Ligand ID: DHI


Drugbank ID:
DB00117
(L-Histidine)


Indication:
The actions of supplemental L-histidine are entirely unclear. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol.

Get human targets for DHI in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'DHI'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
SER B 144
GLY B 120
GLY B  29
0.96A12.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 4
SER A   0
GLY B 170
GLY A   2
GLY B 138
1.28A11.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		1x7q HLA, A-11
(Homo
sapiens)		4 / 4
GLY A 100
TYR A 113
GLY A 112
ASP A 102
1.23A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		1x7q HLA, A-11
(Homo
sapiens)		3 / 3
TYR A 209
GLY A 207
PHE A 241
1.18A10.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		1x7q HLA, A-11
(Homo
sapiens)		4 / 6
PHE A 208
PRO A 184
LYS A 186
THR A 187
1.78A10.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		1x7q BETA-2-MICROGLOBULIN
HLA, A-11
(Homo
sapiens)		3 / 3
TYR B  63
PRO A 235
LEU B  65
1.54A5.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
TYR B1209
PRO B1293
LEU B1202
1.48A2.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PRO A 122
GLY A  15
GLY A  11
GLY B1011
0.87A12.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 6
GLY D   4
PRO D   2
LYS E 102
THR E  98
1.61A13.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2ajf ACE2
(Homo
sapiens)		3 / 3
SER A 409
GLY A 405
GLY A 377
1.01A9.11
9.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY F 434
TYR F 436
GLY F 482
ASP B  38
1.30A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
GLY A 352
GLY A 354
GLY E 488
GLY E 490
0.94A9.11
9.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY A 354
TYR E 491
GLY E 490
ASP E 392
1.45A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2ajf ACE2
SPIKE PROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 6
GLY E 490
GLY E 488
GLY A 354
GLY A 352
0.89A19.73
20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY A  11
0.91A11.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 6
ARG E 294
PRO E 365
LYS E 362
THR E 363
1.54A11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		3 / 3
TYR G 334
GLY G 336
PHE G 315
1.35A11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		3 / 3
SER H  35
GLY H 100
GLY S 488
1.03A16.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L  46
TRP H 103
GLY H 104
1.45A10.33
5.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		2dd8 IGG HEAVY CHAIN
IGG LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY S 490
TYR L  96
GLY H  99
ASP H  95
1.70A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 159
TRP H 154
GLY H 139
1.37A10.50
6.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		2fyg REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 6
ASN A  62
GLN A  65
THR A  56
PRO A  59
1.64A19.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
ARG U 113
GLY U 109
PRO U  37
THR U  39
1.76A11.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		3 / 3
SER F  67
GLY F  52
GLY F  50
1.04A22.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
ASN H  62
GLN H  65
THR H  56
PRO H  59
1.41A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 4
GLY A  87
TYR A  57
GLY A  83
ASP A  82
1.31A12.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
GLY C 488
TYR C 491
GLY C 490
ASP C 392
1.78A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
TYR E 367
GLY E 400
PHE E 416
1.62A13.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2ghw ANTI-SCFV ANTIBODY,
80R
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
SER D 101
GLY C 482
GLY C 488
GLY C 391
1.41A17.48
None
None
CL  C  20 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 6
ARG A 278
GLY A 288
LYS A 362
THR A 363
1.63A11.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		3 / 3
SER A 287
GLY A 246
GLY A 238
0.93A11.88
12.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		3 / 3
TYR A 237
GLY A 238
PHE A 232
1.41A6.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2idy NSP3
(SARSr-CoV)		3 / 3
TYR A 104
GLY A  95
PHE A  26
1.61A15.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 4
SER A 319
GLY A 336
GLY A 317
GLY B 285
1.56A20.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		4 / 6
GLY A  77
PRO A 100
LYS A  99
THR A 102
1.22A15.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2og3 NUCLEOCAPSID PROTEIN
(SARS-COV
Tor2)		3 / 3
TYR A 113
GLY A 117
PHE A 111
1.71A14.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
LEU C 331
TRP C 332
GLY B  37
1.35A9.54
3.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 6
PRO B 122
GLY B  11
GLY B  15
GLY A  11
0.95A12.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
TYR B 237
GLY B 247
PHE B 232
1.09A6.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
GLY A 246
GLY A 247
GLY A 238
GLY A 253
0.97A11.61
11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		3 / 3
SER F 287
GLY F 246
GLY F 238
0.96A11.61
11.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2w2g NSP3
(SARSr-CoV)		3 / 3
SER B 461
GLY B 494
GLY A 465
0.95A13.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		2w2g NSP3
(SARSr-CoV)		3 / 3
TYR B 487
PRO B 515
LEU B 514
1.13A3.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2wct NSP3
(SARSr-CoV)		4 / 4
SER C 461
GLY C 466
GLY C 494
GLY B 465
1.36A13.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 4
SER A 166
GLY A 208
GLY A 164
GLY A 278
1.29A15.32
 NA  A1295 (-2.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
PRO A  62
GLY A 278
GLY A 164
GLY A 165
0.91A15.32
None
None
None
NA  A1295 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		3 / 3
SER A 166
GLY A 164
GLY A 278
0.85A15.32
 NA  A1295 (-2.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		3 / 3
SER A 166
GLY A 164
GLY A 278
0.84A15.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		2xyr NSP10
(SARSr-CoV)		4 / 6
ASN B  62
GLN B  65
THR B  56
PRO B  59
1.66A16.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		2xyv NSP10
(SARSr-CoV)		4 / 6
ASN B  62
GLN B  65
THR B  56
PRO B  59
1.69A16.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
PRO A  62
GLY A 278
GLY A 164
GLY A 165
0.91A15.32
None
None
None
NA  A1294 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 4
SER A 166
GLY A 208
GLY A 164
GLY A 278
1.28A15.32
 NA  A1294 (-2.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		4 / 4
GLY A 488
TYR A 491
GLY A 490
ASP A 392
1.80A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		3bgf F26G19 FAB
(Mus
musculus)		3 / 3
TYR H 177
GLY H 146
PHE H 148
0.77A9.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
SARSr-CoV)		4 / 6
ARG C  66
GLY C  68
PRO S 466
LYS S 465
1.76A9.00
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		3bgf F26G19 FAB
(Mus
musculus)		3 / 3
PHE L 209
TYR L 186
PRO L 119
1.50A42.27
0.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY F 490
GLY F 488
GLY B 354
GLY B 352
0.94A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 5
TYR A  34
GLU A  30
TYR E 408
PRO E 477
1.78A16.61
0.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY E 490
GLY E 488
GLY A 354
GLY A 352
0.87A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
TYR B 454
PRO B 451
LEU B 450
