Ligand ID: MMZ

Drugbank ID:
Methimazole
(DB00763)

Indication:
Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.

LIST OF BINDING INTERFACES for query 'MMZ'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2GVC_A_MMZA501	2gvc	MMZ	Methimazole (DB00763)	Schizosaccharomyces pombe	MONOOXYGENASE	FMO-like NAD_binding_8	5	ASN A  91 TYR A 176 SER A 222 SER A 223 TYR A 290	MMZ A 501		Details
5FF1_A_MMZA601	5ff1	MMZ	Methimazole (DB00763)	Capra hircus	LACTOPEROXIDASE	An_peroxidase	5	GLN A 105 HIS A 109 ARG A 255 GLU A 258 LEU A 262	MMZ A 601		Details
5FF1_A_MMZA602	5ff1	MMZ	Methimazole (DB00763)	Capra hircus	LACTOPEROXIDASE	An_peroxidase	5	GLN A 105 HIS A 109 ARG A 255 GLU A 258 LEU A 262	MMZ A 602		Details
5GSN_A_MMZA503	5gsn	MMZ	Methimazole (DB00763)	Roseovarius nubinhibens (strain atcc baa-591 / dsm 15170 / ism)	FLAVIN-CONTAINING MONOOXYGENASE	FMO-like	5	TYR A  67 ASN A  73 SER A 207 SER A 208 ASP A 211	MMZ A 503		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2GVC_A_MMZA501","2gvc","MMZ","Methimazole (DB00763)","Schizosaccharomyces pombe","MONOOXYGENASE","FMO-like;NAD_binding_8",5,"ASN A 91;TYR A 176;SER A 222;SER A 223;TYR A 290","MMZ A 501\r"],["5FF1_A_MMZA601","5ff1","MMZ","Methimazole (DB00763)","Capra hircus","LACTOPEROXIDASE","An_peroxidase",5,"GLN A 105;HIS A 109;ARG A 255;GLU A 258;LEU A 262","MMZ A 601\r"],["5FF1_A_MMZA602","5ff1","MMZ","Methimazole (DB00763)","Capra hircus","LACTOPEROXIDASE","An_peroxidase",5,"GLN A 105;HIS A 109;ARG A 255;GLU A 258;LEU A 262","MMZ A 602\r"],["5GSN_A_MMZA503","5gsn","MMZ","Methimazole (DB00763)","Roseovarius nubinhibens (strain atcc baa-591 \/ dsm 15170 \/ ism)","FLAVIN-CONTAINING MONOOXYGENASE","FMO-like",5,"TYR A 67;ASN A 73;SER A 207;SER A 208;ASP A 211","MMZ A 503\r"]]