Ligand ID: 8MO


Drugbank ID:
DB00553
(Methoxsalen)


Indication:
For the treatment of psoriasis and vitiligo

Get human targets for 8MO in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '8MO'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2ghv SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 11
PHE C 325
VAL C 497
PHE C 329
ILE C 345
LEU C 421
PHE C 379
1.67A18.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 11
PHE B  29
ASN B  74
GLY B  55
ILE B  70
LEU B  79
1.31A17.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		6 / 10
ASN A 355
ILE A 358
GLY B 322
THR B 333
ILE A 338
LEU A 340
1.68A12.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		6 / 11
ASN A 355
ILE A 358
GLY B 322
THR B 333
ILE A 338
LEU A 340
1.69A12.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 10
VAL A 294
ILE A 252
GLY A 253
ILE A 235
PHE A 302
1.34A20.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 11
PHE A 315
PHE A 316
ILE B 338
THR A 330
LEU B 354
1.03A14.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		5 / 10
PHE B 316
ILE B 321
GLY B 322
THR B 333
LEU A 340
1.43A14.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
VAL C 294
ILE C 252
GLY C 253
ILE C 235
LEU C 248
1.42A21.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
VAL C 294
ILE C 252
GLY C 253
ILE C 235
PHE C 302
1.32A23.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 10
PHE A 137
ILE A 126
ILE A 152
LEU A 133
PHE A 148
1.32A20.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 11
PHE A 137
ILE A 126
ILE A 152
LEU A 133
PHE A 148
1.30A20.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 10
PHE B 198
GLY B 110
ILE B  87
LEU B 170
PHE B 183
1.29A23.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
PHE B 198
GLY B 110
ILE B  87
LEU B 170
PHE B 183
1.28A23.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
PHE B 198
GLY B 110
ILE B  87
LEU B 170
PHE B 183
1.29A23.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 10
PHE B 198
GLY B 110
ILE B  87
LEU B 170
PHE B 183
1.31A23.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 10
PHE A 198
GLY A 110
ILE A  87
LEU A 170
PHE A 183
1.37A23.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 11
PHE A 187
PHE A 231
PHE A 103
ILE A  87
GLY A  86
LEU A 194
1.64A19.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		6 / 11
PHE C 187
PHE C 231
PHE C 103
ILE C  87
GLY C  86
LEU C 194
1.71A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		5 / 10
PHE B 952
ASN C 951
ILE C 955
GLY C 953
LEU c   8
1.41A11.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
VAL A 628
ASN A 627
ILE A 637
GLY A 638
ILE A 584
1.22A17.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL A 628
ASN A 627
ILE A 637
GLY A 638
ILE A 584
1.19A17.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
PHE C 629
ILE C 656
GLY C 653
ILE C 299
LEU C 597
1.24A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
PHE A 629
ILE A 656
GLY A 653
ILE A 299
LEU A 597
1.17A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
PHE A 629
ILE A 656
GLY A 653
ILE A 299
LEU A 597
1.13A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
PHE A 629
ILE A 656
GLY A 653
ILE A 299
LEU A 597
1.11A17.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6jyt HELICASE
(SARSr-CoV)		5 / 10
PHE A 225
ILE A 195
GLY A 196
THR A 214
PHE A 200
1.29A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6jyt HELICASE
(SARSr-CoV)		5 / 11
PHE A 225
ILE A 195
GLY A 196
THR A 214
PHE A 200
1.29A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 11
PHE F 970
ILE D 973
GLY D 971
ILE D1169
LEU D 966
1.28A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 10
PHE A 970
ILE A1169
ILE B1169
LEU C 966
PHE B 970
1.08A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 10
PHE B 970
ILE B1169
ILE C1169
LEU A 966
PHE C 970
1.03A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lxt SPIKE PROTEIN S2,
SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 11
PHE A 970
ILE A1169
ILE B1169
LEU C 966
PHE B 970
1.09A14.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 11
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.53A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.52A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE B 374
VAL B 511
GLY B 339
ILE B 358
LEU B 513
1.47A17.67
None
None
NAG  B 601 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
ASN B 277
GLY B 278
THR B 280
ILE B 281
LEU B 271
1.73A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 10
ASN A 198
GLY A 200
THR A 225
ILE A  86
LEU A  90
1.67A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.63A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.48A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ASN A 198
GLY A 200
THR A 225
ILE A  86
LEU A  90
1.65A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.62A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.37A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
VAL A  96
PHE A 192
ILE A  86
LEU A  90
PHE A 222
1.53A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.62A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.67A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 222
PHE A 192
ILE A 201
GLY A 230
LEU A 205
1.78A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 10
ASN A 198
GLY A 200
THR A 225
ILE A  86
LEU A  90
1.66A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
VAL A  96
PHE A 192
ILE A  86
LEU A  90
PHE A 222
1.52A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 222
PHE A 192
ILE A 201
GLY A 230
LEU A 205
1.80A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
ASN A 198
GLY A 200
THR A 225
ILE A  86
LEU A  90
1.69A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 782
ASN A 695
ILE A 696
THR A 586
PHE A 753
1.73A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.53A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
PHE C 629
ILE C 656
GLY C 653
ILE C 299
LEU C 597
1.21A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
PHE C 629
ILE C 656
GLY C 653
ILE C 299
LEU C 597
1.14A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6nur NSP12
(SARSr-CoV)		5 / 10
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.25A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6nur NSP12
(SARSr-CoV)		5 / 11
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.29A19.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 11
PHE A 194
PHE A 106
PHE A 238
ILE A 119
GLY A 103
PHE A  92
1.78A16.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE C 643
ILE C 670
GLY C 667
ILE C 312
LEU C 611
1.32A16.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vww URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A 295
ILE A 253
GLY A 254
ILE A 236
PHE A 303
1.31A23.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 11
PHE A 194
PHE A  86
PHE A 106
ASN A 196
ILE A 128
LEU A 117
1.54A16.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE C 643
ILE C 670
GLY C 667
ILE C 312
LEU C 611
1.27A16.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE C 643
ILE C 670
GLY C 667
ILE C 312
LEU C 611
1.29A15.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE C 643
ILE C 670
GLY C 667
ILE C 312
LEU C 611
1.22A15.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY C 381
THR C 430
ILE L  28
LEU C 390
PHE C 392
1.75A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 374
VAL C 511
ILE C 358
LEU C 513
PHE C 338
1.69A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 338
GLY C 431
THR C 430
LEU C 387
PHE C 392
1.52A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 10
GLY C 381
THR C 430
ILE L  28
LEU C 390
PHE C 392
1.73A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 338
GLY C 431
THR C 430
LEU C 387
PHE C 392
1.58A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY C 381
THR C 430
ILE L  28
LEU C 390
PHE C 392
1.72A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 374
VAL C 511
GLY C 339
ILE C 358
LEU C 513
1.54A15.35
None
None
NAG  C 601 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 374
VAL C 511
ILE C 358
LEU C 513
PHE C 338
1.66A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 374
VAL C 511
ILE C 358
LEU C 513
PHE C 338
1.62A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 CR3022 FAB LIGHT
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 10
GLY C 381
THR C 430
ILE L  28
LEU C 390
PHE C 392
1.75A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 374
VAL C 511
GLY C 339
ILE C 358
LEU C 513
1.57A15.35
None
None
NAG  C 601 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 374
VAL C 511
GLY C 339
ILE C 358
LEU C 513
1.58A15.35
None
None
NAG  C 601 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 338
GLY C 431
THR C 430
LEU C 387
PHE C 392
1.52A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 338
GLY C 431
THR C 430
LEU C 387
PHE C 392
1.56A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 11
PHE C 374
VAL C 511
ILE C 358
LEU C 513
PHE C 338
1.66A15.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 10
PHE C 374
VAL C 511
GLY C 339
ILE C 358
LEU C 513
1.63A15.35
None
None
NAG  C 601 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE C 127
ILE C 151
ILE C 123
LEU C 125
PHE C 173
1.79A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
PHE C 173
THR C 119
ILE C 123
LEU C 125
PHE C 241
1.71A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
PHE A 173
THR A 119
ILE A 123
LEU A 125
PHE A 241
1.64A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE B 173
THR B 119
ILE B 123
LEU B 125
PHE B 241
1.71A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE B 127
THR B 119
ILE B 123
LEU B 125
PHE B 173
1.74A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 127
THR A 119
ILE A 123
LEU A 125
PHE A 173
1.76A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
PHE A 173
THR A 119
ILE A 123
LEU A 125
PHE A 241
1.66A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE C 127
THR C 119
ILE C 123
LEU C 125
PHE C 173
1.77A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 127
ILE A 151
ILE A 123
LEU A 125
PHE A 173
1.79A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 127
THR A 119
ILE A 123
LEU A 125
PHE A 173
1.77A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE C 127
THR C 119
ILE C 123
LEU C 125
PHE C 173
1.77A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE C 127
ILE C 151
ILE C 123
LEU C 125
PHE C 173
1.77A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE B 127
THR B 119
ILE B 123
LEU B 125
PHE B 173
1.75A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 173
THR A 119
ILE A 123
LEU A 125
PHE A 241
1.68A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
PHE B 173
THR B 119
ILE B 123
LEU B 125
PHE B 241
1.70A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
PHE B 173
THR B 119
ILE B 123
LEU B 125
PHE B 241
1.68A21.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 314
PHE C 315
ILE D 337
THR C 329
LEU D 353
1.45A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 315
ILE B 320
GLY B 321
THR B 332
ILE A 337
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN D 354
ILE D 357
THR C 332
ILE D 337
LEU D 339
1.60A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ILE B 357
GLY A 321
THR A 332
ILE B 337
LEU B 339
1.51A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE D 357
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN B 354
ILE B 357
THR A 332
ILE B 337
LEU B 339
1.62A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE F 314
PHE F 315
ILE E 337
THR F 329
LEU E 353
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
ASN A 354
ILE A 357
GLY B 321
THR B 332
ILE A 337
LEU A 339
1.67A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN E 354
ILE E 357
THR F 332
ILE E 337
LEU E 339
1.63A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 314
PHE B 315
ILE A 337
THR B 329
LEU A 353
1.53A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL E 350
ASN E 354
ILE E 357
THR F 332
LEU E 339
1.66A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN B 354
ILE B 357
THR A 332
ILE B 337
LEU B 339
1.62A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 314
PHE C 315
ILE D 337
THR C 329
LEU D 353
1.45A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN B 354
ILE B 357
THR A 332
ILE B 337
LEU B 339
1.64A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
VAL B 350
ASN B 354
ILE B 357
THR A 332
LEU B 339
1.61A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL B 350
ASN B 354
ILE B 357
THR A 332
LEU B 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 307
PHE A 315
ILE B 337
THR A 329
LEU B 353
1.73A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
VAL C 350
ASN C 354
ILE C 357
GLY D 321
THR D 332
LEU C 339
1.73A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE B 357
GLY A 321
THR A 332
ILE B 337
LEU B 339
1.50A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL D 350
ASN D 354
ILE D 357
THR C 332
LEU D 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
ASN C 354
ILE C 357
GLY D 321
THR D 332
ILE C 337
LEU C 339
1.61A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL D 350
ASN D 354
ILE D 357
THR C 332
LEU D 339
1.63A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN F 354
ILE F 357
GLY E 321
ILE F 337
LEU F 339
1.56A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL E 350
ASN E 354
ILE E 357
THR F 332
LEU E 339
1.63A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		7 / 10
VAL A 350
ASN A 354
ILE A 357
GLY B 321
THR B 332
ILE A 337
LEU A 339
1.75A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE F 314
PHE F 315
ILE E 337
THR F 329
LEU E 353
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE B 320
GLY B 321
THR B 332
ILE A 337
LEU A 339
1.79A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE B 314
PHE B 315
ILE A 337
THR B 329
LEU A 353
1.53A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
VAL F 350
ASN F 354
ILE F 357
GLY E 321
THR E 332
LEU F 339
1.73A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE E 307
PHE F 315
ILE E 337
THR F 329
LEU E 353
1.70A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		7 / 10
VAL C 350
ASN C 354
ILE C 357
GLY D 321
THR D 332
ILE C 337
LEU C 339
1.71A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
VAL A 350
ASN A 354
ILE A 357
GLY B 321
THR B 332
LEU A 339
1.77A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE E 357
GLY F 321
THR F 332
ILE E 337
LEU E 339
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ILE B 357
GLY A 321
THR A 332
ILE B 337
LEU B 339
1.49A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE C 320
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.80A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE A 307
PHE B 315
ILE A 337
THR B 329
LEU A 353
1.77A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
PHE B 315
ILE B 320
GLY B 321
THR B 332
ILE A 337
1.71A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN D 354
ILE D 357
THR C 332
ILE D 337
LEU D 339
1.62A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE F 307
PHE E 315
ILE F 337
THR E 329
LEU F 353
1.78A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE A 320
GLY A 321
THR A 332
ILE B 337
LEU B 339
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ILE D 357
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.49A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
ASN A 354
ILE A 357
GLY B 321
THR B 332
ILE A 337
LEU A 339
1.68A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE D 357
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
VAL B 350
ASN B 354
ILE B 357
THR A 332
LEU B 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE D 307
PHE C 315
ILE D 337
THR C 329
LEU D 353
1.75A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
VAL B 350
ASN B 354
ILE B 357
THR A 332
LEU B 339
1.62A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		7 / 11
VAL C 350
ASN C 354
ILE C 357
