Ligand ID: 9RA


Drugbank ID:
DB00307
(Bexarotene)


Indication:
Used orally for the treatment of skin manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to at least one prior systemic therapy. Also used topically for the treatment of skin lesions in early (stage IA and IB) CTCL in patients who experience refractory or persistent disease with the use of other therapies or are intolerant of other therapies.

Get human targets for 9RA in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '9RA'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
ILE B 136
PHE B 140
HIS B 164
0.88A21.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.32A21.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
ALA C 316
GLN C 320
LEU C 291
ILE C 200
LEU C 342
1.34A22.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		6 / 12
ILE E 111
ALA E 107
ALA E 155
ILE E 124
LEU E 108
VAL A  63
1.77A20.09
None
None
None
GOL  A2003 (-4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2ajf SPIKE PROTEIN
(SARSr-CoV)		5 / 12
GLN E 401
ILE E 405
LEU E 412
ALA E 398
VAL E 337
1.33A20.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2ajf ACE2
(Homo
sapiens)		5 / 12
ALA A 443
GLN A 442
LEU A 439
ILE A 436
LEU A 444
1.13A17.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.32A21.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2amq 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.38A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
ALA B 135
GLN B 139
LEU B 110
ILE B 154
LEU B 161
1.32A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
ILE A 152
PHE A 128
HIS A 172
1.23A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
GLN A 238
LEU A 235
LEU A 200
ALA A 205
ILE A 223
1.41A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
ALA A  65
ALA A  65
ARG A  62
LEU A  66
ALA A  65
1.18A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		3 / 3
ILE B 321
PHE B 315
HIS B 335
0.89A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.43A21.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.43A20.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		2zu5 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.29A21.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3bgf F26G19 FAB
(Mus
musculus)		5 / 12
ALA C  50
ALA C  51
LEU C  33
ILE C  29
LEU B 100
1.17A20.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
ILE B 291
PHE B 428
HIS B 540
1.01A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B 443
GLN B 442
LEU B 439
ILE B 436
LEU B 444
1.15A17.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.43A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.39A21.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ALA D  43
LEU D  42
LEU D  29
ALA D  30
VAL D 110
1.44A19.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA B  70
GLN B  69
LEU B  67
ILE B  78
LEU B  89
1.33A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.28A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.42A21.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.41A20.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ALA B 150
ALA B 154
LEU B  88
ALA B  87
LEU B 133
1.44A21.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3sci ACE2
(Homo
sapiens)		3 / 3
ILE B 291
PHE B 428
HIS B 540
0.95A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3scj ACE2
(Homo
sapiens)		5 / 12
ALA A 443
GLN A 442
LEU A 439
ILE A 436
LEU A 444
1.06A17.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A 443
GLN A 442
LEU A 439
ILE A 436
LEU A 444
1.07A17.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
ILE B 291
PHE B 428
HIS B 540
0.86A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA A 443
GLN A 442
LEU A 439
LEU A 444
LEU A 595
1.37A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		3 / 3
ILE A 130
PHE A  79
HIS A 135
1.11A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA B  70
GLN B  69
LEU B  67
ILE B  78
LEU B  89
1.44A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
ILE B 338
PHE B 350
HIS B 314
1.11A19.92
G3A  B 606 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
ILE B 338
PHE B 350
HIS B 314
1.04A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
ILE C 338
PHE C 350
HIS C 314
1.12A19.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.55A21.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.48A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 253
LEU A 208
ALA A 210
LEU A 242
1.79A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA D 150
ALA D 154
LEU D  88
ALA D  87
VAL D  12
1.40A21.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		6 / 12
ILE A  33
ALA A  36
ALA A  32
LEU A  31
LEU A  37
VAL B  29
1.63A17.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		3 / 3
ILE C 704
PHE C 909
HIS C1030
1.16A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE A 674
ALA A 658
ALA A 676
LEU A 636
ILE A 637
1.30A10.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ALA A 753
ALA A 754
LEU A 843
VAL C 583
ILE C 584
1.18A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 652
ALA B 676
ALA B 658
LEU B 636
ALA B 639
1.19A10.04
ILE  B 652 ( 0.7A)
ALA  B 676 ( 0.0A)
ALA  B 658 ( 0.0A)
LEU  B 636 ( 0.6A)
ALA  B 639 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
ILE A 704
PHE A 909
HIS A1030
0.89A10.01
ILE  A 704 ( 0.7A)
PHE  A 909 ( 1.3A)
HIS  A1030 ( 1.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 656
ALA A 676
ALA A 658
ILE A 299
ALA A 639
1.10A10.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
ILE B 704
PHE B 909
HIS B1030
0.86A10.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
ILE C 704
PHE C 909
HIS C1030
1.06A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA C 874
LEU C 876
ALA C 875
VAL B 893
ILE B 891
1.35A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
ILE B 704
PHE B 909
HIS B1030
0.86A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ALA B 875
LEU B1016
LEU B 876
ALA B 866
VAL A1050
1.38A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6cs2 ACE2
(Homo
sapiens)		3 / 3
ILE D 544
PHE D 314
HIS D 535
1.14A17.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE C 674
ALA C 658
ALA C 676
LEU C 636
ILE C 637
1.19A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		6 / 12
ALA E 942
ALA E 944
LEU D 945
LEU E1186
ILE F1183
LEU F 948
1.79A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.55A22.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.50A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6lzg ACE2
(Homo
sapiens)		3 / 3
ILE A 291
PHE A 438
HIS A 417
0.96A16.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.49A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.57A22.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.54A21.38
DMS  A 401 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ALA A 282
ALA A 498
VAL A 103
ILE A 107
LEU A  88
1.34A15.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		6 / 12
ILE C 545
ALA C 271
ALA C 273
GLN C 274
PHE C 276
LEU C  77
1.70A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m17 ACE2
(Homo
sapiens)		5 / 12
ALA B 443
GLN B 442
LEU B 439
ILE B 436
LEU B 444
1.15A15.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m17 ACE2
(Homo
sapiens)		5 / 12
ALA B 714
ALA D 714
LEU D 642
ILE D 704
LEU D 722
1.35A14.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m1d ACE2
(Homo
sapiens)		3 / 3
ILE B 544
PHE B 314
HIS B 535
0.94A14.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 206
LEU B 253
LEU B 208
ALA B 210
LEU B 242
1.74A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.55A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA D 206
LEU D 253
LEU D 208
ALA D 210
LEU D 242
1.73A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA D 211
ALA D 210
LEU D 253
LEU D 208
ILE D 200
1.53A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.36A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C  70
GLN C  69
LEU C  67
ILE C  78
LEU C  89
1.42A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C 206
LEU C 253
LEU C 208
ALA C 210
LEU C 242
1.72A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C 211
ALA C 210
LEU C 253
LEU C 208
ILE C 200
1.49A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 211
ALA B 210
LEU B 253
LEU B 208
ILE B 200
1.50A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE C 213
ALA C 210
ALA C 211
ILE C 259
ALA C 206
1.56A22.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.59A22.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.50A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
LEU B  98
LEU B 117
ILE A 333
LEU B  91
1.56A14.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 579
ALA A 585
ILE A 696
PHE A 480
VAL A 693
1.42A14.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
ALA A 383
LEU B 103
LEU B 117
ILE A 333
1.58A14.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
ALA A 383
LEU B  98
LEU B 117
ILE A 333
1.73A14.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 150
VAL A 330
ILE B 107
LEU B  98
1.66A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 125
LEU B 122
VAL A 330
ILE B 107
LEU B  98
1.51A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
ALA A 690
VAL A 785
CYH A 464
LEU A 469
1.56A14.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
LEU A 387
ILE B 106
LEU A 270
1.53A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
ALA A 130
ILE A 244
LEU A 146
VAL A 182
1.42A14.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 632
ALA A 656
LEU A 663
ALA A 660
VAL A 315
1.51A14.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
LEU A 707
ALA A 777
VAL A 473
LEU A 731
1.59A14.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 526
GLN A 524
LEU A 527
PHE A 528
ALA A 490
1.60A14.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
ILE A 704
PHE A 909
HIS A1030
1.02A10.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 874
LEU A 876
ALA A 875
VAL B 893
ILE B 891
1.38A10.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 652
