Results: Ligand

Ligand ID: HSM

Drugbank ID:
Histamine
(DB05381)

Indication:
Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains.

LIST OF BINDING INTERFACES for query 'DB05381'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1AVN_A_HSMA264	1avn	HSM	Histamine (DB05381)	Homo sapiens	CARBONIC ANHYDRASE II	Carb_anhydrase	4	ASN A 62 HIS A 64 ASN A 67 GLN A 92	HSM A 264
1IKE_A_HSMA190	1ike	HSM	Histamine (DB05381)	Rhodnius prolixus	NITROPHORIN 4	Nitrophorin	9	ASP A 30 GLU A 32 HIS A 59 THR A 121 LEU A 123 LEU A 130 GLY A 131 ASP A 132 LEU A 133	HSM A 190
1JQD_A_HSMA600	1jqd	HSM	Histamine (DB05381)	Homo sapiens	HISTAMINE N-METHYLTRANSFERASE	Methyltransf_23	10	PHE A 22 GLU A 28 GLN A 143 TYR A 146 VAL A 173 TRP A 179 TRP A 183 PHE A 243 ASN A 283 LEU A 285	HSM A 600
1KAR_A_HSMA502	1kar	HSM	Histamine (DB05381)	Escherichia coli	HISTIDINOL DEHYDROGENASE	Histidinol_dh	11	LEU A 138 SER A 140 SER A 237 HIS A 262 GLU A 326 ASP A 360 TYR A 361 HIS A 367 GLU B 414 LEU B 416 HIS B 419	HSM A 502
1QFT_A_HSMA176	1qft	HSM	Histamine (DB05381)	Rhipicephalus appendiculatus	PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2)	His_binding	10	SER A 20 LEU A 21 ASP A 24 TYR A 29 VAL A 51 PHE A 98 TYR A 100 ASP A 120 ILE A 122 TRP A 137	HSM A 176
1QFT_A_HSMA177	1qft	HSM	Histamine (DB05381)	Rhipicephalus appendiculatus	PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2)	His_binding	10	TYR A 36 ASP A 39 VAL A 41 TRP A 42 GLU A 82 TYR A 100 PHE A 108 ASP A 110 VAL A 124 GLU A 135	HSM A 177
1U18_A_HSMA401	1u18	HSM	Histamine (DB05381)	Rhodnius prolixus	NITROPHORIN 1	Nitrophorin	7	ASP A 31 GLU A 33 THR A 122 LEU A 124 LEU A 131 GLY A 132 LEU A 134	HSM A 401
2QEB_A_HSMA145	2qeb	HSM	Histamine (DB05381)	Anopheles gambiae	D7R4 PROTEIN	NA	11	GLU A 7 ILE A 21 ARG A 22 TYR A 24 ILE A 36 VAL A 39 TYR A 94 PHE A 110 ASP A 111 GLU A 114 MET A 135	HSM A 145
2X45_A_HSMA1160	2x45	HSM	Histamine (DB05381)	Argas reflexus	ALLERGEN ARG R 1	His_binding	10	SER A 28 ILE A 29 TYR A 37 VAL A 53 TYR A 67 ILE A 92 SER A 99 ASP A 110 VAL A 112 TRP A 121	HSM A1160
2X45_A_HSMA1161	2x45	HSM	Histamine (DB05381)	Argas reflexus	ALLERGEN ARG R 1	His_binding	8	VAL A 53 TYR A 69 ILE A 92 VAL A 94 ASP A 97 THR A 98 SER A 99 TRP A 121	HSM A1161
2X45_A_HSMA1162	2x45	HSM	Histamine (DB05381)	Argas reflexus	ALLERGEN ARG R 1	His_binding	7	LEU A 39 GLU A 47 THR A 51 ASP A 97 HIS A 114 GLU A 119 TRP A 121	HSM A1162
3BU1_A_HSMA301	3bu1	HSM	Histamine (DB05381)	Argas monolakensis	LIPOCALIN	His_binding	10	SER A 12 LEU A 13 TYR A 21 VAL A 37 TYR A 51 ILE A 76 SER A 83 ASP A 94 VAL A 96 TRP A 105	HSM A 301
3RXH_A_HSMA7	3rxh	HSM	Histamine (DB05381)	Bos taurus	CATIONIC TRYPSIN	Trypsin	11	ASP A 189 SER A 190 CYS A 191 GLN A 192 SER A 195 VAL A 209 SER A 210 TRP A 211 GLY A 212 GLY A 214 GLY A 222	HSM A 7
