Ligand ID: X89


Drugbank ID:
DB01110
(Miconazole)


Indication:
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.

Get human targets for X89 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'X89'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.32A21.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE D 916
ALA D1171
LEU E 920
ALA E 926
LEU E 927
1.24A15.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA B 234
VAL B 204
LEU B 250
ALA B 210
TYR B 209
1.34A22.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE I  16
ALA H  23
LEU K  20
ALA K  26
LEU K  27
1.26A8.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		1zvb E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A   1
LEU A   2
VAL A   6
LEU C   2
LEU B   9
1.34A7.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2ajf ACE2
(Homo
sapiens)		5 / 12
ALA B 443
LEU B 440
HIS B 241
ALA B 251
LEU B 248
1.27A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 916
ALA D1172
LEU C 920
ALA C 926
LEU C 927
1.27A6.22
ACE  B 913 ( 3.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2bx3 MAIN PROTEINASE
(SARS-COV
Sin2774)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.32A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		6 / 12
ALA B 160
LEU B 161
VAL B 156
LEU B 141
ALA B  18
LEU B  11
1.71A20.37
None
None
APR  B 477 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 12
LEU A  93
VAL A  75
HIS A  70
ALA A  65
LEU A  66
1.22A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.31A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2liz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.34A15.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.34A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE D 252
LEU D 299
VAL D 303
ALA D 231
LEU D 331
1.28A23.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE A 436
ALA A 443
LEU A 440
ALA A 251
LEU A 248
1.25A20.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.32A21.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ALA C 234
VAL A 204
LEU C 250
ALA A 210
TYR A 209
1.34A14.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ALA B 443
LEU B 440
HIS B 241
ALA B 251
LEU B 248
1.28A19.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
ILE D 332
ALA D 396
LEU D 383
VAL D 317
ALA D 344
1.32A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.34A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.42A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
LEU A 242
LEU A 250
TYR A 209
LEU A 208
1.71A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A 249
LEU A 250
VAL A 261
LEU A 242
ALA A 266
1.78A15.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5x5f S PROTEIN
(MERS-CoV)		6 / 12
ALA B 838
LEU B 835
VAL B 802
LEU B1078
ALA B1037
LEU B1036
1.45A13.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 916
LEU A 920
LEU C 920
ALA C 926
LEU C 927
1.34A11.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6acj ACE2
(Homo
sapiens)		5 / 12
ALA D 443
LEU D 440
HIS D 241
ALA D 251
LEU D 248
1.20A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6cs2 ACE2
(Homo
sapiens)		5 / 12
ALA D 443
LEU D 440
HIS D 241
ALA D 251
LEU D 248
1.32A20.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens;
SARSr-CoV)		6 / 12
ALA A 125
LEU A 126
HIS A   9
LEU A 160
TYR A 159
LEU C   5
1.40A18.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE C 934
ALA C1190
LEU C 938
LEU B 938
LEU B 945
1.47A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE D 934
ALA D1190
LEU D 938
LEU F 938
LEU F 945
1.41A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE A 934
ALA A1190
LEU A 938
LEU C 938
LEU C 945
1.48A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		6 / 12
ILE D 934
ALA D1190
LEU D 938
LEU F 938
ALA F 944
LEU F 945
1.39A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE B 934
ALA B1190
LEU B 938
LEU A 938
LEU A 945
1.44A18.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.45A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.52A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.44A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.51A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m17 ACE2
(Homo
sapiens)		5 / 12
ALA B 443
LEU B 440
HIS B 241
ALA B 251
LEU B 248
1.28A18.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C 234
LEU C 250
ALA C 210
TYR C 209
LEU C 208
1.52A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C 206
LEU C 208
LEU C 271
ALA C 285
LEU C 286
1.57A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA D 206
LEU D 208
LEU D 271
ALA D 285
LEU D 286
1.51A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.59A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA C 234
VAL C 204
LEU C 250
ALA C 210
TYR C 209
1.36A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 206
LEU B 208
LEU B 271
ALA B 285
LEU B 286
