Ligand ID: NMY

Drugbank ID:
Framycetin
(DB00452)

Indication:
Framycetin is an aminoglycoside antibiotic used in various formulations and combinations with other agents to treat hemorrhoids, eye and ear infections, and to reduce nasal carriage of staphylococcus.

LIST OF BINDING INTERFACES for query 'DB00452'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2B0Q_A_NMYA305	2b0q	NMY	Framycetin (DB00452)	Enterococcus faecalis	AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE	APH	20	GLU A  24 MET A  26 SER A  27 SER A  99 GLU A 157 ASN A 158 TRP A 159 GLU A 160 ASP A 190 ASP A 193 SER A 194 ASN A 195 ASP A 208 ARG A 211 ARG A 226 GLU A 230 ASP A 231 ASP A 261 GLU A 262 PHE A 264	NMY A 305		Details
5DV4_A_NMYA601	5dv4	NMY	Framycetin (DB00452)	Homo sapiens	CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE	Exo_endo_phos	21	ASN A 195 TYR A 201 LEU A 206 TYR A 207 GLU A 240 ASN A 325 HIS A 360 MET A 361 HIS A 362 TRP A 363 PRO A 365 LYS A 371 ASP A 410 ASN A 412 SER A 413 LEU A 414 ASN A 479 PHE A 484 ILE A 488 ASP A 528 HIS A 529	NMY A 601		Details
5IQE_A_NMYA600	5iqe	NMY	Framycetin (DB00452)	Staphylococcus aureus	BIFUNCTIONAL AAC/APH	APH	13	ASP A 374 SER A 376 ASN A 378 HIS A 379 ASP A 396 TYR A 408 GLU A 411 SER A 413 GLU A 415 GLU A 416 GLU A 445 TYR A 448 GLU A 451	NMY A 600		Details
6MB5_A_NMYA301	6mb5	NMY	Framycetin (DB00452)	Pseudomonas aeruginosa	AAC(3)-IIIB PROTEIN	Antibiotic_NAT	14	TYR A  65 ASP A  67 ASN A 104 GLY A 124 TYR A 147 ASP A 171 THR A 172 HIS A 177 ASP A 212 THR A 213 GLY A 214 ASP A 215 GLU A 223 PHE A 226	NMY A 301		Details
6UN8_A_NMYA300	6un8	NMY	Framycetin (DB00452)	Staphylococcus aureus	AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE	KNTase_C	14	TYR A  37 GLU A  52 GLU A  63 GLU A  67 GLU A  76 ASN A  78 ASP A  80 ILE A  84 LEU A  85 TYR A  88 GLN A 102 GLU B 141 GLU B 142 GLU B 145	NMY A 300		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2B0Q_A_NMYA305","2b0q","NMY","Framycetin (DB00452)","Enterococcus faecalis","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE","APH",20,"GLU A 24;MET A 26;SER A 27;SER A 99;GLU A 157;ASN A 158;TRP A 159;GLU A 160;ASP A 190;ASP A 193;SER A 194;ASN A 195;ASP A 208;ARG A 211;ARG A 226;GLU A 230;ASP A 231;ASP A 261;GLU A 262;PHE A 264","NMY A 305\r"],["5DV4_A_NMYA601","5dv4","NMY","Framycetin (DB00452)","Homo sapiens","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","Exo_endo_phos",21,"ASN A 195;TYR A 201;LEU A 206;TYR A 207;GLU A 240;ASN A 325;HIS A 360;MET A 361;HIS A 362;TRP A 363;PRO A 365;LYS A 371;ASP A 410;ASN A 412;SER A 413;LEU A 414;ASN A 479;PHE A 484;ILE A 488;ASP A 528;HIS A 529","NMY A 601\r"],["5IQE_A_NMYA600","5iqe","NMY","Framycetin (DB00452)","Staphylococcus aureus","BIFUNCTIONAL AAC\/APH","APH",13,"ASP A 374;SER A 376;ASN A 378;HIS A 379;ASP A 396;TYR A 408;GLU A 411;SER A 413;GLU A 415;GLU A 416;GLU A 445;TYR A 448;GLU A 451","NMY A 600\r"],["6MB5_A_NMYA301","6mb5","NMY","Framycetin (DB00452)","Pseudomonas aeruginosa","AAC(3)-IIIB PROTEIN","Antibiotic_NAT",14,"TYR A 65;ASP A 67;ASN A 104;GLY A 124;TYR A 147;ASP A 171;THR A 172;HIS A 177;ASP A 212;THR A 213;GLY A 214;ASP A 215;GLU A 223;PHE A 226","NMY A 301\r"],["6UN8_A_NMYA300","6un8","NMY","Framycetin (DB00452)","Staphylococcus aureus","AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE","KNTase_C",14,"TYR A 37;GLU A 52;GLU A 63;GLU A 67;GLU A 76;ASN A 78;ASP A 80;ILE A 84;LEU A 85;TYR A 88;GLN A 102;GLU B 141;GLU B 142;GLU B 145","NMY A 300\r"]]