Ligand ID: INS

Drugbank ID:
Inositol
(DB13178)

Indication:
Inositol is an ingredient found in a variety of nutritional products.

LIST OF BINDING INTERFACES for query 'INS'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1AOD_A_INSA296	1aod	INS	Inositol (DB13178)	Listeria monocytogenes	PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C	PI-PLC-X	8	HIS A  45 ARG A  84 ARG A 124 LYS A 126 GLU A 177 ASP A 204 TYR A 206 HIS A 236	INS A 296		Details
1G0I_A_INSA594	1g0i	INS	Inositol (DB13178)	Methanocaldococcus jannaschii	INOSITOL MONOPHOSPHATASE	Inositol_P	7	LYS A 167 ARG A 168 VAL A 169 ARG A 170 TYR B 452 GLY B 473 ARG B 494	INS A 594		Details
1IEV_A_INSA617	1iev	INS	Inositol (DB13178)	Hordeum vulgare	BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1	Glyco_hydro_3 Glyco_hydro_3_C	13	LEU A  54 ASP A  95 PHE A 144 ARG A 158 LYS A 206 HIS A 207 MET A 250 TYR A 253 ASP A 285 TRP A 286 MET A 316 TRP A 430 GLU A 491	INS A 617		Details
1Y7V_A_INSA507	1y7v	INS	Inositol (DB13178)	Homo sapiens	GLUCOSYLCERAMIDASE	Glyco_hydro_30 Glyco_hydro_30C	14	ASP A 127 PHE A 128 TRP A 179 ASN A 234 GLU A 235 PHE A 246 HIS A 311 TYR A 313 GLU A 340 CYS A 342 TRP A 381 ASN A 392 ASN A 396 VAL A 398	INS A 507		Details
2HUO_A_INSA303	2huo	INS	Inositol (DB13178)	Mus musculus	INOSITOL OXYGENASE	MIOX	18	ARG A  29 TYR A  31 TYR A  44 ASP A  85 SER A  87 ASP A  88 PRO A  89 ASP A 124 LYS A 127 VAL A 140 GLY A 141 ASP A 142 HIS A 194 ASP A 195 HIS A 220 SER A 221 TYR A 223 ASP A 253	INS A 303		Details
2OS9_A_INSA631	2os9	INS	Inositol (DB13178)	Homo sapiens	PULMONARY SURFACTANT-ASSOCIATED PROTEIN D	Lectin_C Surfac_D-trimer	7	GLU A 321 ASN A 323 ASP A 325 GLU A 329 ASN A 341 ASP A 342 ARG A 343	INS A 631		Details
2R71_A_INSA787	2r71	INS	Inositol (DB13178)	Bos taurus	LACTOTRANSFERRIN	Transferrin	6	LEU A 651 GLY A 652 GLY A 653 ARG A 654 PRO A 655 GLU A 659	INS A 787		Details
2R71_A_INSA788	2r71	INS	Inositol (DB13178)	Bos taurus	LACTOTRANSFERRIN	Transferrin	7	ASP A 378 THR A 401 ASP A 462 LYS A 673 SER A 676 ALA A 685 PHE A 686	INS A 788		Details
2X1I_A_INSA1503	2x1i	INS	Inositol (DB13178)	Thermus brockianus	4-ALPHA-GLUCANOTRANSFERASE	Glyco_hydro_77	3	PRO A   4 CYS A   5 ARG A  42	INS A1503		Details
2X1I_A_INSA1504	2x1i	INS	Inositol (DB13178)	Thermus brockianus	4-ALPHA-GLUCANOTRANSFERASE	Glyco_hydro_77	4	GLU A  27 ARG A  30 GLY A  31 ARG A  34	INS A1504		Details
3EA2_A_INSA801	3ea2	INS	Inositol (DB13178)	Bacillus thuringiensis	1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE	PI-PLC-X	9	HIS A  32 ASP A  33 ARG A  69 LYS A 115 ARG A 163 TRP A 178 ASP A 198 TYR A 200 PHE A 232	INS A 801		Details
