Results: Ligand

Ligand ID: BER

Drugbank ID:
Berberine
(DB04115)

Indication:
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal...

LIST OF BINDING INTERFACES for query 'DB04115'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2QVD_A_BERA1811	2qvd	BER	Berberine (DB04115)	Daboia russellii pulchella	PHOSPHOLIPASE A2 VRV-PL-VIIIA	Phospholip_A2_1	12	LEU A 2 PHE A 5 ILE A 9 ALA A 18 ILE A 19 TYR A 22 SER A 23 CYS A 29 GLY A 30 CYS A 45 LYS A 69 PHE A 106	BER A1811
3BTI_A_BERA802	3bti	BER	Berberine (DB04115)	Staphylococcus aureus	HTH-TYPE TRANSCRIPTIONAL REGULATOR QACR	TetR_C_5 TetR_N	11	GLU A 57 GLN A 58 LYS A 60 TRP A 61 GLN A 64 SER A 86 THR A 89 TYR A 93 GLU A 120 TYR A 123 ASN A 157	BER A 802
3D6Y_A_BERA964	3d6y	BER	Berberine (DB04115)	Bacillus subtilis; synthetic construct	MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR	GyrI-like MerR	13	PRO A 144 VAL A 147 ASN A 149 TYR A 152 TYR A 170 ILE A 182 TYR A 187 PHE A 224 PRO A 226 TYR A 229 GLU A 253 ILE A 255 TYR A 268	BER A 964
3VW2_A_BERA301	3vw2	BER	Berberine (DB04115)	Salmonella typhimurium	PUTATIVE REGULATORY PROTEIN	TetR_N	19	TYR A 59 LYS A 63 LEU A 66 THR A 85 TYR A 92 ILE A 106 ALA A 110 CYS A 134 SER A 137 VAL A 138 ARG A 148 GLY A 151 ASP A 152 PHE A 155 LEU A 156 MET A 184 TRP A 185 LEU A 188 THR A 189	BER A 301
4DBK_A_BERA203	4dbk	BER	Berberine (DB04115)	Sus scrofa	PHOSPHOLIPASE A2, MAJOR ISOENZYME	Phospholip_A2_1	12	LEU A 2 PHE A 5 ARG A 6 ILE A 9 PRO A 18 LEU A 19 PHE A 22 ASN A 23 GLY A 30 LEU A 31 ASN A 67 TYR A 69	BER A 203
5Y0V_A_BERA701	5y0v	BER	Berberine (DB04115)	Ostrinia furnacalis	BETA-HEXOSAMINIDASE	Glyco_hydro_20 Glycohydro_20b2	9	TRP A 322 VAL A 327 GLU A 328 ASP A 367 TRP A 448 TYR A 475 TRP A 483 VAL A 484 TRP A 490	BER A 701
7C34_A_BERA501	7c34	BER	Berberine (DB04115)	Serratia marcescens	CHITINASE	Glyco_hydro_18	11	TRP A 97 TYR A 98 GLU A 144 TYR A 145 PHE A 191 ASP A 215 TRP A 220 GLU A 221 ARG A 294 ASP A 316 TYR B 481	BER A 501
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2QVD_A_BERA1811","2qvd","BER","Berberine (DB04115)","Daboia russellii pulchella","PHOSPHOLIPASE A2 VRV-PL-VIIIA","Phospholip_A2_1",12,"LEU A   2;PHE A   5;ILE A   9;ALA A  18;ILE A  19;TYR A  22;SER A  23;CYS A  29;GLY A  30;CYS A  45;LYS A  69;PHE A 106","BER A1811\r"],["3BTI_A_BERA802","3bti","BER","Berberine (DB04115)","Staphylococcus aureus","HTH-TYPE TRANSCRIPTIONAL REGULATOR QACR","TetR_C_5;TetR_N",11,"GLU A  57;GLN A  58;LYS A  60;TRP A  61;GLN A  64;SER A  86;THR A  89;TYR A  93;GLU A 120;TYR A 123;ASN A 157","BER A 802\r"],["3D6Y_A_BERA964","3d6y","BER","Berberine (DB04115)","Bacillus subtilis;synthetic construct","MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR","GyrI-like;MerR",13,"PRO A 144;VAL A 147;ASN A 149;TYR A 152;TYR A 170;ILE A 182;TYR A 187;PHE A 224;PRO A 226;TYR A 229;GLU A 253;ILE A 255;TYR A 268","BER A 964\r"],["3VW2_A_BERA301","3vw2","BER","Berberine (DB04115)","Salmonella typhimurium","PUTATIVE REGULATORY PROTEIN","TetR_N",19,"TYR A  59;LYS A  63;LEU A  66;THR A  85;TYR A  92;ILE A 106;ALA A 110;CYS A 134;SER A 137;VAL A 138;ARG A 148;GLY A 151;ASP A 152;PHE A 155;LEU A 156;MET A 184;TRP A 185;LEU A 188;THR A 189","BER A 301\r"],["4DBK_A_BERA203","4dbk","BER","Berberine (DB04115)","Sus scrofa","PHOSPHOLIPASE A2, MAJOR ISOENZYME","Phospholip_A2_1",12,"LEU A   2;PHE A   5;ARG A   6;ILE A   9;PRO A  18;LEU A  19;PHE A  22;ASN A  23;GLY A  30;LEU A  31;ASN A  67;TYR A  69","BER A 203\r"],["5Y0V_A_BERA701","5y0v","BER","Berberine (DB04115)","Ostrinia furnacalis","BETA-HEXOSAMINIDASE","Glyco_hydro_20;Glycohydro_20b2",9,"TRP A 322;VAL A 327;GLU A 328;ASP A 367;TRP A 448;TYR A 475;TRP A 483;VAL A 484;TRP A 490","BER A 701\r"],["7C34_A_BERA501","7c34","BER","Berberine (DB04115)","Serratia marcescens","CHITINASE","Glyco_hydro_18",11,"TRP A  97;TYR A  98;GLU A 144;TYR A 145;PHE A 191;ASP A 215;TRP A 220;GLU A 221;ARG A 294;ASP A 316;TYR B 481","BER A 501\r"]]