Results: Ligand

Ligand ID: ERG

Drugbank ID:
Ergosterol
(DB04038)

Indication:
A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS...

LIST OF BINDING INTERFACES for query 'DB04038'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1BXM_A_ERGA99	1bxm	ERG	Ergosterol (DB04038)	Phytophthora cryptogea	BETA-CRYPTOGEIN	Elicitin	25	TYR A 12 LEU A 15 VAL A 16 ILE A 18 LEU A 19 PHE A 24 TYR A 33 MET A 35 LEU A 36 LEU A 41 PRO A 42 TYR A 47 MET A 50 MET A 59 ILE A 60 ILE A 63 VAL A 75 PRO A 76 THR A 77 LEU A 80 LEU A 82 VAL A 84 TYR A 87 ALA A 88 PHE A 91	ERG A 99
1ZHZ_A_ERGA1001	1zhz	ERG	Ergosterol (DB04038)	Saccharomyces cerevisiae	KES1 PROTEIN	Oxysterol_BP	25	TRP A 10 PHE A 13 LEU A 24 LEU A 27 ILE A 33 LEU A 39 PHE A 42 TRP A 46 GLN A 96 TYR A 97 ARG A 100 GLU A 107 LYS A 108 LYS A 109 PRO A 110 ASN A 165 ILE A 167 LEU A 177 VAL A 179 GLN A 181 LEU A 201 ILE A 203 ILE A 206 PRO A 211 VAL A 213	ERG A1001
2AIB_A_ERGA475	2aib	ERG	Ergosterol (DB04038)	Phytophthora cinnamomi	BETA-ELICITIN CINNAMOMIN	Elicitin	27	TYR A 12 LEU A 15 VAL A 16 ILE A 18 LEU A 19 LEU B 19 PHE A 24 TYR A 33 MET A 35 LEU A 36 LEU A 41 PRO A 42 TYR A 47 MET A 50 MET A 59 ILE A 60 ILE A 63 VAL A 75 PRO A 76 THR B 77 THR A 77 LEU A 80 LEU A 82 VAL A 84 TYR A 87 ALA A 88 PHE A 91	ERG A 475
5H2D_A_ERGA1301	5h2d	ERG	Ergosterol (DB04038)	Kluyveromyces lactis	KLLA0C04147P	Oxysterol_BP	24	LEU A 847 LEU A 851 MET A 859 LEU A 864 PHE A 868 LEU A 874 ARG A 877 VAL A 878 ASP A 881 TYR A 912 THR A 915 ARG A 918 VAL A 919 ALA A 920 LYS A 921 PRO A 922 VAL A 971 PHE A 980 PHE A 982 HIS A 984 LYS A1007 ASN A1010 VAL A1012 VAL A1022	ERG A1301
5YS0_A_ERGA1301	5ys0	ERG	Ergosterol (DB04038)	Saccharomyces cerevisiae (strain atcc 204508 / s288c)	MEMBRANE-ANCHORED LIPID-BINDING PROTEIN YSP2	VASt	20	TYR A1115 LYS A1117 LEU A1119 ASN A1121 GLY A1124 THR A1128 CYS A1130 GLN A1149 VAL A1151 SER A1153 VAL A1156 PRO A1157 PHE A1162 VAL A1164 THR A1197 GLY A1201 SER A1202 GLY A1205 GLN A1206 SER A1209	ERG A1301
6CAY_A_ERGA1101	6cay	ERG	Ergosterol (DB04038)	Saccharomyces cerevisiae	STEROL-BINDING PROTEIN	VASt	24	TYR A 908 LYS A 910 LEU A 912 ILE A 916 GLY A 917 PRO A 918 THR A 921 CYS A 923 ILE A 925 SER A 942 THR A 944 ASN A 946 VAL A 949 PRO A 950 PHE A 955 VAL A 957 THR A 959 PHE A 961 ILE A 991 GLY A 994 THR A 995 GLY A 998 VAL A 999 THR A1002	ERG A1101
6R4L_A_ERGA1201	6r4l	ERG	Ergosterol (DB04038)	Saccharomyces cerevisiae (strain atcc 204508 / s288c)	NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1-RELATED PROTEIN 1	NPC1_N Patched	17	PHE A 391 TYR A 392 THR A 394 GLN A 396 GLU A 450 GLN A 486 LEU A 492 LEU A 510 VAL A 799 GLY A 800 PRO A 801 PRO A 802 TYR A 804 ARG A 950 SER A 985 PRO A 986 PHE A 987	ERG A1201
6R4N_A_ERGA302	6r4n	ERG	Ergosterol (DB04038)	Saccharomyces cerevisiae (strain atcc 204508 / s288c)	PHOSPHATIDYLGLYCEROL/PHOSPHATIDYLINOSITOL TRANSFER PROTEIN	E1_DerP2_DerF2	8	PRO A 67 LEU A 73 VAL A 95 LEU A 102 VAL A 142 TYR A 147 VAL A 149 VAL A 168	ERG A 302
