Ligand ID: KTN


Drugbank ID:
DB01026
(Ketoconazole)


Indication:
For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Get human targets for KTN in PDB (known and potential targets)

RESULTS FROM SUB-STRUCTURAL SIMILARITY SEARCHES MAPPED TO LIGAND 'KTN'

Click here for results that match SARS-Cov-2 / COVID-19 structures only
Click here for results that match SARS-related structures only


1) User may click on the DrReposER ID (the second column) to get information on the binding sites and drug molecule.
2) Click View (the second last column) to view matched residues and superposition in the NGL viewer (upper right part).
3) User may also click on the Dock (the last column) to get script for molecular docking in UCSF Chimera through AutoDock Vina.

DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 View Interface RMSD Seq.
Identity (%)		 HETATM Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		1qz8 POLYPROTEIN 1AB
(SARSr-CoV)		6 / 11
SER B  13
ALA B  43
VAL B 110
LEU B 106
ALA B 108
ALA A 108
1.73A15.23
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		1uk3 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
PHE B 291
ALA B 206
ALA B 255
THR B 292
LEU B 250
1.46A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 12
ALA D1155
LEU F 941
VAL E 934
ALA E 938
LEU D 941
1.29A14.18
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		1wnc E2 GLYCOPROTEIN
(SARSr-CoV)		5 / 11
ALA A1155
VAL B 934
ALA B 938
ALA B1155
LEU A 941
1.43A14.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		1z1j 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 291
ALA A 206
LEU A 242
LEU A 268
ALA A 267
LEU A 250
1.68A19.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
(SARSr-CoV)		5 / 11
THR G 146
VAL G 137
LEU G 189
THR G 151
LEU G 174
1.43A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2ahm REPLICASE
POLYPROTEIN 1AB,
HEAVY CHAIN
REPLICASE
POLYPROTEIN 1AB,
LIGHT CHAIN
(SARSr-CoV)		5 / 11
THR A  14
LEU A  64
ALA E 115
THR E  98
LEU A  76
1.43A13.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2ajf ACE2
(Homo
sapiens)		5 / 11
SER B 280
ALA B 251
THR B 282
LEU B 262
ALA B 264
1.44A21.94
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2fe8 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
THR C 169
VAL C 117
LEU C 121
ALA C 140
LEU C 133
1.39A21.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2jzd REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
SER A 585
THR A 612
LEU A 533
ALA A 558
THR A 584
1.45A14.50
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2k7x REPLICASE
POLYPROTEIN 1AB MAIN
PROTEASE
(SARS-COV
Sino1-11)		6 / 11
ALA A 267
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 208
1.79A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		2k87 NSP3 OF REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
GLY A  77
LEU A  25
LEU A 108
THR A  97
LEU A  36
1.30A12.66
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2kqv NSP3
(SARSr-CoV)		6 / 11
PHE A  60
TYR A  61
THR A  83
LEU A 105
ALA A 107
LEU A  77
1.77A20.15
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2q6g REPLICASE
POLYPROTEIN 1AB
(SARS-COV
BJ01)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.46A21.41
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		2wct NSP3
(SARSr-CoV)		5 / 11
SER D 585
THR D 612
LEU D 533
ALA D 558
THR D 584
1.46A19.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3bgf F26G19 FAB
(Mus
musculus)		5 / 11
SER L  76
THR L  74
LEU L  33
ALA L  51
ALA L  50
1.44A18.61
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3d0h ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
TYR A 237
LEU A 278
VAL A 487
LEU A 262
ALA A 264
1.30A22.22
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3e9s NSP3
(SARSr-CoV)		5 / 11
THR A 169
VAL A 117
LEU A 121
ALA A 140
LEU A 133
1.37A20.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ea7 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
ALA A 210
LEU A 287
ALA A 286
ALA A 285
LEU A 282
1.09A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ea8 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 223
ALA A 267
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.73A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 223
ALA A 267
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.73A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ea9 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
ALA A 210
LEU A 287
ALA A 286
ALA A 285
LEU A 282
1.17A20.81
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ebn REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		6 / 12
PHE D 223
ALA D 266
LEU B 205
VAL D 233
LEU D 272
ALA D 234
1.80A15.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3ee7 REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 12
ALA C  43
GLY D 100
LEU C  45
ALA C 107
LEU C  88
1.35A15.33
None
None
GOL  C 123 ( 4.8A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3f9e 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ALA A 267
THR A 225
LEU A 287
VAL A 233
LEU A 272
LEU A 208
1.75A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3i6l HLA, A-24
NUCLEOPROTEIN
PEPTIDE
(Homo
sapiens;
SARSr-CoV)		5 / 12
ALA D  81
TYR D  85
GLY D 120
ALA D 125
LEU F   9
1.30A21.03
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3m3t 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 223
ALA A 267
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.78A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ALA A 267
THR A 225
LEU A 287
VAL A 233
ALA A 234
LEU A 208
1.77A20.14
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3m3v 3C-LIKE PROTEINASE
(SARSr-CoV)		5 / 11
ALA B 210
LEU B 287
ALA B 286
ALA B 285
LEU B 282
1.09A20.90
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3sci ACE2
(Homo
sapiens)		5 / 12
TYR A 237
LEU A 278
VAL A 487
LEU A 262
ALA A 264
1.27A21.65
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 11
SER B 280
ALA B 251
THR B 282
LEU B 262
ALA B 264
1.44A21.84
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3sck ACE2
(Paguma
larvata;
Homo
sapiens;
SARSr-CoV)		5 / 12
TYR A 237
LEU A 278
VAL A 487
LEU A 262
ALA A 264
1.32A22.02
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3sna 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE A 223
ALA A 267
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.78A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		3to2 MD3-C9 PEPTIDE
DERIVED FROM
MEMBRANE
GLYCOPROTEIN
MHC CLASS I ANTIGEN
(Homo
sapiens;
SARS-COV
TJF)		5 / 11
PHE C   4
THR A  73
VAL C   9
ALA A 125
LEU A 156
1.23A8.42
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		3vb6 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
PHE B 223
ALA B 267
LEU B 287
VAL B 212
ALA B 211
LEU B 271
1.64A19.86
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		4hi3 3C-LIKE PROTEINASE
(SARSr-CoV)		6 / 12
ALA B 267
THR B 225
LEU B 287
VAL B 233
LEU B 272
LEU B 208
1.76A19.62
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		4m0w REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 11
THR A 169
VAL A 117
LEU A 121
ALA A 140
LEU A 133
1.43A21.56
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		4ow0 PAPAIN-LIKE PROTEASE
(SARS-COV
Urbani)		5 / 11
THR A 169
VAL A 117
LEU A 121
ALA A 140
LEU A 133
1.38A21.12
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		6 / 12
PHE D 445
THR D 475
VAL D 483
LEU D 468
ALA D 482
THR D 516
1.73A21.12
None
ZN  D 603 ( 4.9A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5c8s GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
TYR D 494
VAL D 316
ALA D 320
ALA D 323
THR D 472
1.46A21.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5c8u GUANINE-N7
METHYLTRANSFERASE
(SARSr-CoV)		5 / 11
SER D 178
ALA D 425
TYR D 296
ALA D 281
LEU D 419
1.42A21.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5e6j POLYUBIQUITIN-B
REPLICASE
POLYPROTEIN 1AB
UBIQUITIN
(SARSr-CoV;
synthetic
construct)		5 / 11
TYR B  59
LEU A 200
ALA A 205
ALA A 182
LEU C  73
1.41A11.41
5MW  B  48 ( 4.9A)
None
None
None
5MW  B  48 ( 4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5e6j REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
THR A 169
VAL A 117
LEU A 121
ALA A 140
LEU A 133
1.41A20.95
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5nfy POLYPROTEIN 1AB
(SARS-COV
Frankfurt
1)		5 / 11
TYR D 494
VAL D 316
ALA D 320
ALA D 323
THR D 472
1.38A21.06
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 260
LEU A 250
VAL A 212
ALA A 211
THR A 224
1.54A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
GLY A 109
THR A 111
LEU A 250
1.67A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
VAL A 204
LEU A 205
ALA A 206
1.77A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.56A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.69A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 185
GLY A 138
LEU A 177
ARG A 105
VAL A 114
1.76A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.69A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
GLY A 251
LEU A 268
VAL A 247
LEU A 242
THR A 257
1.76A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.52A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
ALA A 234
THR A 199
VAL A 204
LEU A 205
ALA A 206
1.78A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5rfc 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5tl7 REPLICASE
