Ligand ID: PAR

Drugbank ID:
Paromomycin
(DB01421)

Indication:
Paromomycin is an aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.

LIST OF BINDING INTERFACES for query 'DB01421'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2VQY_A_PARA1201	2vqy	PAR	Paromomycin (DB01421)	Escherichia coli	AAC(6')-IB	Acetyltransf_8	18	TRP A  48 TRP A  49 GLY A  50 GLY A  51 GLN A  64 TYR A  65 LEU A  70 GLU A  73 VAL A  75 TYR A  89 GLN A  91 TYR A  93 SER A  98 TRP A 102 TRP A 103 ASP A 115 ASP A 152 ASP A 179	PAR A1201		Details
4QB9_A_PARA500	4qb9	PAR	Paromomycin (DB01421)	Mycobacterium smegmatis	ENHANCED INTRACELLULAR SURVIVAL PROTEIN	Acetyltransf_17 Acetyltransf_9 SCP2_2	18	PHE A  26 ILE A  82 SER A  83 PHE A  84 VAL A  85 LEU A 118 THR A 119 ALA A 120 SER A 121 TYR A 126 GLU A 137 VAL A 237 ASP A 290 ASP A 291 GLY A 399 TYR A 400 GLY A 401 PHE A 402	PAR A 500		Details
6MB7_A_PARA900	6mb7	PAR	Paromomycin (DB01421)	Pseudomonas aeruginosa	AAC(3)-IIIB PROTEIN	Antibiotic_NAT	14	TYR A  65 ASP A  67 ASP A 103 ASN A 104 GLY A 124 TYR A 147 ASP A 171 THR A 172 HIS A 177 ASP A 212 THR A 213 GLY A 214 ASP A 215 GLU A 223	PAR A 900		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2VQY_A_PARA1201","2vqy","PAR","Paromomycin (DB01421)","Escherichia coli","AAC(6')-IB","Acetyltransf_8",18,"TRP A 48;TRP A 49;GLY A 50;GLY A 51;GLN A 64;TYR A 65;LEU A 70;GLU A 73;VAL A 75;TYR A 89;GLN A 91;TYR A 93;SER A 98;TRP A 102;TRP A 103;ASP A 115;ASP A 152;ASP A 179","PAR A1201\r"],["4QB9_A_PARA500","4qb9","PAR","Paromomycin (DB01421)","Mycobacterium smegmatis","ENHANCED INTRACELLULAR SURVIVAL PROTEIN","Acetyltransf_17;Acetyltransf_9;SCP2_2",18,"PHE A 26;ILE A 82;SER A 83;PHE A 84;VAL A 85;LEU A 118;THR A 119;ALA A 120;SER A 121;TYR A 126;GLU A 137;VAL A 237;ASP A 290;ASP A 291;GLY A 399;TYR A 400;GLY A 401;PHE A 402","PAR A 500\r"],["6MB7_A_PARA900","6mb7","PAR","Paromomycin (DB01421)","Pseudomonas aeruginosa","AAC(3)-IIIB PROTEIN","Antibiotic_NAT",14,"TYR A 65;ASP A 67;ASP A 103;ASN A 104;GLY A 124;TYR A 147;ASP A 171;THR A 172;HIS A 177;ASP A 212;THR A 213;GLY A 214;ASP A 215;GLU A 223","PAR A 900\r"]]