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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2gvc | MMZ | Methimazole (DB00763) | Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. | MONOOXYGENASE (Schizosaccharomyces pombe) | FMO-likeNAD_binding_8 | ||
| 2huo | INS | Inositol (DB13178) | Inositol is an ingredient found in a variety of nutritional products. | INOSITOL OXYGENASE (Mus musculus) | MIOX | ||
| 3njz | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | GENTISATE 1,2-DIOXYGENASE (Pseudaminobacter salicylatoxidans) | Cupin_2 | ||
| 3pgh | FLP | Flurbiprofen (DB00712) | Flurbiprofen is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | CYCLOOXYGENASE-2 (Mus musculus) | An_peroxidaseEGF | ||
| 3q2a | PAB | Aminobenzoic acid (DB02362) | Aminobenzoic acid is a drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN A (Pseudomonas mendocina) | Phenol_Hydrox | ||
| 3q2a | PAB | Aminobenzoic acid (DB02362) | Aminobenzoic acid is a drug used to reduce the progression of penile deviation in Peyronie's Disease in adults. | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN A;TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN E (Pseudomonas mendocina) | Phenol_Hydrox | ||
| 4cox | IMN | Indomethacin (DB00328) | Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | CYCLOOXYGENASE-2 (Mus musculus) | An_peroxidaseEGF | ||
| 4eis | DAH | Levodopa (DB01235) | Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. | POLYSACCHARIDE MONOOXYGENASE-3 (Neurospora crassa) | AA9 | ||
| 4hvr | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE (Cupriavidus metallidurans) | 3-HAO | ||
| 4j6b | PLO | Pregnenolone (DB02789) | A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids. | CYTOCHROME P450 MONOOXYGENASE (Nocardia farcinica) | p450 | ||
| 4j6c | STR | Progesterone (DB00396) | Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. | CYTOCHROME P450 MONOOXYGENASE (Nocardia farcinica) | p450 | ||
| 4j6d | TES | Testosterone (DB00624) | Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. | CYTOCHROME P450 MONOOXYGENASE (Nocardia farcinica) | p450 | ||
| 4qkn | JMS | Meclofenamic acid (DB00939) | Meclofenamic acid is an NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. | ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO (Homo sapiens) | FTO_CTDFTO_NTD | ||
| 4zs2 | FLU | Fluorescein (DB00693) | Fluorescein is a dye used in angiography or angioscopy of the iris and retina. | ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO (Homo sapiens) | FTO_CTDFTO_NTD | ||
| 5gsn | MMZ | Methimazole (DB00763) | Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism. | FLAVIN-CONTAINING MONOOXYGENASE (Roseovarius nubinhibens (strain atcc baa-591 / dsm 15170 / ism)) | FMO-like | ||
| 5pah | LDP | Dopamine (DB00988) | Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. | PHENYLALANINE 4-MONOOXYGENASE (Homo sapiens) | NA | ||
| 6ak4 | PD9 | Entacapone (DB00494) | Entacapone is a selective reversible catechol-O-methyltransferase inhibitor for the treatment of Parkinson's disease. | ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO (Homo sapiens) | FTO_CTDFTO_NTD | ||
| 6n2w | 30Z | Masoprocol (DB00179) | A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in... | ARACHIDONATE 5-LIPOXYGENASE (Homo sapiens) | LipoxygenasePLAT | ||
| 6on3 | DAH | Levodopa (DB01235) | Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. | L-DOPA EXTRADIOL DIOXYGENASE (Streptomyces sclerotialus) | Glyoxalase | ||
| 6pah | DAH | Levodopa (DB01235) | Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism. | PHENYLALANINE 4-MONOOXYGENASE (Homo sapiens) | NA | ||
| 6s0s | RIO | Ribostamycin (DB03615) | Ribostamycin is a broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine. | KANAMYCIN B DIOXYGENASE (Streptomyces kanamyceticus) | PhyH | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |