Ligand ID: 6LH


Drugbank ID:
DB06795
(Mafenide)



Indication:
Mafenide is indicated in the treatment of severe burns.


Get human targets for 6LH in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '6LH'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.


DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
View Interface RMSD Seq.
Identity (%)
HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
1q2w 3C-LIKE PROTEASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
1q2w 3C-LIKE PROTEASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
1q2w 3C-LIKE PROTEASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.47A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.42A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.44A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.53A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.49A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2amd 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.62A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2amd 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.54A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2amd 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)
5 / 11
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.43A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)
5 / 11
HIS A   2
VAL A  74
LEU A  66
THR A  68
THR A  68
1.36A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)
5 / 9
HIS A   2
VAL A  74
LEU A  66
THR A  68
THR A  68
1.38A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)
5 / 9
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.47A20.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.53A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.61A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.57A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.59A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.51A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2qc2 3C-LIKE PROTEINASE
(-)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.50A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2qc2 3C-LIKE PROTEINASE
(-)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2qc2 3C-LIKE PROTEINASE
(-)
5 / 11
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.40A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
2vj1 MAIN PROTEINASE
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.48A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
2vj1 MAIN PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.53A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
2vj1 MAIN PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.57A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3avz 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.53A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3avz 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.44A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3avz 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3bgf F26G19 FAB
(Mus
musculus)
5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.64A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3bgf F26G19 FAB
(Mus
musculus)
5 / 11
GLU H 150
VAL H 121
VAL H 144
LEU H 154
THR H 153
1.49A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3e91 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3e91 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.44A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3e91 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.52A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.64A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.53A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.48A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.52A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)
5 / 10
GLN D 244
VAL D 247
LEU D 262
THR D 225
THR D 226
1.57A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.50A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.46A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.57A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.61A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.53A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.54A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.50A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.51A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.54A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6lze VIRAL PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6lze VIRAL PROTEASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6lze VIRAL PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6m0k VIRAL PROTEASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.76A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6m0k VIRAL PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6m2n 3CL PROTEASE
(SARS-CoV-2)
5 / 9
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.56A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6m2n 3CL PROTEASE
(SARS-CoV-2)
5 / 10
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.61A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6m2n 3CL PROTEASE
(SARS-CoV-2)
5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.67A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6m2n 3CL PROTEASE
(SARS-CoV-2)
5 / 9
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.54A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6m2n 3CL PROTEASE
(SARS-CoV-2)
5 / 11
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.50A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 11
GLU B  64
HIS B  94
VAL B  35
LEU B  88
THR B  57
1.80A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 11
HIS B  94
GLU B  64
VAL B  35
LEU B  88
THR B  57
1.78A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6wrh PEPTIDASE C16
(SARS-CoV-2)
5 / 11
GLN A  30
HIS A  50
VAL A  21
VAL A   7
THR A  34
1.75A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.59A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.61A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)
5 / 11
GLU D 155
VAL D 159
VAL D 186
LEU D 169
THR D 145
1.58A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)
5 / 11
GLU B 155
VAL B 159
VAL B 186
LEU B 169
THR B 145
1.59A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6yla LIGHT CHAIN
(Homo
sapiens)
5 / 11
GLN C   6
VAL C 110
LEU C  79
THR C  20
THR C  78
1.79A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
7bqy MAIN PROTEASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
7bqy MAIN PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
7bqy MAIN PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
7bqy MAIN PROTEASE
(SARS-CoV-2)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)
7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)
7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)
5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)
7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)
5 / 11
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)
7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)
5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A22.63
None