Ligand ID: 9F2


Drugbank ID:
DB01212
(Ceftriaxone)


Indication:
For the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph

Get human targets for 9F2 in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND '9F2'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER D 924
THR F 922
THR F 923
GLY D 928
ASP D 932
1.51A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER D 924
THR F 922
THR F 923
GLY D 928
ASP D 932
1.55A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER D 924
THR F 922
THR F 923
GLY D 928
ASP D 932
1.57A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 924
ASN A1168
THR A 922
THR A 921
GLU A 918
1.43A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER D 924
THR F 922
THR F 923
GLY D 928
ASP D 932
1.54A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 10
GLN E1161
THR D 922
ILE E1164
THR E 922
ASP E 932
1.64A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 10
GLN D1161
THR F 922
ILE D1164
THR D 922
ASP D 932
1.64A18.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B   1
ASN B 214
GLY B  -1
GLY B 215
ASP B 216
1.60A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
GLN A 110
ILE A 249
TYR A 209
THR A 257
ASP A 153
1.77A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		1wof 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B   1
ASN B 214
GLY B  -1
GLY B 215
ASP B 216
1.67A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER K  24
THR I  23
THR K  23
GLY K  28
ASP K  32
1.49A9.36
None
None
None
None
NA  K 205 (-2.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER K  24
ASN J  20
THR K  22
THR K  21
GLU K  18
1.50A9.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER E  24
ASN D  20
THR E  22
THR E  21
GLU E  18
1.52A9.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER I  24
THR G  22
THR G  23
GLY I  28
ASP I  32
1.48A9.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER I  24
THR G  22
THR G  23
GLY I  28
ASP I  32
1.45A9.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER I  24
THR G  22
THR G  23
GLY I  28
ASP I  32
1.49A9.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		1zv8 E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER K  24
THR I  23
THR K  23
GLY K  28
ASP K  32
1.48A9.36
None
None
None
None
NA  K 205 (-2.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		4 / 8
PHE F  97
GLN B  68
ILE B  73
GLY B  69
1.28A19.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		2ajf ACE2
(Homo
sapiens)		5 / 9
TYR B 207
THR B 517
ILE B 513
THR B 449
ASP B 509
1.52A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		2ajf ACE2
(Homo
sapiens)		5 / 9
TYR B 207
THR B 517
ILE B 513
THR B 449
ASP B 509
1.55A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR B 923
THR C 923
GLY C 928
ASP C 932
1.47A8.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR B 923
THR C 923
GLY C 928
ASP C 932
1.45A8.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR B 922
THR B 923
GLY C 928
ASP C 932
1.44A8.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR B 923
THR C 923
GLY C 928
ASP C 932
1.47A8.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		2beq SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR B 922
THR B 923
GLY C 928
ASP C 932
1.48A8.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.48A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.43A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.47A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.42A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER D 313
ARG C 294
GLY D 317
GLY C 288
ASP C 289
1.36A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.42A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER D 251
ASN D 270
ARG D 294
THR D 266
GLY D 296
1.52A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.45A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.44A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
SER H 313
ASN G 270
THR G 297
GLY G 296
THR G 266
1.47A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		2cjr NUCLEOCAPSID PROTEIN
(SARS-COV
TW1)		5 / 12
GLN C 295
SER D 313
GLY D 317
GLY C 288
ASP C 289
1.36A15.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		2dd8 IGG HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARSr-CoV)		5 / 12
ILE H  56
ASN H  58
THR S 487
GLY S 488
GLY H  50
1.52A20.98
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER B 115
SER B 104
ASN B 111
GLY B 288
ASP B 109
1.77A20.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		2fyg REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ILE A  99
THR A  56
THR A  51
GLY A  52
GLY A 127
1.55A22.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		2fyg REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
ILE A  99
THR A  56
THR A  51
GLY A  52
GLY A 127
1.46A22.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 12
SER S  15
SER O  15
ARG S  78
THR O  12
THR S  12
1.75A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 12
ILE D  99
THR D  56
THR D  51
GLY D  52
GLY D 127
1.40A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 12
ILE D  99
THR D  56
THR D  51
GLY D  52
GLY D 127
1.48A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 10
ARG I  78
PRO J  59
THR M  49
THR J  47
ASP E  29
1.72A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 9
ARG I  78
PRO J  59
THR M  49
THR J  47
ASP E  29
1.77A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		2ga6 ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 10
ARG I  78
PRO J  59
THR M  49
THR J  47
ASP E  29
1.57A22.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		2gdt NSP1 (EC 3.4.22.-)
P65 HOMOLOG
LEADER PROTEIN
(SARSr)		4 / 8
ARG A  88
GLN A  85
ILE A  84
GLY A  87
1.20A16.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		2gdt LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 12
SER A  89
THR A  92
GLY A  87
GLY A  83
ASP A  82
1.33A16.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2ghw ANTI-SCFV ANTIBODY,
80R
(Homo
sapiens)		5 / 12
SER D 139
SER D 154
THR D 152
THR D 234
GLY D 233
1.63A24.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 12
SER A  89
THR A  92
GLY A  87
GLY A  83
ASP A  82
1.60A16.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 12
SER A  89
THR A  92
GLY A  87
GLY A  83
ASP A  82
1.57A16.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		2hsx LEADER PROTEIN
P65 HOMOLOG
NSP1
(SARSr-CoV)		5 / 12
SER A  89
THR A  92
GLY A  87
GLY A  83
ASP A  82
1.61A16.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
SER C 118
ILE C  79
PRO C 111
THR C 120
GLY C 140
1.44A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
SER C 118
ILE C  79
PRO C 111
THR C 120
GLY C 140
1.45A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
ILE A 136
ASN A 142
THR A 196
THR A 169
GLY A 170
1.39A23.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		2pwx 3C-LIKE PROTEINASE
(SARS-COV
BJ01)		5 / 12
ILE A 136
ASN A 142
THR A 196
THR A 169
GLY A 170
1.37A23.37
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.48A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.50A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		2qcy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.45A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE A 280
ASN B 163
ARG B  61
THR A 285
GLY A 286
1.46A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 12
ILE A 280
ASN B 163
ARG B  61
THR A 285
GLY A 286
1.53A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 9
ILE E 295
PRO E 343
TYR E 342
THR E 340
ASP E 301
1.71A22.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2xyq PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A 283
ARG A  86
GLY A  92
ASP A 125
1.70A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.40A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		2xyr NSP10
(SARSr-CoV)		5 / 12
ILE B  99
SER B  67
