Ligand ID: EZL


Drugbank ID:
DB00311
(Ethoxzolamide)


Indication:
For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.

Get human targets for EZL in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'EZL'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
VAL B 261
THR B 225
THR B 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		1q2w 3C-LIKE PROTEASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.41A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		1uj1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.37A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		1uk4 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.43A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.50A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.54A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2a5k 3C-LIKE PEPTIDASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 12
VAL A 198
VAL A 337
VAL A 333
LEU A 308
PRO A 318
1.18A25.27
None
GOL  A1010 (-3.8A)
None
None
GOL  A1010 ( 4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2acf REPLICASE
POLYPROTEIN 1AB
(SARS-COV
Tor2)		5 / 11
HIS C 227
GLU C 246
HIS C 276
LEU C 270
THR C 239
1.63A23.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2ajf ACE2
(Homo
sapiens)		5 / 11
GLU B 375
HIS B 374
ALA B 413
LEU B 370
THR B 371
1.77A18.78
 ZN  B 901 ( 3.7A)
ZN  B 901 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.52
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2alv REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.63A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.70A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2amd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.59A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 8
HIS D  14
VAL D  16
LEU D  53
ALA D  97
1.34A18.50
None
None
D10  C1099 ( 4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2cme HYPOTHETICAL PROTEIN
5
(SARSr-CoV)		4 / 8
HIS B  14
VAL B  16
LEU B  53
ALA B  97
1.36A19.70
None
None
D10  B1099 (-4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2d2d 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.36A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		4 / 8
VAL L 156
LEU L 133
THR L 132
ALA L 131
1.37A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 184
VAL H 182
LEU H 159
TRP H 154
1.20A18.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLN L 186
VAL L 156
LEU L 133
THR L 132
PRO L 121
1.33A22.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2dd8 IGG LIGHT CHAIN
(Homo
sapiens)		4 / 8
VAL L  47
VAL L  48
LEU L  73
THR L  74
1.35A20.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2duc REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
HIS B 172
GLU B 166
HIS B 163
VAL B 114
LEU B 141
1.44A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 11
HIS A  46
GLU A  65
HIS A  95
LEU A  89
THR A  58
1.68A22.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)
(SARSr-CoV)		5 / 12
VAL C  17
VAL C 156
VAL C 152
LEU C 127
PRO C 137
1.18A23.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.44A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
LEU C 200
THR C 201
ALA C 205
TRP B 107
1.34A22.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A   2
VAL A  74
LEU A  66
THR A  68
THR A  68
1.49A24.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
HIS A  70
LEU A  66
THR A  68
1.30A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.39A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 9
HIS A  70
HIS A  70
VAL A  74
LEU A  66
THR A  68
1.34A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 10
HIS A  70
HIS A  70
LEU A  66
THR A  68
ALA A  65
1.36A17.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		5 / 11
HIS A   2
ALA A  65
LEU A  66
THR A  68
THR A  68
1.36A17.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2gtb 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.75A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2jw8 NUCLEOCAPSID PROTEIN
(SARSr-CoV)		4 / 8
HIS B 335
LEU B 332
THR B 333
ALA A 337
1.41A17.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A18.80
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr)		5 / 10
VAL A  86
VAL A  62
LEU A  25
THR A  26
ALA A  33
1.37A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		4 / 8
VAL A  62
LEU A  25
THR A  26
ALA A  33
1.34A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.40A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2op9 REPLICASE
POLYPROTEIN 1AB
(PP1AB, ORF1AB)
3C-LIKE PROTEINASE
(3CL-PRO, 3CLP)
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.59A20.13
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
VAL A  96
LEU A  49
THR A  47
THR A  48
PRO A  50
1.57A23.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.60A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 11
HIS A 172
GLU A 166
HIS A 163
VAL A 114
ALA A   7
1.54A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.80A24.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.43A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.48A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2q6g POLYPEPTIDE CHAIN
REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 11
HIS B 163
HIS B 172
GLU B 166
ALA B  41
LEU D   5
1.74A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.61A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.36A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2qc2 3C-LIKE PROTEINASE
(-)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A21.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.34A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2qc2 3C-LIKE PROTEINASE
(-)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.41A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.75A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.79A23.72
