Ligand ID: OQR


Drugbank ID:
DB01096
(Oxamniquine)


Indication:
For treatment of Schistosomiasis caused by Schistosoma mansoni

Get human targets for OQR in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'OQR'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 9
LEU A  87
VAL A  77
ILE A  78
ASP A  34
SER A  81
1.78A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 12
ILE B1286
GLY B1283
THR A 280
MET B1276
THR B1280
1.41A21.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 10
MET G  72
ILE H 124
VAL D  27
LEU D  25
SER D  66
1.73A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 10
LEU X  14
VAL U  21
ASP U  29
PHE U  16
SER X  11
1.80A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		2g9t ORF1A POLYPROTEIN
(SARSr-CoV)		5 / 9
PRO U  23
LEU X  14
ILE X  81
PHE Q  19
SER U  15
1.69A17.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2h85 PUTATIVE ORF1AB
POLYPROTEIN
(SARSr-CoV)		5 / 10
PRO A  65
VAL A 162
LEU A 167
SER A 171
GLU A 170
1.76A21.49
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2liz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
ILE A 281
LEU A 272
VAL A 204
LEU A 205
PHE A 219
1.64A20.00
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
MET A 218
ILE A 222
VAL A 236
LEU A 250
GLU A 210
1.56A22.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		2rhb URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARSr-CoV)		5 / 10
PRO D  65
VAL D 162
LEU D 167
SER D 171
GLU D 170
1.71A22.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		3avz 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
ILE A 281
LEU A 205
LEU A 253
ASP A 216
PHE A 219
1.76A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		3aw0 3C-LIKE PROTEINASE
PEPTIDE
ACE-SER-ALA-VAL-LEU-
HIS-H
(SARSr-CoV)		5 / 9
PRO A  39
LEU A  27
LEU B   5
PHE A 140
SER A 144
1.75A20.26
None
None
HSV  B   6 ( 4.4A)
None
HSV  B   6 (-3.5A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		3d0i ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE A 407
VAL A 574
GLY A 551
MET A 557
LEU A 558
0.76A16.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		3e9s NSP3
(SARSr-CoV)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.46A21.30
None
None
TTT  A 317 (-3.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		3iwm 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 10
ILE A  78
LEU A  75
VAL A  36
LEU A  32
SER A  94
1.79A20.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		3scj ACE2
(Homo
sapiens)		5 / 12
ILE A 407
VAL A 574
GLY A 551
MET A 557
LEU A 558
0.69A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
ILE A 407
VAL A 574
GLY A 551
MET A 557
LEU A 558
0.66A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		4ovz PAPAIN-LIKE
PROTEINASE
(SARS-COV
Urbani)		5 / 12
PHE A 305
LEU A 102
GLY A 164
MET A 170
THR A 169
1.47A21.43
None
None
DMS  A 903 (-3.0A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PHE D 445
ILE D 474
PHE D 523
THR D 522
MET D 315
1.36A19.96
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5c8t GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 12
PHE D 445
ILE D 474
PHE D 523
THR D 522
MET D 315
1.36A19.93
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
MET A 170
LEU A 121
LEU A 102
ILE A 277
PHE A 305
1.72A18.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 9
PRO A 412
LEU A 411
LEU A 406
ASP A 402
PHE A 401
1.79A18.45
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 12
PHE C 445
ILE C 474
PHE C 523
THR C 522
MET C 315
1.33A19.59
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		5tl6 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 9
MET B 170
LEU B 121
LEU B 102
ILE B 277
PHE B 305
1.68A19.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5x5b SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 12
PHE B 782
VAL B1047
GLY B 867
PHE B1034
MET B 884
1.49A12.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5x5f S PROTEIN
(MERS-CoV)		5 / 12
HIS A 670
LEU A 697
GLY A 712
PHE A 674
LEU A 759
1.51A11.70
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE C 787
LEU C 859
VAL C1015
THR C 863
THR C 705
1.45A12.16
ILE  C 787 ( 0.7A)
LEU  C 859 ( 0.6A)
VAL  C1015 ( 0.6A)
THR  C 863 ( 0.8A)
THR  C 705 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 10
PRO A1035
ILE A 852
LEU A 859
LEU A 788
ASP A 850
1.65A12.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ILE A 584
VAL A 581
GLY A 653
THR A 302
THR A 631
1.37A12.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
PHE A 782
VAL A1047
GLY A 867
PHE A1034
MET A 884
1.48A12.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 9
PRO B 513
LEU B 374
LEU B 322
ILE B 345
PHE B 329
