Ligand ID: MIL


Drugbank ID:
DB00235
(Milrinone)


Indication:
Indicated for the treatment of congestive heart failure.

Get human targets for MIL in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'MIL'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU E1167
LEU E 920
SER E 919
0.89A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		1wyy E2 GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU B1167
LEU B 920
SER B 919
0.80A20.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU D  19
LEU E  20
SER E  19
0.83A14.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU E1168
LEU C 920
SER C 919
0.86A16.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		3 / 3
LEU B 170
LEU B 174
SER B 178
1.05A12.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.71A22.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.74A22.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		3 / 3
LEU A 745
LEU A 986
SER A 985
1.15A7.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5x5f S PROTEIN
(MERS-CoV)		3 / 3
LEU C 344
LEU C 347
SER C 350
0.98A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU A 636
LEU A 597
SER A 582
0.78A7.29
LEU  A 636 ( 0.6A)
LEU  A 597 ( 0.6A)
SER  A 582 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		3 / 3
LEU a  25
LEU A 920
SER A 919
0.77A22.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU B 636
LEU B 597
SER B 582
0.53A7.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
LEU B 636
LEU B 597
SER B 582
0.74A7.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		3 / 3
LEU B 636
LEU B 597
SER B 582
0.69A7.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6jyt HELICASE
(SARSr-CoV)		3 / 3
LEU A  25
LEU A   7
SER A 100
1.13A13.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		3 / 3
LEU C1186
LEU C 938
SER C 937
0.85A20.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6lze VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.69A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.70A17.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU B 287
LEU B 271
SER B 267
1.71A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU B 287
LEU B 286
SER B 284
1.79A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU B 287
LEU B 271
SER B 267
1.71A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 271
SER A 267
1.69A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 271
SER A 267
1.70A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.73A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU C 287
LEU C 271
SER C 267
1.76A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m2q 3CL PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.79A17.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 308
LEU A 636
SER A 635
1.67A8.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m71 NSP12
(SARS-CoV-2)		3 / 3
LEU A 308
LEU A 636
SER A 635
1.68A8.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6m71 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.27A8.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6m71 NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.72A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m71 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.29A8.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6m71 NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.77A20.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		3 / 3
LEU A 636
LEU A 597
SER A 582
0.70A7.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6nur NSP7
(SARSr-CoV)		3 / 3
LEU C  17
LEU C  14
SER C  10
1.11A21.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU B 650
LEU B 611
SER B 596
0.90A8.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
LEU B 153
LEU B 126
SER B 139
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
LEU B 153
LEU B 126
SER B 139
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6vxs NSP3
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 650
LEU A 611
SER A 596
0.79A7.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU C 650
LEU C 611
SER C 596
0.78A7.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
LEU L 179
LEU L 181
SER L 182
1.78A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
LEU L 181
LEU L 179
SER L 159
1.45A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
LEU L 179
LEU L 181
SER L 182
1.74A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		3 / 3
LEU L 181
LEU L 179
SER L 159
1.45A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w4h NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.95A16.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.96A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7010
SER A7074
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w6y NSP3
(SARS-CoV-2)		3 / 3
LEU B 153
LEU B 126
SER B 139
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7010
SER C7074
1.64A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.34A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.48A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.31A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.38A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.96A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.48A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.46A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.28A21.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.74A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.73A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.99A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.49A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.96A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.74A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w75 NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.99A22.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
LEU C 253
LEU C 282
SER C 293
1.29A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
LEU C 253
LEU C 282
SER C 293
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
LEU B 253
LEU B 282
SER B 293
1.22A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		3 / 3
LEU B 253
LEU B 282
SER B 293
1.20A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wcf NSP3
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wey NSP3
(SARS-CoV-2)		3 / 3
LEU A 364
LEU A 368
SER A 371
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wey NSP3
(SARS-CoV-2)		3 / 3
LEU A 364
LEU A 368
SER A 371
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wiq NSP7
(SARS-CoV-2)		3 / 3
LEU A  35
LEU A  55
SER A  10
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wiq NSP7
(SARS-CoV-2)		3 / 3
LEU A  35
LEU A  55
SER A  10
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.99A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7010
SER C7074
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.31A
FMT  B4403 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.37A
FMT  B4403 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.95A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU C6852
LEU C6857
SER C6964
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C6852
LEU C6857
SER C6964
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A6852
LEU A6857
SER A6964
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU D4298
LEU C7042
SER C7041
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.97A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7073
SER C7074
0.95A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7072
SER A7071
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7010
SER C7074
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C6961
LEU C7073
SER C7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7010
SER A7074
