Ligand ID: DSF


Drugbank ID:
DB01189
(Desflurane)


Indication:
For use as an inhalation agent for induction and/or maintenance of anesthesia for inpatient and outpatient surgery in adults.

Get human targets for DSF in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'DSF'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		2ajf SPIKE PROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.03A18.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 9
ILE F 358
ILE E 321
TYR E 334
THR E 333
ILE F 338
1.76A15.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		2cme HYPOTHETICAL PROTEIN
5
(SARSr)		4 / 8
PRO H  40
VAL G  42
THR H  23
ILE H  24
1.34A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		2dd8 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR S 410
ILE S 397
ILE S 405
VAL S 496
1.03A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		2dd8 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR S 410
ILE S 397
ILE S 405
VAL S 496
TYR S 481
1.76A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		2ghw SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR C 410
ILE C 397
ILE C 405
VAL C 496
1.02A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 9
PRO A 343
ILE A 322
ILE A 295
VAL A 320
ILE A 305
1.35A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 10
PRO A 343
ILE A 322
ILE A 295
VAL A 320
ILE A 305
1.36A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2jzd REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
ILE A 560
ILE A 556
MET A 557
TYR A 583
ILE A 569
1.43A19.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		2kqv NSP3
(SARSr-CoV)		5 / 9
TYR A  61
ILE A  27
MET A  35
ILE A  47
ILE A  45
1.71A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2kqv NSP3
(SARSr-CoV)		5 / 10
ILE A  34
MET A  84
VAL A  31
TYR A  61
ILE A  86
1.70A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
TYR A 193
ILE A 305
VAL A 320
ILE A 295
ILE A 327
1.70A23.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
TYR A 193
ILE A 305
VAL A 320
ILE A 295
ILE A 327
1.70A23.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
PRO E 343
ILE E 322
ILE E 295
VAL E 320
ILE E 305
1.17A23.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
PRO E 343
ILE E 322
ILE E 295
VAL E 320
ILE E 305
1.16A23.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2rnk REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
ILE A 560
ILE A 556
MET A 557
TYR A 583
ILE A 569
1.66A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		2wct NSP3
(SARSr-CoV)		5 / 10
ILE C 560
ILE C 556
MET C 557
TYR C 583
ILE C 569
1.58A21.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		4 / 8
TYR S 410
ILE S 397
ILE S 405
VAL S 496
1.07A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.03A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3d0g SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR F 410
ILE F 397
ILE F 405
VAL F 496
TYR F 481
1.73A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR E 481
TYR E 440
ILE E 405
VAL E 389
TYR E 491
1.74A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.08A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3d0i SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.08A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3d0i SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR E 481
TYR E 440
ILE E 405
VAL E 389
TYR E 491
1.77A19.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3sci SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR E 410
ILE E 397
ILE E 405
VAL E 496
TYR E 481
1.77A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3sci SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.03A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3scj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR E 410
ILE E 397
ILE E 405
VAL E 496
TYR E 481
1.76A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3scj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
0.98A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3sck SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR E 481
TYR E 440
ILE E 405
VAL E 389
TYR E 491
1.74A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3sck SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.06A18.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR F 410
ILE F 397
ILE F 405
VAL F 496
1.02A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR F 410
ILE F 397
ILE F 405
VAL F 496
TYR F 481
1.72A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		4mm3 UBIQUITIN
(Homo
sapiens)		5 / 9
ILE A  30
ILE A  36
VAL A   5
THR A   7
ILE A  13
1.54A13.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		4mm3 UBIQUITIN
(Homo
sapiens)		5 / 10
ILE A  30
ILE A  36
VAL A   5
THR A   7
ILE A  13
1.56A13.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		5e6j UBIQUITIN
(synthetic
construct)		5 / 9
ILE E  30
ILE E  36
VAL E   5
THR E   7
ILE E  13
1.48A12.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		5e6j UBIQUITIN
(synthetic
construct)		5 / 10
ILE E  30
ILE E  36
VAL E   5
THR E   7
ILE E  13
1.48A12.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