THR B  56
GLY B  52
GLY B 127
1.35A22.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.49A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		2xyr PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.51A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		2xyv PUTATIVE 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ARG A 283
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.62A20.82
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
SARSr-CoV)		5 / 12
ASN H  60
ARG S 426
THR S 485
THR H  58
GLY H  49
1.57A21.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
SARSr-CoV)		5 / 12
ASN B  60
ARG A 426
THR A 485
THR B  58
GLY B  49
1.62A21.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
SARSr-CoV)		5 / 12
ASN B  60
ARG A 426
THR A 485
THR B  58
GLY B  49
1.60A21.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.40A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR F 475
THR B  27
PRO F 462
THR B  20
THR B  21
1.70A22.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR F 475
THR B  27
PRO F 462
THR B  20
THR B  21
1.71A22.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		3d0g ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR F 475
THR B  27
PRO F 462
THR B  20
THR B  21
1.67A22.71
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		3d0g ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.36A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR E 475
THR A  27
PRO E 462
THR A  20
THR A  21
1.64A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR E 475
THR A  27
PRO E 462
THR A  20
THR A  21
1.62A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.51A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 8
ASN B 432
PHE B 285
THR B 593
GLN B 598
ILE B 436
1.51A19.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3d0h ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR F 475
THR B  27
PRO F 462
THR B  20
THR B  21
1.65A22.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.53A17.28
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		3e9s NSP3
(SARSr-CoV)		5 / 12
SER A 115
SER A 104
ASN A 111
GLY A 288
ASP A 109
1.79A20.00
OCS  A 112 ( 4.7A)
None
OCS  A 112 ( 4.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 136
ASN A 142
THR A 196
THR A 169
GLY A 170
1.40A23.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE A 136
ASN A 142
THR A 196
THR A 169
GLY A 170
1.37A23.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.42A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.34A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		3f9f 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.38A23.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.52A23.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		3f9g 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.50A23.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE C 136
ASN C 133
THR C 175
ARG C 105
GLY C 183
1.53A22.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A   0
ASN A 214
THR A 280
GLY A  -1
GLY A 215
1.51A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A   0
ASN A 214
THR A 280
GLY A  -1
GLY A 215
1.51A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.40A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.43A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.44A22.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER A  86
THR B 199
THR B 201
GLY B 202
ASP A  77
1.60A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER B  86
ASN B 157
THR A 199
THR A 201
GLY A 202
1.38A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ILE A 223
ASN B 110
GLY B 164
GLY B 161
ASP B 109
1.46A20.12
None
None
GRM  B 801 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		3mj5 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		6 / 12
ILE A 223
ASN B 110
GLY B 164
GLY B 161
ASP B 109
GLU A 204
1.64A20.12
None
None
GRM  B 801 (-3.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		6 / 12
ASN A  64
ARG A 283
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.72A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.54A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.44A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		3r24 2'-O-METHYL
TRANSFERASE
(SARSr-CoV)		5 / 12
ASN A  64
ARG A  86
GLY A  92
THR A  93
ASP A 125
1.53A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.53A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 10
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.50A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.46A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 9
TYR B 207
THR B 517
ILE B 513
THR B 449
ASP B 509
1.52A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.45A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		3sci ACE2
(Homo
sapiens)		5 / 10
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.46A18.92
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR F 475
THR B  27
PRO F 462
THR B  20
THR B  21
1.65A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.52A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.54A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.61A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR E 475
THR A  27
PRO E 462
THR A  20
THR A  21
1.63A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
SPIKE GLYCOPROTEIN
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR E 475
THR A  27
PRO E 462
THR A  20
THR A  21
1.60A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 9
TYR A 207
THR A 517
ILE A 513
THR A 449
ASP A 509
1.52A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.52A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		3scl ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.57A18.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		3snb 3C-LIKE PROTEINASE
PEPTIDE ALDEHYDE
INHIBITOR AC-DSFDQ-H
(SARSr-CoV)		5 / 10
HIS A 164
ASP H   4
HIS A  41
THR A 135
HIS A 163
1.39A22.19
None
None
ECC  H   5 ( 4.9A)
None
ECC  H   5 ( 3.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		3vb3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
SER A   1
ASN A 214
THR B 135
GLY B 170
ASP A 216
1.66A22.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		4m0w REPLICASE
POLYPROTEIN 1A
UBIQUITIN
(Bos
taurus;
SARSr-CoV)		5 / 12
SER A 115
SER A 104
ASN A 111
GLY B  76
GLU A 264
1.73A20.41
 NA  A 402 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
ASN A 157
THR B 198
THR B 201
GLY B 202
ASP A  77
1.64A20.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.48A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.50A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
GLY A 211
1.49A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.49A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.47A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.50A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.51A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.50A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.47A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		4rna PAPAIN-LIKE PROTEASE
(Human
betacoronavirus
2c
EMC/2012)		5 / 12
SER A 247
SER A 167
THR A 308
GLY A 248
THR A 249
1.46A22.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		4twy 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
CYH A 300
SER A 301
ASN A 214
GLY A 302
THR A 304
1.64A22.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5c8s GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 8
THR D  21
GLN C  98
ILE C  55
GLY C  70
1.30A21.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5c8s NSP10
(SARSr-CoV)		5 / 12
PRO C 100
THR C  58
GLY C  50
THR C  51
GLY C  52
1.42A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
SER D 112
THR D 173
THR D 113
GLY D 114
GLY D 110
1.67A19.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5c8s NSP10