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A20.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.62A20.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2qiq REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.50A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.43A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		2vj1 MAIN PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.55A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.46A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 164
VAL A 148
LEU A 177
THR A 175
1.37A22.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.80A21.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3aw1 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.59A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.63A26.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 9
VAL B 199
VAL B 121
LEU B 179
THR B 178
ALA B 170
1.57A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 199
LEU B 179
THR B 178
ALA B 170
PRO B 169
1.71A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3bgf F26G19 FAB
(Mus
musculus)		5 / 10
VAL B 121
VAL B 144
LEU B 154
THR B 153
THR B 155
1.64A26.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3bgf F26G19 FAB
(Mus
musculus)		4 / 8
VAL B 121
VAL B 144
LEU B 154
THR B 153
1.20A20.31
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3bgf F26G19 FAB
(Mus
musculus)		5 / 11
ALA H  78
THR H  58
THR H  57
PRO H  52
TRP H  47
1.67A22.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
GLU A 375
HIS A 374
ALA A 413
LEU A 370
THR A 371
1.68A18.89
 ZN  A 901 (-3.8A)
ZN  A 901 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS B 401
VAL B 404
LEU B 558
ALA B 384
1.35A16.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.49A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.53A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3e91 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3e9s NSP3
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.37A20.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.51A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.38A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.71A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.61A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3eaj 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU D 205
THR D 201
1.42A18.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.55A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.52A16.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.55A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 193
LEU A 167
PRO A 168
1.77A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.52A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 172
HIS A 163
VAL A 114
ALA A 139
1.34A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS B  41
HIS B 164
VAL B 186
LEU B 167
PRO B 168
1.79A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 194
LEU A 167
PRO A 168
1.71A22.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.58A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.62A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.35A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3f9h 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3fzd 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.39A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3i6k HLA, A-2
(Homo
sapiens)		4 / 8
HIS A 192
LEU A 201
THR A 200
ALA A 246
1.33A19.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS D 246
VAL D 247
LEU B 205
THR B 201
1.28A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS D 246
VAL D 247
LEU B 205
THR B 201
1.22A21.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.44A23.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.59A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.38A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3m3s 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.50A19.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.76A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.77A23.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.78A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.73A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
VAL A 186
LEU A 167
PRO A 168
1.69A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.48A23.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.37A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.34A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.58A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.56A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
GLU A 240
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.79A21.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3scj ACE2
(Homo
sapiens)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.42A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS A 241
VAL A 485
VAL A 487
LEU A 267
1.38A16.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL E 498
VAL E 420
LEU E 412
ALA E 406
PRO E 450
1.60A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.41A16.64
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
GLU B 375
HIS B 374
ALA B 413
LEU B 370
THR B 371
1.69A18.73
 ZN  B 901 (-3.6A)
ZN  B 901 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		3scl SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL F 498
VAL F 420
LEU F 412
ALA F 406
PRO F 450
1.63A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A21.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
HIS A  41
HIS A 164
ALA A 194
LEU A 167
PRO A 168
1.79A21.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.49A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		4mds 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A22.04
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 10
HIS A 172
HIS B 172
PHE B 128
LEU B 174
THR B 171
1.59A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.38A19.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		5 / 11
HIS A 172
HIS B 172
ALA B 177
LEU B 174
THR B 171
1.48A22.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
GLN B 244
VAL B 247
LEU B 262
THR B 225
THR B 226
1.72A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5b6o 3C-LIKE PROTEINASE
(SARSr-CoV)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.44A19.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.37A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.72A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.62A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.44A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.62A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.68A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.63A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
VAL A  36
VAL A  35
LEU A  32
THR A  98
1.76A20.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.65A16.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
VAL B 206
PHE B 242
VAL B 126
LEU B 174
THR B 171
1.36A20.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
HIS B  90
VAL B 160
ALA B  40
LEU B  37
THR B  55
1.75A21.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5wrg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL B 562
PHE B 529
VAL B 313
LEU B 538
THR B 539
1.44A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		4 / 8
VAL B  58
LEU C  31
THR C  35
ALA C  32
1.40A15.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
0.98A10.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
VAL C 810
VAL C 804
LEU C1078
THR C1076
THR C1077
1.29A11.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.34A11.33
VAL  B 581 ( 0.6A)
LEU  B 615 ( 0.6A)
THR  B 616 ( 0.8A)
ALA  B 618 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		5y3e REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
VAL A 206
PHE A 242
VAL A 126
LEU A 174
THR A 171
1.48A19.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
VAL B 596
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.46A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
HIS B  70
HIS B  33
VAL B  66
LEU B 209
1.25A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
VAL B 596
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.38A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
HIS C  70
HIS C  33
VAL C 254
VAL C  66
THR C  92
1.73A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
VAL A 596
VAL A 606
VAL A 581
LEU A 615
THR A 616
1.52A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
HIS C  70
HIS C  33
VAL C 254
VAL C  66
THR C  92
1.75A12.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
1.21A11.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ack ACE2
(Homo
sapiens)		5 / 11
HIS D 241
ALA D 443
LEU D 444
THR D 282
TRP D 275
1.59A18.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ack ACE2
(Homo
sapiens)		5 / 12
VAL D 581
VAL D 226
LEU D 520
THR D 517
THR D 519
1.39A19.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
VAL B 581
LEU B 615
THR B 616
ALA B 618
1.17A10.47
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
VAL A 581
LEU A 615
THR A 616
ALA A 618
1.08A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
VAL B 562
PHE B 529
VAL B 313
LEU B 538
THR B 539
1.50A12.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
HIS A1040
VAL A 933
VAL A 934
LEU A 930
ALA A1038
1.58A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6cs2 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 10
VAL B 498
VAL B 420
LEU B 412
ALA B 406
PRO B 450
1.55A10.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		6iex MHC CLASS I ANTIGEN
(Homo
sapiens)		5 / 10
HIS A 192
VAL A 189
LEU A 201
THR A 200
TRP A 274
1.65A21.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
HIS A 230
VAL A 181
LEU A 227
THR A 228
1.37A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr-CoV)		4 / 8
VAL A 356
LEU A 363
THR A 359
ALA A 362
1.18A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6jyt HELICASE
(SARSr)		5 / 10
HIS A 311
VAL A 314
LEU A 363
ALA A 362
PRO A 364
1.39A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6jyt HELICASE
(SARSr-CoV)		5 / 12
HIS A 311
VAL A 314
VAL A 305
LEU A 363
PRO A 364
1.25A18.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.75A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.62A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.54A21.45
None
ALC  D   2 ( 4.1A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.71A22.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.60A21.45
ALC  D   2 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m0j ACE2
(Homo
sapiens)		4 / 8
HIS A 345
VAL A 343
LEU A 359
THR A 347
1.29A16.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.54A21.17
None
N0A  D   2 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.65A22.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m17 ACE2
(Homo
sapiens)		4 / 8
HIS D 345
VAL D 343
LEU D 359
THR D 347
1.27A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m17 ACE2
(Homo
sapiens)		4 / 8
HIS B 345
VAL B 343
LEU B 359
THR B 347
1.05A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.76A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.78A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.77A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m1d ACE2
(Homo
sapiens)		5 / 10
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.76A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6m1d ACE2
(Homo
sapiens)		5 / 11
HIS D 378
HIS D 401
VAL D 404
LEU D 558
PRO D 321
1.77A15.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6m1d ACE2
(Homo
sapiens)		5 / 12
VAL D 226
VAL D 581
LEU D 520
THR D 517
THR D 519
1.37A15.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.45A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.53A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS C 246
