Ligand ID: LLT


Drugbank ID:
DB01265
(Telbivudine)


Indication:
For the treatment of chronic hepatitis B in adult and adolescent patients ≥16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Get human targets for LLT in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'LLT'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.65A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A1170
LEU A1174
GLN C 917
LEU C1174
1.52A19.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL B1247
LEU B1250
TYR B1209
LEU B1268
1.29A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.65A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2ajf ACE2
(Homo
sapiens)		4 / 7
GLU A 171
VAL A 132
LEU A 148
LEU A 162
1.39A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
GLU F1177
LEU A 920
GLN A 915
LEU D1175
1.42A11.03
None
None
None
ACE  B 913 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.55A20.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
VAL C 304
LEU C 254
TYR C 297
GLN C 123
1.50A21.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 7
GLU B  46
VAL B  48
LEU B  81
LEU B  86
1.48A19.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		4 / 7
GLU A  46
VAL A  49
LEU A  53
LEU A  10
1.49A19.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.63A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.66A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.62A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.64A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		2wct NSP3
(SARSr-CoV)		4 / 7
GLU B 403
VAL D 553
TYR D 583
PHE B 406
1.49A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3bgf F26G19 FAB
(Mus
musculus)		4 / 7
LEU L 179
TYR L 192
GLN L 124
LEU L 125
1.38A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLU A 375
MET A 323
PHE A 327
MET A 360
ALA A 372
1.59A19.53
 ZN  A 901 (-3.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
GLU A 232
VAL A 581
LEU A 520
TYR A 516
1.30A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.62A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 7
VAL A 297
LEU A 253
PHE A   3
LEU A 282
1.42A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL B 125
PHE A 150
MET B   6
ALA A 116
GLU B  14
1.64A19.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.67A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3i6g HLA, A-2
MEMBRANE PROTEIN
(Homo
sapiens)		4 / 7
GLU D 154
LEU C   1
TYR A   7
LEU A 160
1.35A23.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.68A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.66A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 10
GLU A 203
LEU A 239
GLN A  49
LEU A 244
GLU A  32
1.38A24.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3scj ACE2
(Homo
sapiens)		4 / 7
GLU B 232
VAL B 581
LEU B 520
TYR B 516
1.30A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 7
GLU A 232
VAL A 581
LEU A 520
TYR A 516
1.26A18.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
GLU B 375
MET B 323
PHE B 327
MET B 360
ALA B 372
1.53A19.53
 ZN  B 901 (-3.6A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		3snd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL B 125
PHE A 150
MET B   6
ALA A 116
GLU B  14
1.59A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL B 125
PHE A 150
MET B   6
ALA A 116
GLU B  14
1.67A20.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL B 125
PHE A 150
MET B   6
ALA A 116
GLU B  14
1.62A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		5c5o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
VAL A 125
PHE B 150
MET A   6
ALA B 116
GLU A  14
1.62A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
GLU B 302
VAL B 305
PHE B 401
ALA B 425
PHE B 426
1.67A19.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
GLU A 264
VAL A 301
LEU A 212
LEU A 283
1.50A22.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.65A18.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 7
VAL D 304
LEU D 254
TYR D 297
GLN D 123
1.42A22.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5tl7 REPLICASE
POLYPROTEIN 1AB
UBIQUITIN-LIKE
PROTEIN ISG15
(Mus
musculus;
SARSr-CoV)		4 / 7
GLU A  87
LEU A 152
TYR B 274
LEU B 212
1.45A16.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 7
GLU A 900
VAL A 897
TYR A1049
GLN A 904
1.20A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5x5c S PROTEIN
(MERS-CoV)		4 / 7
VAL B 575
LEU B 441
TYR B 409
LEU B 415
1.34A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
GLU A 900
VAL A 897
TYR A1049
GLN A 904
1.44A12.44
GLU  A 900 ( 0.6A)
VAL  A 897 ( 0.6A)
TYR  A1049 ( 1.3A)
GLN  A 904 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 7
VAL A 304
LEU A 254
TYR A 297
GLN A 123
1.43A22.32
None
GOL  A 408 (-4.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		6acj ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 10
GLU D  35
LEU C 472
PHE D  32
LEU D  97
GLU D  75
1.77A18.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6acj ACE2
(Homo
sapiens)		5 / 12
GLU D 375
MET D 323
PHE D 327
MET D 360
ALA D 372
1.56A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A1076
TYR C 899
GLN C1018
LEU C1031