POLYPROTEIN 1AB
(SARSr-CoV)		5 / 11
THR B 169
VAL B 117
LEU B 121
ALA B 140
LEU B 133
1.38A20.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		6 / 12
ALA C  36
THR B  30
LEU C  39
ARG C  38
VAL C  29
LEU C  37
1.78A12.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5x29 ENVELOPE SMALL
MEMBRANE PROTEIN
(SARSr-CoV)		5 / 11
SER B  50
ALA C  32
LEU C  39
ALA C  41
ALA C  44
1.46A12.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		5 / 11
THR B 925
VAL B 708
ALA B1038
THR B 922
LEU B 803
1.36A16.27
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5x58 SPIKE GLYCOPROTEIN
(SARS-COV
BJ01)		6 / 12
GLY B 928
THR B 925
VAL B 708
ALA B1038
THR B 922
LEU B 803
1.55A16.25
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
SER A 924
VAL A 708
ALA A1038
THR A 922
LEU A 803
1.42A16.10
SER  A 924 ( 0.0A)
VAL  A 708 ( 0.6A)
ALA  A1038 ( 0.0A)
THR  A 922 ( 0.8A)
LEU  A 803 ( 0.6A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5xlr SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 12
PHE A 551
GLY A 534
THR A 533
LEU C 948
LEU C 959
THR A 559
1.73A16.24
PHE  A 551 ( 1.3A)
GLY  A 534 ( 0.0A)
THR  A 533 ( 0.8A)
LEU  C 948 ( 0.6A)
LEU  C 959 ( 0.6A)
THR  A 559 ( 0.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5y3q REPLICASE
POLYPROTEIN 1A
(SARSr-CoV)		5 / 11
THR A 169
VAL A 117
LEU A 121
ALA A 140
LEU A 133
1.42A21.43
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		5zvm SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
SER A 950
PHE A 952
LEU A 941
ALA A 940
LEU C 948
1.45A12.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		5zvm PAN-COV INHIBITORY
PEPTIDE EK1
SPIKE GLYCOPROTEIN
(SARSr-CoV;
synthetic
construct)		6 / 12
ALA A 940
LEU C 944
VAL a  13
ALA B 940
THR c  14
LEU C 941
1.71A11.17
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6acg SPIKE GLYCOPROTEIN
(SARSr-CoV)		5 / 11
PHE C1057
ALA C 695
THR C 698
ALA B 872
LEU B 876
1.39A16.10
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ack SPIKE GLYCOPROTEIN
(SARSr-CoV)		6 / 12
PHE C 551
GLY C 534
THR C 533
LEU B 948
LEU B 959
THR C 559
1.56A16.24
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ack ACE2
(Homo
sapiens)		5 / 11
SER D 280
ALA D 251
THR D 282
LEU D 262
ALA D 264
1.41A21.67
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6crv SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY C 928
VAL C 708
ALA C1038
THR C 923
LEU C 920
1.31A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6crw SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 12
GLY B  68
THR B  67
LEU B 257
THR B  34
LEU B  60
1.21A16.16
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6cs0 SPIKE
GLYCOPROTEIN,FIBRITI
N
(SARSr-CoV)		5 / 11
PHE B 103
ALA B 233
ALA B 251
ALA B 249
LEU B 235
1.46A16.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6cs2 ACE2
(Homo
sapiens)		5 / 12
TYR D 237
LEU D 278
VAL D 487
LEU D 262
ALA D 264
1.28A22.09
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.55A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 223
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.60A18.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6lze VIRAL PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.56A21.51
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 223
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.60A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A21.46
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 260
LEU A 250
VAL A 212
ALA A 211
THR A 224
1.59A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m0k VIRAL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.55A18.69
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m17 ACE2
(Homo
sapiens)		5 / 12
TYR B 237
LEU B 278
VAL B 487
LEU B 262
ALA B 264
1.33A18.01
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m18 SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 12
ALA C 399
GLY C  53
VAL C 317
ALA C 318
THR C 396
1.15A20.75
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m1d SODIUM-DEPENDENT
NEUTRAL AMINO ACID
TRANSPORTER B(0)AT1
(Homo
sapiens)		5 / 11
SER C 278
ALA C 282
VAL C 125
ALA C 489
ALA C 590
1.46A20.73
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 234
THR B 225
LEU B 287
LEU B 205
LEU B 272
1.60A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE D 291
ALA D 206
ALA D 255
THR D 292
LEU D 250
1.50A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE D 291
ALA D 206
ALA D 255
THR D 292
LEU D 250
1.49A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 234
THR B 199
VAL B 204
LEU B 208
ALA B 206
1.60A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
ALA A 234
THR A 199
VAL A 204
LEU A 208
ALA A 206
1.61A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE C 291
ALA C 206
ALA C 255
THR C 292
LEU C 250
1.53A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE C 291
ALA C 206
ALA C 255
THR C 292
LEU C 250
1.52A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA B 234
THR B 225
LEU B 287
LEU B 208
LEU B 272
1.53A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.56A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 11
ALA B 234
THR B 199
VAL B 204
LEU B 208
ALA B 206
1.62A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
VAL A 204
LEU A 208
ALA A 206
1.59A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2n 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 225
LEU A 287
LEU A 208
LEU A 272
1.52A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.54A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.56A21.36
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m2q 3CL PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A18.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
TYR A 483
VAL A 637
LEU A 638
ALA A 634
THR A 586
1.61A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 512
TYR A 516
THR A 565
LEU A 372
ALA A 376
1.59A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
PHE A 766
GLY A 774
VAL A 720
LEU A 723
LEU A 749
1.59A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR C   9
LEU C  59
ALA D 110
THR D  93
LEU C  71
1.49A12.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
LEU A 131
VAL A 147
LEU A 146
THR A 120
LEU A 127
1.49A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
1.46A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 11
PHE A 313
ALA A 311
LEU A 655
ALA A 656
ALA A 660
1.59A19.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 585
GLY A 590
THR A 591
ALA A 688
THR A 582
1.42A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 12
ALA A 585
GLY A 590
THR A 591
ARG A 750
THR A 582
1.37A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.49A19.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		6 / 11
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
ALA A 656
1.58A19.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		6 / 12
THR A 686
LEU A 351
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.60A18.78
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6m71 NSP12
(SARS-CoV-2)		5 / 11
SER A 518
ALA A 490
TYR A 521
VAL A 495
ALA A 685
1.47A19.34
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6nur NSP12
(SARSr-CoV)		6 / 12
THR A 686
LEU A 351
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.53A17.53
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6nus NSP12
(SARSr-CoV)		5 / 11
ALA A 634
THR A 687
VAL A 662
LEU A 663
ALA A 656
1.40A17.26
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vsb SPIKE GLYCOPROTEIN
(SARS-CoV-2)		5 / 12
GLY C 566
THR C 573
LEU C 533
THR C 588
LEU C 552
1.34A16.33
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vw1 ACE2
(Homo
sapiens)		5 / 12
TYR B 237
LEU B 278
VAL B 487
LEU B 262
ALA B 264
1.34A21.85
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vxs NSP3
(SARS-CoV-2)		5 / 11
ALA B  50
THR A  71
VAL B  41
LEU B  75
ALA B 112
1.44A
None
None
None
SO4  B 201 ( 4.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vxs NSP3
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vxs NSP3
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6vxs NSP3
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
ALA L  19
VAL L  85
ALA L  84
THR L  74
LEU L  78
1.73A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ALA L  19
THR L 102
LEU L  15
THR L  74
LEU L  78
1.73A15.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 12
ALA L  19
VAL L  85
ALA L  84
THR L  74
LEU L  78
1.70A15.88
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE C 377
THR C 385
VAL H 102
LEU H   4
ALA H  93
1.47A20.19
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB HEAVY
CHAIN
SPIKE PROTEIN S1
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE C 377
THR C 385
VAL H 102
LEU H   4
ALA H  93
1.46A17.77
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w41 CR3022 FAB LIGHT
CHAIN
(Homo
sapiens)		5 / 11
SER L  10
ALA L  19
LEU L  15
ALA L  80
THR L 102
1.80A16.38
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w4b NSP9
(SARS-CoV-2)		5 / 12
ALA B  44
GLY A 101
LEU B  46
ALA B 108
LEU B  89
1.35A14.68
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 11
THR A6891
VAL A6859
LEU A6857
ALA A6858
LEU A6959
1.72A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w61 2'-O-METHYLTRANSFERA
SE
(SARS-CoV-2)		5 / 12
THR A6891
VAL A6859
LEU A6857
ALA A6858
