Ligand ID: BEP


Drugbank ID:
DB01244
(Bepridil)


Indication:
For the treatment of hypertension, and chronic stable angina (classic effort-associated angina).

Get human targets for BEP in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'BEP'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ILE B  91
PHE B  40
LEU B   9
LEU B  45
LEU B  88
1.29A18.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA F 912
ILE F 913
PHE F 909
PHE D 909
LEU F 920
1.47A26.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 11
LEU B  60
MET B  57
LEU F 108
VAL B  27
LEU B  76
1.58A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 12
ALA C  53
ILE C  44
LEU G 127
LEU C  61
LEU G 108
1.42A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		2ajf ACE2
(Homo
sapiens)		4 / 8
MET B 323
ASP B 350
ARG B 393
MET B 383
1.61A14.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 189
GLU A 166
ARG A 188
MET A  49
1.68A20.06
9IN  A1001 (-3.7A)
9IN  A1001 (-4.1A)
None
9IN  A1001 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
PHE B 287
ILE A 321
LEU A 332
LEU B 353
MET A 323
1.55A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		5 / 11
ILE C  20
LEU C  55
LEU D  53
LEU D  15
LEU D  47
1.65A18.12
D10  C1099 ( 4.8A)
None
D10  C1099 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE B 148
ILE B 152
LEU B 173
MET B 170
CYH B 261
1.41A13.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 11
LEU A  96
LEU A  53
VAL A 110
GLU A  44
LEU A  45
1.46A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2ghw SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA A 350
LEU A 374
PHE A 364
LEU A 421
LEU A 499
1.38A20.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
PHE B 287
ILE A 321
LEU A 332
LEU B 353
MET A 323
1.53A18.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 11
PHE A 287
ILE B 321
LEU B 332
LEU A 353
MET B 323
1.65A18.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		2gt8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 189
GLU A 166
ARG A 188
MET A  49
1.67A20.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr)		5 / 12
ILE A 322
LEU A 297
ILE A 305
GLU A 304
VAL A 320
1.42A14.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 12
ILE A 305
LEU A 227
PHE A 232
LEU A 250
MET A 209
1.51A19.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 12
ALA A 306
PHE A 308
PHE A 287
LEU A 292
PHE A 275
1.34A20.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE C 322
LEU C 297
ILE C 305
GLU C 304
VAL C 320
1.18A14.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE A 327
LEU A 331
PHE A 240
LEU A 250
LEU A 297
1.47A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 8
GLN D 130
PRO D 111
ASP D 124
ARG D 126
1.77A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE A 322
LEU A 297
ILE A 305
GLU A 304
VAL A 320
1.29A14.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE C 305
LEU C 227
PHE C 232
LEU C 250
MET C 209
1.41A19.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A 168
ILE A 128
MET A 184
LEU A 161
LEU A  59
1.38A18.69
None
None
None
None
NA  A1295 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A 168
ILE A 128
MET A 184
LEU A 161
LEU A  59
1.35A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		2z9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 110
PRO A 108
GLU A 240
GLU A 290
1.52A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
PHE A 525
ILE A 407
LEU A 529
LEU A 570
ILE A 544
1.63A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		3d0h SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE F 325
PHE F 451
LEU F 412
MET F 417
PHE F 387
1.42A18.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
PHE A 438
ILE A 291
VAL A 293
MET A 366
LEU A 410
1.29A14.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
GLU A 457
GLU A 467
ASP A 198
ARG A 192
1.57A14.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN B 110
PRO B 108
GLU B 240
GLU B 290
1.80A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		3e9s NSP3
(SARSr-CoV)		5 / 12
PHE A 148
ILE A 152
LEU A 173
MET A 170
CYH A 261
1.48A13.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 110
PRO A 108
GLU A 240
GLU A 290
1.69A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 189
GLU A 166
ARG A 188
MET A  49
1.62A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3i6g HLA, A-2
(Homo
sapiens)		4 / 8
GLN A 253
PRO A 250
GLU A 222
ASP A 220
1.71A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN B 189
ASP B 187
ARG B 188
MET B  49
1.64A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN B 110
PRO B 108
GLU B 240
GLU B 290
1.76A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
MET A 209
GLU A 204
GLU A 168
ASP B 165
1.70A17.74
GRM  B 801 (-4.1A)
None
None
GRM  B 801 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ALA A 168
ILE A 128
MET A 184
LEU A 161
LEU A  59
1.38A17.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		3scj ACE2
(Homo
sapiens)		5 / 12
PHE B 369
ILE B 307
LEU B 418
GLU B 312
MET B 376
1.64A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
PHE A  28
LEU A  97
LEU A  79
ILE A  88
GLU A  87
1.52A11.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
PHE B 438
ILE B 291
VAL B 293
MET B 366
LEU B 410
