Results: Ligand

Ligand ID: FLP

Drugbank ID:
Flurbiprofen
(DB00712)

Indication:
Flurbiprofen is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.

LIST OF BINDING INTERFACES for query 'FLP'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1DVT_A_FLPA125	1dvt	FLP	Flurbiprofen (DB00712)	Homo sapiens	TRANSTHYRETIN	Transthyretin	13	LYS B 15 LYS A 15 LEU B 17 LEU A 17 THR A 106 ALA A 108 ALA B 108 LEU B 110 LEU A 110 SER A 117 SER B 117 THR B 118 THR B 119	FLP A 125
1R9O_A_FLPA501	1r9o	FLP	Flurbiprofen (DB00712)	Homo sapiens	CYTOCHROME P450 2C9	p450	16	ARG A 108 VAL A 113 PHE A 114 LEU A 201 ASN A 204 ILE A 205 LEU A 208 VAL A 237 MET A 240 VAL A 292 ASP A 293 GLY A 296 ALA A 297 THR A 301 LEU A 362 LEU A 366	FLP A 501
2AYL_A_FLPA1701	2ayl	FLP	Flurbiprofen (DB00712)	Ovis aries	PROSTAGLANDIN G/H SYNTHASE 1	An_peroxidase EGF	18	VAL A 116 ARG A 120 TYR A 348 VAL A 349 LEU A 352 SER A 353 TYR A 355 LEU A 359 LEU A 384 TYR A 385 TRP A 387 PHE A 518 MET A 522 ILE A 523 GLY A 526 ALA A 527 SER A 530 LEU A 531	FLP A1701
3PGH_A_FLPA701	3pgh	FLP	Flurbiprofen (DB00712)	Mus musculus	CYCLOOXYGENASE-2	An_peroxidase EGF	16	VAL A 116 ARG A 120 VAL A 349 LEU A 352 SER A 353 TYR A 355 LEU A 359 PHE A 381 TYR A 385 TRP A 387 MET A 522 VAL A 523 GLY A 526 ALA A 527 SER A 530 LEU A 531	FLP A 701
4FOR_A_FLPA711	4for	FLP	Flurbiprofen (DB00712)	Bos taurus	LACTOTRANSFERRIN	Transferrin	12	ALA A 412 THR A 430 GLU A 431 GLY A 432 VAL A 591 ALA A 592 PRO A 593 ASN A 594 TYR A 660 LEU A 661 GLY A 662 GLU A 664	FLP A 711
4JTQ_A_FLPA401	4jtq	FLP	Flurbiprofen (DB00712)	Homo sapiens	ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2	Aldo_ket_red	11	TYR A 24 VAL A 54 TYR A 55 TRP A 86 HIS A 117 VAL A 128 ILE A 129 TRP A 227 LEU A 306 LEU A 308 PHE A 311	FLP A 401
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1DVT_A_FLPA125","1dvt","FLP","Flurbiprofen (DB00712)","Homo sapiens","TRANSTHYRETIN","Transthyretin",13,"LYS B  15;LYS A  15;LEU B  17;LEU A  17;THR A 106;ALA A 108;ALA B 108;LEU B 110;LEU A 110;SER A 117;SER B 117;THR B 118;THR B 119","FLP A 125\r"],["1R9O_A_FLPA501","1r9o","FLP","Flurbiprofen (DB00712)","Homo sapiens","CYTOCHROME P450 2C9","p450",16,"ARG A 108;VAL A 113;PHE A 114;LEU A 201;ASN A 204;ILE A 205;LEU A 208;VAL A 237;MET A 240;VAL A 292;ASP A 293;GLY A 296;ALA A 297;THR A 301;LEU A 362;LEU A 366","FLP A 501\r"],["2AYL_A_FLPA1701","2ayl","FLP","Flurbiprofen (DB00712)","Ovis aries","PROSTAGLANDIN G\/H SYNTHASE 1","An_peroxidase;EGF",18,"VAL A 116;ARG A 120;TYR A 348;VAL A 349;LEU A 352;SER A 353;TYR A 355;LEU A 359;LEU A 384;TYR A 385;TRP A 387;PHE A 518;MET A 522;ILE A 523;GLY A 526;ALA A 527;SER A 530;LEU A 531","FLP A1701\r"],["3PGH_A_FLPA701","3pgh","FLP","Flurbiprofen (DB00712)","Mus musculus","CYCLOOXYGENASE-2","An_peroxidase;EGF",16,"VAL A 116;ARG A 120;VAL A 349;LEU A 352;SER A 353;TYR A 355;LEU A 359;PHE A 381;TYR A 385;TRP A 387;MET A 522;VAL A 523;GLY A 526;ALA A 527;SER A 530;LEU A 531","FLP A 701\r"],["4FOR_A_FLPA711","4for","FLP","Flurbiprofen (DB00712)","Bos taurus","LACTOTRANSFERRIN","Transferrin",12,"ALA A 412;THR A 430;GLU A 431;GLY A 432;VAL A 591;ALA A 592;PRO A 593;ASN A 594;TYR A 660;LEU A 661;GLY A 662;GLU A 664","FLP A 711\r"],["4JTQ_A_FLPA401","4jtq","FLP","Flurbiprofen (DB00712)","Homo sapiens","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","Aldo_ket_red",11,"TYR A  24;VAL A  54;TYR A  55;TRP A  86;HIS A 117;VAL A 128;ILE A 129;TRP A 227;LEU A 306;LEU A 308;PHE A 311","FLP A 401\r"]]