VAL C 247
LEU C 205
THR C 201
1.44A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.57A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.49A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.61A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
GLU B 240
HIS B 246
VAL B 247
LEU B 205
THR B 201
1.66A19.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS B 164
HIS B  41
VAL B  42
LEU B  87
1.56A21.10
None
3WL  B 401 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.51A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS C 164
HIS C  41
VAL C  42
LEU C  87
1.55A21.10
None
3WL  C 401 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 10
GLN C 244
VAL C 247
LEU C 262
THR C 225
THR C 226
1.54A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS D 246
VAL D 247
LEU D 205
THR D 201
1.43A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.56A21.10
None
3WL  A 401 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS D 164
HIS D  41
VAL D  42
LEU D  87
1.52A21.10
None
3WL  D 401 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS C 246
VAL C 247
LEU C 205
THR C 201
1.49A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS D 246
VAL D 247
LEU D 205
THR D 201
1.48A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.46A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.40A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.44A21.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 128
LEU A 245
THR A 246
ALA A 250
1.61A13.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 182
LEU A 251
THR A 252
ALA A 253
1.34A13.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6m71 NSP12
(SARS-CoV-2)		5 / 12
VAL A 693
PHE A 480
VAL A 587
THR A 687
THR A 686
1.59A14.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m71 NSP8
(SARS-CoV-2)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.40A23.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6m71 NSP12
(SARS-CoV-2)		4 / 8
VAL A 128
LEU A 245
THR A 248
ALA A 250
1.62A13.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
HIS A 661
VAL A 642
VAL A 675
THR A 662
1.40A11.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
VAL C 581
LEU C 615
THR C 616
ALA C 618
1.28A11.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 198
VAL H 196
LEU H 173
TRP H 168
1.40A18.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 11
GLU L 200
VAL L 120
ALA L 117
LEU L 206
THR L 202
1.60A24.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6nb8 S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
HEAVY CHAIN
S230 ANTIGEN-BINDING
(FAB) FRAGMENT,
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS H 178
VAL L 168
ALA L 149
THR L 177
PRO L 118
1.63A23.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6nus NSP12
NSP8
(SARSr-CoV)		5 / 12
VAL A 330
VAL A 398
VAL B 115
THR B 123
THR B 124
1.44A13.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6nus NSP8
(SARSr-CoV)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.21A23.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN B 314
LEU C 861
THR C 734
THR C 859
PRO C 862
1.50A11.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
HIS A1058
VAL A 951
VAL A 952
LEU A 948
ALA A1056
1.72A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
HIS A1058
VAL A 951
VAL A 952
LEU A 948
ALA A1056
1.68A11.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6vw1 ACE2
(Homo
sapiens)		4 / 8
HIS A 345
VAL A 343
LEU A 359
THR A 347
1.28A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vw1 ACE2
(Homo
sapiens)		4 / 8
HIS A 401
VAL A 404
LEU A 558
ALA A 384
1.12A16.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6vxs NSP3
(SARS-CoV-2)		5 / 11
HIS B  45
GLU B  64
HIS B  94
LEU B  88
THR B  57
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  16
PHE B 168
VAL B 151
LEU B 126
PRO B 136
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A 144
PHE A 168
VAL A  16
LEU A 126
PRO A 136
1.77A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
PHE A 168
VAL A 151
LEU A 126
PRO A 136
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6vxs NSP3
(SARS-CoV-2)		5 / 11
HIS A  45
HIS A  94
ALA A  27
LEU A  88
THR A  57
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.38A
None
SO4  B 204 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.37A
None
SO4  A 203 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6vxs NSP3
(SARS-CoV-2)		5 / 12
GLN A 118
VAL A  34
VAL A  95
LEU A 122
THR A 149
1.72A
None
NHE  A 202 (-4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6vxs NSP3
(SARS-CoV-2)		5 / 11
HIS B  45
HIS B  94
ALA B  27
LEU B  88
THR B  57
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6vxs NSP3
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
HIS L 198
VAL L 146
VAL L 196
LEU L 136
1.78A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
HIS H 200
VAL H 198
LEU H 178
ALA H 168
1.63A17.99
None
None
GOL  L 301 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
VAL H 121
LEU H 124
ALA H 125
TRP H 154
1.52A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6w41 CR3022 FAB HEAVY
CHAIN
CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
HIS H 164
VAL L 163
ALA L 144
THR L 172
PRO L 113
1.66A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
GLU L 195
VAL L 115
ALA L 112
LEU L 201
THR L 197
1.56A19.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
VAL H 184
VAL H 182
LEU H 159
TRP H 154
1.24A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
HIS L 189
VAL L 150
PHE L 209
VAL L 132
LEU L 181
1.61A22.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
HIS A6867
VAL A6882
LEU A6848
ALA A6966
1.73A16.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.56A
X77  A 401 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.46A
None