1.26A12.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLU B 162
VAL B 124
ARG B 126
ALA B 127
PHE B 130
1.46A12.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 7
GLU C 900
VAL C 897
TYR C1049
GLN C 904
1.06A12.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6cs2 ACE2
(Homo
sapiens)		5 / 12
GLU D 375
MET D 323
PHE D 327
MET D 360
ALA D 372
1.62A19.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLU A 162
VAL A 124
ARG A 126
ALA A 127
PHE A 130
1.69A12.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6jyt HELICASE
(SARSr-CoV)		4 / 7
VAL B 496
LEU B 500
PHE B 511
LEU B 528
1.25A18.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 297
LEU A 253
PHE A   3
LEU A 282
1.80A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.62A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.62A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 297
LEU A 253
PHE A   3
LEU A 282
1.77A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_A_LLTA261_1
(DEOXYCYTIDINE KINASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 10
GLU C 405
VAL C 402
LEU C 398
LEU C 389
GLU C 394
1.75A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 7
GLU F 484
GLN F 493
PHE F 490
LEU F 452
1.47A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m18 ACE2
(Homo
sapiens)		4 / 7
GLU D 232
VAL D 581
LEU D 520
TYR D 516
1.28A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 7
GLU A 405
VAL A 402
LEU A 398
LEU A 389
1.49A16.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
VAL A 125
PHE C 150
MET A   6
ALA C 116
GLU A  14
1.67A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
VAL C 125
PHE A 150
MET C   6
ALA A 116
GLU C  14
1.67A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL D 247
LEU D 250
TYR D 209
LEU D 268
1.67A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
GLU B 240
VAL B 202
LEU B 250
LEU B 227
1.70A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
VAL D 125
PHE B 150
MET D   6
ALA B 116
GLU D  14
1.69A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
VAL B 125
PHE D 150
MET B   6
ALA D 116
GLU B  14
1.68A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.65A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL B 247
LEU B 250
TYR B 209
LEU B 268
1.64A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL C 247
LEU C 250
TYR C 209
LEU C 268
1.64A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.62A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
VAL A 720
LEU A 775
TYR A 770
LEU A 749
1.67A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
VAL A 182
LEU A 245
GLN A 210
LEU A 207
1.78A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
VAL A 704
LEU A 731
TYR A 732
GLN A 789
1.47A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLU A 658
LEU A 636
PHE A 571
LEU A 575
1.63A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLU A 436
VAL A 435
TYR A 884
PHE A 429
1.43A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6m71 NSP12
(SARS-CoV-2)		4 / 7
GLU A 876
LEU A 883
TYR A 884
LEU A 437
1.76A15.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 7
VAL A 718
LEU A 986
GLN A 993
LEU A 994
1.50A12.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L 184
TYR L 197
GLN L 129
LEU L 130
1.44A21.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL C 785
LEU C 877
GLN C 779
LEU C 865
1.35A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
VAL C 785
LEU C 877
GLN C 779
LEU C 865
1.38A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L  47
TYR L  86
GLN L  79
LEU L  78
1.60A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 7
LEU L 179
TYR L 192
GLN L 124
LEU L 125
1.59A21.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w4h NSP16
(SARS-CoV-2)		4 / 7
GLU A7001
LEU A7037
GLN A6847
LEU A7042
1.38A21.28
ACT  A7103 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
GLU A7001
LEU A7037
GLN A6847
LEU A7042
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w6y NSP3
(SARS-CoV-2)		4 / 7
GLU A  25
VAL A  24
LEU A  53
PHE A 156
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w75 NSP16
(SARS-CoV-2)		4 / 7
GLU C7001
LEU C7037
GLN C6847
LEU C7042
1.45A17.51
FMT  C7108 ( 3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU C 282
TYR C 296
GLN C 122
LEU C 118
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 7
LEU C 253
GLN C 122
PHE C 304
LEU C 118
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		4 / 7
LEU A  -8
TYR A  31
PHE A  75
LEU A 103
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
GLU A  -7
VAL A  -6
TYR A  32
GLN A  11
ALA A  -9
1.72A21.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wiq NSP7
NSP8
(SARS-CoV-2)		4 / 7
VAL A  16
LEU A  20
PHE B  92
LEU A  71
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
GLU C7001
LEU C7037
GLN C6847
LEU C7042
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
GLU A7001
LEU A7037
GLN A6847
LEU A7042
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wkq NSP16
(SARS-CoV-2)		4 / 7
GLU C7001
LEU C7037
GLN C6847
LEU C7042
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wkq NSP16
(SARS-CoV-2)		4 / 7
GLU A7001
LEU A7037
GLN A6847
LEU A7042
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 7