(SARSr-CoV)		5 / 12
ASN A  62
THR A  58
GLY A  50
THR A  51
GLY A  52
1.79A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
SER B 112
THR B 173
THR B 113
GLY B 114
GLY B 110
1.61A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 9
ARG D 213
ILE D 201
TYR D 235
THR D 219
ASP C  29
1.80A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		5 / 9
ARG D 213
ILE D 201
TYR D 235
THR D 219
ASP C  29
1.79A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		5c8u NSP10
(SARSr-CoV)		5 / 12
ILE C  99
THR C  56
THR C  51
GLY C  52
GLY C 127
1.26A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5c8u GUANINE-N7
METHYLTRANSFERASE
NSP10
(SARSr-CoV)		4 / 8
THR D  21
GLN C  98
ILE C  55
GLY C  70
0.95A21.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		5c8u NSP10
(SARSr-CoV)		5 / 12
ILE C  99
THR C  56
THR C  51
GLY C  52
GLY C 127
1.35A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER D 115
SER D 104
ASN D 111
GLY D 288
ASP D 109
1.73A20.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
ILE P  99
THR P  56
THR P  51
GLY P  52
GLY P 127
1.47A23.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		4 / 8
THR B  21
GLN N  98
ILE N  55
GLY N  70
1.18A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
PRO O 100
THR O  58
GLY O  50
THR O  51
GLY O  52
1.44A23.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
ASN M  62
THR M  58
GLY M  50
THR M  51
GLY M  52
1.72A23.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
SER D 112
THR D 173
THR D 113
GLY D 114
GLY D 110
1.68A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
GLN C 168
SER A 171
SER A 230
THR A 215
GLY A 176
1.21A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5r84 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ASN A 180
ARG A 105
ARG A  40
GLY A 179
ASP A 176
1.73A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.69A19.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 12
SER D 115
SER D 104
ASN D 111
GLY D 288
ASP D 109
1.79A20.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5x4s SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
PHE A 103
THR A  67
ILE A  87
GLY A 255
1.31A20.83
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 703
THR B 705
THR B1048
GLY B1028
GLY C 873
1.50A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 703
THR B 705
THR B1048
GLY B1028
GLY C 873
1.53A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 703
THR B 705
THR B1048
GLY B1028
GLY C 873
1.54A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 703
THR B 705
THR B1048
GLY B1028
GLY C 873
1.48A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 591
ILE B 674
THR B 588
GLY B 587
ASP B 649
1.52A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER B 703
THR B 705
THR B1048
GLY B1028
GLY C 873
1.47A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5x59 S PROTEIN
(MERS-CoV)		4 / 8
ASN A 981
THR A1121
ILE A 985
GLY B 963
1.24A13.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		5x59 S PROTEIN
(MERS-CoV)		5 / 12
SER A 966
ILE C1180
THR A 961
GLY A 963
GLY C 984
1.33A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
GLN C 769
THR B 705
THR B1048
GLY B1028
GLY C 871
1.25A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER A 248
SER A  95
PRO A 143
THR A 247
GLY A 246
1.30A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		4 / 8
PHE A 103
THR A  67
ILE A  87
GLY A 255
1.25A14.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE B 674
THR B 588
GLY B 587
THR B 585
GLY B 298
1.49A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER A 985
ARG A 977
THR A 988
GLY B 739
ASP B 976
1.75A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
SER A 248
SER A  95
PRO A 143
THR A 247
GLY A 246
1.32A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
ILE B 674
THR B 588
GLY B 587
THR B 585
GLY B 298
1.44A12.79
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		5x5c S PROTEIN
(MERS-CoV)		5 / 12
SER A 966
ILE C1180
THR A 961
GLY A 963
GLY C 984
1.45A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.30A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.34A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
CYH B 828
SER B 829
SER A 350
THR A  70
GLY B 825
1.33A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.29A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.33A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.35A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
CYH B 828
SER B 829
SER A 350
THR A  70
GLY B 825
1.29A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		6 / 12
GLN C 280
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.58A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.34A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
SER B 439
SER B 440
GLY B 578
THR B 579
GLY C  61
1.32A11.35
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.37A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.32A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.34A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
PHE A 103
THR A  67
ILE A  87
GLY A 255
1.17A15.11
PHE  A 103 ( 1.3A)
THR  A  67 ( 0.8A)
ILE  A  87 ( 0.6A)
GLY  A 255 ( 0.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.39A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.37A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.37A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
SER A 111
ASN A 230
GLY A 104
THR A 229
1.55A12.92
SER  A 105 ( 0.0A)
SER  A 111 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.41A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 105
ASN A 230
GLY A 104
THR A 229
ASP A  85
1.36A12.92
SER  A 105 ( 0.0A)
ASN  A 230 ( 0.6A)
GLY  A 104 ( 0.0A)
THR  A 229 ( 0.8A)
ASP  A  85 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
SER A 115
SER A 104
ASN A 111
GLY A 288
ASP A 109
1.77A19.82
 NA  A 405 (-2.9A)
NA  A 405 ( 3.9A)
None
NA  A 405 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 924
THR C 922
THR C 923
GLY B 928
ASP B 932
1.56A15.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 924
THR C 922
THR C 923
GLY B 928
ASP B 932
1.52A15.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 924
THR B 923
THR A 923
GLY A 928
ASP A 932
1.59A15.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 924
THR A 923
THR C 923
GLY C 928
ASP C 932
1.57A15.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6acc SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
GLN C 769
THR A 705
THR A1048
GLY A1028
GLY C 871
1.34A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.50A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
THR C 229
GLN C 112
ILE C 226
GLY C 104
1.16A15.11
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
THR C  55
PRO C  43
TYR C  42
THR C 215
ASP C  85
1.65A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6acd SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
THR C  55
PRO C  43
TYR C  42
THR C 215
ASP C  85
1.62A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6acg ACE2
(Homo
sapiens)		5 / 8
ASN D 432
PHE D 285
THR D 593
GLN D 598
ILE D 436
1.56A19.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
GLN C 301
ARG C 306
THR C 616
THR C 260
THR C 261
1.35A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
GLN A 301
ARG A 306
THR A 616
THR A 260
THR A 261
1.33A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.49A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.50A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE C 674
THR C 588
GLY C 587
THR C 585
GLY C 298
1.38A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER A 728
ASN B 526
GLY B 534
THR B 533
ASP B 312
1.63A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE C 674
THR C 588
GLY C 587
THR C 585
GLY C 298
1.45A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 674
THR A 588
GLY A 587
THR A 585
GLY A 298