0.94A1.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY A 352
GLY A 354
GLY E 488
GLY E 490
0.91A9.11
9.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
GLY F 488
TYR F 491
GLY F 490
ASP F 392
1.77A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
SER E 487
GLY A 354
GLY E 490
0.99A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY F 490
GLY F 488
GLY B 354
GLY B 352
0.87A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
SER E 487
GLY A 354
GLY E 490
1.00A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3d0i SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 4
GLY E 488
TYR E 491
GLY E 490
ASP E 392
1.75A17.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3d0i ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 4
GLY A 354
TYR E 491
GLY E 490
ASP E 392
1.43A21.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY A  11
0.90A14.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 4
SER A 139
GLY A 143
GLY B   2
GLY A 170
1.50A13.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		3i6g BETA-2-MICROGLOBULIN
HLA, A-2
(Homo
sapiens)		3 / 3
PHE A 241
TYR B  63
PRO A 235
1.34A25.35
12.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3i6k HLA, A-2
(Homo
sapiens)		4 / 4
GLY A 100
TYR A 113
GLY A 112
ASP A 102
1.18A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		3i6l HLA, A-24
(Homo
sapiens)		3 / 3
TYR D 209
GLY D 207
PHE D 241
1.19A9.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3i6l HLA, A-24
(Homo
sapiens)		4 / 4
GLY D 100
TYR D 113
GLY D 112
ASP D 102
1.28A20.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		3i6l HLA, A-24
(Homo
sapiens)		4 / 6
PHE D 208
PRO D 184
LYS D 186
THR D 187
1.67A9.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		3 / 3
TYR A 209
PRO C 293
LEU A 202
1.51A2.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY A  11
0.94A12.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
PRO B 122
GLY B  11
GLY B  15
GLY A  11
0.97A11.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		3r24 NSP10 AND NSP11
(SARSr-CoV)		4 / 6
ASN B  62
GLN B  65
THR B  56
PRO B  59
1.66A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		3 / 3
SER A 166
GLY A 164
GLY A 278
0.89A13.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
PRO A  62
GLY A 278
GLY A 164
GLY A 165
0.86A13.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 4
SER A 166
GLY A 208
GLY A 164
GLY A 278
1.33A13.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3sci ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY E 434
TYR E 436
GLY E 482
ASP A  38
1.27A19.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		3sci ACE2
(Homo
sapiens)		3 / 3
TYR A 454
PRO A 451
LEU A 450
0.87A1.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3scj ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY F 434
TYR F 436
GLY F 482
ASP B  38
1.58A17.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3scj ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY A 354
TYR E 491
GLY E 490
ASP E 392
1.48A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY E 490
GLY E 488
GLY A 354
GLY A 352
0.96A19.46
20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 4
GLY A 354
TYR E 491
GLY E 490
ASP E 392
1.50A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY E 490
GLY E 488
GLY A 354
GLY A 352
0.96A19.18
19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
GLY A 352
GLY A 354
GLY E 488
GLY E 490
0.96A9.11
9.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		3 / 3
TYR B 454
PRO B 451
LEU B 450
0.87A1.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		3scl ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 5
TYR B  34
GLU B  30
TYR F 408
PRO F 477
1.78A16.61
0.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		3to2 MHC CLASS I ANTIGEN
(Homo
sapiens)		4 / 6
PHE A 208
PRO A 185
LYS A 186
THR A 187
1.76A10.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 6
PRO A 249
GLY A 164
GLY B  75
GLY A 272
GLY A 267
1.77A13.25
12.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		4 / 6
ARG A 229
GLY A 228
PRO A 224
THR B  66
1.76A7.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
SER B  56
GLY B  59
GLY B   6
0.85A9.94
10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		3 / 3
SER A  11
GLY B   6
GLY B  59
0.88A18.37
19.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		5c8t NSP10
(SARSr-CoV)		4 / 6
ARG A 113
PHE A 110
PRO A 107
THR A 101
1.73A12.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		5c8u NSP10
(SARSr-CoV)		4 / 6
ASN A  62
GLN A  65
THR A  56
PRO A  59
1.39A18.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		3 / 3
SER B  56
GLY B   6
GLY B  59
0.79A9.94
10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		3 / 3
TYR B  64
GLY A  35
PHE A  16
1.58A6.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5e6j REPLICASE
POLYPROTEIN 1AB
UBIQUITIN
(SARSr-CoV;
synthetic
construct)		5 / 6
PRO D 249
GLY D 164
GLY E  75
GLY D 272
GLY D 267
1.75A13.56
12.93
None
None
AYE  E  76 (-2.4A)
AYE  E  76 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 5
TYR N  30
ASN B  67
TYR B  69
PHE N  16
1.77A14.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
SER M  11
GLY A   6
GLY A  59
0.91A22.50
18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 6
ASN O  62
GLN O  65
THR O  56
PRO O  59
1.48A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
SER C  56
GLY C  59
GLY C   6
0.91A9.94
10.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.75A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.37A19.87
None
None
None
DMS  A 403 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A  39
GLY A  29
GLY A 120
GLY A 143
1.45A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.45A19.87
None
None
None
DMS  A 403 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		3 / 3
TYR B  84
GLY B  39
PHE B  80
1.50A7.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
TYR C 442
ASN C 457
TYR C 338
ARG C 441
1.41A17.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
TYR B 738
GLY A 981
PHE A 952
1.03A3.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		5x4r S PROTEIN
(MERS-CoV)		4 / 5
TYR A 293
PHE A 204
TYR A  85
PRO A 297
1.60A23.89
0.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		5x59 S PROTEIN
(MERS-CoV)		3 / 3
TYR B 184
PRO B 285
LEU B 284
1.58A0.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		5x59 S PROTEIN
(MERS-CoV)		3 / 3
TYR B  64
GLY A 624
PHE B 327
1.25A2.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ASN A 901
GLN A 904
THR A 698
PRO A 697
1.44A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		3 / 3
TYR B 438
GLY B 434
PHE B 483
1.25A4.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
ARG C 453
GLY A 225
PRO A 223
LYS A 221
1.45A4.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ASN A 521
GLN B 261
THR A 477
PRO A 476
1.66A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
PRO C1167
GLY A 963
GLY C 984
GLY C 982
0.73A4.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5x5f S PROTEIN
(MERS-CoV)		3 / 3
SER B 439
GLY B 578
GLY C  61
0.81A4.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		5x5f S PROTEIN
(MERS-CoV)		4 / 5
TYR A 293
PHE A 204
TYR A  85
PRO A 297
1.58A11.37
0.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5x5f S PROTEIN
