Results: Ligand

Ligand ID: TES

Drugbank ID:
Testosterone
(DB00624)

Indication:
Testosterone is a hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause.

LIST OF BINDING INTERFACES for query 'DB00624'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1AFS_A_TESA325	1afs	TES	Testosterone (DB00624)	Rattus norvegicus	3-ALPHA-HYDROXYSTEROID DEHYDROGENASE	Aldo_ket_red	11	THR A 24 GLU A 27 LEU A 54 TYR A 55 HIS A 117 PHE A 118 PHE A 129 THR A 226 TRP A 227 ASN A 306 TYR A 310	TES A 325
1J96_A_TESA903	1j96	TES	Testosterone (DB00624)	Homo sapiens	3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3	Aldo_ket_red	11	TYR A 24 VAL A 54 TYR A 55 TRP A 86 VAL A 128 ILE A 129 HIS A 222 GLU A 224 TRP A 227 LEU A 306 LEU A 308	TES A 903
1JTV_A_TESA500	1jtv	TES	Testosterone (DB00624)	Homo sapiens	17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1	adh_short	13	VAL A 143 LEU A 149 PRO A 187 TYR A 218 HIS A 221 SER A 222 VAL A 225 PHE A 226 PHE A 259 LEU A 262 MET A 279 GLU A 282 VAL A 283	TES A 500
1Q13_A_TESA501	1q13	TES	Testosterone (DB00624)	Oryctolagus cuniculus	PROSTAGLANDIN-E2 9-REDUCTASE	Aldo_ket_red	10	TYR A 24 PHE A 54 TYR A 55 HIS A 117 PHE A 118 ILE A 129 GLU A 224 PRO A 225 VAL A 306 PHE A 310	TES A 501
1VPO_H_TESH1010	1vpo	TES	Testosterone (DB00624)	Mus musculus	ANTI-TESTOSTERONE (HEAVY CHAIN); ANTI-TESTOSTERONE (LIGHT CHAIN)	NA	17	ARG L 32 ALA H 33 SER H 35 GLU L 39 TRP H 47 SER H 50 VAL H 52 TYR H 58 PHE L 94 GLY L 96 ALA H 98 VAL L 99 PRO L 101 TYR H 102 VAL H 103 GLY H 104 LEU H 105	TES H1010
2AM9_A_TESA1000	2am9	TES	Testosterone (DB00624)	Homo sapiens	ANDROGEN RECEPTOR	Hormone_recep	21	LEU A 701 LEU A 704 ASN A 705 LEU A 707 GLY A 708 GLN A 711 TRP A 741 MET A 742 MET A 745 VAL A 746 MET A 749 ARG A 752 PHE A 764 MET A 780 MET A 787 LEU A 873 PHE A 876 THR A 877 LEU A 880 PHE A 891 MET A 895	TES A1000
3BUR_A_TESA339	3bur	TES	Testosterone (DB00624)	Homo sapiens	3-OXO-5-BETA-STEROID 4-DEHYDROGENASE	Aldo_ket_red	14	TYR A 26 ILE A 57 TYR A 58 TRP A 89 TYR A 132 THR A 224 SER A 225 ARG A 226 ASN A 227 TRP A 230 VAL A 231 VAL A 309 LEU A 311 TRP A 314	TES A 339
3KDM_H_TESH226	3kdm	TES	Testosterone (DB00624)	Homo sapiens	IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN	NA	12	ALA H 33 SER H 35 TRP H 47 ALA H 50 TYR H 59 ASP H 99 PRO L 99 TYR L 100 TYR H 105 TYR H 107 GLY H 108 MET H 109	TES H 226
4J6D_A_TESA503	4j6d	TES	Testosterone (DB00624)	Nocardia farcinica	CYTOCHROME P450 MONOOXYGENASE	p450	14	GLY A 83 MET A 84 VAL A 87 PHE A 92 PHE A 179 PHE A 180 GLN A 239 ALA A 240 ALA A 243 ALA A 244 THR A 248 VAL A 291 LEU A 294 GLN A 398	TES A 503
5JKW_A_TESA601	5jkw	TES	Testosterone (DB00624)	Homo sapiens	AROMATASE	p450	14	ARG A 115 ILE A 133 PHE A 134 PHE A 221 TRP A 224 ILE A 305 ALA A 306 ASP A 309 THR A 310 VAL A 370 LEU A 372 VAL A 373 MET A 374 LEU A 477	TES A 601
5L94_A_TESA502	5l94	TES	Testosterone (DB00624)	Bacillus megaterium (strain dsm 319)	CYTOCHROME P450	p450	12	ILE A 85 ILE A 168 VAL A 169 LEU A 238 ILE A 241 ALA A 242 THR A 246 VAL A 289 ALA A 291 HIS A 293 PHE A 391 VAL A 392	TES A 502