X77  A 401 (-3.2A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.65A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  36
VAL A  35
LEU A  53
1.72A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.62A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLN A 118
VAL A  34
VAL A  95
LEU A 122
THR A 149
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  36
VAL B  35
LEU B  53
1.75A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  45
VAL B  95
VAL B  96
LEU B  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.44A
None
AMP  A 201 ( 4.4A)
None
AMP  A 201 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.52A
None
None
None
MES  B 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w6y NSP3
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w6y NSP3
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.65A23.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
HIS A6867
VAL A6882
LEU A6848
ALA A6966
1.71A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
VAL C7092
VAL C7094
LEU A6909
THR A6908
1.50A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.60A20.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6w75 NSP16
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.60A20.91
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w75 NSP16
(SARS-CoV-2)		4 / 8
HIS C6867
VAL C6882
LEU C6848
ALA C6966
1.71A17.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
HIS C 275
LEU C 117
THR C 119
ALA C 116
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
HIS B 275
LEU B 117
THR B 119
ALA B 116
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 275
LEU A 117
THR A 119
ALA A 116
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.49A
None
None
None
MES  A 201 ( 3.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wcf NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
THR A  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A 144
PHE A 168
VAL A  16
LEU A 126
PRO A 136
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6wcf NSP3
(SARS-CoV-2)		5 / 11
HIS A  45
GLU A  64
HIS A  94
LEU A  88
THR A  57
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wcf NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
PHE A 168
VAL A 151
LEU A 126
PRO A 136
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6wen NSP3
(SARS-CoV-2)		5 / 11
GLU A  64
HIS A  94
ALA A  27
LEU A  88
THR A  57
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wen NSP3
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wen NSP3
(SARS-CoV-2)		5 / 12
GLN A 118
VAL A  34
VAL A  95
LEU A 122
THR A 149
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		5 / 12
GLN A 322
VAL A 238
VAL A 299
LEU A 326
THR A 353
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
HIS A 249
VAL A 299
VAL A 300
LEU A 279
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
HIS A 290
VAL A 239
LEU A 257
THR A 261
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wey NSP3
(SARS-CoV-2)		4 / 8
HIS A 298
VAL A 239
LEU A 257
ALA A 254
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wey NSP3
(SARS-CoV-2)		5 / 12
VAL A 220
VAL A 359
VAL A 355
LEU A 330
PRO A 340
1.23A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL C7092
VAL C7094
LEU A6909
THR A6908
1.52A
FMT  C7107 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
VAL A7092
VAL A7094
LEU C6909
THR C6908
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		5 / 12
VAL C6882
PHE C7048
VAL C6842
THR C6993
PRO C6805
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL A7092
VAL A7094
LEU C6909
THR C6908
1.57A
 NA  A7102 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wkq NSP16
(SARS-CoV-2)		4 / 8
VAL C7092
VAL C7094
LEU A6909
THR A6908
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wkq NSP16
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.63A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
VAL A 148
LEU A 177
THR A 175
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.60A
None
U5G  A 401 (-3.3A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
VAL A 148
LEU A 177
THR A 175
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.62A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  45
VAL C  95
VAL C  96
LEU C  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS D  86
VAL D  35
LEU D  53
THR D  57
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
GLU B  64
HIS B  94
ALA B  27
LEU B  88
THR B  57
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
HIS B  45
VAL B  49
ALA B  27
LEU B  88
THR B  57
1.79A
None
APR  B 201 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.27A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
GLU C  64
HIS C  94
ALA C  27
LEU C  88
THR C  57
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.55A
None
None
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS D  45
VAL D  95
VAL D  96
LEU D  75
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN D 118
VAL D  34
VAL D  95
LEU D 122
THR D 149
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
GLU A  64
HIS A  94
ALA A  27
LEU A  88
THR A  57
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.53A
None
None
None
APR  B 201 (-3.3A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL D  16
VAL D 155
VAL D 151
LEU D 126
PRO D 136
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS B  45
VAL B  95
VAL B  96
LEU B  75
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS D  94
VAL D  35
LEU D  53
ALA D  50
1.50A
None
None
None
APR  D 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN C 118
VAL C  34
VAL C  95
LEU C 122
THR C 149
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS C  94
VAL C  35
LEU C  53
ALA C  50
1.52A
None
None
None
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
PRO C 136
1.34A
None
None
None
APR  C 201 (-4.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
VAL A6882
PHE A7048
VAL A6842
THR A6993
PRO A6805