(MERS-CoV)		4 / 4
SER B 439
GLY B 610
GLY B 578
GLY C  61
1.35A4.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		5x5f S PROTEIN
(MERS-CoV)		4 / 4
GLY A1120
TYR A1141
GLY A 984
ASP A1182
1.66A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN B 901
GLN B 904
THR B 698
PRO B 697
1.35A12.14
ASN  B 901 ( 0.6A)
GLN  B 904 ( 0.6A)
THR  B 698 ( 0.8A)
PRO  B 697 ( 1.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
SER B  36
GLY B 212
GLY B  39
0.75A5.66
5.47
SER  B  36 ( 0.0A)
GLY  B 212 ( 0.0A)
GLY  B  39 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 5
TYR C 442
ASN C 457
TYR C 338
ARG C 441
1.52A17.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
SER C 623
GLY C 625
GLY C 638
0.82A5.66
5.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6acg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY C 434
TYR C 436
GLY C 482
ASP D  38
1.47A16.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
TYR C 491
GLY C 488
PHE C 483
1.35A3.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
PHE A 483
TYR A 494
PRO A 493
1.54A11.14
50.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ASN A 304
GLN A 301
THR C 841
PRO C 844
1.54A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6ack ACE2
(Homo
sapiens)		3 / 3
LEU D 444
TRP D 275
GLY D 272
1.49A10.23
2.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
TYR B 195
PRO B 223
LEU B 222
1.03A1.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ARG C 887
GLY C1017
LYS C1010
THR C1009
1.57A3.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
PHE A 193
TYR C 383
PRO A 223
1.47A11.89
25.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
TYR A1049
GLY A 892
PHE A 888
1.69A4.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
PHE B 529
PRO B 317
LYS B 566
THR B 567
1.28A4.95
None
None
None
NAG  B1318 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
TYR A  41
PHE C 548
TYR A 195
PRO A 218
1.80A11.89
6.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ASN A 901
GLN A 904
THR A 698
PRO A 697
1.36A12.16
None
NAG  A1310 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H3D_A_DHIA601_0
(DUF2338
DOMAIN-CONTAINING
PROTEIN)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 5
TYR A 442
ASN A 457
TYR A 338
ARG A 441
1.73A17.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
TYR A 195
PRO A 223
LEU A 222
1.02A1.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6cs2 ACE2
(Homo
sapiens)		3 / 3
TYR D 454
PRO D 451
LEU D 450
1.08A1.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6cs2 ACE2
SPIKE
GLYCOPROTEIN,FIBRITI
N
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY B 434
TYR B 436
GLY B 482
ASP D  38
1.56A15.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6cs2 ACE2
SPIKE
GLYCOPROTEIN,FIBRITI
N
(Homo
sapiens;
SARSr-CoV)		4 / 4
GLY D 354
TYR B 491
GLY B 490
ASP B 392
1.64A20.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6cs2 ACE2
(Homo
sapiens)		3 / 3
LEU D 278
TRP D 275
GLY D 448
1.46A10.23
2.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
SER C 703
GLY C1028
GLY C1026
0.77A5.33
5.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6iex BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Homo
sapiens)		3 / 3
TYR B  63
PRO A 235
LEU B  65
1.49A10.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6iex BETA-2-MICROGLOBULIN
MHC CLASS I ANTIGEN
(Homo
sapiens)		3 / 3
PHE A 241
TYR B  63
PRO A 235
1.35A24.49
1.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		4 / 6
PHE A 208
PRO A 184
LYS A 186
THR A 187
1.53A9.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		3 / 3
TYR A 209
GLY A 207
PHE A 241
1.16A9.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6jyt HELICASE
(SARSr-CoV)		3 / 3
TYR A 398
GLY A 400
PHE A 373
1.09A6.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6jyt HELICASE
(SARSr-CoV)		3 / 3
TYR B 541
PRO B 529
LEU B 528
1.53A1.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6jyt HELICASE
(SARSr-CoV)		4 / 6
ARG A  22
GLY A  17
PRO A  47
THR A  58
1.32A6.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6jyt HELICASE
(SARSr-CoV)		3 / 3
SER A 289
GLY A 285
GLY A 538
0.81A8.63
8.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.76A12.21

None
None
ELL  D   3 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A12.21

None
ELL  D   3 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6lzg ACE2
(Homo
sapiens)		3 / 3
TYR A 454
PRO A 451
LEU A 450
0.95A1.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY E 447
TYR E 449
GLY E 496
ASP A  38
1.37A22.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 504
GLY E 502
GLY A 354
GLY A 352
0.99A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A12.50

None
ELL  D   3 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.77A12.50

None
None
ELL  D   3 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 6
GLY E 496
PHE E 497
PRO E 499
LYS E 444
1.62A9.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6m17 ACE2
(Homo
sapiens)		3 / 3
TYR B 454
PRO B 451
LEU B 450
0.94A1.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6m17 ACE2
(Homo
sapiens)		3 / 3
LEU B 148
TRP B 168
GLY B 173
1.14A9.76
2.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 4
SER C 288
GLY C  99
GLY C 285
GLY C 438
1.05A7.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY E 504
GLY E 502
GLY B 354
GLY B 352
0.99A21.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY D 354
TYR F 505
GLY F 504
ASP F 405
1.55A18.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.64A21.51
0.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY F 447
TYR F 449
GLY F 496
ASP D  38
1.30A21.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
TYR A 139
PRO A 149
LEU A 148
1.53A1.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m18 ACE2
(Homo
sapiens)		3 / 3
SER B 547
GLY B 551
GLY B 319
1.06A8.14
8.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
PRO C  73
GLY C  68
GLY C  67
GLY C  66
0.97A7.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
TYR C 292
GLY C  93
PHE C 289
1.19A4.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		3 / 3
SER A 100
GLY A 285
GLY A 438
0.56A7.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  11
GLY C  15
GLY A  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY C  11
GLY A  11
GLY A  15
1.15A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY D  11
0.61A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  11
GLY B  15
GLY D  11
1.03A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY A  11
GLY C  11
GLY C  15
1.29A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER D 147
GLY D 146
GLY D 143
GLY D 120
1.75A12.50

None
None
3WL  D 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY B  15
GLY B  11
GLY D  11
0.84A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  11
GLY C  15
GLY A  11
1.21A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY B  11
GLY D  11
GLY D  15
1.10A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY C  11
GLY A  11
GLY A  15
1.25A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
HIS C 246
GLN C 107
THR C 243
PRO C 241
1.79A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER B 147
GLY B 146
GLY B 143
GLY B 120
1.80A12.50

None
None