1.52A11.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6cs1 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
ILE B 787
LEU B 859
VAL B1015
THR B 863
THR B 705
1.31A12.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6jyt HELICASE
(SARSr-CoV)		5 / 10
ILE A  35
LEU A  25
VAL A  42
LEU A  43
ASP A  59
1.69A17.08
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6lxt SPIKE PROTEIN S2
(SARS-CoV-2)		5 / 12
ILE F 934
LEU E1186
GLY D 932
THR F 941
LEU D1193
1.49A21.07
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6lzg ACE2
(Homo
sapiens)		5 / 12
ILE A 407
VAL A 574
GLY A 551
MET A 557
LEU A 558
0.77A16.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6m03 MAIN PROTEASE
(SARS-CoV-2)		5 / 10
ILE A 281
LEU A 205
LEU A 253
ASP A 216
PHE A 219
1.79A21.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m17 ACE2
(Homo
sapiens)		5 / 12
ILE B 407
VAL B 574
GLY B 551
MET B 557
LEU B 558
0.70A15.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ILE A 497
LEU A 595
GLY A 438
THR A 596
MET A 124
1.34A16.29
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
PHE A 287
LEU A 280
MET A 463
LEU A 245
THR A 246
1.61A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
MET A 668
GLY A 446
THR A 402
LEU A 544
THR A 409
1.65A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
HIS A 309
PHE A 313
LEU A 308
LEU A 245
THR A 246
1.74A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
NSP8
(SARS-CoV-2)		5 / 12
ILE B 119
LEU B 103
VAL A 341
GLY A 327
LEU A 329
1.75A22.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
HIS A 309
PHE A 313
LEU A 308
MET A 242
LEU A 245
1.79A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 450
LEU A 388
VAL A 405
LEU A 544
THR A 409
1.78A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ILE A 450
LEU A 388
GLY A 446
LEU A 544
THR A 409
1.76A14.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6nb7 SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 12
PHE C 782
VAL C1047
GLY C 867
PHE C1034
MET C 884
1.50A12.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
PHE A 800
VAL A1065
GLY A 885
PHE A1052
MET A 902
1.49A11.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6vw1 ACE2
(Homo
sapiens)		5 / 10
LEU B 148
LEU B 162
ASP B 136
SER B 167
GLU B 166
1.73A17.54
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE B 805
LEU B 877
VAL B1033
THR B 881
THR B 723
1.41A11.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6vxx SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
LEU C  56
VAL C  36
LEU C 223
ASP C 287
GLU C 191
1.77A12.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 10
LEU B  56
VAL B  36
LEU B 223
ASP B 287
GLU B 191
1.77A12.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6vyb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
ILE C 805
LEU C 877
VAL C1033
THR C 881
THR C 723
1.34A11.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w41 SPIKE PROTEIN S1
(SARS-CoV-2)		5 / 12
PHE C 377
ILE C 434
VAL C 367
PHE C 342
LEU C 387
1.77A18.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6969
VAL A6992
GLY A7006
MET A6809
THR A6989
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
VAL A6842
GLY A6806
PHE A7048
THR A6993
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
VAL C6842
GLY C6806
PHE C7048
THR C6993
1.73A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE A6969
VAL A6992
GLY A7006
MET A6809
THR A6989
1.70A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
VAL A6842
GLY A6806
PHE A7048
THR A6993
1.71A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w75 NSP16
(SARS-CoV-2)		5 / 12
ILE C6969
VAL C6992
GLY C7006
MET C6809
THR C6989
1.68A22.39
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 10
MET B 243
ILE B 123
VAL B 165
PHE B 173
GLU B 167
1.70A20.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 9
MET B 169
LEU B 120
LEU B 101
ILE B 276
PHE B 304
1.74A20.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 9
MET A 169
LEU A 120
LEU A 101
ILE A 276
PHE A 304
1.78A20.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE B 304
LEU B 101
GLY B 163
MET B 169
THR B 168
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 9
MET C 169
LEU C 120
LEU C 101
ILE C 276
PHE C 304
1.74A20.76
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE C 304
LEU C 101
GLY C 163
MET C 169
THR C 168
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 304
LEU A 101
GLY A 163
MET A 169
THR A 168
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
ILE A  65
LEU A  69
GLY A  38
PHE A  56
THR A  35
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
LEU A  69
VAL A  41
GLY A  37
THR A  67
THR A  35
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE C6969
VAL C6992
GLY C7006
MET C6809
THR C6989
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS C6867