ALA B 676
ALA B 658
LEU B 636
ALA B 639
1.29A10.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 12
ALA B 152
ALA B 150
LEU A 387
ILE B 106
LEU A 270
1.38A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6nur NSP8
(SARSr-CoV)		5 / 12
ALA D 150
PHE D 147
ALA D 152
VAL D 186
CYH D 114
1.31A20.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 666
ALA A 694
ALA A 672
LEU A 650
ALA A 653
1.32A9.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA B 892
LEU B 894
ALA B 893
VAL A 911
ILE A 909
1.30A9.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ALA A 129
ALA A 134
LEU A 109
LEU A 126
VAL A 144
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B 124
LEU B 122
LEU B  53
VAL B  30
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 122
LEU A  53
VAL A  30
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA C 892
LEU C 894
ALA C 893
VAL B 911
ILE B 909
1.38A9.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA C 892
LEU C 894
ALA C 893
VAL B 911
ILE B 909
1.26A9.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
GLN C 414
ILE C 418
LEU C 425
ALA C 411
VAL C 350
1.57A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
ALA C 419
GLN C 414
ILE C 402
LEU C 425
ALA C 411
1.46A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
ALA C 419
GLN C 414
ILE C 402
LEU C 425
VAL C 510
1.57A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w4b NSP9
(SARS-CoV-2)		5 / 12
GLN B  12
LEU B  30
LEU B  10
ILE B  92
LEU B  89
1.40A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 NSP10
(SARS-CoV-2)		5 / 12
ALA B4276
ALA B4277
LEU B4365
ALA B4279
CYH B4327
1.73A
None
None
None
None
ZN  B4403 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A7023
1.57A
None
EDO  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE A6838
ALA A6843
GLN A6847
PHE A7043
LEU B4298
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6969
PHE A6947
HIS A6972
1.36A
None
EDO  A7102 (-3.8A)
KCX  A6935 (-4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ALA B4276
LEU B4365
ALA B4279
VAL A6902
CYH B4327
1.79A21.12
None
None
None
None
ZN  B4403 (-2.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A6867
1.28A
None
EDO  A7102 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 129
ALA B 134
LEU B 109
LEU B 126
VAL B 144
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B  50
ALA B  38
LEU B  53
VAL B  34
1.69A22.27
None
MES  B 201 ( 3.7A)
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B 124
LEU B 122
LEU B  53
VAL B  30
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A 124
LEU A 123
LEU A 153
ALA A 154
LEU A  93
1.78A21.89
None
None
None
AMP  A 201 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A  50
ALA A  38
LEU A  53
VAL A  34
1.70A22.27
AMP  A 201 ( 4.0A)
None
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B  38
LEU B  53
ALA B  50
VAL B  34
1.69A22.27
None
MES  B 201 ( 3.4A)
None
MES  B 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A 134
ALA A 129
LEU A 126
LEU A 109
VAL A  36
1.76A22.27
None
AMP  A 201 ( 3.4A)
AMP  A 201 ( 4.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE A  18
LEU A 169
PHE A 168
LEU A 164
VAL A 144
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 124
LEU B 123
LEU B 153
ALA B 154
LEU B  93
1.75A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  38
ALA B  39
ALA B  50
CYH B  81
LEU B  75
1.77A21.89
MES  B 201 ( 3.4A)
None
MES  B 201 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE A 131
ALA A 129
LEU A 127
PHE A 132
ALA A 134
1.70A22.27
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A  38
LEU A  53
ALA A  50
VAL A  34
1.69A22.27
AMP  A 201 ( 4.0A)
AMP  A 201 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE B  18
LEU B 169
PHE B 168
LEU B 164
VAL B 144
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A 129
ALA A 134
LEU A 109
LEU A 126
VAL A 144
1.62A
AMP  A 201 ( 3.4A)
None
None
AMP  A 201 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A6925
GLN A6956
LEU A6981
PHE A6985
LEU A6959
1.72A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6948
HIS A6867
1.53A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C7003
HIS C7023
1.53A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE A6838
ALA A6843
GLN A6847
PHE A7043
LEU B4298
1.59A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C7023
1.58A20.99
None
FMT  C7115 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE C6838
ALA C6843
GLN C6847
PHE C7043
LEU D4298
1.61A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A7003
HIS A7023
1.55A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE B4291
ALA D4273
LEU B4328
ALA B4276
VAL A6902
1.56A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A6867
1.26A20.99
None
SAM  A7102 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C6867
1.27A20.99
None
FMT  C7115 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE A6969
PHE A6947
HIS A6972
1.32A20.99
None
SAM  A7102 ( 4.8A)
FMT  A7103 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE B4291
GLN B4289
ALA D4271
VAL A6876
CYH B4294
1.79A20.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A7023
1.57A20.99
None
SAM  A7102 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE C6969
PHE C6947
HIS C6972
1.30A20.99
None
FMT  C7115 ( 3.5A)
FMT  C7107 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w75 NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6948
HIS C6867
1.51A20.99
None
FMT  C7115 ( 4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLN C 237
LEU C 234
LEU C 199
ALA C 204
ILE C 222
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ILE C 151
ALA C 149
ILE C 104
LEU C 152
ALA C  86
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 149
ALA A 153
LEU A  87
ALA A  86
LEU A 132
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 237
LEU A 234
LEU A 199
ALA A 204
ILE A 222
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA C 149
ALA C 153
LEU C  87
ALA C  86
LEU C 132
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA B 149
ALA B 153
LEU B  87
ALA B  86
LEU B 132
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
GLN B 237
LEU B 234
LEU B 199
ALA B 204
ILE B 222
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ILE B 151
ALA B 149
ILE B 104
LEU B 152
ALA B  86
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 151
ALA A 149
ILE A 104
LEU A 152
ALA A  86
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
GLN A  11
LEU A  29
LEU A   9
ILE A  91
LEU A  88
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ALA A  43
LEU A  42
ALA A  30
VAL A 110
LEU A 103
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ALA A  43
LEU A  42
LEU A  29
ALA A  30
VAL A 110
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ALA A  39
ALA A  38
ALA A  50
VAL A 100
LEU A 109
1.74A
MES  A 201 ( 4.7A)
MES  A 201 (-3.6A)
MES  A 201 ( 3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ALA A 129
ALA A 134
LEU A 109
LEU A 126
VAL A 144
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wcf NSP3
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 122
LEU A  53
VAL A  30
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wen NSP3
(SARS-CoV-2)		5 / 12
ALA A 124
LEU A 123
LEU A 153
ALA A 154
LEU A  93
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wey NSP3
(SARS-CoV-2)		5 / 12
ILE A 222
LEU A 373
PHE A 372
LEU A 368
VAL A 348
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wey NSP3
(SARS-CoV-2)		5 / 12
ALA A 328
LEU A 327
LEU A 357
ALA A 358
LEU A 297
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  48
LEU A  40
ALA A  42
VAL A  12
LEU B  98
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU A  71
ARG B  96
LEU B  95
VAL A  58
LEU A  20
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP8
(SARS-CoV-2)		5 / 12
ALA B 150
PHE B 147
ALA B 152
VAL B 186
CYH B 114
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
VAL B 186
ILE B 132
CYH B 114
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
GLN B  88
LEU B  91
LEU A  17
ILE A  39
LEU B 103
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA B 150
ALA B 152
VAL A   6
ILE A  39
LEU A  56
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA C 305
GLN C 303
LEU C 352
VAL C 270
ILE C 292
1.61A
 CL  C 401 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA F 305
GLN F 303
LEU F 352
VAL F 270
ILE F 292
1.63A
 CL  F 401 ( 4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA D 305
GLN D 303
LEU D 352
VAL D 270
ILE D 292
1.63A
 CL  D 401 ( 4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA A 305
GLN A 303
LEU A 352
VAL A 270
ILE A 292
1.59A
 CL  A 401 ( 4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ALA E 305
GLN E 303
LEU E 352
VAL E 270
ILE E 292
1.68A
 CL  E 401 ( 4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6969
PHE A6947
HIS A6972
1.32A
None
SAH  A7102 (-4.7A)
FMT  A7103 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6951
PHE A6954
HIS A6867
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE C6969
PHE C6947
HIS C6972
1.30A
None
SAH  C7102 (-4.6A)
FMT  C7104 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A6867
1.25A
None
SAH  A7102 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C6867
1.27A
None
SAH  C7102 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C7023
1.56A
None
SAH  C7102 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A7023
1.56A
None
SAH  A7102 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE C6838
ALA C6843
GLN C6847
PHE C7043
LEU D4298
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt NSP10
(SARS-CoV-2)		3 / 3
ILE D4291
PHE B4272
HIS D4333
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE A6838
ALA A6843
GLN A6847
PHE A7043
LEU B4298
1.61A
None
None
None
None
FMT  B4403 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A7003
HIS A7023
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE D4291
ALA B4273
LEU D4328
ALA D4276
VAL C6902
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE B4291
ALA D4273
LEU B4328