PRO P  23
TYR P  76
ILE P  81
VAL P 108
ILE P  38
1.70A16.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 9
PRO P  23
TYR P  76
ILE P  81
VAL P 108
ILE P  38
1.71A16.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR A 410
ILE A 397
ILE A 405
VAL A 496
TYR A 481
1.60A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR A 410
ILE A 397
ILE A 405
VAL A 496
TYR A 481
1.60A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
PRO A1051
TYR A1029
ILE A 891
VAL A 893
ILE A 702
1.49A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
PRO A1051
TYR A1029
ILE A 891
VAL A 893
ILE A 702
1.49A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 8
PRO A1051
TYR A1029
ILE A 891
VAL A 893
ILE A 702
1.49A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 10
PRO A1051
TYR A1029
ILE A 891
VAL A 893
ILE A 702
1.49A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		5x5c S PROTEIN
(MERS-CoV)		5 / 9
PRO B 476
TYR B 577
THR B 574
ILE B 573
ILE B 442
1.32A13.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		5x5c S PROTEIN
(MERS-CoV)		5 / 10
PRO B 476
TYR B 577
THR B 574
ILE B 573
ILE B 442
1.33A13.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		5x5f S PROTEIN
(MERS-CoV)		5 / 9
PRO A  59
TYR A  71
ILE A  69
TYR A  58
ILE A 333
1.66A13.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.62A15.47
PRO  B1051 ( 1.1A)
TYR  B1029 ( 1.3A)
ILE  B 891 ( 0.7A)
VAL  B 893 ( 0.6A)
ILE  B 702 ( 0.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.62A15.47
PRO  B1051 ( 1.1A)
TYR  B1029 ( 1.3A)
ILE  B 891 ( 0.7A)
VAL  B 893 ( 0.6A)
ILE  B 702 ( 0.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR C 646
TYR C 660
ILE C 674
VAL C 642
ILE C 652
1.46A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 8
TYR C 646
TYR C 660
ILE C 674
VAL C 642
ILE C 652
1.47A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR A 481
ILE A 405
VAL A 337
TYR A 494
ILE A 397
1.49A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ILE B1086
VAL C1104
THR B1098
ILE B1097
ILE B1096
1.52A15.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 8
PRO C1051
TYR C1029
ILE C 891
VAL C 893
ILE C 702
1.64A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
PRO A1051
TYR A1029
ILE A 891
VAL A 893
ILE A 702
1.64A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
PRO C1051
TYR C1029
ILE C 891
VAL C 893
ILE C 702
1.63A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.63A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.59A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.59A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
TYR A 410
ILE A 397
ILE A 405
VAL A 496
1.02A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.59A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6jyt HELICASE
(SARSr-CoV)		5 / 10
ILE A 545
ILE A 512
VAL A 496
THR A 547
ILE A 575
1.47A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6jyt HELICASE
(SARSr-CoV)		5 / 9
ILE A 545
ILE A 512
VAL A 496
THR A 547
ILE A 575
1.50A21.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6kl2 NUCLEOPROTEIN
(MERS-CoV)		4 / 8
TYR A  44
PRO A  64
THR A 148
ILE A 162
1.50A17.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 510
1.03A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		5 / 8
TYR E 380
PRO E 412
ILE E 410
VAL E 433
THR E 430
1.43A22.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		5 / 9
TYR E 380
PRO E 412
ILE E 410
VAL E 433
THR E 430
1.41A22.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 9
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.35A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 9
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.53A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 330
ILE B 106
1.46A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.53A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.35A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 341
ILE B 106
1.40A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.53A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
TYR A  87
ILE A  86
VAL A  96
ILE A 201
1.40A16.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m71 NSP8
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 130
THR B 141
1.36A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6m71 NSP8
(SARS-CoV-2)		4 / 8
ILE B 185
ILE B 132
VAL B 160
ILE B 172
1.53A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.35A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
TYR A 410
ILE A 397
ILE A 405
VAL A 496
0.94A13.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
PRO B1051
TYR B1029
ILE B 891
VAL B 893
ILE B 702
1.63A13.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
TYR A 410
ILE A 397
ILE A 405
VAL A 496
TYR A 481
1.62A13.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
TYR A 410
ILE A 397
ILE A 405
VAL A 496
TYR A 481
1.63A13.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6nus NSP12
NSP8
(SARSr-CoV)		5 / 9
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.53A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6nus NSP12
NSP8
(SARSr-CoV)		5 / 10