3NT4_A_INSA801	3nt4	INS	Inositol (DB13178)	Bacillus subtilis	INOSITOL 2-DEHYDROGENASE/D-CHIRO-INOSITOL 3-DEHYDROGENASE	GFO_IDH_MocA GFO_IDH_MocA_C	9	LYS A  97 ARG A 127 HIS A 155 ASN A 157 ASP A 172 THR A 173 HIS A 176 TYR A 235 TRP A 272	INS A 801		Details
3V1H_A_INSA401	3v1h	INS	Inositol (DB13178)	Staphylococcus aureus subsp. aureus	1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE	PI-PLC-X	9	HIS A  30 ASP A  31 ARG A  67 LYS A 113 ARG A 166 TRP A 185 ASP A 206 TYR A 208 PHE A 239	INS A 401		Details
4IRX_A_INSA401	4irx	INS	Inositol (DB13178)	Caulobacter crescentus	SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN	Peripla_BP_4	16	GLN A  49 PHE A  51 PHE A  52 ASP A 125 ARG A 126 ASN A 168 ASP A 169 SER A 172 SER A 174 ARG A 178 SER A 203 LEU A 230 ASN A 231 PHE A 257 ASP A 258 GLN A 278	INS A 401		Details
4MIY_D_INSD402	4miy	INS	Inositol (DB13178)	Lactobacillus casei	INOSITOL 2-DEHYDROGENASE/D-CHIRO-INOSITOL 3-DEHYDROGENASE	GFO_IDH_MocA GFO_IDH_MocA_C	11	LYS D  97 MET D 126 HIS D 155 ASN D 157 TYR D 164 ASP D 172 THR D 173 HIS D 176 TYR D 236 TRP D 274 TYR D 282	INS D 402		Details
4RU1_A_INSA401	4ru1	INS	Inositol (DB13178)	Acidothermus cellulolyticus	MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY	Peripla_BP_4	13	HIS A  57 ASP A  62 PHE A  64 TRP A  65 ASN A 137 GLN A 180 GLN A 186 LEU A 187 ARG A 190 LEU A 235 GLY A 236 ASP A 260 GLN A 280	INS A 401		Details
4RXM_A_INSA401	4rxm	INS	Inositol (DB13178)	Mannheimia haemolytica	POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN	NA	12	SER A  36 PHE A  38 GLU A  39 ASP A 112 ARG A 113 SER A 160 ARG A 164 TRP A 189 ASN A 216 PHE A 242 ASP A 243 GLN A 263	INS A 401		Details
4WRE_A_INSA403	4wre	INS	Inositol (DB13178)	Rattus norvegicus	PULMONARY SURFACTANT-ASSOCIATED PROTEIN A	Lectin_C	6	GLU A 195 ASN A 197 GLU A 202 ASN A 214 ASP A 215 ARG A 216	INS A 403		Details
4XF7_A_INSA301	4xf7	INS	Inositol (DB13178)	Thermococcus kodakaraensis kod1	CARBOHYDRATE/PYRIMIDINE KINASE, PFKB FAMILY	NA	16	VAL A  10 ASP A  12 GLY A  25 GLY A  26 GLY A  27 TYR A  30 TYR A  75 LEU A  77 ARG A  85 LEU A  87 VAL A 112 GLN A 136 ARG A 140 THR A 215 GLY A 216 ASP A 219	INS A 301		Details
4YO7_A_INSA405	4yo7	INS	Inositol (DB13178)	Bacillus halodurans	SUGAR ABC TRANSPORTER (SUGAR-BINDING PROTEIN)	Peripla_BP_4	12	ASP A  53 PHE A  55 LEU A  56 ASN A 105 ASN A 130 ARG A 131 ARG A 183 PHE A 207 ASN A 233 ILE A 258 ASP A 259 GLN A 279	INS A 405		Details
5FYR_A_INSA301	5fyr	INS	Inositol (DB13178)	Pseudomonas sp.	PHOSPHOINOSITOL-SPECIFIC PHOSPHOLIPASE C	PI-PLC-C1	11	HIS A  26 ASN A  27 GLU A  48 ILE A 117 ASP A 119 LYS A 121 ASN A 189 HIS A 190 ASN A 240 ARG A 260 TRP A 262	INS A 301		Details