VAL C6842
GLY C6806
PHE C7048
THR C6993
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
VAL A6842
GLY A6806
PHE A7048
THR A6993
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wjt 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6969
VAL A6992
GLY A7006
MET A6809
THR A6989
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wkp NUCLEOCAPSID PROTEIN
(SARS-CoV-2)		5 / 12
ILE C 157
LEU C 161
VAL C  72
GLY C 147
PHE C  53
1.76A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS A6867
VAL A6842
GLY A6806
PHE A7048
THR A6993
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
HIS C6867
VAL C6842
GLY C6806
PHE C7048
THR C6993
1.71A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE A6969
VAL A6992
GLY A7006
MET A6809
THR A6989
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wkq NSP16
(SARS-CoV-2)		5 / 12
ILE C6969
VAL C6992
GLY C7006
MET C6809
THR C6989
1.68A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 144
LEU A 163
VAL A 173
GLY A 147
PHE A 177
1.74A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE B 342
ILE B 236
VAL B 304
GLY B 230
LEU B 312
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE B 342
ILE B 236
GLY B 230
PHE B 233
LEU B 312
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
PHE A 342
ILE A 236
GLY A 230
PHE A 233
LEU A 312
1.59A
None
None
SO4  A 410 (-3.9A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE B 281
GLY B 254
PHE B 241
THR B 286
LEU B 201
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wlc URIDYLATE-SPECIFIC
ENDORIBONUCLEASE
(SARS-CoV-2)		5 / 12
ILE A 281
GLY A 254
PHE A 241
THR A 286
LEU A 201
1.60A
None
None
None
None
EDO  A 405 (-4.1A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6969
VAL A6992
GLY A7006
MET A6809
THR A6989
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
HIS A6867
VAL A6842
GLY A6806
PHE A7048
THR A6993
1.72A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wq3 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
ILE A6866
LEU A6959
VAL A6965
GLY A6869
PHE A6954
1.79A
None
None
None
SAH  A7101 (-3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 9
MET A 169
LEU A 120
LEU A 101
ILE A 276
PHE A 304
1.77A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
LEU A  64
VAL A  57
THR A   9
MET A  84
LEU A  87
1.65A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
PHE A 304
LEU A 101
GLY A 163
MET A 169
THR A 168
1.63A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 10
MET A 243
ILE A 123
VAL A 165
PHE A 173
GLU A 167
1.73A21.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
PHE B  29
ILE B  34
GLY B 110
THR B 104
MET B   2
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE B  34
VAL B 108
GLY B 101
PHE B  29
THR B 104
1.70A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE H  34
VAL H 108
GLY H 101
PHE H  29
THR H 104
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yla HEAVY CHAIN
(Homo
sapiens)		5 / 12
PHE H  29
ILE H  34
GLY H 110
THR H 104
MET H   2
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6ym0 HEAVY CHAIN
(Homo
sapiens)		5 / 12
ILE H  34
VAL H 108
GLY H 101
PHE H  29
THR H 104
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE H  34
VAL H 108
GLY H 101
PHE H  29
THR H 104
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PHE H  29
ILE H  34
GLY H 110
THR H 104
MET H   2
1.79A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
ILE B  34
VAL B 108
GLY B 101
PHE B  29
THR B 104
1.69A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		6yor IGG H CHAIN
(Homo
sapiens)		5 / 12
PHE B  29
ILE B  34
GLY B 110
THR B 104
MET B   2
1.80A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
ILE A 450
LEU A 388
VAL A 405
LEU A 544
THR A 409
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 9
MET D  90
LEU D  91
LEU D  98
ASP A 421
PHE A 415
1.77A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
MET A 668
GLY A 446
THR A 402
LEU A 544
THR A 409
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
LEU A  49
VAL A  31
PHE A  35
LEU A 119
THR A 120
1.78A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 10
MET D  90
LEU D  91
LEU D  98
ASP A 421
PHE A 415
1.77A20.30
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 287
LEU A 280
MET A 463
LEU A 245
THR A 246
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
PHE A 287
LEU A 280
MET A 463
LEU A 245
THR A 246
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
MET A 668
GLY A 446
THR A 402
LEU A 544
THR A 409
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 506
ILE A 562
GLY A 559
THR A 567
THR A 540
1.48A
None
None
U  T  10 ( 3.5A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 287
LEU A 280
MET A 463
LEU A 245
THR A 246
1.68A
None