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.53A21.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR B 423
ILE B 410
ILE B 418
VAL B 510
TYR B 495
1.55A13.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.58A13.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
TYR C 170
ILE C 203
ILE C 119
VAL C 227
ILE C 231
1.51A13.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 510
1.02A13.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 510
1.06A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR B 423
ILE B 410
ILE B 418
VAL B 510
0.95A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.52A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.53A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.52A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.50A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.49A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
PRO B1069
TYR B1047
ILE B 909
VAL B 911
ILE B 720
1.49A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 510
1.03A14.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 9
PRO B 344
ILE B 323
ILE B 296
VAL B 321
ILE B 306
1.29A20.16
None
None
None
EDO  B 412 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO B 344
ILE B 323
ILE B 296
VAL B 321
ILE B 306
1.30A20.16
None
None
None
EDO  B 412 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 380
PRO C 412
ILE C 410
VAL C 433
1.42A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR L  32
TYR L  27
ILE L  28
VAL C 382
1.77A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ILE C 410
VAL C 407
THR C 376
ILE C 434
1.25A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
PRO H  52
ILE H  34
ILE H  50
ILE H  69
1.77A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 9
TYR C 423
ILE C 410
ILE C 418
VAL C 510
TYR C 495
1.67A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 423
ILE C 410
ILE C 418
VAL C 510
1.02A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
TYR C 423
ILE C 410
ILE C 418
VAL C 510
TYR C 495
1.66A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR L  32
TYR L  91
ILE H  98
VAL C 382
1.78A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 423
ILE C 410
ILE C 418
VAL C 433
1.41A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 495
TYR C 453
ILE C 418
VAL C 350
1.71A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
TYR C 423
ILE C 410
ILE C 402
VAL C 433
1.24A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
TYR C 423
ILE C 410
ILE C 418
VAL C 510
TYR C 495
1.67A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A7088
VAL A6894
THR A6908
ILE A6910
1.62A22.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6979
ILE A6969
ILE A6967
ILE A7005
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6925
VAL A6916
ILE A6951
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6967
ILE A6951
VAL A6965
ILE A6866
1.78A22.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 8
PRO B4337
TYR B4329
ILE B4334
VAL B4274
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A7009
ILE A6955
VAL A6965
ILE A6866
1.71A22.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
ILE A6967
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
VAL A6916
1.75A22.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.72A18.40
None
None
FMT  A7109 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
ILE A6967
1.20A18.40
FMT  A7109 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A7088
VAL A6894
THR A6908
ILE A6910
1.66A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.73A18.40
None
None
FMT  A7109 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C6950
ILE C6866
ILE C6925
ILE C6967
1.19A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
PRO B4337
TYR B4329
ILE B4334
VAL B4274
1.51A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6925
VAL A6916
ILE A6951
1.31A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6979
ILE A6969
ILE A6967
ILE A7005
1.53A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C7088
VAL C6894
THR C6908
ILE C6910
1.64A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6925
VAL C6916
ILE C6951
1.32A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C6950
ILE C6866
ILE C6925
VAL C6916
1.74A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
VAL A6916
1.72A18.40
FMT  A7109 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE A6967
ILE A6951
VAL A6965
ILE A6866
1.78A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C7009
ILE C6955
VAL C6965
ILE C6866
1.69A18.40
 NA  C7103 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6925
VAL C6894
ILE C6926
1.69A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 8
PRO D4337
TYR D4329
ILE D4334
VAL D4274
1.50A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR C6979
ILE C6969
ILE C6967
ILE C7005
1.53A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 8
TYR A7009
ILE A6955
VAL A6965
ILE A6866
1.70A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR B  27
PRO B  46
ILE B   5
VAL B   7
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 9
TYR C 273
TYR C 264
ILE C 300
VAL C 165
ILE C 276
1.77A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR A  27