3WL  B 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY A  11
GLY C  11
GLY C  15
1.05A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  11
GLY D  15
GLY B  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  11
GLY A  15
GLY C  11
1.06A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO C 122
GLY C  15
GLY C  11
GLY A  11
0.71A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
HIS D 246
GLN D 107
THR D 243
PRO D 241
1.71A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  15
GLY D  11
GLY B  11
0.77A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY D  11
GLY B  11
GLY B  15
1.19A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER C 147
GLY C 146
GLY C 143
GLY C 120
1.77A12.50

None
None
3WL  C 401 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D 143
GLY D 146
GLY D  29
1.23A12.50

None
3WL  D 401 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  15
GLY A  11
GLY C  11
0.82A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  15
GLY A  11
GLY C  11
0.59A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO D 122
GLY D  11
GLY D  15
GLY B  11
1.20A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
PRO B 122
GLY D  11
GLY B  11
GLY B  15
1.26A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.80A12.50

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR A 113
GLY A 117
PHE A 111
1.68A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
0.98A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.25A7.12

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.53A1.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.13A7.12

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.88A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
PHE B 529
PRO B 565
LYS B 566
THR B 567
1.77A4.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
TYR C 738
GLY C 739
PHE A 952
1.64A4.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 173
TRP H 168
GLY H 153
1.34A9.57
6.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6nur NSP12
(SARSr-CoV)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.92A3.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6nus NSP12
(SARSr-CoV)		3 / 3
LEU A 786
TRP A 617
GLY A 616
1.69A3.92
1.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6nus NSP12
(SARSr-CoV)		3 / 3
TYR A 619
PRO A 627
LEU A 630
1.34A1.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER C 884
GLY C 885
GLY C 891
GLY C 889
1.54A5.04
5.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN A 317
GLN A 314
THR B 859
PRO B 862
1.55A11.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR A 266
PRO A 217
LEU A 189
1.55A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6vw1 ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 4
GLY F 447
TYR F 449
GLY F 496
ASP B  38
1.36A19.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6vw1 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
GLY F 496
PHE F 497
PRO F 499
THR F 444
1.47A9.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vw1 ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
GLY F 504
GLY F 502
GLY B 354
GLY B 352
0.98A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6vw1 ANGIOTENSIN-CONVERTI
NG ENZYME 2
SARS-COV-2 CHIMERIC
RBD
(SARSr;
homo
sapiens)		4 / 4
GLY E 447
TYR E 449
GLY E 496
ASP A  38
1.38A19.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
0.93A16.96
17.54
None
SO4  A 201 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
SER B 111
GLY B  79
GLY B  97
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxs NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR C 266
PRO C 217
LEU C 189
1.37A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 380
GLY B 413
PHE B 429
1.66A2.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER A 884
GLY A 885
GLY A 891
GLY A 889
1.50A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ASN C 317
GLN C 314
THR A 859
PRO A 862
1.80A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 721
GLY A1046
GLY A1044
0.98A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 612
GLY B 594
PHE B 318
1.41A2.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
TYR B 266
PRO B 217
LEU B 189
1.40A0.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
SER A 884
GLY A 885
GLY A 891
GLY A 889
1.53A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER B 721
GLY B1046
GLY B1044
0.88A4.56
4.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 239
PHE B 233
1.42A5.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER A 288
GLY A 247
GLY A 239
0.93A11.32
None
CIT  A 412 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  28
GLY H  26
GLY H  24
1.12A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 412
GLY H  97
GLY C 431
GLY C 381
1.72A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY C 381
GLY H  97
GLY C 431
1.62A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  95
GLY H  94
GLY H  35
0.99A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
PRO L  44
GLY L  99
GLY L 101
GLY H  44
1.53A15.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY H  97
GLY C 381
GLY C 431
1.23A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 412
GLY H  97
GLY C 381
GLY C 431
1.51A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  35
GLY H  94
GLY H  95
1.31A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
PRO L  44
GLY L  41
GLY H 106
GLY H 104
1.67A15.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  97
GLY H  95
GLY H  94
1.65A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  94
GLY H  95
GLY H  97
1.60A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY H  95
GLY H  97
GLY C 381
1.45A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  95
GLY H  94
GLY H  35
1.14A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
PRO C 507
GLY C 404
GLY C 504
GLY C 502
1.68A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  95
GLY H  94
GLY H  24
1.58A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 4
GLY H  97
TYR H  32
GLY H  94
ASP H 101
1.30A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		3 / 3
LEU H 159
TRP H 154
GLY H 139
1.28A14.50
6.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  49
GLY H  35
GLY H  94
1.57A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 4
GLY H  97
TYR H  32
GLY H  95
ASP H 101
1.52A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
SER C 494
GLY C 496
GLY C 447
1.27A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
PRO L  44
GLY H  94
GLY H 104
GLY H 106
1.39A15.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		3 / 3
LEU H 159
TRP H 154
GLY H 139
1.34A14.50
6.08
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
PHE L 209
TYR L 186
PRO L 119
1.54A43.23
11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  35
GLY H  94
GLY H  95
1.28A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  97
GLY H  95
GLY H  94
1.70A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  94
GLY H  95
GLY H  97
1.63A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
PRO C 499
GLY C 446
GLY C 447
GLY C 496
1.39A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO C 384
GLY C 381
GLY H  97
GLY C 431
1.59A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		3 / 3
SER C 443
GLY C 447
GLY C 496
