Ligand ID: 8YF

Drugbank ID:
Imipenem
(DB01598)

Indication:
Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections.

LIST OF BINDING INTERFACES for query 'DB01598'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5YPI_A_8YFA303	5ypi	8YF	Imipenem (DB01598)	Escherichia coli	METALLO-BETA-LACTAMASE NDM-1	Lactamase_B	18	GLY E  69 PHE A  70 PHE E  70 VAL A  73 TRP A  93 HIS A 120 HIS A 122 GLN A 123 ASP A 124 HIS A 189 CYS A 208 LYS A 211 LYS E 216 SER A 217 LEU A 218 GLY A 219 ASN A 220 HIS A 250	8YF A 303		Details
6RZR_A_8YFA311	6rzr	8YF	Imipenem (DB01598)	Pseudomonas aeruginosa	BETA-LACTAMASE	NA	16	VAL A  25 TRP A  28 VAL A  31 PHE A  51 HIS A  77 HIS A  79 SER A  80 ASP A  81 HIS A 139 CYS A 158 LYS A 161 GLY A 164 LEU A 165 GLY A 166 ASN A 167 HIS A 197	8YF A 311		Details
7LNL_A_8YFA301	7lnl	8YF	Imipenem (DB01598)	Klebsiella pneumoniae	CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC	Beta-lactamase2	17	CYS A  69 GLY A  70 LYS A  73 TRP A 105 SER A 130 ASN A 132 GLU A 166 LEU A 167 ASN A 170 THR A 216 ARG A 220 LYS A 234 THR A 235 GLY A 236 THR A 237 CYS A 238 GLU A 276	8YF A 301		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5YPI_A_8YFA303","5ypi","8YF","Imipenem (DB01598)","Escherichia coli","METALLO-BETA-LACTAMASE NDM-1","Lactamase_B",18,"GLY E 69;PHE A 70;PHE E 70;VAL A 73;TRP A 93;HIS A 120;HIS A 122;GLN A 123;ASP A 124;HIS A 189;CYS A 208;LYS A 211;LYS E 216;SER A 217;LEU A 218;GLY A 219;ASN A 220;HIS A 250","8YF A 303\r"],["6RZR_A_8YFA311","6rzr","8YF","Imipenem (DB01598)","Pseudomonas aeruginosa","BETA-LACTAMASE","NA",16,"VAL A 25;TRP A 28;VAL A 31;PHE A 51;HIS A 77;HIS A 79;SER A 80;ASP A 81;HIS A 139;CYS A 158;LYS A 161;GLY A 164;LEU A 165;GLY A 166;ASN A 167;HIS A 197","8YF A 311\r"],["7LNL_A_8YFA301","7lnl","8YF","Imipenem (DB01598)","Klebsiella pneumoniae","CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC","Beta-lactamase2",17,"CYS A 69;GLY A 70;LYS A 73;TRP A 105;SER A 130;ASN A 132;GLU A 166;LEU A 167;ASN A 170;THR A 216;ARG A 220;LYS A 234;THR A 235;GLY A 236;THR A 237;CYS A 238;GLU A 276","8YF A 301\r"]]