4XMF_A_HSMA202	4xmf	HSM	Histamine (DB05381)	Rhodnius prolixus	NITROPHORIN-7	Nitrophorin	6	ASP A 32 HIS A 60 LEU A 125 GLY A 133 ASP A 134 LEU A 135	HSM A 202
5RUS_A_HSMA201	5rus	HSM	Histamine (DB05381)	Severe acute respiratory syndrome coronavirus 2	NON-STRUCTURAL PROTEIN 3	Macro	7	ASP A 22 ILE A 23 VAL A 24 GLY A 48 VAL A 49 ALA A 52 PHE A 156	HSM A 201
6DYN_A_HSMA901	6dyn	HSM	Histamine (DB05381)	Drosophila melanogaster	EBONY	NA	10	PHE A 689 LEU A 695 GLU A 696 VAL A 760 LEU A 764 SER A 786 PHE A 787 THR A 825 THR A 826 THR A 828	HSM A 901
6FU4_A_HSMA401	6fu4	HSM	Histamine (DB05381)	Pseudomonas aeruginosa pao1	PROBABLE CHEMOTAXIS TRANSDUCER	NA	9	TYR A 126 TYR A 158 GLU A 170 GLU A 176 TYR A 189 TRP A 192 TYR A 208 ASP A 210 ASP A 239	HSM A 401
7A5V_A_HSMA5408	7a5v	HSM	Histamine (DB05381)	Homo sapiens; lama glama	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3	Neur_chan_LBD Neur_chan_memb	7	TYR A 97 GLU A 155 SER A 156 TYR A 157 PHE A 200 THR A 202 TYR A 205	HSM A5408
7DFL_R_HSMR900	7dfl	HSM	Histamine (DB05381)	Homo sapiens	HISTAMINE H1 RECEPTOR	7tm_1	11	ASP R 107 TYR R 108 SER R 111 THR R 112 TRP R 158 ASN R 198 TRP R 428 TYR R 431 PHE R 432 ILE R 454 TYR R 458	HSM R 900
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1AVN_A_HSMA264","1avn","HSM","Histamine (DB05381)","Homo sapiens","CARBONIC ANHYDRASE II","Carb_anhydrase",4,"ASN A  62;HIS A  64;ASN A  67;GLN A  92","HSM A 264\r"],["1IKE_A_HSMA190","1ike","HSM","Histamine (DB05381)","Rhodnius prolixus","NITROPHORIN 4","Nitrophorin",9,"ASP A  30;GLU A  32;HIS A  59;THR A 121;LEU A 123;LEU A 130;GLY A 131;ASP A 132;LEU A 133","HSM A 190\r"],["1JQD_A_HSMA600","1jqd","HSM","Histamine (DB05381)","Homo sapiens","HISTAMINE N-METHYLTRANSFERASE","Methyltransf_23",10,"PHE A  22;GLU A  28;GLN A 143;TYR A 146;VAL A 173;TRP A 179;TRP A 183;PHE A 243;ASN A 283;LEU A 285","HSM A 600\r"],["1KAR_A_HSMA502","1kar","HSM","Histamine (DB05381)","Escherichia coli","HISTIDINOL DEHYDROGENASE","Histidinol_dh",11,"LEU A 138;SER A 140;SER A 237;HIS A 262;GLU A 326;ASP A 360;TYR A 361;HIS A 367;GLU B 414;LEU B 416;HIS B 419","HSM A 502\r"],["1QFT_A_HSMA176","1qft","HSM","Histamine (DB05381)","Rhipicephalus appendiculatus","PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2)","His_binding",10,"SER A  20;LEU A  21;ASP A  24;TYR A  29;VAL A  51;PHE A  98;TYR A 100;ASP A 120;ILE A 122;TRP A 137","HSM A 176\r"],["1QFT_A_HSMA177","1qft","HSM","Histamine (DB05381)","Rhipicephalus appendiculatus","PROTEIN (FEMALE-SPECIFIC HISTAMINE BINDING PROTEIN 2)","His_binding",10,"TYR A  36;ASP A  39;VAL A  41;TRP A  42;GLU A  82;TYR A 100;PHE A 108;ASP A 110;VAL A 124;GLU A 135","HSM A 177\r"],["1U18_A_HSMA401","1u18","HSM","Histamine (DB05381)","Rhodnius