1.21A16.25
16.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
PRO H  52
GLY H  94
GLY H  35
GLY H  95
1.23A18.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.86A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w4h NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.40A12.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w4h NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.67A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4378
GLY B4380
GLY B4305
1.57A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.73A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.98A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w61 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.38A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.38A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6875
GLY A6871
GLY A6869
1.80A15.03
SAM  A7104 (-3.9A)
None
SAM  A7104 (-4.4A)
SAM  A7104 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4323
GLY B4347
GLY B4322
1.74A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.62A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4305
GLY B4380
GLY B4378
1.28A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.68A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.34A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.49A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.80A15.03
SAM  A7104 (-3.9A)
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.60A15.03
SAM  A7104 (-3.9A)
SAM  A7104 (-3.6A)
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.29A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.28A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.87A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.14A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w61 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.43A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  51
GLY A  47
GLY A  48
1.35A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.39A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.41A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  51
GLY B  46
1.77A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.22A18.12
18.75
AMP  A 201 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.36A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  48
GLY A  51
GLY A  46
1.78A18.12
18.75
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6w6y NSP3
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.74A18.12
18.75
None
None
None
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  51
GLY B  47
GLY B  48
1.33A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.43A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  47
GLY A  51
GLY A  48
1.47A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.53A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.58A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.20A18.12
18.75
AMP  A 201 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.20A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  48
GLY B  51
1.67A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  47
GLY B  51
GLY B  48
1.50A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO A 125
GLY A  51
GLY A  48
GLY A 130
1.46A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
AMP  A 201 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.34A18.12
18.75
None
None
AMP  A 201 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  48
GLY A  51
GLY A  46
1.71A18.12
18.75
None
AMP  A 201 ( 3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
0.98A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
PRO B 125
GLY B  51
GLY B  48
GLY B 130
1.41A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  48
GLY B  47
GLY B 130
1.38A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.26A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.27A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  51
GLY B  46
1.72A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  48
GLY B  51
1.68A18.12
18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.16A18.12
18.75
None
None
None
AMP  A 201 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w6y NSP3
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  48
GLY B  47
GLY B 130
1.46A18.12
18.75
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C6962
GLY C7076
1.51A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6878
GLY C6869
GLY C6871
GLY C6875
1.64A14.55
SAM  C7105 ( 3.9A)
SAM  C7105 ( 3.8A)
SAM  C7105 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.36A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4347
GLY D4323
GLY D4322
1.28A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.68A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.69A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4378
GLY B4380
GLY B4305
1.59A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4353
GLY D4378
GLY D4380
GLY D4305
1.54A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4353
GLY B4305
GLY B4380
GLY B4378
1.33A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C7076
GLY C6962
1.69A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.85A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4322
GLY D4323
GLY D4347
1.71A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4347
GLY D4323
GLY D4322
1.35A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6962
GLY C7076
GLY C6963
1.33A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.97A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C7076
GLY C6962
1.63A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6878
GLY A6869
GLY A6871
GLY A6875
1.64A14.55
SAM  A7102 ( 3.8A)
SAM  A7102 ( 3.8A)
SAM  A7102 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C6963
GLY C6962
GLY C7076
1.40A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4347
GLY B4323
GLY B4322
1.29A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.72A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A7076
GLY A6962
1.62A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4323
GLY D4347
GLY D4322
1.73A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4312
GLY D4322
GLY D4323
GLY D4347
1.42A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO D4353
GLY D4305
GLY D4380
GLY D4378
1.29A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.12A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4323
GLY B4347
GLY B4322
1.74A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.37A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.48A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6w75 NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.68A18.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP10
(SARS-CoV-2)		4 / 6
PRO B4312
GLY B4322
GLY B4323
GLY B4347
1.43A17.93
18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6963
GLY A6962
GLY A7076
1.38A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6w75 NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.16A14.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
TYR C  71
PRO C 129
LEU C 132
1.73A7.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
MES  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wcf NSP3
