Ligand ID: POD


Drugbank ID:
DB01179
(Podofilox)


Indication:
For treatment of external genital warts (Condyloma acuminatum).

Get human targets for POD in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'POD'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
CYH B  14
ALA B  28
LEU B  45
ALA B  43
VAL B  41
1.37A13.78
18.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 268
ALA A 267
LEU A 271
MET A 276
ALA A 211
1.52A22.17
20.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1uw7 NSP9
(SARS-COV
HKU-39849)		5 / 12
CYH A  14
ALA A  28
LEU A  45
ALA A  43
VAL A  41
1.48A15.30
18.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL F1157
LEU A 927
ALA A 926
LYS A 929
LEU A 930
1.25A12.67
16.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B1268
ALA B1267
LEU B1208
VAL B1261
ALA B1260
1.50A22.17
21.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL J   9
LEU I  27
ALA I  26
LYS I  29
LEU I  30
1.52A6.21
6.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
LEU A 268
ALA A 267
LEU A 271
MET A 276
ALA A 211
1.52A21.93
20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
LEU D 194
ALA D 199
LEU D 192
VAL D 337
ALA D 336
1.36A17.46
17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL F1158
LEU C 927
ALA C 926
LYS C 929
LEU C 930
1.50A8.46
6.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
LEU C  13
ALA C  18
LEU C  11
VAL C 156
ALA C 155
1.37A16.81
17.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL C 221
LEU C 254
ASN C 216
ALA C 247
ALA C 250
1.43A21.79
21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL E 354
CYH C 378
LEU C 377
LEU C 374
ALA E 350
1.33A20.00
16.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
LEU A 268
ALA A 267
LEU A 271
MET A 276
ALA A 211
1.51A22.03
20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		2w2g NSP3
(SARSr-CoV)		5 / 12
VAL B 611
LEU B 648
ALA B 621
VAL B 641
ALA B 640
1.54A19.31
18.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 268
ALA A 267
LEU A 208
VAL A 261
ALA A 260
1.52A21.95
21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		5 / 12
VAL S 389
LEU S 355
LEU S 421
VAL S 328
ALA S 331
1.50A19.85
16.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
CYH C  14
ALA C  28
LEU C  45
ALA C  43
VAL C  41
1.45A11.97
13.15
None
None
GOL  C 123 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU A 268
ALA A 267
LEU A 271
MET A 276
ALA A 211
1.55A22.49
20.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 268
ALA B 267
LEU B 208
VAL B 261
ALA B 260
1.55A23.11
20.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		3sci SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL E 389
LEU E 355
LEU E 421
VAL E 328
ALA E 331
1.52A19.65
16.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 221
LEU A 254
ASN A 216
ALA A 247
ALA A 250
1.42A21.13
21.54
None
GOL  A 406 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
VAL A 221
LEU A 254
ASN A 216
ALA A 247
ALA A 250
1.35A21.96
21.84
None
None
None
P85  B 902 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
LEU B 268
ALA B 267
LEU B 271
MET B 276
ALA B 211
1.54A21.91
21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 12
VAL A 108
CYH B  39
LEU B  38
VAL B  29
ALA B  23
1.49A16.70
14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL D 221
LEU D 254
ASN D 216
ALA D 247
ALA D 250
1.33A21.96
21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		5 / 12
VAL B  14
LEU A  21
LEU A  18
ASN A  15
ALA B  22
1.41A11.31
11.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
VAL C 172
ALA C 233
LEU C 235
ALA C 250
ALA C  91
1.55A16.32
16.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
ALA A1130
LEU A 894
VAL A1026
LYS A1021
ALA A1025
1.53A14.95
16.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 221
LEU A 254
ASN A 216
ALA A 247
ALA A 250
1.47A21.85
21.79
None
GOL  A 407 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL C1076
LEU B 898
MET B 882
VAL C1111
ALA C1069
1.47A16.68
16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6acj ACE2
(Homo
sapiens)		5 / 12
LEU D 560
ALA D 396
ASN D 394
VAL D 404
ALA D 403
1.53A20.85
21.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL B 389
LEU B 355
LEU B 421
VAL B 328
ALA B 331
1.38A16.81
17.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ALA A 321
LYS A 323
LEU A 325
ALA A 296
ALA A 292
1.36A20.23
21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
VAL B1176
LEU C 945
ALA C 944
LYS C 947
LEU C 948
1.54A16.13
16.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m1d ACE2
(Homo
sapiens)		5 / 12
ALA D 550
LEU D 554
ASN D 556
MET D 557
ALA D 528
1.31A19.61
20.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.56A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ALA B 125
LEU B 128
ALA A 400
VAL A 398
ALA A 382
1.64A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.57A18.72

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6m71 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.67A20.51

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.55A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.49A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.51A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.57A
NHE  B 203 (-4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w02 NSP3
(SARS-CoV-2)		5 / 12
LEU A  12
LYS B  11
LEU A  10
VAL A 155
ALA A 154
1.37A17.19
18.79
None
None
None
APR  A 201 ( 4.6A)
APR  A 201 (-4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w4b NSP9
(SARS-CoV-2)		5 / 12
CYH A  15
ALA A  29
LEU A  46
ALA A  44
VAL A  42
1.39A14.21
19.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w4h NSP16
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.37A20.39
20.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.41A16.59
17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 NSP10
(SARS-CoV-2)		5 / 12
LEU B4328
ALA B4277
LYS B4281
VAL B4274
ALA B4273
1.75A17.21
15.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
LEU A6961
ALA A6960
ASN A7083
ALA A7056
ALA A6858
1.40A16.59
17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.52A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.65A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 124
LEU B 123
VAL B  49
ALA B  38
1.78A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
ALA B 112
VAL B  95
ALA B  38
1.79A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.72A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 124
LEU A 123
VAL A  49
ALA A  38
1.72A15.32
20.74
None
None
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.41A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  89
1.77A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 100
LEU A 153
LEU A 127
ALA A  38
VAL A  49
1.80A15.32
20.74
None
None
None
AMP  A 201 ( 3.9A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  27
1.67A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 165
LEU B  12
LEU B  10
VAL B 155
ALA B 154
1.50A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  89
1.75A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  88
ALA B  27
ASN B   4
VAL B  36
ALA B 124
1.80A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 124
LEU B 123
VAL B  49
ALA B  38
1.76A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.51A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
LEU A 126
ALA A 129
LEU A 127
VAL A  49
1.72A15.32
20.74
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.41A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.68A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 124
LEU A 123
VAL A  49
ALA A  38
1.71A15.32
20.74
None
None
None
AMP  A 201 ( 3.7A)
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.74A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.43A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
ALA A 112
VAL A  95
ALA A  38
1.78A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  77
ALA B 129
LEU B 127
ALA B  38
VAL B  49
1.80A15.32
20.74
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
LYS B  19
ASN B  20
VAL B  49
1.66A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
ALA B 112
VAL B  95
ALA B  38
1.78A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  89
1.77A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.56A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
LEU A 109
ALA A 112
LEU A 127
ALA A  38
1.79A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  34
LEU B 109
ALA B 112
ALA B 124
ALA B  38
1.80A15.32
20.74
None
None
None
None
MES  B 201 ( 3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  34
LEU A 109
ALA A 112
ALA A 124
ALA A  38
1.77A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 122
ALA B 124
LEU B  93
ASN B  37
ALA B  27
1.65A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.64A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.57A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B  88
ALA B  27
ASN B   4
VAL B  36
ALA B 124
1.80A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A 165
LEU B  12
LEU B  10
VAL B 155
ALA B 154
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  89
1.75A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  34
LEU A 109
ALA A 112
ALA A 124
ALA A  38
1.78A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
LEU A 109
ALA A 112
LEU A 127
ALA A  38
1.77A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.39A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
LEU A 126
ALA A 129
LEU A 127
VAL A  49
1.70A15.32
20.74
None
AMP  A 201 ( 4.4A)
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  77
ALA A 129
LEU A 127
ALA A  38
VAL A  49
1.79A15.32
20.74
None
AMP  A 201 ( 3.4A)
None
AMP  A 201 ( 3.9A)
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
ALA A 154
LYS A  19
ASN A  20
VAL A  49
1.72A15.32
20.74
None
AMP  A 201 ( 4.5A)
None
None
AMP  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A15.32
20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
ALA A 112
VAL A  95
ALA A  38
1.80A15.32
20.74
None
None
None
None
AMP  A 201 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ALA C6802
LYS C6799
ALA C6997
VAL C6995
ALA C6832
1.66A16.37
15.84
None
None
None
None
FMT  C7111 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C7087
LEU C6961
ALA C6960
ASN C6920
VAL C7057
1.67A16.37
15.84
None
None
None
FMT  C7106 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C7087
LEU C6961
ALA C6960
ASN C6920
VAL C7057
1.72A16.37
15.84
None
None
None
FMT  C7106 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
LEU C 125
LEU C 178
ALA C 204
VAL C 242
LYS C 182
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
CYH C 148
LEU C 152
ALA C 149
ALA C 135
ALA C 144
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
CYH A  14
ALA A  28
LEU A  45
ALA A  43
VAL A  41
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
CYH A  14
ALA A  28
LEU A  45
ALA A  43
VAL A  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.56A
None
None
None
MES  A 201 ( 4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 207
LEU A 327
ASN A 208
ALA A 293
LYS A 294
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
LEU A 357
ALA A 328
LEU A 326
ALA A 231
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 207
LEU A 327
ASN A 208
ALA A 293
LYS A 294
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
LEU A 357
ALA A 328
LEU A 326
ALA A 231
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
ALA A 260
ALA A 293
VAL A 239
LYS A 235
ALA A 231
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
ALA A 328
LEU A 326
VAL A 234
ALA A 231
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 286
ALA A 328
LEU A 326
VAL A 234
ALA A 231
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL A  53
LEU B 189
ALA B 126
LEU B 128
ALA B 152
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ALA A6802
LYS A6798
ALA A6997
VAL A6995
ALA A6832
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  33
ALA B  86
LEU C  40
ASN C  37
VAL A  16
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL A  53
LEU B 189
ALA B 126
LEU B 128
ALA B 152
1.68A
EDO  B 302 ( 4.8A)
None
None
None
EDO  B 302 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  33
ALA B  86
LEU C  40
ASN C  37
VAL A  16
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL C  53
LEU D 189
ALA D 126
LEU D 128
ALA D 152
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL B 130
LEU A  13
LEU A  56
VAL A  66
ALA A  65
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL D 130
LEU C  13
LEU C  56
VAL C  66
ALA C  65
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  35
ALA E 112
LEU E 127
ALA E  39
VAL E  41
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.52A
None
None
EDO  A 202 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.63A
None
EDO  E 205 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.53A
None
None
EDO  A 202 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B   3
LEU B 123
ASN B   4
ALA B  89
LYS B  90
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B   3
LEU B 123
ASN B   4
ALA B  89
LYS B  90
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 122
ALA C 124
LEU C  93
ASN C  37
ALA C  27
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.60A
None
EDO  E 205 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  49
CYH D 143
LEU D 127
ALA D 124
VAL D 151
1.43A
EDO  D 209 (-4.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  77
LEU D 126
ALA D 129
LEU D 127
VAL D  49
1.67A
None
APR  D 201 (-4.5A)
APR  D 201 (-3.4A)
None
APR  D 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  77
LEU B 126
ALA B 129
LEU B 127
VAL B  49
1.68A
None
APR  B 201 (-4.7A)
APR  B 201 (-3.6A)
None
APR  B 201 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.58A
None
APR  E 201 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
ALA B  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  35
ALA D 112
LEU D 127
ALA D  39
VAL D  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL E  82
LEU E 153
ALA E 124
LEU E 122
VAL E  30
ALA E  27
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
LEU D 153
ALA D 124
LEU D 122
ALA D  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU E 153
ALA E 154
ALA E  27
VAL E  30
LYS E  28
1.60A
None
APR  E 201 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA E  56
ALA E  89
VAL E  35
LYS E  31
ALA E  27
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  35
ALA C 112
LEU C 127
ALA C  39
VAL C  41
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  35
ALA E 112
LEU E 127
ALA E  39
VAL E  41
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  82
ALA D 124
LEU D 122
VAL D  30
ALA D  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA B  56
ALA B  89
VAL B  35
LYS B  31
ALA B  27
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU D 122
ALA D 124
LEU D  93
ASN D  37
ALA D  27
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.59A
EDO  B 203 ( 4.6A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  35
ALA B 112
LEU B 127
ALA B  39
VAL B  41
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  77
LEU C 126
ALA C 129
LEU C 127
VAL C  49
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
LEU A 153
ALA A 124
LEU A 122
ALA A  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU A 122
ALA A 124
LEU A  93
ASN A  37
ALA A  27
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  77
LEU C 126
ALA C 129
LEU C 127
VAL C  49
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
ALA A  56
ALA A  89
VAL A  35
LYS A  31
ALA A  27
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  49
CYH A 143
LEU A 127
ALA A 124
VAL A 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
ALA C 124
LEU C 122
VAL C  30
ALA C  27
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  49
CYH C 143
LEU C 127
ALA C 124
VAL C 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		6 / 12
VAL B  82
LEU B 153
ALA B 124
LEU B 122
VAL B  30
ALA B  27
1.58A
EDO  B 203 ( 4.6A)
None
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  82
ALA A 124
LEU A 122
VAL A  30
ALA A  27
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  49
CYH B 143
LEU B 127
ALA B 124
VAL B 151
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU C 122
ALA C 124
LEU C  93
ASN C  37
ALA C  27
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
ALA B  27
VAL B  30
LYS B  28
1.62A
None
EDO  B 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  35
ALA A 112
LEU A 127
ALA A  39
VAL A  41
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  82
LEU C 153
ALA C 124
LEU C 122
ALA C  27
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
LEU B 153
ALA B 154
ALA B  27
VAL B  30
LYS B  28
1.60A
None
EDO  B 202 (-4.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A   3
LEU A 123
ASN A   4
ALA A  89
LYS A  90
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  56
VAL C  22
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 234
ALA A 185
LEU A 186
VAL A 128
ALA A 125
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 234
ALA A 185
LEU A 186
VAL A 128
ALA A 125
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL D 115
CYH C  32
LEU C  55
LEU C  59
VAL C  22
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		5 / 12
VAL C  53
LEU D 189
ALA D 125
LEU D 128
ALA D 152
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 128
LEU A 707
ALA A 706
LEU A 708
ALA A  46
1.60A
None