Ligand ID: RIM


Drugbank ID:
DB00478
(Rimantadine)


Indication:
For the prophylaxis and treatment of illness caused by various strains of influenza A virus in adults.

Get human targets for RIM in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'RIM'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.38A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY A  29
SER A 121
ALA A 116
SER A 123
SER A 144
1.56A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		1uk2 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY A  29
SER A 121
ALA A 116
SER A 123
SER A 144
1.57A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL B 934
ALA B 938
SER B1156
ALA A 938
VAL A 934
1.26A28.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU B1184
LEU B1181
ASP B1180
ILE A 905
1.40A27.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.31A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL E  34
ALA E  38
SER D   8
ALA C  38
VAL C  34
1.26A18.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 10
ALA G  19
SER G  16
ALA G  23
SER G  46
SER G  52
1.45A8.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		4 / 6
LEU G 100
LEU G 103
ILE G 112
ARG G 101
1.64A9.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2ajf ACE2
(Homo
sapiens)		4 / 6
ILE B 223
ARG B 219
LEU B 222
ASP B 201
1.41A7.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL B 934
VAL C 934
ALA C 938
ALA F1156
VAL A 934
1.33A15.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU E1179
LEU F1182
ASP F1181
ILE B 916
1.61A25.93
None
None
ACE  B 913 ( 3.7A)
ACE  B 913 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		2bx3 MAIN PROTEINASE
(SARS-COV
Sin2774)		4 / 6
SER A 144
SER A 121
ALA A 116
SER A 123
1.43A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		4 / 6
ILE F 305
LEU F 354
LEU F 292
ASP F 289
1.42A15.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 9
ALA H 314
SER H 313
GLY H 317
SER H 311
ALA G 306
1.39A10.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY B  11
ALA A   7
ALA B   7
VAL B 114
SER B 113
1.56A6.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.41A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2dd8 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
ILE S 345
ARG S 342
LEU S 499
ASP S 385
1.42A14.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		4 / 6
SER T  15
SER W  15
ALA N  18
ALA T  18
1.27A11.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 6
LEU A  66
LEU A  66
ASP A  64
ILE A  91
1.44A23.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 6
ILE B 207
ARG B 193
LEU B 210
LEU B 179
1.35A11.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 9
SER D 184
GLY D 196
ALA D 187
ALA D 166
ALA D 183
1.51A7.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		4 / 6
LEU B 210
LEU B 145
ILE B 207
ARG B 150
1.47A11.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2gib NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 6
ILE B 305
LEU B 354
LEU B 292
ASP B 289
1.37A17.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		4 / 6
LEU A 297
LEU A 298
ASP A 301
ILE A 322
1.31A11.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		2hob
REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV;
synthetic
construct)		5 / 10
ALA A 193
ALA A 194
ALA A 173
VAL A 186
ALA B   2
1.45A6.60
None
None
None
None
02J  B   1 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.37A9.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU B 297
LEU B 298
ASP B 301
ILE B 322
1.32A11.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.38A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
SER A 139
GLY A 138
SER B   1
GLY A 170
SER A 144
1.49A6.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.37A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.41A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		4 / 6
LEU B 297
LEU B 298
ASP B 301
ILE B 322
1.38A11.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.40A7.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		2wct NSP3
(SARSr-CoV)		5 / 9
SER B 461
GLY B 466
ALA B 493
ALA C 464
ALA B 464
1.31A6.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		2wct NSP3
(SARSr-CoV)		5 / 9
ALA B 493
ALA C 464
GLY C 466
ALA B 464
SER B 461
1.40A6.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		2wct NSP3
(SARSr-CoV)		5 / 10
VAL A 589
ALA A 590
SER A 591
ALA A 493
ALA D 464
1.44A9.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 9
GLY A  73
ALA A 107
VAL A 104
ALA A  79
SER A 105
1.74A6.41
SAH  A1293 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3avz 3C-LIKE PROTEINASE
PEPTIDE
ACE-SER-ALA-VAL-ALC-
HIS-H
(SARSr-CoV)		5 / 9
GLY A 183
ALA A 193
ALA B   3
VAL A 171
ALA A 173
1.58A6.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.37A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		3bgf F26G19 FAB
(Mus
musculus)		4 / 6
SER L  72
SER L  63
ALA L  51
SER L  52
1.22A9.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		3bgf F26G19 FAB
(Mus
musculus)		4 / 6
LEU L  33
LEU L  89
ILE L  48
ARG L  46
1.58A20.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3bgf SPIKE PROTEIN S1
(SARSr-CoV)		4 / 6
ILE A 345
ARG A 342
LEU A 499
ASP A 385
1.36A13.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
GLY H 104
ALA H  78
SER H  21
ALA H  24
SER H  77
1.58A8.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
SER A 545
SER A 411
ALA A 533
VAL A 318
SER A 547
1.46A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
ALA B 550
SER B 547
GLY B 551
SER B 411
SER B 545
1.52A4.24
None
None
None
None
NDG  B 619 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
SER B 411
SER B 545
ALA B 550
SER B 547
1.40A4.24
None
NDG  B 619 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3d62 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.39A9.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.41A9.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.35A9.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.38A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLY B  29
SER B 121
ALA B 116
SER B 123
SER B 144
1.65A6.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.41A9.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.36A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
LEU B  87
LEU B  86
ILE B  43
ARG B  40
1.59A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		4 / 6
LEU F   9
LEU D  95
ASP D  74
ILE F   7
1.57A23.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.40A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.41A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.36A9.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
LEU B  87
LEU B  86
ILE B  43
ARG B  40
1.54A9.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		6 / 10
VAL B 206
ALA B 205
VAL B 203
SER A  79
ALA B 182
SER B 181
1.77A10.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 10
VAL A 104
ALA A  79
ALA A  72
SER A  98
ALA A 107
SER A 109
1.76A10.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 9
GLY A  73
SER A  98
GLY A  71
ALA A 107
SER A 105
1.55A5.81
SAM  A 302 (-4.1A)
None
SAM  A 302 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 9
GLY A  73
ALA A 107
VAL A 104
ALA A  79
SER A 105
1.68A5.81
SAM  A 302 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		4 / 6
SER A  98
ALA A 107
ALA A  79
SER A 105
1.42A5.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		3sci ACE2
(Homo
sapiens)		4 / 6
SER A  43
ALA A  71
SER A  70
ALA A  65
1.23A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3scj ACE2
(Homo
sapiens)		5 / 9
SER B 545
SER B 411
ALA B 533
VAL B 318
SER B 547
1.50A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
SER B 545
SER B 411
ALA B 533
VAL B 318
SER B 547
1.52A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
ILE B 446
ARG B 518
LEU B 450
LEU B 410
1.32A6.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 6
SER A 411
SER A 545
ALA A 550
SER A 547
1.37A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.43A9.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		3vb4 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.29A6.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.39A8.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.40A7.00
None
DMS  A 403 ( 4.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.37A8.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 9
GLY B  88
ALA B  85
ALA B  79
VAL B 282
ALA B 281
1.50A3.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
LEU D 117
LEU D 157
ILE D 166
ARG D 163
1.28A7.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 9
GLY D  88
ALA D  85
ALA D  79
VAL D 282
ALA D 281
1.49A3.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		4 / 6
LEU B 117
LEU B 157
ILE B 166
ARG B 163
1.20A7.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 9
ALA C   1
GLY C  -1
ALA D 100
GLY C   2
ALA D  96
1.57A10.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5f22 NSP8
(SARSr-CoV)		4 / 6
LEU B 100
LEU B 103
ILE B 112
ARG B 101
1.77A15.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 6
LEU D 117
LEU D 157
ILE D 166
ARG D 163
1.14A6.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.71A14.02
None
None
None
None
DMS  A 403 ( 4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.46A14.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.58A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		5tl6 UBIQUITIN-LIKE
PROTEIN ISG15
(Homo
sapiens)		5 / 10
VAL A  86
SER A  93
SER A  83
VAL A 148
SER A 146
1.43A22.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		5x4r S PROTEIN
(MERS-CoV)		5 / 9
ALA A 138
SER A 137
GLY A 128
SER A 133
SER A 135
1.37A6.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 9
ALA A 875
GLY A 867
GLY A 871
ALA A 858
SER A 861
1.33A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
LEU C 538
LEU C 519
ASP C 312
ILE C 573
1.68A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 6
SER C  95
SER C 173
ALA C 250
SER C 248
1.36A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		5x5c S PROTEIN
(MERS-CoV)		5 / 9
ALA A 138
SER A 137
GLY A 128
SER A 133
SER A 135
1.37A2.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		5x5c S PROTEIN
(MERS-CoV)		4 / 6
SER A 133
SER A 135
ALA A 138
SER A 137
1.45A2.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		5x5c S PROTEIN
(MERS-CoV)		5 / 10
VAL C 846
ALA C1092
SER C1089
ALA C1096
SER C1095
1.13A2.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5x5c S PROTEIN
(MERS-CoV)		4 / 6
LEU C 506
LEU C 507
ASP C 509
ARG C 511
1.67A2.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		5x5f S PROTEIN
(MERS-CoV)		5 / 9
SER C1091
ALA C1096
SER C1095
SER C 845
SER C1089
1.54A2.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		5x5f S PROTEIN
(MERS-CoV)		4 / 6
ILE C1067
ARG C1069
LEU C1070
LEU C1058
1.38A2.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL A  97
SER A  95
VAL A  98
ALA A  91
ALA A 249
1.34A2.90
VAL  A  97 ( 0.6A)
SER  A  95 ( 0.0A)
VAL  A  98 ( 0.6A)
ALA  A  91 ( 0.0A)
ALA  A 249 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU B 264
LEU B  58
ILE B 272
ARG B  38
1.56A2.61
LEU  B 264 ( 0.6A)
LEU  B  58 ( 0.6A)
ILE  B 272 ( 0.7A)
ARG  B  38 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
LEU C 194
LEU C 222
ILE C 226
ARG A 342
1.63A2.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ALA C 590
SER C 591
GLY C 587
ALA C 658
SER C 659
1.59A1.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
GLY A  77
ALA A 250
SER A 248
ALA A  91
VAL A  97
1.48A1.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER C 964
ALA C 954
SER C 956
ALA C 971
1.37A1.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6acg ACE2
(Homo
sapiens)		5 / 9
SER D 545
ALA D 550
SER D 547
GLY D 319
SER D 411
1.46A5.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL A 711
ALA A1007
SER A1003
VAL A 763
ALA A1008
1.42A2.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
ALA A 875
GLY A 867
GLY A 871
ALA A 858
SER A 861
1.27A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
LEU A 571
LEU A 519
ASP A 564
ILE A 570
1.66A2.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
GLY A 246
ALA A 250
SER A 248
VAL A 140
ALA A 237
1.46A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6crz SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
ILE B 962
ARG B 977
LEU B 978
LEU B 966
1.40A2.58
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 6
SER B 686
ALA C 858
ALA C 864
SER C 861
1.37A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
VAL B 990
ALA B 997
ALA B 753
ALA B 748
SER B 750
1.43A2.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
ALA A 875
GLY A 867
GLY A 871
ALA A 858
SER A 861
1.29A1.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens;
SARSr-CoV)		4 / 6
LEU A 147
LEU C   9
ILE A 124
ARG A  97
1.54A9.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		4 / 6
SER D 937
ALA D 944
SER D 940
ALA F 942
1.38A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 9
SER B 937
ALA B 944
SER B 940
ALA A 942
VAL A1189
1.67A12.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 10
VAL C 952
VAL B 952
ALA B 956
ALA A1174
VAL A 952
1.37A12.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.72A6.67

None
None
None
None
DMS  A 403 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6lzg SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE B 358
ARG B 355
LEU B 513
ASP B 398
1.37A14.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6lzg ACE2
(Homo
sapiens)		5 / 9
SER A 545
SER A 411
ALA A 533
VAL A 318
SER A 547
1.53A4.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6lzg ACE2
(Homo
sapiens)		4 / 6
LEU A 116
LEU A 108
ILE A 119
ARG A 115
1.11A7.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6m0j ACE2
(Homo
sapiens)		4 / 6
LEU A 116
LEU A 108
ILE A 119
ARG A 115
1.15A6.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.72A7.02

None
None
None
None
DMS  A 401 (-3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.38A7.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 9
ALA C 247
SER C 323
GLY C 326
GLY C 246
ALA C 406
1.04A3.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
LEU A 482
LEU A 485
ILE A 132
ARG A  57
1.21A7.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 6
ILE C 132
LEU C  52
LEU C 482
ASP C 486
1.27A7.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m18 ACE2
(Homo
sapiens)		4 / 6
SER D 411
SER D 545
ALA D 550
SER D 547
1.39A2.75
None
NAG  D 910 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6m1d ACE2
(Homo
sapiens)		4 / 6
LEU B 359
TRP B 349
ILE B 358
ARG B 357
1.60A6.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ILE C  43
ARG C  40
LEU C  57
ASP C 187
1.67A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 301
ALA A 116
SER A 123
SER A 139
1.72A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.75A6.27

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 301
ALA B 116
SER B 123
SER B 139
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 147
SER C 121
ALA C 116
SER C 123
1.73A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 121
ALA D 116
SER D 123
SER D 147
1.60A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER C 121
ALA C 116
SER C 123
SER C 147
1.72A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER B 139
SER D 301
ALA B 116
SER B 123
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER D 147
SER D 121
ALA D 116
SER D 123
1.60A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
SER A 139
SER C 301
ALA A 116
SER A 123
1.71A6.71

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ILE C  43
ARG C  40
LEU C  87
LEU C  57
1.30A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
VAL D  36
VAL D  91
ALA D  94
VAL D  68
ALA D  70
1.70A6.27

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.45A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ILE A 466
ARG A 735
LEU A 470
ASP A 235
1.71A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
ALA A 383
VAL A 341
ALA A 379
SER A 343
VAL B 115
1.64A3.56

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
ASP A 303
ILE A 307
ARG A 305
1.66A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 120
LEU B  98
LEU B 117
ASP A 377
1.71A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
LEU A 308
LEU A 469
ILE A 307
ARG A 305
1.75A4.04

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m71 NSP12
(SARS-CoV-2)		5 / 10
ALA A 777
VAL A 704
ALA A 706
VAL A 785
SER A 784
1.68A3.56

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ILE A 244
ARG A 132
LEU A 131
LEU A 207
1.71A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 10
SER A 343
VAL B 115
ALA A 383
VAL A 341
ALA A 379
1.70A3.56

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		5 / 9
GLY A 584
ALA A 581
SER A 578
VAL A 587
ALA A 585
1.61A2.46

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.73A2.46

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m71 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 132
ARG A 392
LEU A 389
ASP A 390
1.30A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6m71 NSP12
(SARS-CoV-2)		4 / 6
ILE A 171
ARG A 173
LEU A 172
LEU A 146
1.36A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6m71 NSP12
(SARS-CoV-2)		5 / 10
VAL A 637
ALA A 634
ALA A 690
SER A 692
VAL A 476
1.43A3.56

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
GLY A 638
SER A 673
ALA A 658
SER A 659
ALA A 595
1.71A1.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 6
SER B 659
SER B 673
ALA B 639
ALA B 658
1.40A1.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
ALA C 875
GLY C 867
GLY C 871
ALA C 858
SER C 861
1.52A1.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6nur NSP12
(SARSr-CoV)		4 / 6
ILE A 171
ARG A 173
LEU A 172
LEU A 146
1.31A3.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6nur NSP12
(SARSr-CoV)		4 / 6
LEU A 302
ASP A 303
ILE A 307
ARG A 305
1.49A3.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6nur NSP12
(SARSr-CoV)		5 / 9
GLY A 584
ALA A 581
SER A 578
VAL A 587
ALA A 585
1.60A2.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU A 585
LEU A 533
ASP A 578
ILE A 584
1.31A3.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6vxs NSP3
(SARS-CoV-2)		4 / 6
LEU A 140
LEU A  12
ILE A 137
ARG A 141
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6vxs NSP3
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6vxs NSP3
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6vxs NSP3
(SARS-CoV-2)		5 / 10
VAL B  41
ALA B  39
ALA B  38
ALA B 112
VAL B  77
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
LEU C 242
LEU C 244
ILE C 101
ARG C 102
1.68A2.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
GLY A 652
SER A 691
ALA A 672
SER A 673
ALA A 609
1.71A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
SER B 937
SER B 940
ALA B 944
SER B 943
1.32A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
GLY C 652
SER C 691
ALA C 672
SER C 673
ALA C 609
1.69A2.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 298
LEU A 299
ASP A 302
ILE A 323
1.38A10.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 6
ILE C 358
ARG C 355
LEU C 513
ASP C 398
1.51A16.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 9
SER H 132
GLY H 133
ALA H 136
SER H 130
SER H 187
1.73A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 6
SER H 187
SER H 132
ALA H 136
SER H 130
1.68A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 6
ILE L  75
ARG L  61
LEU L  78
LEU L  47
1.52A15.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
VAL H 142
SER H 180
VAL H 150
VAL H 198
SER H 153
1.60A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
ALA H 168
SER H 177
VAL H 150
VAL H 142
SER H 180
1.79A14.91
None
GOL  L 301 (-3.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
VAL H 198
SER H 153
VAL H 142
SER H 179
VAL H 150
1.77A14.91
None
None
None
GOL  L 301 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
ALA H 168
SER H 177
VAL H 150
VAL H 142
SER H 179
1.77A14.91
None
GOL  L 301 (-3.1A)
None
None
GOL  L 301 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 9
SER H 187
SER H 132
GLY H 133
ALA H 136
SER H 130
1.71A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 9
SER H 132
GLY H 133
ALA H 136
SER H 130
SER H 187
1.72A7.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
VAL H 182
ALA H 137
VAL H 184
ALA H 136
SER H 186
1.60A14.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
SER H 180
VAL H 142
ALA H 168
SER H 177
VAL H 150
1.64A14.91
None
None
None
GOL  L 301 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 10
VAL H 198
VAL H 142
ALA H 168
SER H 177
VAL H 150
1.68A14.91
None
None
None
GOL  L 301 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w4b NSP9
(SARS-CoV-2)		5 / 9
GLY B 101
ALA A   9
ALA B 109
VAL A 103
SER A 106
1.41A11.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w4h NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.72A6.69
SAM  A7102 (-4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w4h NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.58A6.69
SAM  A7102 (-4.1A)
None
SAM  A7102 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
ALA A6905
VAL A6894
1.72A12.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.67A9.38
SAM  A7104 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
VAL A6902
ALA B4324
SER A6903
1.72A11.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6877
ALA A6870
SER A6896
SER A6907
1.45A12.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6905
ALA A6881
VAL A6876
ALA A6877
1.62A12.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA A6877
ALA A6870
SER A6896
ALA A6905
SER A6907
1.69A12.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.75A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.37A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6870
GLY A6871
ALA A6881
GLY A6879
ALA B4324
1.62A9.38
None
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.50A9.38
SAM  A7104 (-4.4A)
None
SAM  A7104 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
ALA A6870
SER A6896
ALA A6877
GLY A6871
SER A6903
1.75A9.38
None
None
None
SAM  A7104 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.55A11.25
None
None
AMP  A 201 ( 3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL B  41
ALA B  39
ALA B  38
ALA B 112
VAL B  77
1.55A11.25
None
None
MES  B 201 ( 3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL B  16
VAL B 151
ALA B 124
VAL B 144
SER B 139
1.75A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w6y NSP3
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.75A11.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
GLY D4322
ALA C6905
GLY D4347
ALA C6877
SER C6903
1.77A11.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 10
VAL C6902
ALA D4324
SER C6903
VAL C6876
ALA C6877
1.78A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
GLY C6871
ALA C6905
VAL C6902
ALA C6877
SER C6903
1.71A9.38
SAM  C7105 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.73A9.38
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
ARG C6884
LEU C6883
LEU C6892
ASP C6906
1.44A13.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6870
GLY C6871
ALA C6881
GLY C6879
ALA D4324
1.62A9.38
None
SAM  C7105 ( 4.2A)
None
SAM  C7105 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6881
GLY D4322
ALA C6905
GLY D4347
SER C6903
1.78A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ALA C6870
SER C6896
ALA C6877
SER C6903
VAL C6894
1.67A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ALA A6877
ALA A6870
SER A6896
ALA A6905
SER A6907
1.70A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
SER A6903
VAL A6894
1.66A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
ALA C6877
ALA C6870
SER C6896
ALA C6905
SER C6907
1.79A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.36A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.49A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
GLY B4347
ALA A6877
SER A6903
1.78A11.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6870
GLY A6871
ALA A6881
GLY A6879
ALA B4324
1.64A9.38
None
SAM  A7102 ( 4.2A)
None
SAM  A7102 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
GLY C6871
SER C6896
GLY C6869
ALA C6905
SER C6903
1.62A9.38
SAM  C7105 ( 4.2A)
None
SAM  C7105 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
VAL C6902
ALA C6905
ALA C6881
VAL C6876
ALA C6877
1.67A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.50A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.31A9.38
FMT  C7111 ( 4.8A)
None
None
FMT  C7111 ( 3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP16
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6905
ALA A6881
VAL A6876
ALA A6877
1.68A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w75 NSP10
NSP16
(SARS-CoV-2)		5 / 10
VAL A6902
ALA B4324
SER A6903
VAL A6876
ALA A6877
1.79A14.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.62A9.38
SAM  A7102 ( 4.2A)
None
SAM  A7102 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.68A9.38
SAM  A7102 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.69A9.38
None
FMT  C7111 ( 3.6A)
FMT  C7111 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6w75 NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.73A9.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
ALA C 246
SER C 245
ALA C 249
VAL C 303
SER C 262
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU C 120
LEU C 117
ILE C 123
ARG C 140
1.67A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU B 120
LEU B 117
ILE B 123
ARG B 140
1.70A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
ALA A 246
SER A 245
ALA A 249
VAL A 303
SER A 262
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU B 120
LEU B 117
ILE B 123
ARG B 140
1.77A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 6
LEU C 120
LEU C 117
ILE C 123
ARG C 140
1.72A9.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wcf NSP3
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.53A
None
MES  A 201 ( 4.7A)
MES  A 201 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wen NSP3
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wen NSP3
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6wey NSP3
(SARS-CoV-2)		4 / 6
LEU A 344
LEU A 216
ILE A 341
ARG A 345
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
GLY C 284
ALA C 273
GLY C 275
ALA D 313
SER D 312
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 313
SER F 312
GLY F 316
SER F 310
ALA E 308
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA C 313
SER C 312
GLY C 316
SER C 310
ALA D 308
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 313
SER D 312
GLY D 316
SER D 310
ALA C 308
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER E 310
ALA F 264
ALA E 311
SER E 312
1.61A
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER A 310
ALA B 264
ALA A 311
SER A 312
1.62A
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER B 310
ALA A 264
ALA B 311
SER B 312
1.61A
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 273
ALA A 313
GLY A 316
ALA A 311
SER A 310
1.80A
None
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE F 304
LEU F 353
LEU F 291
ASP F 288
1.44A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE D 304
LEU D 353
LEU D 291
ASP D 288
1.48A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE C 304
LEU C 353
LEU C 291
ASP C 288
1.43A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA C 264
GLY C 295
ALA D 313
GLY D 316
ALA D 311
SER D 310
1.73A
None
None
None
None
CL  C 401 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA F 273
ALA E 313
GLY E 316
ALA E 311
SER E 310
1.78A
None
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE B 304
LEU B 353
LEU B 291
ASP B 288
1.41A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 273
ALA B 313
GLY B 316
ALA B 311
SER B 310
1.77A
None
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE E 304
LEU E 353
LEU E 291
ASP E 288
1.42A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
GLY B 284
ALA B 273
GLY B 275
ALA A 313
SER A 312
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA E 313
SER E 312
GLY E 316
SER E 310
ALA F 308
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
GLY F 284
ALA F 273
GLY F 275
ALA E 313
SER E 312
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
GLY A 284
ALA A 273
GLY A 275
ALA B 313
SER B 312
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA B 313
SER B 312
GLY B 316
SER B 310
ALA A 308
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
ILE A 304
LEU A 353
LEU A 291
ASP A 288
1.44A14.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER D 310
ALA C 264
ALA D 311
SER D 312
1.61A
None
None
CL  C 401 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER F 310
ALA E 264
ALA F 311
SER F 312
1.65A
None
None
CL  E 401 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA F 264
GLY F 295
ALA E 313
GLY E 316
ALA E 311
SER E 310
1.72A
None
None
None
None
CL  F 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA A 264
GLY A 295
ALA B 313
GLY B 316
ALA B 311
SER B 310
1.72A
None
None
None
None
CL  A 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
GLY D 284
ALA D 273
GLY D 275
ALA C 313
SER C 312
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA D 264
GLY D 295
ALA C 313
GLY C 316
ALA C 311
SER C 310
1.73A
None
None
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 6
SER C 310
ALA D 264
ALA C 311
SER C 312
1.65A
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA D 273
ALA C 313
GLY C 316
ALA C 311
SER C 310
1.78A
None
None
None
CL  D 401 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA E 264
GLY E 295
ALA F 313
GLY F 316
ALA F 311
SER F 310
1.73A
None
None
None
None
CL  E 401 ( 4.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		6 / 9
ALA B 264
GLY B 295
ALA A 313
GLY A 316
ALA A 311
SER A 310
1.75A
None
None
None
None
CL  B 401 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 9
ALA A 313
SER A 312
GLY A 316
SER A 310
ALA B 308
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6877
ALA A6870
SER A6896
SER A6907
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER C6872
ALA D4324
SER D4325
ALA C6877
1.72A
SAH  C7102 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.68A
SAH  A7102 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
GLY B4347
ALA A6877
SER A6903
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6905
ALA A6881
VAL A6876
ALA A6877
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA A6877
ALA A6870
SER A6896
ALA A6905
SER A6907
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL C6902
ALA C6905
ALA C6881
VAL C6876
ALA C6877
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER A6872
ALA B4324
SER B4325
ALA A6877
1.77A
SAH  A7102 ( 4.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA C6870
SER C6896
ALA C6877
SER C6903
VAL C6894
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
GLY D4322
ALA C6905
GLY D4347
ALA C6877
SER C6903
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.64A
SAH  A7102 (-4.4A)
None
SAH  A7102 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6870
GLY A6871
ALA A6881
GLY A6879
ALA B4324
1.64A
None
SAH  A7102 (-4.4A)
None
SAH  A7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA C6870
SER C6896
ALA C6877
ALA C6905
VAL C6894
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY C6871
SER C6896
GLY C6869
ALA C6905
SER C6903
1.65A
SAH  C7102 (-4.4A)
None
SAH  C7102 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY C6871
ALA C6905
VAL C6902
ALA C6877
SER C6903
1.70A
SAH  C7102 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA C6997
SER C6998
ALA C6832
SER C7038
SER C6831
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA C6877
ALA C6870
SER C6896
ALA C6905
SER C6907
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wjt 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA C6870
GLY C6871
ALA C6881
GLY C6879
ALA D4324
1.63A
None
SAH  C7102 (-4.4A)
None
SAH  C7102 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ALA C6870
SER C6896
ALA C6877
SER C6903
VAL C6894
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6905
ALA A6881
VAL A6876
ALA A6877
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7038
ALA C6843
1.74A
None
FMT  C7111 ( 3.5A)
FMT  C7111 ( 4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
GLY C6871
SER C6896
GLY C6869
ALA C6905
SER C6903
1.65A
SFG  C7103 ( 4.1A)
None
SFG  C7103 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7038
ALA A6843
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ALA A6877
ALA A6870
SER A6896
ALA A6905
SER A6907
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7041
ALA A6832
SER A7039
ALA A6997
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.68A
SFG  A7103 ( 4.2A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
GLY C6871
ALA C6905
VAL C6902
ALA C6877
SER C6903
1.71A
SFG  C7103 ( 4.1A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.63A
SFG  A7103 ( 4.2A)
None
SFG  A7103 ( 3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A7038
SER A7041
ALA A6843
ALA A6832
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7038
SER C7041
ALA C6843
ALA C6832
1.30A
FMT  C7111 ( 4.9A)
None
None
FMT  C7111 ( 3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
ALA A6905
VAL A6894
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA A6870
GLY A6871
ALA A6881
GLY A6879
ALA B4324
1.63A
None
SFG  A7103 ( 4.2A)
None
SFG  A7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
VAL C6902
ALA C6905
ALA C6881
VAL C6876
ALA C6877
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
ALA C6870
GLY C6871
ALA C6881
GLY C6879
ALA D4324
1.62A
None
SFG  C7103 ( 4.1A)
None
SFG  C7103 ( 3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
GLY B4347
ALA A6877
SER A6903
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP10
NSP16
(SARS-CoV-2)		5 / 9
GLY D4322
ALA C6905
GLY D4347
ALA C6877
SER C6903
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wkq NSP16
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
SER A6903
VAL A6894
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C6896
ALA C6905
ALA C6877
SER C6903
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		5 / 9
ALA C6870
SER C6896
ALA C6877
GLY C6871
SER C6903
1.75A
None
None
None
SFG  C7103 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER C7041
ALA C6832
SER C7039
ALA C6997
1.68A
None
FMT  C7111 ( 3.5A)
FMT  C7111 ( 3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wkq NSP16
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ILE A 281
ARG A 258
LEU A 246
LEU A 255
1.73A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL B  85
ALA B  81
VAL B 102
SER B  98
ALA B  95
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 298
LEU A 299
ASP A 302
ILE A 323
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ILE B 281
ARG B 258
LEU B 246
LEU B 255
1.76A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ARG B 258
LEU B 255
LEU B 246
ASP B 283
1.59A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B 298
LEU B 299
ASP B 302
ILE B 323
1.50A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 266
LEU A 201
ILE A 281
ARG A 258
1.64A11.54
None
EDO  A 405 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
ARG A 258
LEU A 255
LEU A 246
ASP A 283
1.57A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B 298
LEU B 299
ASP B 302
ILE B 323
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 298
LEU A 299
ASP A 302
ILE A 323
1.42A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 10
VAL A  85
ALA A  81
VAL A 102
SER A  98
ALA A  95
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU B 298
LEU B 299
ASP B 302
ILE B 323
1.41A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 266
LEU A 201
ILE A 281
ARG A 258
1.65A11.54
None
EDO  A 405 (-4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 6
LEU A 298
LEU A 299
ASP A 302
ILE A 323
1.51A11.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.39A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
SER A 254
GLY A 258
SER A 267
VAL A 261
ALA A 260
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER D 128
SER D 139
ALA D 124
ALA D  38
1.37A
APR  D 201 (-4.3A)
None
None
APR  D 201 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.52A
None
None
APR  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
SER D 139
ALA D 124
ALA D  38
ALA D 129
SER D 128
1.56A
None
None
APR  D 201 (-3.2A)
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A 112
GLY A  78
ALA A  39
GLY A  97
SER A  80
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER D 139
ALA D  38
ALA D 129
SER D 128
1.41A
None
APR  D 201 (-3.2A)
APR  D 201 (-3.7A)
APR  D 201 (-4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL B  41
ALA B  39
ALA B  38
ALA B 112
VAL B  77
1.55A
None
None
APR  B 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL C  41
ALA C  39
ALA C  38
ALA C 112
VAL C  77
1.53A
None
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL D  41
ALA D  39
ALA D  38
ALA D 112
VAL D  77
1.54A
None
None
APR  D 201 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 6
SER A6896
ALA A6905
ALA A6877
SER A6903
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		4 / 6
SER A6872
ALA B4324
SER B4325
ALA A6877
1.79A
SO4  A7109 (-4.5A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
ALA A6870
GLY A6871
ALA A6881
GLY A6879
ALA B4324
1.65A
None
SAH  A7101 (-4.3A)
None
SAH  A7101 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
SER A6903
VAL A6894
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
ALA A6905
VAL A6902
ALA A6877
SER A6903
1.71A
SAH  A7101 (-4.3A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
ALA A6870
SER A6896
ALA A6877
ALA A6905
VAL A6894
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 10
VAL A6902
ALA B4324
SER A6903
VAL A6876
ALA A6877
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 9
GLY A6871
SER A6896
GLY A6869
ALA A6905
SER A6903
1.64A
SAH  A7101 (-4.3A)
None
SAH  A7101 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 10
VAL A6902
ALA A6905
ALA A6881
VAL A6876
ALA A6877
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
VAL A6902
ALA B4324
SER A6903
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6wq3 2'-O-METHYLTRANSFERA
SE
NSP10
(SARS-CoV-2)		5 / 9
GLY B4322
ALA A6905
GLY B4347
ALA A6877
SER A6903