LEU A6959
1.70A16.63
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w63 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 223
LEU A 287
VAL A 212
ALA A 211
LEU A 271
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
THR A 149
VAL A  34
LEU A  93
ALA A  38
THR A 146
1.71A16.87
None
None
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
ALA A 112
VAL A 151
LEU A 122
ALA A 154
LEU A 127
1.79A16.87
None
None
None
AMP  A 201 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
GLY A   8
LEU B 126
VAL B 165
LEU B 164
LEU B 153
1.63A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B 132
ALA B 129
GLY B  48
LEU B 164
LEU B 126
1.59A
MES  B 201 ( 3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU A 153
VAL A  95
LEU A 127
ALA A  38
THR A  33
1.72A16.21
None
None
None
AMP  A 201 ( 3.9A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.45A
None
None
AMP  A 201 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
THR B 149
VAL B  34
LEU B  93
ALA B  38
THR B 146
1.72A16.87
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
LEU B 153
VAL B  95
LEU B 127
ALA B  38
THR B  33
1.72A16.21
None
None
None
MES  B 201 ( 3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.48A
None
None
None
MES  B 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
SER B   7
ALA B 154
VAL B 121
LEU B 122
ALA B  89
1.65A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
PHE B 132
GLY B  48
LEU B 140
LEU B 160
LEU B 126
1.79A16.21
MES  B 201 ( 3.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.48A
None
None
AMP  A 201 ( 3.7A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.52A
None
None
None
MES  B 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
ALA A 112
THR A 146
LEU A 122
ALA A 154
LEU A 127
1.79A16.87
None
None
None
AMP  A 201 ( 4.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 12
ALA B 112
TYR B 113
LEU B  75
VAL B  36
LEU B  93
1.75A16.21
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w6y NSP3
(SARS-CoV-2)		5 / 11
ALA B 112
VAL B 151
LEU B 122
ALA B 154
LEU B 127
1.79A16.87
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY A7076
THR A6856
LEU A6959
ALA A6960
LEU A6924
1.67A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 11
THR C6891
VAL C6859
LEU C6857
ALA C6858
LEU C6959
1.75A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
GLY C7076
THR C6856
LEU C6959
ALA C6960
LEU C6924
1.69A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 12
THR C6891
VAL C6859
LEU C6857
ALA C6858
LEU C6959
1.74A17.05
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ALA C6986
THR C6856
LEU C7078
ALA C6960
LEU C7010
1.72A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w75 NSP16
(SARS-CoV-2)		5 / 11
ALA A6986
THR A6856
LEU A7078
ALA A6960
LEU A7010
1.71A17.57
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA A 144
TYR A  95
LEU A  87
ALA A  86
ALA A 153
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA C 144
TYR C  95
LEU C  87
ALA C  86
ALA C 153
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA C 116
LEU C 152
ALA C 149
ALA C 145
LEU C 117
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		6 / 11
PHE C  69
ALA C  68
LEU C 150
ALA C  86
THR C  75
LEU C  80
1.73A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA B 144
TYR B  95
LEU B  87
ALA B  86
ALA B 153
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA B 131
TYR B  71
LEU B  80
ALA B  86
LEU B 150
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
ALA A 131
TYR A  71
LEU A  80
ALA A  86
LEU A 150
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9c PAPAIN-LIKE
PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A  69
ALA A  68
ALA A 149
ALA A  86
LEU A  80
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6w9q 3C-LIKE PROTEINASE
PEPTIDE, NSP9 FUSION
(SARS-CoV-2)		5 / 12
PHE A  -4
THR A  35
LEU A 106
ALA A  30
LEU A   9
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wcf NSP3
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.50A
None
None
None
MES  A 201 ( 3.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wcf NSP3
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.46A
None
None
None
MES  A 201 ( 3.0A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wen NSP3
(SARS-CoV-2)		5 / 11
SER A 139
ALA A 124
VAL A  49
LEU A  53
ALA A  50
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wen NSP3
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wen NSP3
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wey NSP3
(SARS-CoV-2)		5 / 11
PHE A 210
ALA A 231
VAL A 253
ALA A 254
LEU A 292
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wey NSP3
(SARS-CoV-2)		5 / 12
PHE A 210
ALA A 231
VAL A 253