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wqd NSP8
(SARS-CoV-2)		5 / 12
VAL B 130
VAL B 159
VAL B 131
THR B 137
THR B 141
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
HIS C  36
VAL C  11
THR B  84
ALA B  86
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6wqd NSP8
(SARS-CoV-2)		5 / 12
VAL D 130
VAL D 159
VAL D 131
THR D 137
THR D 141
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqd NSP7
NSP8
(SARS-CoV-2)		4 / 8
HIS A  36
VAL A  11
THR D  84
ALA D  86
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 10
GLN A  30
HIS A  50
VAL A  21
VAL A   7
THR A  34
1.77A20.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		4 / 8
HIS A 275
LEU A 117
THR A 119
ALA A 116
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		6y84 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.61A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A21.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.61A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.71A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
VAL A  36
VAL A  35
LEU A  32
THR A  98
1.77A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.41A20.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.67A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.64A17.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL D 130
VAL D 159
VAL D 131
THR D 137
THR D 141
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
VAL B 130
VAL B 159
VAL B 131
THR B 137
THR B 141
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
HIS A  36
VAL A  11
THR D  84
ALA D  86
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		4 / 8
HIS C  36
VAL C  11
THR B  84
ALA B  86
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
GLN C   6
VAL C 110
LEU C  79
THR C  20
THR C  78
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS H 168
VAL L 169
ALA L 150
THR L 178
PRO L 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 11
HIS B 168
VAL C 169
ALA C 150
THR C 178
PRO C 119
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
HIS L 195
VAL L 156
PHE L 215
VAL L 138
LEU L 187
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS B 204
VAL B 202
LEU B 182
ALA B 172
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL B 188
VAL B 186
LEU B 163
TRP B 158
1.25A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 11
GLU C 201
VAL C 121
ALA C 118
LEU C 207
THR C 203
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
VAL L 152
VAL L 202
LEU L 181
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		4 / 8
HIS L 204
VAL L 152
VAL L 202
LEU L 142
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.63A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 11
HIS H 168
VAL L 169
ALA L 150
THR L 178
PRO L 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
VAL B 188
VAL B 186
LEU B 163
TRP B 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
HIS L 195
VAL L 156
PHE L 215
VAL L 138
LEU L 187
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
HIS H 204
VAL H 202
LEU H 182
ALA H 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
HIS B 204
VAL B 202
LEU B 182
ALA B 172
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 11
HIS B 168
VAL C 169
ALA C 150
THR C 178
PRO C 119
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
VAL H 188
VAL H 186
LEU H 163
TRP H 158
1.26A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
HIS C 195
VAL C 156
PHE C 215
VAL C 138
LEU C 187
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A
PEG  A 405 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.47A
PEG  A 405 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.57A
PK8  A 401 (-3.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  86
VAL D  35
LEU D  53
THR D  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
PRO C 136
1.35A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  16
VAL E 155
VAL E 151
LEU E 126
PRO E 136
1.35A
None
EDO  E 205 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  94
VAL D  35
LEU D  53
ALA D  50
1.47A
None
None
None
EDO  D 206 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
HIS D  45
HIS D  94
ALA D  27
LEU D  88
THR D  57
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
VAL C  95
VAL C  96
LEU C  75
1.53A
None
None
None
EPE  C 202 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  45
VAL D  95
VAL D  96
LEU D  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
HIS C  45
HIS C  94
ALA C  27
LEU C  88
THR C  57
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  86
VAL E  35
LEU E  53
THR E  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  86
VAL D  35
LEU D  53
THR D  57
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  45
VAL E  95
VAL E  96
LEU E  75
1.54A
None
None
None
EPE  E 203 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL D  16
VAL D 155
VAL D 151
LEU D 126
PRO D 136
1.38A
None
EDO  D 208 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
VAL B  95
VAL B  96
LEU B  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  94
VAL C  35
LEU C  53
THR C  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  94
VAL E  35
LEU E  53
ALA E  50
1.50A
None
None
None
EPE  E 202 (-3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  94
VAL C  35
LEU C  53
ALA C  50
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
HIS A  45
HIS A  94
VAL A  35
ALA A  27
LEU A  88
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  94
VAL E  35
LEU E  53
ALA E  50
1.53A
None
None
None
APR  E 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  86
VAL E  35
LEU E  53
THR E  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL E  35
LEU E  88
THR E  57
ALA E  56
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS E  45
VAL E  95
VAL E  96
LEU E  75
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL E  16
VAL E 155
VAL E 151
LEU E 126
PRO E 136
1.36A
None
APR  E 201 ( 4.9A)
