Results: Ligand

Ligand ID: 1RG

Drugbank ID:
Ertapenem
(DB00303)

Indication:
Ertapenem is a carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.

LIST OF BINDING INTERFACES for query 'DB00303'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3M6B_A_1RGA308	3m6b	1RG	Ertapenem (DB00303)	Mycobacterium tuberculosis	BETA-LACTAMASE	Beta-lactamase2	17	CYS A 83 SER A 84 LYS A 87 ILE A 117 SER A 142 GLY A 144 GLU A 182 ASN A 186 THR A 232 ARG A 236 LYS A 250 THR A 251 GLY A 252 THR A 253 GLU A 289 PRO A 290 GLU A 292	1RG A 308
3M6B_A_1RGA309	3m6b	1RG	Ertapenem (DB00303)	Mycobacterium tuberculosis	BETA-LACTAMASE	Beta-lactamase2	5	GLU A 289 PRO A 290 ARG A 291 GLU A 292 ALA A 293	1RG A 309
3ZGP_A_1RGA130	3zgp	1RG	Ertapenem (DB00303)	Enterococcus faecium	ERFK/YBIS/YCFS/YNHG	YkuD	30	LYS A 372 THR A 374 THR A 375 PRO A 376 LEU A 393 LYS A 394 GLY A 395 THR A 396 ASN A 397 ASP A 398 ASP A 399 GLY A 400 THR A 401 TYR A 403 SER A 405 TRP A 410 ILE A 413 ASP A 414 TRP A 415 THR A 416 GLY A 417 VAL A 418 GLY A 419 HIS A 421 TRP A 425 SER A 439 HIS A 440 GLY A 441 CYS A 442 ASN A 444	1RG A 130
4GCS_A_1RGA401	4gcs	1RG	Ertapenem (DB00303)	Escherichia coli	OUTER MEMBRANE PROTEIN F	Porin_1	6	THR A 165 ALA A 166 ARG A 167 ARG A 168 GLN A 203 SER A 248	1RG A 401
4QU3_A_1RGA501	4qu3	1RG	Ertapenem (DB00303)	Pseudomonas aeruginosa	BETA-LACTAMASE GES-2	Beta-lactamase2	17	CYS A 63 SER A 64 LYS A 67 TRP A 99 SER A 125 ASN A 127 GLU A 161 ASN A 165 GLN A 210 THR A 211 ALA A 214 LYS A 229 THR A 230 GLY A 231 THR A 232 ARG A 238 ASP A 268	1RG A 501
6P99_A_1RGA501	6p99	1RG	Ertapenem (DB00303)	Klebsiella pneumoniae	BETA-LACTAMASE	Transpeptidase	17	ALA A 69 SER A 70 ILE A 102 TRP A 105 TYR A 117 SER A 118 VAL A 120 LEU A 158 LYS A 208 THR A 209 GLY A 210 TYR A 211 ASP A 245 LEU A 247 GLY A 248 ARG A 250 GLN A 251	1RG A 501
6SKR_A_1RGA301	6skr	1RG	Ertapenem (DB00303)	Escherichia coli	BETA-LACTAMASE	Transpeptidase	19	ALA A 66 SER A 67 THR A 68 MET A 99 GLN A 101 TRP A 102 SER A 115 ALA A 116 VAL A 117 LEU A 155 LYS A 205 THR A 206 GLY A 207 PHE A 208 GLU A 244 LEU A 247 PRO A 248 ARG A 250 LYS A 251	1RG A 301
7KGM_A_1RGA801	7kgm	1RG	Ertapenem (DB00303)	Citrobacter rodentium (strain icc168)	PUTATIVE EXPORTED PROTEIN	PG_binding_1 Scaffold YkuD	10	TRP A 434 PRO A 437 LEU A 440 ALA A 514 TYR A 516 HIS A 518 SER A 534 SER A 535 GLY A 536 CYS A 537	1RG A 801
7KGN_A_1RGA901	7kgn	1RG	Ertapenem (DB00303)	Salmonella enterica	L,D-TRANSPEPTIDASE	PG_binding_1 Scaffold YkuD	8	TRP A 423 PRO A 426 THR A 428 LEU A 429 TYR A 505 SER A 524 GLY A 525 CYS A 526	1RG A 901