VAL A 304
LEU A 228
PHE A 342
LEU A 312
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 7
GLU A7001
LEU A7037
GLN A6847
LEU A7042
1.40A
GTA  A7102 (-4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B 125
PHE A 150
MET B   6
ALA A 116
GLU B  14
1.67A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.65A20.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		4 / 7
VAL L 139
LEU H 128
GLN L 130
LEU L 131
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L 185
TYR L 198
GLN L 130
LEU L 131
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU C 185
TYR C 198
GLN C 130
LEU C 131
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLU E 484
GLN E 493
PHE E 490
LEU E 452
1.49A
None
MLI  E 903 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
GLU L  87
LEU L  84
GLN L  43
LEU L  53
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
GLU C  87
LEU C  84
GLN C  43
LEU C  53
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
VAL L  64
LEU L  53
TYR L  92
LEU L  84
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 7
VAL C  64
LEU C  53
TYR C  92
LEU C  84
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
VAL L  64
LEU L  53
TYR L  92
LEU L  84
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 7
LEU L 185
TYR L 198
GLN L 130
LEU L 131
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
GLU A 240
VAL A 202
LEU A 250
LEU A 227
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
LEU L 185
TYR L 198
GLN L 130
LEU L 131
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
VAL L  64
LEU L  53
TYR L  92
LEU L  84
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLU A 484
GLN A 493
PHE A 490
LEU A 452
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 7
GLU E 484
GLN E 493
PHE E 490
LEU E 452
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
LEU C 185
TYR C 198
GLN C 130
LEU C 131
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
GLU C  87
LEU C  84
GLN C  43
LEU C  53
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
VAL C  64
LEU C  53
TYR C  92
LEU C  84
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yor IGG L CHAIN
(Homo
sapiens)		4 / 7
GLU L  87
LEU L  84
GLN L  43
LEU L  53
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  95
LEU D 127
TYR D 113
GLN A 118
1.58A
None
None
None
EDO  D 201 ( 4.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  95
LEU A 127
TYR A 113
GLN D 118
1.60A
None
EDO  A 202 ( 4.8A)
None
EDO  D 201 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL D  95
LEU D 127
TYR D 113
GLN A 118
1.56A
None
None
None
EDO  D 203 (-3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  95
LEU A 127
TYR A 113
GLN D 118
1.59A
None
None
None
EDO  A 207 ( 4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL C  95
LEU C 127
TYR C 113
GLN A 118
1.55A
None
None
None
EDO  A 202 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 7
VAL A  95
LEU A 127
TYR A 113
GLN C 118
1.54A
None
None
None
EDO  A 204 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
VAL A 190
LEU A 187
PHE A 287
LEU A 282
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
VAL A 704
LEU A 731
TYR A 732
GLN A 789
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
VAL A 720
LEU A 775
TYR A 770
LEU A 749
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLU A 136
LEU A 142
TYR A 175
PHE A 793
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLU A 658
LEU A 636
PHE A 571
LEU A 575
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
LEU A 280
TYR A 294
PHE A 321
LEU A 251
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7btf NSP12
(SARS-CoV-2)		4 / 7
GLU A 254
LEU A 186
TYR A 238
PHE A 317
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 297
LEU A 253
PHE A   3
LEU A 282
1.80A
None
None
None
DMS  A 404 (-4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 7
VAL A 247
LEU A 250
TYR A 209
LEU A 268
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLU A 658
LEU A 636
PHE A 571
LEU A 575
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
VAL A 720
LEU A 775
TYR A 770
LEU A 749
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
VAL A 704
LEU A 731
TYR A 732
GLN A 789
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
LEU A 280
TYR A 294
PHE A 321
LEU A 251
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
GLU A 254
LEU A 186
TYR A 238
PHE A 317
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 7
VAL A 190
LEU A 187
PHE A 287
LEU A 282
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL B 159
LEU B 184
TYR B 138
LEU A 389
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
VAL A 190
LEU A 187
PHE A 287
LEU A 282
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLU A 136
LEU A 142
TYR A 175
PHE A 793
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
VAL A 720
LEU A 775
TYR A 770
LEU A 749
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
GLU A 658
LEU A 636
PHE A 571
LEU A 575
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 7
VAL A 704
LEU A 731
TYR A 732
GLN A 789
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 7
VAL A 338
LEU B  95
GLN B  88
LEU A 371
1.61A
None