1.54A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
MET A 323
ASP A 350
ARG A 393
MET A 383
1.73A14.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		4m0w UBIQUITIN
(Bos
taurus)		5 / 12
PHE B  45
ILE B  61
LEU B  67
ILE B  23
GLU B  51
1.62A23.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr)		5 / 12
PHE A 148
ILE A 152
LEU A 173
MET A 170
CYH A 261
1.45A13.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
PHE B 148
ILE B 152
LEU B 173
MET B 170
CYH B 261
1.46A13.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		6 / 12
ILE A 126
PHE A 128
PHE A 148
LEU A 170
LEU A 311
LEU A 122
1.70A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 11
LEU A 204
LEU A 245
VAL A 129
LEU A 169
LEU A 170
1.49A17.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		4wy3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
GLN A 110
PRO A 108
GLU A 240
GLU A 290
1.77A20.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
PRO A   9
GLU B  14
ARG A   4
MET A   6
1.78A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
PHE D 198
ILE D 166
LEU D 109
VAL D 115
LEU D 185
1.63A14.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PHE D 514
ILE D 510
LEU D 442
LEU D 519
CYH D 340
1.64A10.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PHE D 514
ILE D 510
LEU D 442
LEU D 519
CYH D 340
1.60A10.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
PHE D 198
ILE D 166
LEU D 109
VAL D 115
LEU D 185
1.57A14.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE D 148
ILE D 152
LEU D 173
MET D 170
CYH D 261
1.51A13.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5e6j UBIQUITIN
(synthetic
construct)		5 / 12
PHE B  45
ILE B  61
LEU B  67
ILE B  23
GLU B  51
1.66A23.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
PHE B 198
ILE B 166
LEU B 109
VAL B 115
LEU B 185
1.60A15.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
PHE C 514
ILE C 510
LEU C 442
LEU C 519
CYH C 340
1.52A10.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5r83 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A  66
LEU A  87
MET A  82
GLU A  55
LEU A  57
1.62A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A  66
LEU A  87
MET A  82
GLU A  55
LEU A  57
1.64A19.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
ILE D 105
LEU D 114
LEU D 151
LEU D 174
LEU D 173
1.62A17.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
PHE D 148
ILE D 152
LEU D 173
MET D 170
CYH D 261
1.34A13.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		5x4r S PROTEIN
(MERS-CoV)		5 / 12
ILE A 296
PHE A 313
LEU A 180
LEU A 169
LEU A 149
1.30A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5x59 S PROTEIN
(MERS-CoV)		5 / 11
PHE B 571
ILE B 480
LEU B 415
LEU B 389
LEU B 488
1.58A8.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
GLN C1095
PRO C1094
GLU C1074
ARG B1073
1.73A8.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE A 219
PHE A 168
PHE A 187
LEU A 194
LEU A 222
1.29A8.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
ILE C 296
PHE C 313
LEU C 180
LEU C 169
LEU C 149
1.30A8.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		5x5f S PROTEIN
(MERS-CoV)		4 / 8
GLN C 544
PRO C 547
GLU C 549
ARG C 542
1.76A8.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA C 866
ILE A 687
PHE C 870
LEU C 788
LEU C 776
1.50A8.15
ALA  C 866 ( 0.0A)
ILE  A 687 ( 0.7A)
PHE  C 870 ( 1.3A)
LEU  C 788 ( 0.6A)
LEU  C 776 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
GLN B 549
PRO B 507
GLU B 569
ARG A  48
1.69A8.15
GLN  B 549 ( 0.6A)
PRO  B 507 ( 1.1A)
GLU  B 569 ( 0.5A)
ARG  A  48 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
PHE A 148
ILE A 152
LEU A 173
MET A 170
CYH A 261
1.40A13.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5yvd NSP15
(MERS-CoV)		5 / 12
ILE A 137
LEU A  72
ILE A 135
MET A 148
CYH A 189
1.39A15.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		5yvd NSP15
(MERS-CoV)		5 / 12
ILE B 137
LEU B  72
ILE B 135
MET B 148
CYH B 189
1.44A15.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		5 / 11
LEU B 941
LEU b   8
VAL a  13
LEU c   8
LEU C 948
1.59A21.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		5 / 12
ALA B 912
ILE B 913
PHE A 909
LEU c  32
LEU B 920
1.43A21.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
ILE C 652
LEU C 636
VAL C 675
GLU C 593
LEU C 283
1.53A8.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6acg ACE2
(Homo
sapiens)		5 / 12
ALA D 550
ILE D 544
MET D 408
LEU D 320
MET D 557
1.35A14.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
PRO B 507
GLU B 569
ASP B 564
ARG B 315
1.49A8.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6acg ACE2
(Homo
sapiens)		5 / 11
PHE D 438
ILE D 291
VAL D 293
MET D 366
LEU D 410
1.44A14.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 219
PHE A 168
PHE A 187
LEU A 194
LEU A 222
1.38A8.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6ack ACE2
(Homo
sapiens)		4 / 8
GLU D 457
GLU D 467
ASP D 198
ARG D 192
1.52A14.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
GLN B 835
PRO A 575
GLU B 821
ASP A 600
1.68A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE C 704
PHE C1034
PHE C 784
PHE C 888
MET C 884
1.45A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE C 187
ILE C  87
LEU C 194
ILE C  81
VAL C 254
1.67A5.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
PHE B 451
LEU B 412
MET B 417
VAL B 337
LEU B 499
1.59A8.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens;
SARSr-CoV)		4 / 8
MET A   5
GLU C   2
GLU A  55
ARG A  48
1.55A20.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6jyt HELICASE
(SARSr-CoV)		4 / 8
GLN B 548
PRO B 514
GLU B 551
ASP B 578
1.55A12.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ILE B 512
LEU B 405
ILE B 572
VAL B 544
CYH B 441
1.62A8.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE F1169
PHE F 970
PHE D 970
LEU F 959
LEU D 959
1.49A24.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6lzg ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
GLN B 493
GLU B 406
GLU A  37
ASP A  38
1.67A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m17 ACE2
(Homo
sapiens)		5 / 12
PHE D 369
ILE D 307
LEU D 418
GLU D 312
MET D 376
1.65A7.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE C  92
LEU C  96
LEU C  21
ILE C 107
VAL C 505
1.28A9.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PRO D 389
GLU D  37
GLU F 406
ASP F 405
1.55A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m17 ACE2
(Homo
sapiens)		5 / 11
PHE B 724
ILE B 618
VAL B 685
MET B 651
LEU D 642
1.52A11.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 11
LEU C 269
LEU C  77
VAL C 551
LEU C 540
LEU C 541
1.36A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
GLN A  94
GLU A  28
GLU A  20
MET A 521
1.52A13.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE C 219
LEU C 268
GLU C 288
LEU C 286
LEU C 287
1.66A18.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B  67
ILE B 132
LEU B  65
LEU B 162
GLU B  63
1.60A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6m3m NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO B  68
GLU B  63
ASP B  64
ARG B  90
1.50A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.65A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
LEU B 117
MET A 666
1.56A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.72A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
LEU B 117
MET A 666
MET B  94
1.73A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.41A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.61A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.61A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
ILE A 757
VAL A 587
MET A 601
1.78A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU A 270
VAL A 341
LEU A 387
LEU B 122
1.78A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.66A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.51A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.60A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.64A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.68A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.24A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.52A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  28
LEU C  14
MET C  62
LEU C  13
1.69A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  65
LEU C  71
PHE D  92
LEU C  56
LEU C  60
1.69A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
MET A 794
PHE A 753
LEU A 749
MET A 755
1.36A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 376
LEU A 401
LEU B 117
MET A 666
MET B  94
1.60A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU D  95
1.80A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
PHE B 784
ILE B 787
VAL B1047
MET B1032
LEU B 898
1.58A8.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_2
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES
TROPONIN I, CARDIAC
MUSCLE)		6nur NSP12
(SARSr-CoV)		4 / 4
ARG A 331
ILE A 333
ALA A 379
MET A 380
1.45A1.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6nur NSP7
NSP8
(SARSr-CoV)		5 / 12
PHE D  92
ILE D 107
LEU D  95
MET C  52
CYH C  32
1.66A17.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6nur NSP12
(SARSr-CoV)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.42A9.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.40A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6nur NSP12
(SARSr-CoV)		4 / 8
MET A 566
GLN A 524
ASP A 523
MET A 519
1.69A9.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6nur NSP7
NSP8
(SARSr-CoV)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.47A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6nus NSP12
(SARSr-CoV)		5 / 12
LEU A 673
LEU A 388
MET A 666
ILE A 539
GLU A 665
1.39A6.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 201
ILE C 231
LEU C 229
VAL C 130
LEU C 241
1.53A7.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLN B 644
GLU B 619
ASP B 614
ARG B 646
1.73A7.84
NAG  B1303 ( 4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vw1 ACE2
(Homo
sapiens)		5 / 11
PHE B 438
ILE B 291
VAL B 293
MET B 366
LEU B 410
1.48A14.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 306
LEU A 228
PHE A 233
LEU A 251
MET A 210
1.45A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 106
ILE C 235
LEU C 118
LEU C 242
LEU C 241
1.62A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE C 927
ILE C 931
LEU C1063
ILE C 818
GLU C 819
1.65A5.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