prolixus","NITROPHORIN 1","Nitrophorin",7,"ASP A  31;GLU A  33;THR A 122;LEU A 124;LEU A 131;GLY A 132;LEU A 134","HSM A 401\r"],["2QEB_A_HSMA145","2qeb","HSM","Histamine (DB05381)","Anopheles gambiae","D7R4 PROTEIN","NA",11,"GLU A   7;ILE A  21;ARG A  22;TYR A  24;ILE A  36;VAL A  39;TYR A  94;PHE A 110;ASP A 111;GLU A 114;MET A 135","HSM A 145\r"],["2X45_A_HSMA1160","2x45","HSM","Histamine (DB05381)","Argas reflexus","ALLERGEN ARG R 1","His_binding",10,"SER A  28;ILE A  29;TYR A  37;VAL A  53;TYR A  67;ILE A  92;SER A  99;ASP A 110;VAL A 112;TRP A 121","HSM A1160\r"],["2X45_A_HSMA1161","2x45","HSM","Histamine (DB05381)","Argas reflexus","ALLERGEN ARG R 1","His_binding",8,"VAL A  53;TYR A  69;ILE A  92;VAL A  94;ASP A  97;THR A  98;SER A  99;TRP A 121","HSM A1161\r"],["2X45_A_HSMA1162","2x45","HSM","Histamine (DB05381)","Argas reflexus","ALLERGEN ARG R 1","His_binding",7,"LEU A  39;GLU A  47;THR A  51;ASP A  97;HIS A 114;GLU A 119;TRP A 121","HSM A1162\r"],["3BU1_A_HSMA301","3bu1","HSM","Histamine (DB05381)","Argas monolakensis","LIPOCALIN","His_binding",10,"SER A  12;LEU A  13;TYR A  21;VAL A  37;TYR A  51;ILE A  76;SER A  83;ASP A  94;VAL A  96;TRP A 105","HSM A 301\r"],["3RXH_A_HSMA7","3rxh","HSM","Histamine (DB05381)","Bos taurus","CATIONIC TRYPSIN","Trypsin",11,"ASP A 189;SER A 190;CYS A 191;GLN A 192;SER A 195;VAL A 209;SER A 210;TRP A 211;GLY A 212;GLY A 214;GLY A 222","HSM A   7\r"],["4XMF_A_HSMA202","4xmf","HSM","Histamine (DB05381)","Rhodnius prolixus","NITROPHORIN-7","Nitrophorin",6,"ASP A  32;HIS A  60;LEU A 125;GLY A 133;ASP A 134;LEU A 135","HSM A 202\r"],["5RUS_A_HSMA201","5rus","HSM","Histamine (DB05381)","Severe acute respiratory syndrome coronavirus 2","NON-STRUCTURAL PROTEIN 3","Macro",7,"ASP A  22;ILE A  23;VAL A  24;GLY A  48;VAL A  49;ALA A  52;PHE A 156","HSM A 201\r"],["6DYN_A_HSMA901","6dyn","HSM","Histamine (DB05381)","Drosophila melanogaster","EBONY","NA",10,"PHE A 689;LEU A 695;GLU A 696;VAL A 760;LEU A 764;SER A 786;PHE A 787;THR A 825;THR A 826;THR A 828","HSM A 901\r"],["6FU4_A_HSMA401","6fu4","HSM","Histamine (DB05381)","Pseudomonas aeruginosa pao1","PROBABLE CHEMOTAXIS TRANSDUCER","NA",9,"TYR A 126;TYR A 158;GLU A 170;GLU A 176;TYR A 189;TRP A 192;TYR A 208;ASP A 210;ASP A 239","HSM A 401\r"],["7A5V_A_HSMA5408","7a5v","HSM","Histamine (DB05381)","Homo sapiens;lama glama","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3","Neur_chan_LBD;Neur_chan_memb",7,"TYR A  97;GLU A 155;SER A 156;TYR A 157;PHE A 200;THR A 202;TYR A 205","HSM A5408\r"],["7DFL_R_HSMR900","7dfl","HSM","Histamine (DB05381)","Homo sapiens","HISTAMINE H1 RECEPTOR","7tm_1",11,"ASP R 107;TYR R 108;SER R 111;THR R 112;TRP R 158;ASN R 198;TRP R 428;TYR R 431;PHE R 432;ILE R 454;TYR R 458","HSM R 900\r"]]