1.39A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.48A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.49A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6acj SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 674
THR A 588
GLY A 587
THR A 585
GLY A 298
1.35A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE B 674
THR B 588
GLY B 587
THR B 585
GLY B 298
1.35A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 9
THR C  55
PRO C  43
TYR C  42
THR C 215
ASP C  85
1.62A13.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.49A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.50A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.51A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.47A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.51A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.50A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.48A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		6 / 12
ILE B 674
SER B 591
THR B 588
GLY B 587
THR B 585
GLY B 298
1.78A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
PHE C 629
THR A 848
ILE C 656
GLY C 655
1.29A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.49A12.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		4 / 8
ASN A 627
THR A 631
ILE A 637
GLY A 634
1.24A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER C 248
SER C  95
PRO C 143
THR C 247
GLY C 246
1.39A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.38A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.43A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.41A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER C 591
SER C 592
THR C 588
GLY C 587
THR C 585
1.40A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.35A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.38A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.40A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.37A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.42A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6crx SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
SER B 591
SER B 592
THR B 588
GLY B 587
THR B 585
1.38A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ASN B 189
ARG A 342
GLY B 225
GLY B 192
ASP B 191
1.62A12.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.50A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.47A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 10
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.49A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 10
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.46A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6cs2 ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.44A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6jyt HELICASE
(SARSr-CoV)		4 / 8
ARG A 490
GLN A 492
ILE A 493
GLY A 494
1.19A20.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
ASN B 116
GLY B 415
GLY B 118
ASP B 119
GLU B 418
1.79A18.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6jyt HELICASE
(SARSr-CoV)		5 / 12
GLN A 537
SER A 289
GLY A 287
GLY A 282
ASP A 401
1.40A18.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A22.89

None
ELL  D   3 (-3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6lzg ACE2
(Homo
sapiens)		5 / 8
ASN A 432
PHE A 285
THR A 593
GLN A 598
ILE A 436
1.64A19.40
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m0j SPIKE RECEPTOR
BINDING DOMAIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.24A19.55
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO E 499
ASN E 501
GLY E 504
GLY A 354
ASP A 355
1.38A21.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m0j ACE2
SPIKE RECEPTOR
BINDING DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO E 499
ASN E 501
GLY E 504
GLY A 354
ASP A 355
1.40A21.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A22.89

None
ELL  D   3 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.78A22.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO F 499
ASN F 501
GLY F 504
GLY F 502
ASP D 355
1.43A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m17 ACE2
RECEPTOR BINDING
DOMAIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO F 499
ASN F 501
GLY F 504
GLY F 502
ASP D 355
1.47A22.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m17 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
GLN C 274
GLY C 397
THR C 396
GLY C 395
ASP C 486
1.49A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m17 RECEPTOR BINDING
DOMAIN
(SARS-CoV-2)		4 / 8
ASN F 422
PHE F 400
ILE F 402
GLY F 404
1.31A20.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m18 ACE2
SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE B 759
ARG B 766
LYS A 221
THR A 218
GLY B 764
1.47A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
THR A 459
THR A 212
THR A 219
GLY A 220
GLU A 437
1.52A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
THR A 459
THR A 212
THR A 219
GLY A 220
GLU A 437
1.54A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m18 ACE2
SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE B 759
ARG B 766
LYS A 221
THR A 218
GLY B 764
1.49A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER C 291
GLY C  93
GLY C  99
ASP C 445
GLU C 501
1.45A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER C 291
GLY C  93
GLY C 102
ASP C 445
GLU C 501
1.70A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER A 291
SER A 290
GLY A  93
GLY A  99
ASP A 445
1.61A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.46A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.40A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		4 / 8
ASN C 515
PHE C 514
ILE C 518
GLY C 523
1.27A18.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER A 106
ILE A  92
ARG A  97
GLY A 102
GLY A  99
1.43A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 10
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.39A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER A 106
ILE A  92
ARG A  97
GLY A 102
GLY A  99
1.46A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE A 107
SER A 105
ARG A  95
GLY A  99
GLY A  93
1.41A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
SER A 291
SER A 290
GLY A  93
GLY A  99
ASP A 445
1.57A17.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.45A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 10
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.39A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6m1d ACE2
(Homo
sapiens)		5 / 9
TYR D 207
THR D 517
ILE D 513
THR D 449
ASP D 509
1.39A14.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.63A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A23.08
None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.72A23.08
None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.62A23.08

None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A23.08
None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.67A23.08

None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.65A23.08
None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 301
ASN B 214
THR B 304
GLY B 215
ASP B 216
1.65A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.69A23.08
None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.66A23.08
None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.68A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.62A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.60A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.60A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.56A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.59A23.08

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A23.08

None
3WL  A 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE D  43
ASN D  65
THR D  24
GLY D  23
THR D  21