ALA A 254
LEU A 292
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wiq NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR A   9
LEU A  59
ALA B 110
THR B  93
LEU A  71
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wjt NSP10
(SARS-CoV-2)		5 / 11
VAL B4274
ALA D4276
ALA D4277
THR D4292
LEU D4284
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wkq NSP10
(SARS-CoV-2)		5 / 11
VAL B4274
ALA D4276
ALA D4277
THR D4292
LEU D4284
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wnp 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.50A
None
None
APR  A 201 (-3.8A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.54A
None
None
APR  A 201 (-3.8A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.51A
None
None
APR  D 201 (-3.6A)
APR  D 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.53A
None
None
APR  C 201 (-3.8A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.52A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.56A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-3.3A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.49A
None
None
APR  C 201 (-3.8A)
APR  C 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6woj REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.55A
None
None
APR  D 201 (-3.6A)
APR  D 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wqd NSP7
NSP8
(SARS-CoV-2)		5 / 12
THR B  93
LEU A  60
LEU A  71
THR A   9
LEU A  56
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wqf 3C-LIKE PROTEINASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
THR A 168
LEU A 152
ALA A 149
ALA A 145
THR A 115
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
SER A 262
LEU A 290
ALA A 288
THR A 119
LEU A 101
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		6 / 11
PHE A  69
ALA A  68
ALA A 149
ALA A  86
THR A  75
LEU A  80
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 12
PHE A  69
ALA A  68
ALA A 149
THR A  75
LEU A  80
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
ALA A 144
TYR A  95
LEU A  87
ALA A  86
ALA A 153
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6wrh PEPTIDASE C16
(SARS-CoV-2)		5 / 11
ALA A 131
TYR A  71
LEU A  80
ALA A  86
LEU A 150
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
GLY A 109
THR A 111
LEU A 250
1.67A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.73A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.52A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
ALA A 234
THR A 199
VAL A 204
LEU A 205
ALA A 206
1.79A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.73A19.60
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
VAL A 204
LEU A 205
ALA A 206
1.78A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
LEU A 242
LEU A 205
ALA A 206
THR A 198
1.80A19.32
None
None
None
None
DMS  A 404 (-3.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
GLY A 251
LEU A 268
VAL A 247
LEU A 242
THR A 257
1.74A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yb7 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 260
LEU A 250
VAL A 212
ALA A 211
THR A 224
1.54A19.32
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
THR D  93
LEU C  71
ALA C  65
THR C   9
LEU C  56
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 12
THR D  93
LEU C  60
LEU C  71
THR C   9
LEU C  56
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yhu REPLICASE
POLYPROTEIN 1A
(SARS-CoV-2)		5 / 11
THR B  93
LEU A  71
ALA A  65
THR A   9
LEU A  56
1.50A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA L  19
VAL L  91
ALA L  90
THR L  80
LEU L  84
1.60A
None
1PE  L1603 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE A 377
THR A 385
VAL B 108
LEU B   4
ALA B  97
1.40A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 11
ALA L  19
VAL L  91
ALA L  90
THR L  80
LEU L  84
1.61A
None
1PE  L1603 ( 4.8A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla LIGHT CHAIN
(Homo
sapiens)		5 / 12
ALA C  19
THR C 108
LEU C  15
THR C  80
LEU C  84
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yla HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE A 377
THR A 385
VAL B 108
LEU B   4
ALA B  97
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ym0 HEAVY CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ynq REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 11
ALA C  19
VAL C  91
ALA C  90
THR C  80
LEU C  84
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 11
ALA L  19
VAL L  91
ALA L  90
THR L  80
LEU L  84
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG L CHAIN
(Homo
sapiens)		5 / 12
ALA L  19
VAL L  91
ALA L  90
THR L  80
LEU L  84
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE E 377