5YSQ_A_INSA301	5ysq	INS	Inositol (DB13178)	Thermotoga maritima (strain atcc 43589 / msb8 / dsm 3109 / jcm 10099)	TM0415	PfkB	14	SER A   9 ASP A  11 GLY A  24 GLY A  25 GLY A  26 ILE A  76 ASN A  78 SER A  89 LEU A 116 GLN A 141 ARG A 145 THR A 230 GLY A 231 ASP A 234	INS A 301		Details
6B5Z_A_INSA308	6b5z	INS	Inositol (DB13178)	Archaeoglobus fulgidus (strain atcc 49558 / vc-16 / dsm 4304 / jcm 9628 / nbrc 100126)	FRUCTOSE-1,6-BISPHOSPHATASE/INOSITOL-1-MONOPHOSPHATASE	Inositol_P	14	ASP A  82 ASP A  85 GLY A  86 TYR A 155 ARG B 167 GLY A 170 SER A 171 ALA A 172 ALA A 173 GLU A 175 ARG A 191 MET A 195 LEU A 196 ASP A 200	INS A 308		Details
6KTL_D_INSD402	6ktl	INS	Inositol (DB13178)	Paracoccus laeviglucosivorans	SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY	GFO_IDH_MocA GFO_IDH_MocA_C	11	PHE D  17 LYS D 106 TYR D 135 TYR D 163 GLU D 165 TYR D 167 ASP D 191 LEU D 192 HIS D 195 CYS D 261 HIS C 318	INS D 402		Details
6X7Z_A_INSA1006	6x7z	INS	Inositol (DB13178)	NA	ANTIFREEZE PROTEIN	NA	12	ARG A  56 ASP A 110 ASP A 111 ASN A 128 GLN A 129 SER A 130 VAL A 131 ASP A 155 GLN A 156 GLY A 157 GLY A 158 ASP A 159	INS A1006		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1AOD_A_INSA296","1aod","INS","Inositol (DB13178)","Listeria monocytogenes","PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C","PI-PLC-X",8,"HIS A 45;ARG A 84;ARG A 124;LYS A 126;GLU A 177;ASP A 204;TYR A 206;HIS A 236","INS A 296\r"],["1G0I_A_INSA594","1g0i","INS","Inositol (DB13178)","Methanocaldococcus jannaschii","INOSITOL MONOPHOSPHATASE","Inositol_P",7,"LYS A 167;ARG A 168;VAL A 169;ARG A 170;TYR B 452;GLY B 473;ARG B 494","INS A 594\r"],["1IEV_A_INSA617","1iev","INS","Inositol (DB13178)","Hordeum vulgare","BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1","Glyco_hydro_3;Glyco_hydro_3_C",13,"LEU A 54;ASP A 95;PHE A 144;ARG A 158;LYS A 206;HIS A 207;MET A 250;TYR A 253;ASP A 285;TRP A 286;MET A 316;TRP A 430;GLU A 491","INS A 617\r"],["1Y7V_A_INSA507","1y7v","INS","Inositol (DB13178)","Homo sapiens","GLUCOSYLCERAMIDASE","Glyco_hydro_30;Glyco_hydro_30C",14,"ASP A 127;PHE A 128;TRP A 179;ASN A 234;GLU A 235;PHE A 246;HIS A 311;TYR A 313;GLU A 340;CYS A 342;TRP A 381;ASN A 392;ASN A 396;VAL A 398","INS A 507\r"],["2HUO_A_INSA303","2huo","INS","Inositol (DB13178)","Mus musculus","INOSITOL OXYGENASE","MIOX",18,"ARG A 29;TYR A 31;TYR A 44;ASP A 85;SER A 87;ASP A 88;PRO A 89;ASP A 124;LYS A 127;VAL A 140;GLY A 141;ASP A 142;HIS A 194;ASP A 195;HIS A 220;SER A 221;TYR A 223;ASP A 253","INS A 