1.39A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.45A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.32A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
TYR A 346
ALA A 382
LEU A 329
ALA B 110
LEU A 271
1.51A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 171
TYR A 156
ALA A 176
LEU A 142
LEU A 212
1.68A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  68
ALA C  65
VAL C  16
LEU D  95
LEU C  55
1.56A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m71 NSP7
(SARS-CoV-2)		5 / 12
ALA C  30
LEU C  28
VAL C  22
ALA C  65
LEU C  59
1.61A10.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
PHE A  45
TYR A 129
ALA A 706
LEU A 708
LEU A 240
1.67A17.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
VAL A 147
HIS A 138
ALA A 124
LEU A 127
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
VAL A 147
LEU A 140
ALA A 124
LEU A 127
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE B 168
VAL B 147
HIS B 138
ALA B 124
LEU B 127
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
ALA B  50
LEU B  53
VAL B  24
LEU B 123
ALA B  21
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
PHE H 122
ALA H 125
LEU H 124
VAL L 133
LEU L 181
1.57A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6951
PHE A6954
ALA A6966
ALA A6905
LEU A6893
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 12
PHE B4321
VAL A6882
HIS B4301
ALA A6843
LEU A7042
1.74A16.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 160
VAL B 155
HIS B 138
ALA B  38
LEU B 127
1.78A18.09
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 160
VAL A 155
HIS A 138
ALA A  38
LEU A 127
1.70A18.09
None
AMP  A 201 ( 4.4A)
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
VAL A 155
LEU A 140
ALA A 129
LEU A 127
1.73A18.09
None
AMP  A 201 ( 4.4A)
None
AMP  A 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ILE B  18
PHE B 168
LEU B 153
ALA B 134
LEU B 109
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B 168
VAL B 147
HIS B 138
ALA B 124
LEU B 127
1.78A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.56A
None
None
AMP  A 201 ( 3.4A)
AMP  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B 168
VAL B 155
LEU B 140
ALA B 129
LEU B 127
1.74A18.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE C6951
PHE C6954
ALA C6966
ALA C6905
LEU C6893
1.49A18.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
PHE B4321
VAL A6882
HIS B4301
ALA A6843
LEU A7042
1.76A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 12
PHE D4321
VAL C6882
HIS D4301
ALA C6843
LEU C7042
1.75A17.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
ALA B 153
LEU B 152
ALA B 114
TYR B  95
LEU B 117
1.69A
None
None
CL  B 502 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ALA A 107
LEU A 106
VAL A 102
LEU A  45
TYR A  89
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
VAL A 147
LEU A 140
ALA A 124
LEU A 127
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
PHE A 168
VAL A 147
HIS A 138
ALA A 124
LEU A 127
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
PHE A 320
TYR A 317
ALA A 333
VAL A 253
ALA A 231
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wiq NSP7
(SARS-CoV-2)		5 / 12
ALA A  30
LEU A  28
VAL A  22
ALA A  65
LEU A  59
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  68
ALA A  65
VAL A  16
LEU B  95
LEU A  55
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE C6951
PHE C6954
ALA C6966
ALA C6905
LEU C6893
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE C6951
PHE C6954
ALA C6966
ALA C6905
LEU C6893
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
LEU A 250
ALA A 210
TYR A 209
LEU A 208
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.62A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE D 116
TYR D 113
ALA D 129
VAL D  49
ALA D  27
1.63A
None
None
APR  D 201 (-3.7A)
APR  D 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE C 116
TYR C 113
ALA C 129
VAL C  49
ALA C  27
1.62A
None
None
APR  C 201 (-3.7A)
APR  C 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.61A
None
None
APR  A 201 (-3.7A)
APR  A 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6951
PHE A6954
ALA A6966
ALA A6905
LEU A6893
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wqd NSP7
(SARS-CoV-2)		5 / 12
ALA A  30
LEU A  28
VAL A  22
ALA A  65
LEU A  59
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wqd NSP7
(SARS-CoV-2)		5 / 12
ALA C  30
LEU C  28
VAL C  22
ALA C  65
LEU C  59
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6wxd NSP9
(SARS-CoV-2)		5 / 12
ALA B 108
LEU B 106
VAL B 102
LEU A   4
LEU A  97
1.37A15.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA B 206
LEU B 208
LEU B 271
ALA B 285
LEU B 286
1.30A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ILE A 249
LEU A 250
VAL A 261
LEU A 242
ALA A 266
1.78A15.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.34A15.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