1.54A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.61A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ASN B 180
ARG B 105
ARG B  40
GLY B 179
ASP B 176
1.66A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 147
SER B 144
PRO B 122
GLY B 146
GLY B  29
1.66A23.08
None
3WL  B 401 (-3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.71A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m2n 3CL PROTEASE
(SARS-CoV-2)		4 / 8
ASN D  65
PHE D  66
ARG D  60
ILE D  43
1.71A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER D 147
SER D 144
PRO D 122
GLY D 146
GLY D  29
1.70A23.08
None
3WL  D 401 ( 3.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER B 301
ASN B 214
THR B 304
GLY B 215
ASP B 216
1.71A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 301
ASN A 214
THR A 304
GLY A 215
ASP A 216
1.62A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER C 147
SER C 144
PRO C 122
GLY C 146
GLY C  29
1.64A23.08

None
3WL  C 401 (-3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.79A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.63A23.08

None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.68A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.53A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.76A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.75A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6m71 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.23A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		4 / 8
THR A 869
GLN A 877
ILE A 878
GLY A 867
1.22A14.99
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 674
THR A 588
GLY A 587
THR A 585
GLY A 298
1.50A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 674
SER A 591
THR A 588
GLY A 587
GLY A 298
1.44A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE C 674
SER C 591
THR C 588
GLY C 587
GLY C 298
1.46A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE C 674
SER C 591
THR C 588
GLY C 587
GLY C 298
1.39A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6nb6 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 674
THR A 588
GLY A 587
THR A 585
GLY A 298
1.51A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.49A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.55A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.52A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.54A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.50A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
SER C 703
THR C 705
THR C1048
GLY C1028
GLY B 873
1.55A12.89
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6nur NSP12
(SARSr-CoV)		5 / 12
SER A 561
SER A 564
THR A 567
ARG A 569
GLY A 683
1.75A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6nur NSP12
(SARSr-CoV)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.19A16.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6nur NSP12
NSP8
(SARSr-CoV)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.52A14.20
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.51A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 787
THR C 723
THR C1066
GLY C1046
GLY A 889
1.25A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE C 643
THR A 866
ILE C 670
GLY C 669
1.19A13.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.52A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.50A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ASN B 280
GLY B 283
THR B 284
ASP B 287
GLU B 224
1.77A12.07
NAG  B1316 ( 4.8A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.49A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER B 721
THR B 723
THR B1066
GLY B1046
GLY C 891
1.46A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.44A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.48A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6vw1 ACE2
(Homo
sapiens)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.44A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6vw1 ACE2
(Homo
sapiens)		5 / 10
GLN B 442
ILE B 446
TYR B 516
THR B 453
ASP B 367
1.50A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vw1 ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PRO E 499
ASN E 501
GLY E 504
GLY A 354
ASP A 355
1.44A23.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vw1 ACE2
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN A  96
PRO A 389
THR E 415
GLY E 416
ASP A  30
1.46A17.44
None
None
BMA  A 703 (-3.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.43A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.54A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 598
THR C 602
GLY C 601
ASP C 663
GLU C 309
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN A 787
THR C 723
THR C1066
GLY C1046
GLY A 889
1.39A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.53A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.79A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.80A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.51A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER C 721
THR C 723
THR C1066
GLY C1046
GLY A 891
1.49A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.44A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 692
SER A 605
THR A 602
GLY A 601
GLY A 311
1.47A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR A 768
ILE C 312
THR C 302
THR C 299
ASP C 663
1.78A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.73A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.46A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.73A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.74A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 692
THR C 602
GLY C 601
THR C 599
GLY C 311
1.38A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLN C 787
THR B 723
THR B1066
GLY B1046
GLY C 889
1.42A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.77A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.52A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 12
ILE C 692
SER C 605
THR C 602
GLY C 601
THR C 599
GLY C 311
1.55A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 326
THR C 323
GLY C 550
THR C 549
GLY C 548
1.47A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.50A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 9
THR B 768
ILE A 312
THR A 302
THR A 299
ASP A 663
1.77A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 692
SER B 605
THR B 602
GLY B 601
GLY B 311
1.56A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		6 / 12
ILE C 692
SER C 605
THR C 602
GLY C 601
THR C 599
GLY C 311
1.57A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
SER A 721
THR A 723
THR A1066
GLY A1046
GLY B 891
1.48A12.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ASN A 422
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.74A14.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.33A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.36A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.42A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6vyo NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B  94
LYS C  49
GLY C 116
THR C 115
GLY C 114
1.41A19.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		6w01 URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		4 / 4
CYH B 117
ILE A 116
PRO A 119
THR B 121
1.42A22.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		4 / 8
THR H   9
GLN H   6
ILE H  20
GLY H   8
1.28A19.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN H   1
SER H  96
SER C 383
GLY H  97
GLY H  94
1.60A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		4 / 8
PHE L  62
GLN L  79
ILE L  75
GLY L  16
1.46A17.44
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
SER L  63
ILE L  75
PRO L  59
THR L  72
GLY L  64
1.66A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
ASN C 422
PHE C 400
ILE C 402
GLY C 404
1.24A18.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
SER L  63
ILE L  75
PRO L  59
THR L  72
GLY L  64
1.61A21.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  87
THR H 110
THR H   9
GLY H   8
1.72A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		4 / 8
PHE C 400
ARG C 403
ILE C 402
GLY C 404
1.41A18.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  87
THR H 110
THR H   9
GLY H   8
1.76A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ILE H  98
SER H  96
THR H  31
GLY H  94
GLY H  35
1.58A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w41 CR3022 FAB HEAVY
CHAIN
(Homo
sapiens)		5 / 12
ILE H  98
SER H  96
THR H  31
GLY H  94
GLY H  35
1.68A19.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.51A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w4h NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.66A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w61 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.73A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.71A23.08
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.66A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.69A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A
None
X77  A 401 (-3.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.80A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.64A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.49A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.65A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.55A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.76A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.59A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.53A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		6 / 12
ASN C6862
ARG C6864
THR C6889
GLY C6890
THR C6891
ASP C6923
1.79A19.33
None
FMT  C7106 ( 2.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.69A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
ASN B4315
THR B4311
GLY B4303
THR B4304
GLY B4305
1.80A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.76A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.65A19.78
None
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.64A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.79A19.78
None
NA  C7101 ( 4.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6w75 NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ILE A  65
PRO A  57
THR A  35
GLY A  38
ASP A  60
1.53A19.48
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ILE E 304
GLY F 316
GLY E 287
ASP E 288
1.78A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.45A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 304
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.52A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN B 294
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 337
ARG A 262
THR B 334
GLY A 284
GLY B 316
1.76A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN E 294
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN F 294
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ILE B 304
GLY A 316
GLY B 287
ASP B 288
1.76A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.56A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.51A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ARG F 276
THR F 263
THR F 296
GLY F 295
1.68A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
PHE E 314
ARG E 319
ILE E 320
GLY E 321
1.78A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN A 294
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 304
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.71A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ARG A 276
THR A 263
THR A 296
GLY A 295
1.68A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.51A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN C 294
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 337
ARG A 262
THR B 334
GLY A 284
GLY B 316
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.47A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A 304
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.69A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ILE A 304
GLY B 316
GLY A 287
ASP A 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 337
ARG E 262
THR F 334
GLY E 284
GLY F 316
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.47A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN D 294
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE A 304
SER B 312
GLY B 316
GLY A 287
ASP A 288
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.52A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 304
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ILE C 304
GLY D 316
GLY C 287
ASP C 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.55A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.49A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 304
SER D 312
GLY D 316
GLY C 287
ASP C 288
1.67A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.54A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.49A
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 304
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 337
ARG F 262
THR E 334
GLY F 284
GLY E 316
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.49A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ARG B 276
THR B 271
GLN B 283
GLY B 275
1.64A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 337
ARG C 262
THR D 334
GLY C 284
GLY D 316
1.71A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 304
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.74A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.53A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B 312
ASN A 269
THR A 296
GLY A 295
THR A 265
1.52A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE B 304
SER A 312
GLY A 316
GLY B 287
ASP B 288
1.73A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.51A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 304
SER C 312
GLY C 316
GLY D 287
ASP D 288
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ILE F 304
GLY E 316
GLY F 287
ASP F 288
1.75A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER E 312
ASN F 269
THR F 296
GLY F 295
THR F 265
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
GLN E 283
PRO E 279
ASN E 285
THR F 332
GLY F 321
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.44A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ILE D 304
GLY C 316
GLY D 287
ASP D 288
1.79A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ARG C 276
THR C 263
THR C 296
GLY C 295
1.66A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 337
ARG E 262
THR F 334
GLY E 284
GLY F 316
1.73A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE D 337
ARG C 262
THR D 334
GLY C 284
GLY D 316
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER C 312
ASN D 269
THR D 296
GLY D 295
THR D 265
1.50A18.42
None
None
CL  D 401 ( 4.6A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 337
ARG F 262
THR E 334
GLY F 284
GLY E 316
1.80A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.50A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER F 312
ASN E 269
THR E 296
GLY E 295
THR E 265
1.44A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ASN B 345
GLN E 289
ILE E 292
GLY E 287
1.52A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE E 304
SER F 312
GLY F 316
GLY E 287
ASP E 288
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.53A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER A 312
ASN B 269
THR B 296
GLY B 295
THR B 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER D 312
ASN C 269
THR C 296
GLY C 295
THR C 265
1.56A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE F 304
SER E 312
GLY E 316
GLY F 287
ASP F 288
1.69A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wji NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 337