THR E 385
VAL H 108
LEU H   4
ALA H  97
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 12
PHE A 377
THR A 385
VAL B 108
LEU B   4
ALA B  97
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yor IGG H CHAIN
SPIKE GLYCOPROTEIN
(Homo
sapiens;
SARS-CoV-2)		5 / 11
PHE A 377
THR A 385
VAL B 108
LEU B   4
ALA B  97
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.61A
None
None
PEG  A 404 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.52A
 CL  A 406 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
THR A 225
VAL A 233
LEU A 272
ALA A 234
LEU A 205
1.60A
None
None
PEG  A 404 (-3.4A)
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.51A
 CL  A 406 (-4.4A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6yt8 REPLICASE
POLYPROTEIN 1AB
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.60A
None
PEG  A 404 (-3.0A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.51A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE E   6
ALA E  27
VAL E  49
ALA E  50
LEU E  88
1.52A
None
None
None
EPE  E 202 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.50A
None
None
EDO  D 209 (-4.6A)
EDO  D 206 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE E   6
ALA E  27
VAL E  49
ALA E  50
LEU E  88
1.49A
None
None
None
EPE  E 202 (-3.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.47A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D   8
LEU E 126
VAL E 165
LEU E 164
LEU E 153
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.45A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
SER E   7
ALA E 154
VAL E 121
LEU E 122
ALA E  89
1.61A
None
EDO  E 205 (-4.4A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywk NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.46A
None
None
EDO  D 209 (-4.6A)
EDO  D 206 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.48A
None
None
APR  A 201 (-3.7A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.47A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.48A
None
None
APR  D 201 (-3.7A)
APR  D 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.52A
None
None
APR  B 201 (-3.7A)
APR  B 201 (-3.5A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.54A
None
None
APR  C 201 (-3.6A)
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE E   6
ALA E  27
VAL E  49
ALA E  50
LEU E  88
1.52A
None
None
APR  E 201 (-3.7A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE D   6
ALA D  27
VAL D  49
ALA D  50
LEU D  88
1.52A
None
None
APR  D 201 (-3.7A)
APR  D 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B 132
ALA B 129
GLY B  48
LEU B 164
LEU B 126
1.57A
APR  B 201 (-3.5A)
APR  B 201 (-3.6A)
APR  B 201 (-3.5A)
None
APR  B 201 (-4.7A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.49A
None
None
APR  C 201 (-3.6A)
APR  C 201 (-3.6A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A 132
ALA A 129
GLY A  48
LEU A 164
LEU A 126
1.59A
APR  A 201 (-3.7A)
APR  A 201 ( 3.7A)
APR  A 201 (-3.4A)
None
APR  A 201 (-4.8A)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE E   6
ALA E  27
VAL E  49
ALA E  50
LEU E  88
1.48A
None
None
APR  E 201 (-3.7A)
APR  E 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
GLY D   8
LEU E 126
VAL E 165
LEU E 164
LEU E 153
1.58A
None
APR  E 201 (-4.7A)
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywl NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.53A
None
None
APR  A 201 (-3.7A)
APR  A 201 (-3.4A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B 132
ALA B 129
LEU B 164
ALA B  21
LEU B 126
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.46A
None
None
None
MES  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE A 132
ALA A 129
GLY A  48
LEU A 164
LEU A 126
1.60A
MES  A 201 (-3.5A)
None
None
None
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.50A
None
None
None
MES  C 201 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE C   6
ALA C  27
VAL C  49
ALA C  50
LEU C  88
1.46A
None
None
None
MES  C 201 ( 3.8A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 12
PHE B   6
ALA B  27
VAL B  49
ALA B  50
LEU B  88
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		6ywm NSP3 MACRODOMAIN
(SARS-CoV-2)		5 / 11
PHE A   6
ALA A  27
VAL A  49
ALA A  50
LEU A  88
1.49A
None
None
None
MES  A 201 ( 3.7A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.55A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bqy MAIN PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
1.39A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
THR A 540
VAL A 662
LEU A 663
ALA A 690
THR A 556
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 11
THR D  89
VAL C  66
ALA C  65
THR C   9
LEU C  56
