Results: Ligand

Ligand ID: PPF

Drugbank ID:
Foscarnet
(DB00529)

Indication:
Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections.

LIST OF BINDING INTERFACES for query 'DB00529'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1EI6_A_PPFA410	1ei6	PPF	Foscarnet (DB00529)	Pseudomonas fluorescens	PHOSPHONOACETATE HYDROLASE	Phosphodiest	12	ASP A 25 PHE A 63 THR A 64 LYS A 126 THR A 201 ASP A 202 HIS A 206 ASP A 241 HIS A 242 ILE A 278 THR A 279 HIS A 368	PPF A 410
1NKI_A_PPFA5001	1nki	PPF	Foscarnet (DB00529)	Pseudomonas aeruginosa	PROBABLE FOSFOMYCIN RESISTANCE PROTEIN	Glyoxalase	11	HIS B 7 THR B 9 TYR B 39 CYS B 48 TYR A 62 HIS A 64 LYS A 90 SER A 94 TYR A 100 GLU A 110 ARG A 119	PPF A5001
2IT4_A_PPFA500	2it4	PPF	Foscarnet (DB00529)	Homo sapiens	CARBONIC ANHYDRASE 1	Carb_anhydrase	12	GLN A 92 HIS A 94 HIS A 96 HIS A 119 ALA A 121 VAL A 143 SER A 197 LEU A 198 THR A 199 HIS A 200 VAL A 207 TRP A 209	PPF A 500
2RK8_A_PPFA3969	2rk8	PPF	Foscarnet (DB00529)	Rattus norvegicus	PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP]	PEPCK_GTP PEPCK_N	12	ARG A 87 TYR A 235 LYS A 243 LYS A 244 HIS A 264 SER A 286 ALA A 287 ASP A 311 PHE A 333 ARG A 405 ALA A 467 PHE A 485	PPF A3969
3KD5_E_PPFE914	3kd5	PPF	Foscarnet (DB00529)	Enterobacteria phage rb69; synthetic construct	DNA POLYMERASE	DNA_pol_B DNA_pol_B_exo1	9	ASP E 411 LEU E 412 THR E 413 SER E 414 LEU E 415 ARG E 482 LYS E 560 ASN E 564 ASP E 623	PPF E 914
3T01_A_PPFA503	3t01	PPF	Foscarnet (DB00529)	Sinorhizobium meliloti	PHOSPHONOACETATE HYDROLASE	Phosphodiest	9	ASP A 29 PHE A 67 THR A 68 ASN A 69 ASN A 89 ASP A 211 HIS A 215 ILE A 287 HIS A 377	PPF A 503
4MV7_A_PPFA501	4mv7	PPF	Foscarnet (DB00529)	Haemophilus influenzae	BIOTIN CARBOXYLASE	Biotin_carb_C Biotin_carb_N CPSase_L_D2	9	TYR A 82 LYS A 238 GLU A 276 ASN A 290 ARG A 292 GLN A 294 VAL A 295 GLU A 296 ARG A 338	PPF A 501
5HP1_A_PPFA602	5hp1	PPF	Foscarnet (DB00529)	Human immunodeficiency virus type 1 group m subtype b (isolate bh10); synthetic construct	HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT	RVT_1 RVT_connect RVT_thumb	8	LYS A 65 ARG A 72 ASP A 110 VAL A 111 GLY A 112 ASP A 113 ALA A 114 ASP A 185	PPF A 602
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1EI6_A_PPFA410","1ei6","PPF","Foscarnet (DB00529)","Pseudomonas fluorescens","PHOSPHONOACETATE HYDROLASE","Phosphodiest",12,"ASP A  25;PHE A  63;THR A  64;LYS A 126;THR A 201;ASP A 202;HIS A 206;ASP A 241;HIS A 242;ILE A 278;THR A 279;HIS A 368","PPF A 410\r"],["1NKI_A_PPFA5001","1nki","PPF","Foscarnet (DB00529)","Pseudomonas aeruginosa","PROBABLE FOSFOMYCIN RESISTANCE PROTEIN","Glyoxalase",11,"HIS B   7;THR B   9;TYR B  39;CYS B  48;TYR A  62;HIS A  64;LYS A  90;SER A  94;TYR A 100;GLU A 110;ARG A 119","PPF A5001\r"],["2IT4_A_PPFA500","2it4","PPF","Foscarnet (DB00529)","Homo sapiens","CARBONIC ANHYDRASE 1","Carb_anhydrase",12,"GLN A  92;HIS A  94;HIS A  96;HIS A 119;ALA A 121;VAL A 143;SER A 197;LEU A 198;THR A 199;HIS A 200;VAL A 207;TRP A 209","PPF A 500\r"],["2RK8_A_PPFA3969","2rk8","PPF","Foscarnet (DB00529)","Rattus norvegicus","PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP]","PEPCK_GTP;PEPCK_N",12,"ARG A  87;TYR A 235;LYS A 243;LYS A 244;HIS A 264;SER A 286;ALA A 287;ASP A 311;PHE A 333;ARG A 405;ALA A 467;PHE A 485","PPF A3969\r"],["3KD5_E_PPFE914","3kd5","PPF","Foscarnet (DB00529)","Enterobacteria phage rb69;synthetic construct","DNA POLYMERASE","DNA_pol_B;DNA_pol_B_exo1",9,"ASP E 411;LEU E 412;THR E 413;SER E 414;LEU E 415;ARG E 482;LYS E 560;ASN E 564;ASP E 623","PPF E 914\r"],["3T01_A_PPFA503","3t01","PPF","Foscarnet (DB00529)","Sinorhizobium meliloti","PHOSPHONOACETATE HYDROLASE","Phosphodiest",9,"ASP A  29;PHE A  67;THR A  68;ASN A  69;ASN A  89;ASP A 211;HIS A 215;ILE A 287;HIS A 377","PPF A 503\r"],["4MV7_A_PPFA501","4mv7","PPF","Foscarnet (DB00529)","Haemophilus influenzae","BIOTIN CARBOXYLASE","Biotin_carb_C;Biotin_carb_N;CPSase_L_D2",9,"TYR A  82;LYS A 238;GLU A 276;ASN A 290;ARG A 292;GLN A 294;VAL A 295;GLU A 296;ARG A 338","PPF A 501\r"],["5HP1_A_PPFA602","5hp1","PPF","Foscarnet (DB00529)","Human immunodeficiency virus type 1 group m subtype b (isolate bh10);synthetic construct","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","RVT_1;RVT_connect;RVT_thumb",8,"LYS A  65;ARG A  72;ASP A 110;VAL A 111;GLY A 112;ASP A 113;ALA A 114;ASP A 185","PPF A 602\r"]]