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3M6B_A_1RGA308","3m6b","1RG","Ertapenem (DB00303)","Mycobacterium tuberculosis","BETA-LACTAMASE","Beta-lactamase2",17,"CYS A  83;SER A  84;LYS A  87;ILE A 117;SER A 142;GLY A 144;GLU A 182;ASN A 186;THR A 232;ARG A 236;LYS A 250;THR A 251;GLY A 252;THR A 253;GLU A 289;PRO A 290;GLU A 292","1RG A 308\r"],["3M6B_A_1RGA309","3m6b","1RG","Ertapenem (DB00303)","Mycobacterium tuberculosis","BETA-LACTAMASE","Beta-lactamase2",5,"GLU A 289;PRO A 290;ARG A 291;GLU A 292;ALA A 293","1RG A 309\r"],["3ZGP_A_1RGA130","3zgp","1RG","Ertapenem (DB00303)","Enterococcus faecium","ERFK\/YBIS\/YCFS\/YNHG","YkuD",30,"LYS A 372;THR A 374;THR A 375;PRO A 376;LEU A 393;LYS A 394;GLY A 395;THR A 396;ASN A 397;ASP A 398;ASP A 399;GLY A 400;THR A 401;TYR A 403;SER A 405;TRP A 410;ILE A 413;ASP A 414;TRP A 415;THR A 416;GLY A 417;VAL A 418;GLY A 419;HIS A 421;TRP A 425;SER A 439;HIS A 440;GLY A 441;CYS A 442;ASN A 444","1RG A 130\r"],["4GCS_A_1RGA401","4gcs","1RG","Ertapenem (DB00303)","Escherichia coli","OUTER MEMBRANE PROTEIN F","Porin_1",6,"THR A 165;ALA A 166;ARG A 167;ARG A 168;GLN A 203;SER A 248","1RG A 401\r"],["4QU3_A_1RGA501","4qu3","1RG","Ertapenem (DB00303)","Pseudomonas aeruginosa","BETA-LACTAMASE GES-2","Beta-lactamase2",17,"CYS A  63;SER A  64;LYS A  67;TRP A  99;SER A 125;ASN A 127;GLU A 161;ASN A 165;GLN A 210;THR A 211;ALA A 214;LYS A 229;THR A 230;GLY A 231;THR A 232;ARG A 238;ASP A 268","1RG A 501\r"],["6P99_A_1RGA501","6p99","1RG","Ertapenem (DB00303)","Klebsiella pneumoniae","BETA-LACTAMASE","Transpeptidase",17,"ALA A  69;SER A  70;ILE A 102;TRP A 105;TYR A 117;SER A 118;VAL A 120;LEU A 158;LYS A 208;THR A 209;GLY A 210;TYR A 211;ASP A 245;LEU A 247;GLY A 248;ARG A 250;GLN A 251","1RG A 501\r"],["6SKR_A_1RGA301","6skr","1RG","Ertapenem (DB00303)","Escherichia coli","BETA-LACTAMASE","Transpeptidase",19,"ALA A  66;SER A  67;THR A  68;MET A  99;GLN A 101;TRP A 102;SER A 115;ALA A 116;VAL A 117;LEU A 155;LYS A 205;THR A 206;GLY A 207;PHE A 208;GLU A 244;LEU A 247;PRO A 248;ARG A 250;LYS A 251","1RG A 301\r"],["7KGM_A_1RGA801","7kgm","1RG","Ertapenem (DB00303)","Citrobacter rodentium (strain icc168)","PUTATIVE EXPORTED PROTEIN","PG_binding_1;Scaffold;YkuD",10,"TRP A 434;PRO A 437;LEU A 440;ALA A 514;TYR A 516;HIS A 518;SER A 534;SER A 535;GLY A 536;CYS A 537","1RG A 801\r"],["7KGN_A_1RGA901","7kgn","1RG","Ertapenem (DB00303)","Salmonella enterica","L,D-TRANSPEPTIDASE","PG_binding_1;Scaffold;YkuD",8,"TRP A 423;PRO A 426;THR A 428;LEU A 429;TYR A 505;SER A 524;GLY A 525;CYS A 526","1RG A 901\r"]]