GLN C 563
PRO C 561
GLU A 224
ASP A  40
1.64A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE C 927
ILE C 931
LEU C1063
ILE C 818
GLU C 819
1.60A5.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 201
ILE C 231
LEU C 229
VAL C 130
LEU C 241
1.43A7.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
PRO A  67
GLU A  62
ASP A  63
ARG A  89
1.28A20.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A  66
ILE A 131
LEU A  64
LEU A 161
GLU A  62
1.56A18.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B 264
ILE B 281
LEU B 246
VAL B 295
LEU B 215
1.48A20.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 323
LEU A 298
ILE A 306
GLU A 305
VAL A 321
1.29A14.36
None
None
None
EDO  A 411 (-4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 377
PHE C 374
LEU C 513
LEU C 425
PHE C 400
1.68A18.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 377
LEU C 513
PHE C 429
LEU C 425
PHE C 400
1.76A18.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w4h NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.42A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w4h NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.47A19.93
None
None
None
BDF  A7105 (-3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.76A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6959
PHE A6985
MET A6982
1.80A22.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		6 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6981
MET A6982
LEU A6978
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6852
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.75A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.40A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.78A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6893
LEU A6883
1.77A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.49A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.64A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6893
LEU C6883
1.76A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.39A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.64A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
PHE C7003
LEU C6978
LEU C6959
1.79A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.73A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.46A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.48A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.74A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.73A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.77A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.56A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.44A21.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 147
ILE A 151
LEU A 172
MET A 169
CYH A 260
1.59A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE C 147
ILE C 151
LEU C 172
MET C 169
CYH C 260
1.67A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE B 147
ILE B 151
LEU B 172
MET B 169
CYH B 260
1.56A12.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ALA A  30
PHE A  56
LEU A 106
LEU A  88
PHE A  90
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA B 110
ILE A  68
LEU B 103
LEU B  91
LEU A  59
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  65
LEU A  71
PHE B  92
LEU A  56
LEU A  60
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.74A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 286
ILE D 320
LEU D 331
LEU C 352
MET D 322
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE E 286
ILE F 320
LEU F 331
LEU E 352
MET F 322
1.49A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D 286
LEU D 353
ILE D 292
GLU D 290
VAL D 270
1.56A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE F 286
ILE E 320
LEU E 331
LEU F 352
MET E 322
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE F 286
LEU F 353
ILE F 292
GLU F 290
VAL F 270
1.59A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 307
ILE C 337
LEU C 339
MET D 322
LEU C 291
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE D 286
ILE C 320
LEU C 331
LEU D 352
MET C 322
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C 286
LEU C 353
ILE C 292
GLU C 290
VAL C 270
1.61A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE E 286
ILE F 320
LEU F 331
LEU E 352
MET F 322
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B 286
ILE A 320
LEU A 331
LEU B 352
MET A 322
1.53A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE A 286
ILE B 320
LEU B 331
LEU A 352
MET B 322
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B 286
LEU B 353
ILE B 292
GLU B 290
VAL B 270
1.56A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D 286
ILE C 320
LEU C 331
LEU D 352
MET C 322
1.49A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE E 286
LEU E 353
ILE E 292
GLU E 290
VAL E 270
1.58A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 286
ILE A 320
LEU A 331
LEU B 352
MET A 322
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE A 286
ILE B 320
LEU B 331
LEU A 352
MET B 322
1.46A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE F 286
ILE E 320
LEU E 331
LEU F 352
MET E 322
1.60A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE A 286
LEU A 353
ILE A 292
GLU A 290
VAL A 270
1.62A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C 286
ILE D 320
LEU D 331
LEU C 352
MET D 322
1.52A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		6 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6981
MET A6982
LEU A6978
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.78A
None
None
FMT  A7107 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6997
ILE A7035
LEU A7042
LEU A6848
MET A6840
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE D  66
ILE D 131
LEU D  64
LEU D 161
GLU D  62
1.62A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO C  67
GLU C  62
ASP C  63
ARG C  89
1.42A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO B  67
GLU B  62
ASP B  63
ARG B  89
1.42A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE B  66
ILE B 131
LEU B  64
LEU B 161
GLU B  62
1.51A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PRO D  67
GLU D  62
ASP D  63
ARG D  89
1.56A21.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
PHE C  66
ILE C 131
LEU C  64
LEU C 161
GLU C  62
1.61A18.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
LEU C6978
MET C6982
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6925
LEU C6857
LEU C6887
LEU C6883
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
MET C6982
LEU C6959
LEU C6857
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C6926
LEU C6978
LEU C6959
MET C6982
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C7005
LEU C6848
LEU C7050
LEU C6893
LEU C6887
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C6951
LEU C6883
MET C6982
LEU C6855
LEU C6852
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA C6966
ILE C7005
LEU C6959
MET C6982
LEU C6978
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE C6955
LEU C6959
MET C6982
LEU C6855
LEU C6857
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6997
ILE A7035
LEU A7042
LEU A6848
MET A6840
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wkq NSP16
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE B 323
LEU B 298
ILE B 306
GLU B 305
VAL B 321
1.35A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 306
LEU A 228
PHE A 233
LEU A 251
MET A 210
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 323
LEU A 298
ILE A 306
GLU A 305
VAL A 321
1.32A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE B 303
ILE B 306
LEU B 298
ILE B 323
VAL B 321
1.49A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE B 306
LEU B 228
PHE B 233
LEU B 251
MET B 210
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE A 303
ILE A 306
LEU A 298
ILE A 323
VAL A 321
1.45A14.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6925
LEU A6857
LEU A6887
LEU A6883
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
LEU A6978
LEU A6959
MET A6982
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6857
1.70A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A6926
MET A6982
LEU A6959
LEU A6857
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
LEU A6978
MET A6982
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6955
LEU A6959
MET A6982
LEU A6855
LEU A6852
1.80A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A7005
LEU A6848
LEU A7050
LEU A6893
LEU A6887
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
ILE A6951
LEU A6883
MET A6982
LEU A6855
LEU A6852
1.43A
None
None
None
8NK  A7103 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6966
ILE A7005
LEU A6959
MET A6982
LEU A6978
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU A  56
MET A  52
LEU A  13
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE B  92
ILE B 107
LEU B  95
MET A  52
LEU A  17
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU A  55
MET A  52
LEU B 103
VAL A  22
LEU A  71
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE D  92
ILE D 107
LEU D  95
MET C  52
CYH C  32
1.72A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU D  95
MET C  52
LEU C  17
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  55
MET C  52
LEU D 103
LEU C  71
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
LEU C  56
MET C  52
LEU C  13
MET D  90
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.68A22.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU C  56
MET C  52
LEU C  13
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU D  98
LEU C  56
LEU C  13
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU B  98
LEU A  56
LEU A  13
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
PHE A 147
ILE A 151
LEU A 172
MET A 169
CYH A 260
1.62A12.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
LEU C  13
MET C  52
LEU D 103
VAL C  16
MET D  90
1.63A24.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU D  98
LEU C  56
LEU C  13
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA C  65
LEU C  71
PHE D  92
LEU C  13
LEU C  17
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
LEU A  56
MET A  52
LEU A  13
MET B  90
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU C  60
LEU C  17
LEU C  20
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU C  71
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
PHE D  92
ILE D 107
LEU D  95
MET C  52
LEU C  17
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
LEU C  56
MET C  52
LEU C  13
MET D  90
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE B  92
ILE B 107
LEU B  95
MET A  52
CYH A  32
1.72A23.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ALA A  48
ILE A  39
LEU B 122
LEU A  56
LEU B 103
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE C  39
MET B  94
LEU C  56
MET C  52
LEU C  13
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU B  98
LEU A  56
LEU A  13
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
PHE D  92
ILE D 107
LEU D  95
MET C  52
CYH C  32
1.66A23.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
ILE A  39
MET D  94
LEU A  56
MET A  52
LEU A  13
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 377
PHE E 374
PHE E 429
LEU E 425
PHE E 400
1.74A
None
DMS  E 901 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 434
LEU A 368
LEU A 387
GLU A 340
VAL A 511
1.53A16.18
None
None
DMS  A 905 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 377
PHE A 374
PHE A 429
LEU A 425
PHE A 400
1.73A
None
DMS  A 901 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE E 377
PHE E 374
PHE E 429
LEU E 425
PHE E 400
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE E 434
LEU E 368
LEU E 387
GLU E 340
VAL E 511
1.57A16.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		4 / 8
MET A 566
GLN A 524
ASP A 523
MET A 519
1.75A10.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_2
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES
TROPONIN I, CARDIAC
MUSCLE)		7btf NSP12
(SARS-CoV-2)		4 / 4
ARG A 331
ILE A 333
ALA A 379
MET A 380
1.74A2.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 652
ILE A 307
LEU A 351
ILE A 632
GLU A 658
1.66A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 145
LEU A 212
MET A 124
LEU A 207
GLU A 180
1.67A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.53A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
VAL A 848
LEU A 838
LEU A 883
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
LEU A 731
LEU A 470
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
LEU C  55
MET C  52
LEU D 103
VAL C  22
LEU D  95
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 863
ILE A 888
PHE A 881
PHE A 594
MET A 924
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
MET A 756
ILE A 757
VAL A 587
1.77A6.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 688
ILE A 589
PHE A 480
LEU A 575
LEU A 576
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU A 270
VAL A 341
LEU A 387
LEU B 122
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
ILE A 757
VAL A 587
MET A 601
1.78A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
ALA C  48
ILE C  39
LEU D 122
LEU C  56
LEU D 103
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 287
LEU A 316
LEU A 241
VAL A 320
GLU A 180
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.18A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 11
ILE D 119
LEU C  14
MET C  62
LEU D  95
LEU C  13
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 888
LEU A 891
MET A 855
ILE A 856
VAL A 860
1.53A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 745
LEU A 749
LEU A 707
ILE A 696
VAL A 476
1.54A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
MET A 566
GLN A 524
ASP A 523
MET A 519
1.71A10.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ILE B 107
LEU B 103
VAL A 330
LEU B  91
LEU B  95
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_2
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES
TROPONIN I, CARDIAC
MUSCLE)		7bv2 NSP12
(SARS-CoV-2)		4 / 4
ARG A 331
ILE A 333
ALA A 379
MET A 380
1.55A2.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 757
PHE A 694
PHE A 753
LEU A 749
MET A 755
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  94
MET A 666
LEU B 117
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP8
(SARS-CoV-2)		5 / 12
ILE B 107
LEU B 103
LEU B  95
ILE B 106
VAL B 115
1.47A17.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 589
LEU A 758
MET A 756
ILE A 757
VAL A 587
1.76A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
LEU A 885
VAL A 848
LEU A 838
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
ALA A 777
PHE A 782
MET A 755
LEU A 708
LEU A 707
PHE A 745
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
LEU A 630
MET A 633
LEU A 308
VAL A 785
LEU A 731
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
LEU B 117
MET B  94
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 145
LEU A 212
MET A 124
LEU A 207
LEU A 241
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 702
PHE A 782
LEU A 749
PHE A 745
LEU A 727
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 779
PHE A 753
MET A 755
LEU A 786
PHE A 694
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE A 539
PHE A 504
MET B  90
MET A 666
LEU B 117
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
LEU A 673
LEU A 388
MET A 666
ILE A 539
GLU A 665
1.55A7.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA A 375
MET B  90
LEU A 401
LEU B 117
MET B  94
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 688
ILE A 589
PHE A 480
LEU A 575
LEU A 576
1.70A
F86  P 102 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ILE A 856
LEU A 891
VAL A 848
LEU A 838
LEU A 883
1.59A
None