303\r"],["2OS9_A_INSA631","2os9","INS","Inositol (DB13178)","Homo sapiens","PULMONARY SURFACTANT-ASSOCIATED PROTEIN D","Lectin_C;Surfac_D-trimer",7,"GLU A 321;ASN A 323;ASP A 325;GLU A 329;ASN A 341;ASP A 342;ARG A 343","INS A 631\r"],["2R71_A_INSA787","2r71","INS","Inositol (DB13178)","Bos taurus","LACTOTRANSFERRIN","Transferrin",6,"LEU A 651;GLY A 652;GLY A 653;ARG A 654;PRO A 655;GLU A 659","INS A 787\r"],["2R71_A_INSA788","2r71","INS","Inositol (DB13178)","Bos taurus","LACTOTRANSFERRIN","Transferrin",7,"ASP A 378;THR A 401;ASP A 462;LYS A 673;SER A 676;ALA A 685;PHE A 686","INS A 788\r"],["2X1I_A_INSA1503","2x1i","INS","Inositol (DB13178)","Thermus brockianus","4-ALPHA-GLUCANOTRANSFERASE","Glyco_hydro_77",3,"PRO A 4;CYS A 5;ARG A 42","INS A1503\r"],["2X1I_A_INSA1504","2x1i","INS","Inositol (DB13178)","Thermus brockianus","4-ALPHA-GLUCANOTRANSFERASE","Glyco_hydro_77",4,"GLU A 27;ARG A 30;GLY A 31;ARG A 34","INS A1504\r"],["3EA2_A_INSA801","3ea2","INS","Inositol (DB13178)","Bacillus thuringiensis","1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE","PI-PLC-X",9,"HIS A 32;ASP A 33;ARG A 69;LYS A 115;ARG A 163;TRP A 178;ASP A 198;TYR A 200;PHE A 232","INS A 801\r"],["3NT4_A_INSA801","3nt4","INS","Inositol (DB13178)","Bacillus subtilis","INOSITOL 2-DEHYDROGENASE\/D-CHIRO-INOSITOL 3-DEHYDROGENASE","GFO_IDH_MocA;GFO_IDH_MocA_C",9,"LYS A 97;ARG A 127;HIS A 155;ASN A 157;ASP A 172;THR A 173;HIS A 176;TYR A 235;TRP A 272","INS A 801\r"],["3V1H_A_INSA401","3v1h","INS","Inositol (DB13178)","Staphylococcus aureus subsp. aureus","1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE","PI-PLC-X",9,"HIS A 30;ASP A 31;ARG A 67;LYS A 113;ARG A 166;TRP A 185;ASP A 206;TYR A 208;PHE A 239","INS A 401\r"],["4IRX_A_INSA401","4irx","INS","Inositol (DB13178)","Caulobacter crescentus","SUGAR ABC TRANSPORTER, PERIPLASMIC SUGAR-BINDING PROTEIN","Peripla_BP_4",16,"GLN A 49;PHE A 51;PHE A 52;ASP A 125;ARG A 126;ASN A 168;ASP A 169;SER A 172;SER A 174;ARG A 178;SER A 203;LEU A 230;ASN A 231;PHE A 257;ASP A 258;GLN A 278","INS A 401\r"],["4MIY_D_INSD402","4miy","INS","Inositol (DB13178)","Lactobacillus casei","INOSITOL 2-DEHYDROGENASE\/D-CHIRO-INOSITOL 3-DEHYDROGENASE","GFO_IDH_MocA;GFO_IDH_MocA_C",11,"LYS D 97;MET D 126;HIS D 155;ASN D 157;TYR D 164;ASP D 172;THR D 173;HIS D 176;TYR D 236;TRP D 274;TYR D 282","INS D 402\r"],["4RU1_A_INSA401","4ru1","INS","Inositol (DB13178)","Acidothermus cellulolyticus","MONOSACCHARIDE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN, CUT2 FAMILY","Peripla_BP_4",13,"HIS A 57;ASP A 62;PHE A 64;TRP A 65;ASN A 137;GLN A 180;GLN A 186;LEU A 187;ARG A 