LEU A 242
LEU A 250
TYR A 209
LEU A 208
1.71A15.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 219
LEU A 282
LEU A 208
TYR A 209
LEU A 253
1.76A15.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU A  55
VAL A  58
LEU B  91
ALA A  65
LEU A  20
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA A  30
LEU A  28
VAL A  22
ALA A  65
LEU A  59
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE B 107
ALA B 110
VAL A  66
LEU B  91
LEU A  20
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA C  30
LEU C  28
VAL C  22
ALA C  65
LEU C  59
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.35A
None
None
None
None
PEG  A 404 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C 116
TYR C 113
ALA C 129
VAL C  49
ALA C  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE E 116
TYR E 113
ALA E 129
VAL E  49
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  23
ALA A 124
LEU A 123
HIS A  94
LEU A  88
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE D 116
TYR D 113
ALA D 129
VAL D  49
ALA D  27
1.50A
None
None
EDO  D 205 (-4.5A)
EDO  D 209 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE D 116
TYR D 113
ALA D 129
VAL D  49
ALA D  27
1.60A
None
None
APR  D 201 (-3.4A)
APR  D 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.59A
None
None
APR  A 201 ( 3.7A)
APR  A 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C 116
TYR C 113
ALA C 129
VAL C  49
ALA C  27
1.59A
None
None
APR  C 201 (-3.6A)
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE E 116
TYR E 113
ALA E 129
VAL E  49
ALA E  27
1.59A
None
None
APR  E 201 (-3.5A)
APR  E 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.58A
None
None
APR  B 201 (-3.6A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A 116
TYR A 113
ALA A 129
VAL A  49
ALA A  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C 116
TYR C 113
ALA C 129
VAL C  49
ALA C  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE B  18
PHE B 168
LEU B 153
ALA B 134
LEU B 109
1.68A
None
None
None
EDO  B 204 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ILE A  18
PHE A 168
LEU A 153
ALA A 134
LEU A 109
1.63A
None
None
None
EDO  A 205 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B 116
TYR B 113
ALA B 129
VAL B  49
ALA B  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 528
ALA A 685
VAL A 662
ALA A 656
LEU A 655
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A  45
TYR A 129
ALA A 706
LEU A 708
LEU A 240
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
TYR A 346
ALA A 382
LEU A 329
ALA B 110
LEU A 271
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE D 107
ALA D 110
VAL C  66
LEU D  91
LEU C  20
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 632
ALA A 656
VAL A 662
HIS A 642
ALA A 685
1.62A
None
None
None
ZN  A1002 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 171
TYR A 156
ALA A 176
LEU A 142
LEU A 212
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP7
(SARS-CoV-2)		5 / 12
ALA C  30
LEU C  28
VAL C  22
ALA C  65
LEU C  59
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 685
VAL A 662
HIS A 642
ALA A 656
LEU A 655
1.55A
None
None
ZN  A1002 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
LEU C  55
VAL C  58
LEU D  91
ALA C  65
LEU C  20
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
VAL A 204
LEU A 250
ALA A 210
TYR A 209
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 206
LEU A 208
LEU A 271
ALA A 285
LEU A 286
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
PHE A  45
TYR A 129
ALA A 706
LEU A 708
LEU A 240
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 632
ALA A 656
VAL A 662
HIS A 642
ALA A 685
1.63A
None
None
None
ZN  A1002 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 171
TYR A 156
ALA A 176
LEU A 142
LEU A 212
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
LEU A 212
LEU A 178
ALA A 250
LEU A 245
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
TYR A 346
ALA A 382
LEU A 329
ALA B 110
LEU A 271
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 685
VAL A 662
HIS A 642
ALA A 656
LEU A 655
1.58A
None
None
ZN  A1002 (-3.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
PHE A 528
ALA A 685
VAL A 662
ALA A 656
LEU A 655
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 171
TYR A 156
ALA A 176
LEU A 142
LEU A 212
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 685
VAL A 662
HIS A 642
ALA A 656
LEU A 655
1.63A
 A  T  11 ( 4.7A)
None
ZN  A1002 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 348
TYR A 346
LEU A 663
LEU A 351
LEU A 636
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
TYR A 346
ALA A 382
LEU A 329
ALA B 110
LEU A 271
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A  45
TYR A 129
ALA A 706
LEU A 708
LEU A 240
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
LEU A 212
LEU A 178
ALA A 250
LEU A 245
1.68A
None