ALA B4276
VAL A6902
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C7003
HIS C7023
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
ILE A  84
PHE A 110
HIS A 145
1.58A
None
None
ZN  A 201 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
ILE C  84
PHE C 110
HIS C 145
1.52A
None
None
ZN  C 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
ILE B  84
PHE B 110
HIS B 145
1.58A
None
None
ZN  B 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
ILE D  84
PHE D 110
HIS D 145
1.58A
None
None
ZN  D 202 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE C6838
ALA C6843
GLN C6847
PHE C7043
LEU D4298
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6948
HIS C6867
1.50A
None
FMT  C7105 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE B4291
ALA D4273
LEU B4328
ALA B4276
VAL A6902
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6951
PHE C6954
HIS C6867
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP10
(SARS-CoV-2)		3 / 3
ILE D4291
PHE B4272
HIS D4333
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C7023
1.57A
None
FMT  C7105 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6951
PHE C6947
HIS C6867
1.34A
None
FMT  C7105 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C6947
HIS C6867
1.27A
None
FMT  C7105 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A6867
1.26A
None
SFG  A7103 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE D4291
ALA B4273
LEU D4328
ALA D4276
VAL C6902
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6948
HIS A6867
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE A6969
PHE A6947
HIS A6972
1.32A
None
SFG  A7103 ( 4.8A)
FMT  A7105 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A7023
1.56A
None
SFG  A7103 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6967
PHE C7003
HIS C7023
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A7003
HIS A7023
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 12
ILE A6838
ALA A6843
GLN A6847
PHE A7043
LEU B4298
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wkq NSP16
(SARS-CoV-2)		3 / 3
ILE C6969
PHE C6947
HIS C6972
1.31A
None
FMT  C7105 ( 3.5A)
FMT  C7104 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
ILE A 100
PHE A 124
HIS A  96
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
ILE B 100
PHE B 124
HIS B  96
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A  39
ALA A  38
ALA A  50
VAL A 100
LEU A 109
1.74A
None
APR  A 201 (-3.5A)
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE C  23
ALA C 124
LEU C 122
LEU C  53
VAL C  30
1.58A
APR  C 201 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B 124
LEU B 122
LEU B  53
VAL B  30
1.58A
APR  B 201 (-3.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 122
LEU A  53
VAL A  30
1.59A
APR  A 201 (-4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B  39
ALA B  38
ALA B  50
VAL B 100
LEU B 109
1.71A
None
APR  B 201 (-3.3A)
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C 129
ALA C 134
LEU C 109
LEU C 126
VAL C 144
1.58A
APR  C 201 (-3.7A)
None
None
APR  C 201 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA C  39
ALA C  38
ALA C  50
VAL C 100
LEU C 109
1.72A
None
APR  C 201 (-3.4A)
APR  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA D 129
ALA D 134
LEU D 109
LEU D 126
VAL D 144
1.61A
APR  D 201 (-3.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE D  23
ALA D 124
LEU D 122
LEU D  53
VAL D  30
1.58A
APR  D 201 (-3.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6969
PHE A6947
HIS A6972
1.27A
None
SAH  A7101 ( 4.8A)
GTA  A7102 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A7023
1.56A
None
SAH  A7101 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A7003
HIS A7023
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
ILE A6967
PHE A6947
HIS A6867
1.30A
None
SAH  A7101 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
ILE A6838
ALA A6843
GLN A6847
PHE A7043
LEU B4298
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ALA B 150
PHE B 147
ALA B 152
VAL B 186
CYH B 114
1.47A
EDO  B 302 (-3.7A)
None
EDO  B 302 ( 4.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		6 / 12
ALA D 152
ALA D 150
LEU D 153
VAL D 186
ILE D 132
CYH D 114
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
PHE D 147
ALA D 152
VAL D 186
CYH D 114
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ALA B 102
ALA B 150
LEU B 103
ILE B 119
LEU B 128
1.65A
EDO  B 302 ( 4.2A)
EDO  B 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ALA D 102
ALA D 150
LEU D 103
ILE D 119
LEU D 128
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
VAL B 186
ILE B 132
CYH B 114
1.28A
EDO  B 302 ( 4.3A)
EDO  B 302 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
GLN D  88
LEU D  91
LEU C  17
ILE C  39
LEU D 103
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
ILE A 151
ALA A 149
ILE A 104
LEU A 152
ALA A  86
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
GLN A 237
LEU A 234
LEU A 199
ALA A 204
ILE A 222