PRO A  46
ILE A   5
VAL A   7
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 8
TYR C 273
TYR C 264
ILE C 300
VAL C 165
ILE C 276
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
TYR C  27
PRO C  46
ILE C   5
VAL C   7
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR C6979
ILE C6969
ILE C6967
ILE C7005
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR C6950
ILE C6866
ILE C6925
ILE C6967
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ILE A6926
ILE A6866
TYR A6950
ILE A6951
ILE A6967
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6979
ILE A6969
ILE A6967
ILE A7005
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
ILE A6967
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6925
VAL A6916
ILE A6951
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6925
VAL C6916
ILE C6951
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ILE B 157
VAL A 158
THR B  76
ILE B  74
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR A 111
TYR A  86
ILE A 130
ILE A 131
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR D 111
TYR D  86
ILE D 130
ILE D 131
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR A  87
ILE A 131
ILE A 130
VAL A 133
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR C 111
TYR C  86
ILE C 130
ILE C 131
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR B 111
TYR B  86
ILE B 130
ILE B 131
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
TYR D  87
ILE D 131
ILE D 130
VAL D 133
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6925
VAL A6916
ILE A6951
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP10
(SARS-CoV-2)		4 / 8
PRO D4337
TYR D4329
ILE D4334
VAL D4274
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR A6979
ILE A6969
ILE A6967
ILE A7005
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
ILE A6967
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR C6979
ILE C6969
ILE C6967
ILE C7005
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
TYR C6950
ILE C6866
ILE C6925
ILE C6967
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 8
ILE C6866
ILE C6925
VAL C6916
ILE C6951
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A  97
VAL A  85
THR A  99
ILE A  80
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B  97
VAL B  85
THR B  99
ILE B  80
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO A 344
ILE A 323
ILE A 296
VAL A 321
ILE A 306
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 9
PRO B 344
ILE B 328
ILE B 296
VAL B 321
ILE B 306
1.76A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
TYR B 231
ILE B 307
ILE B 236
VAL B 304
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO B 344
ILE B 323
VAL B 319
ILE B 306
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO A 344
ILE A 323
VAL A 319
ILE A 306
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO A 344
ILE A 323
ILE A 296
VAL A 321
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO A 344
ILE A 323
ILE A 296
VAL A 321
ILE A 306
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
TYR A 231
ILE A 307
ILE A 236
VAL A 304
1.48A
SO4  A 410 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO B 344
ILE B 328
ILE B 296
VAL B 321
ILE B 306
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO A 344
ILE A 328
ILE A 323
ILE A 306
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO B 344
ILE B 328
ILE B 296
VAL B 321
ILE B 306
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
TYR A 194
ILE A 306
VAL A 321
ILE A 296
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO B 344
ILE B 328
ILE B 323
ILE B 306
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO B 344
ILE B 323
ILE B 296
VAL B 321
ILE B 306
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE A  80
VAL A 102
THR A 106
ILE A 108
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
PRO B 344
ILE B 323
ILE B 296
VAL B 321
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO A 344
ILE A 328
ILE A 296
VAL A 321
ILE A 306
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 8
ILE B  80
VAL B 102
THR B 106
ILE B 108
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 9
PRO B 344
ILE B 323
ILE B 296
VAL B 321
ILE B 306
1.40A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 9
PRO A 344
ILE A 323
ILE A 296
VAL A 321
ILE A 306
1.40A20.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PRO B 344
ILE B 323
ILE B 296
VAL B 321
ILE B 306
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ILE A6866
ILE A6925
VAL A6916
ILE A6951
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6950
ILE A6866
ILE A6925
ILE A6967
1.17A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wq3 NSP10
(SARS-CoV-2)		4 / 8
PRO B4337
TYR B4329
ILE B4334
VAL B4274
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
TYR A6979
ILE A6969
ILE A6967
ILE A7005
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wqd NSP8
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 167
ILE B 185
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
TYR A  27
PRO A  46
ILE A   5
VAL A   7
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
