Ligand ID: MMZ

Drugbank ID:
Methimazole
(DB00763)

Indication:
Methimazole is a thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.


LIST OF BINDING INTERFACES for query 'DB00763'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
2GVC_A_MMZA5012gvc MMZMethimazole
(DB00763) 		Schizosaccharomyces pombe MONOOXYGENASE FMO-like
NAD_binding_8 		5ASN A  91
TYR A 176
SER A 222
SER A 223
TYR A 290
MMZ A 501
5FF1_A_MMZA6015ff1 MMZMethimazole
(DB00763) 		Capra hircus LACTOPEROXIDASE An_peroxidase 5GLN A 105
HIS A 109
ARG A 255
GLU A 258
LEU A 262
MMZ A 601
5FF1_A_MMZA6025ff1 MMZMethimazole
(DB00763) 		Capra hircus LACTOPEROXIDASE An_peroxidase 5GLN A 105
HIS A 109
ARG A 255
GLU A 258
LEU A 262
MMZ A 602
5GSN_A_MMZA5035gsn MMZMethimazole
(DB00763) 		Roseovarius nubinhibens (strain atcc baa-591 / dsm 15170 / ism) FLAVIN-CONTAINING MONOOXYGENASE FMO-like 5TYR A  67
ASN A  73
SER A 207
SER A 208
ASP A 211
MMZ A 503
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details