Ligand ID: KTR


Drugbank ID:
DB00465
(Ketorolac)


Indication:
For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.

Get human targets for KTR in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'KTR'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		1ssk NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 5
THR A 143
GLY A  49
VAL A 111
PRO A  51
1.33A19.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 5
THR A 304
GLY B 124
VAL B 125
TYR B 118
1.62A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		1x7q BETA-2-MICROGLOBULIN
(Homo
sapiens)		5 / 12
ILE B  35
TYR B  66
LEU B  39
LEU B  23
TYR B  10
1.55A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		1x7q HLA, A-11
(Homo
sapiens)		5 / 12
TYR A  99
GLU A  63
TYR A 171
LEU A 168
TYR A 159
1.61A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 5
THR A 304
GLY B 124
VAL B 125
TYR B 118
1.65A21.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
MET G 323
THR G 330
LEU H 340
PHE H 308
LEU H 354
1.75A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 5
THR D  23
VAL D  16
PRO D  44
TYR D  43
1.75A13.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		2cme -
(-)		4 / 5
THR E  23
VAL E  16
PRO E  44
TYR E  43
1.80A13.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
TYR B 265
ILE C 223
THR C 198
LEU C 200
TYR B 269
1.66A19.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		2gri NSP3
(SARSr)		5 / 12
TYR A  43
GLU A  60
THR A  65
LEU A  66
LEU A  28
1.41A21.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		2ofz NUCLEOCAPSID PROTEIN
(SARS-COV
Tor2)		4 / 5
THR A 166
GLY A  72
VAL A 134
PRO A  74
1.48A18.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 5
GLY A  73
VAL A  78
PRO A  80
TYR A  47
1.76A22.53
SAH  A1300 (-4.1A)
None
SAH  A1300 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 291
TYR B 279
THR B 276
LEU B 444
LEU B 240
1.60A14.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 5
THR A 304
GLY B 124
VAL B 125
TYR B 118
1.60A22.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		5 / 12
LYS F   0
GLU D  55
TYR D 171
LEU D 168
ARG A 131
1.74A15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		3i6g HLA, A-2
(Homo
sapiens)		5 / 12
TYR D  99
GLU D  63
TYR D 171
LEU D 168
TYR D 159
1.56A22.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 5
THR A 304
GLY B 124
VAL B 125
TYR B 118
1.65A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE B 291
TYR B 279
THR B 276
LEU B 444
LEU B 240
1.69A14.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		3vb6 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 5
THR B 304
GLY A 124
VAL A 125
TYR A 118
1.58A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 5
THR B 437
VAL B 398
PRO B 393
TYR B 370
1.18A20.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 5
THR B 437
VAL B 398
PRO B 393
TYR B 370
1.28A20.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 5
THR D 437
VAL D 398
PRO D 393
TYR D 370
1.31A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
THR B 169
LEU B 173
PHE B 128
LEU B 133
TYR B 137
1.78A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
TYR A 266
TYR A  41
THR A 215
PHE A  59
ARG A  48
1.78A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		5x5c S PROTEIN
(MERS-CoV)		4 / 5
THR B 579
GLY C  61
PRO C  59
TYR C  64
1.79A12.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
THR B 869
GLY B 873
PRO C1051
TYR C1029
1.62A16.31
THR  B 869 ( 0.8A)
GLY  B 873 ( 0.0A)
PRO  C1051 ( 1.1A)
TYR  C1029 ( 1.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
TYR B 266
TYR B  41
THR B 215
PHE B  59
ARG B  48
1.74A8.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
THR C 869
GLY C 871
VAL C 767
TYR A1029
1.74A14.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6ack ACE2
(Homo
sapiens)		5 / 12
TYR D 587
TYR D 279
THR D 276
LEU D 444
LEU D 240
1.57A14.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
GLY C  77
VAL C  25
PRO C  28
TYR C  30
1.67A14.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
GLY B  77
VAL B  25
PRO B  28
TYR B  30
1.54A14.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6iex BETA-2-MICROGLOBULIN
(Homo
sapiens)		5 / 12
ILE B  35
TYR B  66
LEU B  39
LEU B  23
TYR B  10
1.50A23.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 12
TYR A  99
GLU A  63
TYR A 171
LEU A 168
TYR A 159
1.60A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6jyt HELICASE
(SARSr-CoV)		4 / 5
THR B 566
GLY B 285
PRO B 283
TYR B 457
