D 152
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
TYR D 149
SER D 151
ILE D 107
LEU C  60
ALA D 150
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
TYR D 149
SER D 151
ILE D 107
LEU C  60
ALA D 150
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 338
ILE A 358
LEU A 513
GLY A 526
LEU A 387
1.73A
None
None
None
None
DMS  A 905 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 338
ILE E 358
LEU E 513
GLY E 526
LEU E 387
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 338
ILE E 358
LEU E 513
GLY E 526
LEU E 387
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 338
ILE A 358
LEU A 513
GLY A 526
LEU A 387
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 338
ILE E 358
LEU E 513
GLY E 526
LEU E 387
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER E 139
ILE E 106
TYR E 113
HIS E 138
ALA E 129
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C 139
ILE C 106
TYR C 113
HIS C 138
ALA C 129
1.50A
None
EDO  C 208 ( 4.2A)
None
EDO  C 208 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER D 139
ILE D 106
TYR D 113
HIS D 138
ALA D 129
1.50A
None
EDO  D 204 (-4.2A)
None
EDO  D 204 (-4.1A)
EDO  D 205 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
TYR C 113
SER C 111
ILE C 106
ALA C 112
LEU C 127
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER D 139
ILE D 106
TYR D 113
HIS D 138
ALA D 129
1.41A
None
None
None
None
APR  D 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.46A
None
EDO  A 204 ( 4.0A)
None
EDO  A 204 ( 4.0A)
APR  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C 139
ILE C 106
TYR C 113
HIS C 138
ALA C 129
1.42A
None
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER E 139
ILE E 106
TYR E 113
HIS E 138
ALA E 129
1.37A
None
None
None
None
APR  E 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.42A
None
None
None
None
APR  B 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER C 139
ILE C 106
TYR C 113
HIS C 138
ALA C 129
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER A 139
ILE A 106
TYR A 113
HIS A 138
ALA A 129
1.47A
None
EDO  A 205 ( 4.3A)
None
EDO  A 205 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
TYR C 113
SER C 111
ILE C 106
ALA C 112
LEU C 127
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
SER B 139
ILE B 106
TYR B 113
HIS B 138
ALA B 129
1.53A
None
EDO  B 204 ( 4.5A)
None
EDO  B 204 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
TYR D 149
SER D 151
ILE D 107
LEU C  60
ALA D 150
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		7btf NSP8
(SARS-CoV-2)		5 / 12
SER D 151
ILE D 120
ARG D 190
LEU D 128
ALA D 152
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
TYR D 149
SER D 151
ILE D 107
LEU C  56
ALA D 150
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 692
PHE A 480
ILE A 579
LEU A 575
ALA A 690
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
SER A 692
PHE A 480
ILE A 579
LEU A 575
ALA A 690
1.67A
None