1.33A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 313
ALA A 311
LEU A 655
ALA A 656
ALA A 660
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 694
ALA A 634
LEU A 655
ALA A 656
THR A 680
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
THR A 687
VAL A 662
LEU A 663
ALA A 656
1.46A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 11
PHE A 340
ALA A 379
LEU A 673
ALA A 400
LEU B 117
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		6 / 12
THR A 686
LEU A 351
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.64A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 12
PHE A 340
ALA A 379
LEU A 673
ALA A 400
LEU B 117
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 12
ALA A 585
GLY A 590
THR A 591
ALA A 688
THR A 582
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		6 / 11
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
ALA A 656
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
NSP8
(SARS-CoV-2)		5 / 11
ALA B 150
TYR B 149
ALA A 399
ALA A 382
LEU B 122
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
THR A 531
VAL A 373
LEU A 372
ALA A 376
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 12
PHE A 766
GLY A 774
VAL A 720
LEU A 723
LEU A 749
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP12
(SARS-CoV-2)		5 / 11
PHE A 694
ALA A 690
LEU A 655
ALA A 656
THR A 680
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7btf NSP7
NSP8
(SARS-CoV-2)		5 / 12
THR D  89
VAL C  66
ALA C  65
THR C   9
LEU C  56
1.31A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 260
LEU A 250
VAL A 212
ALA A 211
THR A 224
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.57A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 11
PHE A 291
ALA A 206
ALA A 255
THR A 292
LEU A 250
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7buy VIRUS MAIN PROTEASE
(SARS-CoV-2)		5 / 12
ALA A 234
THR A 199
LEU A 227
VAL A 204
LEU A 205
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		6 / 12
THR A 686
LEU A 351
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.67A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
1.38A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
PHE A 694
ALA A 690
LEU A 655
ALA A 656
THR A 680
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
THR A 462
LEU A 470
VAL A 315
ALA A 311
LEU A 469
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
NSP7
(SARS-CoV-2)		5 / 11
PHE C  49
THR C   9
LEU C  17
ALA A 443
LEU C  35
1.62A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 694
ALA A 690
LEU A 655
ALA A 656
THR A 680
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
THR A 687
VAL A 662
LEU A 663
ALA A 656
1.53A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
SER A 236
ALA A  43
VAL A 704
LEU A 707
ALA A 706
1.30A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 12
ALA A 585
GLY A 590
THR A 591
ALA A 688
THR A 582
1.43A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		6 / 11
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 660
ALA A 656
1.59A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
(SARS-CoV-2)		5 / 11
PHE A 313
ALA A 311
LEU A 655
ALA A 656
ALA A 660
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv1 NSP12
NSP8
(SARS-CoV-2)		5 / 12
PHE A 340
ALA A 379
LEU A 673
ALA A 399
LEU B 117
1.41A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 766
GLY A 774
VAL A 720
LEU A 723
LEU A 749
1.54A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
ALA A 634
THR A 686
VAL A 662
LEU A 663
ALA A 656
1.32A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.49A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
SER A 236
ALA A  43
VAL A 704
LEU A 707
ALA A 706
1.37A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 313
ALA A 311
LEU A 655
ALA A 656
ALA A 660
1.52A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
NSP8
(SARS-CoV-2)		5 / 11
ALA B 150
TYR B 149
ALA A 399
ALA A 382
LEU B 122
1.48A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		6 / 12
THR A 686
LEU A 351
VAL A 662
LEU A 663
ALA A 660
LEU A 655
1.56A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
PHE A 571
THR A 531
VAL A 373
LEU A 372
ALA A 376
1.58A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
ALA A 585
GLY A 590
THR A 591
ALA A 688
THR A 582
1.48A
None
A  T  13 ( 3.1A)
None
F86  P 102 ( 4.1A)
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 656
LEU A 636
1.60A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 11
THR A 686
VAL A 662
LEU A 663
ALA A 660
ALA A 656
1.61A
None
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		7bv2 NSP12
(SARS-CoV-2)		5 / 12
PHE A 571
THR A 531
VAL A 373
LEU A 372
ALA A 376
1.60A
None