6A7J_A_TESA502	6a7j	TES	Testosterone (DB00624)	Streptomyces violaceoruber	CYTOCHROME P450	p450	13	GLY A 78 LEU A 79 PRO A 82 LEU A 87 PHE A 173 PHE A 174 GLN A 233 LEU A 234 ALA A 237 ALA A 238 THR A 242 THR A 285 GLN A 391	TES A 502
6HGL_A_TESA401	6hgl	TES	Testosterone (DB00624)	Homo sapiens	ALPHA-1-ANTICHYMOTRYPSIN	NA	12	ARG A 24 ALA A 27 SER A 28 VAL A 31 PHE A 252 ARG A 270 LEU A 273 ALA A 274 GLY A 277 VAL B 381 HIS B 383 TRP B 386	TES A 401
6LY4_A_TESA501	6ly4	TES	Testosterone (DB00624)	Bacillus megaterium (strain atcc 14581 / dsm 32 / jcm 2506 / nbrc 15308 / ncimb 9376 / nctc 10342 / vkm b-512)	BIFUNCTIONAL CYTOCHROME P450/NADPH--P450 REDUCTASE	p450	18	TRP A 72 LEU A 75 LEU A 78 LEU A 82 LEU A 86 GLY A 87 SER A 88 LEU A 181 THR A 260 ILE A 263 ALA A 264 GLU A 267 THR A 327 GLY A 328 PRO A 329 TRP A 330 LEU A 437 THR A 438	TES A 501
6MDQ_A_TESA604	6mdq	TES	Testosterone (DB00624)	Equus caballus	SERUM ALBUMIN	Serum_albumin	11	ARG A 208 LYS A 211 ALA A 212 VAL A 215 ASP A 323 LEU A 326 GLY A 327 LEU A 330 ALA A 349 LYS A 350 GLU A 353	TES A 604
6MDQ_A_TESA605	6mdq	TES	Testosterone (DB00624)	Equus caballus	SERUM ALBUMIN	Serum_albumin	10	LYS A 17 HIS A 18 LYS A 20 GLY A 21 ASP A 131 LEU A 134 GLY A 135 LEU A 138 ALA A 157 GLU A 158	TES A 605
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1AFS_A_TESA325","1afs","TES","Testosterone (DB00624)","Rattus norvegicus","3-ALPHA-HYDROXYSTEROID DEHYDROGENASE","Aldo_ket_red",11,"THR A  24;GLU A  27;LEU A  54;TYR A  55;HIS A 117;PHE A 118;PHE A 129;THR A 226;TRP A 227;ASN A 306;TYR A 310","TES A 325\r"],["1J96_A_TESA903","1j96","TES","Testosterone (DB00624)","Homo sapiens","3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3","Aldo_ket_red",11,"TYR A  24;VAL A  54;TYR A  55;TRP A  86;VAL A 128;ILE A 129;HIS A 222;GLU A 224;TRP A 227;LEU A 306;LEU A 308","TES A 903\r"],["1JTV_A_TESA500","1jtv","TES","Testosterone (DB00624)","Homo sapiens","17 BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1","adh_short",13,"VAL A 143;LEU A 149;PRO A 187;TYR A 218;HIS A 221;SER A 222;VAL A 225;PHE A 226;PHE A 259;LEU A 262;MET A 279;GLU A 282;VAL A 283","TES A 500\r"],["1Q13_A_TESA501","1q13","TES","Testosterone (DB00624)","Oryctolagus cuniculus","PROSTAGLANDIN-E2 9-REDUCTASE","Aldo_ket_red",10,"TYR A  24;PHE A  54;TYR A  55;HIS A 117;PHE A 118;ILE A 129;GLU A 224;PRO A 225;VAL A 306;PHE A 310","TES A 501\r"],["1VPO_H_TESH1010","1vpo","TES","Testosterone (DB00624)","Mus musculus","ANTI-TESTOSTERONE (HEAVY CHAIN);ANTI-TESTOSTERONE (LIGHT CHAIN)","NA",17,"ARG L  32;ALA H  33;SER H  35;GLU L  39;TRP H  47;SER H  50;VAL H  52;TYR H  58;PHE L  94;GLY L  96;ALA H  98;VAL L  99;PRO L 101;TYR H 102;VAL H 103;GLY H 104;LEU H 105","TES H1010\r"],["2AM9_A_TESA1000","2am9","TES","Testosterone (DB00624)","Homo sapiens","ANDROGEN RECEPTOR","Hormone_recep",21,"LEU A 701;LEU A 704;ASN