Ligand ID: FVX

Drugbank ID:
Fluvoxamine
(DB00176)

Indication:
Fluvoxamine is a selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.

LIST OF BINDING INTERFACES for query 'DB00176'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4ENH_A_FVXA602	4enh	FVX	Fluvoxamine (DB00176)	Homo sapiens	CHOLESTEROL 24-HYDROXYLASE	NA	17	PHE A  80 TYR A 109 LEU A 112 PHE A 121 LEU A 219 ILE A 222 ARG A 226 ILE A 301 ALA A 302 THR A 306 ALA A 367 TRP A 368 GLY A 369 THR A 370 PHE A 371 ALA A 474 THR A 475	FVX A 602		Details
4MM9_A_FVXA603	4mm9	FVX	Fluvoxamine (DB00176)	Aquifex aeolicus	TRANSPORTER	SNF	20	TYR A  21 ALA A  22 ASP A  24 PRO A 101 VAL A 104 ALA A 105 TYR A 107 TYR A 108 PHE A 253 SER A 254 LEU A 255 GLY A 256 PHE A 259 VAL A 261 SER A 355 SER A 356 GLY A 359 MET A 360 ASP A 404 THR A 408	FVX A 603		Details
6AWP_A_FVXA701	6awp	FVX	Fluvoxamine (DB00176)	Homo sapiens; mus musculus	SODIUM-DEPENDENT SEROTONIN TRANSPORTER	SNF	20	TYR A  95 ALA A  96 VAL A  97 ASP A  98 ASN A 101 ALA A 169 ILE A 172 ALA A 173 TYR A 175 TYR A 176 PHE A 335 SER A 336 PHE A 341 ASN A 368 SER A 438 SER A 439 GLY A 442 LEU A 443 THR A 497 GLY A 498	FVX A 701		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4ENH_A_FVXA602","4enh","FVX","Fluvoxamine (DB00176)","Homo sapiens","CHOLESTEROL 24-HYDROXYLASE","NA",17,"PHE A 80;TYR A 109;LEU A 112;PHE A 121;LEU A 219;ILE A 222;ARG A 226;ILE A 301;ALA A 302;THR A 306;ALA A 367;TRP A 368;GLY A 369;THR A 370;PHE A 371;ALA A 474;THR A 475","FVX A 602\r"],["4MM9_A_FVXA603","4mm9","FVX","Fluvoxamine (DB00176)","Aquifex aeolicus","TRANSPORTER","SNF",20,"TYR A 21;ALA A 22;ASP A 24;PRO A 101;VAL A 104;ALA A 105;TYR A 107;TYR A 108;PHE A 253;SER A 254;LEU A 255;GLY A 256;PHE A 259;VAL A 261;SER A 355;SER A 356;GLY A 359;MET A 360;ASP A 404;THR A 408","FVX A 603\r"],["6AWP_A_FVXA701","6awp","FVX","Fluvoxamine (DB00176)","Homo sapiens;mus musculus","SODIUM-DEPENDENT SEROTONIN TRANSPORTER","SNF",20,"TYR A 95;ALA A 96;VAL A 97;ASP A 98;ASN A 101;ALA A 169;ILE A 172;ALA A 173;TYR A 175;TYR A 176;PHE A 335;SER A 336;PHE A 341;ASN A 368;SER A 438;SER A 439;GLY A 442;LEU A 443;THR A 497;GLY A 498","FVX A 701\r"]]