Ligand ID: 29E

Drugbank ID:
Duloxetine
(DB00476)

Indication:
Duloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.

LIST OF BINDING INTERFACES for query '29E'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4MMD_A_29EA603	4mmd	29E	Duloxetine (DB00476)	Aquifex aeolicus	TRANSPORTER	SNF	18	TYR A  21 ALA A  22 ASP A  24 PRO A 101 VAL A 104 ALA A 105 TYR A 107 TYR A 108 VAL A 109 PHE A 253 SER A 254 LEU A 255 GLY A 256 PHE A 259 SER A 355 SER A 356 GLY A 359 MET A 360	29E A 603		Details
6M38_A_29EA601	6m38	29E	Duloxetine (DB00476)	Drosophila melanogaster; mus musculus	SODIUM-DEPENDENT DOPAMINE TRANSPORTER	SNF	16	PHE A  43 ALA A  44 ASP A  46 ALA A 117 VAL A 120 GLY A 121 TYR A 123 TYR A 124 PHE A 319 SER A 320 LEU A 321 PHE A 325 SER A 421 SER A 422 GLY A 425 ALA A 479	29E A 601		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4MMD_A_29EA603","4mmd","29E","Duloxetine (DB00476)","Aquifex aeolicus","TRANSPORTER","SNF",18,"TYR A 21;ALA A 22;ASP A 24;PRO A 101;VAL A 104;ALA A 105;TYR A 107;TYR A 108;VAL A 109;PHE A 253;SER A 254;LEU A 255;GLY A 256;PHE A 259;SER A 355;SER A 356;GLY A 359;MET A 360","29E A 603\r"],["6M38_A_29EA601","6m38","29E","Duloxetine (DB00476)","Drosophila melanogaster;mus musculus","SODIUM-DEPENDENT DOPAMINE TRANSPORTER","SNF",16,"PHE A 43;ALA A 44;ASP A 46;ALA A 117;VAL A 120;GLY A 121;TYR A 123;TYR A 124;PHE A 319;SER A 320;LEU A 321;PHE A 325;SER A 421;SER A 422;GLY A 425;ALA A 479","29E A 601\r"]]