TYR D 138
ILE D 132
VAL D 167
ILE D 185
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 167
ILE B 185
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A  71
TYR A  46
ILE A  90
ILE A  91
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A  47
ILE A  91
ILE A  90
VAL A  93
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 380
PRO A 412
ILE A 410
VAL A 433
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 433
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
TYR B  27
PRO L  65
ILE L  81
ILE L  54
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PRO E 384
ILE E 434
THR H  31
ILE H  30
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 433
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.72A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 380
PRO E 412
ILE E 410
VAL E 433
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 510
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.70A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE A 410
VAL A 407
THR A 376
ILE A 434
1.26A
None
DMS  A 903 ( 4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 8
TYR H  27
PRO C  65
ILE C  81
ILE C  54
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 410
VAL E 407
THR E 376
ILE E 434
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 402
VAL E 433
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 402
VAL A 433
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 510
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 380
PRO E 412
ILE E 410
VAL E 433
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 402
VAL E 433
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 433
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 410
VAL E 407
THR E 376
ILE E 434
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 510
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
TYR E 508
ILE H  30
VAL E 407
ILE E 434
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.70A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 402
VAL E 433
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR A 423
ILE A 410
ILE A 418
VAL A 510
TYR A 495
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE A 410
VAL A 407
THR A 376
ILE A 434
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ILE E 410
VAL E 407
THR E 376
ILE E 434
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 380
PRO A 412
ILE A 410
VAL A 433
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PRO E 384
ILE E 434
THR H  31
ILE H  30
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
TYR E 423
ILE E 410
ILE E 418
VAL E 510
TYR E 495
1.70A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 380
PRO E 412
ILE E 410
VAL E 433
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 402
VAL A 433
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 433
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 433
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PRO A 384
ILE A 434
THR B  31
ILE B  30
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR E 423
ILE E 410
ILE E 418
VAL E 510
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
TYR A 423
ILE A 410
ILE A 418
VAL A 510
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 10
ILE A 696
ILE A 757
MET A 755
VAL A 700
TYR A 619
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 10
ILE A 696
ILE A 757
MET A 755
VAL A 700
TYR A 619
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
TYR A  87
ILE A  86
VAL A  96
ILE A 201
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 9
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.40A22.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 330
ILE B 106
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7btf NSP8
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 130
THR B 141
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP8
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 130
THR B 141
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 330
ILE B 106
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 9
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.50A22.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A  87
ILE A  86
VAL A  96
ILE A 201
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 9
PRO B 121
ILE B 119
VAL A 341
ILE B 106
ILE B 107
1.47A22.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
TYR A 867
PRO A 868
ILE A 864
ILE A 837
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PRO B 121
ILE B 119
VAL A 330
ILE B 106
ILE B 107
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP8
(SARS-CoV-2)		4 / 8
PRO D 116
ILE D 106
ILE D 120
ILE D 119
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 341
ILE B 106
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 330
ILE B 106
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
TYR A 867
PRO A 868
ILE A 864
ILE A 837
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 8
PRO B 121
ILE B 119
VAL A 341
ILE B 106
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		7bv2 NSP8
(SARS-CoV-2)		4 / 8
TYR B 138
ILE B 132
VAL B 130
THR B 141
1.21A
None