None
APR  E 201 (-4.7A)
EDO  B 202 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.36A
None
None
None
APR  B 201 (-4.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL A  35
LEU A  88
THR A  57
ALA A  56
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
VAL C  95
VAL C  96
LEU C  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.35A
None
APR  A 201 ( 4.8A)
None
APR  A 201 (-4.8A)
EDO  A 205 ( 4.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL B  35
LEU B  88
THR B  57
ALA B  56
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  45
VAL D  95
VAL D  96
LEU D  75
1.54A
None
None
None
EDO  D 202 (-4.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS D  94
VAL D  35
LEU D  53
ALA D  50
1.52A
None
None
None
APR  D 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.51A
None
None
None
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
HIS E  45
HIS E  94
VAL E  35
ALA E  27
LEU E  88
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.51A
None
None
None
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
PRO C 136
1.39A
None
APR  C 201 ( 4.9A)
None
APR  C 201 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  94
VAL C  35
LEU C  53
ALA C  50
1.49A
None
None
None
APR  C 201 (-3.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
VAL B  95
VAL B  96
LEU B  75
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL D  35
LEU D  88
THR D  57
ALA D  56
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
VAL C  35
LEU C  88
THR C  57
ALA C  56
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL A  16
VAL A 155
VAL A 151
LEU A 126
PRO A 136
1.34A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  45
VAL B  95
VAL B  96
LEU B  75
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL C  16
VAL C 155
VAL C 151
LEU C 126
PRO C 136
1.34A
None
EDO  C 206 ( 4.2A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  45
VAL A  95
VAL A  96
LEU A  75
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  94
VAL C  35
LEU C  53
ALA C  50
1.50A
None
None
None
MES  C 201 ( 3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
THR A  57
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  86
VAL B  35
LEU B  53
THR B  57
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  94
VAL A  35
LEU A  53
ALA A  50
1.52A
None
None
None
MES  A 201 ( 3.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS B  94
VAL B  35
LEU B  53
ALA B  50
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
VAL B  16
VAL B 155
VAL B 151
LEU B 126
PRO B 136
1.37A
None
EDO  B 202 (-4.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  86
VAL C  35
LEU C  53
THR C  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS A  86
VAL A  35
LEU A  53
THR A  57
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLN B 118
VAL B  34
VAL B  95
LEU B 122
THR B 149
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
HIS C  45
VAL C  95
VAL C  96
LEU C  75
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6zsl SARS-COV-2 HELICASE
NSP13
(SARS-CoV-2)		5 / 10
HIS A 311
VAL A 314
LEU A 363
ALA A 362
PRO A 364
1.31A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		6zsl SARS-COV-2 HELICASE
NSP13
(SARS-CoV-2)		5 / 10
HIS B 311
VAL B 314
LEU B 363
ALA B 362
PRO B 364
1.37A17.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A  41
HIS A 164
VAL A  42
LEU A  87
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
VAL A 261
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.71A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.42A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.72A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.75A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7btf NSP8
(SARS-CoV-2)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
VAL A 330
VAL A 398
VAL B 115
THR B 123
THR B 124
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
VAL A 128
LEU A 245
THR A 248
ALA A 250
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
VAL A 763
VAL A 764
LEU A 614
THR A 801
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7btf NSP12
(SARS-CoV-2)		5 / 12
VAL A 693
PHE A 480
VAL A 587
THR A 687
THR A 686
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7btf NSP12
(SARS-CoV-2)		4 / 8
VAL A 182
LEU A 251
THR A 252
ALA A 253
1.36A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.69A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.66A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 164
HIS A  41
VAL A  42
LEU A  87
1.52A
None
JRY  A 401 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 10
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.70A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
HIS A 246
VAL A 247
LEU A 205
THR A 201
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 9
GLN A 244
VAL A 247
LEU A 262
THR A 225
THR A 226
1.74A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
VAL A 693
PHE A 480
VAL A 587
THR A 687
THR A 686
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
VAL A 763
VAL A 764
LEU A 614
THR A 801
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
VAL A 182
LEU A 251
THR A 252
ALA A 253
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv1 NSP8
(SARS-CoV-2)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
VAL A 128
LEU A 245
THR A 248
ALA A 250
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv2 NSP8
(SARS-CoV-2)		4 / 8
VAL B 115
LEU B 103
THR B 124
ALA B 102
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
VAL A 693
PHE A 480
VAL A 587
THR A 687
THR A 686
1.66A
None
None
None
F86  P 102 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 182
LEU A 251
THR A 252
ALA A 253
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 12
VAL A 330
VAL A 398
VAL B 115
THR B 123
THR B 124
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
VAL A 128
LEU A 245
THR A 248
ALA A 250
1.60A
None