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
ALA A 149
ALA A 153
LEU A  87
ALA A  86
LEU A 132
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.48A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 253
LEU A 208
ALA A 210
LEU A 242
1.79A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.58A21.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA D 152
ALA D 150
VAL D 186
ILE D 132
CYH D 114
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA D 150
PHE D 147
ALA D 152
VAL D 186
CYH D 114
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA B 150
PHE B 147
ALA B 152
VAL B 186
CYH B 114
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
LEU B 153
VAL B 186
ILE B 132
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA B 102
ALA B 150
LEU B 103
ILE B 119
LEU B 128
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
VAL B 186
ILE B 132
CYH B 114
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
GLN B  88
LEU B  91
LEU A  17
ILE A  39
LEU B 103
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		3 / 3
ILE A  44
PHE A  70
HIS A 105
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 419
GLN A 414
ILE A 402
LEU A 425
VAL A 510
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
VAL E 510
1.53A
None
MLI  E 908 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
ALA E 411
1.45A
None
MLI  E 908 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN E 414
ILE E 418
LEU E 425
ALA E 411
VAL E 350
1.47A
MLI  E 908 ( 4.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 414
ILE A 418
LEU A 425
ALA A 411
VAL A 350
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 419
GLN A 414
ILE A 402
LEU A 425
ALA A 411
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yla LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		3 / 3
ILE C  34
PHE A 392
HIS A 519
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN E 414
ILE E 418
LEU E 425
ALA E 411
VAL E 350
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
VAL E 510
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
ALA E 411
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 419
GLN A 414
ILE A 402
LEU A 425
VAL A 510
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
VAL E 510
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA E 419
GLN E 414
ILE E 402
LEU E 425
ALA E 411
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ALA A 419
GLN A 414
ILE A 402
LEU A 425
ALA A 411
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 414
ILE A 418
LEU A 425
ALA A 411
VAL A 350
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.51A
None
None
None
None
PEG  A 405 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA C  50
ALA C  39
LEU C  43
LEU C  53
VAL C  34
1.69A
None
None
None
None
EDO  C 207 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE D  23
ALA D  38
LEU D  53
ALA D  50
VAL D  34
1.60A
EDO  D 208 (-4.0A)
EDO  D 205 (-3.5A)
None
EDO  D 206 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  18
LEU A 169
PHE A 168
LEU A 164
VAL A 144
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA D  50
ALA D  39
LEU D  43
LEU D  53
VAL D  34
1.71A
EDO  D 206 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE D  23
ALA D 124
LEU D 122
LEU D  53
VAL D  30
1.62A
EDO  D 208 (-4.0A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE E  18
LEU E 169
PHE E 168
LEU E 164
VAL E 144
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  23
ALA C 124
LEU C 122
LEU C  53
VAL C  30
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  18
LEU C 169
PHE C 168
LEU C 164
VAL C 144
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE D  18
LEU D 169
PHE D 168
LEU D 164
VAL D 144
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 122
LEU A  53
VAL A  30
1.61A
APR  A 201 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE B  23
ALA B 124
LEU B 122
LEU B  53
VAL B  30
1.61A
APR  B 201 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE E  18
LEU E 169
PHE E 168
LEU E 164
VAL E 144
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  39
ALA E  38
ALA E  50
VAL E 100
LEU E 109
1.74A
None
APR  E 201 (-3.3A)
APR  E 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  23
ALA C 124
LEU C 122
LEU C  53
VAL C  30
1.60A
APR  C 201 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  18
LEU A 169
PHE A 168
LEU A 164
VAL A 144
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE D  23
ALA D 124
LEU D 122
LEU D  53
VAL D  30
1.62A
APR  D 201 (-3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE D  18
LEU D 169
PHE D 168
LEU D 164
VAL D 144
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  18
LEU C 169
PHE C 168
LEU C 164
VAL C 144
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  38
ALA A  39
LEU A 127
CYH A  81
LEU A  75
1.73A
APR  A 201 (-3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE B  18
LEU B 169
PHE B 168
LEU B 164
VAL B 144
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  18
LEU A 169
PHE A 168