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.99A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP10
NSP16
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wkq NSP16
(SARS-CoV-2)		3 / 3
LEU C7078
LEU C7072
SER C7071
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU A 249
LEU A 246
SER A 288
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU B 249
LEU B 246
SER B 288
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU B 249
LEU B 246
SER B 288
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		3 / 3
LEU A 249
LEU A 246
SER A 288
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.95A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7073
SER A7074
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		3 / 3
LEU B4298
LEU A7042
SER A7041
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A6961
LEU A7010
SER A7074
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		3 / 3
LEU A7078
LEU A7073
SER A7074
0.98A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		3 / 3
LEU A  35
LEU A  55
SER A  10
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wqd NSP7
(SARS-CoV-2)		3 / 3
LEU A  35
LEU A  55
SER A  10
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		3 / 3
LEU A 253
LEU A 282
SER A 293
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6wrh PEPTIDASE C16
(SARS-CoV-2)		3 / 3
LEU A 253
LEU A 282
SER A 293
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		3 / 3
LEU A  35
LEU A  55
SER A  10
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C 187
LEU C 185
SER C 165
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C 185
LEU C 187
SER C 188
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C 185
LEU C 187
SER C 188
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
LEU E 452
SER E 349
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU C 187
LEU C 185
SER C 165
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
LEU E 452
SER E 349
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yla LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 492
LEU A 452
SER A 349
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU H 128
LEU H 145
SER L 137
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
LEU E 452
SER E 349
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ym0 LIGHT CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 492
LEU A 452
SER A 349
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C 185
LEU C 187
SER C 188
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU A 492
LEU A 452
SER A 349
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
LEU E 452
SER E 349
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C 185
LEU C 187
SER C 188
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		3 / 3
LEU E 492
LEU E 452
SER E 349
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C 187
LEU C 185
SER C 165
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L 185
LEU L 187
SER L 188
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU C 187
LEU C 185
SER C 165
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6yor IGG L CHAIN
(Homo
sapiens)		3 / 3
LEU L 187
LEU L 185
SER L 165
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 153
LEU C 126
SER C 139
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 160
LEU B 164
SER B 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 160
LEU D 164
SER D 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 160
LEU D 164
SER D 167
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU E 153
LEU E 126
SER E 139
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 153
LEU D 126
SER D 139
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 153
LEU B 126
SER B 139
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU E 160
LEU E 164
SER E 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 153
LEU D 126
SER D 139
1.53A
None
APR  D 201 (-4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.51A
None
APR  A 201 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 160
LEU C 164
SER C 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 153
LEU C 126
SER C 139
1.52A
None
APR  C 201 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 160
LEU D 164
SER D 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU E 160
LEU E 164
SER E 167
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 153
LEU B 126
SER B 139
1.52A
None
APR  B 201 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU D 160
LEU D 164
SER D 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU E 153
LEU E 126
SER E 139
1.52A
None
APR  E 201 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 160
LEU C 164
SER C 167
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 160
LEU B 164
SER B 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 160
LEU B 164
SER B 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 153
LEU A 126
SER A 139
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 160
LEU B 164
SER B 167
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 160
LEU C 164
SER C 167
1.79A
EDO  C 203 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU B 160
LEU B 164
SER B 167
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 160
LEU A 164
SER A 167
1.78A
None
None
EDO  A 206 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU C 160
LEU C 164
SER C 167
1.79A
EDO  C 203 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		3 / 3
LEU A 160
LEU A 164
SER A 167
1.78A
None
None
EDO  A 206 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP7
(SARS-CoV-2)		3 / 3
LEU C  17
LEU C  14
SER C  10
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 308
LEU A 636
SER A 635
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP12
NSP8
(SARS-CoV-2)		3 / 3
LEU B  95
LEU B  98
SER A 384
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP12
(SARS-CoV-2)		3 / 3
LEU A 308
LEU A 636
SER A 635
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7btf NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP7
(SARS-CoV-2)		3 / 3
LEU C  17
LEU C  14
SER C  10
1.03A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7btf NSP12
NSP8
(SARS-CoV-2)		3 / 3
LEU B  95
LEU B  98
SER A 384
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		3 / 3
LEU A 287
LEU A 286
SER A 284
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU D  91
LEU C  13
SER C  10
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP7
NSP8
(SARS-CoV-2)		3 / 3
LEU D  91
LEU C  13
SER C  10
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  17
LEU C  14
SER C  10
1.08A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP12
NSP8
(SARS-CoV-2)		3 / 3
LEU B  95
LEU B  98
SER A 384
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  35
LEU C  55
SER C  10
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  59
LEU C  13
SER C  10
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  56
LEU C  13
SER C  10
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.24A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  56
LEU C  13
SER C  10
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 575
LEU A 638
SER A 635
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 575
LEU A 638
SER A 635
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP7
(SARS-CoV-2)		3 / 3
LEU C  17
LEU C  14
SER C  10
1.07A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv1 NSP12
(SARS-CoV-2)		3 / 3
LEU A 389
LEU A 388
SER A 672
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv2 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.10A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv2 NSP12
NSP7
(SARS-CoV-2)		3 / 3
LEU A 838
LEU A 437
SER C   4
1.06A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_B_MILB128_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		7bv2 NSP12
(SARS-CoV-2)		3 / 3
LEU A 207
LEU A 240
SER A 239
1.51A
None