LIST OF BINDING INTERFACES for query 'TRANSPORTER' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details
1u7g NH3Ammonia
(DB11118)
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium...PROBABLE AMMONIUM TRANSPORTER
(Escherichia coli)
NA
2q6h CXXClomipramine
(DB01242)
Clomipramine is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.TRANSPORTER
(Aquifex aeolicus)
SNF
2q72 IXXImipramine
(DB00458)
Imipramine is a tricyclic antidepressant indicated for the treatment of depression and to reduce childhood enuresis.TRANSPORTER
(Aquifex aeolicus)
SNF
2qb4 DSMDesipramine
(DB01151)
Desipramine is a tricyclic antidepressant used in the treatment of depression.TRANSPORTER
(Aquifex aeolicus)
SNF
2rin ACHAcetylcholine
(DB03128)
Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN
(Rhizobium meliloti)
OpuAC
3d6y BERBerberine
(DB04115)
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal...MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR
(Bacillus subtilis;
synthetic construct
)
GyrI-like
MerR
3gwu SRESertraline
(DB01104)
Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.TRANSPORTER
(Aquifex aeolicus)
SNF
3ip9 ABUGamma-aminobutyric acid
(DB02530)
The most common inhibitory neurotransmitter in the central nervous system.ABC TRANSPORTER, SUBSTRATE BINDING PROTEIN (AMINO ACID)
(Agrobacterium tumefaciens)
Peripla_BP_6
3q5p TACTetracycline
(DB00759)
Tetracycline is an antibiotic used to treat a wide variety of susceptible infections.MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR
(Bacillus subtilis;
synthetic construct
)
GyrI-like
MerR
3q5r KANKanamycin
(DB01172)
Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR
(Bacillus subtilis;
synthetic construct
)
GyrI-like
MerR
3q5s ACHAcetylcholine
(DB03128)
Acetylcholine is a parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR
(Bacillus subtilis;
synthetic construct
)
GyrI-like
MerR
4euo ABUGamma-aminobutyric acid
(DB02530)
The most common inhibitory neurotransmitter in the central nervous system.ABC TRANSPORTER, SUBSTRATE BINDING PROTEIN (POLYAMINE)
(Agrobacterium tumefaciens)
SBP_bac_8
4irx INSInositol
(DB13178)
Inositol is an ingredient found in a variety of nutritional products.SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN
(Caulobacter crescentus)
Peripla_BP_4
4m48 21BNortriptyline
(DB00540)
Nortriptyline is a tricyclic antidepressant used in the treatment of depression.TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
4mm4 8PRParoxetine
(DB00715)
Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.TRANSPORTER
(Aquifex aeolicus)
SNF
4mm9 FVXFluvoxamine
(DB00176)
Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.TRANSPORTER
(Aquifex aeolicus)
SNF
4mmc 29JDesvenlafaxine
(DB06700)
Desvenlafaxine is an antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.TRANSPORTER
(Aquifex aeolicus)
SNF
4mmd 29EDuloxetine
(DB00476)
Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.TRANSPORTER
(Aquifex aeolicus)
SNF
4mme 29QMazindol
(DB00579)
Mazindol is a sympathomimetic used to treat obesity in combination with lifestyle modifications.TRANSPORTER
(Aquifex aeolicus)
SNF
4o8m 2Q2Gluconic acid
(DB13180)
Gluconic Acid is an electrolyte supplement used in total parenteral nutrition.TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT
(Actinobacillus succinogenes)
DctP
4ru1 INSInositol
(DB13178)
Inositol is an ingredient found in a variety of nutritional products.MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY
(Acidothermus cellulolyticus)
Peripla_BP_4
4rxm INSInositol
(DB13178)
Inositol is an ingredient found in a variety of nutritional products.POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN
(Mannheimia haemolytica)
NA
4xnx 41XReboxetine
(DB00234)
Reboxetine is a drug used for the acute treatment of major depression and for maintenance therapy of depression.TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
4xp1 LDPDopamine
(DB00988)
Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.DOPAMINE TRANSPORTER, ISOFORM B
(Drosophila melanogaster;
mus musculus
)
SNF
4xp6 B40Metamfetamine
(DB01577)
Metamfetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
4xp9 1WEDextroamphetamine
(DB01576)
Dextroamphetamine is a sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
4yo7 INSInositol
(DB13178)
Inositol is an ingredient found in a variety of nutritional products.SUGAR ABC TRANSPORTER (SUGAR-BINDING PROTEIN)
(Bacillus halodurans)
Peripla_BP_4
5hko 62WMannitol
(DB00742)
Mannitol is a sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.ABC TRANSPORTER, CARBOHYDRATE UPTAKE TRANSPORTER-2 (CUT2) FAMILY, PERIPLASMIC SUGAR-BINDING PROTEIN
(Mycobacterium smegmatis (strain atcc 700084 / mc(2)155))
Peripla_BP_4
5i6x 8PRParoxetine
(DB00715)
Paroxetine is a selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.SODIUM-DEPENDENT SEROTONIN TRANSPORTER
(Homo sapiens;
mus musculus
)
SNF
5i71 68PEscitalopram
(DB01175)
Escitalopram is a selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).SODIUM-DEPENDENT SEROTONIN TRANSPORTER
(Homo sapiens;
mus musculus
)
SNF
5i73 ACAAminocaproic acid
(DB00513)
Aminocaproic acid is an antifibrinolytic agent used to induce clotting postoperatively.SODIUM-DEPENDENT SEROTONIN TRANSPORTER
(Homo sapiens;
mus musculus
)
SNF
5yk2 ERYErythromycin
(DB00199)
Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections.PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER
(Mycobacterium tuberculosis (strain atcc 25618 / h37rv))
ABC1
6awo SRESertraline
(DB01104)
Sertraline is a selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.SODIUM-DEPENDENT SEROTONIN TRANSPORTER
(Homo sapiens;
mus musculus
)
SNF
6awp FVXFluvoxamine
(DB00176)
Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.SODIUM-DEPENDENT SEROTONIN TRANSPORTER
(Homo sapiens;
mus musculus
)
SNF
6gz9 TXCValaciclovir
(DB00577)
Valaciclovir is an guanine nucleoside antiviral used to treat herpes exacerbations.PEPTIDE ABC TRANSPORTER PERMEASE
(Staphylococcus hominis)
PTR2
6hzp FVTAminolevulinic acid
(DB00855)
Aminolevulinic acid is a porphyrin precursor used to treat actinic keratosis of the face, scalp, and upper extremities, as well as to visualize a glioma.PEPTIDE ABC TRANSPORTER PERMEASE
(Staphylococcus hominis)
PTR2
6m38 29EDuloxetine
(DB00476)
Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.SODIUM-DEPENDENT DOPAMINE TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
6m3z F0FMilnacipran
(DB04896)
Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.SODIUM-DEPENDENT DOPAMINE TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
6m47 F1UTramadol
(DB00193)
Tramadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.SODIUM-DEPENDENT DOPAMINE TRANSPORTER
(Drosophila melanogaster;
mus musculus
)
SNF
6r4l ERGErgosterol
(DB04038)
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS...NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1-RELATED PROTEIN 1
(Saccharomyces cerevisiae (strain atcc 204508 / s288c))
NPC1_N
Patched
6vkt ERYErythromycin
(DB00199)
Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections.EFFLUX PUMP MEMBRANE TRANSPORTER
(Neisseria gonorrhoeae)
ACR_tran
6vrz CLMChloramphenicol
(DB00446)
Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.MULTIDRUG TRANSPORTER MDFA
(Escherichia coli)
MFS_1
6vxh STIImatinib
(DB00619)
Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.BROAD SUBSTRATE SPECIFICITY ATP-BINDING CASSETTE TRANSPORTER ABCG2
(Homo sapiens)
ABC2_membrane
ABC2_membrane_7
ABC_tran
7bcr 2Q2Gluconic acid
(DB13180)
Gluconic Acid is an electrolyte supplement used in total parenteral nutrition.PUTATIVE TRAP TRANSPORTER SOLUTE RECEPTOR DCTP
(Advenella mimigardefordensis dpn7)
DctP
7m4p YQMEravacycline
(DB12329)
Eravacycline is a tetracycline antibiotic used to treat complicated intra-abdominal infections.EFFLUX PUMP MEMBRANE TRANSPORTER
(Acinetobacter baumannii)
ACR_tran
PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details