Ligand ID: RIO

Drugbank ID:
Ribostamycin
(DB03615)

Indication:
Ribostamycin is a broad spectrum aminoglycoside antibiotic on the list of WHO critical antimicrobials for human medicine.

LIST OF BINDING INTERFACES for query 'DB03615'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1M4G_A_RIOA500	1m4g	RIO	Ribostamycin (DB03615)	Mycobacterium tuberculosis	AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE	Acetyltransf_9	18	PHE A  32 ASP A  35 PHE A  36 ASP A  40 VAL A  81 GLU A  82 GLY A  83 SER A 117 SER A 118 SER A 119 ALA A 120 ARG A 121 ARG A 123 ASP A 151 ASP A 152 THR A 155 ASP A 179 TRP A 181	RIO A 500		Details
1S3Z_A_RIOA500	1s3z	RIO	Ribostamycin (DB03615)	Salmonella enteritidis	AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE	Acetyltransf_1	11	ARG A  18 TRP A  22 PRO A  23 HIS A  25 TYR B  66 ASN B  68 GLU A  79 ASP A 115 THR A 116 GLU B 136 VAL B 138	RIO A 500		Details
2BUE_A_RIOA1201	2bue	RIO	Ribostamycin (DB03615)	Escherichia coli	AAC(6')-IB	Acetyltransf_8	16	TRP A  48 TRP A  49 GLY A  50 GLY A  51 TYR A  65 LEU A  70 GLU A  73 VAL A  75 GLN A  91 TYR A  93 SER A  98 TRP A 102 TRP A 103 ASP A 115 ASP A 152 ASP A 179	RIO A1201		Details
5IQD_A_RIOA600	5iqd	RIO	Ribostamycin (DB03615)	Staphylococcus aureus	BIFUNCTIONAL AAC/APH	APH	13	ASP A 374 SER A 376 ASN A 378 HIS A 379 TYR A 408 GLU A 411 SER A 413 GLU A 415 GLU A 416 VAL A 444 GLU A 445 TYR A 448 GLU A 451	RIO A 600		Details
6S0S_A_RIOA303	6s0s	RIO	Ribostamycin (DB03615)	Streptomyces kanamyceticus	KANAMYCIN B DIOXYGENASE	PhyH	20	ASN A  73 PHE A  74 GLN A  80 VAL A 116 SER A 118 GLY A 119 ASN A 120 HIS A 132 LEU A 133 ASP A 134 GLU A 135 CYS A 150 ASP A 152 ARG A 183 GLY A 184 ARG A 213 ALA A 234 THR A 236 TYR A 238 MET A 244	RIO A 303		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1M4G_A_RIOA500","1m4g","RIO","Ribostamycin (DB03615)","Mycobacterium tuberculosis","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","Acetyltransf_9",18,"PHE A 32;ASP A 35;PHE A 36;ASP A 40;VAL A 81;GLU A 82;GLY A 83;SER A 117;SER A 118;SER A 119;ALA A 120;ARG A 121;ARG A 123;ASP A 151;ASP A 152;THR A 155;ASP A 179;TRP A 181","RIO A 500\r"],["1S3Z_A_RIOA500","1s3z","RIO","Ribostamycin (DB03615)","Salmonella enteritidis","AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE","Acetyltransf_1",11,"ARG A 18;TRP A 22;PRO A 23;HIS A 25;TYR B 66;ASN B 68;GLU A 79;ASP A 115;THR A 116;GLU B 136;VAL B 138","RIO A 500\r"],["2BUE_A_RIOA1201","2bue","RIO","Ribostamycin (DB03615)","Escherichia coli","AAC(6')-IB","Acetyltransf_8",16,"TRP A 48;TRP A 49;GLY A 50;GLY A 51;TYR A 65;LEU A 70;GLU A 73;VAL A 75;GLN A 91;TYR A 93;SER A 98;TRP A 102;TRP A 103;ASP A 115;ASP A 152;ASP A 179","RIO A1201\r"],["5IQD_A_RIOA600","5iqd","RIO","Ribostamycin (DB03615)","Staphylococcus aureus","BIFUNCTIONAL AAC\/APH","APH",13,"ASP A 374;SER A 376;ASN A 378;HIS A 379;TYR A 408;GLU A 411;SER A 413;GLU A 415;GLU A 416;VAL A 444;GLU A 445;TYR A 448;GLU A 451","RIO A 600\r"],["6S0S_A_RIOA303","6s0s","RIO","Ribostamycin (DB03615)","Streptomyces kanamyceticus","KANAMYCIN B DIOXYGENASE","PhyH",20,"ASN A 73;PHE A 74;GLN A 80;VAL A 116;SER A 118;GLY A 119;ASN A 120;HIS A 132;LEU A 133;ASP A 134;GLU A 135;CYS A 150;ASP A 152;ARG A 183;GLY A 184;ARG A 213;ALA A 234;THR A 236;TYR A 238;MET A 244","RIO A 303\r"]]