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 202 (-3.4A)
MES  A 202 (-4.7A)
MES  A 202 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wen NSP3
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 250
GLY A 251
GLY A 255
GLY A 252
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 252
GLY A 251
GLY A 250
GLY A 255
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		3 / 3
SER A 315
GLY A 283
GLY A 301
0.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 252
GLY A 251
GLY A 250
GLY A 255
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 4
SER A 332
GLY A 301
GLY A 337
GLY A 334
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wey NSP3
(SARS-CoV-2)		4 / 6
GLY A 250
GLY A 251
GLY A 255
GLY A 252
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
PRO F 309
GLY F 316
GLY E 284
GLY F 335
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR E 333
GLY E 335
PHE E 314
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ARG B 277
GLY B 287
LYS B 361
THR B 362
1.78A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR B 333
GLY B 335
PHE B 314
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.85A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wjt NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.96A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.00A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR B 112
GLY B 116
PHE B 110
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
TYR A 112
GLY A 116
PHE A 110
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		3 / 3
SER C 105
GLY C  60
GLY C 170
1.15A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 4
SER C6964
GLY C7006
GLY C6962
GLY C7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN D4315
GLN D4318
THR D4309
PRO D4312
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wkq NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
0.99A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO C6860
GLY C7076
GLY C6962
GLY C6963
1.16A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
SER C6964
GLY C6962
GLY C7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER A 288
GLY A 247
GLY A 239
0.92A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
SER B 288
GLY B 247
GLY B 239
0.94A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 254
PHE B 233
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 238
GLY B 239
PHE B 233
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR A 238
GLY A 254
PHE A 233
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR A 180
GLY A 126
PHE A 135
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
TYR B 180
GLY B 126
PHE B 135
1.53A
None
ACT  B 408 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.74A
None
None
U5G  A 401 (-3.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.12A
APR  D 201 (-3.5A)
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.07A
APR  B 201 (-3.4A)
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.07A
APR  C 201 (-3.9A)
APR  C 201 (-4.1A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.17A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.23A
None
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.17A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.09A
APR  A 201 (-3.9A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.06A
APR  D 201 (-3.8A)
APR  D 201 (-4.2A)
None
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.14A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
APR  D 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.29A
None
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.10A
APR  B 201 (-3.4A)
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.08A
APR  B 201 (-3.7A)
APR  B 201 (-4.0A)
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.12A
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
APR  D 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.28A
None
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.19A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.11A
APR  A 201 (-3.5A)
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.25A
None
APR  D 201 (-4.2A)
APR  D 201 (-3.5A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  51
GLY A  47
GLY A  48
GLY A  46
1.31A
None
APR  A 201 (-4.1A)
APR  A 201 (-3.5A)
APR  A 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.08A
APR  D 201 (-3.5A)
APR  D 201 (-4.2A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR D 152
GLY D   8
PHE D   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.07A
APR  A 201 (-3.5A)
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.14A
APR  B 201 (-4.0A)
APR  B 201 (-3.7A)
APR  B 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.08A
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY B  48
GLY B  46
1.26A
None
APR  B 201 (-4.0A)
APR  B 201 (-3.4A)
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.17A
APR  A 201 (-4.1A)
APR  A 201 (-3.9A)
APR  A 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
SER A 111
GLY A  79
GLY A  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.10A
APR  B 201 (-3.7A)
APR  B 201 (-4.0A)
None
APR  B 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.10A
APR  C 201 (-3.9A)
APR  C 201 (-4.1A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.08A
APR  D 201 (-3.8A)
APR  D 201 (-4.2A)
None
APR  D 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.11A
APR  C 201 (-3.5A)
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.12A
APR  A 201 (-3.9A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.15A
APR  C 201 (-4.1A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
SER A6964
GLY A6962
GLY A7076
0.84A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A7076
GLY A6962
GLY A6963
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		6wq3 NSP10
(SARS-CoV-2)		4 / 6
ASN B4315
GLN B4318
THR B4309
PRO B4312
1.68A
None
None
SO4  B4404 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 4
SER A6964
GLY A7006
GLY A6962
GLY A7076
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
PRO A6860
GLY A6962
GLY A7076
GLY A6963
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY B  11
GLY A  11
GLY A  15
0.99A12.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.39A19.87
None
None
None
DMS  A 406 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A  29
GLY A 120
GLY A  71
1.46A19.87
None
None
None
DMS  A 406 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.77A19.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
PRO A  39
GLY A  29
GLY A 120
GLY A 143
1.46A19.87
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE L 215
TYR L 192
PRO L 125
1.54A44.35
0.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
0.92A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.43
0.47
None
None
DMS  E 902 (-4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU B 163
TRP B 158
GLY B 143
1.33A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  24
GLY B  98
GLY B  35
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  24
GLY H  98
GLY H  35
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  35
GLY B  98
GLY B  99
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  28
GLY H  26
GLY H  24
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  99
GLY B  98
GLY B  35