ARG D 262
THR C 334
GLY D 284
GLY C 316
1.79A18.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.62A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.61A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.67A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
ASN D4315
THR D4311
GLY D4303
THR D4304
GLY D4305
1.80A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.76A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.68A
None
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.58A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.61A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.79A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.76A20.97
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wjt NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.65A
None
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.71A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
SER B  78
ILE B 157
PRO B  73
ARG A 107
THR A  57
1.66A
None
None
None
MES  B 201 (-4.8A)
MES  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.72A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.72A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		4 / 8
ASN B  77
PHE A 171
ARG A 107
GLN A  58
1.46A17.30
None
None
MES  B 201 (-4.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.67A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.74A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
LYS D  49
THR D 148
GLY D 116
THR D 115
GLY D 114
1.68A19.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.66A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		6 / 12
SER D4320
PRO D4353
THR D4311
GLY D4303
THR D4304
GLY D4305
1.64A
None
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		6 / 12
ASN C6862
ARG C6864
THR C6889
GLY C6890
THR C6891
ASP C6923
1.79A20.97
None
FMT  C7106 ( 2.7A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.66A
None
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.61A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.80A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
ILE B4352
THR B4309
THR B4304
GLY B4305
GLY B4380
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
PRO D4353
THR D4300
THR D4302
GLY D4303
GLY D4305
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.77A19.78
None
NA  A7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.78A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN C6862
THR C6889
GLY C6890
THR C6891
ASP C6923
1.57A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.77A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
SER D4320
THR D4311
GLY D4303
THR D4304
GLY D4305
1.75A19.78
None
NA  C7101 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ASN A6862
THR A6889
GLY A6890
THR A6891
ASP A6923
1.77A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER C7074
ILE C7069
SER C7071
GLY C7076
GLY C6962
1.60A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
SER A7071
GLY A7076
GLY A6962
1.63A20.97
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wkq NSP10
(SARS-CoV-2)		5 / 12
PRO B4353
ASN B4315
GLY B4303
THR B4304
GLY B4305
1.78A19.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
SER A 274
PRO A 271
THR A 196
THR A 275
ASP A  88
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
SER B 274
PRO B 271
THR B 196
THR B 275
ASP B  88
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.70A23.08
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.65A
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.72A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A
None
U5G  A 401 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		4 / 8
ASN C 101
PHE C 132
ILE C 131
GLY C  48
1.77A19.76
None
APR  C 201 (-3.5A)
APR  C 201 (-3.9A)
APR  C 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
PRO B4353
ASN B4315
GLY B4303
THR B4304
GLY B4305
1.76A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A7074
ILE A7069
ARG A7053
GLY A7076
GLY A6962
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		4 / 8
ASN A6827
THR A6993
ILE A7035
GLY A6806
1.71A19.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.79A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.72A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7005
SER A6964
ARG A7053
GLY A7076
THR A6856
1.51A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		5 / 12
SER B4320
THR B4311
GLY B4303
THR B4304
GLY B4305
1.77A19.78
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wq3 NSP10
(SARS-CoV-2)		6 / 12
SER B4320
PRO B4353
THR B4311
GLY B4303
THR B4304
GLY B4305
1.67A
None
None
None
SO4  B4403 (-3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A7088
SER A7090
THR A6915
GLY A6911
ASP A6895
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
SER A6964
ARG A7014
ARG A7053
GLY A7076
THR A6856
1.74A
None
None
None
None
8NK  A7103 (-2.9A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.63A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.68A19.17
None
DMS  A 405 ( 3.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
PRO A 111
ARG A 109
GLY A  76
THR A  75
GLY A 107
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A  35
THR A 125
GLN A 120
ILE A  34
1.71A17.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.55A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yi3 NUCLEOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 106
THR A   9
GLY A  76
THR A  75
GLY A  74
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.61A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ILE H  50
PRO L 101
GLY E 381
THR H 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.70A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A 422
PHE A 400
ILE A 402
GLY A 404
1.17A20.87
None
None
None
DMS  A 903 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.72A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.64A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.67A
None
None
None
None
MLI  E 908 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.51A20.87
None
None
None
DMS  E 902 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.60A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.18A20.87
None
None
None
DMS  E 902 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
THR B   9
GLN B   6
ILE B  20
GLY B   8
1.29A19.54
MLI  B 304 (-4.0A)
None
None
MLI  H 305 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 10
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.65A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE B  20
THR B  91
THR B 116
THR B   9
GLY B   8
1.71A20.94
None
None
None
MLI  B 304 (-4.0A)
MLI  H 305 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER C  69
ILE C  81
PRO C  65
THR C  78
GLY C  70
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.65A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 10
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.73A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  91
THR H 116
THR H   9
GLY H   8
1.71A20.94
None
None
None
None
MLI  B 304 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER C  69
ILE C  81
PRO C  65
THR C  78
GLY C  70
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE A 392
THR B 104
ILE C  34
GLY A 381
1.79A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE E 392
THR H 104
ILE L  34
GLY E 381
1.78A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla HEAVY CHAIN
(Homo
sapiens)		4 / 8
THR H   9
GLN H   6
ILE H  20
GLY H   8
1.27A19.54
None
None
None
MLI  B 304 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.45A20.87
None
None
None
DMS  A 903 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.69A20.94
None
None
None
None
MLI  E 908 ( 4.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE B  20
THR B  91
THR B 116
THR B   9
GLY B   8
1.75A
None
None
None
MLI  B 304 (-4.0A)