LEU A 164
VAL A 144
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  18
LEU C 169
PHE C 168
LEU C 164
VAL C 144
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 122
LEU A  53
VAL A  30
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE C  23
ALA C 124
LEU C 122
LEU C  53
VAL C  30
1.60A
EDO  C 206 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE B 131
ALA B 129
LEU B 127
PHE B 132
ALA B 134
1.60A
None
None
None
None
EDO  B 204 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP8
(SARS-CoV-2)		5 / 12
ALA D 152
ALA D 150
VAL D 186
ILE D 132
CYH D 114
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
LEU B  98
LEU B 117
ILE A 333
LEU B  91
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
ALA A 383
LEU B 103
LEU B 117
ILE A 333
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP8
(SARS-CoV-2)		5 / 12
ALA D 102
ALA D 150
LEU D 103
ILE D 119
LEU D 128
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 579
ALA A 585
ILE A 696
PHE A 480
VAL A 693
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
ALA D 152
VAL D 186
ILE D 132
CYH D 114
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
LEU A 387
ILE B 106
LEU A 270
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 526
GLN A 524
LEU A 527
PHE A 528
ALA A 490
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
ALA A 690
VAL A 785
CYH A 464
LEU A 469
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
PHE D 147
ALA D 152
VAL D 186
CYH D 114
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
ALA A 130
ILE A 244
LEU A 146
VAL A 182
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
ALA D 152
VAL C   6
ILE C  39
LEU C  56
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
LEU D 128
ARG D 190
ALA D 152
LEU C  60
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A   4
GLN A   5
LEU A   8
PHE A   7
CYH A  54
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7btf NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
LEU D 103
ALA D 102
ILE D 119
LEU D 128
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 211
ALA A 210
LEU A 253
LEU A 208
ILE A 200
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A  70
GLN A  69
LEU A  67
ILE A  78
LEU A  89
1.41A
DMS  A 403 ( 4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A 213
ALA A 210
ALA A 211
ILE A 259
ALA A 206
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
ALA A 690
VAL A 785
CYH A 464
LEU A 469
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
LEU A 387
ALA B 150
ILE B 156
LEU B 189
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 382
ALA A 383
LEU B 103
LEU B 117
ILE A 333
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A  34
LEU A 240
ALA A 125
VAL A  42
LEU A 708
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 526
GLN A 524
LEU A 527
PHE A 528
ALA A 490
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
LEU A 387
ILE B 106
LEU A 270
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA D 102
LEU C  60
ALA D 150
VAL C   6
LEU D  95
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
ALA D 152
VAL C   6
ILE C  39
LEU C  56
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP8
(SARS-CoV-2)		5 / 12
ALA D 150
PHE D 147
ALA D 152
VAL D 186
CYH D 114
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP8
(SARS-CoV-2)		5 / 12
ILE D 106
ALA D 150
LEU D 128
ILE D 119
ALA D 152
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
ALA A 130
ILE A 244
LEU A 146
VAL A 182
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 863
LEU A 883
ALA A 866
VAL A 848
LEU A 891
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
LEU C  40
ALA C  42
VAL C  12
LEU D  98
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 579
ALA A 585
ILE A 696
PHE A 480
VAL A 693
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 126
ALA B 125
LEU A 387
LEU B 189
VAL B 186
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 185
GLN A 184
ARG A 183
LEU A 186
VAL A 128
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 863
LEU A 883
ALA A 866
VAL A 848
LEU A 891
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
LEU A 707
ALA A 777
VAL A 473
LEU A 731
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 379
ALA A 383
LEU B 103
VAL A 335
LEU B  95
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
ALA A 690
VAL A 785
CYH A 464
LEU A 469
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 579
ALA A 585
ILE A 696
PHE A 480
VAL A 693
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 526
GLN A 524
LEU A 527
PHE A 528
ALA A 490
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 152
ALA B 150
LEU A 387
ILE B 106
LEU A 270
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
NSP8
(SARS-CoV-2)		6 / 12
ALA A 382
ALA A 383
LEU B 103
LEU B 117
ILE A 333
LEU B  95
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
ALA A 130
ILE A 244
LEU A 146
VAL A 182
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 185
GLN A 184
ARG A 183
LEU A 186
VAL A 128
1.67A
None