A 705;LEU A 707;GLY A 708;GLN A 711;TRP A 741;MET A 742;MET A 745;VAL A 746;MET A 749;ARG A 752;PHE A 764;MET A 780;MET A 787;LEU A 873;PHE A 876;THR A 877;LEU A 880;PHE A 891;MET A 895","TES A1000\r"],["3BUR_A_TESA339","3bur","TES","Testosterone (DB00624)","Homo sapiens","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","Aldo_ket_red",14,"TYR A  26;ILE A  57;TYR A  58;TRP A  89;TYR A 132;THR A 224;SER A 225;ARG A 226;ASN A 227;TRP A 230;VAL A 231;VAL A 309;LEU A 311;TRP A 314","TES A 339\r"],["3KDM_H_TESH226","3kdm","TES","Testosterone (DB00624)","Homo sapiens","IMMUNOGLOBULIN HEAVY CHAIN;IMMUNOGLOBULIN LIGHT CHAIN","NA",12,"ALA H  33;SER H  35;TRP H  47;ALA H  50;TYR H  59;ASP H  99;PRO L  99;TYR L 100;TYR H 105;TYR H 107;GLY H 108;MET H 109","TES H 226\r"],["4J6D_A_TESA503","4j6d","TES","Testosterone (DB00624)","Nocardia farcinica","CYTOCHROME P450 MONOOXYGENASE","p450",14,"GLY A  83;MET A  84;VAL A  87;PHE A  92;PHE A 179;PHE A 180;GLN A 239;ALA A 240;ALA A 243;ALA A 244;THR A 248;VAL A 291;LEU A 294;GLN A 398","TES A 503\r"],["5JKW_A_TESA601","5jkw","TES","Testosterone (DB00624)","Homo sapiens","AROMATASE","p450",14,"ARG A 115;ILE A 133;PHE A 134;PHE A 221;TRP A 224;ILE A 305;ALA A 306;ASP A 309;THR A 310;VAL A 370;LEU A 372;VAL A 373;MET A 374;LEU A 477","TES A 601\r"],["5L94_A_TESA502","5l94","TES","Testosterone (DB00624)","Bacillus megaterium (strain dsm 319)","CYTOCHROME P450","p450",12,"ILE A  85;ILE A 168;VAL A 169;LEU A 238;ILE A 241;ALA A 242;THR A 246;VAL A 289;ALA A 291;HIS A 293;PHE A 391;VAL A 392","TES A 502\r"],["6A7J_A_TESA502","6a7j","TES","Testosterone (DB00624)","Streptomyces violaceoruber","CYTOCHROME P450","p450",13,"GLY A  78;LEU A  79;PRO A  82;LEU A  87;PHE A 173;PHE A 174;GLN A 233;LEU A 234;ALA A 237;ALA A 238;THR A 242;THR A 285;GLN A 391","TES A 502\r"],["6HGL_A_TESA401","6hgl","TES","Testosterone (DB00624)","Homo sapiens","ALPHA-1-ANTICHYMOTRYPSIN","NA",12,"ARG A  24;ALA A  27;SER A  28;VAL A  31;PHE A 252;ARG A 270;LEU A 273;ALA A 274;GLY A 277;VAL B 381;HIS B 383;TRP B 386","TES A 401\r"],["6LY4_A_TESA501","6ly4","TES","Testosterone (DB00624)","Bacillus megaterium (strain atcc 14581 \/ dsm 32 \/ jcm 2506 \/ nbrc 15308 \/ ncimb 9376 \/ nctc 10342 \/ vkm b-512)","BIFUNCTIONAL CYTOCHROME P450\/NADPH--P450 REDUCTASE","p450",18,"TRP A  72;LEU A  75;LEU A  78;LEU A  82;LEU A  86;GLY A  87;SER A  88;LEU A 181;THR A 260;ILE A 263;ALA A 264;GLU A 267;THR A 327;GLY A 328;PRO A 329;TRP A 330;LEU A 437;THR A 438","TES A 501\r"],["6MDQ_A_TESA604","6mdq","TES","Testosterone (DB00624)","Equus caballus","SERUM ALBUMIN","Serum_albumin",11,"ARG A 208;LYS A 211;ALA A 212;VAL A 215;ASP A 323;LEU A 326;GLY A 327;LEU A 330;ALA A 349;LYS A 350;GLU A 353","TES A 604\r"],["6MDQ_A_TESA605","6mdq","TES","Testosterone (DB00624)","Equus caballus","SERUM ALBUMIN","Serum_albumin",10,"LYS A  17;HIS A  18;LYS A  20;GLY A  21;ASP A 131;LEU A 134;GLY A 135;LEU A 138;ALA A 157;GLU A 158","TES A 605\r"]]