0.92A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU B 163
TRP B 158
GLY B 143
1.29A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.30A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  24
GLY B  98
GLY B  35
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.34A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.06A
MLI  E 903 (-4.6A)
MLI  E 903 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO A 384
GLY B  99
GLY B 101
GLY A 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  35
GLY B  98
GLY B  99
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
None
MLI  E 903 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.23A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.20A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C  52
TRP B 109
GLY B  98
1.28A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C  52
TRP B 109
GLY B  98
1.25A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  28
GLY B  26
GLY B  24
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY E 502
TYR E 505
GLY E 504
ASP E 405
1.73A23.48
None
None
DMS  E 902 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  99
GLY B  98
GLY B  35
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  24
GLY H  98
GLY H  35
1.26A
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE C 215
TYR C 192
PRO C 125
1.52A44.35
0.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.12A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 412
GLY E 381
GLY E 431
GLY H 101
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6ym0 HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.36A11.67
6.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6ym0 HEAVY CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.40A11.67
6.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
1.09A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  28
GLY H  26
GLY H  24
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.43
0.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.24A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
GLY E 496
PHE E 497
PRO E 499
LYS E 444
1.67A9.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
PHE L 215
TYR L 192
PRO L 125
1.57A44.35
0.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  24
GLY H  98
GLY H  35
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
0.91A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.20A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 494
GLY A 496
GLY A 447
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.33A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER A 443
GLY A 447
GLY A 496
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  99
GLY B  98
GLY B  35
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.22A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCL_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
N-ACETYL-D-HIS-L-PRO
-OH)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 5
GLU E 406
PHE E 497
TYR E 508
PRO E 507
1.80A21.70
1.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU H 163
TRP H 158
GLY H 143
1.29A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO E 384
GLY H  99
GLY H 101
GLY E 381
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 443
GLY E 447
GLY E 496
1.13A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU B 163
TRP B 158
GLY B 143
1.29A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  35
GLY H  98
GLY H  99
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 6
PRO A 384
GLY B  99
GLY B 101
GLY A 381
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
(Homo
sapiens)		3 / 3
LEU B 163
TRP B 158
GLY B 143
1.33A12.15
6.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  99
GLY B  98
GLY B  35
0.91A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  24
GLY H  98
GLY H  35
1.25A
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE L 215
TYR L 192
PRO L 125
1.55A44.35
0.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  99
GLY H  98
GLY H  35
0.92A
None
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
PHE C 215
TYR C 192
PRO C 125
1.54A44.35
0.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  24
GLY B  98
GLY B  35
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  24
GLY H  98
GLY H  35
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
SER E 494
GLY E 496
GLY E 447
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  35
GLY B  98
GLY B  99
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C  52
TRP B 109
GLY B  98
1.18A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  28
GLY B  26
GLY B  24
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY A 502
TYR A 505
GLY A 504
ASP A 405
1.73A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  35
GLY B  98
GLY B  99
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO H  53
GLY H  28
GLY H  26
GLY H  24
1.05A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 6
PRO B  53
GLY B  24
GLY B  98
GLY B  35
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L  52
TRP H 109
GLY H  98
1.19A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 4
GLY E 502
TYR E 505
GLY E 504
ASP E 405
1.73A21.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C  52
TRP B 109
GLY B  98
1.22A10.00
6.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.31A
EPE  E 202 (-3.9A)
EPE  E 202 (-4.3A)
None
EPE  E 202 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER C 128
GLY C  97
GLY C 133
GLY C 130
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  51
GLY B  47
GLY E 130
1.30A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY E 133
GLY B  46
GLY B  47
GLY E 130
GLY B  51
1.76A
None
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY E 133
GLY E 130
1.06A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER D 128
GLY D  97
GLY D 133
GLY D 130
1.72A
None
None
None
EDO  D 205 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER E 128
GLY E  97
GLY E 133
GLY E 130
1.75A
EPE  E 202 (-4.6A)
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER A 128
GLY A  97
GLY A 133
GLY A 130
1.74A
EDO  A 202 (-4.3A)
EDO  A 202 ( 4.9A)
None
EDO  A 202 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.27A
EDO  D 209 ( 4.7A)
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.71A
EDO  C 203 (-4.8A)
EDO  C 203 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR D 152
GLY D   8
PHE D   6
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY E 133
GLY B  46
GLY B  48
1.24A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY E 133
GLY B  48
1.21A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY E 133
GLY E 130
GLY B  47
1.29A
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  47
GLY E 133
GLY B  48
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY B  51
GLY B  46
GLY E 130
GLY B  47
GLY E 133
1.64A
None
None
EPE  E 202 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY E 133
GLY B  47
GLY B  48
GLY B  46
GLY B  51
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY E 133
GLY B  46
GLY B  48
1.25A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  47
GLY B  51
GLY B  46
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY E 133
GLY E 130
GLY B  47
1.28A
None
None