1.46A20.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6kl2 NUCLEOPROTEIN
(MERS-CoV)		4 / 5
THR A 154
GLY A  62
VAL A 123
PRO A  64
1.46A18.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY B 404
VAL B 503
PRO B 507
TYR B 495
1.55A20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		5 / 12
GLU E 406
ILE E 402
TYR E 495
LEU E 452
LEU E 492
1.54A22.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 5
THR C 304
GLY A 124
VAL A 125
TYR A 118
1.75A23.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR C 166
GLY C  72
VAL C 134
PRO C  74
1.46A18.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6m71 NSP12
(SARS-CoV-2)		4 / 5
GLY A 352
VAL A 299
PRO A 296
TYR A 294
1.79A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6m71 NSP12
(SARS-CoV-2)		4 / 5
GLY A 230
VAL A 202
PRO A 232
TYR A 289
1.09A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
TYR C 266
TYR C  41
PHE C  59
TYR C  53
ARG C  48
1.55A8.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6nus NSP12
(SARSr-CoV)		4 / 5
GLY A 230
VAL A 202
PRO A 232
TYR A 289
1.14A15.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY B 404
VAL B 503
PRO B 507
TYR B 495
1.58A13.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY E 404
VAL E 503
PRO E 507
TYR E 495
1.69A21.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6vw1 ACE2
(Homo
sapiens)		5 / 12
ILE B 291
TYR B 279
THR B 276
LEU B 444
LEU B 240
1.67A14.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 5
THR C 165
GLY C  71
VAL C 133
PRO C  73
1.46A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 5
THR H 100
GLY H  95
VAL H 102
TYR L  96
1.64A18.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 5
GLY C 404
VAL C 503
PRO C 507
TYR C 495
1.68A19.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
GLU C 406
ILE C 402
TYR C 495
LEU C 452
LEU C 492
1.69A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ILE C 123
THR C 168
LEU C 172
PHE C 127
LEU C 132
1.76A18.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6wcf NSP3
(SARS-CoV-2)		5 / 12
TYR A   9
ILE A  23
LEU A 126
LEU A 164
TYR A 161
1.78A24.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR C 165
GLY C  71
VAL C 133
PRO C  73
1.51A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR A 165
GLY A  71
VAL A 133
PRO A  73
1.44A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR B 165
GLY B  71
VAL B 133
PRO B  73
1.49A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR D 165
GLY D  71
VAL D 133
PRO D  67
1.80A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 5
THR D 165
GLY D  71
VAL D 133
PRO D  73
1.53A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
TYR A   9
ILE A  23
LEU A 126
LEU A 164
TYR A 161
1.73A24.24
None
APR  A 201 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 5
THR A 125
GLY A  31
VAL A  93
PRO A  33
1.57A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 5
THR A 125
GLY A  31
VAL A  93
PRO A  27
1.59A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
THR B 104
GLY B  99
VAL B 108
TYR C 102
1.40A21.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
THR H 104
GLY H  99
VAL H 108
TYR L 102
1.53A21.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY E 404
VAL E 503
PRO E 507
TYR E 495
1.71A20.65
DMS  E 902 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY A 404
VAL A 503
PRO A 507
TYR A 495
1.54A20.65
DMS  A 903 (-3.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 5
THR H 104
GLY H  99
VAL H 108
TYR L 102
1.54A21.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 5
THR H 104
GLY H  99
VAL H 108
TYR L 102
1.53A21.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY E 404
VAL E 503
PRO E 507
TYR E 495
1.71A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		4 / 5
THR B 104
GLY B  99
VAL B 108
TYR C 102
1.52A21.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLY A 404
VAL A 503
PRO A 507
TYR A 495
1.71A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		7btf NSP12
(SARS-CoV-2)		4 / 5
GLY A 352
VAL A 299
PRO A 296
TYR A 294
1.71A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		7btf NSP12
(SARS-CoV-2)		4 / 5
GLY A 230
VAL A 202
PRO A 232
TYR A 289
1.07A15.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 5
GLY A 230
VAL A 202
PRO A 232
TYR A 289
1.11A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 5
GLY A 230
VAL A 202
PRO A 232
TYR A 289
1.15A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 5
GLY A 352
VAL A 353
PRO A 296
TYR A 294
1.79A15.35
None