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.45A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6y2g REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ILE B  43
ARG B  40
LEU B  87
LEU B  57
1.39A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
SER A 121
ALA A 116
SER A 123
GLY A 124
SER A 147
1.80A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
ALA A 116
SER A 123
GLY A 124
SER A 147
SER A 121
1.76A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.72A14.02
None
None
None
None
DMS  A 406 ( 4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.59A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.60A6.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.45A14.05
None
DMS  A 408 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU D 184
LEU D 180
ASP D 161
ILE D 185
1.79A14.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 6
LEU B 184
LEU B 180
ASP B 161
ILE B 185
1.78A14.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
LEU A 119
TRP A  12
ILE A 106
ARG A 109
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 6
LEU A 119
TRP A  12
ILE A 106
ARG A 109
1.75A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL B 186
ALA B 141
VAL B 188
ALA B 140
SER B 190
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 146
SER H 184
VAL H 154
VAL H 202
SER H 157
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 186
ALA H 141
VAL H 188
ALA H 140
SER H 190
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL B 202
VAL B 146
ALA B 172
SER B 181
VAL B 154
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
ILE C  81
ARG C  18
LEU C  79
LEU C  84
1.64A9.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
SER H 184
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yla LIGHT CHAIN
(Homo
sapiens)		4 / 6
ILE C  81
ARG C  67
LEU C  84
LEU C  53
1.51A9.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 202
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
SER B 184
VAL B 146
ALA B 172
SER B 181
VAL B 154
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL B 146
SER B 184
VAL B 154
VAL B 202
SER B 157
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE E 358
ARG E 355
LEU E 513
ASP E 398
1.35A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE A 358
ARG A 355
LEU A 513
ASP A 398
1.38A16.94
None
PG0  A 902 (-4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 186
ALA H 141
VAL H 188
ALA H 140
SER H 190
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 146
SER H 184
VAL H 154
VAL H 202
SER H 157
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
VAL H 202
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE E 358
ARG E 355
LEU E 513
ASP E 398
1.43A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 10
SER H 184
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.43A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
SER H 184
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL B 202
VAL B 146
ALA B 172
SER B 181
VAL B 154
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL B 146
SER B 184
VAL B 154
VAL B 202
SER B 157
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL B 186
ALA B 141
VAL B 188
ALA B 140
SER B 190
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE A 358
ARG A 355
LEU A 513
ASP A 398
1.34A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL H 202
VAL H 146
ALA H 172
SER H 181
VAL H 154
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 6
ILE E 358
ARG E 355
LEU E 513
ASP E 398
1.35A16.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL H 146
SER H 184
VAL H 154
VAL H 202
SER H 157
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
VAL H 186
ALA H 141
VAL H 188
ALA H 140
SER H 190
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 10
SER B 184
VAL B 146
ALA B 172
SER B 181
VAL B 154
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.45A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL D  41
ALA D  39
ALA D  38
ALA D 112
VAL D  77
1.55A
None
None
EDO  D 205 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU A 140
LEU A  12
ILE A 137
ARG A 141
1.65A13.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU D 140
LEU D  12
ILE D 137
ARG D 141
1.28A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  41
ALA B  39
ALA B  38
ALA B 112
VAL B  77
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  41
ALA C  39
ALA C  38
ALA C 112
VAL C  77
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   7
SER C   5
SER E 166
ALA B  70
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL E  41
ALA E  39
ALA E  38
ALA E 112
VAL E  77
1.52A
None
None
EPE  E 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.51A
None
None
EDO  A 202 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL E  16
VAL E 151
ALA E 124
VAL E 144
SER E 139
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU D 140
LEU D  12
ILE D 137
ARG D 141
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL E  41
ALA E  39
ALA E  38
ALA E 112
VAL E  77
1.55A
None
None
APR  E 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   5
SER E 166
ALA B  70
SER C   7
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  41
ALA C  39
ALA C  38
ALA C 112
VAL C  77
1.54A
None
None
APR  C 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL D  41
ALA D  39
ALA D  38
ALA D 112
VAL D  77
1.56A
None
None
APR  D 201 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.55A
None
None
APR  A 201 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU A 140
LEU A  12
ILE A 137
ARG A 141
1.74A13.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL D  16
VAL D 151
ALA D 124
VAL D 144
SER D 139
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
SER C   7
SER C   5
SER E 166
ALA B  70
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  16
VAL B 151
ALA B 124
VAL B 144
SER B 139
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU A 140
LEU A  12
ILE A 137
ARG A 141
1.68A13.87
None
None
EDO  A 206 (-4.6A)
EDO  A 206 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  41
ALA C  39
ALA C  38
ALA C 112
VAL C  77
1.54A
None
None
MES  C 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU A 140
LEU A  12
ILE A 137
ARG A 141
1.69A13.87
None
None
EDO  A 206 (-4.6A)
EDO  A 206 (-4.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU C 140
LEU C  12
ILE C 137
ARG C 141
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  16
VAL A 151
ALA A 124
VAL A 144
SER A 139
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL C  16
VAL C 151
ALA C 124
VAL C 144
SER C 139
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL A  41
ALA A  39
ALA A  38
ALA A 112
VAL A  77
1.53A
None
None
MES  A 201 (-3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  16
VAL B 151
ALA B 124
VAL B 144
SER B 139
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 6
LEU C 140
LEU C  12
ILE C 137
ARG C 141
1.61A13.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 10
VAL B  41
ALA B  39
ALA B  38
ALA B 112
VAL B  77
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE

(SARS-CoV-2;
synthetic
construct)		4 / 6
LEU C   4
ASP A 187
ILE A  43
ARG A  40
1.78A
PJE  C   5 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE

(SARS-CoV-2;
synthetic
construct)		4 / 6
ARG A  40
LEU A  57
LEU C   4
ASP A 187
1.47A9.02
None
None
PJE  C   5 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 147
SER A 121
ALA A 116
SER A 123
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7bqy MAIN PROTEASE

(SARS-CoV-2;
synthetic
construct)		5 / 10
VAL A 171
ALA A 194
ALA A 193
ALA C   2
ALA A 173
1.51A
None
None
None
02J  C   1 ( 3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
ILE A 244
ARG A 132
LEU A 131
LEU A 207
1.73A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 308
LEU A 469
ILE A 307
ARG A 305
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
ILE A 171
ARG A 173
LEU A 172
LEU A 146
1.36A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
ILE A 466
ARG A 735
LEU A 470
ASP A 235
1.79A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		7btf NSP8
(SARS-CoV-2)		4 / 6
LEU D  95
LEU D  98
ILE D 107
ARG D  96
1.55A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 132
ARG A 392
LEU A 389
ASP A 390
1.25A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		5 / 9
GLY A 584
ALA A 581
SER A 578
VAL A 587
ALA A 585
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_F_RIMF101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		5 / 9
ALA A 558
SER A 681
GLY A 683
GLY A 559
SER A 561
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7btf NSP12
(SARS-CoV-2)		5 / 10
ALA A 777
VAL A 704
ALA A 706
VAL A 785
SER A 784
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7btf NSP8
(SARS-CoV-2)		4 / 6
LEU B 184
LEU B 180
ASP B 161
ILE B 185
1.77A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
LEU A 648
ASP A 303
ARG A 305
1.78A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
ALA A 383
VAL A 341
ALA A 379
SER A 343
VAL B 115
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7btf NSP12
(SARS-CoV-2)		5 / 10
VAL A 535
ALA A 656
VAL A 354
ALA A 660
SER A 664
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		7btf NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
ASP A 303
ILE A 307
ARG A 305
1.55A4.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7btf NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 185
ARG A 392
LEU A 388
ASP A 390
1.75A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
SER A 343
VAL B 115
ALA A 383
VAL A 341
ALA A 379
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7btf NSP8
(SARS-CoV-2)		4 / 6
LEU D  95
LEU D  98
ILE D 107
ARG D  96
1.64A10.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		7btf NSP8
(SARS-CoV-2)		4 / 6
LEU D  95
LEU D  98
ILE D 107
ARG D  96
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
ILE A  43
ARG A  40
LEU A  87
LEU A  57
1.40A9.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
VAL A  36
VAL A  91
ALA A  94
VAL A  68
ALA A  70
1.70A
None
None
None
None
DMS  A 403 ( 4.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 6
SER A 121
ALA A 116
SER A 123
SER A 147
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
ASP A 303
ILE A 307
ARG A 305
1.53A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7bv1 NSP12
(SARS-CoV-2)		5 / 10
ALA A 777
VAL A 704
ALA A 706
VAL A 785
SER A 784
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ILE A 632
LEU A 351
LEU A 636
ASP A 304
1.79A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 241
LEU A 207
ILE A 244
ARG A 132
1.57A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ILE A 244
ARG A 132
LEU A 131
LEU A 207
1.74A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 9
SER A 681
GLY A 679
ALA A 690
SER A 635
VAL A 662
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7bv1 NSP8
(SARS-CoV-2)		4 / 6
LEU B 184
LEU B 180
ASP B 161
ILE B 185
1.80A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
LEU A 648
ASP A 303
ARG A 305
1.62A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ILE A 466
ARG A 735
LEU A 470
ASP A 235
1.63A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7bv1 NSP7
NSP8
(SARS-CoV-2)		4 / 6
SER C  54
ALA D 102
ALA D 152
SER D 151
1.14A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 132
ARG A 392
LEU A 389
ASP A 390
1.25A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
ILE A 171
ARG A 173
LEU A 172
LEU A 146
1.47A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv1 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 119
LEU B 122
LEU A 271
ASP A 269
1.77A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		7bv1 NSP12
(SARS-CoV-2)		4 / 6
LEU A 308
LEU A 469
ILE A 307
ARG A 305
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
LEU A 648
ASP A 303
ARG A 305
1.72A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 119
LEU B 122
LEU A 271
ASP A 269
1.63A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		7bv2 NSP8
(SARS-CoV-2)		4 / 6
LEU B 184
LEU B 180
ASP B 161
ILE B 185
1.77A10.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_C_RIMC101_0
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
SER A 709
ALA A 771
ALA A 777
SER A 778
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ILE A 171
ARG A 173
LEU A 172
LEU A 146
1.44A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_D_RIMD101_0
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 9
GLY A 584
ALA A 581
SER A 578
VAL A 587
ALA A 585
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LJC_A_RIMA1_1
(M2 PROTEIN, BM2
PROTEIN CHIMERA)		7bv2 NSP12
(SARS-CoV-2)		5 / 10
ALA A 777
VAL A 704
ALA A 706
VAL A 785
SER A 784
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 302
ASP A 303
ILE A 307
ARG A 305
1.54A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ILE A 244
ARG A 132
LEU A 131
LEU A 207
1.62A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
LEU A 308
LEU A 469
ILE A 307
ARG A 305
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv2 NSP12
(SARS-CoV-2)		4 / 6
ILE A 466
ARG A 735
LEU A 470
ASP A 235
1.64A3.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		4 / 6
ILE B 132
ARG A 392
LEU A 389
ASP A 390
1.22A10.14
None