EPE  E 202 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.27A
EDO  D 209 ( 4.7A)
EDO  D 206 (-4.5A)
EDO  D 206 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 130
GLY B  51
GLY E 133
GLY B  48
1.27A
EPE  E 202 ( 4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 6
GLY B  51
GLY B  46
GLY E 130
GLY B  47
GLY E 133
1.65A
None
None
EPE  E 202 ( 4.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.29A
EPE  E 202 ( 4.8A)
EPE  E 202 (-4.3A)
EPE  E 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY E 133
GLY E 130
1.12A
None
None
None
EPE  E 202 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  47
GLY B  51
GLY B  46
1.06A
None
APR  B 201 (-3.6A)
None
EDO  B 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.15A
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.31A
None
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  51
GLY D  47
GLY D  48
GLY D  46
1.28A
None
APR  D 201 ( 4.3A)
EDO  D 204 ( 3.4A)
APR  D 201 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.17A
EDO  D 204 ( 3.4A)
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  51
GLY E  47
GLY E  48
GLY E  46
1.29A
None
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.16A
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  48
GLY D  47
GLY D  46
GLY D  51
1.21A
EDO  D 204 ( 3.4A)
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  47
GLY E  46
GLY E  48
GLY E  51
1.12A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY E 133
GLY B  48
1.06A
None
EDO  B 202 (-3.9A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.11A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
EDO  D 204 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  47
GLY D  46
GLY D  48
GLY D  51
1.09A
APR  D 201 ( 4.3A)
APR  D 201 (-3.8A)
EDO  D 204 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  51
GLY E  47
GLY E  48
GLY E  46
1.31A
None
APR  E 201 (-4.4A)
APR  E 201 (-3.4A)
APR  E 201 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.07A
APR  E 201 (-3.9A)
APR  E 201 (-4.4A)
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.11A
APR  A 201 (-4.2A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.19A
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY B  47
GLY E 133
1.26A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.19A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.13A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  46
GLY A  47
GLY A  51
GLY A  48
1.08A
APR  A 201 (-4.2A)
APR  A 201 (-4.1A)
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  47
GLY C  46
GLY C  48
GLY C  51
1.11A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.07A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY B  47
GLY E 133
1.26A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.24A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E 133
GLY B  46
GLY B  47
GLY B  51
1.23A
None
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.25A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  46
GLY B  47
GLY B  51
GLY B  48
1.13A
EDO  B 202 (-3.9A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  46
GLY C  47
GLY C  51
GLY C  48
1.05A
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
PRO E 136
GLY B  51
GLY B  46
GLY E 133
1.25A
EDO  B 202 (-4.7A)
None
EDO  B 202 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
PRO E 136
GLY B  47
GLY B  51
GLY B  46
1.20A
EDO  B 202 (-4.7A)
APR  B 201 (-3.6A)
None
EDO  B 202 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.21A
APR  C 201 (-3.5A)
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.76A
None
EDO  C 204 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  47
GLY E  46
GLY E  48
GLY E  51
1.10A
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  46
GLY E  47
GLY E  51
GLY E  48
1.06A
APR  E 201 (-3.9A)
APR  E 201 (-4.4A)
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
SER B 111
GLY B  79
GLY B  97
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY E  48
GLY E  47
GLY E  46
GLY E  51
1.19A
APR  E 201 (-3.4A)
APR  E 201 (-4.4A)
APR  E 201 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.06A
APR  D 201 (-3.8A)
APR  D 201 ( 4.3A)
None
EDO  D 204 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR E 152
GLY E   8
PHE E   6
1.76A
None
EDO  E 203 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.17A
APR  C 201 (-3.5A)
APR  C 201 (-4.3A)
APR  C 201 (-4.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  47
GLY A  46
GLY A  48
GLY A  51
1.22A
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  51
GLY B  46
GLY E 133
GLY B  48
1.06A
None
EDO  B 202 (-3.9A)
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.21A
APR  A 201 (-3.4A)
APR  A 201 (-4.1A)
APR  A 201 (-4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  47
GLY B  46
GLY B  48
GLY B  51
1.28A
APR  B 201 (-3.6A)
EDO  B 202 (-3.9A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY D  46
GLY D  47
GLY D  51
GLY D  48
1.04A
APR  D 201 (-3.8A)
APR  D 201 ( 4.3A)
None
EDO  D 204 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY B  48
GLY B  47
GLY B  46
GLY B  51
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR B 152
GLY B   8
PHE B   6
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.26A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 4
SER B 128
GLY B  97
GLY B 133
GLY B 130
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR C 152
GLY C   8
PHE C   6
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY C  48
GLY C  47
GLY C  46
GLY C  51
1.26A
None
MES  C 201 ( 4.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
GLY A  48
GLY A  47
GLY A  46
GLY A  51
1.29A
None
MES  A 201 ( 4.8A)
MES  A 201 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
TYR A 152
GLY A   8
PHE A   6
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.79A
None
None
PJE  C   5 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
ARG A 197
GLY A 230
PRO A 227
THR A 225
1.70A3.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.01A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.50A1.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 786
TRP A 617
GLY A 616
1.75A4.05
1.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 925
GLY A 597
PHE A 594
1.19A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
TYR A 925
GLY A 596
PHE A 594
0.87A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 4
SER A 147
GLY A 146
GLY A 143
GLY A 120
1.80A
None
None
JRY  A 401 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
PRO A 122
GLY A 143
GLY A 146
GLY A  29
1.26A
None
JRY  A 401 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.02A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.90A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7bv1 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.49A1.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 597
PHE A 594
0.94A
None
None
C  T  15 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 595
GLY A 596
PHE A 594
1.05A
None
None
C  T  15 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.11A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
PRO A 232
GLY A 200
GLY A 228
GLY A 230
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		7bv2 NSP12
(SARS-CoV-2)		3 / 3
TYR A 831
PRO A 830
LEU A 829
1.54A1.04
None