(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1iut | PAB | Aminobenzoic acid (DB02362) | Aminobenzoic acid is a drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. | P-HYDROXYBENZOATE HYDROXYLASE (Pseudomonas aeruginosa) | FAD_binding_3 | ||
| 1lqp | FCN | Fosfomycin (DB00828) | Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections. | PROBABLE FOSFOMYCIN RESISTANCE PROTEIN (Pseudomonas aeruginosa) | Glyoxalase | ||
| 1nki | PPF | Foscarnet (DB00529) | Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections. | PROBABLE FOSFOMYCIN RESISTANCE PROTEIN (Pseudomonas aeruginosa) | Glyoxalase | ||
| 2xat | CLM | Chloramphenicol (DB00446) | Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. | XENOBIOTIC ACETYLTRANSFERASE (Pseudomonas aeruginosa) | Hexapep | ||
| 3lt5 | BLQ | Balsalazide (DB01014) | Balsalazide is an aminosalicylate used to treat ulcerative colitis. | FMN-DEPENDENT NADH-AZOREDUCTASE 1 (Pseudomonas aeruginosa) | Flavodoxin_2 | ||
| 3pbs | AZR | Aztreonam (DB00355) | Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. | PENICILLIN-BINDING PROTEIN 3 (Pseudomonas aeruginosa) | PBP_dimerTranspeptidase | ||
| 3r6w | NFZ | Nitrofural (DB00336) | Nitrofural is a topical antibacterial for the prevention and treatment of bacterial infections of the skin. | FMN-DEPENDENT NADH-AZOREDUCTASE 1 (Pseudomonas aeruginosa) | Flavodoxin_2 | ||
| 3ret | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | SALICYLATE BIOSYNTHESIS PROTEIN PCHB (Pseudomonas aeruginosa) | CM_2 | ||
| 4c1d | X8Z | Captopril (DB01197) | Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. | BETA-LACTAMASE CLASS B VIM-2 (Pseudomonas aeruginosa) | Lactamase_B | ||
| 4ebk | TOY | Tobramycin (DB00684) | Tobramycin is an aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. | AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE (Pseudomonas aeruginosa) | AadA_CNTP_transf_2 | ||
| 4kos | 4KO | Cefmetazole (DB00274) | Cefmetazole is a cephalosporin antibiotic used to treat a variety of bacterial infections. | UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa) | Acetyltransf_1 | ||
| 4kot | CE3 | Cefotaxime (DB00493) | Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. | UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa) | Acetyltransf_1 | ||
| 4kou | C04 | Cefixime (DB00671) | Cefixime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. | UNCHARACTERIZED PROTEIN (Pseudomonas aeruginosa) | Acetyltransf_1 | ||
| 4nr0 | TCL | Triclosan (DB08604) | Triclosan is an antimicrobial agent in clinical setting for disinfection, and prevention of spread and growth of bacteria, fungus, and mildew. | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] FABI (Pseudomonas aeruginosa) | adh_short_C2 | ||
| 4oae | CLM | Chloramphenicol (DB00446) | Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. | GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794 (Pseudomonas aeruginosa) | Acetyltransf_1 | ||
| 4qd3 | 5AE | Azacitidine (DB00928) | Azacitidine is a pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome. | PEPTIDYL-TRNA HYDROLASE (Pseudomonas aeruginosa) | Pept_tRNA_hydro | ||
| 4qu3 | 1RG | Ertapenem (DB00303) | Ertapenem is a carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. | BETA-LACTAMASE GES-2 (Pseudomonas aeruginosa) | Beta-lactamase2 | ||
| 4umj | BFQ | Ibandronate (DB00710) | Ibandronate is a bisphosphonate used to treat osteoporosis in postmenopausal women. | GERANYLTRANSTRANSFERASE (Pseudomonas aeruginosa) | polyprenyl_synt | ||
| 5cfs | TOY | Tobramycin (DB00684) | Tobramycin is an aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections. | AAD(2''),GENTAMICIN 2''-NUCLEOTIDYLTRANSFERASE,GENTAMICIN RESISTANCE PROTEIN (Pseudomonas aeruginosa) | Aminoglyc_resit | ||
| 5ltv | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | CHEMOTACTIC TRANSDUCER PCTC (Pseudomonas aeruginosa) | dCache_1 | ||
| 6fu4 | HSM | Histamine (DB05381) | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | PROBABLE CHEMOTAXIS TRANSDUCER (Pseudomonas aeruginosa pao1) | NA | ||
| 6klk | URF | Fluorouracil (DB00544) | Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. | D-HYDANTOINASE/DIHYDROPYRIMIDINASE (Pseudomonas aeruginosa (strain atcc 15692 / dsm 22644 / cip 104116 / jcm 14847 / lmg 12228 / 1c / prs 101 / pao1)) | Amidohydro_1 | ||
| 6mb5 | NMY | Framycetin (DB00452) | Framycetin is an aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus. | AAC(3)-IIIB PROTEIN (Pseudomonas aeruginosa) | Antibiotic_NAT | ||
| 6mb7 | PAR | Paromomycin (DB01421) | Paromomycin is an aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma. | AAC(3)-IIIB PROTEIN (Pseudomonas aeruginosa) | Antibiotic_NAT | ||
| 6rzr | 8YF | Imipenem (DB01598) | Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. | BETA-LACTAMASE (Pseudomonas aeruginosa) | NA | ||
| 6un1 | TJ7 | Temocillin (DB12343) | Temocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection. | PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI (Pseudomonas aeruginosa) | PBP_dimerTranspeptidase | ||
| 6un3 | XT8 | Ticarcillin (DB01607) | Ticarcillin is a beta lactam antibiotic used to treat a variety of infections in the body. | PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI (Pseudomonas aeruginosa) | PBP_dimerTranspeptidase | ||
| 6vje | RB6 | Ceftobiprole (DB04918) | Ceftobiprole is a cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria. | PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI (Pseudomonas aeruginosa) | PBP_dimerTranspeptidase | ||
| 7cia | MPB | Methylparaben (DB14212) | Methylparaben is used in allergenic testing. | UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE (Pseudomonas aeruginosa pao1) | LpxC | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |