Ligand ID: PLO

Drugbank ID:
Pregnenolone
(DB02789)

Indication:
A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.

LIST OF BINDING INTERFACES for query 'PLO'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1Q20_A_PLOA401	1q20	PLO	Pregnenolone (DB02789)	Homo sapiens	SULFOTRANSFERASE FAMILY, CYTOSOLIC, 2B, MEMBER 1 ISOFORM B	Sulfotransfer_1	14	ILE A  20 LEU A  43 TYR A  44 TRP A  98 TRP A 103 THR A 106 VAL A 108 HIS A 125 TYR A 159 GLN A 165 TYR A 257 LEU A 260 LEU A 264 PHE A 272	PLO A 401		Details
4J6B_A_PLOA501	4j6b	PLO	Pregnenolone (DB02789)	Nocardia farcinica	CYTOCHROME P450 MONOOXYGENASE	p450	15	GLY A  83 MET A  84 VAL A  87 PHE A  92 PHE A 179 PHE A 180 MET A 196 GLN A 239 ALA A 240 ALA A 243 ALA A 244 THR A 248 VAL A 291 LEU A 294 GLN A 398	PLO A 501		Details
4NKW_A_PLOA601	4nkw	PLO	Pregnenolone (DB02789)	Homo sapiens	STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE	p450	20	LEU A 105 ALA A 113 PHE A 114 TYR A 201 ASN A 202 ILE A 205 ILE A 206 LEU A 209 ARG A 239 GLY A 297 ASP A 298 GLY A 301 ALA A 302 GLU A 305 THR A 306 VAL A 366 ALA A 367 ILE A 371 VAL A 482 VAL A 483	PLO A 601		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1Q20_A_PLOA401","1q20","PLO","Pregnenolone (DB02789)","Homo sapiens","SULFOTRANSFERASE FAMILY, CYTOSOLIC, 2B, MEMBER 1 ISOFORM B","Sulfotransfer_1",14,"ILE A 20;LEU A 43;TYR A 44;TRP A 98;TRP A 103;THR A 106;VAL A 108;HIS A 125;TYR A 159;GLN A 165;TYR A 257;LEU A 260;LEU A 264;PHE A 272","PLO A 401\r"],["4J6B_A_PLOA501","4j6b","PLO","Pregnenolone (DB02789)","Nocardia farcinica","CYTOCHROME P450 MONOOXYGENASE","p450",15,"GLY A 83;MET A 84;VAL A 87;PHE A 92;PHE A 179;PHE A 180;MET A 196;GLN A 239;ALA A 240;ALA A 243;ALA A 244;THR A 248;VAL A 291;LEU A 294;GLN A 398","PLO A 501\r"],["4NKW_A_PLOA601","4nkw","PLO","Pregnenolone (DB02789)","Homo sapiens","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","p450",20,"LEU A 105;ALA A 113;PHE A 114;TYR A 201;ASN A 202;ILE A 205;ILE A 206;LEU A 209;ARG A 239;GLY A 297;ASP A 298;GLY A 301;ALA A 302;GLU A 305;THR A 306;VAL A 366;ALA A 367;ILE A 371;VAL A 482;VAL A 483","PLO A 601\r"]]