MLI  H 305 (-3.2A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yla SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE A 472
PRO A 491
ARG A 454
THR A 478
GLY A 476
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
GLN B   1
SER C  62
THR E 385
GLY C  63
THR H   0
1.77A
None
MLI  B 303 ( 3.9A)
None
None
MLI  B 303 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  91
THR H 116
THR H   9
GLY H   8
1.74A
None
None
None
None
MLI  B 304 ( 4.0A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.50A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.52A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ym0 HEAVY CHAIN
(Homo
sapiens)		4 / 8
THR H   9
GLN H   6
ILE H  20
GLY H   8
1.34A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.53A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6ym0 LIGHT CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.72A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.68A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.50A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ym0 SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 8
ASN E 422
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.57A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.70A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.52A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6ym0 HEAVY CHAIN
LIGHT CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.53A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.61A
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
P6N  A 502 (-3.3A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE E 392
THR H 104
ILE L  34
GLY E 381
1.78A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
THR B   9
GLN B   6
ILE B  20
GLY B   8
1.27A19.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.72A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN A 422
PHE A 400
ILE A 402
GLY A 404
1.19A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.59A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.69A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE E 400
ARG E 403
ILE E 402
GLY E 404
1.51A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 10
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE B  20
THR B  91
THR B 116
THR B   9
GLY B   8
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
SER L  69
ILE L  81
PRO L  65
THR L  78
GLY L  70
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.60A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 10
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.78A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
SER C  69
ILE C  81
PRO C  65
THR C  78
GLY C  70
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE B  20
THR B  91
THR B 116
THR B   9
GLY B   8
1.71A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
(Homo
sapiens)		4 / 8
THR H   9
GLN H   6
ILE H  20
GLY H   8
1.27A19.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  91
THR H 116
THR H   9
GLY H   8
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.69A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 10
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.73A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 10
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.73A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ILE B  50
PRO C 101
GLY A 381
THR B 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ARG B  59
THR C 100
GLY A 413
GLU B  57
1.69A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ILE H  50
PRO L 101
GLY E 381
THR H 104
1.78A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 10
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.78A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
PHE A 400
ARG A 403
ILE A 402
GLY A 404
1.51A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.70A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor SPIKE GLYCOPROTEIN
(SARS-CoV-2)		4 / 8
ASN E 422
PHE E 400
ILE E 402
GLY E 404
1.18A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER B 103
ARG B  59
THR C 100
GLY A 413
GLU B  57
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR L 102
ILE H 102
TYR H  32
THR E 385
ASP E 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 9
TYR C 102
ILE B 102
TYR B  32
THR A 385
ASP A 428
1.62A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR C 102
THR B 104
ILE B  50
TYR B  32
THR B  31
1.70A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		4 / 8
PHE A 392
THR B 104
ILE C  34
GLY A 381
1.78A21.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
(Homo
sapiens)		5 / 9
TYR L 102
THR H 104
ILE H  50
TYR H  32
THR H  31
1.72A20.74
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
IGG L CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
SER H 103
ARG H  59
THR L 100
GLY E 413
GLU H  57
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
SER C  69
ILE C  81
PRO C  65
THR C  78
GLY C  70
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE H  20
THR H  91
THR H 116
THR H   9
GLY H   8
1.69A20.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A23.08
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.64A
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.62A
None
DMS  A 403 ( 2.9A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A 101
PHE A 132
ILE A 131
GLY A  48
1.77A20.60
None
EDO  A 202 (-3.9A)
EDO  A 202 (-4.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN A 101
PHE A 132
ILE A 131
GLY A  48
1.74A20.60
None
APR  A 201 (-3.7A)
APR  A 201 (-3.1A)
APR  A 201 (-3.4A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		4 / 8
ASN B 101
PHE B 132
ILE B 131
GLY B  48
1.75A20.60
None
APR  B 201 (-3.5A)
APR  B 201 (-3.2A)
APR  B 201 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.67A
None
PJE  C   5 ( 4.1A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.74A23.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ILE A  43
ASN A  65
THR A  24
GLY A  23
THR A  21
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bqy MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.78A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A  27
PRO A  21
ARG A  74
THR A  26
GLY A  25
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.76A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.78A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.75A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.74A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.77A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
SER A 681
THR A 686
THR A 687
THR A 680
GLY A 679
1.75A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7btf NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.21A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.58A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
SER A 147
SER A 144
PRO A 122
GLY A 146
GLY A  29
1.66A
None
DMS  A 402 ( 3.6A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		4 / 8
ASN A  65
PHE A  66
ARG A  60
ILE A  43
1.78A22.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
SER A 343
ILE B 120
THR A 344
GLY A 345
GLY A 327
1.58A14.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv1 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.17A16.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
SER A 501
ILE A 562
ASN A 507
GLY A 559
GLU A 665
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ILE A 562
ARG A 654
THR A 531
THR A 567
GLU A 658
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 480
THR A 591
ILE A 579
GLY A 590
1.30A16.22
None
None
None
A  T  13 ( 3.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
ASN A 414
PHE A 415
ARG A 858
GLY A 841
1.79A16.22
None
None
U  P  17 ( 3.2A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		7bv2 NSP12
(SARS-CoV-2)		4 / 8
PHE A 812
ARG A 583
THR A 582
GLY A 584
1.64A16.22
None