Ligand ID: RB6

Drugbank ID:
Ceftobiprole
(DB04918)

Indication:
Ceftobiprole is a cephalosporin antibiotic used to treat both community and hospital-acquired pneumonia caused by susceptible bacteria.

LIST OF BINDING INTERFACES for query 'RB6'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4DKI_A_RB6A701	4dki	RB6	Ceftobiprole (DB04918)	Staphylococcus aureus	PENICILLIN-BINDING PROTEIN 2'	MecA_N PBP_dimer Transpeptidase	21	SER A 400 GLY A 402 SER A 403 LYS A 406 TYR A 446 SER A 462 ASN A 464 TYR A 519 GLY A 520 GLN A 521 HIS A 583 LYS A 597 SER A 598 GLY A 599 THR A 600 ALA A 601 GLU A 602 MET A 605 GLN A 613 MET A 641 ALA A 642	RB6 A 701		Details
5TXI_A_RB6A401	5txi	RB6	Ceftobiprole (DB04918)	Staphylococcus aureus	PENICILLIN BINDING PROTEIN 4	DUF1958 Peptidase_S11	16	ALA A  74 SER A  75 LEU A 115 SER A 139 GLY A 181 ALA A 182 GLU A 183 ARG A 186 PHE A 241 THR A 260 GLY A 261 SER A 262 SER A 263 ASP A 264 TYR A 268 TYR A 291	RB6 A 401		Details
6G88_A_RB6A700	6g88	RB6	Ceftobiprole (DB04918)	Enterococcus faecium	LOW AFFINITY PENICILLIN-BINDING PROTEIN 5 (PBP5)	MecA_N PBP_dimer Transpeptidase	19	GLY A 421 SER A 422 LYS A 425 THR A 463 ARG A 464 VAL A 465 SER A 466 TYR A 479 SER A 480 ASN A 482 TYR A 538 GLN A 540 THR A 603 LYS A 617 THR A 618 GLY A 619 THR A 620 ALA A 621 GLU A 622	RB6 A 700		Details
6VJE_A_RB6A601	6vje	RB6	Ceftobiprole (DB04918)	Pseudomonas aeruginosa	PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI	PBP_dimer Transpeptidase	23	GLU A 291 GLY A 293 SER A 294 LYS A 297 VAL A 333 SER A 349 ASN A 351 TYR A 407 GLY A 408 TYR A 409 LYS A 484 SER A 485 GLY A 486 THR A 487 ALA A 488 ARG A 489 TYR A 503 LYS A 529 ALA A 530 GLY A 531 TYR A 532 PHE A 533 GLY A 534	RB6 A 601		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4DKI_A_RB6A701","4dki","RB6","Ceftobiprole (DB04918)","Staphylococcus aureus","PENICILLIN-BINDING PROTEIN 2'","MecA_N;PBP_dimer;Transpeptidase",21,"SER A 400;GLY A 402;SER A 403;LYS A 406;TYR A 446;SER A 462;ASN A 464;TYR A 519;GLY A 520;GLN A 521;HIS A 583;LYS A 597;SER A 598;GLY A 599;THR A 600;ALA A 601;GLU A 602;MET A 605;GLN A 613;MET A 641;ALA A 642","RB6 A 701\r"],["5TXI_A_RB6A401","5txi","RB6","Ceftobiprole (DB04918)","Staphylococcus aureus","PENICILLIN BINDING PROTEIN 4","DUF1958;Peptidase_S11",16,"ALA A 74;SER A 75;LEU A 115;SER A 139;GLY A 181;ALA A 182;GLU A 183;ARG A 186;PHE A 241;THR A 260;GLY A 261;SER A 262;SER A 263;ASP A 264;TYR A 268;TYR A 291","RB6 A 401\r"],["6G88_A_RB6A700","6g88","RB6","Ceftobiprole (DB04918)","Enterococcus faecium","LOW AFFINITY PENICILLIN-BINDING PROTEIN 5 (PBP5)","MecA_N;PBP_dimer;Transpeptidase",19,"GLY A 421;SER A 422;LYS A 425;THR A 463;ARG A 464;VAL A 465;SER A 466;TYR A 479;SER A 480;ASN A 482;TYR A 538;GLN A 540;THR A 603;LYS A 617;THR A 618;GLY A 619;THR A 620;ALA A 621;GLU A 622","RB6 A 700\r"],["6VJE_A_RB6A601","6vje","RB6","Ceftobiprole (DB04918)","Pseudomonas aeruginosa","PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI","PBP_dimer;Transpeptidase",23,"GLU A 291;GLY A 293;SER A 294;LYS A 297;VAL A 333;SER A 349;ASN A 351;TYR A 407;GLY A 408;TYR A 409;LYS A 484;SER A 485;GLY A 486;THR A 487;ALA A 488;ARG A 489;TYR A 503;LYS A 529;ALA A 530;GLY A 531;TYR A 532;PHE A 533;GLY A 534","RB6 A 601\r"]]