Results: Ligand

Ligand ID: CE3

Drugbank ID:
Cefotaxime
(DB00493)

Indication:
Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections.

LIST OF BINDING INTERFACES for query 'DB00493'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4KOT_A_CE3A205	4kot	CE3	Cefotaxime (DB00493)	Pseudomonas aeruginosa	UNCHARACTERIZED PROTEIN	Acetyltransf_1	18	PHE A 27 TYR A 28 CYS A 29 TYR A 30 PRO A 31 ARG A 49 TYR A 68 LEU A 78 GLY A 79 ASN A 80 MET A 81 ILE A 115 SER A 116 PHE A 118 TYR A 128 ARG A 141 HIS A 142 LEU A 151	CE3 A 205
4PM5_A_CE3A301	4pm5	CE3	Cefotaxime (DB00493)	Klebsiella pneumoniae subsp. pneumoniae	BETA-LACTAMASE CTX-M-14	Beta-lactamase2	15	CYS A 69 GLY A 70 ASN A 104 TYR A 105 SER A 130 ASN A 132 PRO A 167 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238 ASP A 240	CE3 A 301
5NZY_A_CE3A1102	5nzy	CE3	Cefotaxime (DB00493)	Homo sapiens	DNA CROSS-LINK REPAIR 1A PROTEIN	DRMBL	9	ILE A 937 ASN A 938 PHE A 939 ARG A 960 THR A 962 GLN A 979 ILE A 986 TYR A 987 GLY A 988	CE3 A1102
5NZY_A_CE3A1103	5nzy	CE3	Cefotaxime (DB00493)	Homo sapiens	DNA CROSS-LINK REPAIR 1A PROTEIN	DRMBL	13	THR A 700 CYS A 701 PRO A 702 PHE A 703 TYR A 704 GLN A 718 ASP A 736 THR A1015 VAL A1016 ASN A1017 VAL A1018 GLY A1019 ARG A1024	CE3 A1103
6C79_A_CE3A301	6c79	CE3	Cefotaxime (DB00493)	Escherichia coli	BETA-LACTAMASE TOHO-1	Beta-lactamase2	17	CYS A 69 ALA A 70 LYS A 73 ASN A 104 TYR A 105 SER A 130 ASN A 132 PRO A 167 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238 ASP A 239 ASN A 272	CE3 A 301
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4KOT_A_CE3A205","4kot","CE3","Cefotaxime (DB00493)","Pseudomonas aeruginosa","UNCHARACTERIZED PROTEIN","Acetyltransf_1",18,"PHE A  27;TYR A  28;CYS A  29;TYR A  30;PRO A  31;ARG A  49;TYR A  68;LEU A  78;GLY A  79;ASN A  80;MET A  81;ILE A 115;SER A 116;PHE A 118;TYR A 128;ARG A 141;HIS A 142;LEU A 151","CE3 A 205\r"],["4PM5_A_CE3A301","4pm5","CE3","Cefotaxime (DB00493)","Klebsiella pneumoniae subsp. pneumoniae","BETA-LACTAMASE CTX-M-14","Beta-lactamase2",15,"CYS A  69;GLY A  70;ASN A 104;TYR A 105;SER A 130;ASN A 132;PRO A 167;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238;ASP A 240","CE3 A 301\r"],["5NZY_A_CE3A1102","5nzy","CE3","Cefotaxime (DB00493)","Homo sapiens","DNA CROSS-LINK REPAIR 1A PROTEIN","DRMBL",9,"ILE A 937;ASN A 938;PHE A 939;ARG A 960;THR A 962;GLN A 979;ILE A 986;TYR A 987;GLY A 988","CE3 A1102\r"],["5NZY_A_CE3A1103","5nzy","CE3","Cefotaxime (DB00493)","Homo sapiens","DNA CROSS-LINK REPAIR 1A PROTEIN","DRMBL",13,"THR A 700;CYS A 701;PRO A 702;PHE A 703;TYR A 704;GLN A 718;ASP A 736;THR A1015;VAL A1016;ASN A1017;VAL A1018;GLY A1019;ARG A1024","CE3 A1103\r"],["6C79_A_CE3A301","6c79","CE3","Cefotaxime (DB00493)","Escherichia coli","BETA-LACTAMASE TOHO-1","Beta-lactamase2",17,"CYS A  69;ALA A  70;LYS A  73;ASN A 104;TYR A 105;SER A 130;ASN A 132;PRO A 167;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238;ASP A 239;ASN A 272","CE3 A 301\r"]]