Results: Ligand

Ligand ID: X8Z

Drugbank ID:
Captopril
(DB01197)

Indication:
Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.

LIST OF BINDING INTERFACES for query 'DB01197'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2X8Z_A_X8ZA1615	2x8z	X8Z	Captopril (DB01197)	Drosophila melanogaster	ANGIOTENSIN CONVERTING ENZYME	Peptidase_M2	13	GLN A 265 HIS A 337 ALA A 338 THR A 364 HIS A 367 GLU A 368 HIS A 371 GLU A 395 PHE A 441 LYS A 495 HIS A 497 TYR A 504 TYR A 507	X8Z A1615
3LUS_B_X8ZB1001	3lus	X8Z	Captopril (DB01197)	Vibrio cholerae o1 biovar el tor	ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN	OsmC	13	TYR B 37 PRO B 38 PRO B 50 GLU B 51 CYS A 61 ASN A 64 ALA A 65 HIS A 68 ILE B 88 PHE B 96 VAL A 123 CYS A 124 PRO A 125	X8Z B1001
4C1D_A_X8ZA350	4c1d	X8Z	Captopril (DB01197)	Pseudomonas aeruginosa	BETA-LACTAMASE CLASS B VIM-2	Lactamase_B	10	PHE A 62 TYR A 67 TRP A 87 HIS A 114 HIS A 116 ASP A 118 HIS A 179 CYS A 198 ASN A 210 HIS A 240	X8Z A 350
4C1F_A_X8ZA300	4c1f	X8Z	Captopril (DB01197)	Serratia marcescens	BETA-LACTAMASE IMP-1	NA	14	VAL A 43 TRP A 46 VAL A 49 PHE A 69 HIS A 95 HIS A 97 ASP A 99 HIS A 157 CYS A 176 LYS A 179 GLY A 184 ASN A 185 HIS A 215 GLU B 217	X8Z A 300
4C1H_A_X8ZA305	4c1h	X8Z	Captopril (DB01197)	Bacillus cereus	BETA-LACTAMASE 2	Lactamase_B	11	VAL A 69 TRP A 89 HIS A 116 HIS A 118 ASP A 120 HIS A 179 CYS A 198 LYS A 201 GLY A 209 ASN A 210 HIS A 240	X8Z A 305
4C2P_A_X8ZA709	4c2p	X8Z	Captopril (DB01197)	Homo sapiens	ANGIOTENSIN-CONVERTING ENZYME	Peptidase_M2	12	GLN A 281 HIS A 353 ALA A 354 HIS A 383 GLU A 384 HIS A 387 GLU A 411 PHE A 457 LYS A 511 HIS A 513 TYR A 520 TYR A 523	X8Z A 709
4DPR_A_X8ZA702	4dpr	X8Z	Captopril (DB01197)	Homo sapiens	LEUKOTRIENE A-4 HYDROLASE	Leuk-A4-hydro_C Peptidase_M1 Peptidase_M1_N	13	TYR A 267 GLY A 268 GLY A 269 GLU A 271 VAL A 292 HIS A 295 GLU A 296 HIS A 299 GLU A 318 TYR A 378 TYR A 383 ARG A 563 LYS A 565	X8Z A 702
4PQA_A_X8ZA401	4pqa	X8Z	Captopril (DB01197)	Neisseria meningitidis	SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE	M20_dimer Peptidase_M20	14	HIS A 68 ASP A 101 GLU A 135 GLU A 136 GLU A 164 PRO A 165 ARG A 179 GLY A 324 GLY A 325 THR A 326 SER A 327 ASN A 346 ILE A 349 HIS A 350	X8Z A 401
5AYA_A_X8ZA307	5aya	X8Z	Captopril (DB01197)	Serratia marcescens	METALLO-BETA-LACTAMASE	Lactamase_B	13	HIS A 72 HIS A 74 ASP A 76 HIS A 77 GLN A 113 HIS A 150 SER A 175 THR A 177 VAL A 179 HIS A 215 GLU A 217 VAL A 218 ARG A 252	X8Z A 307
5ZIO_A_X8ZA303	5zio	X8Z	Captopril (DB01197)	Klebsiella pneumoniae	METALLO-BETA-LACTAMASE TYPE 2	Lactamase_B	12	MET A 40 PHE A 43 VAL A 46 TRP A 66 HIS A 93 HIS A 95 ASP A 97 HIS A 162 CYS A 181 GLY A 192 ASN A 193 HIS A 223	X8Z A 303
6U10_A_X8ZA303	6u10	X8Z	Captopril (DB01197)	Stenotrophomonas maltophilia (strain k279a)	PUTATIVE METALLO-BETA-LACTAMASE L1 (BETA-LACTAMASE TYPE II) (EC 3.5.2.6) (PENICILLINASE)	Lactamase_B	11	TYR A 32 TRP A 38 HIS A 105 HIS A 107 ASP A 109 HIS A 110 PHE A 145 ILE A 149 HIS A 181 PRO A 210 HIS A 246	X8Z A 303
6U10_A_X8ZA305	6u10	X8Z	Captopril (DB01197)	Stenotrophomonas maltophilia (strain k279a)	PUTATIVE METALLO-BETA-LACTAMASE L1 (BETA-LACTAMASE TYPE II) (EC 3.5.2.6) (PENICILLINASE)	Lactamase_B	4	VAL A 133 ALA A 136 ARG A 137 ASN A 141	X8Z A 305
6V61_A_X8ZA304	6v61	X8Z	Captopril (DB01197)	NA	BETA-LACTAMASE	Lactamase_B	11	ILE A 69 TRP A 89 HIS A 116 HIS A 118 SER A 119 ASP A 120 HIS A 180 CYS A 199 GLY A 210 ASN A 211 HIS A 241	X8Z A 304
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2X8Z_A_X8ZA1615","2x8z","X8Z","Captopril (DB01197)","Drosophila melanogaster","ANGIOTENSIN CONVERTING ENZYME","Peptidase_M2",13,"GLN A 265;HIS A 337;ALA A 338;THR A 364;HIS A 367;GLU A 368;HIS A 371;GLU A 395;PHE A 441;LYS A 495;HIS A 497;TYR A 504;TYR A 507","X8Z A1615\r"],["3LUS_B_X8ZB1001","3lus","X8Z","Captopril (DB01197)","Vibrio cholerae o1 biovar el tor","ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN","OsmC",13,"TYR B  37;PRO B  38;PRO B  50;GLU B  51;CYS A  61;ASN A  64;ALA A  65;HIS A  68;ILE B  88;PHE B  96;VAL A 123;CYS A 124;PRO A 125","X8Z B1001\r"],["4C1D_A_X8ZA350","4c1d","X8Z","Captopril (DB01197)","Pseudomonas aeruginosa","BETA-LACTAMASE CLASS B VIM-2","Lactamase_B",10,"PHE A  62;TYR A  67;TRP A  87;HIS A 114;HIS A 116;ASP A 118;HIS A 179;CYS A 198;ASN A 210;HIS A 240","X8Z A 350\r"],["4C1F_A_X8ZA300","4c1f","X8Z","Captopril (DB01197)","Serratia marcescens","BETA-LACTAMASE IMP-1","NA",14,"VAL A  43;TRP A  46;VAL A  49;PHE A  69;HIS A  95;HIS A  97;ASP A  99;HIS A 157;CYS A 176;LYS A 179;GLY A 184;ASN A 185;HIS A 215;GLU B 217","X8Z A 300\r"],["4C1H_A_X8ZA305","4c1h","X8Z","Captopril (DB01197)","Bacillus cereus","BETA-LACTAMASE 2","Lactamase_B",11,"VAL A  69;TRP A  89;HIS A 116;HIS A 118;ASP A 120;HIS A 179;CYS A 198;LYS A 201;GLY A 209;ASN A 210;HIS A 240","X8Z A 305\r"],["4C2P_A_X8ZA709","4c2p","X8Z","Captopril (DB01197)","Homo sapiens","ANGIOTENSIN-CONVERTING ENZYME","Peptidase_M2",12,"GLN A 281;HIS A 353;ALA A 354;HIS A 383;GLU A 384;HIS A 387;GLU A 411;PHE A 457;LYS A 511;HIS A 513;TYR A 520;TYR A 523","X8Z A 709\r"],["4DPR_A_X8ZA702","4dpr","X8Z","Captopril (DB01197)","Homo sapiens","LEUKOTRIENE A-4 HYDROLASE","Leuk-A4-hydro_C;Peptidase_M1;Peptidase_M1_N",13,"TYR A 267;GLY A 268;GLY A 269;GLU A 271;VAL A 292;HIS A 295;GLU A 296;HIS A 299;GLU A 318;TYR A 378;TYR A 383;ARG A 563;LYS A 565","X8Z A 702\r"],["4PQA_A_X8ZA401","4pqa","X8Z","Captopril (DB01197)","Neisseria meningitidis","SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE","M20_dimer;Peptidase_M20",14,"HIS A  68;ASP A 101;GLU A 135;GLU A 136;GLU A 164;PRO A 165;ARG A 179;GLY A 324;GLY A 325;THR A 326;SER A 327;ASN A 346;ILE A 349;HIS A 350","X8Z A 401\r"],["5AYA_A_X8ZA307","5aya","X8Z","Captopril (DB01197)","Serratia marcescens","METALLO-BETA-LACTAMASE","Lactamase_B",13,"HIS A  72;HIS A  74;ASP A  76;HIS A  77;GLN A 113;HIS A 150;SER A 175;THR A 177;VAL A 179;HIS A 215;GLU A 217;VAL A 218;ARG A 252","X8Z A 307\r"],["5ZIO_A_X8ZA303","5zio","X8Z","Captopril (DB01197)","Klebsiella pneumoniae","METALLO-BETA-LACTAMASE TYPE 2","Lactamase_B",12,"MET A  40;PHE A  43;VAL A  46;TRP A  66;HIS A  93;HIS A  95;ASP A  97;HIS A 162;CYS A 181;GLY A 192;ASN A 193;HIS A 223","X8Z A 303\r"],["6U10_A_X8ZA303","6u10","X8Z","Captopril (DB01197)","Stenotrophomonas maltophilia (strain k279a)","PUTATIVE METALLO-BETA-LACTAMASE L1 (BETA-LACTAMASE TYPE II) (EC 3.5.2.6) (PENICILLINASE)","Lactamase_B",11,"TYR A  32;TRP A  38;HIS A 105;HIS A 107;ASP A 109;HIS A 110;PHE A 145;ILE A 149;HIS A 181;PRO A 210;HIS A 246","X8Z A 303\r"],["6U10_A_X8ZA305","6u10","X8Z","Captopril (DB01197)","Stenotrophomonas maltophilia (strain k279a)","PUTATIVE METALLO-BETA-LACTAMASE L1 (BETA-LACTAMASE TYPE II) (EC 3.5.2.6) (PENICILLINASE)","Lactamase_B",4,"VAL A 133;ALA A 136;ARG A 137;ASN A 141","X8Z A 305\r"],["6V61_A_X8ZA304","6v61","X8Z","Captopril (DB01197)","NA","BETA-LACTAMASE","Lactamase_B",11,"ILE A  69;TRP A  89;HIS A 116;HIS A 118;SER A 119;ASP A 120;HIS A 180;CYS A 199;GLY A 210;ASN A 211;HIS A 241","X8Z A 304\r"]]