GLY D 321
THR D 332
ILE C 337
LEU C 339
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE F 320
GLY F 321
THR F 332
ILE E 337
LEU E 339
1.76A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
PHE C 315
ILE C 320
GLY C 321
THR C 332
ILE D 337
1.69A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN F 354
ILE F 357
GLY E 321
ILE F 337
LEU F 339
1.58A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN F 354
ILE F 357
GLY E 321
ILE F 337
LEU F 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN D 354
ILE D 357
THR C 332
ILE D 337
LEU D 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ASN B 354
ILE B 357
THR A 332
ILE B 337
LEU B 339
1.62A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE E 307
PHE F 315
ILE E 337
THR F 329
LEU E 353
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE D 320
GLY D 321
THR D 332
ILE C 337
LEU C 339
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE C 320
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.72A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
VAL F 350
ASN F 354
ILE F 357
GLY E 321
THR E 332
LEU F 339
1.71A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
VAL F 350
ASN F 354
ILE F 357
GLY E 321
THR E 332
LEU F 339
1.72A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
VAL C 350
ASN C 354
ILE C 357
GLY D 321
THR D 332
LEU C 339
1.75A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
ASN F 354
ILE F 357
GLY E 321
THR E 332
ILE F 337
LEU F 339
1.66A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
ASN C 354
ILE C 357
GLY D 321
THR D 332
ILE C 337
LEU C 339
1.64A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
VAL A 350
ASN A 354
ILE A 357
GLY B 321
THR B 332
LEU A 339
1.75A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE D 307
PHE C 315
ILE D 337
THR C 329
LEU D 353
1.71A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE A 314
PHE A 315
ILE B 337
THR A 329
LEU B 353
1.46A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE E 314
PHE E 315
ILE F 337
THR E 329
LEU F 353
1.48A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ILE B 357
GLY A 321
THR A 332
ILE B 337
LEU B 339
1.50A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ILE C 320
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.79A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE D 314
PHE D 315
ILE C 337
THR D 329
LEU C 353
1.50A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
ILE D 357
GLY C 321
THR C 332
ILE D 337
LEU D 339
1.46A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 11
PHE C 307
PHE D 315
ILE C 337
THR D 329
LEU C 353
1.74A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 10
VAL F 350
ASN F 354
ILE F 357
GLY E 321
THR E 332
LEU F 339
1.70A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
ASN A 354
ILE A 357
GLY B 321
THR B 332
ILE A 337
LEU A 339
1.64A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 11
VAL A 350
ASN A 354
ILE A 357
GLY B 321
THR B 332
LEU A 339
1.76A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 10
ASN D 354
ILE D 357
THR C 332
ILE D 337
LEU D 339
1.59A13.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A   8
ASN A  12
GLY A  14
LEU A  43
PHE A  56
1.40A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A 222
ILE A 253
ILE A 307
LEU A 228
PHE A 233
1.63A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A 233
VAL A 237
ILE A 307
ILE A 296
LEU A 251
1.72A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL B 295
ILE B 253
GLY B 254
ILE B 236
PHE B 303
1.38A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A   8
VAL A  11
ASN A  12
LEU A  43
PHE A  56
1.68A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B 222
ILE B 253
ILE B 307
LEU B 228
PHE B 233
1.60A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B   8
ASN B  12
GLY B  14
LEU B  43
PHE B  56
1.40A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A 233
VAL A 237
ILE A 307
ILE A 296
LEU A 251
1.67A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B   8
VAL B  11
ASN B  12
LEU B  43
PHE B  56
1.77A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B 233
VAL B 237
ILE B 307
ILE B 296
LEU B 251
1.75A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B   8
ASN B  12
GLY B  14
LEU B  43
PHE B  56
1.42A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A   8
ASN A  12
GLY A  14
LEU A  43
PHE A  56
1.38A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B   8
VAL B  11
ASN B  12
LEU B  43
PHE B  56
1.69A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B   8
VAL B  11
ASN B  12
LEU B  43
PHE B  56
1.70A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL B 295
ILE B 253
GLY B 254
ILE B 236
PHE B 303
1.32A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B   8
VAL B  11
ASN B  12
LEU B  43
PHE B  56
1.71A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A   8
ASN A  12
GLY A  14
LEU A  43
PHE A  56
1.38A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B 233
VAL B 237
ILE B 307
ILE B 296
LEU B 251
1.70A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A   8
VAL A  11
ASN A  12
LEU A  43
PHE A  56
1.68A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A   8
ASN A  12
GLY A  14
LEU A  43
PHE A  56
1.40A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A 295
ILE A 253
GLY A 254
ILE A 236
PHE A 303
1.33A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A   8
VAL A  11
ASN A  12
LEU A  43
PHE A  56
1.70A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A 295
ILE A 253
GLY A 254
ILE A 236
PHE A 303
1.35A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE B   8
ASN B  12
GLY B  14
LEU B  43
PHE B  56
1.43A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B 222
ILE B 253
ILE B 307
LEU B 228
PHE B 233
1.60A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 295
ILE A 253
GLY A 254
ILE A 236
PHE A 303
1.34A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL B 295
ILE B 253
GLY B 254
ILE B 236
PHE B 303
1.34A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL B 295
ILE B 253
GLY B 254
ILE B 236
PHE B 303
1.34A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE B   8
ASN B  12
GLY B  14
LEU B  43
PHE B  56
1.41A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
VAL A 295
ILE A 253
GLY A 254
ILE A 236
PHE A 303
1.39A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 11
PHE A 222
ILE A 253
ILE A 307
LEU A 228
PHE A 233
1.62A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
PHE A   8
VAL A  11
ASN A  12
LEU A  43
PHE A  56
1.76A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.62A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.66A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.66A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.61A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.61A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.64A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL D 115
ILE C  68
ILE D 107
LEU C  60
PHE D  92
1.64A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 10
VAL D 115
ILE C  68
ILE D 107
LEU C  60
PHE D  92
1.64A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.65A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 11
VAL D 115
ILE C  68
ILE D 107
LEU C  60
PHE D  92
1.66A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 10
PHE A 173
THR A 119
ILE A 123
LEU A 125
PHE A 241
1.69A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
PHE A 173
THR A 119
ILE A 123
LEU A 125
PHE A 241
1.71A21.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.69A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.72A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 10
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.66A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 10
VAL B 115
ILE A  68
ILE B 107
LEU A  60
PHE B  92
1.68A11.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A  13
VAL A  32
PHE A  70
ASN A  35
ILE A 106
1.62A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A  13
VAL A  32
PHE A  70
ASN A  35
ILE A 106
1.66A16.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.60A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.71A17.63
None
None
None
DMS  A 905 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.44A17.63
DMS  A 901 (-4.3A)
None
NAG  A 904 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.67A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.61A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.42A17.63
DMS  E 901 (-4.4A)
None
NAG  E 907 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.63A17.63
DMS  A 901 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.59A17.63
DMS  A 901 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.67A17.63
None
None
None
DMS  A 905 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.45A17.63
DMS  E 901 (-4.4A)
None
NAG  E 907 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.66A17.63
DMS  E 901 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.47A17.63
DMS  A 901 (-4.3A)
None
NAG  A 904 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.79A17.65
None
None
None
None
DMS  E 901 (-4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.62A17.63
DMS  E 901 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
GLY B  28
THR B  31
ILE A 434
LEU A 368
PHE A 374
1.78A17.65
None
None
None
None
DMS  A 901 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.53A17.63
DMS  A 901 (-4.3A)
None
NAG  A 904 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.63A17.63
None
None
None
DMS  A 905 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.59A17.63
DMS  E 901 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.44A17.63
DMS  E 901 (-4.4A)
None
NAG  E 907 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY B  28
THR B  31
ILE A 434
LEU A 368
PHE A 374
1.76A17.65
None
None
None
None
DMS  A 901 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.63A17.63
None
None
None
DMS  A 905 ( 4.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.62A17.63
DMS  E 901 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.48A17.63
DMS  A 901 (-4.3A)
None
NAG  A 904 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.66A17.63
DMS  A 901 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.65A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.63A17.63
DMS  A 901 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.51A17.63
DMS  E 901 (-4.4A)
None