190;LEU A 235;GLY A 236;ASP A 260;GLN A 280","INS A 401\r"],["4RXM_A_INSA401","4rxm","INS","Inositol (DB13178)","Mannheimia haemolytica","POSSIBLE SUGAR ABC SUPERFAMILY ATP BINDING CASSETTE TRANSPORTER, BINDING PROTEIN","NA",12,"SER A 36;PHE A 38;GLU A 39;ASP A 112;ARG A 113;SER A 160;ARG A 164;TRP A 189;ASN A 216;PHE A 242;ASP A 243;GLN A 263","INS A 401\r"],["4WRE_A_INSA403","4wre","INS","Inositol (DB13178)","Rattus norvegicus","PULMONARY SURFACTANT-ASSOCIATED PROTEIN A","Lectin_C",6,"GLU A 195;ASN A 197;GLU A 202;ASN A 214;ASP A 215;ARG A 216","INS A 403\r"],["4XF7_A_INSA301","4xf7","INS","Inositol (DB13178)","Thermococcus kodakaraensis kod1","CARBOHYDRATE\/PYRIMIDINE KINASE, PFKB FAMILY","NA",16,"VAL A 10;ASP A 12;GLY A 25;GLY A 26;GLY A 27;TYR A 30;TYR A 75;LEU A 77;ARG A 85;LEU A 87;VAL A 112;GLN A 136;ARG A 140;THR A 215;GLY A 216;ASP A 219","INS A 301\r"],["4YO7_A_INSA405","4yo7","INS","Inositol (DB13178)","Bacillus halodurans","SUGAR ABC TRANSPORTER (SUGAR-BINDING PROTEIN)","Peripla_BP_4",12,"ASP A 53;PHE A 55;LEU A 56;ASN A 105;ASN A 130;ARG A 131;ARG A 183;PHE A 207;ASN A 233;ILE A 258;ASP A 259;GLN A 279","INS A 405\r"],["5FYR_A_INSA301","5fyr","INS","Inositol (DB13178)","Pseudomonas sp.","PHOSPHOINOSITOL-SPECIFIC PHOSPHOLIPASE C","PI-PLC-C1",11,"HIS A 26;ASN A 27;GLU A 48;ILE A 117;ASP A 119;LYS A 121;ASN A 189;HIS A 190;ASN A 240;ARG A 260;TRP A 262","INS A 301\r"],["5YSQ_A_INSA301","5ysq","INS","Inositol (DB13178)","Thermotoga maritima (strain atcc 43589 \/ msb8 \/ dsm 3109 \/ jcm 10099)","TM0415","PfkB",14,"SER A 9;ASP A 11;GLY A 24;GLY A 25;GLY A 26;ILE A 76;ASN A 78;SER A 89;LEU A 116;GLN A 141;ARG A 145;THR A 230;GLY A 231;ASP A 234","INS A 301\r"],["6B5Z_A_INSA308","6b5z","INS","Inositol (DB13178)","Archaeoglobus fulgidus (strain atcc 49558 \/ vc-16 \/ dsm 4304 \/ jcm 9628 \/ nbrc 100126)","FRUCTOSE-1,6-BISPHOSPHATASE\/INOSITOL-1-MONOPHOSPHATASE","Inositol_P",14,"ASP A 82;ASP A 85;GLY A 86;TYR A 155;ARG B 167;GLY A 170;SER A 171;ALA A 172;ALA A 173;GLU A 175;ARG A 191;MET A 195;LEU A 196;ASP A 200","INS A 308\r"],["6KTL_D_INSD402","6ktl","INS","Inositol (DB13178)","Paracoccus laeviglucosivorans","SCYLLO-INOSITOL DEHYDROGENASE WITH L-GLUCOSE DEHYDROGENASE ACTIVITY","GFO_IDH_MocA;GFO_IDH_MocA_C",11,"PHE D 17;LYS D 106;TYR D 135;TYR D 163;GLU D 165;TYR D 167;ASP D 191;LEU D 192;HIS D 195;CYS D 261;HIS C 318","INS D 402\r"],["6X7Z_A_INSA1006","6x7z","INS","Inositol (DB13178)","NA","ANTIFREEZE PROTEIN","NA",12,"ARG A 56;ASP A 110;ASP A 111;ASN A 128;GLN A 129;SER A 130;VAL A 131;ASP A 155;GLN A 156;GLY A 157;GLY A 158;ASP A 159","INS A1006\r"]]