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1BXM_A_ERGA99","1bxm","ERG","Ergosterol (DB04038)","Phytophthora cryptogea","BETA-CRYPTOGEIN","Elicitin",25,"TYR A  12;LEU A  15;VAL A  16;ILE A  18;LEU A  19;PHE A  24;TYR A  33;MET A  35;LEU A  36;LEU A  41;PRO A  42;TYR A  47;MET A  50;MET A  59;ILE A  60;ILE A  63;VAL A  75;PRO A  76;THR A  77;LEU A  80;LEU A  82;VAL A  84;TYR A  87;ALA A  88;PHE A  91","ERG A  99\r"],["1ZHZ_A_ERGA1001","1zhz","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae","KES1 PROTEIN","Oxysterol_BP",25,"TRP A  10;PHE A  13;LEU A  24;LEU A  27;ILE A  33;LEU A  39;PHE A  42;TRP A  46;GLN A  96;TYR A  97;ARG A 100;GLU A 107;LYS A 108;LYS A 109;PRO A 110;ASN A 165;ILE A 167;LEU A 177;VAL A 179;GLN A 181;LEU A 201;ILE A 203;ILE A 206;PRO A 211;VAL A 213","ERG A1001\r"],["2AIB_A_ERGA475","2aib","ERG","Ergosterol (DB04038)","Phytophthora cinnamomi","BETA-ELICITIN CINNAMOMIN","Elicitin",27,"TYR A  12;LEU A  15;VAL A  16;ILE A  18;LEU A  19;LEU B  19;PHE A  24;TYR A  33;MET A  35;LEU A  36;LEU A  41;PRO A  42;TYR A  47;MET A  50;MET A  59;ILE A  60;ILE A  63;VAL A  75;PRO A  76;THR B  77;THR A  77;LEU A  80;LEU A  82;VAL A  84;TYR A  87;ALA A  88;PHE A  91","ERG A 475\r"],["5H2D_A_ERGA1301","5h2d","ERG","Ergosterol (DB04038)","Kluyveromyces lactis","KLLA0C04147P","Oxysterol_BP",24,"LEU A 847;LEU A 851;MET A 859;LEU A 864;PHE A 868;LEU A 874;ARG A 877;VAL A 878;ASP A 881;TYR A 912;THR A 915;ARG A 918;VAL A 919;ALA A 920;LYS A 921;PRO A 922;VAL A 971;PHE A 980;PHE A 982;HIS A 984;LYS A1007;ASN A1010;VAL A1012;VAL A1022","ERG A1301\r"],["5YS0_A_ERGA1301","5ys0","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","MEMBRANE-ANCHORED LIPID-BINDING PROTEIN YSP2","VASt",20,"TYR A1115;LYS A1117;LEU A1119;ASN A1121;GLY A1124;THR A1128;CYS A1130;GLN A1149;VAL A1151;SER A1153;VAL A1156;PRO A1157;PHE A1162;VAL A1164;THR A1197;GLY A1201;SER A1202;GLY A1205;GLN A1206;SER A1209","ERG A1301\r"],["6CAY_A_ERGA1101","6cay","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae","STEROL-BINDING PROTEIN","VASt",24,"TYR A 908;LYS A 910;LEU A 912;ILE A 916;GLY A 917;PRO A 918;THR A 921;CYS A 923;ILE A 925;SER A 942;THR A 944;ASN A 946;VAL A 949;PRO A 950;PHE A 955;VAL A 957;THR A 959;PHE A 961;ILE A 991;GLY A 994;THR A 995;GLY A 998;VAL A 999;THR A1002","ERG A1101\r"],["6R4L_A_ERGA1201","6r4l","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1-RELATED PROTEIN 1","NPC1_N;Patched",17,"PHE A 391;TYR A 392;THR A 394;GLN A 396;GLU A 450;GLN A 486;LEU A 492;LEU A 510;VAL A 799;GLY A 800;PRO A 801;PRO A 802;TYR A 804;ARG A 950;SER A 985;PRO A 986;PHE A 987","ERG A1201\r"],["6R4N_A_ERGA302","6r4n","ERG","Ergosterol (DB04038)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","PHOSPHATIDYLGLYCEROL\/PHOSPHATIDYLINOSITOL TRANSFER PROTEIN","E1_DerP2_DerF2",8,"PRO A  67;LEU A  73;VAL A  95;LEU A 102;VAL A 142;TYR A 147;VAL A 149;VAL A 168","ERG A 302\r"]]