NAG  E 907 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.70A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.67A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.67A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.53A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.63A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.72A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.60A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.72A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.67A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.74A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.72A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.50A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.74A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.68A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.54A17.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.70A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.42A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.65A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.67A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.45A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.62A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.65A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.60A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.65A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.59A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.65A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.44A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.61A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 338
GLY A 431
THR A 430
LEU A 387
PHE A 392
1.63A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.51A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.62A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
GLY E 339
ILE E 358
LEU E 513
1.51A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.62A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.44A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.45A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.59A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 338
GLY E 431
THR E 430
LEU E 387
PHE E 392
1.60A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE E 374
VAL E 511
ILE E 358
LEU E 513
PHE E 338
1.59A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY H  28
THR H  31
ILE E 434
LEU E 368
PHE E 374
1.79A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
GLY B  28
THR B  31
ILE A 434
LEU A 368
PHE A 374
1.79A17.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
PHE A 374
VAL A 511
GLY A 339
ILE A 358
LEU A 513
1.42A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 11
PHE A 374
VAL A 511
ILE A 358
LEU A 513
PHE A 338
1.61A16.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.48A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 11
ASN A 277
GLY A 278
THR A 280
ILE A 281
LEU A 271
1.49A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.47A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.72A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.77A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.71A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 11
VAL A  96
PHE A 192
ILE A  86
LEU A  90
PHE A 222
1.52A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.70A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 11
VAL A  96
PHE A 192
ILE A  86
LEU A  90
PHE A 222
1.54A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7btf NSP12
(SARS-CoV-2)		5 / 10
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.30A18.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.75A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 222
PHE A 192
ILE A 201
GLY A 230
LEU A 205
1.80A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.45A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 11
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.74A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.70A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.41A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.35A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.80A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 10
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.79A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.68A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.71A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.75A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
VAL A  96
PHE A 192
ILE A  86
LEU A  90
PHE A 222
1.57A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.43A18.78
None
None
None
MG  A1005 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.67A18.78
None
U  T  10 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.67A18.78
None
U  T  10 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 313
VAL A 315
ILE A 466
LEU A 316
PHE A 287
1.31A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.69A18.78
None
U  T  10 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 506
VAL A 560
ILE A 562
THR A 567
ILE A 536
1.73A18.78
None
U  T  10 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.80A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 766
VAL A 764
PHE A 753
GLY A 616
PHE A 782
1.39A18.78
None
None
None
MG  A1005 ( 4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
PHE A 396
VAL A 398
ASN B 118
ILE A 539
LEU A 673
1.79A18.78
None